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About RIKEN

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RIKEN, a National Research and Development Agency, is Japan's largest comprehensive research institution renowned for high-quality research in a diverse range of scientific disciplines. Founded in 1917, initially as a private research foundation, RIKEN has grown rapidly in size and scope, today encompassing a network of world-class research centers and institutes across Japan.

The pages below offer an overview of RIKEN's mission, its management structure and history, as well as information on RIKEN's campuses and offices, its budget and personnel and its governance. We also have a video in our YouTube channel that introduces the institute .

• October 27, 2021 Professor Motoko Kotani, Executive Vice President for Research at Tohoku University, has been elected as President-Elect of the International Science Council (ISC).

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Overseas Branch Offices

The JST overseas offices are strategically located to capture the latest science and technology trends in their respective regions, actively promote the global activities of JST-funded Japanese researchers and leverage global networks to enhance and internationalize Japan's S&T.

Paris Office

We are JST's first-established overseas office, responsible for a wide range of countries within Europe and Africa. We negotiate and coordinate with relevant organizations and support the growth of JST's European operations, where science cooperation is often multi-layered and complex. We also play a vital role in transmitting local information back to JST headquarters, and are actively expanding our network of related organizations in order to improve Japan's S&T presence in Europe.

Beijing Office

The Beijing office communicates with Chinese government agencies in the coordination of international joint research programs, and supports activities such as the Japan-China University Fair & Forum and "Japan Window" - a website and public social media account providing information about Japan in Chinese language. We cooperate to hold the China-Japan Science and Technology Forum, and work to enhance JST's presence by participating in central and local government events.

Washington D.C. Office

At the Washington, DC Office our mission is to strengthen scientific cooperation between JST and our counterpart organizations, between JST and local scientists and researchers, as well as to study and analyze STI policies and R&D trends in the US. The office has also helped support various scientific collaborative arrangements with other countries in the Americas.

Singapore Office

South and Southeast Asia, home to more than 2 billion people, have achieved remarkable growth in recent years. Located among areas of diverse culture and history, the Singapore office strives to connect Japanese universities, research institutes and companies with these areas for the promotion of JST's operations in Asia. We are actively promoting student exchange program Sakura Science in addition to collaborative research programs offered by JST including e-ASIA, SATREPS, and CHIRP.

India Liaison Office

The India Liaison Office supports JST's Japan-India Collaboration Hubs for International Research Program (CHIRP), the Sakura Science Plan, SATREPS and other international cooperation projects with India. We build scientific networks, expand JST's presence, and investigate local science and technology trends. We are working to become a nexus of exchange between universities, research institutes and companies in Japan and India/South Asia.

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JRI Singapore

Japan Research Institute, Limited is a leading global technology company. The company headquarter is in Tokyo, Japan, including branches/subsidiaries locating in New York, London, and Shanghai.

The Japan Research Institute Limited, Singapore  (JRIS) was established in 1996 and grown to  diverse workforce of over 250 talents. As the APAC headquarter, our business objective is to provide comprehensive and highly value-added information services through the coordinated application of it's 3 functions i.e. information systems, consulting and IT strategic planning. Our commitment to environmental sustainability efforts were recognized, and in the year 2000, we acquired ISO14000 environmental management systems certification. In 2003, The Japan Research Institute became a wholly owned subsidiary of SMBC Group, which owns several different businesses ranging from bank to securities companies.

As a systems integrator, JRI offers services in IT strategic planning, implementation and outsourcing to a broad range of industries and activities to SMBC Group companies.

Our main client is Sumitomo Mitsui Banking Corporation (SMBC), one of the top 3 large mega banks in Japan. JRIS provides comprehensive IT support and functions to their APAC and East Asia branches and subsidiaries.

Our Services

The services provided by JRIS  include;

• IT system planning (for Application, Infrastructure, Security and Operation)
• System development, delivery and project management
• System support and operation
• Support desk service
• Procurement of computers, software and IT related requirement

Our Strategy

Being the IT enabler of SMBC Group, our roles and responsibilities are becoming increasingly important as we play a significant part in the digital transformation journey.  Our vision is to position ourselves as a Technology Company leading the SMBC Group through IT . 

We are committed to achieving this through IT transformation, creating new services and investing in growing a talented workforce.

Copyright© The Japan Research Institute Limited. JRI Singapore is a member of Sumitomo Mitsui Financial Group

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The Japan Economic Research Institute (JERI) was established in 1946, during the chaotic postwar period when Japan’s future was still uncertain. Rather than focusing on the nation’s immediate problems, Kamekichi Takahashi, as JERI’s founder, was determined to study the fundamental questions that concerned the Japanese economy. This has been remained the institute’s objective over the years, as former Chairman Dr. Osamu Shimomura and other researchers have expanded its activities in collaboration with Japan’s economic and academic communities. In the coming years, JERI will continue to devote itself to the betterment of the Japanese economy and the autonomy and sustained development of its regional communities.

