MD-PhD, Combined Degree

School of medicine, md - phd, combined degree program.

From its inception, the physician-scientist has been a hallmark of Johns Hopkins medicine and the Johns Hopkins School of Medicine. Indeed, the Hopkins tri-emblem represents the three core values of the institution: teaching, patient care, and research.

The Johns Hopkins School of Medicine offers a variety of opportunities for the training of medical scientists, including a combined curriculum leading to both MD and PhD degrees.  This enables students who aspire to careers in academic medicine to obtain intensive training in specialized areas of the biomedical sciences in addition to top-flight medical training. The traditional diversity and flexibility of the educational opportunities at Johns Hopkins permit the design of individualized programs to meet the needs of students with a variety of interests, educational backgrounds, and career goals.

To accomplish our training goals, we expect students to fully commit to medical training while in medical school and research training while in graduate school.  However, we also take important steps to ensure that students are exposed to the intersection of both worlds early in their training, as well as given the professional and career development advice they need to succeed.

In a word, the MD-PhD curriculum at Johns Hopkins is flexible. Most students decide to complete the first two years of medical school before they begin graduate school and finish the last two years of their medical training after completing their thesis work (see the Timeline below). However, students who want more first-hand experience in clinical medicine before beginning graduate work can elect to complete three years of medical school, followed by their graduate training, and then the last year of medical school. This can give them a better appreciation of the potential clinical relevance of their research. In making a choice, trainees consult extensively with the Program Director, the Dean of Students, members of the MD-PhD Committee, prospective research mentors, and their faculty advisors. Students in the MD-PhD Program are accepted to all graduate programs, so decisions regarding graduate training programs can be made with a strong understanding of each program.  The MD-PhD Committee is responsible for program oversight and admissions.  Students complete MD-PhD training on average in eight years.

Johns Hopkins interdisciplinary organizational structure means each faculty member may be affiliated with several clinical departments, research sections, and graduate programs. 

Formal graduate programs in the School of Medicine encompass the following areas: Biochemistry, Cellular, and Molecular Biology; Biological Chemistry; Biomedical Engineering; Molecular Biophysics; Functional Anatomy and Human Evolutionary Studies; Cell Biology; Cellular and Molecular Medicine; History of Medicine; Human Genetics; Immunology; Neuroscience; Pathobiology; Pharmacology and Molecular Sciences, and Cellular and Molecular Physiology. Students are also eligible to obtain their PhD in one of the 11 graduate programs at the Bloomberg School of Public Health or the School of Arts and Sciences on the Homewood Campus.  

The MD-PhD Program also sponsors special seminars and lectures, and maintains a dedicated library, the Paul Talalay MD-PhD Library, to enrich the educational opportunities of all MD-PhD students. Efforts are made to acquaint MD-PhD candidates with the major advances, concepts, and cutting-edge techniques in contemporary medicine and biomedical sciences.  We also create an environment that promotes  collegiality and a more intimate personal contact with successful medical scientists in this institution.

Admission Procedures.  Individuals who wish to apply for admission to the combined MD-PhD Program of the School of Medicine must submit an application through AMCAS  in which they will indicate the MD-PhD Program.  Once the AMCAS application has been verified and submitted to Hopkins, the applicant will receive an invitation to complete the Hopkins Secondary Application.  Here the applicant will submit the additional materials required for the combined degree.  Johns Hopkins does not allow applicants to apply to both the traditional MD program and the combined program during the same cycle.   

All combined-degree applications are reviewed by a subcommittee of the  MD-PhD Committee , which is comprised of faculty from the basic sciences and clinical arena, as well as faculty from the Bloomberg School of Public Health.  A separate Graduate School application is not necessary. The MD-PhD Committee determines whether or not an interview is indicated.  In general, the committee is looking for students with a passion for research and a commitment to medicine.  This assessment is based on the applicant’s research experience, letters of recommendation, academic performance and extracurricular activities. The Committee considers standardized test scores only in the context of the applicant’s other credentials. If an interview is granted, the applicant is notified by the MD-PhD Office and after the applicant accepts, the process for scheduling an interview begins.  Interview visits generally occur over two days. Applicants are interviewed by members of the MD-PhD Committee and other faculty members who share their research interests. Applicants have many opportunities to meet with current students and tour the campus during their visit. 

Approximately 10-12 MD-PhD students matriculate each year. Students who matriculate to the traditional MD Program but have a clearly demonstrated interest and experience in scientific research, are eligible to apply to the combined MD-PhD Program.  These students may apply for admission during the fall of their first or second year of medical school.  These qualified applicants are evaluated and placed in the pool for the current application cycle and will be considered for MSTP funding.  

