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Published by Robert Bruce at August 29th, 2023 , Revised On September 5, 2023

Biology Research Topics

Are you in need of captivating and achievable research topics within the field of biology? Your quest for the best biology topics ends right here as this article furnishes you with 100 distinctive and original concepts for biology research, laying the groundwork for your research endeavor.

Table of Contents

Our proficient researchers have thoughtfully curated these biology research themes, considering the substantial body of literature accessible and the prevailing gaps in research.

Should none of these topics elicit enthusiasm, our specialists are equally capable of proposing tailor-made research ideas in biology, finely tuned to cater to your requirements. 

Thus, without further delay, we present our compilation of biology research topics crafted to accommodate students and researchers.

Research Topics in Marine Biology

  • Impact of climate change on coral reef ecosystems.
  • Biodiversity and adaptation of deep-sea organisms.
  • Effects of pollution on marine life and ecosystems.
  • Role of marine protected areas in conserving biodiversity.
  • Microplastics in marine environments: sources, impacts, and mitigation.

Biological Anthropology Research Topics

  • Evolutionary implications of early human migration patterns.
  • Genetic and environmental factors influencing human height variation.
  • Cultural evolution and its impact on human societies.
  • Paleoanthropological insights into human dietary adaptations.
  • Genetic diversity and population history of indigenous communities.

Biological Psychology Research Topics 

  • Neurobiological basis of addiction and its treatment.
  • Impact of stress on brain structure and function.
  • Genetic and environmental influences on mental health disorders.
  • Neural mechanisms underlying emotions and emotional regulation.
  • Role of the gut-brain axis in psychological well-being.

Cancer Biology Research Topics 

  • Targeted therapies in precision cancer medicine.
  • Tumor microenvironment and its influence on cancer progression.
  • Epigenetic modifications in cancer development and therapy.
  • Immune checkpoint inhibitors and their role in cancer immunotherapy.
  • Early detection and diagnosis strategies for various types of cancer.

Also read: Cancer research topics

Cell Biology Research Topics

  • Mechanisms of autophagy and its implications in health and disease.
  • Intracellular transport and organelle dynamics in cell function.
  • Role of cell signaling pathways in cellular response to external stimuli.
  • Cell cycle regulation and its relevance to cancer development.
  • Cellular mechanisms of apoptosis and programmed cell death.

Developmental Biology Research Topics 

  • Genetic and molecular basis of limb development in vertebrates.
  • Evolution of embryonic development and its impact on morphological diversity.
  • Stem cell therapy and regenerative medicine approaches.
  • Mechanisms of organogenesis and tissue regeneration in animals.
  • Role of non-coding RNAs in developmental processes.

Also read: Education research topics

Human Biology Research Topics

  • Genetic factors influencing susceptibility to infectious diseases.
  • Human microbiome and its impact on health and disease.
  • Genetic basis of rare and common human diseases.
  • Genetic and environmental factors contributing to aging.
  • Impact of lifestyle and diet on human health and longevity.

Molecular Biology Research Topics 

  • CRISPR-Cas gene editing technology and its applications.
  • Non-coding RNAs as regulators of gene expression.
  • Role of epigenetics in gene regulation and disease.
  • Mechanisms of DNA repair and genome stability.
  • Molecular basis of cellular metabolism and energy production.

Research Topics in Biology for Undergraduates

  • 41. Investigating the effects of pollutants on local plant species.
  • Microbial diversity and ecosystem functioning in a specific habitat.
  • Understanding the genetics of antibiotic resistance in bacteria.
  • Impact of urbanization on bird populations and biodiversity.
  • Investigating the role of pheromones in insect communication.

Synthetic Biology Research Topics 

  • Design and construction of synthetic biological circuits.
  • Synthetic biology applications in biofuel production.
  • Ethical considerations in synthetic biology research and applications.
  • Synthetic biology approaches to engineering novel enzymes.
  • Creating synthetic organisms with modified functions and capabilities.

Animal Biology Research Topics 

  • Evolution of mating behaviors in animal species.
  • Genetic basis of color variation in butterfly wings.
  • Impact of habitat fragmentation on amphibian populations.
  • Behavior and communication in social insect colonies.
  • Adaptations of marine mammals to aquatic environments.

Also read: Nursing research topics

Best Biology Research Topics 

  • Unraveling the mysteries of circadian rhythms in organisms.
  • Investigating the ecological significance of cryptic coloration.
  • Evolution of venomous animals and their prey.
  • The role of endosymbiosis in the evolution of eukaryotic cells.
  • Exploring the potential of extremophiles in biotechnology.

Biological Psychology Research Paper Topics

  • Neurobiological mechanisms underlying memory formation.
  • Impact of sleep disorders on cognitive function and mental health.
  • Biological basis of personality traits and behavior.
  • Neural correlates of emotions and emotional disorders.
  • Role of neuroplasticity in brain recovery after injury.

Biological Science Research Topics: 

  • Role of gut microbiota in immune system development.
  • Molecular mechanisms of gene regulation during development.
  • Impact of climate change on insect population dynamics.
  • Genetic basis of neurodegenerative diseases like Alzheimer’s.
  • Evolutionary relationships among vertebrate species based on DNA analysis.

Biology Education Research Topics 

  • Effectiveness of inquiry-based learning in biology classrooms.
  • Assessing the impact of virtual labs on student understanding of biology concepts.
  • Gender disparities in science education and strategies for closing the gap.
  • Role of outdoor education in enhancing students’ ecological awareness.
  • Integrating technology in biology education: challenges and opportunities.

Biology-Related Research Topics

  • The intersection of ecology and economics in conservation planning.
  • Molecular basis of antibiotic resistance in pathogenic bacteria.
  • Implications of genetic modification of crops for food security.
  • Evolutionary perspectives on cooperation and altruism in animal behavior.
  • Environmental impacts of genetically modified organisms (GMOs).

Biology Research Proposal Topics

  • Investigating the role of microRNAs in cancer progression.
  • Exploring the effects of pollution on aquatic biodiversity.
  • Developing a gene therapy approach for a genetic disorder.
  • Assessing the potential of natural compounds as anti-inflammatory agents.
  • Studying the molecular basis of cellular senescence and aging.

Biology Research Topic Ideas

  • Role of pheromones in insect mate selection and behavior.
  • Investigating the molecular basis of neurodevelopmental disorders.
  • Impact of climate change on plant-pollinator interactions.
  • Genetic diversity and conservation of endangered species.
  • Evolutionary patterns in mimicry and camouflage in organisms.

Biology Research Topics for Undergraduates 

  • Effects of different fertilizers on plant growth and soil health.
  • Investigating the biodiversity of a local freshwater ecosystem.
  • Evolutionary origins of a specific animal adaptation.
  • Genetic diversity and disease susceptibility in human populations.
  • Role of specific genes in regulating the immune response.

Cell and Molecular Biology Research Topics 

  • Molecular mechanisms of DNA replication and repair.
  • Role of microRNAs in post-transcriptional gene regulation.
  • Investigating the cell cycle and its control mechanisms.
  • Molecular basis of mitochondrial diseases and therapies.
  • Cellular responses to oxidative stress and their implications in ageing.

These topics cover a broad range of subjects within biology, offering plenty of options for research projects. Remember that you can further refine these topics based on your specific interests and research goals.

Frequently Asked Questions 

What are some good research topics in biology?

A good research topic in biology will address a specific problem in any of the several areas of biology, such as marine biology, molecular biology, cellular biology, animal biology, or cancer biology.

A topic that enables you to investigate a problem in any area of biology will help you make a meaningful contribution. 

How to choose a research topic in biology?

Choosing a research topic in biology is simple. 

Follow the steps:

  • Generate potential topics. 
  • Consider your areas of knowledge and personal passions. 
  • Conduct a thorough review of existing literature.
  •  Evaluate the practicality and viability. 
  • Narrow down and refine your research query. 
  • Remain receptive to new ideas and suggestions.

Who Are We?

For several years, Research Prospect has been offering students around the globe complimentary research topic suggestions. We aim to assist students in choosing a research topic that is both suitable and feasible for their project, leading to the attainment of their desired grades. Explore how our services, including research proposal writing , dissertation outline creation, and comprehensive thesis writing , can contribute to your college’s success.

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200+ Unique And Interesting Biology Research Topics For Students In 2023

Biology Research Topics

Are you curious about the fascinating world of biology and its many research possibilities? Well, you are in the right place! In this blog, we will explore biology research topics, exploring what biology is, what constitutes a good research topic, and how to go about selecting the perfect one for your academic journey.

So, what exactly is biology? Biology is the study of living organisms and their interactions with the environment. It includes everything from the tiniest cells to the largest ecosystems, making it a diverse and exciting field of study.

Stay tuned to learn more about biology research topics as we present over 200 intriguing research ideas for students, emphasizing the importance of selecting the right one. In addition, we will also share resources to make your quest for the perfect topic a breeze. Let’s embark on this scientific journey together!

If you are having trouble with any kind of assignment or task, do not worry—we can give you the best microbiology assignment help at a value price. Additionally, you may look at nursing project ideas .

What Is Biology?

Table of Contents

Biology is the study of living things, like animals, plants, and even tiny organisms too small to see. It helps us understand how these living things work and how they interact with each other and their environment. Biologists, or scientists who study biology, explore topics like how animals breathe, how plants grow, and how our bodies function. By learning about biology, we can better care for the Earth and all its living creatures.

What Is A Good Biology Research Topic?

A good biology research topic is a question or problem in the field of biology that scientists want to investigate and learn more about. It should be interesting and important, like studying how a new medicine can treat a disease or how animals adapt to changing environments. The topic should also be specific and clear, so researchers can focus on finding answers. Additionally, it’s helpful if the topic hasn’t been studied extensively before, so the research can contribute new knowledge to the field of biology and help us better understand the natural world.

Tips For Choosing A Biology Research Topics

Here are some tips for choosing a biology research topics:

1. Choose What Interests You

When picking a biology research topic, go for something that you personally find fascinating and enjoyable. When you’re genuinely curious about it, you’ll be more motivated to study and learn.

2. Select a Significant Topic

Look for a subject in biology that has real-world importance. Think about whether your research can address practical issues, like finding cures for diseases or understanding environmental problems. Research that can make a positive impact is usually a good choice.

3. Check If It’s Doable

Consider if you have the necessary tools and time to carry out your research. It’s essential to pick a topic that you can actually study with the resources available to you.

4. Add Your Unique Perspective

Try to find a fresh or different angle for your research. While you can build upon existing knowledge, bringing something new or unique to the table can make your research more exciting and valuable.

5. Seek Guidance

Don’t hesitate to ask for advice from your teachers or experienced researchers. They can provide you with valuable insights and help you make a smart decision when choosing your research topic in biology.

Biology Research Topics For College Students

1. Investigating the role of genetic mutations in cancer development.

2. Analyzing the impact of climate changes on wildlife populations.

3. Studying the ecology of invasive species in urban environments.

4. Investigating the microbiome of the human gut and its relationship to health.

5. Analyzing the genetic diversity of endangered species for conservation.

6. Studying the evolution of antibiotic resistance in bacteria.

7. Investigating the ecological consequences of deforestation.

8. Analyzing the behavior and communication of social insects like ants and bees.

9. Studying the physiology of extreme environments, such as deep-sea hydrothermal vents.

10. Investigating the molecular mechanisms of cell division and mitosis.

Plant Biology Research Topics For College Students

11. Studying the impact of different fertilizers on crop yields and soil health.

12. Analyzing the genetics of plant resistance to pests and diseases.

13. Investigating the role of plant hormones in growth and development.

14. Studying the adaptation of plants to drought conditions.

15. Analyzing the ecological interactions between plants and pollinators.

16. Investigating the use of biotechnology to enhance crop traits.

17. Studying the genetics of plant breeding for improved varieties.

18. Analyzing the physiology of photosynthesis and carbon fixation in plants.

19. Investigating the effects of soil microbiota on plant health.

20. Studying the evolution of plant species in response to changing environments.

Biotechnology Research Topics For College Students

21. Investigating the use of CRISPR-Cas9 technology for genome editing.

22. Analyzing the production of biofuels from microorganisms.

23. Studying the application of biotechnology in medicine, such as gene therapy.

24. Investigating the use of bioplastics as a sustainable alternative to conventional plastics.

25. Analyzing the role of biotechnology in food production, including GMOs.

26. Studying the development of biopharmaceuticals and monoclonal antibodies.

27. Investigating the use of bioremediation to clean up polluted environments.

28. Studying the potential of synthetic biology for creating novel organisms.

29. Analyzing the ethical and social implications of biotechnological advancements.

30. Investigating the use of biotechnology in forensic science, such as DNA analysis.

Molecular Biology Research Topics For Undergraduates

31. Studying the structure and function of DNA and RNA molecules.

32. Analyzing the regulation of gene expression in eukaryotic cells.

33. Investigating the mechanisms of DNA replication and repair.

34. Studying the role of non-coding RNAs in gene regulation.

35. Analyzing the molecular basis of genetic diseases like cystic fibrosis.

36. Investigating the epigenetic modifications that control gene activity.

37. Studying the molecular mechanisms of protein folding and misfolding.

38. Analyzing the molecular pathways involved in cancer progression.

39. Investigating the molecular basis of neurodegenerative diseases.

40. Studying the use of molecular markers in genetic diversity analysis.

Life Science Research Topics For High School Students

41. Investigating the effects of different diets on human health.

42. Analyzing the impact of exercise on cardiovascular fitness.

43. Studying the genetics of inherited traits and diseases.

44. Investigating the ecological interactions in a local ecosystem.

45. Analyzing the diversity of microorganisms in soil or water samples.

46. Studying the anatomy and physiology of a specific organ or system.

47. Investigating the life cycle of a local plant or animal species.

48. Studying the effects of environmental pollutants on aquatic organisms.

49. Analyzing the behavior of a specific animal species in its habitat.

50. Investigating the process of photosynthesis in plants.

Biology Research Topics For Grade 12

51. Investigating the genetic basis of a specific inherited disorder.

52. Analyzing the impact of climate change on a local ecosystem.

53.Studying the biodiversity of a particular rainforest region.

54. Investigating the physiological adaptations of animals to extreme temperatures.

55. Analyzing the effects of pollution on aquatic ecosystems.

56. Studying the life history and conservation status of an endangered species.

57. Investigating the molecular mechanisms of a specific disease.

58. Studying the ecological interactions within a coral reef ecosystem.

59. Analyzing the genetics of plant hybridization and speciation.

60. Investigating the behavior and communication of a particular bird species.

Marine Biology Research Topics

61. Studying the impact of ocean acidification on coral reefs.

62. Analyzing the migration patterns of marine mammals.

63. Investigating the physiology of deep-sea creatures under high pressure.

64. Studying the ecology of phytoplankton and their role in the marine food web.

65. Analyzing the behavior of different species of sharks.

66. Investigating the conservation of sea turtle populations.

67. Studying the biodiversity of deep-sea hydrothermal vent communities.

68. Analyzing the effects of overfishing on marine ecosystems.

69. Investigating the adaptation of marine organisms to extreme cold in polar regions.

70. Studying the bioluminescence and communication in marine organisms.

AP Biology Research Topics

71. Investigating the role of specific enzymes in cellular metabolism.

72. Analyzing the genetic variation within a population.

73. Studying the mechanisms of hormonal regulation in animals.

74. Investigating the principles of Mendelian genetics through trait analysis.

75. Analyzing the ecological succession in a local ecosystem.

76. Studying the physiology of the human circulatory system.

77. Investigating the molecular biology of a specific virus.

78. Studying the principles of natural selection through evolutionary simulations.

79. Analyzing the genetic diversity of a plant species in different habitats.

80. Investigating the effects of different environmental factors on plant growth.

Cell Biology Research Topics

81. Investigating the role of mitochondria in cellular energy production.

82. Analyzing the mechanisms of cell division and mitosis.

83. Studying the function of cell membrane proteins in signal transduction.

84. Investigating the cellular processes involved in apoptosis (cell death).

85. Analyzing the role of endoplasmic reticulum in protein synthesis and folding.

86. Studying the dynamics of the cytoskeleton and cell motility.

87. Investigating the regulation of cell cycle checkpoints.

88. Analyzing the structure and function of cellular organelles.

89. Studying the molecular mechanisms of DNA replication and repair.

90. Investigating the impact of cellular stress on cell health and function.

Human Biology Research Topics

91. Analyzing the genetic basis of inherited diseases in humans.

92. Investigating the physiological responses to exercise and physical activity.

93. Studying the hormonal regulation of the human reproductive system.

94. Analyzing the impact of nutrition on human health and metabolism.

95. Investigating the role of the immune system in disease prevention.

96. Studying the genetics of human evolution and migration.

97. Analyzing the neural mechanisms underlying human cognition and behavior.

98. Investigating the molecular basis of aging and age-related diseases.

99. Studying the impact of environmental toxins on human health.

100. Analyzing the genetics of organ transplantation and tissue compatibility.

Molecular Biology Research Topics

101. Investigating the role of microRNAs in gene regulation.

102. Analyzing the molecular basis of genetic disorders like cystic fibrosis.

103. Studying the epigenetic modifications that control gene expression.

104. Investigating the molecular mechanisms of RNA splicing.

105. Analyzing the role of telomeres in cellular aging.

106. Studying the molecular pathways involved in cancer metastasis.

107. Investigating the molecular basis of neurodegenerative diseases.

108. Studying the molecular interactions in protein-protein networks.

109. Analyzing the molecular mechanisms of DNA damage and repair.

110. Investigating the use of CRISPR-Cas9 for genome editing.

Animal Biology Research Topics

111. Studying the behavior and communication of social insects like ants.

112. Analyzing the physiology of hibernation in mammals.

113. Investigating the ecological interactions in a predator-prey relationship.

114. Studying the adaptations of animals to extreme environments.

115. Analyzing the genetics of inherited traits in animal populations.

116. Investigating the impact of climate change on animal migration patterns.

117. Studying the diversity of marine life in coral reef ecosystems.

118. Analyzing the physiology of flight in birds and bats.

119. Investigating the molecular basis of animal coloration and camouflage.

120. Studying the behavior and conservation of endangered species.

  • Neuroscience Research Topics
  • Mental Health Research Topics

Plant Biology Research Topics

121. Investigating the role of plant hormones in growth and development.

122. Analyzing the genetics of plant resistance to pests and diseases.

123. Climate change and plant phenology are being examined.

124. Investigating the ecology of mycorrhizal fungi and their symbiosis with plants.

125. Investigating plant photosynthesis and carbon fixing.

126. Molecular analysis of plant stress responses.

127. Investigating the adaptation of plants to drought conditions.

128. Studying the role of plants in phytoremediation of polluted environments.

129. Analyzing the genetics of plant hybridization and speciation.

130. Investigating the molecular basis of plant-microbe interactions.

Environmental Biology Research Topics

131. Analyzing the effects of pollution on aquatic ecosystems.

132. Investigating the biodiversity of a particular ecosystem.

133. Studying the ecological consequences of deforestation.

134. Analyzing the impact of climate change on wildlife populations.

135. Investigating the use of bioremediation to clean up polluted sites.

136. Studying the environmental factors influencing species distribution.

137. Analyzing the effects of habitat fragmentation on wildlife.

138. Investigating the ecology of invasive species in new environments.

139. Studying the conservation of endangered species and habitats.

140. Analyzing the interactions between humans and urban ecosystems.

Chemical Biology Research Topics

141. Investigating the design and synthesis of new drug compounds.

142. Analyzing the molecular mechanisms of enzyme catalysis.

143.Studying the role of small molecules in cellular signaling pathways.

144. Investigating the development of chemical probes for biological research.

145. Studying the chemistry of protein-ligand interactions.

146. Analyzing the use of chemical biology in cancer therapy.

147. Investigating the synthesis of bioactive natural products.

148. Studying the role of chemical compounds in microbial interactions.

149. Analyzing the chemistry of DNA-protein interactions.

150. Investigating the chemical basis of drug resistance in pathogens.

Medical Biology Research Topics

151. Investigating the genetic basis of specific diseases like diabetes.

152. Analyzing the mechanisms of drug resistance in bacteria.

153. Studying the molecular mechanisms of autoimmune diseases.

154. Investigating the development of personalized medicine approaches.

155. Studying the role of inflammation in chronic diseases.

156. Analyzing the genetics of rare diseases and genetic syndromes.

157. Investigating the molecular basis of viral infections and vaccines.

158. Studying the mechanisms of organ transplantation and rejection.

159. Analyzing the molecular diagnostics of cancer.

160. Investigating the biology of stem cells and regenerative medicine.

Evolutionary Biology Research Topics

161. Studying the evolution of human ancestors and early hominids.

162. The genetic variety of species and between species is being looked at.

163. Investigating the role of sexual selection in animal evolution.

164. Studying the co-evolutionary relationships between parasites and hosts.

165. Analyzing the evolutionary adaptations of extremophiles.

166. Investigating the evolution of developmental processes (evo-devo).

167. Studying the biogeography and distribution of species.

168. Analyzing the evolution of mimicry in animals and plants.

169. Investigating the genetics of speciation and hybridization.

170. Studying the evolutionary history of domesticated plants and animals.

Cellular Biology Research Topics

171. Investigating the role of autophagy in cellular homeostasis.

172. Analyzing the mechanisms of cellular transport and trafficking.

173. Studying the regulation of cell adhesion & migration.

174. Investigating the cellular responses to DNA damage.

175. Analyzing the dynamics of cellular membrane structures.

176. Studying the role of cellular organelles in lipid metabolism.

177. Investigating the molecular mechanisms of cell-cell communication.

178. Studying the physiology of cellular respiration and energy production.

179. Analyzing the cellular mechanisms of viral entry and replication.

180. Investigating the role of cellular senescence in aging and disease.

Good Biology Research Topics Related To Brain Injuries

181. Analyzing the molecular mechanisms of traumatic brain injury.

182. Investigating the role of neuroinflammation in brain injury recovery.

183. Studying the impact of concussions on long-term brain health.

184. Analyzing the use of neuroimaging in diagnosing brain injuries.

185. Investigating the development of neuroprotective therapies.

186. Studying the genetics of susceptibility to brain injuries.

187. Analyzing the cognitive and behavioral effects of brain trauma.

188. Investigating the role of rehabilitation in brain injury recovery.

189. Studying the cellular and molecular changes in axonal injury.

190. Looking into how stem cell therapy might be used to help brain injuries.

Biology Quantitative Research Topics

191. Investigating the mathematical modeling of population dynamics.

192. Analyzing the statistical methods for biodiversity assessment.

193. Studying the use of bioinformatics in genomics research.

194. Investigating the quantitative analysis of gene expression data.

195. Studying the mathematical modeling of enzyme kinetics.

196. Analyzing the statistical approaches for epidemiological studies.

197. Investigating the use of computational tools in phylogenetics.

198. Studying the mathematical modeling of ecological systems.

199. Analyzing the quantitative analysis of protein-protein interactions.

200. Investigating the statistical methods for analyzing genetic variation.

Importance Of Choosing The Right Biology Research Topics

Here are some importance of choosing the right biology research topics: 

1. Relevance to Your Interests and Goals

Choosing the right biology research topic is important because it should align with your interests and goals. Studying something you’re passionate about keeps you motivated and dedicated to your research.

