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7.3 Quasi-Experimental Research

Learning objectives.

  • Explain what quasi-experimental research is and distinguish it clearly from both experimental and correlational research.
  • Describe three different types of quasi-experimental research designs (nonequivalent groups, pretest-posttest, and interrupted time series) and identify examples of each one.

The prefix quasi means “resembling.” Thus quasi-experimental research is research that resembles experimental research but is not true experimental research. Although the independent variable is manipulated, participants are not randomly assigned to conditions or orders of conditions (Cook & Campbell, 1979). Because the independent variable is manipulated before the dependent variable is measured, quasi-experimental research eliminates the directionality problem. But because participants are not randomly assigned—making it likely that there are other differences between conditions—quasi-experimental research does not eliminate the problem of confounding variables. In terms of internal validity, therefore, quasi-experiments are generally somewhere between correlational studies and true experiments.

Quasi-experiments are most likely to be conducted in field settings in which random assignment is difficult or impossible. They are often conducted to evaluate the effectiveness of a treatment—perhaps a type of psychotherapy or an educational intervention. There are many different kinds of quasi-experiments, but we will discuss just a few of the most common ones here.

Nonequivalent Groups Design

Recall that when participants in a between-subjects experiment are randomly assigned to conditions, the resulting groups are likely to be quite similar. In fact, researchers consider them to be equivalent. When participants are not randomly assigned to conditions, however, the resulting groups are likely to be dissimilar in some ways. For this reason, researchers consider them to be nonequivalent. A nonequivalent groups design , then, is a between-subjects design in which participants have not been randomly assigned to conditions.

Imagine, for example, a researcher who wants to evaluate a new method of teaching fractions to third graders. One way would be to conduct a study with a treatment group consisting of one class of third-grade students and a control group consisting of another class of third-grade students. This would be a nonequivalent groups design because the students are not randomly assigned to classes by the researcher, which means there could be important differences between them. For example, the parents of higher achieving or more motivated students might have been more likely to request that their children be assigned to Ms. Williams’s class. Or the principal might have assigned the “troublemakers” to Mr. Jones’s class because he is a stronger disciplinarian. Of course, the teachers’ styles, and even the classroom environments, might be very different and might cause different levels of achievement or motivation among the students. If at the end of the study there was a difference in the two classes’ knowledge of fractions, it might have been caused by the difference between the teaching methods—but it might have been caused by any of these confounding variables.

Of course, researchers using a nonequivalent groups design can take steps to ensure that their groups are as similar as possible. In the present example, the researcher could try to select two classes at the same school, where the students in the two classes have similar scores on a standardized math test and the teachers are the same sex, are close in age, and have similar teaching styles. Taking such steps would increase the internal validity of the study because it would eliminate some of the most important confounding variables. But without true random assignment of the students to conditions, there remains the possibility of other important confounding variables that the researcher was not able to control.

Pretest-Posttest Design

In a pretest-posttest design , the dependent variable is measured once before the treatment is implemented and once after it is implemented. Imagine, for example, a researcher who is interested in the effectiveness of an antidrug education program on elementary school students’ attitudes toward illegal drugs. The researcher could measure the attitudes of students at a particular elementary school during one week, implement the antidrug program during the next week, and finally, measure their attitudes again the following week. The pretest-posttest design is much like a within-subjects experiment in which each participant is tested first under the control condition and then under the treatment condition. It is unlike a within-subjects experiment, however, in that the order of conditions is not counterbalanced because it typically is not possible for a participant to be tested in the treatment condition first and then in an “untreated” control condition.

If the average posttest score is better than the average pretest score, then it makes sense to conclude that the treatment might be responsible for the improvement. Unfortunately, one often cannot conclude this with a high degree of certainty because there may be other explanations for why the posttest scores are better. One category of alternative explanations goes under the name of history . Other things might have happened between the pretest and the posttest. Perhaps an antidrug program aired on television and many of the students watched it, or perhaps a celebrity died of a drug overdose and many of the students heard about it. Another category of alternative explanations goes under the name of maturation . Participants might have changed between the pretest and the posttest in ways that they were going to anyway because they are growing and learning. If it were a yearlong program, participants might become less impulsive or better reasoners and this might be responsible for the change.