All eligible applicants who are admitted to the MD-PhD Program are funded by the NIH Medical Scientist Training Program (MSTP) Award.  This program, supported by the National Institutes of Health, provides full tuition, stipend, and medical and dental insurance for students. Due to federal restrictions, only U.S. citizens and permanent residents are eligible for MSTP funding.  

Graduates of The Johns Hopkins University School of Medicine MD-PhD Program have gone on to become leaders in many areas of academic medicine.  Advice on the scope and opportunities offered by the MD-PhD Program may be obtained from the Director or Administrative Director.

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Graduate Programs

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As a premier research and land grant institution, the University of Maryland houses more than 230 graduate programs, enrolls nearly 11,000 graduate students, and confers approximately 2,800 degrees annually. The Graduate School takes pride in leading this effort and in collaborating with the colleges and schools of the university to provide our students with an outstanding educational experience. Explore this section to learn more about our outstanding  doctoral and master’s programs , as well as our stellar  graduate certificate programs .

What It's Like to Do an MD-PhD Program

New section.

Two medical students answer questions about what it's like to do an MD-PhD program.

md phd programs

Elias (Eli) Wisdom

Undergraduate:   Pacific University, Oregon Major:   BS, Biology Medical school:  Oregon Health & Science University (OHSU) Anticipated Graduation Year:  2028 Bio: Eli Wisdom is an MD-PhD student at Oregon Health & Science University (OHSU) studying the molecular mechanisms of Parkinson’s Disease. He grew up in the small rural town of La Grande, Oregon, where he gained a deep appreciation for community and service and a fascination with the natural world. At Pacific University, he completed his degree in Biology while also playing varsity baseball. After graduating, he was as an Associate in Neuroscience at Yale School of Medicine for two years before starting an MD-PhD program. Outside of school, he enjoys competing in triathlons, camping, and spending time with family.

md phd programs

Sreya Sanyal

Undergraduate:  New Jersey Institute of Technology        Major:  Biology & History Double Major Medical school:   Rutgers Robert Wood Johnson Medical School Anticipated Graduation Year:  2031 Bio: Sreya Sanyal is a MD-PhD student at Robert Wood Johnson Medical School and Princeton University. She is Bengali, and she aspires to become a laboratory principal investigator in the field of oncology. Outside of academia, she enjoys singing, cooking, going to museums, and lifting at the gym.  

Why did you decide to pursue an MD-PhD program?

Eli:  As an undergraduate student, I found my first biomedical research experience to be quite thrilling, and seriously considered pursuing a career in research. Medical school had surfaced as an opportunity, too, as I was deeply passionate about serving others and caring for the sick, but I felt that basic science research was the backbone of advancing clinical care. I first learned about combined MD-PhD programs during my senior year when I was taking part in a summer research program at another academic institute. I learned that in a dual-degree program, I could become rigorously trained as a research scientist and as a physician — and could do both in my future career. To learn more, I reached out to a few physician-scientists who shared how much they loved their careers. In the clinic, their patients and associated medical problems provided new ideas for exploration in the laboratory. And in the laboratory, the insights they gained could inform the way they treated their patients. Sreya:  I’ve wanted to become an oncologist ever since I was 11 and my mother died from gastric cancer. When I shadowed hematologist oncologists in academic settings, I became more interested in their work in clinical trials and research. Entering college, I explored translational research through my undergraduate biomedical engineering lab experiences. As I met more people in the field of drug development and oncology, I realized that I wanted to be at the cutting edge of this work, but I still had the desire to see patients. Through a lot of soul searching and luck, I was able to embark on a career in medical research by pursuing an MD-PhD. Using my training as a physician-scientist, I plan to establish my own lab or work in other ways to improve translational research in the oncological space.

What kinds of career options does the MD-PhD program give you?

