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How do I include Highlights with my manuscript?

Highlights are a short collection of three to five bullet points that:

  • Provide readers with a quick textual overview of the article.
  • Convey the core findings.
  • Describe the essence of the research (i.e. results or conclusion).
  • Highlight what's distinctive about it.

Highlights will be displayed in online search result lists, the contents list and in the online article, but won't (yet) appear in the article PDF file or print.

Answer Highlights are mandatory for some journals and optional for others. You can check the requirements for the journal you're submitting to by reading the Guide for Authors. To find the Guide for Authors:

  • Navigate to the journal's Homepage. To find the journal's Homepage search for the journal using the search box under 'Find by journal title' on the journal author's page .
  • Click on 'Guide for Authors' in the left-hand menu.

Highlights should be submitted in the following way:

Unless otherwise instructed in the Guide for Authors, Highlights should be included as a separate source file (i.e. Microsoft Word not PDF).

  • Select 'Highlights' from the drop-down file list when uploading files.
  • Use 'Highlights' as the file name.

With these specifications:

  • Include 3 to 5 highlights.
  • Each individual Highlight should be a maximum of 85 characters long, including spaces.
  • Only the core results of the paper should be covered.

Biochimica et Biophysica Acta (BBA), Bioenergetics, Volume 1807, Issue 10, October 2011, 1364-1369  

  • A conformational two-state mechanism for proton pumping complex I is proposed.
  • The mechanism relies on stabilization changes of anionic ubiquinone intermediates.
  • Electron-transfer and protonation should be strictly controlled during turnover.

Learning and Instruction, Volume 21, Issue 6, December 2011, 746-756  

  • Fading of a script alone does not foster domain-general strategy knowledge.
  • Performance of the strategy declines during the fading of a script.
  • Monitoring by a peer keeps performance of the strategy up during script fading.
  • Performance of a strategy after fading fosters domain-general strategy knowledge.
  • Fading and monitoring by a peer combined foster domain-general strategy knowledge.  

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How to Write Highlights for a Paper

Last Updated: March 20, 2024 Fact Checked

This article was reviewed by Gerald Posner and by wikiHow staff writer, Jennifer Mueller, JD . Gerald Posner is an Author & Journalist based in Miami, Florida. With over 35 years of experience, he specializes in investigative journalism, nonfiction books, and editorials. He holds a law degree from UC College of the Law, San Francisco, and a BA in Political Science from the University of California-Berkeley. He’s the author of thirteen books, including several New York Times bestsellers, the winner of the Florida Book Award for General Nonfiction, and has been a finalist for the Pulitzer Prize in History. He was also shortlisted for the Best Business Book of 2020 by the Society for Advancing Business Editing and Writing. This article has been fact-checked, ensuring the accuracy of any cited facts and confirming the authority of its sources. This article has been viewed 48,983 times.

The highlights for a scientific paper make it easier for people to find it using a search engine. Ideally, your highlights serve as a sort of "elevator pitch" for your paper, describing the results and any new methods you used. Although it depends on the publisher, the highlights for a paper will usually be no more than 3 or 4 bullet-point phrases. You typically don't need to worry about your highlights until the final editing stages before your paper is published. However, strong highlights can get your paper noticed online more quickly, which can give your research a tremendous advantage. [1] X Research source

Drafting the Highlights for Your Paper

An essay open on a laptop with the main elements highlighted.

  • Conversely, good highlights also keep a potential reader from wasting their time. If your paper doesn't cover information that they need to know or are interested in, highlights let them know immediately so they don't have to read through half your paper before they find that out.

Step 2 Use active voice to keep your writing concise.

  • For example, you would write "UV rays affect skin's overall health" rather than "skin's overall health is affected by sun exposure."
  • Research papers often use passive voice, which is more wordy and difficult to understand. Because highlights have a strict length requirement, using active voice allows you to stay within the character limits while including the most important information from your article. For example, you might write: "Prolonged exposure to light damages skin cells."

Step 3 Revise for a general audience rather than your peers.

  • Use the simplest words possible, even if they aren't technically accurate. For example, instead of referring to "squamous cells," you could say "skin cells" or simply "skin." Your paper will get into the specific cells studied.

Tip: If you know a child or teenager, read your highlights to them and ask if they can understand what your paper is about. If they don't, ask them what they didn't understand and keep revising.

Step 4 Proofread highlights carefully.

  • One method of proofreading is to read your highlights backward, moving word by word. This encourages you to focus on each individual word rather than the phrase as a whole.
  • It's also a good idea to let someone else give your highlights a read-through. Someone completely unfamiliar with your highlights or your paper might notice errors you've repeatedly overlooked because you know what you meant to say.

Using Proper Formatting for Your Highlights

Step 1 Ask the publisher what type of document to use for your highlights.

  • For example, the National Science Foundation wants each highlight on an individual Microsoft PowerPoint slide.
  • Highlights were introduced by the publisher Elsevier and many journals and publishers use similar procedures. If the journal or publisher tells you to use Elsevier's requirements, you can get those at https://www.elsevier.com/authors/journal-authors/highlights .

Step 2 Check the length requirements.

  • If you're providing your highlights in bullet points, the bullet point itself typically isn't considered a character. However, all other spaces and punctuation are.
  • Some journals or publishers may also have a minimum length. Even if a specific minimum length isn't given, having a highlight that's only 2 or 3 words typically doesn't provide enough information to a potential reader to be helpful.

Tip: You can typically adjust the settings of your word processing program to count characters rather than words. This will make it easier, as you're revising, to ensure your highlights stay within the length requirements.

Step 3 Complete any required forms to grant permission to use highlights.

  • Double-check to make sure you've met all the publisher's requirements before you submit your highlights. Violations of the publisher's protocol could delay the publication of your paper.

Expert Q&A

You might also like.

Write a News Article

  • ↑ https://www.elsevier.com/authors/journal-authors/highlights
  • ↑ https://author.miguelpanao.com/writing-meaningful-highlights-in-scientific-papers/
  • ↑ https://www.nsf.gov/mps/che/nuggets/highlight-writing.pdf

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Writing meaningful Highlights in scientific papers

One novelty in scientific papers in the last decade was Elsevier’s introduction of highlights. Are authors paying sufficient attention to highlights writing?

research highlights example

Highlights are 3 to 5 short sentences containing core findings of the research described in the paper. Highlights are available only online with the purpose of driving a person’s attention toward reading the paper. Therefore, when we’re invited to review a paper, the core findings are one of the first things we need to review and … what a mess!

Instead of core findings we read a short version of the title, operating conditions, etc. It’s like we’re reading an abstract divided into short sentences. So I wondered, is it possible to find guidelines to write more meaningful highlights by ourselves, instead of paying someone else to do it for us?

I find highlights a very important step in scientific articles. Thus, these are my 6 “Highlights” for writing more meaningful highlights based on experience, Journals’ recommendations and the little advice we can find in the web.

1. Understand Highlights Meaning

When I read the highlights in a paper I review, my first question was –  “do authors understand what highlights mean?”

I think if authors realized how important highlights are, they would pay a lot more attention to them. Besides the title, highlights are the first thing a person reads while searching the web for any publications in a certain field. It’s my opportunity as an author, or co-author, to capture someone attention to read my research.

Things are changing in the scientific articles publishing industry, and there is a movement toward the relevance of having more “reads” of your paper, rather than publishing in high impact factor journals.

If you understand what highlights may represent in leading people to read your paper then you realize how important it is to know their meaning.

According to Elsevier, the publisher which introduced highlights, these convey the core findings and provide readers with a quick textual overview of the article . Highlights describe the essence of the research (e.g. Results, conclusions) and highlight what is distinctive about it.

Core Findings.

Quick overview.

The essence of research. 

These are the keywords to understand highlights meaning. The challenge is how to express them in sentences shorter than a tweet…

2. Clear view of the nature of your research

When details in our research work are challenging, we tend to focus our writing describing them. Details are important, especially if challenging, because someone else might want to reproduce your experience and needs those details. But the details of your thought process, or experiments are not the nature of your research. Therefore, they shouldn’t be highlights.

The nature of your research is your WHY .

What is the ultimate question your research is trying to answer?

