chronic kidney failure research papers

Chronic kidney disease (CKD) affects between 8% and 16% of the population worldwide and is often underrecognized by patients and clinicians. 1-4 Defined by a glomerular filtration rate (GFR) of less than 60 mL/min/1.73 m 2, albuminuria of at least 30 mg per 24 hours, or markers of kidney damage (eg, hematuria or structural abnormalities such as polycystic or dysplastic kidneys) persisting ...

Chronic kidney disease (CKD) refers to a condition affecting the kidneys, with a gradual decline in kidney function that occurs over several months to several years. This disorder is common (about ...

Chronic kidney disease is a progressive disease with no cure and high morbidity and mortality that occurs commonly in the general adult population, especially in people with diabetes and hypertension. Preservation of kidney function can improve outcomes and can be achieved through non-pharmacological strategies (eg, dietary and lifestyle adjustments) and chronic kidney disease-targeted and ...

N.R. PoweN Engl J Med 2023;388:1043-1044. Chronic kidney disease (CKD) is a public health problem worldwide. In the United States, for the past four decades, CKD in its most severe form, end-stage ...

Chronic kidney disease (CKD) is a non-communicable disease that includes a range of different physiological disorders that are associated with abnormal renal function and progressive decline in glomerular filtration rate (GFR). ... This paper is part of a thesis conducted by Mousa Ghelichi-Ghojogh, Ph.D. student of epidemiology, and a research ...

Chronic kidney disease is a progressive disease with no cure and high morbidity and mortality that occurs commonly in the general adult population, especially in people with diabetes and hypertension. Preservation of kidney function can improve outcomes and can be achieved through non-pharmacological strategies (eg, dietary and lifestyle ...

Chronic kidney disease is a life-changing diagnosis for millions of people worldwide, as the risk of disease progression and kidney failure creates unbearable uncertainty and limits lifestyle ...

Overview of Pediatric Nephrology for Adult Nephrologists. Edited by Rupesh Raina MD, Sidharth Sethi MD. May 2022. View all special issues and article collections. View all issues. Read the latest articles of Advances in Chronic Kidney Disease at ScienceDirect.com, Elsevier's leading platform of peer-reviewed scholarly literature.

Publication of the Kidney Disease Outcomes Quality Initiative (KDOQI) definition and classification system for chronic kidney disease (CKD) in 2002 (ref. 1) spurred the development of prevention ...

Abstract. Importance: Chronic kidney disease (CKD) is the 16th leading cause of years of life lost worldwide. Appropriate screening, diagnosis, and management by primary care clinicians are necessary to prevent adverse CKD-associated outcomes, including cardiovascular disease, end-stage kidney disease, and death.

Chronic kidney disease: highlights from research. Illuminating genetic risk, disrupting fibrosis and intercepting inflammation. A kidney organoid containing nephron epithelial cells and stromal ...

ImportanceChronic kidney disease (CKD) is the 16th leading cause of years of life lost worldwide. Appropriate screening, diagnosis, and management by primary care clinicians are necessary to prevent adverse CKD-associated outcomes, including cardiovascular disease, end-stage kidney disease, and death. ObservationsDefined as a persistent ...

8 Amsterdam Public Health Research Institute, Quality of Care, Amsterdam, the Netherlands. [email protected]. PMID: ... Women have a higher prevalence of chronic kidney disease (CKD) stages 3-5 than men, whereas men have a higher prevalence of albuminuria and hence CKD stages 1-2. Men show a faster decline in kidney function, progress ...

Chronic Kidney Disease (CKD) is a state of progressive loss of kidney function ultimately resulting in the need for renal replacement therapy (dialysis or transplantation) [].It is defined as the presence of kidney damage or an estimated glomerular filtration rate less than 60 ml/min per 1.73 m 2, persisting for 3 months or more [].CKD prevalence is growing worldwide, along with demographic ...

In Japan, the Japanese Society of Nephrology published the "Clinical Practice Guidebook for Diagnosis and Treatment of Chronic Kidney Disease" in 2007 as a tool for deepening collaboration between primary care physicians and nephrologists as well as facilitating collaboration between hospitals and clinics, which was revised in 2009 and 2012.

Chronic kidney disease (CKD) is a common condition associated with significant amenable morbidity and mortality, primarily related to the substantially increased risk of cardiovascular disease (CVD) in this population. Early detection of people with CKD is important so that treatment can be initiated to prevent or delay kidney disease progression, reduce or prevent the development of ...

Norberto Perico, Giuseppe Remuzzi, Chronic kidney disease: a research and public health priority, Nephrology Dialysis Transplantation, Volume 27, Issue suppl_3, October 2012, ... Chronic kidney disease (CKD) is a key determinant of the poor health outcomes for major NCDs . CKD is a worldwide threat to public health, but the size of the problem ...

Prior research has established associations between immune cells, inflammatory proteins, and chronic kidney disease (CKD). Our Mendelian randomization study aims to elucidate the genetic causal relationships among these factors and CKD. We applied Mendelian randomization using genetic variants associated with CKD from a large genome-wide association study (GWAS) and inflammatory markers from a ...

The kidney is among the most metabolically active organs, with very high oxygen demand and the second-highest mitochondrial density after the myocardium.27 While oxidative metabolism is the principal source of energy in the kidney, the fuel substrates for metabolism differ across regions of the kidney. In the healthy kidney, both fatty acid oxidation (FAO) in the proximal tubules and ...

Heart failure (HF) is an important cause of morbidity and mortality among individuals with chronic kidney disease (CKD). A large body of evidence from preclinical and clinical studies implicates excess levels of fibroblast growth factor 23 (FGF23) in HF pathogenesis in CKD. It remains unclear whether the relationship between elevated FGF23 levels and HF risk…

Chronic kidney disease (CKD) is a significant healthcare burden that affects billions of individuals worldwide 1,2 and makes a profound impact on global morbidity and mortality 3,4,5.In the United ...

Chronic kidney disease (CKD) is typically defined by a glomerular filtration rate of less than 60 ml/min/1.73 m2 or the presence of other indicators of kidney damage, such as albuminuria [1, 2].CKD represents a global public health challenge, impacting about 10-14% of the adult population worldwide [3, 4].Moreover, CKD is closely linked to the increased prevalence of conditions such as ...

PKD progression can be exacerbated by the presence of renal innate immune cells [11]. This interesting aspect is examined in the review by Agborbesong et al., focusing on epigenetic regulation, inflammation, and cell death as molecular mechanisms underlying ADPKD. It draws attention to the intricate interplay that drives cyst formation and disease progression, involving PKD gene alterations ...

@article{Winarti2024TheRB, title={The Relationship between Long Time Undergoing Hemodialysis and Stress Levels in Chronic Kidney Failure Patients Undergoing Hemodialysis at Bendan Regional Hospital, Pekalongan City}, author={Rahayu Winarti and Wahyu Hidayat and Chandra Hadi Prasetya}, journal={Global International Journal of Innovative Research ...

"In earlier research, we found that conservative weight-loss approaches do not adequately result in significant weight loss in patients with advanced chronic kidney disease," says Aleksandra Kukla ...