2. Contribution to Scientific Knowledge

Your research should contribute something valuable to the world of science. Picking the right topic means you have the chance to discover something new or solve a problem, advancing our understanding of the natural world.

3. Availability of Resources

Consider the resources you have or can access. If you pick a topic that demands resources you don’t have, your research may hit a dead end. Choosing wisely means you can work efficiently.

4. Feasibility and Manageability

A good research topic should be manageable within your time frame and capabilities. If it’s too broad or complex, you might get overwhelmed. Picking the right topic ensures your research is doable.

5. Real-World Impact

Think about how your research might benefit the real world. Biology often has implications for health, the environment, or society. Choosing a topic with practical applications can make your work meaningful and potentially change lives.

Resources For Finding Biology Research Topics

There are numerous resources for finding biology research topics:

1. Online Databases

Look on websites like PubMed and Google Scholar. They have lots of biology articles. Type words about what you like to find topics.

2. Academic Journals

Check biology magazines. They talk about new research. You can find ideas and see what’s important.

3. University Websites

Colleges show what their teachers study. Find teachers who like what you like. Ask them about ideas for your own study.

4. Science News and Magazines

Read science news. They tell you about new things in biology. It helps you think of research ideas.

5. Join Biology Forums and Communities

Talk to other people who like biology online. You can ask for ideas and find friends to help you. Use websites like ResearchGate and Reddit for this.

Conclusion 

Biology Research Topics offer exciting opportunities for exploration and learning. We’ve explained what biology is and stressed the importance of picking a good research topic. Our tips and extensive list of over 200 biology research topics provide valuable guidance for students.

Selecting the right topic is more than just getting good grades; it’s about making meaningful contributions to our understanding of life. We’ve also shared resources to help you discover even more topics. So, embrace the world of biology research, embark on a journey of discovery, and be part of the ongoing effort to unravel the mysteries of the natural world.

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49 Most Interesting Biology Research Topics

August 21, 2023

biology research topics

In need of the perfect biology research topics—ideas that can both showcase your intellect and fuel your academic success? Lost in the boundless landscape of possible biology topics to research? And afraid you’ll never get a chance to begin writing your paper, let alone finish writing? Whether you’re a budding biologist hoping for a challenge or a novice seeking easy biology research topics to wade into, this blog offers curated and comprehensible options.

And if you’re a high school or transfer student looking for opportunities to immerse yourself in biology, consider learning more about research opportunities for high school students , top summer programs for high school students , best colleges for studying biomedical engineering , and best colleges for studying biology .

What is biology?

Well, biology explores the web of life that envelops our planet, from the teeny-tiny microbes to the big complex ecosystems. Biology investigates the molecular processes that define existence, deciphers the interplay of genes, and examines all the dynamic ways organisms interact with their environments. And through biology, you can gain not only knowledge, but a deeper appreciation for the interconnectedness of all living things. Pretty cool!

There are lots and lots of sub-disciplines within biology, branching out in all directions. Throughout this list, we won’t follow all of those branches, but we will follow many. And while none of these branches are truly simple or easy, some might be easier than others. Now we’ll take a look at a few various biology research topics and example questions that could pique your curiosity.

Climate change and ecosystems

The first of our potentially easy biology research topics: climate change and ecosystems. Investigate how ecosystems respond and adapt to the changing climate. And learn about shifts in species distributions , phenology , and ecological interactions .

1) How are different ecosystems responding to temperature changes and altered precipitation patterns?2) What are the implications of shifts in species distributions for ecosystem stability and functioning?

2) Or how does phenology change in response to climate shifts? And how do those changes impact species interactions?

3) Which underlying genetic and physiological mechanisms enable certain species to adapt to changing climate conditions?

4) And how do changing climate conditions affect species’ abilities to interact and form mutualistic relationships within ecosystems?

Microbiome and human health

Intrigued by the relationship between the gut and the rest of the body? Study the complex microbiome . You could learn how gut microbes influence digestion, immunity, and even mental health.

5) How do specific gut microbial communities impact nutrient absorption?

6) What are the connections between the gut microbiome, immune system development, and susceptibility to autoimmune diseases?

7) What ethical considerations need to be addressed when developing personalized microbiome-based therapies? And how can these therapies be safely and equitably integrated into clinical practice?

8) Or how do variations in the gut microbiome contribute to mental health conditions such as anxiety and depression?

9) How do changes in diet and lifestyle affect the composition and function of the gut microbiome? And what are the subsequent health implications?

Urban biodiversity conservation

Next, here’s another one of the potentially easy biology research topics. Examine the challenges and strategies for conserving biodiversity in urban environments. Consider the impact of urbanization on native species and ecosystem services. Then investigate the decline of pollinators and its implications for food security or ecosystem health.

10) How does urbanization influence the abundance and diversity of native plant and animal species in cities?

11) Or what are effective strategies for creating and maintaining green spaces that support urban biodiversity and ecosystem services?

12) How do different urban design and planning approaches impact the distribution of wildlife species and their interactions?

13) What are the best practices for engaging urban communities in biodiversity conservation efforts?

14) And how can urban agriculture and rooftop gardens contribute to urban biodiversity conservation while also addressing food security challenges?

Bioengineering

Are you a problem solver at heart? Then try approaching the intersection of engineering, biology, and medicine. Delve into the field of synthetic biology , where researchers engineer biological systems to create novel organisms with useful applications.

15) How can synthetic biology be harnessed to develop new, sustainable sources of biofuels from engineered microorganisms?

16) And what ethical considerations arise when creating genetically modified organisms for bioremediation purposes?

17) Can synthetic biology techniques be used to design plants that are more efficient at withdrawing carbon dioxide from the atmosphere?

18) How can bioengineering create organisms capable of producing valuable pharmaceutical compounds in a controlled and sustainable manner?

19) But what are the potential risks and benefits of using engineered organisms for large-scale environmental cleanup projects?

Neurobiology

Interested in learning more about what makes creatures tick? Then this might be one of your favorite biology topics to research. Explore the neural mechanisms that underlie complex behaviors in animals and humans. Shed light on topics like decision-making, social interactions, and addiction. And investigate how brain plasticity and neurogenesis help the brain adapt to learning, injury, and aging.

20) How does the brain’s reward circuitry influence decision-making processes in situations involving risk and reward?

21) What neural mechanisms underlie empathy and social interactions in both humans and animals?

22) Or how do changes in neural plasticity contribute to age-related cognitive decline and neurodegenerative diseases?

23) Can insights from neurobiology inform the development of more effective treatments for addiction and substance abuse?

24) What are the neural correlates of learning and memory? And how can our understanding of these processes be applied to educational strategies?

Plant epigenomics

While this might not be one of the easy biology research topics, it will appeal to plant enthusiasts. Explore how epigenetic modifications in plants affect their ability to respond and adapt to changing environmental conditions.

25) How do epigenetic modifications influence the expression of stress-related genes in plants exposed to temperature fluctuations?

26) Or what role do epigenetic changes play in plants’ abilities to acclimate to changing levels of air pollution?

27) Can certain epigenetic modifications be used as indicators of a plant’s adaptability to new environments?

28) How do epigenetic modifications contribute to the transgenerational inheritance of traits related to stress resistance?

29) And can targeted manipulation of epigenetic marks enhance crop plants’ ability to withstand changing environmental conditions?

Conservation genomics

Motivated to save the planet? Conservation genomics stands at the forefront of modern biology, merging the power of genetics with the urgent need to protect Earth’s biodiversity. Study genetic diversity, population dynamics, and how endangered species adapt in response to environmental changes.

30) How does genetic diversity within endangered species influence their ability to adapt to changing environmental conditions?

31) What genetic factors contribute to the susceptibility of certain populations to diseases, and how can this knowledge inform conservation strategies?

32) How can genomic data be used to inform captive breeding and reintroduction programs for endangered species?

33) And what are the genomic signatures of adaptation in response to human-induced environmental changes, such as habitat fragmentation and pollution?

34) Or how can genomics help identify “hotspots” of biodiversity that are particularly important for conservation efforts?

Zoonotic disease transmission

And here’s one of the biology research topics that’s been on all our minds in recent years. Investigate the factors contributing to the transmission of zoonotic diseases , like COVID-19. Then posit strategies for prevention and early detection.

35) What are the ecological and genetic factors that facilitate the spillover of zoonotic pathogens from animals to humans?

36) Or how do changes in land use, deforestation, and urbanization impact the risk of zoonotic disease emergence?

37) Can early detection and surveillance systems be developed to predict and mitigate the spread of zoonotic diseases?

38) How do social and cultural factors influence human behaviors that contribute to zoonotic disease transmission?

39) And can strategies be implemented to improve global pandemic preparedness?

Bioinformatics

Are you a data fanatic? Bioinformatics involves developing computational tools and techniques to analyze and interpret large biological datasets. This enables advancements in genomics, proteomics, and systems biology. So delve into the world of bioinformatics to learn how large-scale genomic and molecular data are revolutionizing biological research.

40) How can machine learning algorithms predict the function of genes based on their DNA sequences?

41) And what computational methods can identify potential drug targets by analyzing protein-protein interactions in large biological datasets?

42) Can bioinformatics tools be used to identify potential disease-causing mutations in human genomes and guide personalized medicine approaches?

43) What are the challenges and opportunities in analyzing “omics” data (genomics, proteomics, transcriptomics) to uncover novel biological insights?

44) Or how can bioinformatics contribute to our understanding of microbial diversity, evolution, and interactions within ecosystems?

Regenerative medicine

While definitely not one of the easy biology research topics, regenerative medicine will appeal to those interested in healthcare. Research innovative approaches to stimulate tissue and organ regeneration, using stem cells, tissue engineering, and biotechnology. And while you’re at it, discover the next potential medical breakthrough.

45) How can stem cells be directed to differentiate into specific cell types for tissue regeneration, and what factors influence this process?

46) Or what are the potential applications of 3D bioprinting in creating functional tissues and organs for transplantation?

47) How can bioengineered scaffolds enhance tissue regeneration and integration with host tissues?

48) What are the ethical considerations surrounding the use of stem cells and regenerative therapies in medical treatments?

49) And can regenerative medicine approaches be used to treat neurodegenerative disorders and restore brain function?

Biology Research Topics – Final thoughts

So as you take your next steps, try not to feel overwhelmed. And instead, appreciate the vast realm of possibilities that biology research topics offer. Because the array of biology topics to research is as diverse as the ecosystems it seeks to understand. And no matter if you’re only looking for easy biology research topics, or you’re itching to unravel the mysteries of plant-microbe interactions, your exploration will continue to deepen what we know of the world around us.

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212 Unique Biology Research Topics For Students And Researchers

biology research topics

Every student studying something related to biology — botany, marine, animal, medicine, molecular or physical biology, is in an interesting field. It’s a subject that explores how animate and inanimate objects relate to themselves. The field unveils the past, the present, and what lies in the future of the relationship between the living and nonliving things.

This is precisely why you need custom and quality biology topics for your college and university essay or project. It’ll make it easy to brainstorm, research, and get to writing straight away. Before the deep dive, what is biology?

What Is Biology?

Everyone knows it’s the scientific study of life, but beyond that, biology facilitates the comprehension of living and nonliving things. It’s a branch that explores their anatomy, behavior, distribution, morphology, and physiology.

For example, it understands how genes are classified and constituted into generations. It encompasses various branches, including botany, medicine, genetics, ecology, marine biology, zoology, and molecular biology.

Here are what some of these mean:

Botany: This study of plants examines their structure, physiology, ecology, economic importance, and distribution, among others. It also deals with their biochemical processes, properties, and social interactions between plants. It extends to how plants are vital for human life, survival, and growth and how they play a significant role in stabilizing environmental health. Zoology: Zoology studies animal behavior, brain, structure, physiology, class, and distribution. It’s the general study of the lives of both living and extinct animals. It explains animal classification, the animal kingdom, evolution, habitat, embryology, and life span. Physiology: Physiology deals with the daily functions of the human body: How it works and the factors that make it work. It examines molecular behavior, the chemistry and physics behind locomotion, and how the cells in the living organisms’ body function. It helps understand how humans and animals get sick and what can be done to alleviate pain. Microbiology: Dealing with microorganisms, it examined how viruses, algae, fungi, bacteria, protozoa, and slime molds become parts of human life. They’re regarded as microbes, which play substantial roles in the human biochemical processes, including climate change, biodegradation, biodeterioration, food spoilage, biotech, and epidemiology. Marine Biology: This is the scientific study of organs in the sea. It understands their family classification, how they survive, and what makes wild marine animals different from domesticated and consumable ones. It also explores their interaction with the environment through several processes. The marine biologist studies marines in their natural environment, collects data on their characteristics, human impact on their living, and how they relate with themselves.

Now that you know all these, here are some custom biology topics to research for your university or college essay and paper.

Controversial Biology Topics

There are many controversial subjects in every field, and biology isn’t exempt from controversy. If you’d like to create an original essay through diverse opinions, here are biology topics for you:

  • What are your thoughts on the post-Roe V Wade world?
  • How can the post-Roe V Wade policy affect developing countries looking up to America for their laws?
  • Abortion and feminism: discuss
  • Does saving life justify cloning?
  • Explain the principle of abortion in medical practice
  • The effects of cloning in medicine
  • How does genetics contribute to obesity?
  • Explain why a parent could have Hepatitis B virus and only one of five offspring have the virus
  • Is homosexuality really in the gene?
  • How does depression correlate with genetics?
  • Additives and how they affect the genes
  • Examine how genetic mutations work
  • Discuss the grounds that you could prove for legalizing human cloning
  • Which is more immoral: Human or animal cloning?
  • How is nanotechnology different from biotechnology?
  • Discuss the manifestation of nanotechnology in science
  • Explain three instances where public opinion has held back scientific inventions
  • How does transgenic crop work?
  • Would you say genetically modified food is safe for consumption?
  • Explain why sexual abuse leads to trauma.

Biology Research Paper Topics

You’d need to write an extensive paper on biology one day. This could be when you’re in your final year in college or the university or submitting to a competition. You’d need Biology topics to research for brainstorming, and here are 30 of them:

  • Stem cells and tissue formation processes
  • Why are there different congenital disabilities?
  • Mixtures in anticancer drugs?
  • What are the complexities of existing HIV drugs?
  • What is the contribution of chemotherapy to cancer?
  • Examine the chemotherapy process and why it doesn’t work for some patients.
  • Explain the origin of developmental diseases
  • How do germs affect the cells?
  • What are the consequences of the sun on the white person’s and black person’s skin?
  • Why are some diseases treatable through drugs while some are not?
  • Scientific lessons learned from COVID-19 and ideas to tackle the next virus
  • If animals are carriers of the virus, what should be done to them?
  • Examine five animals in extinction and what led to it
  • Discuss the subject of endangered species and why people should care
  • Is a plant-based diet sustainable for human health?
  • Account for the consequence of living on Mars on human health
  • Discuss the inconveniences involved in space travel
  • How does space flight contribute to environmental disasters
  • Discuss the emergence of leukemia
  • Explain how the immune systems in humans work
  • Evaluate the factors that weaken the immunological system
  • What would you consider the deadliest virus?
  • Autoimmune: what is it, origin and consequences
  • Immune disorder: origin and how it affects the body
  • Does stress affect the ability to have sex?
  • Contribution of vaccine to eradicating disease: Discuss
  • What are the complexities in taking the Hepatitis B vaccine while being positive?
  • Allergies: why do humans have them?
  • DNA modification: how does it work?
  • Explain the misconceptions about the COVID-19 vaccines.

Interesting Biology Topics

Biology doesn’t have to be boring. Different aspects of biology could be fun to explore, especially if you’ve had a flair for the study since your elementary school classes.

You can either write an essay or paper with the following interesting biology research topics:

  • Human emotions and conflicts with their intellectual intelligence
  • Emotions: Its influence on art and music and how the perception of art influences the world
  • The consequences of marijuana and alcohol on teenagers
  • Compare and contrast how alcohol affects teenagers and adults
  • Discuss the contributions of neuroscience to the subject of emotional pain
  • Explain how the brain process speech
  • Discuss the factors that cause autism
  • Explain what is meant when people say humans are animals
  • Why do scientists say humans are pessimists?
  • Factors contributing to the dopamine levels human experience
  • How does isolation affect the human brain?
  • What factors contribute to instinctive responses?
  • Noise pollution: how it affects living organisms
  • Fire ecology: The contributions of plants to fire outbreak
  • Explain the science behind how hot temperature, soil, and dry grass start a fire
  • Microbes: what do you understand by bioremediation?
  • Explain urban ecology and the challenges it pokes to solve
  • Discuss how excessive internet usage affects the human memory
  • Evaluate how conservation biology contributes to the extinction prevention efforts
  • Discuss the role of satellites and drones in understanding the natural world
  • Why do we need space travel and studies?
  • Explain the limitations of limnology studies
  • What are infectious-disease-causing agents all about?
  • Discuss what epigenetics studies encompass
  • Why is cancer research essential to the world?
  • Discuss climate change: Governments are not interested, and there is no alternative
  • How is behavioral science studies a core part of the understanding of the world?
  • Discuss the issues with genetic engineering and why it’s a challenge
  • Evaluate the strengths and weaknesses in the arguments for a plant-based diet
  • Create a survey amongst students of biology asking why they chose to study the course.

Biology Research Topics For College Students

If you find any of the above beyond your intellectual and Research capacity, here are some topics you can handle. You can use these for your essays, projects, quizzes, or competitions.

These custom yet popular biology research topics will examine famous personalities and other discourse in biology:

  • Effects of the human hormone on the mind
  • Why do men get erect even when they’re absentminded?
  • How does women’s arousal work?
  • How can melatonin be valuable for therapy?
  • Risky behavior: Hormones responsible for the risk
  • Stem and cloning: what is the latest research on the subject?
  • Hormones: changes in pregnancy
  • Why do pregnant women have an appetite for random and remote things?
  • The role of physical activities in hormone development
  • Examine the benefits and threats of transgenic crops
  • The fight against COVID-19: assess current successes
  • The fight against smallpox: assess current successes
  • The fight against HIV: history, trends, and present research
  • Discuss the future of prosthetic appliances
  • Examine the research and the future of mind-controlled limbs
  • What does cosmetic surgery mean, and why is it needed?
  • Analyze the meaning and process of vascular surgery
  • Discuss the debate around changes in genital organs for males and females in transgender bodies
  • How do donors and organ transplants work?
  • Account for the work of Dr. Malcom E Miller
  • Discuss the contribution of Charles Darwin to human evolution
  • Explain the trends in biomedicine
  • Discuss the functions of x-rays in botany
  • Assess the most efficient systems for wildlife preservation
  • Examine how poverty contributes to climate hazards
  • Discuss the process involved in plant metabolism
  • The transformation of energy into a living thing: discuss
  • Prevention for sexually transmitted disease: What are the misconceptions?
  • Analyze how the human body reacts to poison
  • Russian Poisoning: What are the lessons scientists must learn?
  • COVID-19: Discuss the efforts by two or three governments to prevent the spread
  • Discuss the contributions of Pfizer during the pandemic.

Marine Biology Research Topics

This subject explains orgasms in the sea, how they survive, and their interaction with their environment. If you have a flair for this field, the following Biology research topics may interest you:

  • Discuss what quantitative ecology through modeling means
  • Smallest diatoms and marine logistics: discuss
  • How is the shark studied?
  • Acidification of seas: Causes and consequences
  • Discuss the concept of the immortality of Jellyfishes
  • Discuss the differences between seawater and freshwater in marine study
  • Account for some of the oldest marine species
  • Discuss the evolution of the deep sea
  • Explain whales’ communication techniques
  • What does plankton ecology encompass?
  • The importance of coral reefs to seawater
  • Challenges that encompass geological oceanography
  • How tourism affects natural animal habitat
  • Discuss some instances of the domestication of wild marine animals
  • Coastal zone: pros and cons of living in such areas
  • How do sharks perceive enemies?
  • Analyze why some animals can live in water but can’t live on land
  • Explain how plants survive in the sea
  • Compare and contrast the different two species of animals in the water
  • How can marine energy be generated, stored, and used?

Molecular Biology Research Topics

Focusing on the construct of cells and analysis of their composition, it understands the alteration and maintenance of cellular processes. If you’d like to focus on molecular biology, here are 15 good biology research topics for you:

  • Ethical considerations in molecular genetics
  • Discuss the structure and component of the gene
  • Examine the restrictions in DNA
  • What are the peculiarities in modern nucleic acid analysis
  • What goes into the Pharmaceutical production of drugs
  • Evaluate the building blocks of life
  • Discuss the systems of RNA translation to protein
  • PCR: How DNA is tested and analyzed
  • Why is prion disease so dangerous?
  • Compare and contrast recessive genes vs. dominant genes
  • Can there be damage to the human DNA, and can it be repaired?
  • Constraints in the research of microarray data analysis
  • Protein purification: How it evolves
  • Objectives of nucleic acid
  • Explain the structure of a prion.

Biology Research Topics For High School

Your teachers and professors will be awed if you create impeccable essays for your next report. You need to secure the best grades as you move closer to graduation, and brainstorming any of these popular biology research topics will help:

  • Identify the most endangered species
  • The challenges to animal extinction
  • What are the things everyone should know about sea life?
  • Discuss the history of genetics
  • Explain the biological theory of Charles Darwin
  • How did the lockdown affect social interaction?
  • Why do some people refuse the vaccine?
  • Origin of genetics
  • What is animal hunting, and why is it fashionable
  • Explain the evolution of a virus
  • Role of lockdown in preventing deaths and illnesses
  • Invasive species: What does it mean?
  • Endangered animals: How do they survive in the face of their hazards?
  • Lockdown and their role in reducing coronavirus transmission
  • Vaccine distribution: Ideas for global distribution
  • Why can viruses become less virulent?
  • Discuss the evolution of the world
  • Explain the evolution of the planet
  • Explain what Elon Musk means when he says life on Mars is possible
  • What does herd immunity mean?
  • Flu: why is there a low incidence in 2020?
  • Relationship between archaeology and biology
  • Antiviral drug: What it means
  • Factors leading to the evolution of humans
  • Give instances of what natural selection means
  • What is considered the dead branches of evolution
  • Whale hunting: What it means and the present trends
  • Who is Stephen Jay, and what is his role in paleontology?
  • Origin of diseases: why must humans fall sick?
  • Why are humans called higher animals?