Eli:   From my experience, rigorous training in medicine and scientific research prepares you best for a career in academic medicine. This often means working at a large teaching hospital, where you have an opportunity to conduct independent scientific research, care for patients, and teach students. While it can differ depending on the medical specialty or the individual, a typical physician-scientist may spend 80% of their time conducting research and 20% caring for patients.  However, there are many other career paths available to MD-PhD graduates. Students may also pursue careers working for private research organizations, pharmaceutical and biotechnology companies, or government agencies.  Sreya:  In my experience as an MD-PhD student interested in oncology, I have a wide array of career options to explore. As a clinician-scientist, I can lead research teams and conduct studies in cancer biology, treatment approaches, and translational medicine. In these roles, I can also mentor students interested in my field, allowing me to advance scientific knowledge while shaping the next generation of researchers. Alternatively, I could directly impact patients' lives by increasing my clinical time spent as an oncologist, developing personalized treatment plans, and contributing to clinical trials. The pharmaceutical and biotechnology industries also present exciting opportunities for me where I would be able to work on drug development, clinical research, or medical affairs, playing an essential role in bringing innovative therapies to market. With my combined medical and research expertise, I am well-equipped to make a meaningful difference in oncology through various rewarding career paths.

What type of research experience did you have before entering the program?

Eli: I attended a liberal arts college where students engaged in scientific research through 2- to 4-month long classes, which were combined lecture and laboratory experiences. Building on excitement from these courses, I pursued a summer research internship at a large biomedical research institute the summer prior to my senior year. I loved this initial exposure to working in a high-powered scientific research center. From working in state-of-the-art reach laboratories, to solving scientific problems in creative ways, and watching physicians bounce between research and patient care — I was hooked.  Sreya:  Before starting my current program, I had two significant research experiences. First, I worked in a lab that focused on creating materials for drug delivery in the field of biomedical engineering. We used special gels to deliver important substances to specific parts of the body, which had significant effects on the surrounding tissues, such as promoting blood vessel growth and blocking certain enzymes. I spent about ten hours a week for three years in this lab and contributed to three published papers.

Secondly, I worked at a research institute where I studied mice that were genetically modified to show signs of anthrax toxin exposure. These modified toxins could be controlled to specifically target tumor cells in the body. I dedicated forty hours a week to this research, and as a result, we have two research papers in progress for publication

How did you prepare to apply to MD-PhD programs?

Eli: Since I had played varsity baseball throughout college (which was impactful training in its own right), I had limited time for research as an undergraduate. So, I decided to pursue an extended research position before applying to MD-PhD programs. After sending several emails to laboratories across the U.S. and applying to many formal postbacc research programs, I took a two-year job as a postgraduate researcher at an academic research institute. During my time working on a project in a laboratory, I also volunteered at the connected hospital. This allowed me to experience what it was like to conduct independent research during the first part of my day, then care for patients in the afternoon. This experience only confirmed my deeply held passions for both medicine and science, but also exposed me to the challenges that both careers entailed. I felt much more confident in my decision to pursue a dual-degree knowing these insights.

What is your favorite part about being an MD-PhD student?

Eli: Thus far, my favorite part of my training has been directly experiencing the intersection of clinical care and research. During the first two years of the MD-PhD, I was mainly focused on medical school courses and preparing for the first board exam. But now, as I am beginning my PhD, I am realizing how medical school has broadened my perspective. When I read research papers or craft a plan to tackle a hypothesis, I feel empowered with the knowledge I learned in my didactic medical school courses. For example, during one of my PhD research rotations, a scientist was having difficulty delivering a therapeutic to the brains of the mice they were studying. Immediately I recalled from my medical school courses how mannitol could be co-infused to transiently open the blood-brain barrier for drug delivery. It could easily be translated to this scenario. Similarly, my experiences with clinic patients have benefited from my MD-PhD training. Often, it can be as simple as the ability to explain to a patient or their family, the exact mechanism of a drug and the reason it could be effective for their ailment. Or, informing them about current basic science efforts in the field or current clinical trials they might be eligible for. As I advance further into my training, I am eager to see how clinical care and laboratory research can become even more intertwined. Sreya:  I am very excited to learn new techniques and approaches to my field of interest. I am also glad that for MD-PhD students in my program, there is a huge emphasis on lifestyle and work/life balance. Many students in my program have become engaged, or married, and are starting families, while many medical students may feel pressure to push these milestones off. Being an MD-PhD student is a huge commitment, so I am especially grateful for all of the personal and professional support my program has to offer.

What do you wish you’d known before you started the program?

Eli: I wish I had known how important it would be to keep an open mind about the research topics that interested me most. I began the MD-PhD program with a rigid focus on a certain topic, thinking that it was the only topic that gave me real excitement. It was also the topic I was most versed in and comfortable in. But during my medical school courses, I was suddenly overwhelmed with several fascinating questions and problems that all seemed equally thrilling. It took a fair bit of mental wrestling with myself to broaden my own research interests and muster up the courage to explore a field I was fascinated with even if I didn’t have the most experience in it quite yet. Luckily, MD-PhD programs are usually quite supportive of students exploring new topics of interest and are eager to see you follow your motivations.

