columbia university chemistry phd program

Biological Science Phd Program

The research interests of the Department span a number of fields that are central to modern biology: cell & molecular, computational, developmental, structural biology & molecular biophysics, genetics & genomics, evolutionary biology, chemical biology, microbiology and neurobiology. As a student here you will have the opportunity to receive broadly based training in these areas and to develop research expertise through laboratory rotations and your thesis research. The intimate scale of the Department assures you of close contacts with the faculty and your fellow students while the location of the Department within the wide research community of New York City ensures the maximum possible exposure to exciting scientific developments. We have a steady flow of visitors from the US and abroad who enrich our offerings through seminars, discussions and informal meetings with research groups and faculty.

The Department occupies a modern research facility on the Morningside Heights Campus of Columbia University, a comfortable University neighborhood. The equipment available to you is state of the art, ranging from oligonucleotide synthesizers to electron microscopes. Core facilities for protein biochemistry, cell sorting, transgenic mice and X-ray crystallography are available. A well equipped computer facility is located within the Fairchild Building adjacent to the research laboratories. The new Science and Engineering Library the home to the Digital Science Center is located nearby in the new Northwest Corner Building.

Chemistry and Chemical Physics Phd Program

For more than a century, the Columbia Chemistry Department has played a major role in the development of the study of chemistry in the US. Until World War II, Columbia University dominated the academic scene by numbers, graduating more PhDs and staffing more academic posts in chemistry than any other US university. Since the 1940s, graduate programs have grown and expanded at many other institutions, and now Columbia is known more for quality than for quantity. The department runs one of the best graduate research and training programs in the country, famous for its lively intellectual atmosphere and for the intensity of effort put forth by its faculty and students.

The first year of graduate study is largely given to course work, the course requirements for each student being determined individually in accordance with previous training and interests. To some extent during the first year, and increasingly thereafter, students are engaged in research for the doctoral dissertation. Research is the most important part of the graduate program, and the selection of a sponsor to guide the research is the most important decision a student makes. To help with this decision, every faculty member discusses his or her research at colloquia held during the first term. Students choose a sponsor only after attending all these meetings and talking privately with at least three faculty members. All students are expected to complete the degree requirements and defend their dissertations within five years of entry into the program. The system works well; the percentage of entering students who complete the program is very high, and about twenty-five PhD degrees in Chemistry are awarded by the university each year.

Coordinated Doctoral Programs in Biomedical Sciences

The Coordinated Doctoral Programs in Biomedical Sciences are part of the medical school and the Columbia University Graduate School of Arts and Sciences. The programs are located at the Columbia University Irving Medical Center campus. PhD students have access to more than 250 training faculty when selecting their research direction, ensuring that each student receives optimal training and research experience. We also provide a supportive environment which goes beyond academics.

• Integrated Program in Cellular, Molecular, and Biomedical Studies
• Biochemistry, Molecular Biophysics and Structural Biology
• Stem Cell Biology and Cell Biology
• Microbiology and Immunology
• Pathobiology and Mechanisms of Disease
• Cancer Biology
• Systems Biology
• Cellular & Molecular Physiology and Biophysics
• Genetics & Development
• Molecular Pharmacology & Therapeutics
• Nutritional & Metabolic Biology
• Neurobiology and Behavior

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Doctoral Program

Education and training of doctoral students is a core mission of the Department of Biochemistry and Molecular Biophysics. Faculty members mentor graduate students from the Coordinated Doctoral Programs in Biomedical Sciences at Columbia University Irving Medical Center (CUIMC) as well as from the Departments of Applied Physics, Biological Sciences, Chemistry, Physics, and others at the Arts and Sciences and Manhattanville campuses.

At any given time approximately 50 graduate students are conducting doctoral research in laboratories within the department. After completion of the doctorate, the majority of students go on to postdoctoral positions at leading research institutions.

Prospective students interested in research at the department's laboratories most commonly apply through the Integrated Program in Cellular, Molecular, and Biomedical Studies or the Program in Neurobiology and Behavior, both of which are within the Coordinated Doctoral Programs.

The Integrated Program is an umbrella program that includes more than 200 faculty members from the basic sciences departments at the medical center as well as other campuses of Columbia University. The program presents students with a unique opportunity to obtain individualized training in basic cell and molecular biology, microbiology, structural biology, biophysics, genetics, immunology, neurobiology, and computational biology, as well as translational biomedical disease-related research.

The Program in Neurobiology and Behavior is founded on the principle that the study of the biological roots of behavior is essential for an understanding of animal and human behavior, as well as for insights into the causes and cures of nervous system disorders. The program offers a diverse set of research and academic experiences that reflect the interdisciplinary nature of neuroscience.

University of Missouri

College of Arts and Science

Graduate Program

For prospective students.

The PhD Program in Chemistry at the University of Missouri

Thank you for exploring the possibility of graduate studies at the University of Missouri Department of Chemistry!  The University of Missouri (MU), located in Columbia, Missouri, was established in 1839 and is the flagship campus of the University of Missouri System.  The PhD program in Chemistry at MU has been operating for over 110 years, with the first degrees conferred in 1909.

Graduate students in the Department address cutting-edge research problems using state-of-the-art facilities (including NMR , mass spectrometry, materials characterization, X-ray crystallography , etc).  There are approximately 25 faculty members in the Department and over 90 graduate students.  Research groups in the Department work in the traditional core areas of chemistry including analytical chemistry, inorganic chemistry, organic chemistry, and physical chemistry and also in interdisciplinary fields such as radiochemistry, novel functional materials, medicinal chemistry, chemical biology, astrochemistry, catalysis, archaeometry, nuclear forensics; radiopharmaceuticals, bioimaging, chemical sensors, bioinorganic chemistry, green chemistry, chemistry for sustainable living, environmental chemistry, and surface science.  The groundbreaking research in the Department provides an excellent training-ground for our PhD students.

The educational environment of the PhD program emphasizes personalized mentoring to maximize the student’s scientific development, professional development, productivity, and overall success.  Our PhD students are trained to be creative and adaptable scientists who are able lead research projects in either academic or industrial settings.  As a result, our graduates move forward to excellent positions in pharma, the chemical industry, manufacturing, National Laboratories, Federal Regulatory Agencies, patent law, and academics.  The department values diversity, as outlined by the American Chemical Society :  “(w)e believe in the strength of diversity in all its forms, because inclusion of and respect for diverse people, experiences, and ideas lead to superior solutions to world challenges and advances chemistry as a global, multidisciplinary science”.