Human Biology Research Topics

Human biology understands humans and their relationship between themselves and their environment. It also studies how the body works and the impediments to health. Here are some easy biology research topics to explore on the subject:

  • How do gut bacteria affect the brain?
  • What are the ethical concerns around organ transplants?
  • The consequence of alcohol on the liver
  • The consequences of extreme salt on the human body
  • Why do humans need to deworm regularly?
  • The relationship between obesity and genetics
  • Genetically modified foods: Why are they needed?
  • How sun exposure affects human skin
  • Latest trends: Depression is hereditary
  • Influence of music on the human brain
  • What are the stages of lung cancer
  • Forensic DNA: latest trends
  • How visual consumptions affect how humans think
  • What is the process that leads to pregnancy?
  • Explain the role of nanotechnology in HIV research
  •  Discuss any experiment with stem cells you know about
  • Explain how humans consume food
  • Discuss the process of metabolism as well as its criticality to human health
  • Explore the consistent challenges technology poses to human health
  • Explain the process of body decay to a skeleton.

Cell Biology Research Topics

There are many evolutionary biology research paper topics formed not by the nomenclature but for what they stand for. Cell biology is one of the most complex branches of the field.

It examines minor units and the living organisms that make them up. The focus is on the relationship between the cytoplasm, membrane, and parts of the cell. Here are some topics to explore for your scientific dissertation writing :

  • How does chromatin engage in the alterations of gene expression?
  • What are the usual cell infections, and why does the body have immunity defections?
  • Identify and account for the heritage of Robert Brown in his core career focus
  • Explain the structure of the animal cell and why It’s what it is
  • Identify the cells in the human body as well as their functions
  • Explain a scenario and justify the context of animals photosynthesizing like plants
  • Why do bacteria invade the body, and how do they do it?
  • Why are mitochondria considered the powerhouse of the cell
  • Use the molecular analysis tool to explain multicellular organisms
  • Examine how the White blood cells fight disease
  • What do you understand about the role of cell biology in the treatment of Alzheimer’s Disease
  • What are the latest research methods in cell biology?
  • Identify the characteristics of viruses and why they threaten human existence.
  • Discuss the differences between DNA and RNA
  • What part of the body is responsible for human functionality for as long as the individual wants?

Get Biology Research Help As Soon As Possible

Creating the best essays or papers is easier now that you have custom biology research topics. However, you may still need support writing your paper beyond these topic ideas. After all, the first stage of writing like experts is brainstorming ideas and researching which is most feasible to write about.

If you truly want to wow your professor or teacher but can’t afford to dedicate all the required time, here’s an alternative. You can hire writing helpers online for quality papers at a cheap price, and we can help with that. We are a team of writers with many years of writing experience for students in Europe and North America. You can even buy thesis online with us, as well as editing services.

Each paper is assigned to writers with expertise in a specific field. This enables them to provide in-depth analysis as your assignment requires. We’re based online, which means you won’t have issues with accessibility and availability. Just tell us what you need, and we will get it done.

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350+ Biology Research Topics

Biology Research Topics

Biology is a vast field of study that explores the diverse aspects of life, from the smallest organisms to the complex ecosystems they inhabit. With new discoveries being made every day, the field of biology is constantly evolving and expanding. As a result, there are numerous research topics within biology that can capture the imagination of students, researchers , and professionals alike. Whether you’re interested in genetics, ecology, microbiology, or any other subfield of biology, there is no shortage of fascinating topics to explore. In this post, we will discuss some of the most compelling biology research topics that you can delve into.

Biology Research Topics

Biology Research Topics are as follows:

  • The role of gut microbiota in human health and disease.
  • The effects of climate change on animal behavior and physiology.
  • The molecular mechanisms of cancer development and progression.
  • The evolutionary origins of human language.
  • The impact of pesticides on insect populations and ecosystems.
  • The genetic basis of aging and longevity.
  • The ecological importance of microbial communities in soil.
  • The physiology and behavior of marine mammals.
  • The molecular mechanisms of viral infections.
  • The evolutionary history of flowering plants.
  • The ecological impacts of invasive species.
  • The role of epigenetics in gene regulation and disease.
  • The evolution of social behavior in animals.
  • The physiology and ecology of birdsong.
  • The impact of antibiotics on gut microbiota and human health.
  • The role of the microbiome in psychiatric disorders.
  • The evolutionary history of human migrations.
  • The ecological and physiological effects of light pollution on animals.
  • The mechanisms of cell division and differentiation.
  • The ecological impacts of deforestation.
  • The molecular mechanisms of drug addiction.
  • The genetic basis of plant resistance to pests and diseases.
  • The evolutionary history of human diet and nutrition.
  • The molecular mechanisms of neurodegenerative diseases.
  • The ecology and evolution of sexual selection.
  • The physiological and behavioral effects of air pollution on animals.
  • The role of epigenetics in plant development and stress response.
  • The evolutionary history of animal domestication.
  • The molecular mechanisms of genetic diseases.
  • The ecological impacts of climate change on plants.
  • The evolutionary history of human mating systems.
  • The physiological and behavioral effects of noise pollution on animals.
  • The genetic basis of intelligence and cognitive abilities.
  • The ecological and physiological effects of ocean acidification on marine organisms.
  • The molecular mechanisms of immune system function and dysfunction.
  • The evolutionary history of human social structures.
  • The ecological impacts of plastic pollution on marine ecosystems.
  • The genetic basis of animal migration.
  • The physiological and behavioral effects of light and dark cycles on animals.
  • The ecological and evolutionary dynamics of symbiosis.
  • The molecular mechanisms of gene regulation and expression.
  • The evolutionary history of human disease resistance.
  • The ecological impacts of overfishing on marine ecosystems.
  • The genetic basis of animal communication.
  • The physiological and behavioral effects of temperature changes on animals.
  • The ecological and evolutionary dynamics of parasitism.
  • The molecular mechanisms of circadian rhythms.
  • The evolutionary history of human social cognition.
  • The ecological impacts of urbanization on wildlife.
  • The genetic basis of antibiotic resistance in bacteria.
  • The impact of climate change on insect population dynamics.
  • The role of the microbiome in the development of autoimmune diseases.
  • The genetic basis of complex human diseases such as diabetes and heart disease.
  • The evolution of plant secondary metabolites and their ecological functions.
  • The effects of anthropogenic noise on animal communication and behavior.
  • The molecular mechanisms of protein synthesis and folding.
  • The role of RNA in gene expression and regulation.
  • The ecology and evolution of microbial symbioses in plants.
  • The physiological and behavioral effects of air temperature changes on animals.
  • The genetic basis of crop domestication and improvement.
  • The evolution of reproductive strategies in animals.
  • The impacts of plastic pollution on terrestrial ecosystems.
  • The molecular mechanisms of stem cell differentiation and regeneration.
  • The ecological dynamics of predator-prey interactions.
  • The role of gut microbiota in the regulation of host metabolism.
  • The genetic basis of host-pathogen coevolution.
  • The evolution of social cognition and cooperation in animals.
  • The ecological and physiological effects of wildfires on ecosystems.
  • The molecular mechanisms of transcriptional regulation in eukaryotic cells.
  • The role of microorganisms in soil nutrient cycling and ecosystem functioning.
  • The genetic basis of plant-pathogen interactions.
  • The ecology and evolution of microbial communities in the ocean.
  • The physiological and behavioral effects of water pollution on aquatic organisms.
  • The molecular mechanisms of protein degradation and turnover.
  • The impact of urbanization on pollinator populations and plant-pollinator interactions.
  • The genetic basis of insecticide resistance in pests.
  • The evolution of animal cognition and perception.
  • The ecological and evolutionary dynamics of host-parasite interactions.
  • The role of epigenetic modifications in plant adaptation to environmental stress.
  • The physiological and behavioral effects of endocrine disruptors on animals.
  • The molecular mechanisms of DNA replication and repair.
  • The impact of ocean warming on coral reef ecosystems.
  • The genetic basis of animal personality traits.
  • The ecology and evolution of microbial symbioses in animals.
  • The physiological and behavioral effects of light quality on plants.
  • The molecular mechanisms of RNA editing and splicing.
  • The role of microbial communities in plant-pathogen interactions.
  • The ecological and evolutionary dynamics of seed dispersal.
  • The genetic basis of animal coloration and pattern.
  • The impact of climate change on plant phenology and productivity.
  • The molecular mechanisms of signal transduction in cells.
  • The role of microbial communities in the human gut-brain axis.
  • The ecology and evolution of animal migrations.
  • The physiological and behavioral effects of chemical pollution on animals.
  • The genetic basis of animal development and morphogenesis.
  • The evolution of animal social behavior and communication.
  • The ecological dynamics of plant-pollinator networks.
  • The molecular mechanisms of intracellular trafficking and transport.
  • The role of microbial communities in the degradation of pollutants.
  • The ecological and evolutionary dynamics of species interactions in ecological communities.
  • The role of epigenetics in cancer development and progression.
  • The molecular basis of antibiotic resistance in bacteria.
  • The impact of climate change on biodiversity and ecosystem functioning.
  • The genetic basis of aging and age-related diseases.
  • The evolution of social organization in primates.
  • The ecological dynamics of plant-fungal interactions.
  • The role of microbiota in immune system development and function.
  • The molecular mechanisms of DNA damage and repair.
  • The physiological and behavioral effects of climate change on marine organisms.
  • The genetic basis of human variation and diversity.
  • The evolution of sexual selection and mate choice in animals.
  • The ecological and evolutionary dynamics of species invasions.
  • The role of microbiota in brain function and behavior.
  • The molecular mechanisms of immune system activation and regulation.
  • The physiological and behavioral effects of pollution on wildlife.
  • The genetic basis of behavioral disorders and mental illness.
  • The evolution of plant-pollinator mutualisms.
  • The ecological dynamics of predator-prey coevolution.
  • The role of microbiota in metabolic diseases such as obesity and diabetes.
  • The molecular mechanisms of protein-protein interactions and signaling.
  • The genetic basis of complex traits such as intelligence and personality.
  • The evolution of animal communication and language.
  • The ecological and evolutionary dynamics of mutualistic interactions in ecological communities.
  • The role of microbiota in the development and maintenance of gut homeostasis.
  • The molecular mechanisms of neurotransmitter synthesis and release.
  • The physiological and behavioral effects of artificial light at night on wildlife.
  • The genetic basis of developmental disorders such as autism and ADHD.
  • The evolution of host-parasite coevolution and adaptation.
  • The ecological dynamics of plant-herbivore interactions.
  • The role of microbiota in the regulation of metabolism and energy balance.
  • The molecular mechanisms of membrane transport and signaling.
  • The physiological and behavioral effects of habitat fragmentation on wildlife.
  • The genetic basis of circadian rhythms and sleep disorders.
  • The evolution of animal cognition and decision-making.
  • The ecological and evolutionary dynamics of trophic cascades.
  • The role of microbiota in the development and function of the respiratory system.
  • The molecular mechanisms of epigenetic inheritance.
  • The physiological and behavioral effects of endocrine disruptors on wildlife.
  • The genetic basis of developmental plasticity and adaptation.
  • The evolution of animal social learning and culture.
  • The ecological dynamics of predator-prey interactions in aquatic systems.
  • The role of microbiota in the regulation of host immunity and inflammation.
  • The molecular mechanisms of RNA interference and gene silencing.
  • The physiological and behavioral effects of climate change on migratory animals.
  • The genetic basis of drug addiction and substance abuse disorders.
  • The evolution of animal cooperation and conflict resolution.
  • The ecological and evolutionary dynamics of niche construction.
  • The role of microbiota in the regulation of host-microbe interactions.
  • The molecular mechanisms of gene regulation by non-coding RNAs.
  • The role of epigenetics in gene expression and regulation.
  • The molecular mechanisms of DNA damage response and repair.
  • The impact of environmental toxins on human health.
  • The evolutionary origins of viruses and their impact on hosts.
  • The genetics of aging and age-related diseases.
  • The impact of ocean acidification on marine organisms.
  • The molecular basis of cancer development and progression.
  • The genetic basis of behavior in animals.
  • The impact of environmental stressors on plant growth and productivity.
  • The evolution of sex determination and sexual selection.
  • The role of the immune system in host-microbe interactions.
  • The molecular mechanisms of circadian rhythms and sleep.
  • The impact of air pollution on respiratory health.
  • The genetic basis of speciation and hybridization.
  • The role of neurotransmitters in brain function and behavior.
  • The ecological dynamics of microbial communities in soil.
  • The impact of climate change on biodiversity and ecosystem services.
  • The molecular mechanisms of viral entry, replication, and release.
  • The genetics of plant domestication and diversification.
  • The role of mitochondrial DNA in aging and disease.
  • The impact of deforestation on ecosystem functioning.
  • The molecular basis of drug addiction and treatment.
  • The genetic basis of adaptation and evolution in response to environmental change.
  • The role of gut-brain signaling in behavior and disease.
  • The impact of noise pollution on wildlife populations.
  • The genetic basis of plant morphology and development.
  • The role of the microbiome in disease susceptibility and resistance.
  • The ecological dynamics of plant-insect interactions.
  • The impact of agricultural practices on soil health and biodiversity.
  • The molecular mechanisms of gene regulation in development and disease.
  • The genetic basis of complex traits in humans and animals.
  • The role of cytokines in immune response and inflammation.
  • The ecological dynamics of microbial communities in aquatic ecosystems.
  • The impact of plastic waste on marine ecosystems.
  • The molecular mechanisms of genome stability and repair.
  • The genetics of rare and common genetic diseases.
  • The role of the endocannabinoid system in health and disease.
  • The ecological dynamics of competition and cooperation in populations.
  • The impact of light pollution on wildlife behavior and ecology.
  • The genetic basis of animal migration and navigation.
  • The role of the microbiome in host metabolism and energy balance.
  • The impact of climate change on agricultural productivity and food security.
  • The molecular mechanisms of epigenetic inheritance and transmission.
  • The genetics of human brain development and disorders.
  • The role of pheromones in animal communication and behavior.
  • The ecological dynamics of host-microbe-pathogen interactions.
  • The effect of diet and nutrition on gut microbiome diversity and composition.
  • The ecology and evolution of microbial interactions in the soil.
  • The role of epigenetic modifications in cancer development and progression.
  • The impact of climate change on marine biodiversity and ecosystem functioning.
  • The molecular mechanisms of mitochondrial respiration and ATP synthesis.
  • The role of non-coding RNAs in gene regulation and disease.
  • The evolution and diversification of flowering plants.
  • The effects of artificial light at night on animal behavior and physiology.
  • The genetic basis of adaptation to extreme environments.
  • The ecology and evolution of plant-microbe interactions.
  • The physiological and behavioral effects of noise pollution on wildlife.
  • The molecular mechanisms of DNA methylation and histone modification.
  • The role of microbial communities in the cycling of nutrients in aquatic ecosystems.
  • The evolution of animal color vision and perception.
  • The ecological and evolutionary dynamics of mutualistic interactions.
  • The impact of deforestation on soil fertility and carbon storage.
  • The molecular mechanisms of viral replication and pathogenesis.
  • The role of microorganisms in the biodegradation of plastics.
  • The ecology and evolution of microbial communities in the human gut.
  • The physiological and behavioral effects of climate change on birds.
  • The impact of invasive species on native ecosystems.
  • The genetic basis of developmental disorders and intellectual disabilities.
  • The evolution of animal behavior and communication in response to anthropogenic change.
  • The ecological dynamics of soil carbon sequestration and storage.
  • The role of microbial communities in the decomposition of organic matter.
  • The physiological and behavioral effects of air pollution on plants.
  • The molecular mechanisms of cellular differentiation and tissue development.
  • The ecology and evolution of plant-animal interactions.
  • The genetic basis of resistance to herbicides and pesticides in crops.
  • The impact of urbanization on bird diversity and distribution.
  • The role of microorganisms in the cycling of carbon and nitrogen in soil.
  • The ecological and evolutionary dynamics of invasive species interactions.
  • The physiological and behavioral effects of climate change on reptiles and amphibians.
  • The role of microbial communities in the degradation of petroleum hydrocarbons.
  • The genetic basis of plant development and growth.
  • The evolution of animal migration and dispersal.
  • The impact of land use change on freshwater biodiversity.
  • The molecular mechanisms of membrane transport and ion channels.
  • The role of microorganisms in the cycling of sulfur and phosphorus in soil.
  • The physiological and behavioral effects of ocean acidification on marine organisms.
  • The genetic basis of behavior and personality traits in humans.
  • The evolution of plant reproductive strategies and pollination systems.
  • The ecological and evolutionary dynamics of predator-prey coevolution.
  • The impact of environmental stressors on gene expression and epigenetics.
  • The evolution of sexual reproduction and mating systems in plants.
  • The role of microorganisms in bioremediation of contaminated sites.
  • The physiological and behavioral effects of climate change on fish.
  • The molecular mechanisms of chromatin remodeling and gene regulation.
  • The genetic basis of adaptation to high altitude environments.
  • The ecology and evolution of plant-insect interactions.
  • The impact of pesticide use on insect biodiversity and ecosystem functioning.
  • The role of microorganisms in nitrogen fixation and cycling.
  • The genetic basis of neurodegenerative diseases and cognitive decline.
  • The evolution of social behavior and cooperation in animals.
  • The ecological and evolutionary dynamics of plant invasions.
  • The physiological and behavioral effects of noise pollution on humans.
  • The molecular mechanisms of RNA splicing and alternative splicing.
  • The role of microorganisms in biogeochemical cycling of trace elements.
  • The genetic basis of adaptation to extreme temperatures.
  • The ecology and evolution of microbial communities in soil and water.
  • The impact of climate change on insect phenology and distribution.
  • The molecular mechanisms of protein folding and misfolding.
  • The role of microorganisms in biodegradation of environmental pollutants.
  • The evolution of animal cognition and intelligence.
  • The ecological and evolutionary dynamics of predator-prey interactions.
  • The impact of anthropogenic noise on marine mammals.
  • The role of microorganisms in biofilm formation and quorum sensing.
  • The genetic basis of speciation and hybridization in plants.
  • The evolution of parental care and offspring development in animals.
  • The ecological and evolutionary dynamics of food web interactions.
  • The physiological and behavioral effects of air pollution on human health.
  • The molecular mechanisms of transcriptional regulation and gene expression.
  • The role of microorganisms in plant growth promotion and disease suppression.
  • The genetic basis of adaptation to drought stress in crops.
  • The ecology and evolution of microbial interactions in the ocean.
  • The impact of land use change on soil erosion and nutrient cycling.
  • The molecular mechanisms of autophagy and programmed cell death.
  • The role of microorganisms in biodegradation of pharmaceuticals.
  • The genetic basis of immune system variation and disease susceptibility.
  • The evolution of animal social networks and communication systems.
  • The ecological and evolutionary dynamics of biodiversity loss.
  • The physiological and behavioral effects of light pollution on nocturnal animals.
  • The molecular mechanisms of DNA repair and genome stability.
  • The role of microorganisms in the production of biofuels and bioplastics.
  • The genetic basis of adaptation to salinity stress in plants.
  • The ecology and evolution of microbial symbioses with plants and animals.
  • The impact of climate change on plant-pollinator interactions.
  • The molecular mechanisms of cellular senescence and aging.
  • The role of microorganisms in biodegradation of synthetic organic compounds.
  • The genetic basis of variation in complex traits in humans.
  • The evolution of animal social behavior and cultural transmission
  • The genetic basis of cancer development and progression.
  • The role of microorganisms in the gut microbiome and human health.
  • The genetic basis of phenotypic plasticity and adaptation in plants.
  • The evolution of animal migration and navigation.
  • The ecological and evolutionary dynamics of community assembly.
  • The physiological and behavioral effects of light and dark cycles on circadian rhythms.
  • The molecular mechanisms of protein synthesis and degradation.
  • The role of microorganisms in nitrogen and carbon cycling in aquatic ecosystems.
  • The genetic basis of sex determination and differentiation in animals.
  • The ecology and evolution of predator-prey coevolution.
  • The impact of anthropogenic activities on marine biodiversity and ecosystems.
  • The role of microorganisms in bioleaching and biomining of metals.
  • The genetic basis of inherited disorders and genetic diseases.
  • The evolution of animal social behavior and communication systems.
  • The ecological and evolutionary dynamics of competition and coexistence.
  • The physiological and behavioral effects of endocrine disruptors on human health.
  • The molecular mechanisms of cell division and mitosis.
  • The role of microorganisms in biodegradation of plastics and synthetic materials.
  • The genetic basis of epigenetic inheritance and regulation.
  • The ecology and evolution of mutualistic symbioses in plants and animals.
  • The impact of habitat fragmentation on species diversity and ecosystem functioning.
  • The role of microorganisms in bioremediation of oil spills.
  • The genetic basis of drug resistance in pathogens and cancer cells.
  • The evolution of animal personality and individual variation.
  • The ecological and evolutionary dynamics of biotic interactions in freshwater ecosystems.
  • The physiological and behavioral effects of artificial sweeteners on human health.
  • The molecular mechanisms of intracellular trafficking and secretion.
  • The role of microorganisms in biocontrol of plant pathogens and pests.
  • The genetic basis of hybridization and introgression in animals and plants.
  • The ecology and evolution of plant-pollinator mutualisms.
  • The impact of climate change on marine ecosystems and fisheries.
  • The molecular mechanisms of genome editing and gene therapy.
  • The role of microorganisms in biogas production and carbon capture.
  • The genetic basis of developmental disorders and birth defects.
  • The evolution of animal coloration and camouflage.
  • The ecological and evolutionary dynamics of invasive species.
  • The physiological and behavioral effects of air pollution on wildlife.
  • The molecular mechanisms of signal transduction and cell signaling.
  • The role of microorganisms in biodegradation of pharmaceuticals and personal care products.
  • The genetic basis of reproductive isolation and speciation.
  • The ecology and evolution of microbial interactions with plants and insects.
  • The impact of climate change on bird migration and breeding patterns.
  • The molecular mechanisms of protein-protein interactions and protein complexes.
  • The role of microorganisms in bioremediation of heavy metals.
  • The evolution of animal cognition and learning.
  • The ecological and evolutionary dynamics of biodiversity hotspots.
  • The impact of ocean acidification on marine ecosystems.
  • The genetics of complex diseases and personalized medicine.
  • The evolution of plant defense mechanisms against herbivores.
  • The role of microorganisms in soil carbon sequestration.
  • The physiological and behavioral effects of light on plant growth and development.
  • The molecular mechanisms of cancer metastasis and invasion.
  • The ecology and evolution of microbial communities in the human body.
  • The impact of climate change on migratory bird populations.