Sreya:  One of the most important aspects to consider for MD-PhD students is the idea that this path is a marathon, not a sprint. There is a lot of temptation to overload on clubs, leadership, research, etc., to keep pace with MD colleagues, but in the long run, an MD-PhD is about the quality and depth of training. It’s important to build healthy habits, strong social relationships, and enjoy activities in a sustainable manner, since MD-PhD students have to do another graduate degree on top of medical training.

What advice would you give a student considering an MD-PhD program?

Eli:  My advice is to accrue as many experiences as you can in medicine and research before applying. Through these, you can understand if pursuing both an MD and a PhD is the best fit for you, or, if you’d be completely satisfied pursuing a career with only training in one discipline. If you can, shadow physicians at both large academic hospitals and private practices. This can teach you if you’d enjoy treating patients daily and give you insight into how your experience will vary based on the setting. Seek out research experiences as early as possible. This may be difficult to procure, but having a longitudinal research experience that encompasses the successes and failures of science will inform you if this should be your future career. If you can, ask for opportunities to experience what it’s like to write a grant or an academic research article. These are not easy to write, yet they encompass a significant amount of time for professional physician-scientists, so, it is important to learn if you’d enjoy (or at least tolerate) the academic writing load. Lastly, don’t be intimidated by the amount time it takes to complete an MD-PhD. Yes, it is longer than most post-graduate training and takes up a significant portion of your early life. But it is a unique and worthy career path that is much needed in service to society. Sreya:  My advice to anyone considering an MD-PhD would be to get both a variety and depth of research experiences. As a student, it’s very easy to continue down a path you already started, but you must try to explore before you commit to any one approach. MD-PhD programs appreciate students who know what they would like to research and the only way to discover this is to pursue broad research experiences. That said, once you find what drives and excites you, it’s important to stick with it and maintain good relationships with your PIs and mentors. It’s a small world among physician-scientists, so depth of work and networking will help you achieve and further your goals. Above all, remember that an MD-PhD is not necessary to do research as a physician. The goal of an MD-PhD is to provide the specific training needed to conduct research above and beyond what a physician alone can do. In this case, you must really be sure that research is fulfilling and allows you to achieve your career goals when applying to programs, as they will ask you about your aspirations.

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Translating Pre-Medical Experiences into Clinical Skills

Michael Foster | May 3, 2023

Your time before medical school is golden. It is a unique time to explore where your passions lie (both within and beyond medicine) and lay a strong foundation of the inter- and intrapersonal skills needed for you to be the best physician you can be. The best advice is simple: challenge yourself, be honest, and have fun! […]

The AAMC offers trusted resources and services to help you navigate the journey from premed to residency and beyond.

  • Administrators
  • MD-PhD Program Interview Committee
  • MSTP Faculty
  • MSTP Faculty by Discipline
  • Current Students
  • MD-PhD Advisory Committee
  • Student Council
  • Students Perspectives on, Inclusion, Diversity and Equity at Yale (SPIDEY)
  • Peer Advising by Senior Students (PASS)
  • Mentoring and Peer Advice from Recent Trainees (MPART)
  • Faculty Mentoring
  • Career Development
  • Useful Links
  • Parental Support and Relief
  • MD-PhD House System
  • Important Dates & Deadlines
  • Application Process
  • Financial Support
  • Life at Yale
  • Frequently Asked Questions
  • Who we are: Goals & Committees
  • What We Do: Current D&I Initiatives
  • Resources for Support
  • Resources for Self-Education
  • Yale BioMed Amgen Scholars Program
  • MD-PhD Timeline
  • Responsible Conduct of Research (RCR)
  • Clinical Activities
  • Research Activities
  • Leadership & Research Management Certificate
  • Annual Program Retreat
  • Perspectives of Women in Science Lectures
  • Grant-writing workshops
  • Teaching Requirements & Opportunities
  • Thriving in the Training Environment
  • Where To Go For Help
  • Physician-Scientist Specialty Shadowing Opportunities
  • 2019 Newsletters
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  • Residency Matches
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  • PhDs Conferred
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INFORMATION FOR

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MD-PhD Program

Our mission.

Our mission is to provide students with integrated training in clinical medicine and research that qualifies them to perform at the highest standards as rigorous clinicians and scientists; to create a diverse and inclusive physician-scientist community to support and mentor trainees along axes of personal identity, clinical discipline and research domain; to cultivate the characteristics of curiosity, creativity, compassion and service in our trainees; and to develop skills associated with success in a broad range of physician-scientist research careers through experiential learning.