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Executive Vice President

Yuri OKINA, Dr.

Chairperson, The Japan Research Institute, Limited

PUBLICATIONS

OPINION PAPER

Is the Ratio of Burden and Benefits Fair for Households Raising Children? - An International Comparative Analysis of Income and Rates of Economic Burden for Employed Households- by Yuri Okina

Toward a Society in Which Establishing a Startup Is a Readily Available Choice by Yutaka Matsuo, Shinichi Takamiya, Shinji Odashima, Komei Fukushima, Florence Neo

Changes in National Debt as a Result of the COVID-19 Pandemic - An International Comparative Perspective - by Yuri Okina

The Feared Acceleration of Decline in Japan's Birthrate Due to COVID-19 by Noriko Tsuya, Fumio Ohtake, Shintaro Yamaguchi, Shiro Yamasaki, Sawako Shirahase

Public Acceptance of an Increase in the Burden of Medical Expenses for the Elderly - Considering the Issues based on the Results of a Deliberative Survey (2)- by Yuri Okina

Characteristics and Issues of Japan's Response to COVID-19 -An International Comparison by Yuri Okina

The Road to Realization of a Carbon-Free Society by Takeo Kikkawa, Hisahide Okuda, Toshihiro Matsumura, Keisuke Sadamori, David Lowe

Why Did Sweden Choose Not to Lock Down?- Constitutional Provisions and National Character Are the Background Factors - by Yuri Okina, Pereric Högberg, Ayako Miyakawa

Responses to COVID-19: Considering the Evidence -How Should We Prepare for a Second Wave? - byMitsuyoshi Urashima, Tai Takahashi, Yuri Okina (Moderator)

Towards a Society in Which Dementia Sufferers Can Live Their Lives as They Wish by Takeshi Iwatsubo, Pereric Högberg, Kohei Komamura, Tomoaki Maekawa, Tadamichi Shimogawara

How Should We Understand the US-China Confrontation? by Satoshi Machidori, Hiroshi Nakanishi, Shin Kawashima, Masahiko Hosokawa, Martin Wolf

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China alone, the covid-19 pandemic complicates japan-china relations: will this benefit asean, modern monetary theory and the case of japan, two worlds collide: common law norms in the service of a national security regime.

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Japan's elderly population living alone to jump 47% by 2050 - research

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Reporting by Kiyoshi Takenaka; Editing by Devika Syamnath

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South Korea's foreign ministry summoned a Japanese diplomat on Tuesday to protest a claim in Japan's annual diplomatic policy Bluebook over a group of islands between the countries at the centre of a longstanding territorial row, Yonhap news reported.

A Kiribati court has ruled that a High Court judge in the Pacific Island nation who has been suspended by the president cannot be deported to Australia where he was born until parliament considers the findings of a tribunal examining a complaint against him.

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China's Xi tells Germany's Scholz to seek 'common ground'

Chinese President Xi Jinping said on Tuesday two-way ties with Germany would continue to develop steadily as long as both respected each other and sought "common ground" while reserving differences.

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Japan to launch new body for future pandemics next April

The health ministry said Tuesday that it will establish a new expert body in April 2025 to prepare for future infectious disease crises.

The government plans to work on details of the body, selecting its leader, who will serve as commander in the event of a pandemic, and deciding the size of its personnel.

"We will tackle future pandemics with a rock-solid system and provide a sense of security to many people in the country," health minister Keizo Takemi said during a preparatory committee meeting.

The new body will integrate the current National Institute of Infectious Diseases and the National Center for Global Health and Medicine.

It will collect and analyze information on infectious diseases, conduct research and development, develop human resources and maintain the medical care system in an integrated manner.

The organization is aimed at expediting initial responses to the emergence of unknown pathogens, such as decisions on the isolation and waiting periods for patients and medical treatment methods.

It will work with the Cabinet Agency for Infectious Disease Crisis Management, launched last September, in the event of an emergency to reflect scientific knowledge in policies.

The body's supervisory department will consist of five divisions including the crisis management bureau, which will carry out information collection and risk assessment on infectious diseases.

The other planned divisions are the general research and development support bureau, the medical services support bureau, the human resources development bureau and the system infrastructure development bureau.

In a time of both misinformation and too much information, quality journalism is more crucial than ever. By subscribing, you can help us get the story right.

Spatial and single-cell colocalisation analysis reveals MDK-mediated immunosuppressive environment with regulatory T cells in colorectal carcinogenesis

Affiliations.