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Top 100 biology research topics for high school and college.

biology research topics

Writing a biology essay may not sound like a very difficult thing to do. In fact, most students really like this subject. The problem is not that you can’t write a good paper on a topic in biology. The problem is with finding excellent biology research topics. Now, you may be wondering why you would want to invest so much time into finding great biology research paper topics. After all, what you write in the essay matters more than the topic, right? Wrong! We are here to tell you that professors really appreciate interesting and unique topics.

And it makes a lot of sense, if you think about it. If you simply pick one of the most popular biology research topics, you will never be able to pique the interest of your teacher. He has read dozens, if not hundreds, or papers on that exact same topic. What you want to do is come up with interesting biology research topics. You want to find topics that none of your classmates are thinking of writing an academic paper about. You will shortly see why this is important. And we will also give you 100 biology topics for research projects that you can use for free – right now!

Biology Research Paper Topics Really Are Important!

It doesn’t matter what area of biology you need to write about. This information applies to everything from zoology and botany to anatomy. The reality is that your professor will really appreciate good topics. And you can rest assured that he or she knows how to spot them. The moment the professor starts to read your paper, he or she will immediately realize that you really did your best to find an excellent topic. And if you write a good introduction paragraph (which contains a captivating thesis statement as well), you are in the best position to earn bonus points.

You may not be aware of it, but teachers are willing to treat great papers with more leniency. This means that you will not get penalized for minor mistakes if you come up with a great topic. In other words, you will get a better grade on your papers if you manage to come up with good research topics for biology. This is a fact and it is based on thousands of pieces of feedback from our readers.

How Do You Choose Good Biology Research Topics?

Choosing research topics for biology can be a daunting task. Frankly, the research paper topics biology students are looking for are not easy to come by. The first thing you want to avoid is going to the first website that pops up in Google and getting your ideas from there. Most of your peers will do the same. Also, avoid topics that are extremely simple. You will simply not have enough ideas to write about. Of course, you should avoid overly complex topics because finding information about them may be extremely difficult.

The best way to find a good topic, in our opinion, is to get in touch with an academic writing company. You will get access to a professional writer who knows exactly what professors are looking for. A writer will quickly give you an amazing research topic in biology.

Eloquent Examples of Popular Biology Research Topics

To make things as simple as possible for you, we’ve put together a list of biology research project ideas. You will find 100 topics on various subjects below. Of course, you can use any of our topics for free. However, keep in mind that even though we are doing our best to maintain this list fresh, other students will find it as well. If you need new topics for your next biology essay, we recommend you to get in touch with us. We monitor our email address, so we can help you right away. Also, you can buy a research paper from our service.

Biology Research Topics for High School

Are you looking for biology research topics for high school? These are relatively simple when compared to college-level topics. Here are a couple of topic ideas that high school students will surely appreciate:

  • Identifying Three Dead Branches of Evolution.
  • What Is Sleep?
  • How Does Physical Exercise Affect the Metabolism?
  • A Behavioral Study of Birds.
  • How Does Music Affect Your Brain?
  • Climate Change and Biodiversity.
  • Are Bees Really Becoming Extinct?
  • Rainforest Extinction Is Dangerous.
  • The Benefits of Organic Farming.
  • Can the Brain Repair Itself?
  • The Effect of Bacteria on Depression.
  • How Do Sea Animals Camouflage?

Research Topics in Biology for Undergraduates

Research topics in biology for undergraduates are more complex than high school or college topics. Our researchers did their best to find topics that are relatively complex. However, each one of the following topics has plenty of information about it online:

  • What Is the Mechanism of Metastasis in Cancer Patients?
  • How Do Tumor Suppressor Genes Appear?
  • How Can We Destroy Cancer Cells Without Damaging Other Cells?
  • The Benefits of Gene Therapy.
  • Analyzing the Huntington’s Disease (the HTT Gene).
  • How Does the down Syndrome (Trisomy of 21st Chromosome) Appear?
  • Analyzing the Brain Activity During an Epileptic Seizure.
  • How Are Our Memories Formed and Preserved?
  • The Effect of Probiotics on Infections.
  • Analyzing Primate Language.
  • Analyzing Primate Cognitive Functions.
  • The Link Between Darwin’s Theory and Biology.

Biology Research Topics for College Students

Biology research topics for college students are of moderate difficulty. They are easier than undergrad topics and more complex than high school topics. While compiling this list, we made sure you have more than enough information online to write the paper quickly:

  • Using DNA Technology in the Field of Medical Genetics.
  • The Effect of Drinking on Embryonic Development.
  • How Are Genes Mapped and Cloned?
  • Explain What Genetic Polymorphism Is.
  • What Is a Hereditary Disease?
  • The Effect of Drugs on Embryonic Development.
  • Describing Oligogenic Diseases (like Hirschsprung Disease)
  • What Is the Mendelian Inheritance?
  • How Transcriptomics and Proteomics Changed Modern Medicine.
  • The Risk Factors of Infertility Explained.
  • How Does Aging Effect Infertility?
  • What Do Ash Elements Do in a Plant?
  • Explaining the Pigments in a Plant Cell.
  • How Is Photosynthesis Done?
  • The Role of Fats in Plant Cells.
  • The Effect of Smoking on Embryonic Development.

Cell Biology Research Topics

Some of the best biology topics are cell biology research topics. The scientific community is constantly making progress in this area, so there is always something new to write about. Here are some of the best examples:

  • What Is Regenerative Medicine?
  • A Closer Look at Tissue Engineering.
  • Discuss the Future of Regenerative Medicine.
  • Analyzing Therapeutic Cloning.
  • The Pros and Cons of Creating Artificial Organs.
  • How Do Cell Age?
  • Can We Reverse Cell Aging?
  • Advances in Cell Therapy.
  • What Is Cell Adhesion?
  • Explaining Cell Division.
  • What Is Cellular Metabolism?
  • Describe Active and Passive Transport in Cells.
  • What Are Cell Plastids?

Evolutionary Biology Research Paper Topics

If you want something more complex, you can try your hand at writing on evolutionary biology research paper topics. As with all our topics, you will be able to find a lot of ideas and information online. Here are our picks:

  • Where Did Plants Come From? (The Evolutionary Theory)
  • Explaining the Host-parasite Coevolution.
  • How Did Parasites Evolve over Time?
  • What Is Natural Selection and How Does It Work?
  • Explain Sexual Selection.
  • Explain Sexual Conflict.
  • How Did Our Immune Systems Evolve?
  • How Do New Species Appear in the Wild?
  • The Evolution of Cell Respiration.
  • What Is the Hippo Pathway? (Developmental Biology)

Various Topics

Antibiotics resistance, agriculture and cloning are hot subjects nowadays. Your professor will surely be interested to learn more about biology research topics. Here is a mix of topic ideas from our established community of academic writers:

  • The Problem of Using Antibiotics on Large Scale.
  • Examining the Effects of Salt on Plants.
  • What Is DNA Technology?
  • The Effects of GMOs on the Human Body.
  • How Is the Quality of Antibiotics Controlled?
  • How Are GMO Food Crops Created?
  • The Effect of Veterinary Antibiotics on Humans.
  • The Allergic Reactions to Specific Antibiotics.
  • A Look at How Penicillin Works in the Human Body.
  • How Are Antibiotics Obtained?
  • What Are Natural Biochemicals with Pest-repellent Properties?
  • The 3 Most Toxic Effects of Antibiotics
  • How the Human Body Develops Resistance to Antibiotics.
  • The Impact of Biology on the Us Agriculture.
  • What Is the Green Revolution?
  • Analyzing the Minerals in the Plant Cell.
  • Analyzing Muscle Development and Regeneration
  • The Uses of Cancer Stem Cells.

Marine Biology Research Topics

There is a lot of talk about global warming, about microplastics in our oceans, and about endangered marine species. This means that marine biology research topics are a very hot topic today. Here are some of our best ideas:

  • Can GMO Organisms Break down Oil after Maritime Accidents?
  • Pollution-absorbing Bio-films.
  • Microbes That Can Absorb Toxic Compounds in the Water.
  • Can We Really Use Bioluminescence?
  • How Is Bio-diesel Created?
  • Analyzing the Coral Reef Biology.
  • Why Is the Lobster Population Dwindling?
  • The Effect of Mass Fishing on the World’s Oceans.
  • Global Warming and Its Effect on Marine Microorganisms.

Molecular Biology Research Topics

Writing about molecular biology research topics is not easy. However, it’s a foolproof way to get a top grade. Your professor will really appreciate your willingness to write an essay about a complex topic. Just make sure you know what you are talking about. Below you can find some of the best topics:

  • How Is Insulin Produced?
  • How Is the Growth Hormone Produced?
  • Analyzing the Repropagation of Translation.
  • What Is DNA-telomerase?
  • The Process of Sequencing Nucleotides in DNA.
  • What Is Telomerase?
  • The Link Between Telomerase and Cancer.
  • The Link Between Telomerase and Aging.
  • How Does DNA Forensics Work?
  • Describe the Process of Protein Metabolism.

There is no such thing as easy biology research topics. When the topic is too simple, you end up getting penalized. You can’t write 500 words about it without straying away from the subject. Also, no matter how interesting the topic may be, you should make sure that the essay is written perfectly. This means that not even interesting biology research topics can save you from a bad grade if you fail to follow all applicable academic writing standards.

Find it hard to cope with your college paper? Great news! Use promo “ mypaper20 ” and enjoy 20% discount on a biology writing assignment from our profs!

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In vitro incubation of epididymal and vas deferens sperm with Mn 2+ induces Sperm Chromatin Fragmentation (SCF), a mechanism that causes double-stranded breaks in toroid-linker regions (TLRs). Whether this mechani...

Focal ischemic stroke modifies microglia-derived exosomal miRNAs: potential role of mir-212-5p in neuronal protection and functional recovery

Ischemic stroke is a severe type of stroke with high disability and mortality rates. In recent years, microglial exosome-derived miRNAs have been shown to be promising candidates for the treatment of ischemic ...

S -Nitrosylation in endothelial cells contributes to tumor cell adhesion and extravasation during breast cancer metastasis

Nitric oxide is produced by different nitric oxide synthases isoforms. NO activates two signaling pathways, one dependent on soluble guanylate cyclase and protein kinase G, and other where NO post-translationa...

Identifying pyroptosis- and inflammation-related genes in intracranial aneurysms based on bioinformatics analysis

Intracranial aneurysm (IA) is the most common cerebrovascular disease, and subarachnoid hemorrhage caused by its rupture can seriously impede nerve function. Pyroptosis is an inflammatory mode of cell death wh...

Drosophila Atlastin regulates synaptic vesicle mobilization independent of bone morphogenetic protein signaling

The endoplasmic reticulum (ER) contacts endosomes in all parts of a motor neuron, including the axon and presynaptic terminal, to move structural proteins, proteins that send signals, and lipids over long dist...

Mucin1 induced trophoblast dysfunction in gestational diabetes mellitus via Wnt/β-catenin pathway

To elucidate the role of Mucin1 (MUC1) in the trophoblast function (glucose uptake and apoptosis) of gestational diabetes mellitus (GDM) women through the Wnt/β-catenin pathway.

Human umbilical cord mesenchymal stem cells (hUC-MSCs) alleviate paclitaxel-induced spermatogenesis defects and maintain male fertility

Chemotherapeutic drugs can cause reproductive damage by affecting sperm quality and other aspects of male fertility. Stem cells are thought to alleviate the damage caused by chemotherapy drugs and to play role...

Exploring the Neandertal legacy of pancreatic ductal adenocarcinoma risk in Eurasians

The genomes of present-day non-Africans are composed of 1–3% of Neandertal-derived DNA as a consequence of admixture events between Neandertals and anatomically modern humans about 50–60 thousand years ago. Ne...

Identification and analysis of key hypoxia- and immune-related genes in hypertrophic cardiomyopathy

Hypertrophic cardiomyopathy (HCM), an autosomal dominant genetic disease, is the main cause of sudden death in adolescents and athletes globally. Hypoxia and immune factors have been revealed to be related to ...

research topic in biology

How do prolonged anchorage-free lifetimes strengthen non-small-cell lung cancer cells to evade anoikis? – A link with altered cellular metabolomics

Malignant cells adopt anoikis resistance to survive anchorage-free stresses and initiate cancer metastasis. It is still unknown how varying periods of anchorage loss contribute to anoikis resistance, cell migr...

Single nucleotide polymorphisms associated with wine fermentation and adaptation to nitrogen limitation in wild and domesticated yeast strains

For more than 20 years, Saccharomyces cerevisiae has served as a model organism for genetic studies and molecular biology, as well as a platform for biotechnology (e.g., wine production). One of the important eco...

Investigating the dark-side of the genome: a barrier to human disease variant discovery?

The human genome contains regions that cannot be adequately assembled or aligned using next generation short-read sequencing technologies. More than 2500 genes are known contain such ‘dark’ regions. In this st...

Hyperbaric oxygen treatment increases intestinal stem cell proliferation through the mTORC1/S6K1 signaling pathway in Mus musculus

Hyperbaric oxygen treatment (HBOT) has been reported to modulate the proliferation of neural and mesenchymal stem cell populations, but the molecular mechanisms underlying these effects are not completely unde...

Polar microalgae extracts protect human HaCaT keratinocytes from damaging stimuli and ameliorate psoriatic skin inflammation in mice

Polar microalgae contain unique compounds that enable them to adapt to extreme environments. As the skin barrier is our first line of defense against external threats, polar microalgae extracts may possess res...

Correction: Utility of melatonin in mitigating ionizing radiation‑induced testis injury through synergistic interdependence of its biological properties

The original article was published in Biological Research 2022 55 :33

Beyond energy provider: multifunction of lipid droplets in embryonic development

Since the discovery, lipid droplets (LDs) have been recognized to be sites of cellular energy reserves, providing energy when necessary to sustain cellular life activities. Many studies have reported large num...

Retraction Note: Tridax procumbens flavonoids: a prospective bioactive compound increased osteoblast differentiation and trabecular bone formation

Electroacupuncture protective effects after cerebral ischemia are mediated through mir-219a inhibition.

Electroacupuncture (EA) is a complementary and alternative therapy which has shown protective effects on vascular cognitive impairment (VCI). However, the underlying mechanisms are not entirely understood.

Topsoil and subsoil bacterial community assemblies across different drainage conditions in a mountain environment

High mountainous environments are of particular interest as they play an essential role for life and human societies, while being environments which are highly vulnerable to climate change and land use intensi...

Functional defects in hiPSCs-derived cardiomyocytes from patients with a PLEKHM2-mutation associated with dilated cardiomyopathy and left ventricular non-compaction

Dilated cardiomyopathy (DCM) is a primary myocardial disease, leading to heart failure and excessive risk of sudden cardiac death with rather poorly understood pathophysiology. In 2015, Parvari's group ident...

Human VDAC pseudogenes: an emerging role for VDAC1P8 pseudogene in acute myeloid leukemia

Voltage-dependent anion selective channels (VDACs) are the most abundant mitochondrial outer membrane proteins, encoded in mammals by three genes, VDAC1 , 2 and 3 , mostly ubiquitously expressed. As 'mitochondrial ...

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149+ Most Interesting Biology Research Topics In 2023

Writing a biology research paper is one of the most complicated assignments during college study. The reason behind this is that it requires deep analysis of a scientific topic that becomes time-consuming.

If you are also assigned to write a biology research paper, three questions you should ask yourself.

  • What sources do you have to use to get information?
  • What should be my starting point?
  • How can I edit my research paper?

But one question you can’t ignore to ask yourself is what topic I should choose for my research paper.

In this blog, we will discuss top biology research topics that will definitely help you to get good scores.

Get the best Biology Research paper help from our professional experts. They will provide you top-notch & Plagiarism-free content within the given deadline at an affordable price.

What Is Biology?

Table of Contents

Do you know what is biology? It is the science of life or the study of living organisms. That wraps their development, physiology, origin, anatomy, behavior, evolution, etc.

Furthermore, biological disciplines can cover a wide range of topics such as plant cell structure, human DNA, animal neurobiology, immunology, hormones, stem cell treatments, and beyond.

If you can’t think of an exciting topic and are feeling stuck writing about them, just figure out a complete list of biology research paper topics and ideas to get some motivation.

What Are Good Biology Research Topics?

A good biology research paper should challenge readers to think differently and inspire meaningful conversations. Moreover, it must be relevant and have the potential to make an impact on the community.

It doesn’t matter what it’s about – animals, humans, plants, ecology, etc. – as long as it addresses something from a new perspective, makes a new discovery, shows a link between two organisms or phenomena, or potential leads to a scientific breakthrough.

There is great potential to be explored in order to gain a better understanding of life and living organisms. Here are the following good biology research topics.

149+ Most Interesting Biology Research Topics

Here are the following best biology research topics that given below.

research topic in biology

If you are asked to write a biology research paper, covid-19 is the current issue you can consider. Covid-19 affected almost all the nation in the last two years and led to various problems such as losses of lives, economic problems, unemployment, etc. You can write on-

  • Evolution of coronavirus
  • Different Stages of covid-19
  • How covid affected different economies/
  • Strategies to get rid of this pandemic.

Cell Biology Research Topics

Cell biology developments can prevent disease and eradicate viruses. For biology students, it can be rewarding to write a paper in this area. Here a student can consider different topics under a cell. For example, students can write on-

  • Cell Structure
  • DNA and RNA
  • Characteristics of viruses
  • Research methods in cell biology

Biology Research Topics For High School

Here are the following easy biology research topics for high school students.

Biology Research Topics For College Students

Let’s know some of the best topics of biology for college students, it’s given below?

Genetics Research Topics

These are the following genetics research topics given below.

Botany Research Topics

If you are interested in plants and their studies, you can write on botany topics. Here you can talk about the current developments in botany to score well. Your botany research paper topics may be-

  • Plant Growth control
  • Photosynthesis
  • Innovations in plant research
  • Genetic inheritance in plant species
  • Ferns study

Neurobiological Research Paper Topics

The human brain has many things to learn, and understanding the brain is quite interesting. If you are curious to learn about the human brain and want to know about it, you can consider the below topics.

  • Brain Injuries
  • Chronic Fatigue Syndrome- biological makers
  • Human memory
  • An analysis of the visual cortex
  • Relation between depression and oxidative stress.

Zoology Research Topics

There are the following most interesting biology research topics for presentation.

Behaviour and Hormones Biology Research Topics

Behavior and hormones are a huge part of biology. Students can write about the influence of hormones on our mood and physical growth. They can also consider some disorders. Below are few topics that a student should write on-

  • Influence of hormonal therapy
  • How hormones related to depression
  • Oxytocin and fear reaction
  • Melatonin in therapy
  • Cardio exercises that influence hormones

History of Biology Research Topics

Students can consider topics related to the history of biology. They can write on the different concepts of biology such as-

  • Darwin’s theory and biology
  • Dead branches of evolution
  • History of vaccination and Edward Jenner
  • Influence of Archeology on animal biology
  • Natural Selection Theory

Obesity In House Pets

Obesity in Pets means they are overweight, and due to the excess weight, your pet can face different health issues. Did you know, maybe your love for your pet is killing your pet literally? That’s right, because of the extra treats that you give to your pet may result in extra weight. And due to this excess weight, your pet is getting pain. And this pain is because of the damages to the internal organs, joints, and bones. Here a student can take the below topics into consideration.

  • How overweight impacts the pets/
  • What are the ways to reduce weight in pets?
  • Joint disease in pets
  • Respiratory disease in dogs
  • Diabetes in cats

Ethology Research Paper Topics

Ethology term indicates the study of birds. It is one of the main biology research topics for the students. Bird behavior mainly defines or refers to the response of the bird’s action to the environmental circumstances. Some of the birds have normal behavior, and some of the bird’s behavior is learned. 

Understanding the bird’s behavior is not so difficult; it requires your time and patience. For learning the bird’s behavior, you need to start noticing the bird’s behavior. You’ll find yourself why, and how, and what they do.

Have a look at the given topics below to choose one from the different biology research topics.

  • Concepts of Ethology
  • Different theories of bird’s behavior
  • How to understand pet bird’s behavior
  • Relationship of humans with pet birds
  • How environment affect the bird’s behaviour

Camouflage Mechanism In Sea Animals

The underwater camouflage mechanism in sea animals is the set of methods of achieving crypsis. It means that sea animals remain unnoticed by the other animals in the sea, and this is observation avoidance. In water, camouflage is different from the camouflage that is on land. From all sides, the environment in the sea is the same. From the above, always light falls and trees and bushes variable backgrounds are generally not there. 

If you want to write a biology research paper, you can go for the topics from this field.

  • Methods of camouflage mechanism
  • Underwater creatures and the environment
  • Victims of sea animals
  • How camouflage helps animals to protect themselves from predators.
  • Reasons for unnatural death of sea creatures

Immunity And Stress biology research topics

Most people don’t know that the immunity of any person is also affected by stress. In our body, the cells travel through the bloodstream, and the collection of billions of these cells is called the immune system. And these cells defend our body against the antigens, such as bacteria, viruses, etc.

Some immunity and stress-related topics are-

  • Blood cells
  • How does stress affect the immunity system
  • Influence of stress on human behavior
  • Disease from stress

Asthma And Allergic Reactions

In Asthma, people face difficulties in breathing. The same allergens that cause sneezing and tearing in some people can cause Asthma in others. Normally the most common type of Asthma is allergic Asthma. About 90% of children with Asthma in children’s childhood are allergic, compared to about 50% of adults with Asthma. Check below topics for your research paper.

  • How to treat Asthma?
  • Allergic and non-allergic Asthma
  • Causes of Asthma

Marine Biology Research Topics 

Do you want to know marine biology research topics for high school students or college students? If yes, you can use the following topics.

Animal Biology Research Topics

Follow the below given current biology research topics for animals. 

Developmental Biology Research Topics

Follow the below given most popular biology research topics.

Evolutionary Biology Research Paper Topics

There are the following evolutionary biology research paper topics for students.

Molecular Biology Research Topics

Here are the following most interesting molecular research topics for the students.