Why are you researching on a certain topic in the first place?

What drives your research?

Some topics are easier than others, but having a clear view of the WHY in your research is essential for writing meaningful highlights.

3. Realize people know little about your topic

I remember speaking to a small audience and feel I’m not making myself understood. This is a common flaw. Even if you have one, two or more experts in your field in front of you, when presenting an article at a conference, you should always assume there’s someone in the audience who is not an expert in your field. And when you prepare your presentation, you are speaking to this person, not the experts.

Highlights audience is the world. Therefore, you are 100% sure people which know little about your topic will read your highlights. You must write to them. 

This is a major challenge because, ideally, you should be able to express the complexity of your topic in simple, clear and concise words. A way to test these highlights is asking a friend from another field for an opinion.

4. Evidence your contribution in the field

I struggle when people literally waste their highlights with things that don’t provide the nature of their research or evidence their contribution. Let me give you an example. 

If I write 

“a hollow-cone spray is used in an impinging process occurring on a flat surface”

Why is this a highlight? Actually, this is close to what I read recently in a paper I reviewed. In all research about impinging sprays, isn’t it logical this impingement occurs in a surface? Why is this a highlight? The surface can be flat, curved, dried, wetted, structured or not, but this sentence does not explain the nature of research, nor expresses any contribution in the field. 

If we wanted to change this sentence to something more meaningful, it could be 

“Hollow-cone sprays in cooling processes address heterogeneities in temperature field.” 

The sentence is not perfect, but it has 85 characters (after 2 iterations) and contains the nature of research. It introduces the type of sprays; if they’re used in cooling processes, it means their impact on a surface is logical; and it states the purpose of that impact, which is cooling the surface and addressing heterogeneities in temperature fields, thus pointing to the challenge. Let me repeat, this is not a perfect example, but illustrates what I mean.

Another example where a small change can make a difference, at least from my viewpoint. Again, close to what I’ve read recently.

“The effect of drop dynamics, surface temperature and spray height on the liquid film formed after spray impact.”

First, it’s too long, so it needs to be shorten. But it contains what’s included in the paper’s scope, when the journal requires the core findings. Suppose the authors found these three parameters produced an effect on the outcome, a small change can resolve the issue,

“Drop dynamics, surface temperature and spray height affects liquid film formation.”

While the highlight in the first example contextualised the reader, spray cooling involves the formation of liquid films. And through this highlight, the reader knows which parameters affect the outcome and, if interested, he will read the paper to know how.

5. Be clear, concise, and go straight to the point

A non-negligible number of papers I reviewed doesn’t pay much attention to the 85 characters limitation. It forces us to seek clarity in our statements. Be concise in the words used to convey meaning. And go straight to the point because that’s what highlights are for, right? Lead the potential reader to make a quick assessment whether he should read the paper or not.

A good exercise is to distance yourself from your paper. Put yourself in the reader shoes and be critical. Would you read this paper about a topic in your field with these highlights?

6. Use simple terms

This is probably the greatest challenge. But it is important to understand what we mean by simple terms. Some research topics involve words which are not simple because their part of the lexical used in the field. Simple terms come naturally when we have a mature and clear view of our main breakthroughs.

Highlights help you refine the message in your research, evidencing only what really matters. And when we express what matters in simple terms, a reader should experience clarity and the desire to know more. 

These reflections are not exhaustive and I hope these “guidelines” motivated you to be more careful in writing meaningful highlights.

QUESTION: Are there any other suggestions, based on your experience, that would help authors write more meaningful Highlights?

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How To Write Highlights for an Academic or Scientific Paper

Posted by Rene Tetzner | Sep 7, 2021 | Paper Writing Advice | 0 |

How To Write Highlights for an Academic or Scientific Paper

How To Write Highlights for an Academic or Scientific Paper Although some academic and scientific journals have a long tradition of requesting summaries of key findings from the authors of articles accepted for publication, highlights are, for the most part, a relatively recent development in scholarly publishing. Elsevier first introduced highlights in some of its scholarly journals less than a decade ago, with its other journals and many produced by other publishers soon picking up this feature as well. The increasing popularity of highlights for research articles can be explained by their usefulness and appeal for both readers and authors in an online publishing environment. Readers are able to find and view in an extremely concise format the results presented in a published manuscript and thus determine very quickly whether they want to read the paper or not. With the Elsevier Research Highlights app, they can easily do this on their smartphones and even have the articles they wish to read sent to their inboxes. Authors benefit because their papers are given the advantage of greater visibility and discoverability, which can lead to more readers and higher citation counts. In addition, condensing the key elements of a research article into a few highlights can help an author focus more effectively on the primary contributions of his or her research.

research highlights example

The content, length and format of highlights for a research paper differ somewhat among academic and scientific journals, so one journal may simply want a bulleted list of keywords or key phrases, whereas another will require a thorough summary of the research results in the form of a brief paragraph. Elsevier journals ask for a list of bullet points that communicate the core findings of an article, conveying the essence of the research as well as its distinctiveness, but eliminating the background, methodology and other information that might appear in an abstract. Between three and five highlights are usually required, with each one not exceeding 85 characters, including spaces. The Elsevier model may be a good one to use if the journal to which you are submitting a paper indicates that highlights are desirable but provides no specific instructions or guidelines. Yet varying preferences mean that it is always wise to take a close look at the highlights in papers the journal has recently published, particularly any papers that are very similar to your own. In some cases, highlights will not be required until a paper is accepted for publication, so be sure to note when highlights should be submitted as well what form they should take.

research highlights example

Regardless of the exact format of the highlights required, they will almost certainly need to be concise in order to condense a great deal of complex information into a very little textual space. Shortening phrases, simplifying vocabulary, eliminating redundant words and using the active voice will help with observing word and character limits, and replacing long words with shorter synonyms will also help with the latter. These are good writing strategies when addressing a wide or general audience in any case, and this tends to be a desirable goal in highlights for a research paper, as does avoiding jargon and highly technical language. Do note, however, that a few journals will want authors to assume an audience of specialist readers for their highlights, in which case the guidelines will probably specify this. Keywords and key phrases are often encouraged in highlights, but nonstandard abbreviations are best avoided and must be spelled out when first used if they prove necessary. Highlights are usually written in full sentences even when they are presented as bullet points, and it is essential to write clearly and correctly if you wish to communicate effectively with potential readers and hold out the prospect of an excellent paper, so errors in spelling, grammar, punctuation and logic must be eliminated. A logical approach to highlights that begins with clarifying the nature of the research, proceeds with clear statements about the most important results and finishes with outlining the paper’s contribution to the field will generally prove successful.

research highlights example

Keeping both your readers and your research firmly in mind as you write your highlights is vital. Simplifying language and tucking everything you need to say into short and engaging highlights can lead to oversimplifying or exaggerating research findings, especially since the highlights must stand alone without any of the explanations, nuances and complications offered in the main paper. It is therefore imperative to give your highlights serious thought, ensuring that they accurately represent for readers the primary or most exciting results presented in your paper, and also that the paper itself lays emphasis on the findings prioritised in your highlights. For this reason, highlights are best drafted after the paper is written, and some authors will even go back after the highlights are written and revise their papers to achieve a clearer focus on the highlighted results. The process of writing appropriate highlights can therefore enable effective editing and help an author produce a better paper. However you choose to work at writing the highlights for your academic or scientific paper, remember that they will probably be the first thing after the title that a prospective reader encounters and they may even appear in the journal’s table of contents, so you want your highlights to make the best possible impression and lead readers to a paper that lives up to their claims.

