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US halts funding to controversial virus-hunting group: what researchers think

Some scientists think the decision regarding EcoHealth Alliance is fair, while others say it might negatively impact virus surveillance.

• Mariana Lenharo

Found at last: long-lost branch of the Nile that ran by the pyramids

Geological survey reveals the remains of a major waterway that ancient Egyptian builders could have used to transport materials.

• Freda Kreier

Gut microbes linked to fatty diet drive tumour growth

Scientists know there is a link between obesity and some cancers. A study in mice and people suggests why that might be.

• Gillian Dohrn

Imprinting of serum neutralizing antibodies by Wuhan-1 mRNA vaccines

• Chieh-Yu Liang
• Saravanan Raju
• Michael S. Diamond

Publisher Correction: Ghost roads and the destruction of Asia-Pacific tropical forests

• Jayden E. Engert
• Mason J. Campbell
• William F. Laurance

Organoids merge to model the blood–brain barrier

Combining a brain organoid with a blood-vessel organoid yields a system similar to a protective mesh in the brain.

Controlled failure: The building designed to limit catastrophe

New design - inspired by lizard tails - could save lives by isolating collapsing sections of damaged buildings

Evolution of a novel adrenal cell type that promotes parental care

The adrenal gland of the oldfield mouse ( Peromyscus polionotus ) has a recently evolved cell type that promotes monogamous-typical parenting behaviour and is not present in closely related species.

• Natalie Niepoth
• Jennifer R. Merritt
• Andres Bendesky

Suppressed thermal transport in silicon nanoribbons by inhomogeneous strain

We report on a method for inducing uncontaminated and precise inhomogeneous strain in nanoscale silicon ribbons and its use for determining physical effects in these strained materials, in particular, an increase in the range and control of thermal conductivity.

• Shengying Yue

The rise of baobab trees in Madagascar

We carried out genomic and ecological analyses of all eight extant baobab species, providing insights into their evolutionary history and recommendations for conservation efforts.

• Jun-Nan Wan
• Sheng-Wei Wang
• Qing-Feng Wang

Arresting failure propagation in buildings through collapse isolation

A design approach arrests collapse propagation in buildings after major initial failures by ensuring that specific elements fail before the failure of the most important components for global stability.

• Nirvan Makoond
• Andri Setiawan
• Jose M. Adam

Dispersion-assisted high-dimensional photodetector

By combining spatial and frequency dispersive thin-film interfaces with deep residual learning, a miniature photodetector allowing the acquisition of high-dimensional information on light in a single-shot fashion is described.

• Yandong Fan
• Weian Huang

GLP-1-directed NMDA receptor antagonism for obesity treatment

Unimolecular integration of NMDA receptor antagonism with GLP-1 receptor agonism effectively reverses obesity, hyperglycaemia and dyslipidaemia in rodent models of metabolic disease.

• Jonas Petersen
• Mette Q. Ludwig
• Christoffer Clemmensen

Photocatalytic doping of organic semiconductors

A previously undescribed photocatalytic approach enables the effective p-type and n-type doping of organic semiconductors at room temperature using only widely available weak dopants such as oxygen and triethylamine.

• Wenlong Jin
• Chi-Yuan Yang
• Simone Fabiano

The temperature sensor TWA1 is required for thermotolerance in Arabidopsis

TWA1 is a temperature-sensing transcriptional co-regulator that is needed for basal and acquired thermotolerance in Arabidopsis thaliana.

• Erwin Grill

Temporal multiplexing of perception and memory codes in IT cortex

We examined how familiar faces are encoded in inferotemporal, perirhinal and temporal pole face patches, and found that relative response magnitude to familiar versus unfamiliar faces was not a stable indicator of familiarity in any patch.

• Marcus K. Benna
• Doris Y. Tsao

Superconducting diode effect and interference patterns in kagome CsV 3 Sb 5

We observe the superconducting diode effect and interference patterns in CsV 3 Sb 5 , implying a time-reversal symmetry-breaking superconducting order in kagome superconductors.

• Zhiming Pan

Physiological temperature drives TRPM4 ligand recognition and gating

A temperature-dependent Ca 2+ -binding site in the intracellular domain of TRPM4 is essential for TRPM4 function in physiological contexts.

• Sung Jin Park

Entanglement of nanophotonic quantum memory nodes in a telecom network

Entanglement of two nanophotonic quantum network nodes is demonstrated through 40  km spools of low-loss fibre and a 35-km long fibre loop deployed in the Boston area urban environment.

• C. M. Knaut
• A. Suleymanzade
• M. D. Lukin

Engineered CD47 protects T cells for enhanced antitumour immunity

Combination of TCR or CAR T cells expressing the engineered CD47 variant 47 E with anti-CD47 antibody therapy results in synergistic antitumour efficacy due to T cell resistance to clearance by macrophages, while maintaining macrophage recruitment into the tumour microenvironment.

• Sean A. Yamada-Hunter
• Johanna Theruvath
• Crystal L. Mackall

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