Human Biology Research Topics

If you want to know the best human research topic for biology, just follow these topics.

Biology Research Paper Topics

Follow the below-given information to know the best biology research paper topics.\

Ecology Topics for Research Paper

Know the best biology topics for research topics from below.

Recent Research Topics in Biotechnology

These are the well-researched topics in biotechnology.

DNA Research Topics

These are the following DNA research topics.

  • Genetic disorders treatment
  • DNA research regarding cancer susceptibility
  • DNA-modified organisms
  • DNA as a heredity agent
  • DNA experimentation in humans
  • Ethical concerns regarding DNA-modified organisms
  • Analyzing DNA and cloning
  • How DNA structure is involved in genetic disorders
  • DNA changes versus aging
  • DNA genome sequencing

5 Tips To Pick Biology Research Topics

To choose a good biology research topic, we recommend following these general tips:

research topic in biology

Tip 1:- Conduct Complete Research

First of all, you will conduct complete research. After this, collect all the topics that you would like to choose, and just choose the best topic from all of them. But the biology research topics must be based on challenging scientific proof like chemistry research paper topics. So, once you have picked an idea, then, you should conduct primary biology research to see if there are enough relevant and reliable references or sources you could use, along with tough data, to support all your claims.

Tip 2:- Avoid General Biology Research Topics

Secondly, you should avoid general biology research topics. It is the main tip for picking a biology research paper topic. That’s ensuring it doesn’t have to do with something available. Moreover, in case, your topic is too general, you may not be capable to go into depth, which is vital for showcasing your mastering biology. The thin amount of data on a general topic might also overcome both you and your reader.

Tip 3:- Avoid Too-Narrow Research Topics Of Biology

Furthermore, you can avoid the too-narrow research topics of biology. When the research topic is too narrow, you can’t find sufficient references to write a paper. Also, your reader may become not interested as well if there’s no space for overarching queries.

Tip 4:- Research Different Biology Ideas

Moreover, you can find several topics that interest you before sifting through recent biology research papers. That’s how you’ll get a better idea of the current trends and narrow down your focus to a single topic and idea. There are tons of scholarly articles online that are available to the public.

Tip 5:- Make Sure Your Biology Research Will Derive New Discoveries

In the end, you can make sure your biology research will derive new discoveries or findings. The biology topic you pick and how you like to go about it should add value to the scientific community. So, avoid topics that can’t add anything new to the table.

Quick Links

  • Biology Branches That Are Very Important For Students
  • Importance Of Physics In Different Sectors
  • research paper help online

Now you have seen some of the main biology research topics. These biology research topics help the students a lot in the future. I hope now you are able to choose the best topic for your research paper from the above areas.

Also, if you need homework help in biology , we have a team of biology experts, you can discuss your queries with them and get the best Biology Homework Help to get A+ Grade.

What are the other biology research topics for students?

  • Genetic Engineering
  • Epidemiology
  • Climate Change
  • Endangered Species Recovery
  • Astrobiology

What factors need to be considered while choosing a biology research paper topic?

  • Consider you interest
  • Analyze the topic appropriately
  • Don’t choose too broad and too narrow topic
  • Do proper research
  • Determine your resources carefully

How to research our topic?

You can use different sources to get information about your topic. Mainly two ways are there to collect information.

  • Online sources(websites, blogs, tutorials)
  • Offline sources( books, newspapers, magazines)

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List of 225 Different Biology Research Topics

Finding research topics in biology and other interesting biology topics to research can be difficult at times, and if you’ve ever asked “what are some good biology research topics”, then this article is for you. Here are 225 different biology research topics and topics related to biology.

research topic in biology

Biology Topics to Research

Here are new biology research paper topics and biology research proposal ideas that can be chosen as research topics for biology majors. If you’re looking for good biology topics for research paper, then look no further. With this list, you never have to ask again, “what are some biology topics to write about?”

  • Prevalence of antibiotic resistance
  • Bone marrow transplants in sickle cell treatment
  • Superiority of asexual reproduction over sexual reproduction
  • Bioremediation
  • DNA evolution
  • Antibiotic resistance as a blessing
  • Splicing in treating congenital deformities
  • Superiority of sexual reproduction over asexual reproduction
  • Importance of a stable sleep cycle
  • Effects of music on neurodivergence
  • Animal regeneration
  • Adaptation in birds
  • Role of T-cells in cancer
  • How the brain recycles information
  • Negative effects of probiotics
  • Effects of potassium ash on plants
  • Transport systems in brain cells
  • Effectiveness of transport proteins
  • Flaws of transport proteins
  • Human auto-immune diseases
  • Genetic mapping of the Benjamin Button disease
  • Evolution of parasites
  • Symbiosis between fungi and trees
  • Transport system in plants
  • Effects of plant hormones on humans
  • The superiority of GMO over natural microorganisms
  • Antibiotic resistance in animals
  • Organisation in hormones
  • Allergens in vaccines
  • Innate immunity versus acquired immunity
  • Complications from grafting
  • The adaptation of memory cells
  • Treatment of osteoporosis
  • The genetics behind down syndrome
  • Signal transport throughout the CNS
  • Formation of neurones
  • How human behaviour affects animals around them
  • How human behaviour affects plants around them
  • Drug resistance as a form of evolution
  • Evolution of DNA technology in treating human diseases
  • Evolution of DNA technology in treating animal diseases
  • Application of DNA editing in treating congenital malfunctions
  • The science of neurobiology
  • Effectiveness of the paleo diet
  • Complications of human cloning
  • Cloning in animals versus plants
  • Ethical questions in human cloning
  • Usefulness of rodents in medicine
  • The effectiveness of keto diets
  • Adverse effects of sunscreen
  • Effects of ultraviolet rays on plants
  • Effects of electricity on the brain
  • Use of vibrations in regulating blood flow
  • Effects of noise pollution on foetal development
  • Effects of noise pollution on the brain
  • Hormonal causes of osteoporosis
  • Potassium and calcium in managing osteoporosis
  • The efficiency of anti-retroviral drugs
  • Rhesus factor in foetal development
  • Using the DNA as a storage device
  • Effective storage methods for DNA
  • The use of DNA in creating personalised products
  • Genetic evolution in increasing longevity
  • The use of genetics in creating personalised food
  • Ethical concerns involving GMOs
  • The use of genetics in forensic science
  • Ethical concerns over DNA-personalised products
  • Nanomaterials in the food industry
  • Nanomaterials in the cosmetic industry
  • Harmful effects of toothpaste
  • Hypersensitivity in animals
  • Effects of acid rain on vegetation
  • The benefits of biodegradable materials
  • Reaction of plants to trace elements
  • Nanotechnology in surgery
  • Effects of serotonin on the brain
  • Medical advancement in weight management
  • The placebo effect
  • Effects of lead poisoning
  • Calcicosis in young children
  • Effectiveness of homeopathy in treating illnesses
  • Reasons for calcification in the body
  • Psychological effects of dopamine
  • Impact of radio waves on foetal development
  • Immortality in jellyfishes
  • Problems of plant grafting
  • How genetics affects obesity
  • Hormones as transporters

Biology Related Research Topics

Aside from biology research proposal ideas, there are several other new biology related research topics. These topics guarantee great grades, and here are some examples.

  • The use of hypnosis in medicines
  • Relationships between birth control pills and depression
  • The ecology of marine biology
  • The occurrence of male pregnancy
  • Overgrazing in aquatic environments
  • Advancements in plant extraction technology
  • Growth enhancement in plants
  • Growing plants without soil
  • The use of fungi in accelerating plant growth
  • Causes of stress in plants
  • The link between diet and sustainability
  • How geography affects fertility
  • Food poisoning from roadside foods
  • History of Gram staining
  • Light microscope versus electron microscope
  • Etymology of the Ebola virus
  • Fundamental cloning principles
  • Congenital defects that are hereditary
  • Auto-immune diseases in animals
  • Hypersensitivity in plants
  • The use of melatonin in medicine
  • Mankind’s dependence on rainforests
  • Overdependence on synthetic products
  • How microorganisms influence depression
  • Gut microorganisms and eating disorders
  • Gene therapy in modern times
  • The body’s natural defence against cancer cells
  • Contributions of gene therapy in medicine
  • Relationship between infections and probiotics
  • Mental retardation in animals
  • Mitigating potential weaponisation of hazardous pathogens
  • Does the brain really “delete” information?
  • The REM sleep stage
  • False memories
  • How the psyche affects physical health
  • Stress and wellness
  • Neural mapping
  • Psychosocial development of infants
  • Do genes predispose aggression?
  • Genotype prediction: fact or hoax?
  • How empathy can help patients heal faster
  • Relationships between PCOS and diabetes
  • Causative factors of PCOS
  • Genetics and polycystic nephritis
  • Treatment of polycystic nephritis
  • Is PCOS a disorder of the brain?
  • Brain fog: causes, prevention and treatment
  • Insulin in PCOS treatment
  • How PCOS affects CSF and brain matter
  • Pathology of neurodegenerative diseases
  • PTSD in children
  • Dangers of Pavlovian conditioning
  • Management of polycystic nephritis
  • Downsides of immunotherapy
  • How insomnia affects the immune system
  • How hypersomnia affects the immune system
  • How antibiotics affect cells
  • The science behind food intolerance
  • Effects of electricity on plants
  • Plant adaptability
  • Animal adaptability
  • Homosexuality in animals
  • Effects of hormones on human behaviour
  • The science behind bipolar disorder
  • In vitro growing of organs
  • Problems of DNA testing
  • Genetic differences in identical twins
  • Transgenic crops: pros and cons
  • How sterile environments affect the immune system
  • Immune system malfunctions
  • Shortfalls of animal DNA modification
  • Shortfalls of human DNA modification
  • Influences of DNA on aging process
  • How climate affects biodiversity
  • Unethical uses of animals in medicine
  • Hormone-influenced psychopathy
  • Communication in plants
  • Plant sensory receptors
  • Plant-insect interactions
  • How technology protects biodiversity
  • Impact of modernisation on nature
  • Regeneration in infant brain cells
  • Nature conservation policies
  • Mutation in plasmids
  • Adaptation in microbiology
  • Predicting protein structure
  • Effects of overpopulation
  • Problems in environmental protection
  • Enzyme behaviour
  • Similarities between biochemical and chemical reactions
  • The structure of proteins
  • Effects of stress on immunity
  • Autoimmunity
  • Graft rejection
  • Modern technology and plant development
  • Hormonal therapy
  • How exercise affects hormones
  • Causes of mutation
  • Grafting in animals
  • Communication in animals
  • Organic farming
  • Effects of oil spills
  • Animal resistance mechanisms
  • Plant resistance mechanisms
  • Microbial resistance mechanisms
  • Theory of natural selection
  • Immortality in plants
  • Immortality in animals
  • The science behind hypnosis
  • Marijuana in medicine
  • Effects of antibiotics on cell structure
  • Mitosis versus meiosis
  • DNA replication
  • Axial growth in plants
  • Effects of music on termites
  • Symbiosis in insects
  • Mendelian theory
  • Theory of evolution
  • Contributions of Sigmund Freud
  • Plant sentience
  • Adaptation in aquatic organisms
  • Adaptation in arboreal organisms
  • Microbial identification
  • Test for fatty acids
  • Carbohydrate tests
  • Microfilm formation
  • Ideal enzymatic conditions
  • Common carcinogens
  • Global warming effects
  • Metagenomics
  • DNA expansion techniques
  • Astrobiology
  • Parasitism in aquatic organisms
  • Gram staining

The list above is in no way extensive in covering the topics related to biology and biology research paper topics you can write on. There are several other biology research project topics you can write on, but these comprise of research paper topics biology students, and anybody else, can choose from, for their writing.

research topic in biology

200 Distinctive Biology Research Topics to Write a Killer Paper

blog image

Biology research topics are crucial for students as they deepen their understanding of the natural world and its intricate processes.

Engaging with these topics fosters critical thinking, analytical skills, and scientific literacy.

In today’s post  our writers  have compiled a list of biology research paper topics that will help students gain access to valuable insights, up-to-date information, assisting their excellence in their academic pursuits.

This content serves as a reliable source for students to explore diverse topics and stay informed on the latest developments in the field of biology.

After reading this exciting blog post, you’ll know what to expect from a good  paper writing service . So, without further ado, let’s get started.

Table of Contents

Unique Biology Research Topics for You to Score High

Writing a research paper  on biology topics can be exciting if you know how to pick the right subject.

Stay up to date with what established biologists are studying and ensure your topic is something you can easily research and back up your ideas with.

Here’s a list of some of the most remarkable topics for an excellent college paper.

Top Biology Research Topics

  • Can drug addiction be regarded as a disease?
  • Discussing Ebola as a biological weapon.
  • How does human memory work?
  • Can we consider immortality a reality?
  • Plant diseases and their causes.
  • Analyzing if  dormant microbes trigger Alzheimer’s ? 
  • The significance of molecular biology in cancer treatment.
  • The difference between bisexuality and homosexuality in animal species.
  • How are obesity and genetics connected?
  • Understanding stem cell research.
  • How are hormones influencing the human body?
  • The most beneficial biological development in history.
  • Basic principles of human cloning.
  • Maintaining the ecosystem and its importance.
  • How are organisms adapting to challenging situations?
  • Understanding the hierarchical structure of single-celled organisms?
  • The primary function of multicellular organisms.
  • Discuss how a fossil supports the theory of evolution.
  • Understanding different cell reproduction types.
  • Reasons why enzymes are essential.
  • Difference between eukaryotes and prokaryotes.
  • The process of photosynthesis.
  • How does human metabolism work?
  • The difference between mitosis and meiosis.
  • Probability of gene inheritance.
  • Understanding the DNA Structure.
  • How is PCR used?
  • The mechanism of cloning.
  • Discussing the carbon cycle mechanisms.
  • Effects of humans on biodiversity.
  • Main factors regulating the dynamics of a population.
  • The modern relatives of dinosaurs.
  • Strategies organisms use for acquiring nutrition.
  • The tree of life.
  • Understanding the concept of natural selection.

As time progresses, biologists are increasingly exploring  animal research topics  in addition to human studies. These subjects encompass investigations into animal evolution, existence, and survival. 

By delving into these areas, researchers comprehensively understand the intricate relationships between various species and their environments, ultimately enhancing our knowledge of the natural world.

Unique Biology Research Topics

Every day, the world of science uncovers new discoveries, with dedicated researchers continuously embarking on medical expeditions.

These efforts have led to the identification of numerous  autism research topics , significantly enhancing our understanding of this complex condition.

As a result, these findings have greatly benefited the field of  special education research , paving the way for improved support and tailored interventions for individuals with autism.

By staying informed on the latest advancements, we can collectively contribute to a more inclusive and empathetic society.

If you want your paper to stand out, pick one of these great research topics for your biological research!

  • The role of cells in healing damaged bones.
  • The right amount of protein to consume.
  • Effects of cancer on growth cells.
  • Is it ethically good to research stem cells?
  • Different ways in which cells communicate.
  • How are DNA and the environment connected?
  • Recent developments in cell biochemistry.
  • Can you reverse the process of aging?
  • How are cilia facilitating the cells’ movement?
  • Reasons why cells get sticky.
  • Understanding how the brain keeps memories.
  • Is surgery the only way of treating glaucoma?
  • Understanding protein biosynthesis process.
  • The central dogma of molecular biology – what must you know?
  • Understanding diffusion as a transport technique.
  • The role of microtubules in the nervous system.
  • Ways to improve hypertrophy in the body.
  • The impact of sunburns.
  • The effects of music on the brain.
  • How is learning affected by the sleep and wake cycles?
  • Is drinking more water could prevent extensive sunburns? 
  • The effects of sunlight on biomass.

Easy Biology Research Paper Topics

If you are new to the field of biology, then you can start looking at this list of easy biology research topics.

  • The process of tissue formation.
  • Reasons for the existence of different congenital disabilities.
  • Existing HIV drugs and their complexities.
  • Why does chemotherapy fail for some patients?
  • The effect of germs on the cells.
  • How does the sun affect the skin?
  • Why can’t we treat some diseases with drugs?
  • Ways to treat animals that are carrying the virus.
  • Discuss the five animals in extinction.
  • Why should people care for endangered species?
  • Can humans sustain a plant-based diet?
  • The inconveniences of space travel.
  • The emergence of leukemia.
  • Understanding the human immune system.
  • Factors responsible for weakening the immunological system.
  • The origin and consequences of autoimmune.
  • How immune disorder affects the human body.
  • Effectiveness of vaccines in eradicating a disease.
  • Complexities of taking the Hepatitis B vaccine.
  • Why do humans have allergies?
  • How does DNA modification work?
  • Common misconceptions about COVID-19.

Interesting biology research topics

Looking into biology can be super fun – many cool topics exist. High school and college students can find something that interests them, whether a common topic relevant to the community or something more fascinating. It’s worth checking out!

  • Effects of marijuana and alcohol on teenagers.
  • How is alcohol affecting teenagers and adults?
  • How is neuroscience helpful in coping with emotional pain?
  • How does the brain process speech?
  • Factors that are responsible for autism.
  • Is it true that a human is an animal?
  • The effect of isolation on the human brain.
  • Factors contributing to automatic responses.
  • How is noise pollution affecting living organisms?
  • Understanding the fire ecology.
  • Understanding the term bioremediation.
  • What should we know about urban ecology?
  • Is excessive internet usage damaging to human memory?
  • Understanding the infectious-disease-causing agents.
  • The importance of cancer research.
  • Why is genetic engineering a challenge?
  • The role of melatonin in therapy.
  • Are hormones responsible for risky behavior?
  • What is the latest research on stem and cloning?
  • Physical activities and their role in hormone development.
  • Transgenic crops – benefits and threats.
  • Analyzing the fight against smallpox.
  • The future of prosthetic appliances.
  • Examining mind-controlled limbs.
  • Is cosmetic surgery a need?
  • The significance and process of vascular surgery.
  • Analyzing trends in biomedicine.
  • The functions of X-rays.
  • The most effective way of preserving wildlife.
  • Poverty and its contribution to climate hazards.
  • Analyzing how a human body reacts to poison.
  • The misconceptions about sexually transmitted diseases.
  • The significance of understanding evolutionary biology.

Good biology research topics

If you’re looking for an exciting biology research paper topic, try and find one that offers an unexpected angle on life.

It should be engaging, captivating, and relevant to the world. It’s all about exploring a subject with lots of potential and can help us better grasp life and living organisms.

Here’s another list of great topics for your biology research.

  • Understanding quantitative ecology.
  • The causes of acidification of seas and its consequences.
  • Immortality of jellyfish.
  • The difference between seawater and freshwater.
  • The evolution of the deep sea.
  • The communication techniques of whales.
  • Coral reefs and their importance to seawater.
  • The effects of tourism on natural animal habitats.
  • Is it possible to domesticate wild marine animals?
  • The pros and cons of living in the coastal zone.
  • The survival of plants in the sea.
  • Analyzing two different species of animals in the water.
  • Ways to generate and use marine energy.
  • Molecular genetics and its ethical considerations.
  • Understanding the structure of the gene.
  • Analyzing restrictions in the DNA.
  • Examining the building blocks of life.
  • Understanding why prion disease is so dangerous.
  • Dominant genes vs. recessive genes.
  • Is there a possibility of human DNA getting damaged?
  • What is the objective of nucleic acid?
  • How to cope with the challenge of animal extinction
  • Things we should know about sea life.
  • The history of genetics.
  • How has the lockdown affected social interaction?
  • Reasons behind some people refusing the vaccine.
  • Is animal hunting a fashion or a need?
  • The evolution of a virus.
  • What does invasive species mean?
  • Is life on Mars Possible?
  • Understanding the term’ herd immunity.’
  • How are biology and archaeology related?
  • What should we know about natural selection?
  • The dead branches of evolution.
  • The present trends of whale hunting.

Biology research topics related to cells and more

Advances in cell biology can help treat illnesses and wipe out viruses. Crafting a paper on this topic can be a satisfying experience for any biology student. Here you go with some interesting topics related to cells and more.

  • The effects of gut bacteria on the brain.
  • Ethical concerns around organ transplant.
  • How does alcohol affect the liver?
  • Is obesity related to genetics?
  • Why do we need genetically modified foods?
  • Sun exposure and its effect on the human skin.
  • Is it correct to say that depression is hereditary?
  • How is music influencing the human brain?
  • The latest trends in forensic DNA.
  • The importance of nanotechnology in the treatment of HIV.
  • Understanding how humans consume food.
  • Challenges that technology is posing to human health.
  • The most common cell infections.
  • The structure of the animal cell.
  • The role of cell biology in treating Alzheimer’s disease.
  • Identifying the characteristics of viruses.
  • The difference between RNA and DNA.
  • The hormonal control system of mammals.
  • Factors that speed up the metabolism.
  • Understanding hormonal malfunctioning.
  • The structure of digestive systems.
  • The importance of the sun as an energy source for cells.
  • Size and function of Eukaryotic and Prokaryotic cells.
  • Cell membranes and their importance.
  • How are DNA and RNA different?
  • Importance of cell biology in understanding genetics.
  • Understanding the molecular energy reserves.
  • The significance of apoptosis for growth.
  • How impactful are defective cells for the normal functioning of the body?
  • The relationship between cell function and cell structure.
  • How are cytokines and cell biology related? 

Excellent Biology Research Topics

Still on the hunt for top-notch topics for your biology research paper? Check out this list; it has some great research topics for you to consider.

  • Global warming and its biological impact.
  • Factors affecting population genetics.
  • Oxytocin and its role in the human reproductive system.
  • The functioning of the human immune system.
  • Effective ways to deal with stress biology.
  • Common causes of asthma.
  • The effect of transplantation on the human immune system.
  • Perception of vaccination in society.
  • The properties of well-functioning human cells.
  • Restricting enzymes and their importance in body functionality.
  • The role of neurobiology in improving human memory.
  • Different chemical reactions in the human body.
  • The evolution of biology.
  • The main reasons for plant diseases and how to cure them?
  • The phenomenon of homosexuality and bisexuality.
  • Biodiversity and climate change.
  • How physical exercises can impact metabolism.
  • Bacteria and its effect on depression.
  • The adverse effects of rainforest extinction.
  • Ways of mapping and cloning genes.
  • The adverse effects of the oligogenic disease.
  • Hereditary diseases and their danger.
  • The cognitive functions of primates.
  • Down syndrome and its leading causes.
  • Probiotics and their role in curing infections.
  • Main reasons for obesity in pets.
  • The pros and cons of testing beauty products on animals.
  • A case study on the biology of marine birds.

