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The Case Study of Vanitas Manga Unveils Volume 11 Cover

The Case Study of Vanitas (Vanitas no Carte) series revealed the cover illustration for Volume 11 of the manga, which is set to release on April 22, 2024. The regular edition features an illustration of Vanitas holding a plate of Tarte Tatin with Noe and Murr behind him. Meanwhile, the special edition features the “Archiviste girl” with Noe at the back. The manga series is written and illustrated by Jun Mochizuki.

As described by Square Enix , the plot of the 11th manga volume of The Case Study of Vanitas is as follows (spoilers ahead): “Another “fang that reveals blood.” After the fierce battle that Mikhail set up, Vanitas and his friends take a moment to rest. Behind the scenes, Count Saint-Germain approaches the Archiviste girl —This is a “story.” The promised hope and despair of vampires, humans, and half-breeds are set in motion once again. Volume 11 of a steampunk fantasy woven by human and vampire buddies that unravels memories.”

Special illustrations and postcards will also be given away as bonus gifts in selected stores in Japan. Pre-orders for Volume 11 of The Case Study of Vanitas manga are still available on Amazon , Rakuten , and Square Enix. Additionally, the special edition will include a 128-page “Brocante” booklet featuring comments and rough drawings of Vanitas and Noe’s character designs, taken from the author’s original 2000-page sketchbook before the series began in 2015.

Also Read: The Case Study of Vanitas Manga Returns From Hiatus on May 22 The Case Study of Vanitas Episode 24 – A Profoundly Momentous Finale

The Case Study of Vanitas  is a steampunk-vampire-themed manga series by Jun Mozuchi. It has been serialized in Square Enix’s Monthly Gangan Joker magazine since 2015. Studio BONES animated the series in 2021 and has a total of 24 episodes. Afterward, the series went on hiatus in May 2022 and returned a year later in May 2023. Yen Press  releases the English versions of the manga and describes the plot: “ Rumors revolving around The Book of Vanitas, a clockwork grimoire of dubious reputation, draw Noé, a young vampire in search of a friend’s salvation, to Paris. What awaits him in the City of Flowers, however, is not long hours treading the pavement or rifling through dusty bookshops in search of the tome. Instead, his quarry comes to him…in the arms of a man claiming to be a vampire doctor! Thrust into a conflict that threatens the peace between humans and vampires, will Noé cast in his lot with the curious and slightly unbalanced Vanitas and his quest to save vampirekind? “

Source:  Square Enix , Gangan Joker X, Jun Mochizuki X (Formerly Twitter) ©Jun Mochizuki/SQUARE ENIX

Carla Carreon

Hello, I'm Carla Bianca! Just a fluffy bean with introverted energies. Reading, watching, drawing, playing Genshin, and sleeping mostly take up my day. Someday, I will have my manga library and Rimuru shrine!

Eiichiro Oda Releases Some of the Oldest One Piece Art in Existence

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Measles — United States, January 1, 2020–March 28, 2024

Weekly / April 11, 2024 / 73(14);295–300

Adria D. Mathis, MSPH 1 ; Kelley Raines, MPH 1 ; Nina B. Masters, PhD 1 ; Thomas D. Filardo, MD 1 ; Gimin Kim, MS 1 ; Stephen N. Crooke, PhD 1 ; Bettina Bankamp, PhD 1 ; Paul A. Rota, PhD 1 ; David E. Sugerman, MD 1 ( View author affiliations )

What is already known about this topic?

Although endemic U.S. measles was declared eliminated in 2000, measles importations continue to occur. Prolonged outbreaks during 2019 threatened the U.S. measles elimination status.

What is added by this report?

During January 1, 2020–March 28, 2024, a total of 338 U.S. measles cases were reported; 29% of these cases occurred during the first quarter of 2024, almost all in persons who were unvaccinated or whose vaccination status was unknown. As of the end of 2023, U.S. measles elimination status was maintained.

What are the implications for public health practice?

Risk for widespread U.S. measles transmission remains low because of high population immunity. Enhanced efforts are needed to increase routine U.S. vaccination coverage, encourage vaccination before international travel, identify communities at risk for measles transmission, and rapidly investigate suspected measles cases to reduce cases and complications of measles.