Financial Support

All PhD students in the program are provided financial support for the duration of their studies.  This comes in the form of either Research or Teaching Assistantships.  The graduate stipend easily covers the cost of living in Columbia .  The costs of tuition and health insurance are covered as part of the Assistantships (and are not paid by the graduate student).

The City of Columbia

Columbia is a city of 130,000 residents and is very easy to navigate.  There really is no such thing as a long commute in our city.  The Columbia area is home to beautiful City Parks , State Parks , and National Forest ( Mark Twain National Forest .  The city and surrounding area has an extensive network of walking-hiking-biking trails for recreation and commuting.  The city enjoys a variety of wineries , breweries restaurants, and alternative cinema , along with music and film festivals.  In addition to the University of Missouri (with approx. 31,000 total students) Columbia is home to Stephens College and Columbia College (approximately 3,000 students).  Together these institutions of higher education form a vibrant network of international student communities, recreational opportunities, sporting events , and cultural activities .

FOR MORE INFORMATION, PLEASE CONTACT ONE OF US.  BELOW IS OUR CONTACT INFORMATION.

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Undergraduate Office: 340 Havemeyer; 212-854-2163

Departmental Office: 344 Havemeyer; 212-854-2202 https://chem.columbia.edu/

Program Manager for Undergraduate Studies: Dr. Vesna Gasperov, 355 Chandler; 212-854-2017; [email protected]

Biochemistry Advisers: Please see Dr. Gasperov for your initial advising session for Biochemistry.

Biology : (for course planning queries) Prof. John Hunt, 702A Fairchild; 212-854-5443; [email protected] ; (for research and graduate school queries) Prof. James Manley, 1117A Fairchild; 212-854-4647;  [email protected]   Chemistry : Prof. Virginia Cornish, 1209 Northwest Corner Building; 212-854-5209;  [email protected]

Chemistry, the study of molecules, is a central science interesting for its own sake but also necessary as an intellectual link to the other sciences of biology, physics, and environmental science. Faculty find the various disciplines of chemistry fascinating because they establish intellectual bridges between the macroscopic or human-scale world that we see, smell, and touch, and the microscopic world that affects every aspect of our lives. The study of chemistry begins on the microscopic scale and extends to engage a variety of different macroscopic contexts.

Chemistry is currently making its largest impact on society at the nexus between chemistry and biology and the nexus between chemistry and engineering, particularly where new materials are being developed. A typical chemistry laboratory now has more computers than test tubes and no longer smells of rotten eggs.

The chemistry department majors are designed to help students focus on these new developments and to understand the factors influencing the nature of the discipline. Because the science is constantly changing, courses change as well, and while organic and physical chemistry remain the bedrock courses, they too differ greatly from the same courses 40 years ago. Many consider biochemistry to be a foundation course as well. Although different paths within the chemistry major take different trajectories, there is a core that provides the essential foundation students need regardless of the path they choose. Students should consider majoring in chemistry if they share or can develop a fascination with the explanatory power that comes with an advanced understanding of the nature and influence of the microscopic world of molecules.

Students who choose to major in chemistry may elect to continue graduate study in this field and obtain a Ph.D. which is a solid basis for a career in research, either in the industry or in a university. A major in chemistry also provides students with an astonishing range of career choices such as working in the chemical or pharmaceutical industries or in many other businesses where a technical background is highly desirable. Other options include becoming a financial analyst for a technical company, a science writer, a high school chemistry teacher, a patent attorney, an environmental consultant, or a hospital laboratory manager, among others. The choices are both numerous and various as well as intellectually exciting and personally fulfilling.

Advanced Placement

The department grants advanced placement (AP) credit for a score of 4 or 5 or the equivalent. The amount of credit granted is based on the results of the department assessment exam and completion of the requisite course. Students who receive permission to register for  CHEM UN1604 2ND TERM GEN CHEM (INTENSIVE) are granted 3 points of credit; students who receive permission to register for CHEM UN2045 INTENSVE ORGANIC CHEMISTRY - CHEM UN2046 INTENSVE ORG CHEM-FOR 1ST YEAR are granted 6 points of credit. In either case, credit is granted only upon completion of the course with a grade of C or better. Students must complete a department assessment exam prior to registering for either of these courses.

Programs of Study

The Department of Chemistry offers four distinct academic major programs for undergraduates interested in professional-level training and education in the chemical sciences: chemistry, chemical physics, biochemistry and environmental chemistry. For students interested in a program of less extensive study and coursework, the department offers a concentration in chemistry.

Course Information

The results of the department assessment exam are used to advise students which track to pursue. The Department of Chemistry offers three different tracks. Students who wish to take Track 2 or 3 classes must take the department assessment exam. Students who wish to pursue Track 1 classes do not need to take the assessment exam.

Track Information

In the first year, Track 1 students with one year of high school chemistry take a one-year course in general chemistry, and the one-term laboratory course that accompanies it. In the second year, students study organic chemistry, and take organic chemistry laboratory.

Students who qualify by prior assessment during orientation week can place into the advanced tracks. There are two options. Track 2 students take, in the fall term, a special one-term intensive course in general chemistry in place of the one-year course. In the second year, students study organic chemistry and take organic chemistry laboratory. Track 3 students take a one-year course in organic chemistry for first-year students and the one-term intensive general chemistry laboratory course. In the second year, students enroll in physical chemistry and the organic chemistry laboratory course. 

Additional information on the tracks can be found in the Requirements section.

Additional Courses

First-year students may also elect to take   CHEM UN2408 . This seminar focuses on topics in modern chemistry, and is offered to all students who have taken at least one semester of college chemistry and have an interest in chemical research.

Biochemistry ( BIOC GU4501 , BIOC GU4512 ) is recommended for students interested in the biomedical sciences.

Physical chemistry ( CHEM UN3079 - CHEM UN3080 ), a one-year program, requires prior preparation in mathematics and physics. The accompanying laboratory is CHEM UN3085 - CHEM UN3086 .

Also offered are a senior seminar ( CHEM UN3920 ); advanced courses in biochemistry, inorganic, organic, and physical chemistry; and an introduction to research ( CHEM UN3098 ).

Sample Programs

Some typical programs are shown below. Programs are crafted by the student and the Director of Undergraduate Studies and Program Manager to meet individual needs and interests.