Our commitment to diversity & inclusion

Director's welcome: yale md-phd program, message from the director.

Whether you are a prospective or current student, alumnus, faculty or staff member, you are here because of a shared interest in how physician-scientists can advance patient care through their unique and rigorous training in both clinical medicine and research.

Here at Yale, we have world-class scientists and clinicians engaged in basic, translational and clinical research that runs from sub-atomic bonds to the bonds that hold society together, and everything in between. Our students come from diverse backgrounds, with different scientific and clinical interests, but share the desire to make an impact through their work and practice. Our program has didactic, clinical and research opportunities within divisions, departments and schools that span the entire University. I am glad to report that the Yale System still lives and continues to promote a culture of independence of thought, creativity, mission and service among our collaborative students and faculty. I am very proud of our past and current students who do groundbreaking research that leads to advances in medicine.

I hope you take a moment to learn more about our program from these web pages, or by contacting any of our students, faculty or staff. If you are a student who is ready to accept the challenges, responsibilities and rewards of preparing for a career that makes a positive impact on human health and well-being, I invite you to apply to our MD-PhD program. We hope that you will become part of the Yale MD-PhD family, and join us in celebrating our 50th anniversary in 2020!

With warm regards,

Barbara Kazmierczak, MD PhD Professor of Medicine & Microbial Pathogenesis Gustavus and Louise Pfeiffer Research Foundation MD-PhD Program Director

Is an MD/PhD Program Right for You?

MD-PhD programs may be right for you if you are interested in a career path that melds both clinical practice and in-depth scientific research. MD-PhD graduates aren’t simply doctors; they are “physician-scientists” or “medical scientists.”

MD-PhD programs offer a dual-degree track that combines the clinical training of a standard MD degree with the added coursework of a PhD. The PhD training is particularly rigorous and includes classes usually in the realm of biomedical sciences, as well as advanced research training, lab rotations, and intensive investigative work.

The payoff for choosing an MD-PhD program is that these clinical medicine graduates are equipped to treat patients while also participating in the discovery and development of innovative healthcare solutions. 

Here are a few reasons you might want to pursue an MD/PhD career:

  • You want to participate in cutting-edge medical research.
  • You want career options beyond clinical medical practice.
  • You want to help train future generations of medical doctors.
  • You want more collaborative research opportunities with colleagues.
  • You want funding opportunities only available to MD/PhD students.

The Difference Between MD & MD/PhD

The difference between MD and MD-PhD is that graduates with an MD-PhD receive PhD training and hold a PhD degree in addition to their MD degree.

The cost of an MD-PhD program varies widely depending on the institution. Still, the stipend and tuition-free training make many of these programs significantly less financially burdensome compared to standalone MD or PhD programs.

MD/PhD students will complete graduate school and medical school qualified to hold positions in academic medicine and biomedical research (in addition to being qualified to practice clinical medicine. 

What Is an MD?

A medical doctor has earned a standard medical degree or MD and is skilled to practice clinical medicine. Medical students must complete 4 years of medical school to earn their degree, followed by 3-7 years of residency and fellowship training to practice medicine.

What Is a PhD?

PhD stands for Doctor of Philosophy in reference to their critical knowledge and research experience in a particular field of study. A PhD is the highest possible academic degree.

Earning a PhD is often considered harder than earning an MD due to the scientific research required to stimulate original thought and develop quality hypotheses.

How Competitive Are MD/PhD Programs?

Physician-scientist programs are slightly more selective and competitive than the average medical program.

Between 2018 and 2023, a little more than one-third of students who applied to an MD/PhD program (37.7%) were accepted. The acceptance rate for medical school applicants in general was 41.2% for the 2022-23 application cycle.

The test scores of these programs also indicate how much more competitive these programs are. The average MCAT score of MD/PhD matriculants in the 2022-23 cycle was 516.2, and their mean GPA was 3.82. In comparison, medical school matriculants overall had an average MCAT score of 511.9 and average GPA of 3.75 during the same cycle.

How Long Are MD/PhD Programs?

The MD-PhD dual degree takes approximately 7-8 years of coursework to complete, followed by an additional 3-7 years of residency to be eligible to practice medicine. 

Generally, MD coursework is emphasized in years 1-2, followed by research training in years 3-5, and ending with medical training and clinicals in years 6-8. 

