current medical research and opinion

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Medical research articles from across Nature Portfolio

Medical research involves research in a wide range of fields, such as biology, chemistry, pharmacology and toxicology with the goal of developing new medicines or medical procedures or improving the application of those already available. It can be viewed as encompassing preclinical research (for example, in cellular systems and animal models) and clinical research (for example, clinical trials).

An explainable foundation model for drug repurposing

A foundation model leverages large-scale medical knowledge to repurpose drugs for diseases that currently lack approved treatments, and provides explanations to support clinicians’ decisions.

• Alaa Bessadok
• Francesca Grisoni

Disease background influences fate of transplanted stem cells

Gene-edited stem cells can be used in regenerative therapies to treat diverse genetic diseases. Tracking the output of these cells over time reveals a commitment to lineages that meet disease-specific needs.

• Vijay G. Sankaran

Ultra-high-field MRI for fast imaging of the human brain at mesoscale resolution

Very high-resolution images of the human brain obtained in vivo in a few minutes with MRI at an ultra-high magnetic field of 11.7 T reveal exquisite details. Biological and behavioral tests confirm the safety of the method, opening the door for human brain exploration at mesoscale resolution.

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• Epidemiology
• Experimental models of disease
• Genetics research
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• Paediatric research
• Preclinical research
• Stem-cell research
• Clinical trial design
• Translational research

Latest Research and Reviews

Phase II Study of Irinotecan, Trifluridine/tipiracil (TAS-102) plus Bevacizumab as a Later-line Therapy for Patients with Metastatic Colorectal Cancer (mCRC): a prospective single-center explorative study

• Wenwei Yang
• Yongkun Sun

Social determinants of health and surgical outcomes of minimally invasive radical prostatectomy: a national population-based study

• Spencer M. Mossack
• Antonio Franco
• Riccardo Autorino

Prevalence and predictors of detrusor underactivity and bladder outlet obstruction in women with lower urinary tract symptoms

• Chin-Jui Wu
• Sheng-Mou Hsiao
• Ho-Hsiung Lin

Preliminary study on the effects of boysenberry juice intake on brown adipose tissue activity in healthy adults

• Ryo Furuuchi
• Satoshi Kato
• Tohru Minamino

Identification of diagnostic challenges in RP1 Alu insertion and strategies for overcoming them

• Jong Kwon Lee
• Ja-Hyun Jang

The no-retina-touch technique: vitrectomy and platelet-rich plasma in the treatment of lamellar macular hole. New insights into pathogenesis

• Federico Ricardi
• Francesco Gelormini
• Michele Reibaldi

News and Comment

Psychedelic therapies: healing for the wrong reasons.

• Eduardo Ekman Schenberg
• Christine Hauskeller
• Franklin King IV

Bile acid transport inhibitors in paediatric hepatology: more than just an itch

Apical sodium-dependent bile acid transporter inhibitors have revolutionized care for children with genetic cholestasis. This Clinical Outlook discusses how this new class of drugs came into clinical practice and how they might benefit transplant-free survival for a multitude of indications.

• Tamir Diamond
• Binita M. Kamath

Is the stereoisomer R-MDMA a safer version of MDMA?

• Gillinder Bedi

Lack of benefit from extended lymphadenectomy in muscle-invasive bladder cancer

• Diana Romero

Machine learning algorithms: why the cup occasionally appears half-empty

• Richard J. Woodman

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Current Medical Research and Opinion

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• Medicine (miscellaneous)

Taylor and Francis Ltd.

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03007995, 14734877

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[email protected]

The set of journals have been ranked according to their SJR and divided into four equal groups, four quartiles. Q1 (green) comprises the quarter of the journals with the highest values, Q2 (yellow) the second highest values, Q3 (orange) the third highest values and Q4 (red) the lowest values.

The SJR is a size-independent prestige indicator that ranks journals by their 'average prestige per article'. It is based on the idea that 'all citations are not created equal'. SJR is a measure of scientific influence of journals that accounts for both the number of citations received by a journal and the importance or prestige of the journals where such citations come from It measures the scientific influence of the average article in a journal, it expresses how central to the global scientific discussion an average article of the journal is.

Evolution of the number of published documents. All types of documents are considered, including citable and non citable documents.

This indicator counts the number of citations received by documents from a journal and divides them by the total number of documents published in that journal. The chart shows the evolution of the average number of times documents published in a journal in the past two, three and four years have been cited in the current year. The two years line is equivalent to journal impact factor ™ (Thomson Reuters) metric.

Evolution of the total number of citations and journal's self-citations received by a journal's published documents during the three previous years. Journal Self-citation is defined as the number of citation from a journal citing article to articles published by the same journal.