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Measles is a highly infectious febrile rash illness and was declared eliminated in the United States in 2000. However, measles importations continue to occur, and U.S. measles elimination status was threatened in 2019 as the result of two prolonged outbreaks among undervaccinated communities in New York and New York City. To assess U.S. measles elimination status after the 2019 outbreaks and to provide context to understand more recent increases in measles cases, CDC analyzed epidemiologic and laboratory surveillance data and the performance of the U.S. measles surveillance system after these outbreaks. During January 1, 2020–March 28, 2024, CDC was notified of 338 confirmed measles cases; 97 (29%) of these cases occurred during the first quarter of 2024, representing a more than seventeenfold increase over the mean number of cases reported during the first quarter of 2020–2023. Among the 338 reported cases, the median patient age was 3 years (range = 0–64 years); 309 (91%) patients were unvaccinated or had unknown vaccination status, and 336 case investigations included information on ≥80% of critical surveillance indicators. During 2020–2023, the longest transmission chain lasted 63 days. As of the end of 2023, because of the absence of sustained measles virus transmission for 12 consecutive months in the presence of a well-performing surveillance system, U.S. measles elimination status was maintained. Risk for widespread U.S. measles transmission remains low because of high population immunity. However, because of the increase in cases during the first quarter of 2024, additional activities are needed to increase U.S. routine measles, mumps, and rubella vaccination coverage, especially among close-knit and undervaccinated communities. These activities include encouraging vaccination before international travel and rapidly investigating suspected measles cases.

Introduction

Measles is a highly infectious acute, febrile rash illness with a >90% secondary attack rate among susceptible contacts ( 1 ). High national 2-dose coverage with the measles, mumps, and rubella (MMR) vaccine led to the declaration of U.S. measles elimination* in 2000 ( 2 ). However, this elimination status was threatened in 2019 because of two prolonged outbreaks among undervaccinated communities in New York and New York City; these outbreaks accounted for 29% of all reported cases during 2001–2019 ( 2 ). To assess U.S. measles elimination status after the 2019 outbreaks and to provide context for understanding more recent increases in measles cases in 2024, † CDC assessed the epidemiologic and laboratory-based surveillance of measles in the United States and the performance of the U.S. measles surveillance system during January 1, 2020–March 28, 2024.

Reporting and Classification of Measles Cases

Confirmed measles cases § ( 1 ) are reported to CDC by state health departments through the National Notifiable Disease Surveillance System and directly (by email or telephone) to the National Center for Immunization and Respiratory Diseases. Measles cases are classified by the Council of State and Territorial Epidemiologists as import-associated if they were internationally imported, epidemiologically linked to an imported case, or had viral genetic evidence of an imported measles genotype ( 1 ); cases with no epidemiologic or virologic link to an imported case are classified as having an unknown source ( 1 ). For this analysis, unique sequences were defined as those differing by at least one nucleotide in the N-450 sequence (the 450 nucleotides encoding the carboxyl-terminal 150 nucleoprotein amino acids) based on the standard World Health Organization (WHO) recommendations for describing sequence variants ¶ ( 3 ). Unvaccinated patients were classified as eligible for vaccination if they were not vaccinated according to Advisory Committee on Immunization Practices recommendations ( 4 ). A well-performing surveillance system was defined as one with ≥80% of cases meeting each of the following three criteria: classified as import-associated, reported with complete information on at least eight of 10 critical surveillance indicators (i.e., place of residence, sex, age, occurrence of fever and rash, date of rash onset, vaccination status, travel history, hospitalization, transmission setting, and whether the case was outbreak-related) ( 5 ), and laboratory-confirmed.

Assessment of Chains of Transmission

Cases were classified into chains of transmission on the basis of known epidemiologic linkages: isolated (single) cases, two-case chains (two epidemiologically linked cases), and outbreaks (three or more epidemiologically linked cases). The potential for missed cases within two-case chains and outbreaks was assessed by measuring the interval between measles rash onset dates in each chain; chains with more than one maximum incubation period (21 days) between cases could indicate a missing case in the chain. This activity was reviewed by CDC, deemed not research, and was conducted consistent with applicable federal law and CDC policy.**