New and Trendy Biology Research Topics

It’s a good idea to keep up with the times when writing a biology research paper, so here’s a list of some of the hottest biology topics right now.

  • Understanding genetic drift.
  • The complex process of DNA Replication.
  • The importance of neurobiology.
  • Is genetic engineering a way to cure obesity?
  • Does age slow our reaction time?
  • Bipolar disorder – what do we need to know?
  • Hormones and their effect on our behavior.
  • Should human cloning be legalized?
  • The advantages of vaccination.
  • Is it correct that bees are becoming extinct?
  • The unique biology of marine birds.
  • Understanding the extracellular matrix.
  • Differences between warm-blooded and cold-blooded animals?
  • The existence and evolution of arthropods.
  • Annelids and their characteristics.
  • The evolution of reptiles.
  • Ways to prevent genetic diseases.
  • Genetic testing and its ethical implications.
  • Is DNA helpful in solving crimes?
  • The role of antibiotics in controlling diseases.
  • How effective is bone marrow transplant in treating sickle cell?
  • Probiotics and their harmful effects.
  • What factors cause stress in plants?
  • The psychological development of infants.
  • Parasites and their evolution.
  • Sunscreen and its adverse effects.
  • The harmful effects of toothpaste you should know.
  • The biological basis of psychological disorder.
  • The recent development of oxytocin science.
  • The importance of cardio exercises.
  • The significance of therapeutic cloning.
  • The benefits of organic farming.
  • Understanding DNA testing.
  • Analyzing the impact of steroids.
  • The role of neuroscience in robotic technology.
  • Ways to deal with the problem of extinction.
  • Genetic factors that influence the immunological system.
  • Understanding the neurobiological explanation of sleep.
  • The phenomenon of DNA-modified organisms.
  • The evolution of infectious diseases.
  • Pollution and its impact on people.

You now have a good idea of what biology research topics you want to explore, right? Check what your professor is expecting and then contact our experts if you have a problem dealing with this assignment yourself. 

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569 Biology Research Topics & Cool Ideas

18 January 2024

last updated

Biology research topics include many aspects of living beings, from molecular interactions to ecosystem dynamics. Some themes delve into the secrets of genetics, studying the subtle dance of DNA and RNA to understand heredity and mutation. Other topics cover the realm of microbiology, examining bacteria, viruses, and fungi that are essential to life and yet can cause disease. In neuroscience, people can explore the brain’s complex networks, probing consciousness and memory. Ecological research illuminates the delicate balance of life on the planet, investigating species interactions, climate change impacts, and conservation strategies. Cell biology research uncovers the inner world of the cells, elucidating various processes, such as protein synthesis, cell division, and signal transduction. Therefore, biology research topics form the core concepts of how the biological world works, a field forever expanding human understanding of life in all its beautiful complexity.

Good Biology Research Topics

  • Cellular Respiration and Energy Conversion Mechanisms
  • Protein Structure and Its Influence on Function
  • Epigenetics: An Exploration of Hereditary Changes
  • Plant Defense Mechanisms Against Pathogens
  • Circadian Rhythms in Humans and Animals
  • Neural Plasticity and Cognitive Function
  • Studying Gene-Environment Interactions in Disease
  • Bacterial Resistance to Antibiotics
  • Human Microbiome: Implications for Health
  • Regulation of Cell Growth and Cancer
  • Ecology of Invasive Species
  • Investigation Into Prion Diseases
  • Plant Photosynthesis and Climate Change
  • Deciphering the Human Genome
  • Genetic Basis of Behavioral Traits
  • Stem Cells: Potential and Limitations
  • Immunology: Unraveling Allergic Responses
  • Ocean Acidification and Marine Life
  • Probiotics and Gut Health
  • Epigenetic Factors in Aging

Biology Research Topics & Cool Ideas

Easy Biology Research Topics

  • Understanding Photosynthesis: The Green Magic
  • Investigating the Life Cycle of a Butterfly
  • Bird Migration Patterns and Causes
  • Life in a Drop: Exploring Pond Microorganisms
  • Exploring Darwin’s Theory of Natural Selection
  • Mendel’s Laws: Studying Genetics in Pea Plants
  • Food Chains and Energy Flow in Ecosystems
  • Cell Structure: Uncovering the Building Blocks of Life
  • Human Digestive System: From Bite to Nutrient
  • How Does DNA Replication Work?
  • Circulatory System: A Journey Through the Human Body
  • Mushroom Lifecycle: An Investigation
  • Tree Rings Tell a Story: Dendrochronology Basics
  • Understanding the Human Eye: Vision Mechanics
  • Adaptations: How Do Animals Survive in the Arctic?
  • Coral Reefs: An Ecosystem Underwater
  • Flower Pollination: The Work of Bees
  • Why Do Leaves Change Color in Autumn?
  • Mitosis: The Process of Cell Division

Interesting Biology Topics

  • Symbiotic Relationships in Nature
  • Mysteries of Bioluminescence
  • Pandemics: Influenza and Beyond
  • Neuroplasticity: Brain’s Adaptability
  • Venomous Creatures and Their Defense Mechanisms
  • Fermentation Process in Brewing
  • Epigenetics: Beyond the DNA Sequence
  • Journey Into the Human Genome
  • Biodiversity in the Rainforest
  • Life at the Extremes: Organisms in Deep Sea Vents
  • Biomimicry: Nature’s Design Genius
  • Invasive Species: Consequences and Control
  • Plant Communication: More than Meets the Eye
  • Stem Cells: Hope and Hype
  • Human Microbiome: We Are Not Alone
  • Camouflage and Mimicry in Nature
  • Circadian Rhythms: The Body’s Internal Clock
  • Probiotics: Beneficial Microorganisms
  • Endangered Species: Conserving Biodiversity
  • Cloning: Ethical and Biological Considerations

Biology Research Topics for High School

  • Genetics and Inheritance Patterns
  • Photosynthesis: Life’s Solar Panel
  • Cell Division: Mitosis and Meiosis
  • Human Immune System: Body’s Defense
  • Ecology: Ecosystems and Food Webs
  • Exploring the Animal Kingdom
  • Plant Life: From Seed to Flower
  • Bird Migration Patterns
  • Endocrine System: Hormones at Work
  • Aquatic Biomes: Life Underwater
  • Genetic Engineering: Pros and Cons
  • Taste and Smell: Sensory Biology
  • Principles of Evolution
  • Nutrition and Digestion
  • Biotechnology and Its Applications
  • Human Brain: Anatomy and Function
  • Mitochondria: Powerhouse of the Cell
  • Aquatic Pollution: Effects on Marine Life
  • Disease Transmission: Viruses and Bacteria
  • DNA and RNA: The Code of Life

Biology Research Topics for College Students

  • Biological Effects of Climate Change
  • Neurobiology of Sleep and Circadian Rhythms
  • Behavioral Ecology: Studying Animal Behavior
  • Nanotechnology in Biology
  • Understanding Human Aging Process
  • Stem Cells and Regenerative Medicine
  • Exploration of Marine Biodiversity
  • Ecological Impact of Invasive Species
  • Cancer Biology: Mechanisms and Treatments
  • Symbiosis in Nature: A Detailed Study
  • Molecular Biology of Prions
  • Biodiversity and Conservation
  • Bioinformatics: Analyzing Biological Data
  • Plant Genetic Engineering for Food Security
  • Biochemistry of Metabolism
  • Developmental Biology: From Zygote to Organism
  • Neuroscience: Understanding the Human Brain
  • Protein Structure and Function

Biology Research Topics for University

  • Human Genomics: Decoding Our DNA
  • Molecular Mechanisms of Diseases
  • Microbiology of Extreme Environments
  • Neuroplasticity and Learning
  • Antibiotic Resistance: A Growing Threat
  • Plant Responses to Environmental Stress
  • Paleobiology: Reading Fossils for Evolutionary Patterns
  • Nanomedicine: Opportunities and Challenges
  • Advanced Immunology: Understanding Immune System
  • Cellular Mechanisms of Aging
  • Parasitology: Life Cycle and Host Interaction
  • Bioengineering: Bridging Biology and Technology
  • Comparative Anatomy: Insights Into Evolution
  • Endocrinology: Hormones and Health
  • Biology of Sex and Gender
  • Bioluminescence in Marine Organisms
  • Understanding Genetic Disorders
  • Molecular Virology: Viruses and Host Interactions
  • Genetics of Human Population Variation
  • Microbial Ecology: Microbes in Ecosystems

Human Biology Research Topics

  • Human Brain Mapping: Unraveling the Mysteries
  • Genetic Basis of Human Diseases
  • Stem Cells: Promise and Challenge in Medicine
  • Epigenetic Modifications in Human Health and Disease
  • Aging Process: Cellular and Molecular Mechanisms
  • Biotechnology in Human Reproduction
  • Neuroendocrinology: Interactions of Brain and Hormones
  • Genomics and Personalized Medicine
  • Environmental Influences on Human Health
  • Challenges in Transplantation Biology
  • Physiological Basis of Human Nutrition
  • Molecular Basis of Human Cancer
  • Immunotherapy: New Frontiers in Treatment
  • Genetic and Environmental Factors in Obesity
  • Deciphering the Human Microbiome
  • Longevity and Lifespan Extension
  • Circadian Rhythms in Human Biology
  • Biological Markers in Neuropsychiatry
  • Pathogenesis of Autoimmune Diseases
  • Metabolic Syndrome: Interconnected Health Issues

Immune System Biology Topics to Research

  • Deciphering the Role of Innate Immunity in Autoimmune Diseases
  • Impact of Aging on Adaptive Immune Response
  • Toll-Like Receptors and Their Contribution to Immune Defense
  • Unveiling the Mystery of Immunological Memory
  • Immuno-Oncology: Unraveling the Cancer-Immune System Battle
  • Exploring the Complex World of Major Histocompatibility Complex (MHC)
  • Intricate Interplay of Cytokines in Inflammatory Responses
  • Harnessing Natural Killer Cells in Immunotherapy
  • Role of Complement System in Immune Response and Disease
  • Influence of Stress and Mental Health on Immune Functionality
  • Antibody Diversity: Generation and Its Clinical Implications
  • Immune Evasion Mechanisms Employed by Pathogens
  • Unraveling the Biology of Regulatory T Cells
  • Inflammatory Bowel Disease: An Immune System Conundrum
  • Vaccines: Illuminating the Principles of Immune Activation
  • Autoimmunity and Gender: Understanding the Female Predominance
  • Dendritic Cells: Guardians of Immunity
  • Role of Epigenetics in Immune Cell Differentiation
  • Thymus and T Cell Maturation: An In-Depth Study
  • Role of Nutrition in Modulating Immune Responses
  • Unfolding the Link Between Allergies and the Immune System

Genetics Research Topics in Biology

  • Genetic Algorithms: Explorations and Applications
  • Epigenetics: Beyond the Human Genome
  • Biodiversity and Genetic Conservation
  • Gene Therapy: Ethical and Safety Concerns
  • Molecular Mechanisms of Genetic Mutations
  • Neurogenetics and Disorders of the Nervous System
  • Pharmacogenomics: Personalizing Drug Therapy
  • Transposable Elements in Genome Evolution
  • Gene-Environment Interactions in Disease
  • Genetics of Aging and Longevity
  • Genome Editing Technologies and Implications
  • Prenatal Genetic Screening and Diagnosis
  • Human Behavioral Genetics: Nature vs. Nurture
  • Cancer Genomics: Unlocking the Disease Code
  • Forensic Genetics: DNA Evidence in Crime Solving
  • Genetic Basis of Infectious Diseases
  • Gene Regulation in Development and Disease
  • Genetic Engineering: Prospects and Perils
  • Population Genetics: Understanding Genetic Variation
  • Genomics of Complex Traits and Diseases

Neurobiology Research Topics

  • Molecular Mechanisms of Memory Formation
  • Brain-Computer Interfaces: Bridging Neurology and Technology
  • Neuroplasticity and Learning Adaptations
  • Neuroimmunology: Immune Response in Neurological Disorders
  • Neurobiology of Aging and Age-Related Disorders
  • Neurochemical Correlates of Mental Disorders
  • Decoding Neural Networks in Cognitive Function
  • Genetic Influences on Neurodevelopmental Disorders
  • Cellular Mechanisms of Sensory Perception
  • Neurobiology of Pain: Unraveling Chronic Conditions
  • Addiction Pathways in the Neurobiological Context
  • Exploring the Biological Basis of Consciousness
  • Neuroprosthetics and Their Clinical Implications
  • Understanding Neurogenesis in Adult Brain
  • Regenerative Medicine in Neurological Diseases
  • Neural Circuitry and Emotion Regulation
  • Neurobiology of Stress Effects on the Brain
  • Neuroanatomy of Language and Communication Disorders

Evolutionary Biology Research Topics

  • Speciation Mechanisms in Endemic Species
  • Epigenetic Inheritance: A New Dimension in Evolution
  • Adaptive Radiation in Island Ecosystems
  • Sexual Selection and Animal Behavior
  • Microbial Co-Evolution and Antibiotic Resistance
  • Genomics and Phylogenetics: Tracing Life’s History
  • Evolutionary Medicine: Disease and Natural Selection
  • Allopatric Speciation in Geographically Isolated Populations
  • Paleogenomics: Reconstructing Evolutionary History
  • Ecological Genomics and Adaptive Evolution
  • Evolutionary Bioinformatics: Decoding Life’s History
  • Mimicry and Camouflage in Animal Kingdom
  • Comparative Genomics in Evolutionary Studies
  • Hominin Evolution: Tracing the Origins of Homo Sapiens
  • Plant Evolution in Response to Environmental Stress
  • Genetic Drift and Population Bottlenecks
  • Evolutionary Ecology of Host-Parasite Interactions
  • Molecular Phylogenetics and Species Divergence
  • Selection Pressures in Pathogen Evolution

Research Topics in Biological Crossing

  • Artificial Selection and Genetic Improvement
  • Genetic Hybridization in Agriculture
  • Transgenic Organisms: Methods and Implications
  • Meiosis and Genetic Recombination
  • Horizontal Gene Transfer in Bacteria
  • Inbreeding Depression and Heterosis
  • Cytoplasmic Inheritance in Plant Breeding
  • Interactions of Crossing Over and Linkage
  • Ethics and Biotechnology: GMOs in Focus
  • Genome Editing Techniques: CRISPR and Beyond
  • Selective Breeding and Animal Husbandry
  • Interspecific Hybridization and Speciation
  • Chromosomal Aberrations During Crossing
  • Synthetic Biology: Creating Life in the Lab
  • Next Generation Sequencing and Genomic Diversity
  • Bioinformatics in Genomic Research
  • Regulation of Meiotic Recombination in Eukaryotes
  • Genetic Markers in Plant Breeding
  • Chromosomal Mapping and Linkage Analysis
  • Genome-Wide Association Studies in Complex Traits

Topics on Prohibited Research in Biology

  • Ethical Dilemmas in Cloning
  • Human Genetic Modification and Society
  • Legalities Surrounding Stem Cell Research
  • Chimeras: Genetic Engineering Boundaries
  • Biohacking and Personal Genetic Engineering
  • Euthanasia: Perspectives in Biological Sciences
  • Dual Use Research of Concern (DURC) in Microbiology
  • Creating Novel Pathogens: Scientific Gain or Risk?
  • Human-Animal Embryo Research: Crossing the Line?
  • Biopiracy and Exploitation of Indigenous Knowledge
  • Brain-Computer Interfaces: Privacy and Consent Issues
  • Eugenics and Genetic Discrimination
  • Designer Babies: Possibilities and Ethical Challenges
  • Artificial Wombs: Ethical and Legal Considerations
  • Genetically Modified Crops: Ecological Concerns
  • Animal Testing in Biomedical Research
  • Age Reversal Experiments: Ethical Quandaries
  • Synthetic Viruses and Biological Weapons
  • Genetic Privacy in the Age of Personal Genomics

Topics on Experimental Research in Biology

  • Pioneering Techniques in CRISPR-Cas9 Gene Editing
  • Immunotherapy and Personalized Medicine Advances
  • Experimental Designs for Microbiome Studies
  • Single Cell RNA Sequencing Techniques and Applications
  • In Vivo Models for Alzheimer’s Disease
  • Investigating Symbiotic Relationships in Marine Biology
  • Advancements in Bioluminescence Imaging Techniques
  • Metabolic Pathways in Cancer: Experimental Approaches
  • Investigating Brain Plasticity in Adult Mammals
  • Strategies for Genome-Wide Association Studies
  • Experimental Approaches to Studying Epigenetics
  • Nano-Biotechnology: Novel Techniques and Applications
  • Optogenetics in Neural Circuit Analysis
  • In Vitro Fertilization: Advancements and Challenges
  • Experimental Methods in Protein Folding Studies
  • Techniques in Cellular Reprogramming
  • Approaches in Tissue Engineering and Regenerative Medicine
  • Neuroimaging Techniques in Cognitive Neuroscience
  • Experimental Models for Studying Zoonotic Diseases
  • Techniques and Challenges in 3D Bioprinting

Topics to Research on DNA

  • Novel Insights Into DNA Repair Mechanisms
  • Epigenetic Modifications in DNA Methylation
  • DNA Barcoding and Biodiversity Studies
  • Understanding DNA Replication Fidelity
  • Whole Genome Sequencing: Techniques and Applications
  • DNA Damage Response in Aging Cells
  • Nanotechnology Approaches for DNA Sequencing
  • Single Molecule Studies of DNA Replication
  • Comparative Genomics and DNA Conservation
  • Structural Studies of DNA-Protein Interactions
  • Mechanisms of DNA Recombination
  • CRISPR-Cas9 and DNA Editing Advances
  • DNA Topology in Cellular Functions
  • DNA-Based Therapies for Genetic Disorders
  • Bioinformatics Tools for DNA Sequence Analysis
  • DNA Fingerprinting in Forensic Science
  • Origin and Evolution of Mitochondrial DNA
  • Microsatellites and DNA Polymorphism
  • Techniques in DNA Data Storage
  • DNA Vaccines and Immunotherapies

Biology Topics to Research on Behavior and Hormones

  • Behavioral Endocrinology: Hormones and Social Behavior
  • Neuroendocrine Regulation of Aggression
  • Circadian Rhythms and Hormonal Regulation
  • Impact of Stress Hormones on Animal Behavior
  • Hormones and the Development of Parental Behavior
  • Adrenal Hormones and Fear Response Mechanisms
  • Hormonal Influences on Human Sexual Behavior
  • Behavioral Implications of Hormonal Imbalances
  • Influence of Hormones on Eating Behavior
  • Gonadal Hormones and Mood Disorders
  • Endocrine Disruptors and Altered Behaviors
  • Hormonal Control of Migration in Birds
  • Hormones and Memory Formation: Neurobiological Perspectives
  • Thyroid Hormones and Behavioral Development
  • Pheromones and Reproductive Behaviors
  • Serotonin, Dopamine, and Behavior
  • Oxytocin’s Role in Social Bonding
  • Growth Hormones and Aging Behavior
  • Insulin and Behavior: Beyond Metabolic Regulation

Cell Biology Topics to Research

  • Unraveling the Mysteries of Mitochondrial DNA
  • Decoding the Language of Cell Signaling
  • Cellular Mechanisms in Autophagy
  • Exploring the Intricacies of Cell Death: Apoptosis vs. Necroptosis
  • Understanding Mechanotransduction: How Cells Sense Mechanical Stress
  • Navigating the Maze of the Cell Cycle: Checkpoints, Progression, and Control
  • Molecular Choreography of Chromosome Segregation
  • Epigenetic Modifications and Cellular Memory
  • Unpacking the Secrets of the Nucleolus
  • The Curious Life of Lysosomes: Beyond Waste Management
  • Enigmatic Endoplasmic Reticulum: Functions and Pathways
  • Cellular Journey: Endocytosis and Exocytosis Mechanisms
  • Wnt Signaling Pathway: Critical Regulator of Cell Fate
  • Deciphering the Role of Actin in Cell Motility
  • Delving Into the World of Nuclear Pore Complexes
  • Investigating the Role of Golgi Apparatus in Protein Trafficking
  • Unfolding the Mystery of Protein Folding in Cells
  • Dissecting the Details of the DNA Replication Process
  • Uncovering the Dynamic World of Cytoskeleton

Molecular Biology Research Topics

  • Decoding the Language of RNA Splicing
  • Unraveling Introns and Exons: The Puzzle of Gene Expression
  • Translation Process: Uncovering Ribosome Secrets
  • Diving Into Telomeres: Maintaining Genomic Integrity
  • Long Non-Coding RNAs: Genomic Dark Matter Illuminated
  • Genome Organization: A Peek Into Chromatin Architecture
  • Understanding DNA Methylation and Its Implications
  • MicroRNAs: Small Molecules, Big Functions
  • Transposable Elements: Jumping Genes and Genome Evolution
  • Unveiling the Mystery of DNA Repair Mechanisms
  • Revisiting the Central Dogma: From DNA to Protein
  • RNA Interference: The Silence of Genes
  • Mechanisms and Models of Genetic Recombination
  • Unraveling the World of Quorum Sensing in Bacteria
  • Understanding the Intricacies of Signal Transduction
  • Post-Translational Modifications: The Final Touch in Protein Synthesis
  • Decoding the Processes of Protein Degradation
  • Nuclear-Cytoplasmic Transport: Moving Molecules Across the Cell
  • Unpacking the Enigma of Prions: Infectious Proteins

Plant Pathology Research Topics

  • Unraveling Plant-Virus Interactions: A Molecular Approach
  • Plant Defense Mechanisms Against Pathogenic Bacteria
  • Decoding Fungal Pathogenesis in Crops
  • Molecular Insights Into Plant-Insect Interactions
  • Nematodes and Plant Health: A Detailed Study
  • Signaling Pathways Involved in Plant Immunity
  • Phytoplasma-Plant Interactions: Understanding the Pathogenesis
  • Biocontrol Agents in Combating Plant Diseases
  • Mechanisms of Plant Resistance to Fungal Pathogens
  • Exploring the World of Oomycetes: Plant Destroyers
  • Host Specificity in Plant Pathogens: A Deep Dive
  • Unraveling the Mystery of Mycotoxins in Plants
  • Plant Proteases and Their Function in Disease Resistance
  • RNA Silencing in Plants: Defense Against Viruses
  • Plant Pathogenic Bacteria: Unveiling the Mode of Infection
  • Phytoalexins: A Key Player in Plant Immunity
  • Deciphering the Role of Plant Hormones in Disease Resistance
  • Emerging Diseases in Crop Plants: A Global Overview
  • Studying the Influence of Climate Change on Plant Diseases