• Virginia W. Cornish
• Richard A. Friesner
• Ruben Gonzalez
• Laura Kaufman
• James L. Leighton
• Ann E. McDermott
• Jack R. Norton
• Colin Nuckolls
• Gerard Parkin
• David R. Reichman
• Tomislav Rovis
• Dalibor Sames
• Brent Stockwell
• James J. Valentini
• Latha Venkataraman
• Xiaoyang Zhu

Associate Professors

• Angelo Cacciuto
• Luis Campos
• Jonathan Owen

Assistant Professors

• Timothy Berkelbach
• Milan Delor

Senior Lecturers

• Anna Ghurbanyan
• Sarah Hansen
• Joseph Ulichny
• Robert Beer
• John Decatur
• Charles E. Doubleday
• Christopher Eckdahl
• Ruben Savizky
• Talha Siddiqui

Guidelines for all Chemistry Majors, Concentrators, and Interdepartmental Majors

Students majoring in chemistry or in one of the interdepartmental majors in chemistry should go to the director of undergraduate studies or the undergraduate program manager in the Department of Chemistry to discuss their program of study. Chemistry majors and interdepartmental majors usually postpone part of the Core Curriculum beyond the sophomore year.

Chemistry Tracks

All students who wish to start with Track 2 or 3 courses must take an assessment during orientation week ahead of fall semester. The results of the assessment are used to advise students which track to pursue. Unless otherwise specified below, all students must complete one of the following tracks:

Physics Sequences

Unless otherwise specified below, all students must complete one of the following sequences:

For students with limited background in high school physics:

For students with advanced preparation in physics and mathematics:

Major in Chemistry

Select one of the tracks outlined above in  Guidelines for all Chemistry Majors, Concentrators, and Interdepartmental Majors  and complete the following lectures and labs.

Major in Biochemistry

Major in chemical physics, major in environmental chemistry.

The requirements for this program were modified on February 1, 2016. Students who declared this program before this date should contact the director of undergraduate studies for the department in order to confirm their correct course of study.

Select one of the tracks outlined above in  Guidelines for all Chemistry Majors, Concentrators, and Interdepartmental Majors  and complete the following lectures and labs. 

Concentration in Chemistry

No more than four points of CHEM UN3098 SUPERVISED INDEPENDENT RES   may be counted toward the concentration.

CHEM UN0001 PREPARATION-COLLEGE CHEMISTRY. 0.00 points .

Not for credit toward the bachelor's degree. Given on a Pass/Fail basis only.

Prerequisites: High school algebra or the instructor's permission. Recommended preparation: high school physics and chemistry. Prerequisites: High school algebra or the instructor's permission. Recommended preparation: high school physics and chemistry. This course is preparation for Chemistry UN1403 or the equivalent, as well as for other science courses. It is intended for students who have not attended school for sometime or who do not have a firm grasp of high school chemistry. Topics include inorganic nomenclature, chemical reactions, chemical bonding and its relation to molecular structure, stoichiometry, periodic properties of elements, chemical equilibrium, gas laws, acids and bases, and electrochemistry

Please note that some lab fees have increased. You may consult the  Directory of Classes  for the most up to date fees.

CHEM UN1403 GENERAL CHEMISTRY I-LECTURES. 4.00 points .

CC/GS: Partial Fulfillment of Science Requirement

Corequisites: MATH UN1101 Corequisites: MATH UN1101 Preparation equivalent to one year of high school chemistry is assumed. Students lacking such preparation should plan independent study of chemistry over the summer or take CHEM UN0001 before taking CHEM UN1403 . Topics include stoichiometry, states of matter, nuclear properties, electronic structures of atoms, periodic properties, chemical bonding, molecular geometry, introduction to quantum mechanics and atomic theory, introduction to organic and biological chemistry, solid state and materials science, polymer science and macromolecular structures and coordination chemistry. Although CHEM UN1403 and CHEM UN1404 are separate courses, students are expected to take both terms sequentially. The order of presentation of topics may differ from the order presented here, and from year to year. Students must ensure they register for the recitation that corresponds to the lecture section. When registering, please add your name to the wait list for the recitation corresponding to the lecture section (1405 for lecture sec 001; 1407 for lecture sec 002; 1409 for lecture sec 003; 1411 for lecture sec 004). Information about recitation registration will be sent out before classes begin. DO NOT EMAIL THE INSTRUCTOR. Please check the Directory of Classes for details

CHEM UN1500 GENERAL CHEMISTRY LABORATORY. 3.00 points .

CC/GS: Partial Fulfillment of Science Requirement Lab Fee: $140.

Corequisites: CHEM UN1403 , CHEM UN1404 Corequisites: CHEM UN1403 , CHEM UN1404 An introduction to basic lab techniques of modern experimental chemistry, including quantitative procedures and chemical analysis. Students must register for a Lab Lecture section for this course ( CHEM UN1501 ). Please check the Directory of Classes for details. Please note that CHEM UN1500 is offered in the fall and spring semesters. Mandatory lab check-in will be held during the first week of classes in both the fall and spring semesters. You may be asked to serve as research subjects in studies under direction of the faculty while enrolled in this course ( CHEM UN1500 Sec 1, 2, 5, 7 and CHEM UN1501 Sec 1). Participation in voluntary

CHEM UN1507 INTENSVE GENERAL CHEMISTRY-LAB. 3.00 points .

Prerequisites: CHEM UN1604 or CHEM UN2045 Corequisites: CHEM UN2045 Prerequisites: CHEM UN1604 or CHEM UN2045 Corequisites: CHEM UN2045 A student-centered experimental course intended for students who are taking or have completed CHEM UN1604 (Second Semester General Chemistry Intensive Lecture offered in Fall), CHEM UN2045 (Intensive Organic Chemistry offered in Fall), or CHEM UN2046 (Intensive Organic Chemistry Lecture offered in Spring). The course will provide an introduction to theory and practice of modern experimental chemistry in a contextual, student-centered collaborative learning environment. This course differs from CHEM UN1500 in its pedagogy and its emphasis on instrumentation and methods. Students must also attend the compulsory Mentoring Session. Please check the Directory of Classes for details. Please note that CHEM UN1507 is offered in the fall and spring semesters

CHEM UN1604 2ND TERM GEN CHEM (INTENSIVE). 4.00 points .

Prerequisites: Acceptable performance on the Department placement exam during orientation week AND either a grade of "B" or better in CHEM UN1403 or AP chemistry or the equivalent. Corequisites: MATH UN1102 Prerequisites: Acceptable performance on the Department placement exam during orientation week AND either a grade of "B" or better in CHEM UN1403 or AP chemistry or the equivalent. Please contact Vesna Gasperov ([email protected]) or your academic advisor at CSA for further information. Corequisites: MATH UN1102 Topics include chemical kinetics, thermodynamics and chemical bonding. Students must register simultaneously for a corresponding recitation section. Please check Courseworks or contact the instructor or departmental adviser for additional details. When registering, be sure to add your name to the wait list for the recitation corresponding to the lecture section ( CHEM UN1606 ). Information about registration for the required recitation will be sent out before classes begin. Please expect to also be available for review sessions on Fridays from 8:10am-9:55am

CHEM UN2443 ORGANIC CHEMISTRY I-LECTURES. 4.00 points .