Evolution of the number of total citation per document and external citation per document (i.e. journal self-citations removed) received by a journal's published documents during the three previous years. External citations are calculated by subtracting the number of self-citations from the total number of citations received by the journal’s documents.

International Collaboration accounts for the articles that have been produced by researchers from several countries. The chart shows the ratio of a journal's documents signed by researchers from more than one country; that is including more than one country address.

Not every article in a journal is considered primary research and therefore "citable", this chart shows the ratio of a journal's articles including substantial research (research articles, conference papers and reviews) in three year windows vs. those documents other than research articles, reviews and conference papers.

Ratio of a journal's items, grouped in three years windows, that have been cited at least once vs. those not cited during the following year.

Evolution of the percentage of female authors.

Evolution of the number of documents cited by public policy documents according to Overton database.

Evolution of the number of documents related to Sustainable Development Goals defined by United Nations. Available from 2018 onwards.

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Current Medical Research and Opinion

Journal Abbreviation: CURR MED RES OPIN Journal ISSN: 0300-7995

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Pharma pours millions into the NHS for non-research work—but we don’t know what the money is being spent on

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Chemotherapy among patients with triple negative breast cancer based on integrated mRNA-lncRNA signature

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GLP-1 receptor agonists before upper gastrointestinal endoscopy and risk of pulmonary aspiration or discontinuation of procedure

Prioritising primary care patients with unexpected weight loss for cancer investigation, paternal metformin use and risk of congenital malformations in offspring, intense simplified strategy for newly diagnosed type 2 diabetes in patients with severe hyperglycaemia, reading and conducting instrumental variable studies, progress of nations in the organisation of, and structures for, kidney care delivery, rainfall events and daily mortality across 645 global locations, strategies and tactics to reduce the impact of healthcare on climate change.

Environmental changes in South Sudan are changing the fabric of people’s lives and steering humanitarian operations

Klimaseniorinnen v switzerland: the european court of human rights leads the way on climate action, medical school fitness to practise: the challenge of competing interests and responsibilities, cop29 must move from stalling to action, david oliver: we need doctors to take on leadership roles—so why do we bring them down, scarlett mcnally: designing patient centred clinics around space, time, and staff, helen salisbury: the broken nhs and how to fix it, hpv vaccination has dramatically reduced inequalities in cervical cancer, but the most deprived groups remain at highest risk.

Should patients treated with direct oral anticoagulants receive intravenous thrombolytics for acute ischaemic stroke?

How to get started in medical leadership, navigating surgery with adhd and autism, the impact of increasing temperatures due to climate change on infectious diseases, switching from inhaled to intravenous general anaesthesia, sodium-glucose cotransporter-2 (sglt-2) inhibitors for adults with chronic kidney disease: a clinical practice guideline, optimising inhaled therapy for patients with asthma, acute aortic syndrome, management of atrial fibrillation in older adults, stevens-johnson syndrome/toxic epidermal necrolysis: initial assessment, global health crises: gaza and mpox, when is enough, enough humanitarian rights and protection for children in conflict settings must be revisited.

Protecting the lives of children in conflicts requires changes to the rules of engagement

Poliovirus is detected in Gaza as “dire” conditions ignite fears of infectious diseases spreading

WHO has warned that there is a “high risk” of polio spreading in Gaza and beyond, after variant poliovirus type 2 was detected in Gaza’s sewage

Mpox outbreaks in Africa—we must avert another failure of global solidarity

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New research from BMJ Medicine finds that multimorbidity is prevalent in the emergency department population

All cause and cause specific mortality in 15-24-year-olds in Denmark

Mortality in young people in Denmark is consistently socially patterned across measures of socioeconomic position and causes of deaths including natural and unnatural deaths caused by accidents, suicides, and homicides

Development and validation of a prognostic model to predict birth weight

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Shifting influence: the unaccountable millions paid by industry to healthcare organisations

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Covid-19: Researcher blows the whistle on data integrity issues in Pfizer’s vaccine trial

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• ISSN: 2589-8779 (Medium online) | 2589-8760 (Medium Print)
• Journal title: Journal of Current Medical Research and Opinion
• Abbreviation: J Current Med Res Opinion
• First Year published: 2018
• Current Issue Vol. 7 No. 10 (2024)
• Frequency: Monthly| 12 per year)

Journal of Current Medical Research and Opinion is a  peer-reviewed, international journal for the rapid publication of original research on new and existing drugs and therapies,  and post-marketing investigations. Equivalence, safety and efficacy/effectiveness studies are especially encouraged. 

