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- Can J Hosp Pharm
- v.70(4); Jul-Aug 2017
Drug Utilization Research: Methods and Applications
Elseviers M, Wettermark B, Almarsdóttir AB, Andersen M, Benko R, Bennie M, et al., editors. Wiley-Blackwell (Canada), Toronto, Ontario, 2016. ISBN 978-1-118-94978-8. Hardcover, 536 pages. $191.95.
Drug utilization research has evolved over the years to become a cross-disciplinary science that explores the medical, social, and economic consequences of drug utilization. The European Drug Utilization Research Group and the International Society for Pharmacoepidemiology’s Special Interest Group in Drug Utilisation / Health Service Research developed this text to provide a comprehensive introduction and advanced discussion of topics in drug utilization research and pharmacoepidemiology.
The book is organized in 3 parts: Introduction, Methodology, and Applied Drug Utilization Research. The Introduction defines drug utilization research and provides the historical context. The Methodology section begins with basic concepts in study design, data collection, drug measurement units, and ways to graphically represent drug utilization data. This section continues with some advanced statistical methods, covering multilevel analyses and quality indicators and addressing the emerging field of qualitative methods in drug utilization research. The applied research section includes comparative drug utilization research, health policy applications, and research in specific populations (e.g., children, older people) and specific pharmacotherapeutic areas (e.g., infectious diseases, cancer). This section presents the determinants of drug utilization from different perspectives (those of the health system, the prescriber, and the patient), as well as information about adherence research, pharmacoepidemiology, and the assessment and improvement of the quality of medicine use. A brief epilogue provides insights into the future of drug utilization research.
The textbook has several strengths. It spans the entirety of drug utilization research in such detail that the reference should be of value to researchers, academics, and policy-makers. It is a comprehensive resource with information that is easy to access, and would be a useful text for both junior and senior researchers. The reference is not meant to be an all-inclusive source for statistical methods, but the statistics are described in sufficient detail to assist researchers in developing their own drug utilization research projects. A unique feature of this text is the chapter on visualization of drug utilization data, which provides practical hints and tools for displaying data. The editors have taken a global view of drug utilization research; therefore, the book is not dominated by one country or health system. Comparative data across multiple countries are provided to allow a better understanding of other health care systems and their respective drug utilization data. The examples of published research are a notable strength of the textbook; the reader is able to review real examples of drug utilization research to better understand the methodologies described. However, references are not provided in the text; they must be downloaded separately, which is an inconvenience. Colour graphs are not available within individual chapters; instead, the reader is directed to the colour plates section in the middle of the book.
In conclusion, this textbook supports basic drug utilization studies but also provides the experienced researcher with a better understanding of the complexities of designing drug utilization research. Interested individuals, from clinicians to policy-makers, may also use this as a reference for appraisal and application of research findings to improve the quality of medication use at a local and societal level.
Competing interests: None declared.
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ISBN 978-1-118-94978-8. Hardcover, 536 pages. $191.95. Drug utilization research has evolved over the years to become a cross-disciplinary science that explores the medical, social, and economic consequences of drug utilization. The European Drug Utilization Research Group and the International Society for Pharmacoepidemiology's Special ...
Overview. The ultimate goal of drug utilization research must be to assess whether drug therapy is rational or not. History has taught us that successful research in drug utilization requires multidisciplinary collaboration between clinicians, clinical pharmacologists, pharmacists and epidemiologists. Without the support of the prescribers ...
This dissertation is based in two manuscripts. In the first manuscript I actively collaborated in the conception, design, acquisition, analysis and interpretation of data, ... drug utilization, as well as studies of how drug utilization relates to the effects of drug use, beneficial or adverse 2-4. The therapeutic practice is expected to be ...
The study was designed to assess the drug utilization evaluation of anti-diabetic medications through prescription monitoring in a tertiary care hospital at capital city Dehradun in a northern ...
Abstract. This book presents a survey of instruments and methods developed to investigate patterns of drug consumption and to answer fundamental questions about prescribing practices, therapeutic value and safety. By reviewing the state-of-the-art in research methodology, it also aims to show how drug utilization studies can contribute to ...