Prerequisites: ( CHEM UN1403 and CHEM UN1404 ) or CHEM UN1604 Prerequisites: ( CHEM UN1403 and CHEM UN1404 ) or CHEM UN1604 The principles of organic chemistry. The structure and reactivity of organic molecules are examined from the standpoint of modern theories of chemistry. Topics include stereochemistry, reactions of organic molecules, mechanisms of organic reactions, syntheses and degradations of organic molecules, and spectroscopic techniques of structure determination. Although CHEM UN2443 and CHEM UN2444 are separate courses, students are expected to take both terms sequentially. Students must ensure they register for the recitation which corresponds to the lecture section. Please check the Directory of Classes for details

CHEM UN2493 ORGANIC CHEM. LAB I TECHNIQUES. 0.00 points .

Lab Fee: $63.00

Prerequisites: ( CHEM UN1403 and CHEM UN1404 ) or ( CHEM UN1604 ) and ( CHEM UN1500 or CHEM UN1507 ) Corequisites: CHEM UN2443 Prerequisites: ( CHEM UN1403 and CHEM UN1404 ) or ( CHEM UN1604 ) and ( CHEM UN1500 or CHEM UN1507 ) Corequisites: CHEM UN2443 Techniques of experimental organic chemistry, with emphasis on understanding fundamental principles underlying the experiments in methodology of solving laboratory problems involving organic molecules. Attendance at the first lab lecture and laboratory session is mandatory. Please note that CHEM UN2493 is the first part of a full year organic chemistry laboratory course. Students must register for the lab lecture section ( CHEM UN2495 ) which corresponds to their lab section. Students must attend ONE lab lecture and ONE lab section every other week. Please contact your advisers for further information

CHEM UN2495 ORGANIC CHEM. LABORATORY I. 1.50 point .

Corequisites: CHEM UN2493 Corequisites: CHEM UN2493 The course is the lab lecture which accompanies the Organic Chemistry Laboratory I (Techniques) course

CHEM UN2545 INTENSIVE ORGANIC CHEM LAB. 3.00 points .

Lab Fee: $125.

Prerequisites: ( CHEM UN2045 and CHEM UN2046 ) and CHEM UN1507 Prerequisites: ( CHEM UN2045 and CHEM UN2046 ) and CHEM UN1507 The lab is intended for students who have taken Intensive Organic Chemistry, CHEM UN2045 - CHEM UN2046 and who intend to major in Chemistry, Biochemistry, Chemical Physics, or Environmental Chemistry

CHEM UN3079 PHYSICAL CHEMISTRY I-LECTURES. 4.00 points .

Prerequisites: ( CHEM UN1403 and CHEM UN1404 ) or ( CHEM UN1604 ) or ( CHEM UN2045 and CHEM UN2046 ) and ( MATH UN1101 and MATH UN1102 ) or ( MATH UN1207 and MATH UN1208 ) and ( PHYS UN1401 and PHYS UN1402 ) PHYS UN1201 - PHYS UN1202 is acceptable; PHYS UN1401 - PHYS UN1402 or the equivalent is HIGHLY recommended. Corequisites: CHEM UN3085 Prerequisites: ( CHEM UN1403 and CHEM UN1404 ) or ( CHEM UN1604 ) or ( CHEM UN2045 and CHEM UN2046 ) and ( MATH UN1101 and MATH UN1102 ) or ( MATH UN1207 and MATH UN1208 ) and ( PHYS UN1401 and PHYS UN1402 ) PHYS UN1201 - PHYS UN1202 is acceptable; PHYS UN1401 - PHYS UN1402 or the equivalent is HIGHLY recommended. Corequisites: CHEM UN3085 Elementary, but comprehensive, treatment of the fundamental laws governing the behavior of individual atoms and molecules and collections of them. CHEM UN3079 covers the thermodynamics of chemical systems at equilibrium and the chemical kinetics of nonequilibrium systems. Although CHEM UN3079 and CHEM UN3080 are separate courses, students are expected to take both terms sequentially. A recitation section is required. Please check the Directory of Classes for details and also speak with the TA for the course

CHEM UN3085 PHYSICL-ANALYTICL LABORATORY I. 4.00 points .

Lab Fee: $125 per term.

Corequisites: CHEM UN3079 Corequisites: CHEM UN3079 A student-centered experimental course intended for students who are co-registered or have completed CHEM UN3079 and CHEM UN3080 . The course emphasizes techniques of experimental physical chemistry and instrumental analysis, including vibrational, electronic, and laser spectroscopy; electroanalytical methods; calorimetry; reaction kinetics; hydrodynamic methods; scanning probe microscopy; applications of computers to reduce experimental data; and computational chemistry. Students must also attend the compulsory Mentoring Session. Please check the Directory of Classes for details

CHEM UN3098 SUPERVISED INDEPENDENT RES. 4.00 points .

Lab Fee: $105 per term.

Prerequisites: the instructor's permission for entrance, and the departmental representative's permission for aggregate points in excess of 12 or less than 4. Prerequisites: the instructors permission for entrance, and the departmental representatives permission for aggregate points in excess of 12 or less than 4. This course may be repeated for credit (see major and concentration requirements). Individual research under the supervision of a member of the staff. Research areas include organic, physical, inorganic, analytical, and biological chemistry. Please note that CHEM UN3098 is offered in the fall and spring semesters

CHEM UN3920 SENIOR SEMINAR. 2.00 points .

Pass/Fail credit only.

Open to senior chemistry, biochemistry, environmental chemistry, and chemical physics majors; senior chemistry concentrators; and students who have taken or are currently enrolled in CHEM UN3098 . Senior seminar provides direct access to modern chemical research through selected studies by the students from active fields of chemical research. Topics to be presented and discussed draw from the current scientific literature and/or UN3098 research

BCHM UN3300 BIOCHEMISTRY. 3.00 points .