Requirements for MD/PhD Applicants

If you are considering applying to an MD/PhD program , know that having strong essays and letters is more important than incrementally higher MCAT test scores and GPAs. Numbers get your foot in the door; storytelling gets you a seat at the table. 

In general, the requirements for MD/PhD applicants include:

  • MCAT score in the 90th percentile: Specific MCAT requirements for MD/PhD programs vary by school. However, in general, most students have the best chance at success with an MCAT score in the 90th percentile or higher. In the 2022-23 application cycle, MD/PhD applicants had an average MCAT score of 511.3, while matriculants averaged 516.2.
  • GPA of 3.7 or higher: Like MCAT scores, the GPA requirements for MD/PhD programs differ by program. But your chances are highest with an average GPA of at least 3.7. In the 2022-23 application cycle, MD/PhD applicants averaged a science GPA of 3.61 and overall GPA of 3.68, while matriculants averaged a 3.78 science GPA and 3.82 overall.
  • Compelling personal statement: Your personal statement essay should explain why you want to become a physician and is required for both MD & MD/PhD applications . All prospective doctors must write a personal statement that stands out, and this is doubly true for MD/PhD applicants.
  • 2 additional essays: You’ll write one essay conveying your personal interest in pursuing an MD/PhD dual degree specifically, and one essay covering your substantive experiences in the field of research . These may include multiple summer projects, senior thesis research, or 1+ years of post-undergrad research programs and activities.
  • 2-3 letters from research mentors who can praise your scientific potential.
  • 1-2 letters from clinical mentors who know your aptitude for patient care.
  • 1 letter from the premed committee.
  • 1 letter from a mentor who can discuss your leadership skills and personal traits in an extracurricular setting.

Questions to Ask Yourself When Considering an MD/PhD Program

By answering these questions, you can choose the graduate program that is the best fit for you over the next 8 years.

  • What skills do you want to develop? Choose a program that has ample opportunities to explore your field of interest and in which you can identify potential mentors for rotations and thesis projects.
  • What is your preferred MD/PhD program size? Choose a smaller program of MD-PhD students if you prefer hands-on guidance with individualized attention and a larger program if you prefer a larger community with more networking opportunities. 
  • Where do you want to live for 8 years of medical school ? Choose a location that fits your needs for cost of living, housing, transportation, extracurriculars, as well as opportunities for fun and making friends. 
  • Does the program offer financial aid? Choose a program that meets your financial needs in the form of stipends and tuition waivers. It’s important to note that if you drop out of an MD-PhD program, some schools require you to pay back the investment that the school made in you. 
  • Will you fit into the school’s culture? Choose a program after you’ve visited the campus, talked with the current students and faculty, and asked about opportunities in your field of interest as well as other’s experiences at the school and living in the city.
  • Does the MD/PhD Program align with your timeline? Choose a program with coursework that allows you to graduate in your preferred timeline, which could be sooner or longer than eight years.

Possible Career Paths for MD/PhD Graduates

A career choice often depends on an individual’s specific interests, such as which medical specialties they are drawn to, whether they prefer working with patients or in a laboratory, and how they want to contribute to advancing medical science.

The salary range for MD/PhD graduates varies significantly by position and type of work. Policy analysts’ starting salary is around $57,000 per year, while attending physicians who do research can make upwards of $500,000.

Below are careers someone with an MD-PhD might pursue:

Attending Physician with Research Responsibilities

An MD/PhD holder in this position would have a traditional medical role seeing and treating patients, but they might also have dedicated time for research. This role allows one to continue practicing medicine while contributing to academic or clinical research. 

Individuals in this role often split their time among patient care, research activities, and instructional duties. Typically, they are found in educational hospitals or medical schools.

Physicians’ salaries can vary significantly based on specialty and experience, but generally, they are well-compensated. An attending physician in a specialized field can expect to earn upwards of $200,000 to $500,000 or more, especially if they have dual responsibilities that include research.

Translational Medicine Specialist

These specialists work at the intersection of basic research and patient care, focusing on turning research insights into practical medical applications. 

This role may exist within academia, industry, or clinical settings and is tailored for those who understand both the clinical and research aspects of medicine.

The salary for this role can also vary based on industry, location, and level of experience but would likely fall in the range of $150,000 to $250,000 or more.

Biomedical Researcher

Those with MD-PhD qualifications commonly secure jobs as researchers within biomedical science. Employment settings can range from academic institutions and drug companies to governmental agencies like the NIH.

Salaries for biomedical researchers typically fall somewhere between $85,000 and $104,000 per year.