Reported Measles Cases and Outbreaks

CDC was notified of 338 confirmed measles cases with rash onset during January 1, 2020–March 28, 2024 ( Figure ); cases occurred in 30 jurisdictions. During 2020, 12 of 13 cases preceded the commencement of COVID-19 mitigation efforts in March 2020. Among the 170 cases reported during 2021 and 2022, 133 (78%) were associated with distinct outbreaks: 47 (96%) of 49 cases in 2021 occurred among Afghan evacuees temporarily housed at U.S. military bases during Operation Allies Welcome, and 86 (71%) of 121 cases in 2022 were associated with an outbreak in central Ohio. During 2023, 28 (48%) of 58 cases were associated with four outbreaks. As of March 28, 2024, a total of 97 cases have been reported in 2024, representing 29% of all 338 measles cases reported during January 1, 2020–March 28, 2024, and more than a seventeenfold increase over the mean number of cases reported during the first quarter of 2020–2023 (five cases).

Characteristics of Reported Measles Cases

The median patient age was 3 years (range = 0–64 years); more than one half of cases (191; 58%) occurred in persons aged 16 months–19 years ( Table ). Overall, 309 (91%) patients were unvaccinated (68%) or had unknown vaccination status (23%); 29 (9%) had previously received ≥1 MMR vaccine dose. Among the 309 cases among unvaccinated persons or persons with unknown vaccination status, 259 (84%) patients were eligible for vaccination, 40 (13%) were aged 6–11 months and therefore not recommended for routine MMR vaccination, and 10 (3%) were ineligible for MMR because they were aged <6 months. †† Among 155 (46%) hospitalized measles patients, 109 (70%) cases occurred in persons aged <5 years; 142 (92%) hospitalized patients were unvaccinated or had unknown vaccination status. No measles-associated deaths were reported to CDC.

Imported Measles Cases

Among all 338 cases, 326 (96%) were associated with an importation; 12 (4%) had an unknown source. Among the 326 import-associated cases, 200 (61%) occurred among U.S. residents who were eligible for vaccination but who were unvaccinated or whose vaccination status was unknown. Among 93 (28%) measles cases that were directly imported from other countries, 34 (37%) occurred in foreign visitors, and 59 (63%) occurred in U.S. residents, 53 (90%) of whom were eligible for vaccination but were unvaccinated or whose vaccination status was unknown. One (2%) case in a U.S. resident occurred in a person too young for vaccination, two (3%) in persons who had previously received 1 MMR vaccine dose, and three (5%) in persons who had previously received 2 MMR vaccine doses. The most common source for internationally imported cases during the study period were the Eastern Mediterranean (48) and African (24) WHO regions. During the first quarter of 2024, a total of six internationally imported cases were reported from the European and South-East Asia WHO regions, representing a 50% increase over the mean number of importations from these regions during 2020–2023 (mean of two importations per year from each region).

Surveillance Quality Indicators

Overall, all but two of the 338 case investigations included information on ≥80% of the critical surveillance indicators; those two case investigations included information on 70% of critical surveillance indicators. Date of first case report to a health department was available for 219 (65%) case investigations; 127 (58%) cases were reported to health departments on or before the day of rash onset (IQR = 4 days before to 3 days after). Overall, 314 (93%) measles cases were laboratory confirmed, including 16 (5%) by immunoglobulin M (serologic) testing alone and 298 (95%) by real-time reverse transcription–polymerase chain reaction (rRT-PCR). Among 298 rRT-PCR–positive specimens, 221 (74%) were successfully genotyped: 177 (80%) were genotype B3, and 44 (20%) were genotype D8. Twenty-two distinct sequence identifiers (DSIds) ( 3 ) for genotype B3 and 13 DSIds for genotype D8 were detected (Supplementary Figure, https://stacks.cdc.gov/view/cdc/152776 ). The longest period of detection for any DSId was 15 weeks (DSId 8346).

Chains of Transmission

The 338 measles cases were categorized into 92 transmission chains (Table); 62 (67%) were isolated cases, 10 (11%) were two-case chains, and 20 (22%) were outbreaks of three or more cases. Seven (35%) of 20 outbreaks occurred during 2024. §§ The median outbreak size was six cases (range = three–86 cases) and median duration of transmission was 20 days (range = 6–63 days). Among the 30 two-case chains and outbreaks, more than one maximum incubation period (21 days) did not elapse between any two cases.