Prerequisites: one year each of Introductory Biology and General Chemistry. Corequisites: Organic Chemistry. Biochemistry is the study of the chemical processes within organisms that give rise to the immense complexity of life. This complexity emerges from a highly regulated and coordinated flow of chemical energy from one biomolecule to another. This course serves to familiarize students with the spectrum of biomolecules (carbohydrates, lipids, amino acids, nucleic acids, etc.) as well as the fundamental chemical processes (glycolysis, citric acid cycle, fatty acid metabolism, etc.) that allow life to happen. In particular, this course will employ active learning techniques and critical thinking problem-solving to engage students in answering the question: how is the complexity of life possible? NOTE: While Organic Chemistry is listed as a corequisite, it is highly recommended that you take Organic Chemistry beforehand

BIOC GU4501 BIOCHEM I-STRUCTURE/METABOLISM. 4.00 points .

Undergraduates should register for BIOC UN3501 .

Prerequisites: BIOL UN2005 and BIOL UN2006 and CHEM UN2443 and CHEM UN2444 one year of intro biology and one year of organic chemistry.

In this course, we will study the chemistry of living systems. We will discuss how living systems convert environmental resources into energy, and how they use this energy and these materials to build the molecules required for the diverse functions of life. Finally, we will discuss the applications of such biochemical knowledge to mechanisms of disease and to drug discovery. At a high level, we expect that at the conclusion of the course, you should be able to explain the basic mechanisms by which living systems harness energy from their environment, how living systems construct the molecules necessary for the functions of life, how these processes go awry in a variety of disease, including cancer, and how drugs can be discovered to treat such diseases. Using this knowledge, you will be able to diagram the major metabolic pathways and compare how these pathways are dysregulated in normal tissues in and disease states. In addition, you will learn which techniques are used to uncover this knowledge and how to design and interpret experiments that will address these questions. You will also collaborate with other students in the analysis and interpretation of biochemical data, and be able to communicate, defend and refute interpretations of data. In this course, we assume familiarity with basic concepts of modern biology, so having completed one year of college-level biology is required. In addition, we explore the reaction mechanisms governing a variety of transformations in metabolism. You must have completed one year of organic chemistry prior to taking this course.

CHEM GU4147 ADVANCED ORGANIC CHEMISTRY I. 4.50 points .

Prerequisites: Elementary organic and physical chemistry. Prerequisites: elementary organic and physical chemistry. The mechanisms of organic reactions, structure of organic molecules, and theories of reactivity. How reactive intermediates are recognized and mechanisms are deduced using kinetics, stereochemistry, isotopes, and physical measurements

CHEM GU4148 SYNTHETIC METHDS-ORGANC CHEM. 4.50 points .

Prerequisites: Organic chemistry. This course is intended for graduate students and advanced undergraduate students. The main purpose of the course is to introduce students to modern synthetic chemistry via the selected series of topics (synthetic planning and the logic of organic assembly, classical and new reactions/methods and their use in complex target synthesis). Mechanistic underpinning of the discussed reaction processes will also be briefly discussed. For each module (see the content below), specific examples of syntheses of natural products and/or synthetic materials will be provided. In addition to lectures by Prof. Sames, students will select and present relevant papers in the class (the number of student symposia will depend on the final enrollment in this course). The basic knowledge of transition metal chemistry is recommended for the cross-coupling reactions (i.e. structure, electron counting, and elemental reaction types of transition metals)

CHEM GU4221 QUANTUM CHEMISTRY I. 4.50 points .

Prerequisites: elementary physical chemistry. Basic quantum mechanics: the Schrodinger equation and its interpretation, exact solutions in simple cases, methods or approximations including time-independent and time-dependent perturbation theory, spin and orbital angular momentum, spin-spin interactions, and an introduction to atomic and molecular structure

CHEM GU4230 STATISTICAL THERMODYNAMICS. 4.50 points .

Prerequisites: elementary physical chemistry. Corequisites: CHEM G4221. Topics include the classical and quantum statistical mechanics of gases, liquids, and solids

CHEM GU4312 CHEMICAL BIOLOGY. 4.00 points .

Prerequisites: ( CHEM UN2443 and CHEM UN2444 ) and ( CHEM UN3079 and CHEM UN3080 ) and ( BIOC UN3501 ) , or the equivalent. Prerequisites: ( CHEM UN2443 and CHEM UN2444 ) and ( CHEM UN3079 and CHEM UN3080 ) and ( BIOC UN3501 ) , or the equivalent. Development and application of chemical methods for understanding the molecular mechanisms of cellular processes. Review of the biosynthesis, chemical synthesis, and structure and function of proteins and nucleic acids. Application of chemical methods--including structural biology, enzymology, chemical genetics, and the synthesis of modified biological molecules--to the study of cellular processes--including transcription, translation, and signal transduction

BIOC GU4323 Biophysical Chemistry I. 4 points .

This course provides a rigorous introduction to the theory underlying widely used biophysical methods, which will be illustrated by practical applications to contemporary biomedical research problems. The course has two equally important goals. The first goal is to explicate the fundamental approaches used by physical chemists to understand the behavior of molecules and to develop related analytical tools. The second goal is to prepare students to apply these methods themselves to their own research projects. The course will be divided into seven modules: (i) solution thermodynamics; (ii) hydrodynamic methods; (iii) statistical analysis of experimental data; (iv) basic quantum mechanics; (v) optical spectroscopy with an emphasis on fluorescence; (vi) nuclear magnetic resonance spectroscopy; and (vii) light-scattering and diffraction methods.  The first three modules will be covered during the fall term. In each module, the underlying physical theories and models with be presented and used to derive the mathematical equations applied to the analysis of experimental data. Weekly recitations will emphasize the analysis of real experimental data and understanding the applications of biophysical experimentation in published research papers.

CHEM GR6168 MATERIALS CHEMISTRY IIA. 2.50 points .

Prerequisites: CHEM UN2443 , or the equivalent. Prerequisites: CHEM UN2443 , or the equivalent. This is an introductory course to the emerging field macromolecular materials chemistry. The general topics will be based on the chemistry, self-assembly, and performance of block copolymers and conjugated polymers. Particular emphasis will be devoted to the demands required to drive materials from scientific curiosity to commercialization. At the fundamental level, the course will cover topics on polymerization techniques, electronic structure of organic semiconductors, characterization strategies, nanostructures and self-assembly

CHEM GR8109 CONCISE ORGANOMETALLIC CHEM. 2.50 points .

Main group and transition metal organometallic chemistry: bonding, structure, reactions, kinetics, and mechanisms. The only prerequisites needed include General Chemistry II Lectures (specifically, kinetics, and at the level of UN1404 or UN1604) and Organic Chemistry II Lectures (at the level of UN2046 or UN2444). Advanced knowledge from classes, including but not limited to physical chemistry, inorganic chemistry, advanced organic chemistry, and synthetic methods, is NOT required

Spring 2024

Please note that some lab fees have increased. You may consult the Directory of Classes  for the most up to date fees.