Another alternative explanation for a change in the dependent variable in a pretest-posttest design is regression to the mean . This refers to the statistical fact that an individual who scores extremely on a variable on one occasion will tend to score less extremely on the next occasion. For example, a bowler with a long-term average of 150 who suddenly bowls a 220 will almost certainly score lower in the next game. Her score will “regress” toward her mean score of 150. Regression to the mean can be a problem when participants are selected for further study because of their extreme scores. Imagine, for example, that only students who scored especially low on a test of fractions are given a special training program and then retested. Regression to the mean all but guarantees that their scores will be higher even if the training program has no effect. A closely related concept—and an extremely important one in psychological research—is spontaneous remission . This is the tendency for many medical and psychological problems to improve over time without any form of treatment. The common cold is a good example. If one were to measure symptom severity in 100 common cold sufferers today, give them a bowl of chicken soup every day, and then measure their symptom severity again in a week, they would probably be much improved. This does not mean that the chicken soup was responsible for the improvement, however, because they would have been much improved without any treatment at all. The same is true of many psychological problems. A group of severely depressed people today is likely to be less depressed on average in 6 months. In reviewing the results of several studies of treatments for depression, researchers Michael Posternak and Ivan Miller found that participants in waitlist control conditions improved an average of 10 to 15% before they received any treatment at all (Posternak & Miller, 2001). Thus one must generally be very cautious about inferring causality from pretest-posttest designs.

Does Psychotherapy Work?

Early studies on the effectiveness of psychotherapy tended to use pretest-posttest designs. In a classic 1952 article, researcher Hans Eysenck summarized the results of 24 such studies showing that about two thirds of patients improved between the pretest and the posttest (Eysenck, 1952). But Eysenck also compared these results with archival data from state hospital and insurance company records showing that similar patients recovered at about the same rate without receiving psychotherapy. This suggested to Eysenck that the improvement that patients showed in the pretest-posttest studies might be no more than spontaneous remission. Note that Eysenck did not conclude that psychotherapy was ineffective. He merely concluded that there was no evidence that it was, and he wrote of “the necessity of properly planned and executed experimental studies into this important field” (p. 323). You can read the entire article here:

http://psychclassics.yorku.ca/Eysenck/psychotherapy.htm

Fortunately, many other researchers took up Eysenck’s challenge, and by 1980 hundreds of experiments had been conducted in which participants were randomly assigned to treatment and control conditions, and the results were summarized in a classic book by Mary Lee Smith, Gene Glass, and Thomas Miller (Smith, Glass, & Miller, 1980). They found that overall psychotherapy was quite effective, with about 80% of treatment participants improving more than the average control participant. Subsequent research has focused more on the conditions under which different types of psychotherapy are more or less effective.

Han Eysenck

In a classic 1952 article, researcher Hans Eysenck pointed out the shortcomings of the simple pretest-posttest design for evaluating the effectiveness of psychotherapy.

Wikimedia Commons – CC BY-SA 3.0.

Interrupted Time Series Design

A variant of the pretest-posttest design is the interrupted time-series design . A time series is a set of measurements taken at intervals over a period of time. For example, a manufacturing company might measure its workers’ productivity each week for a year. In an interrupted time series-design, a time series like this is “interrupted” by a treatment. In one classic example, the treatment was the reduction of the work shifts in a factory from 10 hours to 8 hours (Cook & Campbell, 1979). Because productivity increased rather quickly after the shortening of the work shifts, and because it remained elevated for many months afterward, the researcher concluded that the shortening of the shifts caused the increase in productivity. Notice that the interrupted time-series design is like a pretest-posttest design in that it includes measurements of the dependent variable both before and after the treatment. It is unlike the pretest-posttest design, however, in that it includes multiple pretest and posttest measurements.

Figure 7.5 “A Hypothetical Interrupted Time-Series Design” shows data from a hypothetical interrupted time-series study. The dependent variable is the number of student absences per week in a research methods course. The treatment is that the instructor begins publicly taking attendance each day so that students know that the instructor is aware of who is present and who is absent. The top panel of Figure 7.5 “A Hypothetical Interrupted Time-Series Design” shows how the data might look if this treatment worked. There is a consistently high number of absences before the treatment, and there is an immediate and sustained drop in absences after the treatment. The bottom panel of Figure 7.5 “A Hypothetical Interrupted Time-Series Design” shows how the data might look if this treatment did not work. On average, the number of absences after the treatment is about the same as the number before. This figure also illustrates an advantage of the interrupted time-series design over a simpler pretest-posttest design. If there had been only one measurement of absences before the treatment at Week 7 and one afterward at Week 8, then it would have looked as though the treatment were responsible for the reduction. The multiple measurements both before and after the treatment suggest that the reduction between Weeks 7 and 8 is nothing more than normal week-to-week variation.