Ecology Research Topics

  • Understanding Species Interactions and Ecosystem Dynamics
  • Climate Change and Biodiversity Loss: A Comparative Study
  • Interplay Between Microbial Communities and Ecosystem Processes
  • Invasive Species and Ecosystem Disruption: A Closer Look
  • Sustainable Agricultural Practices and Their Effect on Ecosystem Health
  • Examining Trophic Cascades in Aquatic and Terrestrial Ecosystems
  • Biomonitoring and Its Significance in Conservation Biology
  • Endangered Species Protection: Investigating Successful Strategies
  • Biosphere Reserves and Their Contribution to Ecosystem Stability
  • Fire Ecology: Unraveling the Effects of Wildfires on Ecosystems
  • Marine Protected Areas and Their Significance in Ocean Health
  • Exploring Ecosystem Services: From Pollination to Carbon Sequestration
  • Landscape Ecology: Understanding Land Use Changes and Biodiversity
  • Ecology of Urban Environments: Challenges and Solutions
  • Ecological Succession: Understanding Changes in Ecosystem Over Time
  • Fragmentation of Habitats: Causes, Effects, and Mitigation Strategies
  • Pollution Ecology: Tracing the Effects of Contaminants on Ecosystems
  • Ecology of Zoonotic Diseases: From Wildlife to Humans
  • Alpine Ecosystems: A Study in Climate Sensitivity and Adaptation

Marine Biology Research Topics

  • Exploring Deep-Sea Biodiversity and Its Conservation
  • Conservation Strategies for Marine Protected Areas
  • Understanding Coral Reef Dynamics and Resilience
  • Ocean Acidification: Causes and Effects on Marine Life
  • Cetacean Behavior and Communication Systems
  • Unraveling Mysteries of Marine Bioluminescence
  • Marine Biofouling: Understanding the Mechanisms and Finding Solutions
  • Investigating Plastic Pollution in the Oceans: From Microplastics to Ghost Nets
  • Jellyfish Blooms: Causes, Consequences, and Controls
  • Assessing the Threats to Seagrass Meadows
  • Understanding the Ecology of Hydrothermal Vents
  • Shark Conservation: Challenges and Opportunities
  • Effects of Sonar and Noise Pollution on Marine Mammals
  • Marine Microplastics: Their Role in the Marine Food Web
  • Invasive Marine Species: Mechanisms and Management
  • Deep Sea Mining: Ecological Consequences and Mitigation
  • Marine Parasites: Life Cycles, Host Interactions, and Ecology
  • Exploring the Ecology of Mangrove Ecosystems
  • Unraveling the Secrets of Marine Symbiotic Relationships
  • Decoding the Language of Dolphin Communication

History of Biology Research Topics

  • Understanding Linnaeus: His Contribution to Biological Classification
  • From Alchemy to Biochemistry: Tracing the Historical Path
  • Decoding the Double Helix: Discovery of DNA Structure
  • Voyage of HMS Beagle: Darwin’s Journey and Its Implications
  • Development of Modern Microscopy and Its Influence on Cell Theory
  • Louis Pasteur and the Fight Against Infectious Diseases
  • Fleming’s Accidental Discovery: The Advent of Antibiotics
  • Mendel’s Peas: The Birth of Genetics
  • In the Footsteps of Gregor Mendel: The Expansion of Genetic Studies
  • Exploring the Origins of Molecular Biology
  • History of Biotechnology: From Yeast Fermentation to Genetic Engineering
  • Dolly the Sheep: A Historical Perspective on Cloning
  • Biological Warfare: An Analysis From Ancient Times to Modern Day
  • From Eugenics to Modern Genetics: A Controversial History
  • Endosymbiotic Theory: Tracing the Origins of Mitochondria and Chloroplasts
  • Nobel Prizes in Biology: Insights Into Scientific Progress
  • Understanding the History of Genetic Engineering
  • Vaccination: A Historical Perspective From Smallpox to Covid-19
  • Unraveling the Human Genome Project: A Historical Approach
  • Rosalind Franklin and the Unseen Contributions of Women in Biology

Animals Biology Research Topics

  • Comparative Analysis of Neural Networks in Echolocating Bats and Dolphins
  • Potential Applications of Biofluorescence in Marine Organisms
  • Genomic Adaptations in High Altitude Birds: A Deep Dive
  • Microbiome Influence on Mammalian Health and Behavior
  • Biodiversity Conservation Strategies in Tropical Rainforests
  • Understanding Bioluminescence: From Fireflies to Deep Sea Creatures
  • Climate Change Effects on Polar Bear Migration Patterns
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  • Intricate Courtship Behaviors of Birds of Paradise
  • Survival Strategies of Desert Dwelling Species
  • Behavioral Plasticity in Social Insects
  • Species Survival in the Midst of Habitat Fragmentation
  • Exploring Symbiosis: Coral Reefs and Their Resident Microorganisms
  • Adaptation Mechanisms of Alpine Flora and Fauna
  • Communication Strategies among Cephalopods
  • Antarctic Krill: A Keystone Species in a Changing Environment
  • Tracking Migration: Navigational Abilities of Monarch Butterflies
  • Investigating Tool Use in Cetaceans
  • Molecular Mechanisms Behind Poison Production in Venomous Creatures

Zoology Research Topics

  • Animal Camouflage: Unraveling the Mechanisms Behind Crypsis
  • Conservation Strategies for Endangered Amphibian Populations
  • Dynamics of Social Hierarchies in Primate Groups
  • Mechanisms of Venom Production in Conus Snails
  • Assessing Biodiversity in Deep Sea Ecosystems
  • Nutrient Cycling in Detritivore Communities
  • Signal Transduction in Echolocating Mammals
  • Flight Adaptations in Migratory Bird Species
  • Uncovering the Secrets of Bioluminescence in Cnidarians
  • Hibernation Patterns in Arctic Mammals
  • Endocrine Disruption in Aquatic Invertebrates
  • Territorial Behavior among Canine Species
  • Parasite-Host Interactions in Marine Ecosystems
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  • Investigating Cooperative Behavior in Social Insects
  • Adaptations of High-Altitude Wildlife to Hypoxia
  • Understanding Reproductive Strategies in Coral Reefs
  • Deciphering Communication Systems in Cetaceans
  • Conservation Challenges for Island Endemics
  • Complexities of Mating Systems in Arachnids

Botany Research Topics

  • Plant Defenses Against Herbivory: Chemical Warfare in the Plant Kingdom
  • Molecular Mechanisms of Drought Resistance in Succulents
  • Circadian Rhythms in Photosynthesis: A Closer Look
  • Biotechnological Approaches to Improve Crop Yield
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  • Investigating Disease Resistance in Commercially Important Crops
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  • Strategies for Invasive Plant Species Management
  • Understanding the Molecular Basis of Phototropism
  • Cyanobacteria and Nutrient Cycling in Aquatic Ecosystems
  • Unraveling the Genetic Basis of Plant Longevity
  • Biotic and Abiotic Stress Responses in Forest Trees
  • Applications of Plant Tissue Culture in Agriculture
  • Alpine Plant Adaptations: Surviving at High Altitudes

Developmental Biology Research Topics

  • Organogenesis: Tracing the Formation of Complex Structures in Mammals
  • Decoding the Mysteries of Axolotl Regeneration
  • Mechanisms of Early Embryonic Patterning in Drosophila
  • Epigenetic Regulation in Mammalian Neural Development
  • Investigating the Molecular Basis of Morphogenesis in Zebrafish
  • Neural Crest Cells: Pioneers in Vertebrate Development
  • Embryonic Development and Metamorphosis in Amphibians
  • Cell Fate Determination During Gastrulation
  • Signaling Pathways Involved in Limb Development
  • MicroRNAs in the Control of Cell Differentiation
  • Sex Determination Mechanisms in Reptiles
  • Axonal Guidance: Exploring Molecular Mechanisms
  • Intricate Choreography of Cell Movements in Gastrulation
  • Epigenetic Influence on Stem Cell Potency
  • Somitogenesis: Segmentation in Early Vertebrate Development
  • Imprinted Genes in Mammalian Development
  • Unraveling the Mechanisms of Asymmetric Cell Division
  • Molecular Regulation of Cardiac Development
  • Genetic Control of Eye Development in Drosophila
  • Exploring the Basis of Cellular Plasticity During Development

Environmental Biology Research Topics

  • Assessing Biodiversity in Freshwater Ecosystems: Challenges and Approaches
  • Climate Change and Species Distribution: Anticipating Shifts
  • Understanding the Persistence of Keystone Species in Urban Environments
  • Effects of Ocean Acidification on Marine Life
  • Soil Microbiome Composition and Its Influence on Plant Health
  • Plastic Pollution in Marine Ecosystems: Assessing the Scale
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  • Conservation Priorities in Biodiversity Hotspots
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  • Dynamics of Algal Blooms in Response to Nutrient Loading
  • Adaptation Strategies of Arctic Wildlife to Climate Change
  • Tracking the Movement of Pollutants in Aquatic Food Webs
  • Endocrine Disruptors in the Environment: Sources and Effects
  • Mangrove Ecosystems in the Face of Sea-Level Rise

Abortion Biology Research Topics

  • Deciphering Molecular Mechanisms Underlying Spontaneous Abortion
  • Influence of Maternal Stress Hormones on Early Pregnancy Outcomes
  • Understanding the Etiology of Recurrent Miscarriage
  • Immunological Aspects of Pregnancy and Abortion: An Interplay
  • Investigating Genetic Abnormalities in Cases of Spontaneous Abortion
  • Endocrine Disruptors and Pregnancy Outcomes: A Complex Relationship
  • Nutritional Factors Affecting Pregnancy Viability
  • Pathophysiology of Ectopic Pregnancy
  • Correlation Between Age and Miscarriage: Unraveling the Underlying Causes
  • Exploring the Intersection of Infections and Pregnancy Outcomes
  • Autoimmune Disorders and Their Influence on Pregnancy Termination
  • Epigenetic Modifications and Pregnancy Loss: An Uncharted Territory
  • Embryo Implantation Failure: Causes and Potential Interventions
  • Investigating the Role of Antiphospholipid Syndrome in Miscarriage
  • Assessing the Influence of Environmental Toxins on Pregnancy Outcomes
  • Cellular Mechanisms of Embryo Rejection
  • Physiological Responses to Termination of Pregnancy
  • Effects of Chronic Diseases on Pregnancy Outcomes
  • Understanding Fetal Development in High-Risk Pregnancies
  • Pathological Examination of Miscarriage: Advancements and Challenges

Recent Research Topics in Biotechnology

  • Precision Genome Editing: CRISPR and Beyond
  • Harnessing the Power of Microbial Factories for Biofuel Production
  • Exploring Cellular Agriculture: Lab-Grown Meat and Its Implications
  • Unraveling the Potential of Stem Cells in Regenerative Medicine
  • Advancements in Plant Genomics for Sustainable Agriculture
  • Nanotechnology in Drug Delivery Systems: Current Developments
  • Protein Engineering for Biotherapeutic Applications
  • Bioinformatics in Personalized Medicine: Opportunities and Challenges
  • Decoding the Microbiome: Health, Disease, and Biotechnological Applications
  • Synthetic Biology: Designing Biological Systems for Industrial Applications
  • Neuroengineering: Interfacing Electronics with the Brain
  • Biotechnology in Waste Management: Toward a Circular Economy
  • Gene Therapy Approaches to Rare Genetic Disorders
  • Biomaterials in Tissue Engineering: Opportunities and Challenges
  • Development of Biodegradable Plastics Through Microbial Fermentation
  • Biosensors for Environmental Monitoring: Emerging Techniques
  • Biotechnological Strategies for Antimicrobial Resistance
  • Microbial Biofilms in Industrial Processes: Pros and Cons
  • CRISPR as a Diagnostic Tool: Current Progress
  • Application of Biotechnology in Forensic Science: New Frontiers

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The Regulation and Function of Circular RNAs in Systems Biology Research

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About this Research Topic

Most eukaryotic genes are split by intron sequence which need to be removed by the splicing machinery from nascent pre-messenger RNAs (pre-mRNAs). The splicing process that joins the upstream 5’ splicing site (5’ ss) and downstream 3’ splicing sites (3’ ss) together is highly regulated, and can generate different transcripts from a single gene locus. High-throughput RNA sequencing has now revealed that splicing machinery can also join downstream 5’ ss to upstream 3’ ss in a process called ‘backsplicing’. Backsplicing generates circular RNAs (circRNAs) with covalently linked ends in a variety of organisms from fungi to humans. It is often facilitated by base-pairing between the flanking introns of circularized exon(s), RNA binding proteins, exon skipping events, and by the levels of core factors of splicing machinery, but the detailed mechanisms of the biogenesis of circRNA are still not fully understood. Although thousands of circRNAs have been identified by RNAseq in diverse organisms, the functional roles of most circRNAs remain largely unexplored and require further investigation. Circular RNAs (circRNAs) are abundantly expressed in various tissues and have been implicated in several diseases such as neurodegenerative diseases, cardiovascular disease and cancer. In recent years, systems biology research has focused more on developing novel methods and algorithms to identify and characterise circRNAs, as well as evaluating synthetic circRNAs as potential therapeutics. One of the most studied circRNAs is CDR1as/ciRS7 which is highly abundant in neurons and has more than 60 evolutionary conserved miR-7 binding sites. CDR1as was originally thought to sequester miR-7 by acting as a microRNA sponge to modulate the expression of target mRNAs of miR-7. Recent CDR1as KO mouse model data suggests that the main function of CDR1as is to stabilize miR-7 and/or control its localization in neurons at a systems level. In addition to functioning as microRNA sponge, circRNAs has been reported to have diverse functions including affecting transcription/splicing and even encoding functional proteins. The aim of this Research Topic is to collect Original Research Articles and Reviews which study and/or discuss the identification, regulation, and function of circRNAs using a system-wide approach. With this collection, we seek to improve our understanding of circRNA biogenesis and their functions in both normal physiological and disease conditions. Areas to be covered in this Research Topic may include, but not limited to: • Novel computational methods for circRNA identification • circRNA networks • Novel methods for circRNA enrichment and profiling. • Regulation of circRNA in physiological and disease conditions. • Function of circRNA e.g. sponging microRNA, translation etc. • Degradation of circRNA in steady state or stress condition. • Applications of artificial circRNAs in disease therapy • Applications of circRNAs for therapeutic discovery • CircRNA as biomarkers for disease.

Keywords : circular RNA, circRNA, systems biology, splicing

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  • April 6, 2024 | “Unheard of in Structural Biology” – New Research Unveils Enzymatic Keys to Immune System Regulation
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“Unheard of in Structural Biology” – New Research Unveils Enzymatic Keys to Immune System Regulation

By Scripps Research Institute April 6, 2024

Illustration of Human Immune System

A recent Scripps Research study has identified the detailed structures of PLD3 and PLD4, enzymes critical for nucleic acid degradation and immune regulation. The discovery, enabling the understanding of diseases like lupus, rheumatoid arthritis, and Alzheimer’s, reveals novel enzymatic functions and provides a foundation for future therapeutic approaches targeting these enzymes.

Scientists at Scripps Research have developed atomic-level structural models of enzymes linked to autoimmune and inflammatory conditions, such as lupus and Alzheimer’s disease.

When nucleic acids, such as DNA or RNA , accumulate in a cell’s cytoplasm, they trigger an alert to the immune system. Under normal circumstances, enzymes are tasked with clearing out these nucleic acids to prevent problems. However, if these enzymes fail to function properly and the immune system intervenes, it may result in autoimmune and inflammatory diseases.

In a new study recently published in the journal Structure , Scripps Research scientists present the previously undescribed structure of two of these nucleic acid -degrading enzymes—PLD3 and PLD4. Understanding these enzymes’ structures and molecular details is an important step toward designing therapies for the various diseases that arise when they malfunction, which include lupus erythematosus, rheumatoid arthritis, and Alzheimer’s disease.

“These enzymes are important for cleaning up the cellular environment, and they also set the threshold for what is considered an infection or not,” says senior author David Nemazee, PhD, professor in the Department of Immunology and Microbiology at Scripps Research. “I’m hoping someday we may be able to help patients based on this information.”

Enzyme Functionality and Analysis Techniques

Enzymes are proteins that speed up chemical reactions by binding and reacting to specific molecules called substrates. In the case of PLD3 and PLD4, the substrate is a strand of RNA or DNA, which the enzymes break down nucleotide by nucleotide.

The team used X-ray crystallography to build atomic-scale models of the PLD3 and PLD4 in multiple states or situations, allowing them to examine how their shapes changed over the course of the catalytic reaction. This included when the enzymes were resting, or when they were actively bound to a substrate.

“These models allow us to visualize PLD3 and PLD4 very clearly and with high resolution, so we know exactly how every atom interacts, meaning we can deduce how the enzymes work,” says first author Meng Yuan, a staff scientist in the Department of Integrative Structural and Computational Biology at Scripps Research.

Structural Models of PLD3 and PLD4

Structural models of PLD3 and PLD4, enzymes that degrade nucleic acids in the cytoplasm. The enzymes’ active (or binding) sites are indicated with black arrows. Credit: Scripps Research

The structural analyses revealed that PLD3 and PLD4 are structurally similar and that they degrade DNA and RNA in a very similar fashion, even though PLD4 is a larger protein. Both enzymes degrade nucleic acids via a two-step process.

“We call this process a two-step catalysis: bite down and release,” says Yuan. “In the first step, the enzyme bites down on the DNA strand and separates a single ‘brick’ or nucleotide from the rest of the strand, and in the second step, it opens its ‘mouth’ and releases the brick to be recycled.”

Because the enzymatic reaction happens so quickly—within milliseconds—researchers needed to use an alternative substrate to visualize the enzymes’ structure during catalysis. To do this, they incubated the enzymes together with a molecule that looks very similar to the DNA that the enzyme usually degrades, but that the enzymes degrade much more slowly.

Discovering New Enzymatic Functions

This method uncovered a previously unknown function for one of the enzymes: In addition to biting off nucleotides from single-stranded RNA and DNA, PLD4 also showed phosphatase activity, which means it might also be involved in breaking down DNA’s phosphate backbone.

“I think it’s amazing that the crystal structure told us about this phosphatase activity,” says Nemazee. “To discover new enzymatic activity is unheard of in structural biology. It’s only because Meng was able to solve such an amazingly accurate and detailed structure that he could inform us about this extra enzymatic activity that we had no idea about.”

After they had elucidated PLD3 and PLD4’s usual structure, the researchers examined the structure of variants that are associated with diseases, including Alzheimer’s and spinocerebellar ataxia. These analyses revealed that some of these variants had decreased enzymatic capability, while others—including a mutation associated with late-onset Alzheimer’s—appeared to be more active.

“Some of our data suggests that one of these Alzheimer’s-associated enzyme variants might function better, which was a surprise to me, but it also may be less stable and more easily aggregated,” says Nemazee.

The researchers plan to continue investigating the structure and function of these enzymes. Their next steps include exploring possible ways of inhibiting the enzymes in scenarios where they are overactive, and they also plan to investigate the possibility of replacing the enzymes in people who carry non-functional (or non-working) versions.

Reference: “Structural and mechanistic insights into disease-associated endolysosomal exonucleases PLD3 and PLD4” by Meng Yuan, Linghang Peng, Deli Huang, Amanda Gavin, Fangkun Luan, Jenny Tran, Ziqi Feng, Xueyong Zhu, Jeanne Matteson, Ian A. Wilson and David Nemazee, 26 March 2024, Structure . DOI: 10.1016/j.str.2024.02.019

This study was supported by the National Institutes of Health (grants R01AI142945 and RF1AG070775) and Skaggs Institute for Chemical Biology at Scripps Research.

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2022-2023 biological sciences scholarship and prize winners

The Department of Biological Sciences congratulates our Wayne State Warriors on their recent achievements!

Undergraduate awards

Nicolette therese keller endowed scholarship in biological sciences.

Hajir Laft, Essra Aljaberry, Ammar Alromdhan

Kathryn and Gary Armstrong Endowed Scholarship

Julia Llana, Rita Haddad

Graduate awards

Brenna Friday and Katrina Lewandowski from the lab of Donna Kashian received prestigious Knauss Fellowships in Washington DC . As a result, Brenna Friday will work in the Environmental Protection Agency’s Office of Water’s Office of Science and Technology as a biocriteria, nutrients and harmful algal blooms fellow. Katrina Lewandowski will become a coastal resilience specialist for the National Oceanic and Atmospheric Administration.

Brenna Friday

Hashan Sri Madhubhashana Jayarathn

Hashan Sri Madhubhashana Jayarathne from the lab of Dr. Sadagurski received of the best poster award at the 2023 American Aging Association (AGE) Annual Meeting.

Hashan Sri Madhubhashana Jayarathne

Graduate student teaching awards

Sarah black.

Sarah was nominated by research faculty and students for her teaching in BIO 5740/7740: General Entomology. A student noted “Sarah went out of her way to provide additional time outside of class in order to ensure students had enough time and one on one help to properly pin and identify the insects that they collected. I believe her teaching of this course was a big source of inspiration for the students to continue practicing the material they had learned once the class was over.”

Savannah Kozole (Karen Beningo lab)

Savannah was nominated for her teaching in BIO 4630: Histology. One student commented: “Her explanations in class to introduce the topic were clear and concise, she would relate new material in the course such as certain organs of a system to earlier topics to ensure we had a basis for new material as well continuously keeping earlier material relevant. I found this aspect of her teaching to be supportive of actively learning and understanding new material, instead of isolating each section then just memorizing. Furthermore, I appreciated her encouragement of students’ participation.”

Eleazar Reward (Haidong Gu lab)

Eleazar was nominated for his teaching in BIO 3070: Genetics. One student stated: “I can confidently say that he is an exceptional teaching assistant. His commitment to creating a dynamic and inclusive learning environment made a significant impact on my learning experience. Eleazar’s passion for genetics was evident in every class session, and he effortlessly conveyed complex concepts in a way that was engaging and accessible to all students.”

Kailynn Sparks (Mark VanBerkum lab)

Kailynn was recognized for her teaching in BIO 2600: Cell Biology and BIO 4120: Comparative Physiology. One student commented: “She guided us as a class through each stage of the semester with simultaneous thoroughness and expedience. Both aspects of her teaching were really appreciated as I wanted to make sure I learned a complete picture of the lesson but also wanted to get it done and get home to enjoy the weather. She wasted no time. For each lab, she would begin by giving us an overview on the whiteboard and answering any procedural questions the class might have. We would then grab our supplies and begin, and she would go by each group and watch us and provide guidance when asked. She was available, friendly, and at times even funny. There really isn’t anymore one could ask of a TA.”