Because of the absence of endemic measles virus transmission for 12 consecutive months in the presence of a well-performing surveillance system, as of the end of 2023, measles elimination has been maintained in the United States. U.S. measles elimination reduces the number of cases, deaths, and costs that would occur if endemic measles transmission were reestablished. Investigation of almost all U.S. measles cases reported since January 2020 were import-associated, included complete information on critical surveillance variables, were laboratory-confirmed by rRT-PCR, and underwent genotyping; these findings indicate that the U.S. measles surveillance system is performing well. A variety of transmission chain sizes were detected, including isolated cases, suggesting that sustained measles transmission would be rapidly detected. However, the rapid increase in the number of reported measles cases during the first quarter of 2024 represents a renewed threat to elimination.

Most measles importations were cases among persons traveling to and from countries in the Eastern Mediterranean and African WHO regions; these regions experienced the highest reported measles incidence among all WHO regions during 2021–2022 ( 6 ). During November 2022–October 2023, the number of countries reporting large or disruptive outbreaks increased by 123%, from 22 to 49. Global estimates suggest that first-dose measles vaccination coverage had declined from 86% in 2019 to 83% in 2022, leaving almost 22 million children aged <1 year susceptible to measles ( 6 ).

As has been the case in previous postelimination years ( 7 ), most imported measles cases occurred among unvaccinated U.S. residents. Increasing global measles incidence and decreasing vaccination coverage will increase the risk for importations into U.S. communities, as has been observed during the first quarter of 2024, further supporting CDC’s recommendation for persons to receive MMR vaccine before international travel ( 4 ).

Maintaining high national and local MMR vaccination coverage remains central to sustaining measles elimination. Risk for widespread U.S. measles transmission remains low because of high population immunity; however, national 2-dose MMR vaccination coverage has remained below the Healthy People 2030 target of 95% (the estimated population-level immunity necessary to prevent sustained measles transmission) ( 8 ) for 3 consecutive years, leaving approximately 250,000 kindergarten children susceptible to measles each year ( 9 ). Furthermore, 2-dose MMR vaccination coverage estimates in 12 states and the District of Columbia were <90%, and during the 2022–23 school year, exemption rates among kindergarten children exceeded 5% in 10 states ( 9 ). Clusters of unvaccinated persons placed communities at risk for large outbreaks, as occurred during the central Ohio outbreak in 2022: 94% of measles patients were unvaccinated and 42% were hospitalized ( 10 ). Monitoring MMR vaccination coverage at county and zip code levels could help public health agencies identify undervaccinated communities for targeted interventions to improve vaccination coverage while preparing for possible measles outbreaks. As of March 28, 2024, a total of 97 confirmed measles cases have been reported in the United States in 2024, compared with a mean of five cases during the first quarter of each year during 2020–2023. Similar to cases reported during 2020–2023, most cases reported during 2024 occurred among patients aged <20 years who were unvaccinated or whose vaccination status was unknown, and were associated with an importation. Rapid detection of cases, prompt implementation of control measures, and maintenance of high national measles vaccination coverage, including improving coverage in undervaccinated populations, is essential to preventing measles and its complications and to maintaining U.S. elimination status.

Limitations

The findings in this report are subject to at least three limitations. First, importations might have been underreported: 4% of reported cases during the study period had no known source. Second, case investigations resulting in discarded measles cases (i.e., a diagnosis of measles excluded) are not nationally reportable, which limits the ability to directly evaluate the sensitivity of measles case investigations. However, surveillance remains sufficiently sensitive to detect isolated cases and outbreaks, and robust molecular epidemiology provides further evidence supporting the absence of sustained measles transmission in the United States. Finally, the date of first case report to a health department was not available for 35% of case investigations.

Implications for Public Health Practice

The U.S. measles elimination status will continue to be threatened by global increases in measles incidence and decreases in global, national, and local measles vaccination coverage. Because of high population immunity, the risk of widespread measles transmission in the United States remains low; however, efforts are needed to increase routine MMR vaccination coverage, encourage vaccination before international travel, identify communities at risk for measles transmission, and rapidly investigate suspected measles cases to maintain elimination.

Corresponding author: Adria D. Mathis, [email protected] .

1 Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, CDC.

All authors have completed and submitted the International Committee of Medical Journal Editors form for disclosure of potential conflicts of interest. Stephen N. Crooke reports institutional support from PATH. No other potential conflicts of interest were disclosed.

* Elimination is defined as the absence of endemic measles virus transmission in a defined geographic area for ≥12 months in the presence of a well-performing surveillance system.