• 1 Department of Surgery, Kyushu University Beppu Hospital, Beppu, 874-0838, Japan; Department of Gastroenterological Surgery, Osaka University Graduate School of Medicine, Suita, 565-0871, Japan.
• 2 Division of Computational Bioscience, National Cancer Center Research Institute, Tokyo, 104-0045, Japan.
• 3 Department of Cancer Biology, Institute of Biomedical Science, Kansai Medical University, Hirakata, 573-1010, Japan. Electronic address: [email protected].
• 4 Department of Surgery, Kyushu University Beppu Hospital, Beppu, 874-0838, Japan.
• 5 Department of Surgery, Kyushu University Beppu Hospital, Beppu, 874-0838, Japan; Department of General Surgical Science, Gastroenterological Surgery, Gunma University Graduate School of Medicine, Maebashi, 371-8511, Japan.
• 6 Department of Gastroenterological Surgery, Osaka University Graduate School of Medicine, Suita, 565-0871, Japan.
• 7 Department of Surgery, Uji-Tokushukai Medical Center, Uji, 611-0041, Japan.
• 8 Department of Gastroenterology, Shin Beppu Hospital, Beppu, 874-8538, Japan.
• 9 Department of Pathology, Kyushu University Beppu Hospital, Beppu, 874-0838, Japan.
• 10 Department of Pathology, Oita Oka Hospital, Oita, 870-0192, Japan.
• 11 Laboratory of Systems Genomics, Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa, 277-8561, Japan.
• 12 Laboratory of Molecular Medicine, Human Genome Center, The Institute of Medical Science, The University of Tokyo, Tokyo, 108-8639, Japan.
• 13 Division of Systems Biology, Nagoya University Graduate School of Medicine, Nagoya, 466-8550, Japan.
• 14 Department of Gastroenterological Medicine, Almeida Memorial Hospital, Oita, 870-1195, Japan.
• 15 Department of Gastroenterology, Oita University Hospital, Yufu, 879-5593, Japan.
• 16 Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, 812-8582, Japan.
• 17 Department of Biochemistry, Nagoya University Graduate School of Medicine, Nagoya, 466-8550, Japan.
• 18 Department of Anatomic Pathology, Kyushu University Hospital, Fukuoka, 812-8582, Japan.
• 19 Tokai University School of Medicine, Isehara, 259-1193, Japan.
• 20 Division of Genetics, Cancer Research Institute, Kanazawa University, Kanazawa, 920-1192, Japan.
• 21 Division of Systems Biology, Nagoya University Graduate School of Medicine, Nagoya, 466-8550, Japan; Department of Computational and Systems Biology, Medical Research Insitute, Tokyo Medical and Dental University, Bunkyo-ku, Tokyo 113-0034, Japan. Electronic address: [email protected].
• 22 Department of Surgery, Kyushu University Beppu Hospital, Beppu, 874-0838, Japan. Electronic address: [email protected].
• PMID: 38614865
• DOI: 10.1016/j.ebiom.2024.105102

Background: Cell-cell interaction factors that facilitate the progression of adenoma to sporadic colorectal cancer (CRC) remain unclear, thereby hindering patient survival.

Methods: We performed spatial transcriptomics on five early CRC cases, which included adenoma and carcinoma, and one advanced CRC. To elucidate cell-cell interactions within the tumour microenvironment (TME), we investigated the colocalisation network at single-cell resolution using a deep generative model for colocalisation analysis, combined with a single-cell transcriptome, and assessed the clinical significance in CRC patients.

Findings: CRC cells colocalised with regulatory T cells (Tregs) at the adenoma-carcinoma interface. At early-stage carcinogenesis, cell-cell interaction inference between colocalised adenoma and cancer epithelial cells and Tregs based on the spatial distribution of single cells highlighted midkine (MDK) as a prominent signalling molecule sent from tumour epithelial cells to Tregs. Interaction between MDK-high CRC cells and SPP1+ macrophages and stromal cells proved to be the mechanism underlying immunosuppression in the TME. Additionally, we identified syndecan4 (SDC4) as a receptor for MDK associated with Treg colocalisation. Finally, clinical analysis using CRC datasets indicated that increased MDK/SDC4 levels correlated with poor overall survival in CRC patients.

Interpretation: MDK is involved in the immune tolerance shown by Tregs to tumour growth. MDK-mediated formation of the TME could be a potential target for early diagnosis and treatment of CRC.

Funding: Japan Society for the Promotion of Science (JSPS) Grant-in-Aid for Science Research; OITA Cancer Research Foundation; AMED under Grant Number; Japan Science and Technology Agency (JST); Takeda Science Foundation; The Princess Takamatsu Cancer Research Fund.

Keywords: Colorectal cancer; Immune tolerance; MDK; SDC4; Single-cell RNA sequencing; Spatial transcriptomics.