The aim of Journal of Current Medical Research and Opinion is to provide ethical, unbiased and rapid publication of quality content that is validated by rigorous peer review. Journal aim is to serve the information needs of the clinical medicine community, to help translate medical advances into patient care and be a leader in transparency/disclosure by facilitating a collaborative and honest approach to publication.

Aims and scope:

CMRO  is the flagship medical journal. An open access, open peer-reviewed general medical journal,  CMRO outstanding and influential research in all areas of clinical practice, translational medicine, medical and health advances, public health, global health, policy, and general topics of interest to the biomedical and sociomedical professional communities. We also publish stimulating debates and reviews as well as unique forum articles and concise tutorials.  

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Volume / Issue / Month: Volume 7 Issue 09  September 2024

Initial Submission: 26.07.2024 - 26.08.2024

Submit Offline:  [email protected]

We publish innovative original research papers, review articles, case reports and short communications dealing with all the medical specialties like Anatomy, Physiology, Biochemistry, Pharmacology, Pathology, Forensic medicine, Microbiology, Community Medicine, Ophthalmology, Otorhinolaryngology, Internal Medicine, General Surgery, Paediatrics, Obstetrics and Gynaecology, Orthopaedics, Psychiatry, Radiology, Pulmonary Medicine, Dermatology and Venereal diseases, Infectious Diseases, Anaesthesia, Cardiology, Diabetes, Cancer research, Endocrinology, Urology, Neurosurgery, Geriatric Medicine, Gastroenterology, Neurology, Nephrology, Dentistry and Medical education.

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Vol. 7 No. 10 (2024)

Original Research

Health promotion lifestyle in university students.

Online First: October 12, 2024 | DOI : 10.52845/CMRO/2024/7-10-4 | Google Scholar | Abstract : 20 Cite this: Journal of Current Medical Research and Opinion , Vol. 7 No. 10 (2024), October 12, 2024 , Page 3682-3689

Screening of Metabolites Produced by Pathogenic Escherichia coli and Evaluation of its Antimicrobial Activity

Online First: October 3, 2024 | DOI : 10.52845/CMRO/2024/7-10-1 | Google Scholar | Abstract : 22 Cite this: Journal of Current Medical Research and Opinion , Vol. 7 No. 10 (2024), October 3, 2024 , Page 3652-3662

Unveiling informal leadership dynamics: A Social Network Analysis (SNA) of nursing staff in North India’s apex hospital

Online First: October 12, 2024 | DOI : 10.52845/CMRO/2024/7-10-2 | Google Scholar | Abstract : 5 Cite this: Journal of Current Medical Research and Opinion , Vol. 7 No. 10 (2024), October 12, 2024 , Page 3663-3677

Review Article

A short review on increase burden of documentation vs patient care for nursing.

Online First: October 12, 2024 | DOI : 10.52845/CMRO/2024/7-10-3 | Google Scholar | Abstract : 11 Cite this: Journal of Current Medical Research and Opinion , Vol. 7 No. 10 (2024), October 12, 2024 , Page 3678-3681

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In Tied Presidential Race, Harris and Trump Have Contrasting Strengths, Weaknesses

2. issues and the 2024 election, table of contents.

• Other findings: An uncertain election outcome, the more critical candidate, Trump and the 2020 election
• Voting preferences among demographic groups
• Support for Harris, Trump among voters and nonvoters in recent elections
• How Harris and Trump supporters see their vote
• Do voters think it’s clear who will win?
• Most voters cite several issues as very important to their vote
• Changes in confidence in candidates on issues, following Biden’s departure from race 
• Do voters see the candidates as ‘too personally critical’?
• Do the candidates make you feel proud, hopeful, uneasy or angry?
• How the candidates make Harris and Trump supporters feel
• How men and women view the impact of the candidates’ genders
• Views of the candidates’ races and ethnicities
• Views of the candidates’ ages among younger and older voters
• Views of the values and goals of the other candidate’s supporters
• Should the president work with the opposing party in Congress?
• Top economic concerns: Food and consumer prices, housing costs
• Acknowledgments
• The American Trends Panel survey methodology

As concerns around the state of the economy and inflation continue, about eight-in-ten registered voters (81%) say the economy will be very important to their vote in the 2024 presidential election.

While the economy is the top issue among voters, a large majority (69%) cite at least five of the 10 issues asked about in the survey as very important to their vote.

There are wide differences between voters who support Harris and Trump when it comes to the issues.

Among Trump supporters, the economy (93%), immigration (82%) and violent crime (76%) are the leading issues. Just 18% of Trump supporters say racial and ethnic inequality is very important. And even fewer say climate change is very important (11%).