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research highlights example

How To Write Highlights for an Academic or Scientific Paper

How To Write Highlights for an Academic or Scientific Paper Although some academic and scientific journals have a long tradition of requesting summaries of key findings from the authors of articles accepted for publication, highlights are, for the most part, a relatively recent development in scholarly publishing. Elsevier first introduced highlights in some of its scholarly journals less than a decade ago, with its other journals and many produced by other publishers soon picking up this feature as well. The increasing popularity of highlights for research articles can be explained by their usefulness and appeal for both readers and authors in an online publishing environment. Readers are able to find and view in an extremely concise format the results presented in a published manuscript and thus determine very quickly whether they want to read the paper or not. With the Elsevier Research Highlights app, they can easily do this on their smartphones and even have the articles they wish to read sent to their inboxes. Authors benefit because their papers are given the advantage of greater visibility and discoverability, which can lead to more readers and higher citation counts. In addition, condensing the key elements of a research article into a few highlights can help an author focus more effectively on the primary contributions of his or her research. The content, length and format of highlights for a research paper differ somewhat among academic and scientific journals, so one journal may simply want a bulleted list of keywords or key phrases, whereas another will require a thorough summary of the research results in the form of a brief paragraph. Elsevier journals ask for a list of bullet points that communicate the core findings of an article, conveying the essence of the research as well as its distinctiveness, but eliminating the background, methodology and other information that might appear in an abstract. Between three and five highlights are usually required, with each one not exceeding 85 characters, including spaces. The Elsevier model may be a good one to use if the journal to which you are submitting a paper indicates that highlights are desirable but provides no specific instructions or guidelines. Yet varying preferences mean that it is always wise to take a close look at the highlights in papers the journal has recently published, particularly any papers that are very similar to your own. In some cases, highlights will not be required until a paper is accepted for publication, so be sure to note when highlights should be submitted as well what form they should take. PhD Thesis Editing Services Regardless of the exact format of the highlights required, they will almost certainly need to be concise in order to condense a great deal of complex information into a very little textual space. Shortening phrases, simplifying vocabulary, eliminating redundant words and using the active voice will help with observing word and character limits, and replacing long words with shorter synonyms will also help with the latter. These are good writing strategies when addressing a wide or general audience in any case, and this tends to be a desirable goal in highlights for a research paper, as does avoiding jargon and highly technical language. Do note, however, that a few journals will want authors to assume an audience of specialist readers for their highlights, in which case the guidelines will probably specify this. Keywords and key phrases are often encouraged in highlights, but nonstandard abbreviations are best avoided and must be spelled out when first used if they prove necessary. Highlights are usually written in full sentences even when they are presented as bullet points, and it is essential to write clearly and correctly if you wish to communicate effectively with potential readers and hold out the prospect of an excellent paper, so errors in spelling, grammar, punctuation and logic must be eliminated. A logical approach to highlights that begins with clarifying the nature of the research, proceeds with clear statements about the most important results and finishes with outlining the paper’s contribution to the field will generally prove successful. Keeping both your readers and your research firmly in mind as you write your highlights is vital. Simplifying language and tucking everything you need to say into short and engaging highlights can lead to oversimplifying or exaggerating research findings, especially since the highlights must stand alone without any of the explanations, nuances and complications offered in the main paper. It is therefore imperative to give your highlights serious thought, ensuring that they accurately represent for readers the primary or most exciting results presented in your paper, and also that the paper itself lays emphasis on the findings prioritised in your highlights. For this reason, highlights are best drafted after the paper is written, and some authors will even go back after the highlights are written and revise their papers to achieve a clearer focus on the highlighted results. The process of writing appropriate highlights can therefore enable effective editing and help an author produce a better paper. However you choose to work at writing the highlights for your academic or scientific paper, remember that they will probably be the first thing after the title that a prospective reader encounters and they may even appear in the journal’s table of contents, so you want your highlights to make the best possible impression and lead readers to a paper that lives up to their claims.

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If you are in the process of preparing an article for an academic or scientific journal, or planning one for the near future, you may well be interested in a new book, Guide to Journal Publication , which is available on our Tips and Advice on Publishing Research in Journals website.

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How to write a doctoral thesis.

If you are in the process of preparing a PhD thesis for submission, or planning one for the near future, you may well be interested in the book, How to Write a Doctoral Thesis , which is available on our thesis proofreading website.

PhD Success: How to Write a Doctoral Thesis provides guidance for students familiar with English and the procedures of English universities, but it also acknowledges that many theses in the English language are now written by candidates whose first language is not English, so it carefully explains the scholarly styles, conventions and standards expected of a successful doctoral thesis in the English language.

Why Is Proofreading Important?

To improve the quality of papers.

Effective proofreading is absolutely vital to the production of high-quality scholarly and professional documents. When done carefully, correctly and thoroughly, proofreading can make the difference between writing that communicates successfully with its intended readers and writing that does not. No author creates a perfect text without reviewing, reflecting on and revising what he or she has written, and proofreading is an extremely important part of this process.

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Research Highlight

Research highlights are usually commissioned from recognized experts in a particular field. Suggestions and ideas for articles may be submitted by email .

Key aims of Research highlights are to highlight one or more exciting research article or clinical trial, recently published in Genome Medicine or another journal, and to place the new findings into the context of the current literature.

Research highlights should be around 1200 words with up to 10 references. The Abstract should be a maximum of 75 words.

Preparing your manuscript

The information below details the section headings that you should include in your manuscript and what information should be within each section.

Please note that your manuscript must include a 'Declarations' section including all of the subheadings (please see below for more information).

The title page should:

  • "A versus B in the treatment of C: a randomized controlled trial", "X is a risk factor for Y: a case control study", "What is the impact of factor X on subject Y: A systematic review"
  • or for non-clinical or non-research studies: a description of what the article reports
  • if a collaboration group should be listed as an author, please list the group name as an author. If you would like the names of the individual members of the group to be searchable through their individual PubMed records, please include this information in the “Acknowledgements” section in accordance with the instructions below
  • Large Language Models (LLMs), such as ChatGPT , do not currently satisfy our authorship criteria . Notably an attribution of authorship carries with it accountability for the work, which cannot be effectively applied to LLMs. Use of an LLM should be properly documented in the Methods section (and if a Methods section is not available, in a suitable alternative part) of the manuscript
  • indicate the corresponding author

Please minimize the use of abbreviations and do not cite references in the abstract. The abstract should briefly summarize the aim, findings or purpose of the article. The Abstract should not exceed 250 words.

Three to ten keywords representing the main content of the article.

This should contain the body of the article, and may also be broken into subsections with short, informative headings.

List of abbreviations

If abbreviations are used in the text they should be defined in the text at first use, and a list of abbreviations should be provided.

Declarations

All manuscripts must contain the following sections under the heading 'Declarations':

Ethics approval and consent to participate

Consent for publication, availability of data and materials, competing interests, authors' contributions, acknowledgements.

  • Authors' information (optional)

Please see below for details on the information to be included in these sections.

If any of the sections are not relevant to your manuscript, please include the heading and write 'Not applicable' for that section. 

Manuscripts reporting studies involving human participants, human data or human tissue must:

  • include a statement on ethics approval and consent (even where the need for approval was waived)
  • include the name of the ethics committee that approved the study and the committee’s reference number if appropriate

Studies involving animals must include a statement on ethics approval and for experimental studies involving client-owned animals, authors must also include a statement on informed consent from the client or owner.

See our editorial policies for more information.

If your manuscript does not report on or involve the use of any animal or human data or tissue, please state “Not applicable” in this section.

If your manuscript contains any individual person’s data in any form (including any individual details, images or videos), consent for publication must be obtained from that person, or in the case of children, their parent or legal guardian. All presentations of case reports must have consent for publication.

You can use your institutional consent form or our consent form if you prefer. You should not send the form to us on submission, but we may request to see a copy at any stage (including after publication).

See our editorial policies for more information on consent for publication.

If your manuscript does not contain data from any individual person, please state “Not applicable” in this section.

All manuscripts must include an ‘Availability of data and materials’ statement. Data availability statements should include information on where data supporting the results reported in the article can be found including, where applicable, hyperlinks to publicly archived datasets analysed or generated during the study. By data we mean the minimal dataset that would be necessary to interpret, replicate and build upon the findings reported in the article. We recognise it is not always possible to share research data publicly, for instance when individual privacy could be compromised, and in such instances data availability should still be stated in the manuscript along with any conditions for access.

Authors are also encouraged to preserve search strings on searchRxiv https://searchrxiv.org/ , an archive to support researchers to report, store and share their searches consistently and to enable them to review and re-use existing searches. searchRxiv enables researchers to obtain a digital object identifier (DOI) for their search, allowing it to be cited. 