Clinical Research Director

These are medical doctors responsible for overseeing clinical trials and research projects, usually within a hospital, academic institution, or pharmaceutical/biotech company. This role leverages both the clinical insights from an MD and the research methodology of a PhD.

Salaries can vary widely depending on the setting (academia, private industry, etc.) and geographic location. In general, a Clinical Research Director could expect to earn a six-figure salary, often ranging from around $150,000 to $250,000 or more per year.

Pharmaceutical/Biotech Industry Professional

A significant number of MD-PhDs join the pharmaceutical or biotech sectors. Responsibilities might include roles in the development of new medications, overseeing clinical trials, regulatory compliance, or managing medical affairs.

The average salary for this position will likely differ quite a bit depending on the exact role and company, but the average is generally between $125,000 and $133,00 per year.

Medical Director

In this capacity, a person is in charge of the medical elements of a healthcare facility or a specific department within a hospital. The role usually calls for expertise in both medical practice and research.

This position is likely to be one of the most lucrative of the MD/PhD field, with an average salary from $319,000 to $329,000 per year.

Science Policy Analyst/Advisor

Individuals in this role often find themselves in governmental or nonprofit settings, where they influence policy decisions related to scientific research and healthcare.

The typical salary for a science policy analyst starts at around $57,000 per year. Advisors have a slightly higher upper salary range and may make as much as $75,000.

Public Health Official

Some MD-PhDs opt for roles in the public sector where they focus on health concerns at a societal level. They may be employed by organizations such as the CDC or WHO.

In many cases, public health officials can expect to make a yearly salary of between $101,000 and $111,000.

Medical Science Liaison

This role typically serves as an intermediary between pharmaceutical enterprises and medical professionals. These liaisons disseminate information about new treatments and scientific advancements to doctors, researchers, and other medical stakeholders.

This role also typically commands a six-figure salary, usually ranging from approximately $100,000 to $200,000, depending on experience, location, and the hiring organization.

Medical Educator

Professors teach medical students, residents, and fellows in an academic setting while also conducting research. These doctors often have clinical responsibilities as well. An MD/PhD is especially well-suited for this role due to the dual focus on clinical care and research.

They may teach various medical subjects like pharmacology or genetics and actively participate in the educational goals of their institutions.

In academia, salaries can vary widely based on rank (Assistant Professor, Associate Professor, Full Professor), institution, and geographic location. Salaries may range from $100,000 to well over $200,000 for senior roles or those at prestigious institutions.

Best MD/PhD Programs in the US

There are 122 different American Universities that offer MD/PhD degree programs, according to the AAMC list of MD-PhD Programs by State . A further 13 Canadian programs also use the AMCAS application system.

Some MD-PhD programs in the United States are funded by the National Institutes of Health (NIH) through the Medical Scientist Training Program (MSTP). This means that students receive full tuition remission, health insurance, and a living stipend throughout their training.

Medical schools with fully funded MD-PhD programs :

  • Dartmouth University, Geisel School of Medicine
  • Duke University School of Medicine
  • Harvard/M.I.T MD-PhD Program, Harvard Medical School
  • John Hopkins University School of Medicine
  • Mayo Clinic College of Medicine & Science
  • University of Florida College of Medicine
  • University of Pennsylvania, Perelman School of Medicine
  • University of Southern California (USC), Keck School of Medicine
  • Yale University School of Medicine

Medical schools with the most MD-PhD spots historically: 

  • Raymond and Ruth Perelman School of Medicine at the University of Pennsylvania
  • University of Illinois College of Medicine
  • Weill Cornell Medical College
  • Washington University in St. Louis School of Medicine
  • Johns Hopkins University School of Medicine
  • Albert Einstein College of Medicine of Yeshiva University
  • University of California, Los Angeles David Geffen School of Medicine
  • University of Michigan Medical School
  • Columbia University College of Physicians and Surgeons 
  • University of Pittsburgh School of Medicine
  • Harvard Medical School
  • Case Western Reserve University School of Medicine
  • Northwestern University The Feinberg School of Medicine
  • Icahn School of Medicine at Mount Sinai
  • University of California, San Francisco, School of Medicine
  • Vanderbilt University School of Medicine
  • Ohio State University College of Medicine
  • University of Wisconsin School of Medicine and Public Health
  • New York University School of Medicine
  • Stanford University School of Medicine
  • Yale School of Medicine

Medical schools with MD/PhD programs that accept international students:

  • Emory University School of Medicine
  • Northwestern Feinberg School of Medicine
  • University of Pennsylvania Perelman School of Medicine
  • University of Southern California Keck School of Medicine/California Institute of Technology
  • University of Texas Southwestern Medical School
  • Washington University School of Medicine in St. Louis

The MD/PhD Application Process

The application process for MD-PhD programs is similar to that of typical MD programs. The two major differences are that you’ll designate yourself as an MD/PhD candidate on the AMCAS application, and you’ll submit 2 additional essays on that primary.