For Harris supporters, issues such as health care (76%) and Supreme Court appointments (73%) are of top importance. Large majorities also cite the economy (68%) and abortion (67%) as very important to their vote in the election.

Most voters cite several issues as very important to their vote this November. Very few – just 5% – say only one issue or no issues are highly important.

Majorities of both Harris supporters (71%) and Trump supporters (69%) say at least five of 10 issues included in the survey are very important to their vote.

Harris supporters are more likely than Trump supporters to say most of the issues included are very important. About a third of Harris supporters (32%) say at least eight of 10 issues are very important, compared with 17% of Trump supporters.

Top voting issues: 2020 versus 2024

While the economy has long been a top issue for voters – and continues to be one today – other issues have become increasingly important for voters over the past four years.

Immigration

About six-in-ten voters (61%) today say immigration is very important to their vote – a 9 percentage point increase from the 2020 presidential election and 13 points higher than during the 2022 congressional elections.

Immigration is now a much more important issue for Republican voters in particular: 82% of Trump supporters say it is very important to their vote in the 2024 election, up 21 points from 2020.

About four-in-ten Harris supporters (39%) say immigration is very important to their vote. This is 8 points higher than the share of Democratic congressional supporters who said this in 2022, but lower than the 46% of Biden supporters who cited immigration as very important four years ago.

In August 2020, fewer than half of voters (40%) said abortion was a very important issue to their vote. At the time, Trump voters (46%) were more likely than Biden voters (35%) to say it mattered a great deal.

Following the Supreme Court’s decision to overturn Roe v. Wade , opinions about abortion’s importance as a voting issue shifted. Today, 67% of Harris supporters call the issue very important – nearly double the share of Biden voters who said this four years ago, though somewhat lower than the share of midterm Democratic voters who said this in 2022 (74%). And about a third of Trump supporters (35%) now say abortion is very important to their vote – 11 points lower than in 2020.

Confidence in Harris and Trump on top issues

Voters have more confidence in Trump than Harris on economic, immigration and foreign policies. Half or more voters say they are at least somewhat confident in Trump to make good decisions in these areas, while smaller shares (45% each) say this about Harris.

In contrast, voters have more confidence in Harris than Trump to make good decisions about abortion policy and to effectively address issues around race. Just over half of voters have confidence in Harris on these issues, while 44% have confidence in Trump on these issues.

Trump holds a slight edge over Harris for handling law enforcement and criminal justice issues (51% Trump, 47% Harris). Voters are equally confident in Harris and Trump to select good nominees for the Supreme Court (50% each).

Fewer than half of voters say they are very or somewhat confident in either candidate to bring the country closer together (41% are confident in Harris, 36% in Trump). And voters express relatively little confidence in Trump (37%) or Harris (32%) to reduce the influence of money in politics.

Since Biden dropped out of the presidential race in July , there has been movement on how confident voters are in the candidates to address issues facing the country.

Abortion policy

In July, 48% of voters were confident in Biden to make good decisions about abortion policy. Today, 55% of voters are confident in Harris to do the same.

Harris currently has an 11-point advantage over Trump on voters’ confidence to handle abortion policy decisions.

Immigration policy

Voters also express more confidence in Harris to make wise decisions about immigration policy than they did for Biden before he withdrew from the race. Today, 45% are confident in Harris on this issue; in July, 35% said this about Biden.

While Trump’s advantage over Harris on immigration policy is less pronounced than it was over Biden, he continues to hold a 7-point edge. Voters are as confident in his ability to make wise decisions about immigration policy as they were in July (52%).

Foreign and economic policies

Harris has also improved over Biden in voters’ confidence to make good decisions about foreign and economic policies. Currently, 45% of voters are confident in Harris on each of these issues.

In July, 39% had confidence in Biden to make good foreign policy decisions, while a similar share (40%) had confidence in him on economic policy.

Trump holds an edge over Harris on both of these issues, though both are somewhat narrower than the advantage he had over Biden on these issues in July.

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• Donald Trump
• Election 2024
• Kamala Harris
• Political Issues
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• Voter Demographics

Harris, Trump Voters Differ Over Election Security, Vote Counts and Hacking Concerns

Most voters say harris will concede – and trump won’t – if defeated in the election, how voters expect harris’ and trump’s policies to affect different groups in society, in tight u.s. presidential race, latino voters’ preferences mirror 2020, americans in both parties are concerned over the impact of ai on the 2024 presidential campaign, most popular, report materials.

• September 2024 Presidential Preference Detailed Tables
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