Data availability statements can take one of the following forms (or a combination of more than one if required for multiple datasets):

  • The datasets generated and/or analysed during the current study are available in the [NAME] repository, [PERSISTENT WEB LINK TO DATASETS]
  • The datasets used and/or analysed during the current study are available from the corresponding author on reasonable request.
  • All data generated or analysed during this study are included in this published article [and its supplementary information files].
  • The datasets generated and/or analysed during the current study are not publicly available due [REASON WHY DATA ARE NOT PUBLIC] but are available from the corresponding author on reasonable request.
  • Data sharing is not applicable to this article as no datasets were generated or analysed during the current study.
  • The data that support the findings of this study are available from [third party name] but restrictions apply to the availability of these data, which were used under license for the current study, and so are not publicly available. Data are however available from the authors upon reasonable request and with permission of [third party name].
  • Not applicable. If your manuscript does not contain any data, please state 'Not applicable' in this section.

More examples of template data availability statements, which include examples of openly available and restricted access datasets, are available here .

BioMed Central strongly encourages the citation of any publicly available data on which the conclusions of the paper rely in the manuscript. Data citations should include a persistent identifier (such as a DOI) and should ideally be included in the reference list. Citations of datasets, when they appear in the reference list, should include the minimum information recommended by DataCite and follow journal style. Dataset identifiers including DOIs should be expressed as full URLs. For example:

Hao Z, AghaKouchak A, Nakhjiri N, Farahmand A. Global integrated drought monitoring and prediction system (GIDMaPS) data sets. figshare. 2014. http://dx.doi.org/10.6084/m9.figshare.853801

With the corresponding text in the Availability of data and materials statement:

The datasets generated during and/or analysed during the current study are available in the [NAME] repository, [PERSISTENT WEB LINK TO DATASETS]. [Reference number]  

If you wish to co-submit a data note describing your data to be published in BMC Research Notes , you can do so by visiting our submission portal . Data notes support open data and help authors to comply with funder policies on data sharing. Co-published data notes will be linked to the research article the data support ( example ).

All financial and non-financial competing interests must be declared in this section.

See our editorial policies for a full explanation of competing interests. If you are unsure whether you or any of your co-authors have a competing interest please contact the editorial office.

Please use the authors initials to refer to each authors' competing interests in this section.

If you do not have any competing interests, please state "The authors declare that they have no competing interests" in this section.

All sources of funding for the research reported should be declared. If the funder has a specific role in the conceptualization, design, data collection, analysis, decision to publish, or preparation of the manuscript, this should be declared.

The individual contributions of authors to the manuscript should be specified in this section. Guidance and criteria for authorship can be found in our editorial policies .

Please use initials to refer to each author's contribution in this section, for example: "FC analyzed and interpreted the patient data regarding the hematological disease and the transplant. RH performed the histological examination of the kidney, and was a major contributor in writing the manuscript. All authors read and approved the final manuscript."

Please acknowledge anyone who contributed towards the article who does not meet the criteria for authorship including anyone who provided professional writing services or materials.

Authors should obtain permission to acknowledge from all those mentioned in the Acknowledgements section.

See our editorial policies for a full explanation of acknowledgements and authorship criteria.

If you do not have anyone to acknowledge, please write "Not applicable" in this section.

Group authorship (for manuscripts involving a collaboration group): if you would like the names of the individual members of a collaboration Group to be searchable through their individual PubMed records, please ensure that the title of the collaboration Group is included on the title page and in the submission system and also include collaborating author names as the last paragraph of the “Acknowledgements” section. Please add authors in the format First Name, Middle initial(s) (optional), Last Name. You can add institution or country information for each author if you wish, but this should be consistent across all authors.

Please note that individual names may not be present in the PubMed record at the time a published article is initially included in PubMed as it takes PubMed additional time to code this information.

Authors' information

This section is optional.

You may choose to use this section to include any relevant information about the author(s) that may aid the reader's interpretation of the article, and understand the standpoint of the author(s). This may include details about the authors' qualifications, current positions they hold at institutions or societies, or any other relevant background information. Please refer to authors using their initials. Note this section should not be used to describe any competing interests.

Footnotes can be used to give additional information, which may include the citation of a reference included in the reference list. They should not consist solely of a reference citation, and they should never include the bibliographic details of a reference. They should also not contain any figures or tables.

Footnotes to the text are numbered consecutively; those to tables should be indicated by superscript lower-case letters (or asterisks for significance values and other statistical data). Footnotes to the title or the authors of the article are not given reference symbols.

Always use footnotes instead of endnotes.

Examples of the Vancouver reference style are shown below.

See our editorial policies for author guidance on good citation practice

Web links and URLs: All web links and URLs, including links to the authors' own websites, should be given a reference number and included in the reference list rather than within the text of the manuscript. They should be provided in full, including both the title of the site and the URL, as well as the date the site was accessed, in the following format: The Mouse Tumor Biology Database. http://tumor.informatics.jax.org/mtbwi/index.do . Accessed 20 May 2013. If an author or group of authors can clearly be associated with a web link, such as for weblogs, then they should be included in the reference.

Example reference style:

Article within a journal

Smith JJ. The world of science. Am J Sci. 1999;36:234-5.

Article within a journal (no page numbers)

Rohrmann S, Overvad K, Bueno-de-Mesquita HB, Jakobsen MU, Egeberg R, Tjønneland A, et al. Meat consumption and mortality - results from the European Prospective Investigation into Cancer and Nutrition. BMC Medicine. 2013;11:63.

Article within a journal by DOI

Slifka MK, Whitton JL. Clinical implications of dysregulated cytokine production. Dig J Mol Med. 2000; doi:10.1007/s801090000086.

Article within a journal supplement

Frumin AM, Nussbaum J, Esposito M. Functional asplenia: demonstration of splenic activity by bone marrow scan. Blood 1979;59 Suppl 1:26-32.

Book chapter, or an article within a book

Wyllie AH, Kerr JFR, Currie AR. Cell death: the significance of apoptosis. In: Bourne GH, Danielli JF, Jeon KW, editors. International review of cytology. London: Academic; 1980. p. 251-306.

OnlineFirst chapter in a series (without a volume designation but with a DOI)

Saito Y, Hyuga H. Rate equation approaches to amplification of enantiomeric excess and chiral symmetry breaking. Top Curr Chem. 2007. doi:10.1007/128_2006_108.

Complete book, authored

Blenkinsopp A, Paxton P. Symptoms in the pharmacy: a guide to the management of common illness. 3rd ed. Oxford: Blackwell Science; 1998.

Online document

Doe J. Title of subordinate document. In: The dictionary of substances and their effects. Royal Society of Chemistry. 1999. http://www.rsc.org/dose/title of subordinate document. Accessed 15 Jan 1999.

Online database

Healthwise Knowledgebase. US Pharmacopeia, Rockville. 1998. http://www.healthwise.org. Accessed 21 Sept 1998.

Supplementary material/private homepage

Doe J. Title of supplementary material. 2000. http://www.privatehomepage.com. Accessed 22 Feb 2000.

University site

Doe, J: Title of preprint. http://www.uni-heidelberg.de/mydata.html (1999). Accessed 25 Dec 1999.

Doe, J: Trivial HTTP, RFC2169. ftp://ftp.isi.edu/in-notes/rfc2169.txt (1999). Accessed 12 Nov 1999.

Organization site

ISSN International Centre: The ISSN register. http://www.issn.org (2006). Accessed 20 Feb 2007.

Dataset with persistent identifier

Zheng L-Y, Guo X-S, He B, Sun L-J, Peng Y, Dong S-S, et al. Genome data from sweet and grain sorghum (Sorghum bicolor). GigaScience Database. 2011. http://dx.doi.org/10.5524/100012 .

Figures, tables and additional files

See  General formatting guidelines  for information on how to format figures, tables and additional files.

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Submissions from medRxiv 

Authors are now able to submit manuscripts to Genome Medicine  directly from medRxiv without having to re-upload files.

Portable peer review

To reduce time spent on serial submissions and iterative reviewing, Genome Medicine offers to consider manuscripts on the basis of reviews received at other journals. We also support transfers of reviews obtained at Genome Medicine to other journals, including those outside of BMC and Springer Nature. Learn more from our peer review policy page .