Figure 7.5 A Hypothetical Interrupted Time-Series Design

A Hypothetical Interrupted Time-Series Design - The top panel shows data that suggest that the treatment caused a reduction in absences. The bottom panel shows data that suggest that it did not

The top panel shows data that suggest that the treatment caused a reduction in absences. The bottom panel shows data that suggest that it did not.

Combination Designs

A type of quasi-experimental design that is generally better than either the nonequivalent groups design or the pretest-posttest design is one that combines elements of both. There is a treatment group that is given a pretest, receives a treatment, and then is given a posttest. But at the same time there is a control group that is given a pretest, does not receive the treatment, and then is given a posttest. The question, then, is not simply whether participants who receive the treatment improve but whether they improve more than participants who do not receive the treatment.

Imagine, for example, that students in one school are given a pretest on their attitudes toward drugs, then are exposed to an antidrug program, and finally are given a posttest. Students in a similar school are given the pretest, not exposed to an antidrug program, and finally are given a posttest. Again, if students in the treatment condition become more negative toward drugs, this could be an effect of the treatment, but it could also be a matter of history or maturation. If it really is an effect of the treatment, then students in the treatment condition should become more negative than students in the control condition. But if it is a matter of history (e.g., news of a celebrity drug overdose) or maturation (e.g., improved reasoning), then students in the two conditions would be likely to show similar amounts of change. This type of design does not completely eliminate the possibility of confounding variables, however. Something could occur at one of the schools but not the other (e.g., a student drug overdose), so students at the first school would be affected by it while students at the other school would not.

Finally, if participants in this kind of design are randomly assigned to conditions, it becomes a true experiment rather than a quasi experiment. In fact, it is the kind of experiment that Eysenck called for—and that has now been conducted many times—to demonstrate the effectiveness of psychotherapy.

Key Takeaways

  • Quasi-experimental research involves the manipulation of an independent variable without the random assignment of participants to conditions or orders of conditions. Among the important types are nonequivalent groups designs, pretest-posttest, and interrupted time-series designs.
  • Quasi-experimental research eliminates the directionality problem because it involves the manipulation of the independent variable. It does not eliminate the problem of confounding variables, however, because it does not involve random assignment to conditions. For these reasons, quasi-experimental research is generally higher in internal validity than correlational studies but lower than true experiments.
  • Practice: Imagine that two college professors decide to test the effect of giving daily quizzes on student performance in a statistics course. They decide that Professor A will give quizzes but Professor B will not. They will then compare the performance of students in their two sections on a common final exam. List five other variables that might differ between the two sections that could affect the results.

Discussion: Imagine that a group of obese children is recruited for a study in which their weight is measured, then they participate for 3 months in a program that encourages them to be more active, and finally their weight is measured again. Explain how each of the following might affect the results:

  • regression to the mean
  • spontaneous remission

Cook, T. D., & Campbell, D. T. (1979). Quasi-experimentation: Design & analysis issues in field settings . Boston, MA: Houghton Mifflin.

Eysenck, H. J. (1952). The effects of psychotherapy: An evaluation. Journal of Consulting Psychology, 16 , 319–324.

Posternak, M. A., & Miller, I. (2001). Untreated short-term course of major depression: A meta-analysis of studies using outcomes from studies using wait-list control groups. Journal of Affective Disorders, 66 , 139–146.

Smith, M. L., Glass, G. V., & Miller, T. I. (1980). The benefits of psychotherapy . Baltimore, MD: Johns Hopkins University Press.

Research Methods in Psychology Copyright © 2016 by University of Minnesota is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License , except where otherwise noted.

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Bell, S. H. (2010). The urban institute research of record: Quasi-experimental methods. Washington, DC: The Urban Institute. Retrieved Nov. 20, 2010, from http://www.urban.org/toolkit/data-methods/quasi-experimental.cfm

Campbell, D. T., & Stanley, J. C. (1966). Experimental and quasi-experimental designs for research . Chicago: Rand McNally.