The Application Timeline

  • AMCAS (submit by end of May): You’ll fill out a primary application through AMCAS in the spring of the first year of your application cycle (e.g., to matriculate in fall 2026, you’ll submit AMCAS in spring 2025). AMCAS opens at the end of May each year. Aim to submit the primary application no later than the end of June, as early applications are more likely to be reviewed and accepted.
  • Secondaries (submit by end of August): You’ll respond to secondary applications in the summer after your primary application is reviewed by each school you submitted it to. Each program sends secondary applications to students who generally meet their minimum requirements.
  • Interviews (October-March): You’ll then attend interviews as invited between October and March. Some schools won’t contact you at all to reject your application; others will offer conflicting invites. You must prioritize your options and prepare for the opportunities that do come. 
  • Final decisions (December-March): Final decisions are made by schools between December and March. Schools with a rolling admissions cycle (most of them) accept students after completing interviews and determining a student is a fit. A smaller number of programs wait to send acceptances until after all interviews are complete.
  • Choose your program (March-April): Students choose where to matriculate between March and April.
  • Programs start (June-August): Programs begin between June and August, depending on the school.

How to Prepare for an MD/PhD interview

You should prepare for your MD/PhD interview by practicing mock interviews to rid yourself of the jitters and fine-tune your responses in various scenarios. In addition to developing your personal narrative, you must be able to explain your research training at multiple levels.  

If you’re interested in participating in a mock interview with a physician who has served on an admissions committee, consider a mock interview with MedSchoolCoach .

What to Do if You Get Waitlisted

Finding out that you’ve been waitlisted for the MD/PhD program of your dreams is never a good feeling. However, you are not helpless in the wait. It’s a good idea to remain in contact with program leaders and administrators by sending a Letter of Intent or a Letter of Interest.

Listen: An MD/PHD’s Journey to Medicine [PODCAST]  

What is a Letter of Intent vs. a Letter of Interest? 

A Letter of Intent is a formal statement that you would commit to matriculating into a program if you are accepted. A Letter of Interest conveys that you are strongly interested in the program, but it does not indicate any commitment or explicitly state that a program is your first choice.

Both letters should summarize why you believe the program and school are a great fit for your interests and how you will be able to uniquely contribute to the school, in under one page.

Finding Out You’ve Been Accepted!

The day you receive that phone call or email — the one from the MD-PhD program director contacting you to say you have officially been offered acceptance into their program — provides a feeling of joy worth being patient for!

Our Physician Advisors can support you through the application process for your best shot at getting into the school of your choice.

What specialties can MD/PhD graduates earn their PhD in?  

PhD students commonly choose to specialize in topics such as:

  • Cell Biology
  • Biochemistry
  • Pharmacology
  • Neuroscience
  • Biomedical Engineering

What is the salary range for an MD/PhD graduate? 

MD/PhD graduates can expect an average annual salary of about $100K, depending on the type of work and place of employment.

What is the difference between a PhD and a Postdoctorate? 

A Postdoctoral Fellowship is a temporary period of mentorship and research training for graduates with doctoral degrees, offered by the National Institutes of Health, to acquire skills needed for a chosen career. A PhD thesis must be successfully defended, whereas a postdoc is a non-defendable temporary employment assignment from an organization such as a university.

Can an MD/PhD be a doctor? 

Graduates who earn an MD/PhD are fully qualified doctors and may practice medicine in a clinical setting upon completing their residency training.

Can an MD/PhD graduate be a surgeon? 

While an MD/PhD graduate CAN be a surgeon if they choose surgery specialties in their residency programs, a surgical resident is not required to obtain a PhD in addition to their MD.

Schedule a free 15-minute consultation with MedSchoolCoach to learn how we can help boost your chances of success getting into medical school .

Related posts:

  • How to Write About COVID-19 in Your Medical School Personal Statement
  • Use MSAR To Choose Which Medical Schools You’ll Apply To
  • 5 Reasons to Consider a Pre-Med Traveling doctor program(+ Tips for Traveling!)
  • What Counts as Clinical Experience for Medical School?

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