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2022 Citation Impact 12.3 - 2-year Impact Factor 13.8 - 5-year Impact Factor 2.422 - SNIP (Source Normalized Impact per Paper) 4.851 - SJR (SCImago Journal Rank)

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Peer Review Taxonomy

This journal is participating in a pilot of NISO/STM's Working Group on Peer Review Taxonomy, to identify and standardize definitions and terminology in peer review practices in order to make the peer review process for articles and journals more transparent. Further information on the pilot is available here . 

The following summary describes the peer review process for this journal:

  • Identity transparency: Single anonymized
  • Reviewer interacts with: Editor
  • Review information published:  None

We welcome your feedback on this Peer Review Taxonomy Pilot. Please can you take the time to complete this short survey.

Genome Medicine

ISSN: 1756-994X

UW W Logo Program on Climate Change

  • College of the Environment Logo Text
  • University of Washington Logo Text

Write a Research Highlight

Research highlights are short layman-style summaries of peer-reviewed research papers surrounding climate and climate change.

If you are associated with the UW, and have a recent paper that informs climate, we will work with you to create a research highlight. Contact Miriam Bertram ( uwpcc@uw.edu ).

Research Highlight Format:

See a great example here.

Subtitle: one line clarification statement

Contributor of Research Highlight: you (remember to send us a picture of yourself too!)

Key Points: two or three bullet points that summarize work

Overview: two or three paragraphs that describe the significance of the work in the broad context of understanding climate change, climate impacts.  

Feel free to add a personal touch about what this research means to you, how long it took, etc.

Relevant images: these could be pictures of you/your team doing fieldwork, working on the project, etc. Include caption and credit. 

Authors & Affiliations:

Publication Date:

Publication Journal:

Cell Regeneration Cover Image

Research Highlight

Research Highlight papers focus on commentaries on emerging topics and research frontiers in stem cell and regenerative research. Typically, a Research Highlight paper should have no more than 1,200 words with a maximum of 1 figure/table/diagram and up to 10 references.

A Research Highlight contains the following sections: Abstract, Main Text and Conclusions (Optional). For invited papers, the structure is recommended but not mandatory.

Preparing your manuscript

The title page should:

  • "A versus B in the treatment of C: a randomized controlled trial", "X is a risk factor for Y: a case control study", "What is the impact of factor X on subject Y: A systematic review, A case report etc."
  • or, for non-clinical or non-research studies: a description of what the article reports
  • if a collaboration group should be listed as an author, please list the Group name as an author. If you would like the names of the individual members of the Group to be searchable through their individual PubMed records, please include this information in the “Acknowledgements” section in accordance with the instructions below
  • Large Language Models (LLMs), such as  ChatGPT, do not currently satisfy our  authorship criteria . Notably an attribution of authorship carries with it accountability for the work, which cannot be effectively applied to LLMs. Use of an LLM should be properly documented in the Methods section (and if a Methods section is not available, in a suitable alternative part) of the manuscript
  • indicate the corresponding author

The abstract should briefly summarize the aim, findings or purpose of the article. Please minimize the use of abbreviations and do not cite references in the abstract.

This should contain the body of the article, and may also be broken into subsections with short, informative headings. 

Conclusions

This should state clearly the main conclusions and provide an explanation of the importance and relevance of the case, data, opinion, database or software reported.

Declarations

All manuscripts must contain the following sections under the heading 'Declarations':

Ethics approval and consent to participate

Consent for publication

  • Availability of data and material

Competing interests

Authors' contributions

Acknowledgements

  • Authors' information (optional)

Please see below for details on the information to be included in these sections.

If any of the sections are not relevant to your manuscript, please include the heading and write 'Not applicable' for that section.

Manuscripts reporting studies involving human participants, human data or human tissue must:

  • include a statement on ethics approval and consent (even where the need for approval was waived)
  • include the name of the ethics committee that approved the study and the committee’s reference number if appropriate

Studies involving animals must include a statement on ethics approval.

See our  editorial policies  for more information.

If your manuscript does not report on or involve the use of any animal or human data or tissue, please state “Not applicable” in this section.

If your manuscript contains any individual person’s data in any form (including individual details, images or videos), consent to publish must be obtained from that person, or in the case of children, their parent or legal guardian. All presentations of case reports must have consent to publish.

You can use your institutional consent form if you prefer. You should not send the form to us on submission, but we may request to see a copy at any stage (including after publication).

See our  editorial policies  for more information on consent for publication.

If your manuscript does not contain data from any individual person, please state “Not applicable” in this section.

Availability of data and materials

All manuscripts must include an ‘Availability of data and materials’ statement. Data availability statements should include information on where data supporting the results reported in the article can be found including, where applicable, hyperlinks to publicly archived datasets analysed or generated during the study. By data we mean the minimal dataset that would be necessary to interpret, replicate and build upon the findings reported in the article. We recognise it is not always possible to share research data publicly, for instance when individual privacy could be compromised, and in such instances data availability should still be stated in the manuscript along with any conditions for access.

Data availability statements can take one of the following forms (or a combination of more than one if required for multiple datasets):

  • The datasets generated and/or analysed during the current study are available in the [NAME] repository, [PERSISTENT WEB LINK TO DATASETS]
  • The datasets used and/or analysed during the current study are available from the corresponding author on reasonable request.
  • All data generated or analysed during this study are included in this published article [and its supplementary information files].
  • The datasets generated and/or analysed during the current study are not publicly available due [REASON WHY DATA ARE NOT PUBLIC] but are available from the corresponding author on reasonable request.
  • Data sharing is not applicable to this article as no datasets were generated or analysed during the current study.
  • The data that support the findings of this study are available from [third party name] but restrictions apply to the availability of these data, which were used under license for the current study, and so are not publicly available. Data are however available from the authors upon reasonable request and with permission of [third party name].
  • Not applicable. If your manuscript does not contain any data, please state 'Not applicable' in this section.

More examples of template data availability statements, which include examples of openly available and restricted access datasets, are available here.

SpringerOpen  also requires that authors cite any publicly available data on which the conclusions of the paper rely in the manuscript. Data citations should include a persistent identifier (such as a DOI) and should ideally be included in the reference list. Citations of datasets, when they appear in the reference list, should include the minimum information recommended by DataCite and follow journal style. Dataset identifiers including DOIs should be expressed as full URLs. For example:

Hao Z, AghaKouchak A, Nakhjiri N, Farahmand A. Global integrated drought monitoring and prediction system (GIDMaPS) data sets. figshare. 2014.  http://dx.doi.org/10.6084/m9.figshare.853801

With the corresponding text in the Availability of data and materials statement:

The datasets generated during and/or analysed during the current study are available in the [NAME] repository, [PERSISTENT WEB LINK TO DATASETS]. [Reference number]

All financial and non-financial competing interests must be declared in this section.

See our  editorial policies  for a full explanation of competing interests. If you are unsure whether you or any of your co-authors have a competing interest please contact the editorial office.

If you do not have any competing interests, please state "The authors declare that they have no competing interests" in this section.

All sources of funding for the research reported should be declared. The role of the funding body in the design of the study and collection, analysis, and interpretation of data and in writing the manuscript should be declared.

The individual contributions of authors to the manuscript should be specified in this section. Guidance and criteria for authorship can be found in our  editorial policies .

Please acknowledge anyone who contributed towards the article who does not meet the criteria for authorship including anyone who provided professional writing services or materials.

Authors should obtain permission to acknowledge from all those mentioned in the Acknowledgements section.

See our  editorial policies  for a full explanation of acknowledgements and authorship criteria.

If you do not have anyone to acknowledge, please write "Not applicable" in this section.

Group authorship (for manuscripts involving a collaboration group): if you would like the names of the individual members of a collaboration Group to be searchable through their individual PubMed records, please ensure that the title of the collaboration Group is included on the title page and in the submission system and also include collaborating author names as the last paragraph of the “Acknowledgements” section. Please add authors in the format First Name, Middle initial(s) (optional), Last Name. You can add institution or country information for each author if you wish, but this should be consistent across all authors.