CHEM UN1404 GENERAL CHEMISTRY II-LECTURES. 4.00 points .

Prerequisites: CHEM UN1403 Prerequisites: CHEM UN1403 Although CHEM UN1403 and CHEM UN 1404 are separate courses, students are expected to take both terms sequentially. Topics include gases, kinetic theory of gases, states of matter: liquids and solids, chemical equilibria, applications of equilibria, acids and bases, chemical thermodynamics, energy, enthalpy, entropy, free energy, periodic properties, chemical kinetics, and electrochemistry. The order of presentation of topics may differ from the order presented here, and from year to year. Students must ensure they register for the recitation that corresponds to the lecture section. Please check the Directory of Classes for details

CHEM UN2045 INTENSVE ORGANIC CHEMISTRY. 4.00 points .

Prerequisites: A grade of 5 on the Chemistry Advanced Placement exam and an acceptable grade on the Department placement exam or an acceptable grade in CHEM UN1604 . Corequisites: CHEM UN1507 Prerequisites: A grade of 5 on the Chemistry Advanced Placement exam and an acceptable grade on the Department placement exam. Corequisites: CHEM UN1507 Premedical students may take CHEM UN2045 , CHEM UN2046 , CHEM UN1507 and CHEM UN2545 to meet the minimum requirements for admission to medical school. This course covers the same material as CHEM UN2443 - CHEM UN2444 , but is intended for students who have learned the principles of general chemistry in high school OR have completed CHEM UN1604 in their first year at Columbia. First year students enrolled in CHEM UN2045 - CHEM UN2046 are expected to enroll concurrently in CHEM UN1507 . Although CHEM UN2045 and CHEM UN2046 are separate courses, students are expected to take both terms sequentially. A recitation section is required. Please check the Directory of Classes for details and also speak with the TA for the course

CHEM UN2408 1ST YEAR SEM IN CHEMICAL RES. 1.00 point .

Prerequisites: CHEM UN1403 or CHEM UN1604 or CHEM UN2045 or the instructor's permission. Prerequisites: CHEM UN1403 or CHEM UN1604 or CHEM UN2045 or the instructors permission. A one-hour weekly lecture, discussion, and critical analysis of topics that reflect problems in modern chemistry, with emphasis on current areas of active chemical research

CHEM UN2444 ORGANIC CHEMSTRY II-LECTURES. 4.00 points .

Prerequisites: CHEM UN1404 or CHEM UN1604 and CHEM UN1500 and CHEM UN2443 Prerequisites: CHEM UN1404 or CHEM UN1604 , CHEM UN1500 and CHEMUN2443. The principles of organic chemistry. The structure and reactivity of organic molecules are examined from the standpoint of modern theories of chemistry. Topics include stereochemistry, reactions of organic molecules, mechanisms of organic reactions, syntheses and degradations of organic molecules, and spectroscopic techniques of structure determination. Although CHEM UN2443 and CHEM UN2444 are separate courses, students are expected to take both terms sequentially. Students must ensure they register for the recitation which corresponds to the lecture section. Please check the Directory of Classes for details

CHEM UN2494 ORGANIC CHEM. LAB II SYNTHESIS. 0.00 points .

Lab Fee: $62.00

Prerequisites: ( CHEM UN1403 and CHEM UN1404 ) and CHEM UN1500 and CHEM UN2493 Corequisites: CHEM UN2444 Prerequisites: CHEM W1403-CHEM W1404; CHEM W1500; CHEM W2493. Corequisites: CHEM W2444 . Please note that you must complete CHEM W2493 before you register for CHEM W2494. This lab introduces students to experimental design and trains students in the execution and evaluation of scientific data. The technique experiments in the first half of the course (CHEM W2493) teach students to develop and master the required experimental skills to perform the challenging synthesis experiments in the second semester. The learning outcomes for this lab are the knowledge and experimental skills associated with the most important synthetic routes widely used in industrial and research environments. Attendance at the first lab lecture and laboratory session is mandatory. Please note that CHEM W2494 is the second part of a full year organic chemistry laboratory course. Students must register for the lab lecture section (CHEM W2496) which corresponds to their lab section. Students must attend ONE lab lecture and ONE lab section every other week. Please contact your advisors for further information

CHEM UN2496 ORGANIC CHEM. LABORATORY II. 1.50 point .

Corequisites: CHEM UN2494

The course is the lab lecture which accompanies the Organic Chemistry Laboratory II (Synthesis) course.

CHEM UN3080 PHYSICAL CHEMISTRY II-LECTURES. 4.00 points .

Prerequisites: CHEM UN3079 Corequisites: CHEM UN3086 Prerequisites: CHEM UN3079 Corequisites: CHEM UN3086 CHEM UN3080 covers the quantum mechanics of atoms and molecules, the quantum statistical mechanics of chemical systems, and the connection of statistical mechanics to thermodynamics. Although CHEM UN3079 and CHEM UN3080 are separate courses, students are expected to take both terms sequentially. A recitation section is required. Please check the Directory of Classes for details and also speak with the TA for the course

CHEM UN3086 PHYSICL-ANALYTCL LABORATORY II. 4.00 points .

Prerequisites: CHEM UN3085 , CHEM UN3080 is acceptable corequisite for CHEM UN3086 . Prerequisites: CHEM UN3085 , CHEM UN3080 is acceptable corequisite for CHEM UN3086 . A student-centered experimental course intended for students who are co-registered or have complete CHEM UN3079 and CHEM UN3080 . The course emphasizes techniques of experimental physical chemistry and instrumental analysis, including vibrational, electronic, and laser spectroscopy; electroanalytical methods; calorimetry; reaction kinetics; hydrodynamic methods; scanning probe microscopy; applications of computers to reduce experimental data; and computational chemistry. Students must also attend the compulsory Mentoring Session. Please check the Directory of Classes for details

CHEM UN3546 ADVANCED ORGANIC CHEMISTRY LAB. 3.00 points .

Laboratory Fee: $125.

Prerequisites: CHEM UN2493 and CHEM UN2494 , or the equivalent. Prerequisites: CHEM UN2493 and CHEM UN2494 , or the equivalent. A project laboratory with emphasis on complex synthesis and advanced techniques including qualitative organic analysis and instrumentation

CHEM GU4071 INORGANIC CHEMISTRY. 4.50 points .