† https://emergency.cdc.gov/han/2024/han00504.asp

§ A confirmed measles case was defined as an acute febrile rash illness with laboratory confirmation or direct epidemiologic linkage to a laboratory-confirmed case. Laboratory confirmation was defined as detection of measles virus–specific nucleic acid from a clinical specimen using real-time reverse transcription–polymerase chain reaction or a positive serologic test for measles immunoglobulin M antibody.

¶ Genotyping was performed at CDC and at the Vaccine Preventable Disease Reference Centers of the Association of Public Health Laboratories.

** 45 C.F.R. part 46.102(l)(2), 21 C.F.R. part 56; 42 U.S.C. Sect. 241(d); 5 U.S.C. Sect. 552a; 44 U.S.C. Sect. 3501 et seq.

†† MMR vaccine is not licensed for use in persons aged <6 months.

§§ At the time of this report, six measles outbreaks have ended, and one outbreak is ongoing. A measles outbreak is considered to be over when no new cases have been identified during two incubation periods (42 days) since the rash onset in the last outbreak-related case.

• Gastañaduy PA, Redd SB, Clemmons NS, et al. Measles [Chapter 7]. In: Manual for the surveillance of vaccine-preventable diseases. Atlanta, GA: US Department of Health and Human Services, CDC; 2023. https://www.cdc.gov/vaccines/pubs/surv-manual/chpt07-measles.html
• Mathis AD, Clemmons NS, Redd SB, et al. Maintenance of measles elimination status in the United States for 20 years despite increasing challenges. Clin Infect Dis 2022;75:416–24. https://doi.org/10.1093/cid/ciab979 PMID:34849648
• Williams D, Penedos A, Bankamp B, et al. Update: circulation of active genotypes of measles virus and recommendations for use of sequence analysis to monitor viral transmission. Weekly Epidemiologic Record 2022;97(39):481–92. https://reliefweb.int/report/world/weekly-epidemiological-record-wer-30-september-2022-vol-97-no-39-2022-pp-481-492-enfr
• McLean HQ, Fiebelkorn AP, Temte JL, Wallace GS; CDC. Prevention of measles, rubella, congenital rubella syndrome, and mumps, 2013: summary recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR Recomm Rep 2013;62(No. RR-4):1–34. PMID:23760231
• World Health Organization. Measles: vaccine preventable diseases surveillance standards. Geneva, Switzerland: World Health Organization; 2018. https://www.who.int/publications/m/item/vaccine-preventable-diseases-surveillance-standards-measles
• Minta AA, Ferrari M, Antoni S, et al. Progress toward measles elimination—worldwide, 2000–2022. MMWR Morb Mortal Wkly Rep 2023;72:1262–8. https://doi.org/10.15585/mmwr.mm7246a3 PMID:37971951
• Lee AD, Clemmons NS, Patel M, Gastañaduy PA. International importations of measles virus into the United States during the postelimination era, 2001–2016. J Infect Dis 2019;219:1616–23. https://doi.org/10.1093/infdis/jiy701 PMID:30535027
• Truelove SA, Graham M, Moss WJ, Metcalf CJE, Ferrari MJ, Lessler J. Characterizing the impact of spatial clustering of susceptibility for measles elimination. Vaccine 2019;37:732–41. https://doi.org/10.1016/j.vaccine.2018.12.012 PMID:30579756
• Seither R, Yusuf OB, Dramann D, Calhoun K, Mugerwa-Kasujja A, Knighton CL. Coverage with selected vaccines and exemption from school vaccine requirements among children in kindergarten—United States, 2022–23 school year. MMWR Morb Mortal Wkly Rep 2023;72:1217–24. https://doi.org/10.15585/mmwr.mm7245a2 PMID:37943705
• Tiller EC, Masters NB, Raines KL, et al. Notes from the field: measles outbreak—central Ohio, 2022–2023. MMWR Morb Mortal Wkly Rep 2023;72:847–9. https://doi.org/10.15585/mmwr.mm7231a3 PMID:37535476

FIGURE . Confirmed measles cases, by month of rash onset (N = 338) — United States, January 1, 2020–March 28, 2024