Please note that individual names may not be present in the PubMed record at the time a published article is initially included in PubMed as it takes PubMed additional time to code this information.

Authors' information

This section is optional.

You may choose to use this section to include any relevant information about the author(s) that may aid the reader's interpretation of the article, and understand the standpoint of the author(s). This may include details about the authors' qualifications, current positions they hold at institutions or societies, or any other relevant background information. Please refer to authors using their initials. Note this section should not be used to describe any competing interests.

Footnotes should be designated within the text using a superscript number. It is not allowed to use footnotes for references/citations.

Examples of the Vancouver reference style are shown below. 

See our editorial policies for author guidance on good citation practice.

Web links and URLs: All web links and URLs, including links to the authors' own websites, should be given a reference number and included in the reference list rather than within the text of the manuscript. They should be provided in full, including both the title of the site and the URL, as well as the date the site was accessed, in the following format: The Mouse Tumor Biology Database. http://tumor.informatics.jax.org/mtbwi/index.do . Accessed 20 May 2013. If an author or group of authors can clearly be associated with a web link, such as for weblogs, then they should be included in the reference.

Example reference style:

Article within a journal

Smith JJ. The world of science. Am J Sci. 1999;36:234-5.

Article within a journal (no page numbers)

Rohrmann S, Overvad K, Bueno-de-Mesquita HB, Jakobsen MU, Egeberg R, Tjønneland A, et al. Meat consumption and mortality - results from the European Prospective Investigation into Cancer and Nutrition. BMC Medicine. 2013;11:63.

Article within a journal by DOI

Slifka MK, Whitton JL. Clinical implications of dysregulated cytokine production. Dig J Mol Med. 2000; doi:10.1007/s801090000086.

Article within a journal supplement

Frumin AM, Nussbaum J, Esposito M. Functional asplenia: demonstration of splenic activity by bone marrow scan. Blood 1979;59 Suppl 1:26-32.

Book chapter, or an article within a book

Wyllie AH, Kerr JFR, Currie AR. Cell death: the significance of apoptosis. In: Bourne GH, Danielli JF, Jeon KW, editors. International review of cytology. London: Academic; 1980. p. 251-306.

OnlineFirst chapter in a series (without a volume designation but with a DOI)

Saito Y, Hyuga H. Rate equation approaches to amplification of enantiomeric excess and chiral symmetry breaking. Top Curr Chem. 2007. doi:10.1007/128_2006_108.

Complete book, authored

Blenkinsopp A, Paxton P. Symptoms in the pharmacy: a guide to the management of common illness. 3rd ed. Oxford: Blackwell Science; 1998.

Online document

Doe J. Title of subordinate document. In: The dictionary of substances and their effects. Royal Society of Chemistry. 1999. http://www.rsc.org/dose/title of subordinate document. Accessed 15 Jan 1999.

Online database

Healthwise Knowledgebase. US Pharmacopeia, Rockville. 1998. http://www.healthwise.org. Accessed 21 Sept 1998.

Supplementary material/private homepage

Doe J. Title of supplementary material. 2000. http://www.privatehomepage.com. Accessed 22 Feb 2000.

University site

Doe, J: Title of preprint. http://www.uni-heidelberg.de/mydata.html (1999). Accessed 25 Dec 1999.

Doe, J: Trivial HTTP, RFC2169. ftp://ftp.isi.edu/in-notes/rfc2169.txt (1999). Accessed 12 Nov 1999.

Organization site

ISSN International Centre: The ISSN register. http://www.issn.org (2006). Accessed 20 Feb 2007.

Dataset with persistent identifier

Zheng L-Y, Guo X-S, He B, Sun L-J, Peng Y, Dong S-S, et al. Genome data from sweet and grain sorghum (Sorghum bicolor). GigaScience Database. 2011. http://dx.doi.org/10.5524/100012 .

General formatting information

Manuscripts must be written in concise English. For help on scientific writing, or preparing your manuscript in English, please see Springer's  Author Academy .

Quick points:

  • Use double line spacing
  • Include line and page numbering
  • Use SI units: Please ensure that all special characters used are embedded in the text, otherwise they will be lost during conversion to PDF
  • Do not use page breaks in your manuscript

File formats

The following word processor file formats are acceptable for the main manuscript document:

  • Microsoft word (DOC, DOCX)
  • Rich text format (RTF)
  • TeX/LaTeX 

Please note: editable files are required for processing in production. If your manuscript contains any non-editable files (such as PDFs) you will be required to re-submit an editable file if your manuscript is accepted.

For more information, see ' Preparing figures ' below.

Additional information for TeX/LaTeX users

You are encouraged to use the Springer Nature LaTeX template when preparing a submission. A PDF of your manuscript files will be compiled during submission using pdfLaTeX and TexLive 2021. All relevant editable source files must be uploaded during the submission process. Failing to submit these source files will cause unnecessary delays in the production process.  

Style and language

For editors and reviewers to accurately assess the work presented in your manuscript you need to ensure the English language is of sufficient quality to be understood. If you need help with writing in English you should consider:

  • Getting a fast, free online grammar check .
  • Visiting the English language tutorial which covers the common mistakes when writing in English.
  • Asking a colleague who is proficient in English to review your manuscript for clarity.
  • Using a professional language editing service where editors will improve the English to ensure that your meaning is clear and identify problems that require your review. Two such services are provided by our affiliates Nature Research Editing Service and American Journal Experts . SpringerOpen authors are entitled to a 10% discount on their first submission to either of these services. To claim 10% off English editing from Nature Research Editing Service, click here . To claim 10% off American Journal Experts, click here .

Please note that the use of a language editing service is not a requirement for publication in Cell Regeneration and does not imply or guarantee that the article will be selected for peer review or accepted.  为便于编辑和评审专家准确评估您稿件中陈述的研究工作,您需要确保文稿英语语言质量足以令人理解。如果您需要英文写作方面的帮助,您可以考虑:

  • 获取快速、免费的在线  语法检查 。
  • 查看一些有关英语写作中常见语言错误的 教程 。
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Value of the Influence of Research Highlights on Academic Papers

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research highlights example

  • Yue Liu 8 ,
  • Dejun Zheng 8 ,
  • Haichen Zhou 9 &
  • Shaoxiong Fu 8  

Part of the book series: Communications in Computer and Information Science ((CCIS,volume 1593))

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This study explores the differences between highlight papers and non-highlight papers from the perspective of academic influence as a crucial insight for evaluating scientific research. Three dimensions are considered: journals, papers, and research highlights. We selected 8 academic journals in the field of library and information science, which are published by Elsevier and indexed by SSCI, and analyzed 5,020 academic papers published therein from 2011 to 2020. The results of our empirical study demonstrate that all journals acknowledge the existence of research highlights, although not all online academic papers provide them. In recent years, the number of highlight papers has increased annually, and more importantly, the proportion has also grown steadily. The ETA square coefficient of citations is higher for highlight papers compared to non-highlight papers. Furthermore, in the training of the innovation recognition model, the effect of the training model that uses the research highlights of academic papers with high citation frequency is better, although the PRF value has a smaller difference.

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School of Information Management, Nanjing Agricultural University, Nanjing, 210095, Jiangsu, China

Yue Liu, Dejun Zheng & Shaoxiong Fu

Chengdu Library of the Chinese Academy of Sciences, Chengdu, 610041, Sichuan, China

Haichen Zhou

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University of Kaohsiung, Kaohsiung, Taiwan

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FernUniversität in Hagen, Hagen, Germany

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Liu, Y., Zheng, D., Zhou, H., Fu, S. (2022). Value of the Influence of Research Highlights on Academic Papers. In: Uden, L., Ting, IH., Feldmann, B. (eds) Knowledge Management in Organisations. KMO 2022. Communications in Computer and Information Science, vol 1593. Springer, Cham. https://doi.org/10.1007/978-3-031-07920-7_5

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December 22, 2020

2020 Research Highlights — Basic Research Insights

Noteworthy advances in fundamental research.

With NIH support, scientists across the United States and around the world conduct wide-ranging research to discover ways to enhance health, lengthen life, and reduce illness and disability. Groundbreaking NIH-funded research often receives top scientific honors. In 2020, these honors included one of NIH’s own scientists and another NIH-supported scientist who received Nobel Prizes . Here’s just a small sample of the NIH-supported research accomplishments in 2020.