Copyright © 2024. Published by Elsevier B.V.

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Japan’s elderly population living alone to jump 47% by 2050 – research

TOKYO (Reuters) – The number of senior citizens living alone in Japan will likely jump 47% by 2050, a government-affiliated research institute said on Friday, underscoring the heavy burden the country’s demographic change will exert on its social security system.

The number of single-person households is expected to reach 23.3 million in 2050, accounting for 44.3% of total households. That would be higher than 38% in 2020, the National Institute of Population and Social Security Research said.

Of those one-person households, senior citizens aged 65 or older will likely represent 46.5% in 2050, compared with 34.9% in 2020, the institute’s estimates showed.

Japan, one of the world’s most advanced ageing societies, has seen a constant decline in the number of marriages in recent decades as a stagnant economy hits the young generations the hardest. The COVID-19 pandemic also came in the way of people meeting their potential partners and tying the knot.

Nearly one-third of Tokyo men in their 50s have never been married, while data gathered by Recruit Holdings shows 46% of men and 30% of women in their 20s in Japan have never dated.

(Reporting by Kiyoshi Takenaka; Editing by Devika Syamnath)

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Home > international_exchange > Technical Cooperation > Joint Seminar, discussion with the government officials（March 2024）

Intellectual support to the Banking and Finance Academy (BFA) (Holding a Joint Seminar and discussion with Related Organizations)

Upon request by the Government of the Republic of Uzbekistan, Policy Research Institute(the PRI) has been providing the Banking and Finance Academy(BFA) with intellectual support for human resource development in Uzbekistan since the BFA’s establishment in 1996. This support has included accepting the BFA students for seminars held in Japan and dispatching the Honorable First Vice-Rector of the BFA (part-time). 　The delegation from the PRI visited Tashkent, Uzbekistan. And the PRI held a joint Seminar with the Ministry of Economy and Finance of The Republic of Uzbekistan(UMOEF) and the BFA, and had a discussion with them regarding the PRI’s future support for Uzbekistan.

[Opening Remarks]

                                   [With Dr. Hoshimov, Rector, BFA]                                           [With Executives, of BFA]

[Discussion with the Ministry of Economy and Finance of The Republic of Uzbekistan]

Japan's machinery orders rise sharply, may ease concerns about domestic demand

By Tetsushi Kajimoto

TOKYO (Reuters) - Japan's key gauge of capital spending jumped the most in a year in February, rebounding sharply from the prior month's decline in a welcome sign for domestic demand even as authorities worry about a weakening yen and its impact on the cost of living.

Core machinery orders rose 7.7% in February from the previous month, blowing past a 0.8% increase expected by economists in a Reuters poll, Cabinet Office data showed on Monday.

It was the fastest growth in core orders since January 2023 and more than recouped a 1.7% fall in the previous month.

"Machinery orders have hit the bottom," said Takeshi Minami, chief economist at Norinchukin Research Institute.

"Japanese firms are making higher profits and hiking wages lately so it's natural for them to raise investment as well," Minami added.

"Still, risks remain due to uncertainty over the global economy. For example, the Middle East crisis may trigger a spike in crude oil prices which would discourage Japanese firms from boosting capex."

Iran launched explosive drones and fired missiles at Israel late on Saturday in its first direct attack on Israeli territory, a retaliatory strike that raised the threat of a wider regional conflict.

Compared with a year earlier, core orders, a highly volatile data series regarded as an indicator of capital spending in the coming six to nine months, declined 1.8% in February but that was again shallower than a 6.0% drop seen by economists.

Brisk capital spending should ease concerns about weak domestic demand as government and central bank policymakers try to stoke a virtuous growth cycle led by durable consumption and solid wages.

Japanese firms have come up with strong plans for investment in plants and equipment in recent years, but uncertainty over the economic outlook has caused delays in implementing those plans.

This time around, however, solid wage hikes offered by major companies should encourage domestic consumption and in turn boost business confidence around capital investment plans, analysts say.

The core orders data was released amid a backdrop of concerns around persistent weakness in the yen.

The Japanese currency slumped to 34-year lows against the dollar beyond 153 yen last week, which could boost import prices and add to already stiff cost-of-living pressures.

Last month, the Bank of Japan ended negative interest rates in a landmark shift away from its decade-long super-easy accommodative policy after major firms offered big pay raise at annual wage talks in mid-March. But monetary conditions are still relatively easy with the BOJ flagging a cautious track for further policy tightening for the rest of this year.

Capital spending is among factors that policymakers will consider as they look to decisively shift Japan onto the path of monetary policy normalisation.

(Reporting by Tetsushi Kajimoto; Editing by Shri Navaratnam)