Prerequisites: ( CHEM UN1403 and CHEM UN1404 ) or ( CHEM UN1604 ) or ( CHEM UN2045 and CHEM UN2046 ) , or the equivalent. Prerequisites: ( CHEM UN1403 and CHEM UN1404 ) or ( CHEM UN1604 ) or ( CHEM UN2045 and CHEM UN2046 ) , or the equivalent. Principles governing the structure and reactivity of inorganic compounds surveyed from experimental and theoretical viewpoints. Topics include inorganic solids, aqueous and nonaqueous solutions, the chemistry of selected main group elements, transition metal chemistry, metal clusters, metal carbonyls, and organometallic chemistry, bonding and resonance, symmetry and molecular orbitals, and spectroscopy

CHEM GU4102 CHEMISTRY FOR THE BRAIN. 4.50 points .

This course was upgraded from 2.5 to 4.5 and assigned a new number.

Prerequisites: Organic chemistry and biology courses, neuroscience or neurobiology recommended, but not required. Prerequisites: Organic chemistry and biology courses, neuroscience or neurobiology recommended, but not required. The study of the brain is one of the most exciting frontiers in science and medicine today. Although neuroscience is by nature a multi-disciplinary effort, chemistry has played many critical roles in the development of modern neuroscience, neuropharmacology, and brain imaging. Chemistry, and the chemical probes it generates, such as molecular modulators, therapeutics, imaging agents, sensors, or actuators, will continue to impact neuroscience on both preclinical and clinical levels. In this course, two major themes will be discussed. In the first one, titled Imaging brain function with chemical tools, we will discuss molecular designs and functional parameters of widely used fluorescent sensors in neuroscience (calcium, voltage, and neurotransmitter sensors), their impact on neuroscience, pros and cons of genetically encoded sensors versus chemical probes, and translatability of these approaches to the human brain. In the second major theme, titled Perturbation of the brain function with chemical tools, we will examine psychoactive substances, the basics of medicinal chemistry, brain receptor activation mechanisms and coupled signaling pathways, and their effects on circuit and brain function. We will also discuss recent approaches, failures and successes in the treatment of neurodegenerative and psychiatric disorders. Recent advances in precise brain function perturbation by light (optogenetics and photopharmacology) will also be introduced. In the context of both themes we will discuss the current and future possibilities for the design of novel materials, drawing on the wide molecular structural space (small molecules, proteins, polymers, nanomaterials), aimed at monitoring, modulating, and repairing human brain function. This course is intended for students (undergraduate and graduate) from the science, engineering and medical departments

CHEM GU4111 APPLICATIONS OF NMR SPECTROSCOPY TO INOR. 2.50 points .

The use of multinuclear NMR spectroscopy in the determination of the structures of inorganic molecules and the use of dynamic NMR spectroscopy (variable temperature NMR and magnetization transfer techniques) to provide information concerned with reaction mechanisms

CHEM GU4145 NMR SPECTROSCOPY. 1.00 point .

Prerequisites: elementary organic chemistry. Prerequisites: elementary organic chemistry. Introduction to theory and practice of NMR spectroscopy. Instrumental aspects, basic NMR theory, NOE, and a survey of 2D methods are covered

CHEM GU4313 Peptide and Protein Chemistry. 4.00 points .

The goal of this course is to explore how chemical methods and concepts have impacted our ability to understand and manipulate protein structure and function. We will navigate this subject through a combination of lectures and structured discussions on research articles from the literature. The course is divided into three segments: (1) In the first part, we will review the rudiments of protein structure and function, then delve into various aspects of enzyme chemistry and polypeptide biosynthesis. (2) In the second part of the course, we will cover synthetic methods to produce and chemically modify peptides and proteins. (3) In the final part, we will discuss chemical approaches to control protein function and monitor protein activity, focusing on methods that use small molecules and mass spectrometry proteomics

CHEM GU4324 BIOPHYSICAL CHEMISTRY II. 4.50 points .

BIOC GU4512 MOLECULAR BIOLOGY. 3.00 points .

Prerequisites: one year of biology. Recommended but not required: BIOC UN3501 Prerequisites: one year of biology. This is a lecture course designed for advanced undergraduates and graduate students. The focus is on understanding at the molecular level how genetic information is stored within the cell and how it is regulated. Topics covered include genome organization, DNA replication, transcription, RNA processing, and translation. This course will also emphasize the critical analysis of the scientific literature and help students understand how to identify important biological problems and how to address them experimentally. SPS and TC students may register for this course, but they must first obtain the written permission of the instructor, by filling out a paper Registration Adjustment Form (Add/Drop form). The form can be downloaded at the URL below, but must be signed by the instructor and returned to the office of the registrar. http://registrar.columbia.edu/sites/default/files/content/reg-adjustment.pdf

CHEM GR6169 MATERIALS CHEMISTRY IIB. 2.50 points .

Prerequisites: CHEM UN2443 , or the equivalent. Prerequisites: CHEM UN2443 , or the equivalent

CHEM GR6231 INTERMEDIATE STATISTICAL MECH. 2.50 points .

Prerequisites: CHEM GU4221 and CHEM GU4230

Phase transitions and critical phenomena; renormalization group methods; classical theory of fluids.

CHEM G8108 Group Theory. 2.5 points .

Not offered during 2023-2024 academic year.

Chemical applications of group theory: structure, bonding and spectroscopy. Ligand field and molecular orbital theories.

CHEM GR8232 ADV STATISTICAL MECHANICS. 2.50 points .

Prerequisites: CHEM GU4221 and CHEM GU4230 , or their equivalents.

Stochastic processes; Brownian motion; Langevin equations and fluctuation-dissipation theorems; reaction rate theory; time correlation functions and linear response theory.

Courses Offered in Alternate Years

Please contact the Undergraduate Program Manager, Vesna Gasperov ([email protected]), for further information.

CHEM GU4103 ORGANOMETALLIC CHEMISTRY. 4.50 points .

Prerequisites: ( CHEM UN2443 and CHEM UN2444 ) , or the equivalent. Some background in inorganic and physical chemistry is helpful but not required.

Main group and transition metal organometallic chemistry: bonding, structure, reactions, kinetics, and mechanisms.

CHEM GU4104 STRUCTURAL METHODS IN INORGANIC CHEMISTR. 2.50 points .

The determination of structures by diffraction methods, focusing on single crystal X-ray diffraction, is described. Emphasis is placed on a critical evaluation of published data.

CHEM GU4154 Chemical Characterization for Synthetic Chemists. 3 points .

Prerequisites: Columbia University’s laboratory safety certification is required. One year each of (i) general chemistry lecture/lab; (ii) organic or inorganic chemistry lecture/lab; and (iii) research experience in a chemistry lab are recommended.