Sumit Bandyopadhyay

Graduate student Sumit Bandyopadhyay receives ATTRACT funding from WSU Chemical Biology Interface.

Science Coalition’s #FundItForward video challenge

Graduate students Mohamed Chakkour and Chisom Onu win first place in The Science Coalition’s #FundItForward video challenge .

Graduate student research awards

Kendall case (miriam greenberg lab).

Among other accomplishments, Kendall published a first-author review and a first-author research paper in revision in the highly regarded journal Scientific Reports. Miriam Greenberg remarked that Kendall chose the most intractable project available in the lab, and introduced numerous technologies to the lab to complete the mission, only to find out that the hypothesized model was incorrect. However, Kendall was committed to communicating his findings so that others in the field will not spend time and resources to unnecessarily repeating this work.

Imad Soukar (Lori Pile lab)

Imad impressed the award committee by a co-first author review, a paper under revision in Biology Open, a co-authorship on a published paper in Biochimica et Biophysica Acta and a co-authorship on a paper under revision. Corroborating a strong trajectory, Imad defended his Ph.D. thesis research on July 31.

Linh Vo (Miriam Greenberg lab)

Linh stood out by the publication of a first-author paper in the "Journal of Biological Chemistry," a second authorship in Biochimica et Biophysica Acta, and delivering an invited talk at an international meeting. In addition, Linh completed her Ph.D. training in under five years, which is an extremely impressive accomplishment all by itself.

Armstrong-Bromel Inspirational Graduate Student Teaching and Mentoring Awardee

Maggie sneideman.

While working on dosage compensation in the fruit fly X-chromosome for her Ph.D. thesis research, Maggie taught BIO 3070: Genetics as graduate teaching assistant, where many students became fans of her. One of them stated that “If she were a professor, I would be sure to take every class of hers.” To us, that sounds like a call to higher duty. Of note, this year the department received over 100 nominations for this award, almost all from undergraduates.

Thomas Rumble Fellowship Awardees

  • Hashan Jayarathne
  • Brenna Friday

Research retreat awards

2023 best poster winners.

Ali Rashid, Mohamed Dabaja and Vikalp Kumar. Second row, from left to right, Sydney Scofield, Brendyn St. Louis, Aishwarya Ghosh, Emma Fidler, Lin Rayes and Hadi Yassine holding certificates

Graduate students

  • Mohamed Dabaja (Joy Alcedo lab)
  • Aishwarya Ghosh (Jared Schrader lab)
  • Emma Fidler (Athar Ansari lab)
  • Vikalp Kumar (Miriam Greenberg lab)
  • Sydney Scofield (Marianna Sadagurski lab)
  • Brendyn St. Louis (PC Lee lab)
  • Aishwarya Ghosh & Hadi Yassine (Jared Schrader lab)

Undergraduate students

  • Ali Rashid and Lin Rayes (Njus lab)

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Collection  10 March 2022

Top 100 in Cell and Molecular Biology

This collection highlights our most downloaded* cell and molecular biology papers published in 2021. Featuring authors from around the world, these papers showcase valuable research from an international community.

*Data obtained from SN Inights, which is based on Digital Science's Dimensions.

image of closeup of red cells

Antibacterial apple cider vinegar eradicates methicillin resistant Staphylococcus aureus and resistant Escherichia coli

  • Darshna Yagnik
  • Malcolm Ward
  • Ajit J. Shah

research topic in biology

Inhibiting SARS-CoV-2 infection in vitro by suppressing its receptor, angiotensin-converting enzyme 2, via aryl-hydrocarbon receptor signal

  • Keiji Tanimoto
  • Kiichi Hirota
  • Takemasa Sakaguchi

research topic in biology

Targeted clearance of senescent cells using an antibody-drug conjugate against a specific membrane marker

  • Marta Poblocka
  • Akang Leonard Bassey
  • Salvador Macip

research topic in biology

Catechin and curcumin interact with S protein of SARS-CoV2 and ACE2 of human cell membrane: insights from computational studies

  • Atala B. Jena
  • Namrata Kanungo
  • Jagneshwar Dandapat

research topic in biology

Structure based pharmacophore modeling, virtual screening, molecular docking and ADMET approaches for identification of natural anti-cancer agents targeting XIAP protein

  • Firoz A. Dain Md Opo
  • Mohammed M. Rahman
  • Abdullah M. Asiri

research topic in biology

Low-dose Drosera rotundifolia induces gene expression changes in 16HBE human bronchial epithelial cells

  • Fabio Arruda-Silva
  • Paolo Bellavite
  • Marta Marzotto

research topic in biology

Classification and prediction of protein–protein interaction interface using machine learning algorithm

  • Subhrangshu Das
  • Saikat Chakrabarti

research topic in biology

Carvacrol exhibits rapid bactericidal activity against Streptococcus pyogenes through cell membrane damage

  • Niluni M. Wijesundara
  • Song F. Lee
  • H. P. Vasantha Rupasinghe

research topic in biology

SHP2 blockade enhances anti-tumor immunity via tumor cell intrinsic and extrinsic mechanisms

  • Morvarid Mohseni
  • Silvia Goldoni

research topic in biology

Polyunsaturated ω-3 fatty acids inhibit ACE2-controlled SARS-CoV-2 binding and cellular entry

  • Aleksandra Niedzwiecki
  • Matthias Rath

research topic in biology

Arrayed CRISPR reveals genetic regulators of tau aggregation, autophagy and mitochondria in Alzheimer’s disease model

  • Robert V. Talanian

research topic in biology

Novel myostatin-specific antibody enhances muscle strength in muscle disease models

  • Hiroyasu Muramatsu
  • Taichi Kuramochi
  • Junichi Nezu

research topic in biology

Serine 477 plays a crucial role in the interaction of the SARS-CoV-2 spike protein with the human receptor ACE2

  • Georg Steinkellner
  • Christian C. Gruber

research topic in biology

Improved methods for RNAseq-based alternative splicing analysis

  • Rebecca F. Halperin
  • Apurva Hegde
  • Nicholas J. Schork

research topic in biology

SIRT1 promotes lipid metabolism and mitochondrial biogenesis in adipocytes and coordinates adipogenesis by targeting key enzymatic pathways

  • Yasser Majeed
  • Najeeb Halabi
  • Nayef A. Mazloum

research topic in biology

A directional 3D neurite outgrowth model for studying motor axon biology and disease

  • Xandor M. Spijkers
  • Svetlana Pasteuning-Vuhman
  • R. Jeroen Pasterkamp

research topic in biology

Structural insights into SARS-CoV-2 spike protein and its natural mutants found in Mexican population

  • Yudibeth Sixto-López
  • José Correa-Basurto
  • Sarita Montaño

research topic in biology

Lipid bilayer degradation induced by SARS-CoV-2 spike protein as revealed by neutron reflectometry

  • Alessandra Luchini
  • Samantha Micciulla
  • Giovanna Fragneto

research topic in biology

Scale-up fermentation of Escherichia coli for the production of recombinant endoglucanase from Clostridium thermocellum

  • Iram Shahzadi
  • Maryam A. Al-Ghamdi
  • Imran Kazmi

research topic in biology

Drug design and repurposing with DockThor-VS web server focusing on SARS-CoV-2 therapeutic targets and their non-synonym variants

  • Isabella A. Guedes
  • Leon S. C. Costa
  • Laurent E. Dardenne

research topic in biology

Ultraviolet radiation protection potentials of Methylene Blue for human skin and coral reef health

  • Zheng-Mei Xiong
  • Xiaojing Mao

research topic in biology

ABBV-744 as a potential inhibitor of SARS-CoV-2 main protease enzyme against COVID-19

  • Zeynab Fakhar
  • Aijaz Ahmad

research topic in biology

Green synthesis of selenium nanoparticles mediated from Ceropegia bulbosa Roxb extract and its cytotoxicity, antimicrobial, mosquitocidal and photocatalytic activities

  • Vetrivel Cittrarasu
  • Durairaj Kaliannan
  • Maruthupandian Arumugam

research topic in biology

Random forest classification for predicting lifespan-extending chemical compounds

  • Sofia Kapsiani
  • Brendan J. Howlin

research topic in biology

Development, characterization, and applications of multi-material stereolithography bioprinting

  • Bagrat Grigoryan
  • Daniel W. Sazer
  • Jordan S. Miller

research topic in biology

Biosynthesis and characterization of gold nanoparticles using Brazilian red propolis and evaluation of its antimicrobial and anticancer activities

  • C. E. A. Botteon
  • L. B. Silva
  • P. D. Marcato

research topic in biology

Reporter gene comparison demonstrates interference of complex body fluids with secreted luciferase activity

  • B. A. C. Housmans
  • P. M. van der Kraan

research topic in biology

High-resolution transcriptional landscape of xeno-free human induced pluripotent stem cell-derived cerebellar organoids

  • Samuel Nayler
  • Devika Agarwal
  • Esther B. E. Becker

research topic in biology

Proteome-wide profiling and mapping of post translational modifications in human hearts

  • Navratan Bagwan
  • Henrik H. El Ali
  • Alicia Lundby

research topic in biology

Three-dimensional ultrastructure of giant mitochondria in human non-alcoholic fatty liver disease

  • Gerald J. Shami
  • Delfine Cheng
  • Filip Braet

research topic in biology

Zbp1-positive cells are osteogenic progenitors in periodontal ligament

  • Tsugumi Ueda
  • Tomoaki Iwayama
  • Shinya Murakami

research topic in biology

Neurotropic influenza A virus infection causes prion protein misfolding into infectious prions in neuroblastoma cells

  • Hideyuki Hara
  • Junji Chida
  • Suehiro Sakaguchi

research topic in biology

Self-organization and culture of Mesenchymal Stem Cell spheroids in acoustic levitation

  • Nathan Jeger-Madiot
  • Lousineh Arakelian
  • Jean-Luc Aider

research topic in biology

Blockade of SARS-CoV-2 spike protein-mediated cell–cell fusion using COVID-19 convalescent plasma

research topic in biology

Systematic evaluation of multiple qPCR platforms, NanoString and miRNA-Seq for microRNA biomarker discovery in human biofluids

  • Lewis Z. Hong
  • Shian-Jiun Shih

research topic in biology

Ionizing radiation exposure of stem cell-derived chondrocytes affects their gene and microRNA expression profiles and cytokine production

  • Ewelina Stelcer
  • Katarzyna Kulcenty
  • Wiktoria Maria Suchorska

research topic in biology

Improved functional properties of meat analogs by laccase catalyzed protein and pectin crosslinks

  • Kiyota Sakai
  • Yukihide Sato
  • Shotaro Yamaguchi

research topic in biology

Delivery of functional exogenous proteins by plant-derived vesicles to human cells in vitro

  • Luiza Garaeva
  • Roman Kamyshinsky
  • Tatiana Shtam

research topic in biology

Identification of germ cell-specific Mga variant mRNA that promotes meiosis via impediment of a non-canonical PRC1

  • Yuka Kitamura
  • Kousuke Uranishi
  • Akihiko Okuda

research topic in biology

Modified recombinant human erythropoietin with potentially reduced immunogenicity

  • Thanutsorn Susantad
  • Mayuree Fuangthong
  • Ram Sasisekharan

research topic in biology

Discovery of a new class of integrin antibodies for fibrosis

  • Masahisa Handa

research topic in biology

DSS-induced colitis is associated with adipose tissue dysfunction and disrupted hepatic lipid metabolism leading to hepatosteatosis and dyslipidemia in mice

  • Jeonghyeon Kwon
  • Chungho Lee
  • Chang-Kee Hyun

research topic in biology

Activation of NF-κB and induction of proinflammatory cytokine expressions mediated by ORF7a protein of SARS-CoV-2

  • Chia-Ming Su
  • Dongwan Yoo

research topic in biology

Development of a target identification approach using native mass spectrometry

  • Miaomiao Liu
  • Wesley C. Van Voorhis
  • Ronald J. Quinn

research topic in biology

Optimized design parameters for CRISPR Cas9 and Cas12a homology-directed repair

  • Mollie S. Schubert
  • Bernice Thommandru
  • Garrett R. Rettig

research topic in biology

Single-cell differential splicing analysis reveals high heterogeneity of liver tumor-infiltrating T cells

  • Biaofeng Zhou
  • Shiping Liu

research topic in biology

Generation of proliferating human adult hepatocytes using optimized 3D culture conditions

  • Sophie Rose
  • Frédéric Ezan
  • Georges Baffet

research topic in biology

Evaluation of microalgae polysaccharides as biostimulants of tomato plant defense using metabolomics and biochemical approaches

  • Farid Rachidi
  • Redouane Benhima
  • Hicham El Arroussi

research topic in biology

Detection and quantification of γ-H2AX using a dissociation enhanced lanthanide fluorescence immunoassay

  • Felicite K. Noubissi
  • Amber A. McBride
  • Sandra M. Davern

research topic in biology

Unraveling the stability landscape of mutations in the SARS-CoV-2 receptor-binding domain

  • Mohamed Raef Smaoui
  • Hamdi Yahyaoui

research topic in biology

A comprehensive analysis of novel disulfide bond introduction site into the constant domain of human Fab

  • Hitomi Nakamura
  • Moeka Yoshikawa
  • Takatoshi Ohkuri

research topic in biology

Homology between SARS CoV-2 and human proteins

  • Vladimir Khavinson
  • Alexander Terekhov
  • Alexander Maryanovich

research topic in biology

A genome-wide CRISPR/Cas9 screen to identify phagocytosis modulators in monocytic THP-1 cells

  • Benjamin Lindner
  • Michael Schuler

research topic in biology

PTEN loss promotes oncogenic function of STMN1 via PI3K/AKT pathway in lung cancer

  • Guangsu Xun

research topic in biology

Development of a yeast cell surface display method using the SpyTag/SpyCatcher system

  • Kaho Kajiwara
  • Wataru Aoki
  • Mitsuyoshi Ueda

research topic in biology

The dimer-monomer equilibrium of SARS-CoV-2 main protease is affected by small molecule inhibitors

  • Lucia Silvestrini
  • Norhan Belhaj
  • Francesco Spinozzi

research topic in biology

In-depth transcriptomic analysis of human retina reveals molecular mechanisms underlying diabetic retinopathy

  • Kolja Becker
  • Holger Klein
  • Remko A. Bakker

research topic in biology

Identification of extracellular matrix proteins secreted by human dermal fibroblasts cultured in 3D electrospun scaffolds

  • Atena Malakpour-Permlid
  • Irina Buzzi
  • Stina Oredsson

research topic in biology

Novel methods to establish whole-body primary cell cultures for the cnidarians Nematostella vectensis and Pocillopora damicornis

  • James D. Nowotny
  • Michael T. Connelly
  • Nikki Traylor-Knowles

research topic in biology

Culture and differentiation of rabbit intestinal organoids and organoid-derived cell monolayers

  • Michael Frese
  • Robyn N. Hall

research topic in biology

Cannabidiol induces autophagy via ERK1/2 activation in neural cells

  • Talita A. M. Vrechi
  • Anderson H. F. F. Leão
  • Gustavo J. S. Pereira

research topic in biology

Seaweed cellulose scaffolds derived from green macroalgae for tissue engineering

  • Nurit Bar-Shai
  • Orna Sharabani-Yosef
  • Alexander Golberg

research topic in biology

Outer membrane vesicles containing OmpA induce mitochondrial fragmentation to promote pathogenesis of Acinetobacter baumannii

  • Varnesh Tiku
  • Eric M. Kofoed
  • Man-Wah Tan

research topic in biology

A scaffold-free approach to cartilage tissue generation using human embryonic stem cells

  • Lauren A. Griffith
  • Katherine M. Arnold
  • Franchesca D. Houghton

research topic in biology

The Penn State Protein Ladder system for inexpensive protein molecular weight markers

  • Ryan T. Santilli
  • John E. Williamson III

research topic in biology

Inhibition of succinate dehydrogenase activity impairs human T cell activation and function

  • Claudia Nastasi
  • Andreas Willerlev-Olsen
  • Anders Woetmann

research topic in biology

Glucose confers protection to Escherichia coli against contact killing by Vibrio cholerae

  • Cristian V. Crisan
  • Holly L. Nichols
  • Brian K. Hammer

research topic in biology

Novel standardized method for extracellular flux analysis of oxidative and glycolytic metabolism in peripheral blood mononuclear cells

  • Joëlle J. E. Janssen
  • Bart Lagerwaard
  • Vincent C. J. de Boer

research topic in biology

3D bioprinting of hepatocytes: core–shell structured co-cultures with fibroblasts for enhanced functionality

  • Rania Taymour
  • David Kilian

research topic in biology

Role of miRNAs shuttled by mesenchymal stem cell-derived small extracellular vesicles in modulating neuroinflammation

  • Debora Giunti
  • Chiara Marini
  • Antonio Uccelli

research topic in biology

Isolation of viable Babesia bovis merozoites to study parasite invasion

  • Hassan Hakimi
  • Masahito Asada
  • Shinichiro Kawazu

research topic in biology

Nutritional, phytochemical, and in vitro anticancer potential of sugar apple ( Annona squamosa ) fruits

  • Mohamed Gamal Shehata
  • Marwa Muhammad Abu-Serie
  • Sobhy Ahmed El-Sohaimy

research topic in biology

AptaNet as a deep learning approach for aptamer–protein interaction prediction

  • Reza Ferdousi

research topic in biology

Comprehensive virtual screening of 4.8 k flavonoids reveals novel insights into allosteric inhibition of SARS-CoV-2 M PRO

  • Gabriel Jiménez-Avalos
  • A. Paula Vargas-Ruiz
  • COVID-19 Working Group in Perú

research topic in biology

Comparison of the sensitivity of Western blotting between PVDF and NC membranes

  • Yufang Xiang
  • Yuanyuan Zheng
  • Weijie Dong

research topic in biology

Elovanoids downregulate SARS-CoV-2 cell-entry, canonical mediators and enhance protective signaling in human alveolar cells

  • Jorgelina M. Calandria
  • Surjyadipta Bhattacharjee
  • Nicolas G. Bazan

research topic in biology

The post-translational modification landscape of commercial beers

  • Edward D. Kerr
  • Christopher H. Caboche
  • Benjamin L. Schulz

research topic in biology

Anticancer potential of rhizome extract and a labdane diterpenoid from Curcuma mutabilis plant endemic to Western Ghats of India

  • T. Lakshmipriya
  • P. R. Manish Kumar

research topic in biology

Chemotaxis and swarming in differentiated HL-60 neutrophil-like cells

  • Kehinde Adebayo Babatunde
  • Daniel Irimia

research topic in biology

Integrated, automated maintenance, expansion and differentiation of 2D and 3D patient-derived cellular models for high throughput drug screening

  • Ibrahim Boussaad
  • Gérald Cruciani
  • Rejko Krüger

research topic in biology

In vitro synthesis of 32 translation-factor proteins from a single template reveals impaired ribosomal processivity

  • David Foschepoth
  • Christophe Danelon

research topic in biology

Comparative transcriptome analysis reveals resistant and susceptible genes in tobacco cultivars in response to infection by Phytophthora nicotianae

  • Mingming Sun
  • Yuanying Wang

research topic in biology

Protocol for preparation of heterogeneous biological samples for 3D electron microscopy: a case study for insects

  • Alexey A. Polilov
  • Anastasia A. Makarova
  • Harald Hess

research topic in biology

Downregulation of E-cadherin in pluripotent stem cells triggers partial EMT

  • A. Lombardi

research topic in biology

Identification of the first highly selective inhibitor of human lactate dehydrogenase B

  • Sachio Shibata
  • Satoshi Sogabe
  • Tomoyoshi Soga

research topic in biology

Estrogen-related receptor alpha (ERRα) is a key regulator of intestinal homeostasis and protects against colitis

  • Charlotte Scholtes

research topic in biology

Precision modification of the human gut microbiota targeting surface-associated proteins

  • Raquel Marcos-Fernández
  • Lorena Ruiz
  • Borja Sánchez

research topic in biology

Test conditions can significantly affect the results of in vitro cytotoxicity testing of degradable metallic biomaterials

  • Eva Jablonská
  • Jiří Kubásek

research topic in biology

A systems pharmacology approach to identify the autophagy-inducing effects of Traditional Persian medicinal plants

  • Pouria Mosaddeghi
  • Mahboobeh Eslami
  • Younes Ghasemi

research topic in biology

Molecular dynamics and in silico mutagenesis on the reversible inhibitor-bound SARS-CoV-2 main protease complexes reveal the role of lateral pocket in enhancing the ligand affinity

  • Ying Li Weng
  • Shiv Rakesh Naik
  • Aravindhan Ganesan

research topic in biology

Cysteine: an overlooked energy and carbon source

  • Luise Göbbels
  • Anja Poehlein
  • Marie Charlotte Schoelmerich

research topic in biology

Generation of somatic mitochondrial DNA-replaced cells for mitochondrial dysfunction treatment

  • Hideki Maeda
  • Daisuke Kami
  • Satoshi Gojo

research topic in biology

In silico investigation of critical binding pattern in SARS-CoV-2 spike protein with angiotensin-converting enzyme 2

  • Farzaneh Jafary
  • Sepideh Jafari
  • Mohamad Reza Ganjalikhany

research topic in biology

Flexibility and mobility of SARS-CoV-2-related protein structures

  • Rudolf A. Römer
  • Navodya S. Römer
  • A. Katrine Wallis

research topic in biology

The effect of acute moderate-intensity exercise on the serum and fecal metabolomes and the gut microbiota of cross-country endurance athletes

  • Mariangela Tabone
  • Carlo Bressa
  • Mar Larrosa

research topic in biology

Bloom syndrome DNA helicase deficiency is associated with oxidative stress and mitochondrial network changes

  • Veena Subramanian
  • Brian Rodemoyer
  • Kristina H. Schmidt

research topic in biology

Robust and accurate prediction of protein–protein interactions by exploiting evolutionary information

  • Yan-Bin Wang

research topic in biology

Iron supplementation regulates the progression of high fat diet induced obesity and hepatic steatosis via mitochondrial signaling pathways

  • Naho Kitamura
  • Yoko Yokoyama
  • Mitsuhiro Watanabe

research topic in biology

Kokumi taste perception is functional in a model carnivore, the domestic cat ( Felis catus )

  • A. Laffitte
  • S. J. McGrane

research topic in biology

Decoding empagliflozin’s molecular mechanism of action in heart failure with preserved ejection fraction using artificial intelligence

  • Antoni Bayes-Genis
  • Oriol Iborra-Egea
  • Josep Lupón

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