Full 2020 NIH Research Highlights List

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Novel Coronavirus SARS-CoV-2

Understanding SARS-CoV-2

The first reports of an unknown, sometimes fatal respiratory infection emerged from Wuhan, China in late 2019. NIH researchers quickly moved to understand the source of that infection, a novel coronavirus called SARS-CoV-2. By February, they produced a detailed picture of the virus spike protein , which allows the virus to infect human cells. This helped to identify targets for potential vaccines and treatments. Further work gave detail into how the virus enters and exits cells, which may help guide new approaches to combatting infections and stopping transmission. A genomic analysis helped explain why SARS-CoV-2 is more deadly than many other coronaviruses. Immune system studies showed how existing immune cells may help account for the wide range of symptoms among the infected and shed light on the antibody levels and immune cells needed to protect against SARS-CoV-2 .

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Group of senior adults on a walk through the park on a sunny day.

Exercise-induced protein may reverse age-related cognitive decline

Physical activity can play an important role in maintaining cognitive health, but it hasn’t been clear why. Researchers identified an exercise-induced protein that generated new brain cells and improved memory in mice. The protein was also found in higher levels in the blood and plasma of older adults who were active. The findings suggest new approaches to combat age-related cognitive decline.

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Pain suppression neurons in mouse brain.

Scientists find new pain-suppression center in the brain

More than 50 million Americans suffer from chronic pain, and many are prescribed opioid medications as treatment. Researchers are searching for more effective treatments for chronic pain. A study identified a group of neurons in mice that blunt pain by dampening the activity of multiple pain-processing regions of the brain. The neurons could be promising targets for new non-addictive therapies for chronic pain.

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Poor immune response impairs diabetic wound healing

Diabetes can impair the skin’s ability to heal itself. Even small cuts on the feet can develop into diabetic foot ulcers—chronic, non-healing wounds that are vulnerable to infection. These ulcers are a major cause of lower limb amputations, disability, and death in people with diabetes. Researchers found that diabetic foot ulcers don’t recruit the immune cells needed for normal wound healing. Understanding this impaired immune response could lead to better therapies.

20200204-hair.jpg

Mature man looking in bathroom mirror at the gray hair in his beard

How stress causes gray hair

A study confirmed that stress can turn hair prematurely gray—and discovered how. Scientists found that stress affects the stem cells responsible for regenerating hair pigment. Chemicals involved in the body’s fight-or-flight response cause permanent loss of these stem cells so that new hair appears gray or white. The findings give insights for future research into how stress affects stem cells and tissue regeneration.

20200512-govd.jpg

3D SCAPE Imaging of Mouse Olfactory Epithelium

How the nose decodes complex odors

The nose contains millions of specialized neurons that allow it to smell different odors. Simple odors activate a particular combination of neurons that send a coded message to the brain. Researchers used an advanced 3D imaging technique in mice to reveal how receptors in the nose help decode the smell of complex odor mixtures. The findings shed light on how the brain perceives odors and may help reveal why some diseases cause a loss of smell.

20200616-hair-less-yellow.jpg

Skin with hairs

Hairy human skin generated from stem cells

Scientists have been able to grow human skin outside the body for over 40 years. However, skin grown in cultures lacked the embedded structures, like hair follicles and sweat glands, found in real skin. Researchers were able to create hair-growing skin from human stem cells and graft it to mice. The lab-grown skin could aid in the study of skin diseases and skin reconstruction after burns and wounds.

20200609-cochlea.jpg

Sensory hair cells in newborn mouse cochlea

Researchers create developmental map of mouse cochlea

Hearing involves thousands of tiny hair cells inside the cochlea, a snail-shaped organ in the inner ear. In humans, hair cells can’t regenerate when they’re damaged. Loud sounds, disease, injury, and aging can all damage hair cells and result in permanent hearing loss. Scientists mapped how these sensory cells develop in the mouse cochlea. Understanding cochlear development could help researchers working on therapies for several forms of hearing loss.

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The scientific community has much to be proud of, making countless inspirational breakthroughs, advancing knowledge, and impacting upon global issues the world over, giving us groundbreaking research in clinical medicine and immunology, climate change, politics, and technological innovation. 

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Artificial intelligence in strategy

Can machines automate strategy development? The short answer is no. However, there are numerous aspects of strategists’ work where AI and advanced analytics tools can already bring enormous value. Yuval Atsmon is a senior partner who leads the new McKinsey Center for Strategy Innovation, which studies ways new technologies can augment the timeless principles of strategy. In this episode of the Inside the Strategy Room podcast, he explains how artificial intelligence is already transforming strategy and what’s on the horizon. This is an edited transcript of the discussion. For more conversations on the strategy issues that matter, follow the series on your preferred podcast platform .

Joanna Pachner: What does artificial intelligence mean in the context of strategy?

Yuval Atsmon: When people talk about artificial intelligence, they include everything to do with analytics, automation, and data analysis. Marvin Minsky, the pioneer of artificial intelligence research in the 1960s, talked about AI as a “suitcase word”—a term into which you can stuff whatever you want—and that still seems to be the case. We are comfortable with that because we think companies should use all the capabilities of more traditional analysis while increasing automation in strategy that can free up management or analyst time and, gradually, introducing tools that can augment human thinking.

Joanna Pachner: AI has been embraced by many business functions, but strategy seems to be largely immune to its charms. Why do you think that is?

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Yuval Atsmon: You’re right about the limited adoption. Only 7 percent of respondents to our survey about the use of AI say they use it in strategy or even financial planning, whereas in areas like marketing, supply chain, and service operations, it’s 25 or 30 percent. One reason adoption is lagging is that strategy is one of the most integrative conceptual practices. When executives think about strategy automation, many are looking too far ahead—at AI capabilities that would decide, in place of the business leader, what the right strategy is. They are missing opportunities to use AI in the building blocks of strategy that could significantly improve outcomes.

I like to use the analogy to virtual assistants. Many of us use Alexa or Siri but very few people use these tools to do more than dictate a text message or shut off the lights. We don’t feel comfortable with the technology’s ability to understand the context in more sophisticated applications. AI in strategy is similar: it’s hard for AI to know everything an executive knows, but it can help executives with certain tasks.

When executives think about strategy automation, many are looking too far ahead—at AI deciding the right strategy. They are missing opportunities to use AI in the building blocks of strategy.

Joanna Pachner: What kind of tasks can AI help strategists execute today?

Yuval Atsmon: We talk about six stages of AI development. The earliest is simple analytics, which we refer to as descriptive intelligence. Companies use dashboards for competitive analysis or to study performance in different parts of the business that are automatically updated. Some have interactive capabilities for refinement and testing.

The second level is diagnostic intelligence, which is the ability to look backward at the business and understand root causes and drivers of performance. The level after that is predictive intelligence: being able to anticipate certain scenarios or options and the value of things in the future based on momentum from the past as well as signals picked in the market. Both diagnostics and prediction are areas that AI can greatly improve today. The tools can augment executives’ analysis and become areas where you develop capabilities. For example, on diagnostic intelligence, you can organize your portfolio into segments to understand granularly where performance is coming from and do it in a much more continuous way than analysts could. You can try 20 different ways in an hour versus deploying one hundred analysts to tackle the problem.

Predictive AI is both more difficult and more risky. Executives shouldn’t fully rely on predictive AI, but it provides another systematic viewpoint in the room. Because strategic decisions have significant consequences, a key consideration is to use AI transparently in the sense of understanding why it is making a certain prediction and what extrapolations it is making from which information. You can then assess if you trust the prediction or not. You can even use AI to track the evolution of the assumptions for that prediction.

Those are the levels available today. The next three levels will take time to develop. There are some early examples of AI advising actions for executives’ consideration that would be value-creating based on the analysis. From there, you go to delegating certain decision authority to AI, with constraints and supervision. Eventually, there is the point where fully autonomous AI analyzes and decides with no human interaction.

Because strategic decisions have significant consequences, you need to understand why AI is making a certain prediction and what extrapolations it’s making from which information.