Abbreviations: IgM = immunoglobulin M; rRT-PCR = real-time reverse transcription–polymerase chain reaction; WHO = World Health Organization. * A case resulting from exposure to measles virus outside the United States as evidenced by at least some of the exposure period (7–21 days before rash onset) occurring outside the United States and rash onset occurring within 21 days of entering the United States without known exposure to measles during that time. † A case in a transmission chain epidemiologically linked to an internationally imported case. § A case for which an epidemiologic link to an internationally imported case was not identified, but for which viral sequence data indicate an imported measles genotype (i.e., a genotype that is not detected in the United States with a pattern indicative of endemic transmission). ¶ A case for which an epidemiologic or virologic link to importation or to endemic transmission within the United States cannot be established after a thorough investigation. ** Percentage is percentage of international importations. Four cases among persons who traveled to both the Eastern Mediterranean and African regions and one case in a person who traveled to both the Eastern Mediterranean and European regions were counted twice. †† Place of residence, sex, age or date of birth, fever and rash, date of rash onset, vaccination status, travel history, hospitalization, transmission setting, and whether the case was outbreak related. §§ Includes 65 cases among patients who received both positive rRT-PCR and positive IgM results. ¶¶ Percentage is percentage of total chains.

Suggested citation for this article: Mathis AD, Raines K, Masters NB, et al. Measles — United States, January 1, 2020–March 28, 2024. MMWR Morb Mortal Wkly Rep 2024;73:295–300. DOI: http://dx.doi.org/10.15585/mmwr.mm7314a1 .

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‘Shiki’ And 7 Other Vampire-Themed Anime Series For A Blood Curdling Binge-Watch

V ampires are timeless, quite literally. Thanks to the blend of darkness, romance and supernatural intrigue, vampire-based stories have caught audiences’ attention and have been an intriguing subject over all these years.

Hits like the Twilight franchise and series like True Blood and The Vampire Diaries , created a tremendous wave of vampire-fans, giving rise to a demand for the stories based on these mythical creatures.

Similarly, vampires have been quite popular in the anime universe for over two decades. From classic adaptations to innovative original creations, vampire-based anime series have enthralled audiences with their rich lore, complex characters and thrilling storylines. Hint: Jojo’s Bizarre Aventure .

With their immortal allure and insatiable thirst for blood, vampires have become iconic figures within the medium, inspiring countless stories exploring the night’s darkness and the eternal struggle between light and shadow.

From Blood Lad , Shiki, Undead Murder Farce  and Blood C to Rosario+Vampire , let’s dive into the world of vampire-based anime series , where the boundaries between the living and the undead blur.

Love vampires? These are the best anime series based on the mythical creature

Jojo’s bizzare adventure (2012).

Jojo’s Bizarre Adventure follows the adventures of the Joestar family across multiple generations, each with its protagonist, often referred to as Jojo. The plot begins in the late 19th century with Jonathan Joestar, the first Jojo, as he clashes with the vampire Dio Brando, who becomes his bitter enemy after being adopted into the Joestar family. Their battle sets the stage for a centuries-long feud that spans generations.

Subsequent parts of the series introduce new Jojos and their allies, as they face off against a wide array of foes, including vampires, ancient gods and spirits. Throughout their journeys, the Jojos must master their newfound powers, forge alliances and confront their inner demons to protect their loved ones and defeat evil.

IMDb rating: 8.5/10

Undead Murder Farce (2021)

Taking place in an alternate historical period known as the Belle Époque era in the late 19th century, where humans coexist with supernatural beings like vampires and oni, Undead Murder Farce revolves around Tsugaru Shinuchi, an experimental half-oni nicknamed the Oni Slayer. He embarks on a quest alongside an immortal woman named Aya Rindo and her devoted servant, Shizuku Hasei.

Tsugaru seeks a method to prolong his life, while Aya, who exists only as a disembodied head, longs for death. Upon realising that a wealthy foreigner with an ‘M’ marked on his cane is responsible for their plight, they travel from Japan to Europe to confront him. In their pursuit, they aim to locate Aya’s missing body, hoping it will lead them to their target. As they navigate through Europe, they encounter various supernatural enigmas, with Tsugaru adopting the alias ‘The Cage User’, reflecting the birdcage he carries containing Aya’s head.

IMDb rating: 7.9/10

Blood+ (2005)

High school anime Blood+ centres around Saya Otonashi, an ordinary girl living in Okinawa. However, her life takes a drastic turn when she discovers she is a unique being known as a Chiropteran Queen. Chiropterans are vampiric creatures that prey on humans, and Saya possesses the power to hunt and kill them.