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Shadish, W. R., Cook, T. D., & Campbell, T. D. (2002). Experimental and quasi-experimental designs for generalized causal inference . Boston: Houghton-Mifflin.

Trochim, W. M. (2006). The research methods knowledge base (2nd ed.). Cincinnati: Atomic Dog. Retrieved Nov. 20, 2011, from http://www.socialresearchmethods.net/kb/

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Quasi-Experiment: Understand What It Is, Types & Examples

Discover the concept of quasi-experiment, its various types, real-world examples, and how QuestionPro aids in conducting these studies.

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Quasi-experimental research designs have gained significant recognition in the scientific community due to their unique ability to study cause-and-effect relationships in real-world settings. Unlike true experiments, quasi-experiment lack random assignment of participants to groups, making them more practical and ethical in certain situations. In this article, we will delve into the concept, applications, and advantages of quasi-experiments, shedding light on their relevance and significance in the scientific realm.

What Is A Quasi-Experiment Research Design?

Quasi-experimental research designs are research methodologies that resemble true experiments but lack the randomized assignment of participants to groups. In a true experiment, researchers randomly assign participants to either an experimental group or a control group, allowing for a comparison of the effects of an independent variable on the dependent variable. However, in quasi-experiments, this random assignment is often not possible or ethically permissible, leading to the adoption of alternative strategies.

Types Of Quasi-Experimental Designs

There are several types of quasi-experiment designs to study causal relationships in specific contexts. Some common types include:

Non-Equivalent Groups Design

This design involves selecting pre-existing groups that differ in some key characteristics and comparing their responses to the independent variable. Although the researcher does not randomly assign the groups, they can still examine the effects of the independent variable.

Regression Discontinuity

This design utilizes a cutoff point or threshold to determine which participants receive the treatment or intervention. It assumes that participants on either side of the cutoff are similar in all other aspects, except for their exposure to the independent variable.

Interrupted Time Series Design

This design involves measuring the dependent variable multiple times before and after the introduction of an intervention or treatment. By comparing the trends in the dependent variable, researchers can infer the impact of the intervention.

Natural Experiments

Natural experiments take advantage of naturally occurring events or circumstances that mimic the random assignment found in true experiments. Participants are exposed to different conditions in situations identified by researchers without any manipulation from them.

Application of the Quasi-Experiment Design

Quasi-experimental research designs find applications in various fields, ranging from education to public health and beyond. One significant advantage of quasi-experiments is their feasibility in real-world settings where randomization is not always possible or ethical.

Ethical Reasons

Ethical concerns often arise in research when randomizing participants to different groups could potentially deny individuals access to beneficial treatments or interventions. In such cases, quasi-experimental designs provide an ethical alternative, allowing researchers to study the impact of interventions without depriving anyone of potential benefits.

Examples Of Quasi-Experimental Design

Let’s explore a few examples of quasi-experimental designs to understand their application in different contexts.

Design Of Non-Equivalent Groups

Determining the effectiveness of math apps in supplementing math classes.

Imagine a study aiming to determine the effectiveness of math apps in supplementing traditional math classes in a school. Randomly assigning students to different groups might be impractical or disrupt the existing classroom structure. Instead, researchers can select two comparable classes, one receiving the math app intervention and the other continuing with traditional teaching methods. By comparing the performance of the two groups, researchers can draw conclusions about the app’s effectiveness.

To conduct a quasi-experiment study like the one mentioned above, researchers can utilize QuestionPro , an advanced research platform that offers comprehensive survey and data analysis tools. With QuestionPro, researchers can design surveys to collect data, analyze results, and gain valuable insights for their quasi-experimental research.

How QuestionPro Helps In Quasi-Experimental Research?

QuestionPro’s powerful features, such as random assignment of participants, survey branching, and data visualization, enable researchers to efficiently conduct and analyze quasi-experimental studies. The platform provides a user-friendly interface and robust reporting capabilities, empowering researchers to gather data, explore relationships, and draw meaningful conclusions.

In some cases, researchers can leverage natural experiments to examine causal relationships. 

Determining The Effectiveness Of Teaching Modern Leadership Techniques In Start-Up Businesses

Consider a study evaluating the effectiveness of teaching modern leadership techniques in start-up businesses. Instead of artificially assigning businesses to different groups, researchers can observe those that naturally adopt modern leadership techniques and compare their outcomes to those of businesses that have not implemented such practices.