Joanna Pachner: What kind of businesses or industries could gain the greatest benefits from embracing AI at its current level of sophistication?

Yuval Atsmon: Every business probably has some opportunity to use AI more than it does today. The first thing to look at is the availability of data. Do you have performance data that can be organized in a systematic way? Companies that have deep data on their portfolios down to business line, SKU, inventory, and raw ingredients have the biggest opportunities to use machines to gain granular insights that humans could not.

Companies whose strategies rely on a few big decisions with limited data would get less from AI. Likewise, those facing a lot of volatility and vulnerability to external events would benefit less than companies with controlled and systematic portfolios, although they could deploy AI to better predict those external events and identify what they can and cannot control.

Third, the velocity of decisions matters. Most companies develop strategies every three to five years, which then become annual budgets. If you think about strategy in that way, the role of AI is relatively limited other than potentially accelerating analyses that are inputs into the strategy. However, some companies regularly revisit big decisions they made based on assumptions about the world that may have since changed, affecting the projected ROI of initiatives. Such shifts would affect how you deploy talent and executive time, how you spend money and focus sales efforts, and AI can be valuable in guiding that. The value of AI is even bigger when you can make decisions close to the time of deploying resources, because AI can signal that your previous assumptions have changed from when you made your plan.

Joanna Pachner: Can you provide any examples of companies employing AI to address specific strategic challenges?

Yuval Atsmon: Some of the most innovative users of AI, not coincidentally, are AI- and digital-native companies. Some of these companies have seen massive benefits from AI and have increased its usage in other areas of the business. One mobility player adjusts its financial planning based on pricing patterns it observes in the market. Its business has relatively high flexibility to demand but less so to supply, so the company uses AI to continuously signal back when pricing dynamics are trending in a way that would affect profitability or where demand is rising. This allows the company to quickly react to create more capacity because its profitability is highly sensitive to keeping demand and supply in equilibrium.

Joanna Pachner: Given how quickly things change today, doesn’t AI seem to be more a tactical than a strategic tool, providing time-sensitive input on isolated elements of strategy?

Yuval Atsmon: It’s interesting that you make the distinction between strategic and tactical. Of course, every decision can be broken down into smaller ones, and where AI can be affordably used in strategy today is for building blocks of the strategy. It might feel tactical, but it can make a massive difference. One of the world’s leading investment firms, for example, has started to use AI to scan for certain patterns rather than scanning individual companies directly. AI looks for consumer mobile usage that suggests a company’s technology is catching on quickly, giving the firm an opportunity to invest in that company before others do. That created a significant strategic edge for them, even though the tool itself may be relatively tactical.

Joanna Pachner: McKinsey has written a lot about cognitive biases  and social dynamics that can skew decision making. Can AI help with these challenges?

Yuval Atsmon: When we talk to executives about using AI in strategy development, the first reaction we get is, “Those are really big decisions; what if AI gets them wrong?” The first answer is that humans also get them wrong—a lot. [Amos] Tversky, [Daniel] Kahneman, and others have proven that some of those errors are systemic, observable, and predictable. The first thing AI can do is spot situations likely to give rise to biases. For example, imagine that AI is listening in on a strategy session where the CEO proposes something and everyone says “Aye” without debate and discussion. AI could inform the room, “We might have a sunflower bias here,” which could trigger more conversation and remind the CEO that it’s in their own interest to encourage some devil’s advocacy.

We also often see confirmation bias, where people focus their analysis on proving the wisdom of what they already want to do, as opposed to looking for a fact-based reality. Just having AI perform a default analysis that doesn’t aim to satisfy the boss is useful, and the team can then try to understand why that is different than the management hypothesis, triggering a much richer debate.

In terms of social dynamics, agency problems can create conflicts of interest. Every business unit [BU] leader thinks that their BU should get the most resources and will deliver the most value, or at least they feel they should advocate for their business. AI provides a neutral way based on systematic data to manage those debates. It’s also useful for executives with decision authority, since we all know that short-term pressures and the need to make the quarterly and annual numbers lead people to make different decisions on the 31st of December than they do on January 1st or October 1st. Like the story of Ulysses and the sirens, you can use AI to remind you that you wanted something different three months earlier. The CEO still decides; AI can just provide that extra nudge.

Joanna Pachner: It’s like you have Spock next to you, who is dispassionate and purely analytical.

Yuval Atsmon: That is not a bad analogy—for Star Trek fans anyway.

Joanna Pachner: Do you have a favorite application of AI in strategy?

Yuval Atsmon: I have worked a lot on resource allocation, and one of the challenges, which we call the hockey stick phenomenon, is that executives are always overly optimistic about what will happen. They know that resource allocation will inevitably be defined by what you believe about the future, not necessarily by past performance. AI can provide an objective prediction of performance starting from a default momentum case: based on everything that happened in the past and some indicators about the future, what is the forecast of performance if we do nothing? This is before we say, “But I will hire these people and develop this new product and improve my marketing”— things that every executive thinks will help them overdeliver relative to the past. The neutral momentum case, which AI can calculate in a cold, Spock-like manner, can change the dynamics of the resource allocation discussion. It’s a form of predictive intelligence accessible today and while it’s not meant to be definitive, it provides a basis for better decisions.

Joanna Pachner: Do you see access to technology talent as one of the obstacles to the adoption of AI in strategy, especially at large companies?

Yuval Atsmon: I would make a distinction. If you mean machine-learning and data science talent or software engineers who build the digital tools, they are definitely not easy to get. However, companies can increasingly use platforms that provide access to AI tools and require less from individual companies. Also, this domain of strategy is exciting—it’s cutting-edge, so it’s probably easier to get technology talent for that than it might be for manufacturing work.

The bigger challenge, ironically, is finding strategists or people with business expertise to contribute to the effort. You will not solve strategy problems with AI without the involvement of people who understand the customer experience and what you are trying to achieve. Those who know best, like senior executives, don’t have time to be product managers for the AI team. An even bigger constraint is that, in some cases, you are asking people to get involved in an initiative that may make their jobs less important. There could be plenty of opportunities for incorpo­rating AI into existing jobs, but it’s something companies need to reflect on. The best approach may be to create a digital factory where a different team tests and builds AI applications, with oversight from senior stakeholders.

The big challenge is finding strategists to contribute to the AI effort. You are asking people to get involved in an initiative that may make their jobs less important.

Joanna Pachner: Do you think this worry about job security and the potential that AI will automate strategy is realistic?

Yuval Atsmon: The question of whether AI will replace human judgment and put humanity out of its job is a big one that I would leave for other experts.

The pertinent question is shorter-term automation. Because of its complexity, strategy would be one of the later domains to be affected by automation, but we are seeing it in many other domains. However, the trend for more than two hundred years has been that automation creates new jobs, although ones requiring different skills. That doesn’t take away the fear some people have of a machine exposing their mistakes or doing their job better than they do it.

Joanna Pachner: We recently published an article about strategic courage in an age of volatility  that talked about three types of edge business leaders need to develop. One of them is an edge in insights. Do you think AI has a role to play in furnishing a proprietary insight edge?

Yuval Atsmon: One of the challenges most strategists face is the overwhelming complexity of the world we operate in—the number of unknowns, the information overload. At one level, it may seem that AI will provide another layer of complexity. In reality, it can be a sharp knife that cuts through some of the clutter. The question to ask is, Can AI simplify my life by giving me sharper, more timely insights more easily?

Joanna Pachner: You have been working in strategy for a long time. What sparked your interest in exploring this intersection of strategy and new technology?

Yuval Atsmon: I have always been intrigued by things at the boundaries of what seems possible. Science fiction writer Arthur C. Clarke’s second law is that to discover the limits of the possible, you have to venture a little past them into the impossible, and I find that particularly alluring in this arena.

AI in strategy is in very nascent stages but could be very consequential for companies and for the profession. For a top executive, strategic decisions are the biggest way to influence the business, other than maybe building the top team, and it is amazing how little technology is leveraged in that process today. It’s conceivable that competitive advantage will increasingly rest in having executives who know how to apply AI well. In some domains, like investment, that is already happening, and the difference in returns can be staggering. I find helping companies be part of that evolution very exciting.

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