A mysterious organisation called the Red Shield, dedicated to combating the Chiropterans and protecting humanity from their threat, aids her. Alongside her companions, including the Haji and the members of the Red Shield, Saya embarks on a journey to eliminate the Chiropterans and uncover the truth about her own identity and past.

She confronts numerous challenges including powerful Chiropteran mutants, shadowy conspiracies and personal revelations about her origins. Along the way, she forms deep bonds with her allies and learns to harness her powers to fulfil her destiny as the Chiropteran Queen.

IMDb rating: 7.6/10

The Case Study of Vanitas (2021)

Set in an alternate steampunk version of 19th-century Paris, The Case Study of Vanitas follows a young vampire named Noé Archiviste who heads on a journey to find a mysterious book called The Book of Vanitas . This book is said to possess immense power and is rumoured to be capable of curing vampires of their afflictions. During his quest, Noé encounters a vampire named Vanitas, who claims to be the keeper of the book.

However, Vanitas is not just an ordinary vampire , he possesses a unique grimoire known as the ‘Grimoire of Vanitas’, which allows him to manipulate the essence of vampires, known as ‘The Curse’. Despite their initial mistrust of each other, Noé and Vanitas form an unlikely alliance as they look into the mysteries surrounding the Book of Vanitas and the origins of vampires. As the story progresses, the duo uncover dark secrets about the true nature of vampires, the history of their world and the tragic pasts that haunt them both.

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How to watch the ‘blue exorcist’ anime in order of chronology, shiki (2010).

Shiki is set in a small and remote village called Sotoba, nestled in the mountains of Japan. Life in Sotoba is peaceful and uneventful until a mysterious epidemic begins to spread, causing a series of unexplained deaths. As the death toll rises, the villagers become increasingly alarmed and paranoid, fearing that a supernatural force is at work.

Natsuno Yuuki is a sceptical and introverted teenager who is initially indifferent to the strange occurrences in Sotoba. However, when his friend unexpectedly dies and returns as one of the undead, he is caught in the mystery surrounding the epidemic. As Natsuno investigates the deaths, he discovers that the village is plagued by vampires known as Shiki, who are preying on the villagers under darkness.

Blood Lad (2013)

In Blood Lad , Staz Charlie Blood is a powerful vampire who rules over the Demon World’s Eastern District. Unlike most vampires who feed on humans, Staz has an obsession with Japanese culture, particularly anime, manga and video games. He spends his days lazing around and indulging in his hobbies.

However, Staz’s mundane existence is disrupted when a human girl named Fuyumi Yanagi accidentally wanders into the Demon World through a portal. Unfortunately, Fuyumi is killed by a carnivorous plant shortly after her arrival. Surprisingly, Fuyumi becomes a ghost rather than passing on to the afterlife. Intrigued by Fuyumi’s condition and smitten by her resemblance to a character from his favourite manga, Staz vows to find a way to resurrect her.

IMDb rating: 7/10

Rosario + Vampire (2008)

Rosario + Vampire follows Tsukune Aono, an ordinary high school student who fails to gain admission to any local high school. Desperate to continue his education, Tsukune’s parents enrol him in Yokai Academy, a boarding school for monsters hidden from human society.

Upon arriving at Yokai Academy, Tsukune quickly discovers the truth about his new classmates and the school’s curriculum. To blend in and avoid suspicion, he must keep his humanity a secret while navigating the challenges of attending a school filled with monsters. He then befriends several female students, including the beautiful vampire Moka Akashiya.

As Tsukune becomes entangled in the supernatural world of Yokai Academy, he finds himself drawn into various adventures and battles against dangerous monsters and dark forces.

IMDb rating: 6.9/10

Blood C (2011)

Saya Kisaragi is an ordinary high school girl living in the quiet town of Ukishima. Unknown to her classmates and friends, she is a skilled swordswoman tasked with protecting her town from monstrous creatures known as Elder Bairns.

As the dark anime series progresses, her peaceful life is shattered when she begins to experience strange and disturbing visions. These visions hint at a dark conspiracy lurking beneath the surface of Ukishima, involving her friends, her family and even herself.

IMDb rating: 6.2/10

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(Hero and feature image credit: Courtesy IMDb)

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