This course will teach synthetic chemists to use mass spectrometry, analytical chromatography, and single-crystal X-ray diffraction as tools for research in synthetic chemistry. The teaching approach will be practical with an emphasis on hands-on experience. Students will gain: (1) A user-level understanding of the theory of these analytical methods. (2) Hands-on proficiency with a variety of instruments available at Columbia. (3) An introduction to advanced instrument capabilities and an awareness of their applications. (4) Proficiency in processing and interpreting data.

CHEM GU4210 Writing Workshop for Chemists. 1 point .

Prerequisites: recommended for undergraduate students to have taken at least one semester of independent research.

This course offers undergraduate and graduate students an introduction to scientific writing and provides an opportunity for them to become more familiar with the skill and craft of communicating complex scientific research. This course will provide students with the basic grammatical, stylistic and practical skills required to write effective academic journal articles, theses, or research proposals. In addition, through an innovative partnership with Columbia University Libraries' Digital Science Center, students will learn how to apply these basic skills to their writing through the use of state-of-the-art software and on-line resources. Regular opportunities to write, peer edit and revise throughout the semester will allow students to put what they are learning into immediate practice. It is recommended that undergraduates have taken at least one semester of research for credit before taking this course. Undergraduates should plan to take this course after taking the required Core course University Writing.

CHEM GR6222 QUANTUM CHEMISTRY II. 2.50 points .

Prerequisites: CHEM GU4221 Prerequisites: CHEM GU4221 Atomic and molecular quantum mechanics: fundamentals of electronic structure, many-body wave functions and operators, Hartree-Fock and density functional theory, the Dirac equation

CHEM GR8106 KINETICS. 2.50 points .

Kinetics and mechanisms of inorganic reactions.

CHEM GR8120 Polymers in Nanotechnology. 2.5 points .

Polymeric materials have long been ubiquitous items and played important roles in revolutionizing the way we live. Due to the advent of modern polymerization fabrication strategies, polymers are rapidly gaining interest for the development of next generation devices and medical treatment. This course will focus on the chemistry polymers and their use as nanostructured materials created by self-assembly and top-down fabrication techniques. Specifically, the class will be divided into two sections describing the uses of organic nanostructures on a) surfaces and b) as particles. Patterned surfaces will be described in terms of photo-, imprint-, and block copolymer lithography. The preparation of nanoparticles through polymer synthesis, dendrimers, and mechanical manipulation will be the second part.

CHEM GR8223 QUANTUM CHEMISTRY III. 2.50 points .

Prerequisites: CHEM G6222 .

Nonlinear spectroscopy: second harmonic and vibrational sum frequency generation; applications to surface and colloidal nano-microparticle interfaces; nonradiative molecular processes.

CHEM GR8349 Research Ethics & Philosophy. 2.5 points .

This lecture course aims to address philosophical and ethical questions in scientific research.  What are the most important traits of successful scientists whose discoveries have greatly benefited humanity (and led to Nobel Prizes)?  What distinguishes great science from mediocre or pathological "science"?  What are the ethical standards of scientific research?  How do we identify scientific misconduct or fraud?  Why are ethical standards so critical to the integrity of the research enterprise?  The course requires extensive participation of students in the form of discussions and debates.  Grades will be based on participation, writing assignments, and one oral presentation.

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Message From Dr. Cory Abate-Shen

Read a message from the Chair of the Department of Molecular Pharmacology and Therapeutics.

Featured Lab: Concepcion Lab

The Concepcion lab studies how chromatin deregulation impacts tumor evolution with a focus on lung cancer.

Graduate Program

Learn how to apply.

Get all the details on how to apply to The Molecular Pharmacology & Therapeutics Graduate Program.

Welcome to our new Graduate Program!

Pharmacology – the study of how drugs or other agents affect cells and living organisms - is a foundational science that intersects with many disciplines in basic science and human disease. Our graduate program emulates the breadth of pharmacology by providing our students with a solid foundation and broad training in cellular and organismal mechanisms, as well as translational science.  The scientific focus of the program is to merge basic science research with emergent research in developing new avenues for therapeutic interventions. Faculty in the program can be focused on developing a basic biological understanding of mammalian organ systems, developing conceptually new avenues/technologies for therapeutics, or combining both of these approaches in an interdisciplinary manner.

Our graduate program has recently been re-vamped to create a modern, vibrant program that is well-aligned with both the historical foundations and new strategic vision of the department. To realize this vision, we have new leadership, co-directors Dr. Nikhil Sharma and Dr. Yonghao Yu, whose research is focused in areas that are vital to pharmacology.  

Our program is ideal for students who are interested in studying basic cellular mechanisms with an emphasis on their application to human disease.  The research interests of our program faculty encompass all areas of modern pharmacology, including cancer pharmacology, cardiovascular pharmacology, and neuropharmacology. The incorporation of novel interdisciplinary approaches (e.g., chemical biology) towards the development of therapeutic strategies is also emphasized. Our graduate program faculty draw from several basic science and clinical departments at Columbia University Irving Medical Center, as well as Columbia University, which enables seamless collaborative and interdisciplinary interactions for our students.

Although rigorous, our program is individualized to each student, allowing students to gain a strong foundation in pharmacology, while adapting the specific educational components to the specific research interests of each student. Training in the first year consists of courses aligned with the integrated program in cellular, molecular, and biomedical studies (CMBS), as well as research rotations in the laboratories of approved program faculty.  In the second year, students begin their thesis research and continue to take their remaining core courses as well as elective courses relevant to their thesis work. At the end of the second year, students take their qualifying exam, for which they prepare and defend a research proposal that is related to their intended thesis research. Subsequent years are devoted to the research, writing and defense of their PhD thesis. As they advance in their degree, students benefit from the advice of their faculty mentor, an advisory committee of expert faculty with whom they meet regularly, and our outstanding and dedicated program co-directors, Dr. Nikhil Sharma and Dr. Yonghao Yu.

Students benefit from the rewarding environment at Columbia University, which is rich in diversity and has unparalleled faculty. Students also benefit from the cultural environment of New York City, with its many museums, theaters, and historical venues.

Nikhil Sharma, PhD

• Assistant Professor of Molecular Pharmacology and Therapeutics
• [email protected]

Yonghao Yu, PhD

• Professor in the Department of Molecular Pharmacology and Therapeutics
• [email protected]

Participating Faculty

Graduate program requirements.

Get more information on applying or answers to questions about the Molecular Pharmacology & Therapeutics Graduate Program.