Drug utilization evaluation (DUE) is defined by the World Health Organization (WHO) and focuses on the medical, social, and economic consequences of pharmaceutical marketing, distribution, prescribing, and usage in society. The WHO recommends a physician to every 1 000 people. According to the recent data from the Health Ministry in 2019, in ...
health care databases (HCDs) 400. health care providers-reported data 30-31. Index 501. health care service delivery 200. health care system drug management. 222-223, 230. demand-side measures 223-225. policy case histories. enhanced generic utilization 227-229.
importance of drug utilization studies in pharmacoepidemiology has been increasing due to their close association to other areas like public health, pharmacovigilance, pharmacoeconomics and pharmacogenetics. In recent years studies on drug utilization have become a potential tool to be used in the evaluation of health systems. Studies on the process of drug utilization focus on factors related ...
Abstract. Drug utilization has recently been defined as follows: "The marketing, distribution, prescription and use of drugs in a society, with special emphasis on the resulting medical, social and economic consequences ". During the last hundred years, the development of more efficient drugs has led to dramatic improvements in health care.
Drug Utilization Research (DUR) is an eclectic scientific discipline, integrating descriptive and analytical methods for the quantification, understanding and evaluation of the processes of prescribing, dispensing and consumption of medicines and for the testing of interventions to enhance the quality of these processes. The discipline is closely related and linked mainly to the broader field ...
Background: While 7 of the top selling drugs in the U.S. have orphan status, 95% of 7000 rare diseases still lack treatments. With the growing number of expensive orphan drugs in the market, insurers have increasingly placed utilization controls (UCs), like prior authorization (PA), on orphan drugs to contain spending.
Objective: This study attempts to get an insight into the utilization pattern of anti-epileptic drugs (AEDs) and their drug interactions in cases collected from the neurology department in a ...
Inappropriate use of drugs can lead to various problems such as cost burden, prolonged hospital stays, development of microbial resistance, adverse effects and mortality[1]. However variations in selection and use of drugs are routinely practiced. Drug utilization studies will be helpful to evaluate and analyse drug therapy from time to time.
Introduction: Drug utilization is the marketing, distribution, prescription and the use of drugs in a society. The method of prescribing antidepressant drugs have changed worldwide in the last couple of years.1 Numerous drugs are seen in this class with different mechanism of action and variable efficacy and safety ...
Drug utilization study of anti-diabetic drugs in a tertiary care hospital Dr. Naseem Begum, Dr. S Ramesh, Dr. B Prahlad and Dr. G Bhawani Abstract Background: Diabetes mellitus is a major non-communicable disease and a risk factor for cardiovascular diseases. The anti-diabetic drugs used for its management constitute a significant portion
The average number of drugs per prescription was 3.73 in male OPD and 3.59 in female OPD. The percentage of generic drugs prescribed was 84.13% in male OPD and 77.3% in female OPD, drugs ...
Keywords: Drug utilization, dermatology, prescriptions 1. Introduction Drug utilization is defined as the marketing, distribution, prescription and use of drugs in a society with special emphasis on the resulting medical and social consequences (WHO 2003) [1]. A study on drug utilization is important for educational, clinical and pharmacoeconomic
Washington Drug Utilization Review (DUR) Board Meeting April 17 th, 2024 Umang Patel, Pharm.D. Agenda Topics 2 Overview of Disease Indications. Dosage & Formulations. Guideline Updates. ... The drug is granted traditional FDA -approval (rather than Accelerated Approval) −(2) Patient is diagnosed with mild cognitive impairment or early ...
Washington State Pharmacy and Therapeutics Committee & Drug Utilization Review Board. Meeting by Zoom Webinar . Wednesday, April 17, 2024, 9 a.m. to 4 p.m. Agenda ... (DUR) Board Convenes (Reviews drug classes for the Apple Health PDL) Kavita Chawla, Committee Chair Apple Health Policy: 62.38.00.AA Movement Disorder Agents: Valbenazine ...