Advantages and Disadvantages Of The Quasi-Experimental Design

Quasi-experimental designs offer several advantages over true experiments, making them valuable tools in research:

  • Scope of the research : Quasi-experiments allow researchers to study cause-and-effect relationships in real-world settings, providing valuable insights into complex phenomena that may be challenging to replicate in a controlled laboratory environment.
  • Regression Discontinuity : Researchers can utilize regression discontinuity to evaluate the effects of interventions or treatments when random assignment is not feasible. This design leverages existing data and naturally occurring thresholds to draw causal inferences.

Disadvantage

Lack of random assignment : Quasi-experimental designs lack the random assignment of participants, which introduces the possibility of confounding variables affecting the results. Researchers must carefully consider potential alternative explanations for observed effects.

What Are The Different Quasi-Experimental Study Designs?

Quasi-experimental designs encompass various approaches, including nonequivalent group designs, interrupted time series designs, and natural experiments. Each design offers unique advantages and limitations, providing researchers with versatile tools to explore causal relationships in different contexts.

Example Of The Natural Experiment Approach

Researchers interested in studying the impact of a public health campaign aimed at reducing smoking rates may take advantage of a natural experiment. By comparing smoking rates in a region that has implemented the campaign to a similar region that has not, researchers can examine the effectiveness of the intervention.

Differences Between Quasi-Experiments And True Experiments

Quasi-experiments and true experiments differ primarily in their ability to randomly assign participants to groups. While true experiments provide a higher level of control, quasi-experiments offer practical and ethical alternatives in situations where randomization is not feasible or desirable.

Example Comparing A True Experiment And Quasi-Experiment

In a true experiment investigating the effects of a new medication on a specific condition, researchers would randomly assign participants to either the experimental group, which receives the medication, or the control group, which receives a placebo. In a quasi-experiment, researchers might instead compare patients who voluntarily choose to take the medication to those who do not, examining the differences in outcomes between the two groups.

Quasi-Experiment: A Quick Wrap-Up

Quasi-experimental research designs play a vital role in scientific inquiry by allowing researchers to investigate cause-and-effect relationships in real-world settings. These designs offer practical and ethical alternatives to true experiments, making them valuable tools in various fields of study. With their versatility and applicability, quasi-experimental designs continue to contribute to our understanding of complex phenomena.

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Research Method

Home » Quasi-Experimental Research Design – Types, Methods

Quasi-Experimental Research Design – Types, Methods

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Quasi-Experimental Design

Quasi-Experimental Design

Quasi-experimental design is a research method that seeks to evaluate the causal relationships between variables, but without the full control over the independent variable(s) that is available in a true experimental design.

In a quasi-experimental design, the researcher uses an existing group of participants that is not randomly assigned to the experimental and control groups. Instead, the groups are selected based on pre-existing characteristics or conditions, such as age, gender, or the presence of a certain medical condition.

Types of Quasi-Experimental Design

There are several types of quasi-experimental designs that researchers use to study causal relationships between variables. Here are some of the most common types:

Non-Equivalent Control Group Design

This design involves selecting two groups of participants that are similar in every way except for the independent variable(s) that the researcher is testing. One group receives the treatment or intervention being studied, while the other group does not. The two groups are then compared to see if there are any significant differences in the outcomes.

Interrupted Time-Series Design

This design involves collecting data on the dependent variable(s) over a period of time, both before and after an intervention or event. The researcher can then determine whether there was a significant change in the dependent variable(s) following the intervention or event.

Pretest-Posttest Design

This design involves measuring the dependent variable(s) before and after an intervention or event, but without a control group. This design can be useful for determining whether the intervention or event had an effect, but it does not allow for control over other factors that may have influenced the outcomes.

Regression Discontinuity Design

This design involves selecting participants based on a specific cutoff point on a continuous variable, such as a test score. Participants on either side of the cutoff point are then compared to determine whether the intervention or event had an effect.

Natural Experiments

This design involves studying the effects of an intervention or event that occurs naturally, without the researcher’s intervention. For example, a researcher might study the effects of a new law or policy that affects certain groups of people. This design is useful when true experiments are not feasible or ethical.

Data Analysis Methods

Here are some data analysis methods that are commonly used in quasi-experimental designs:

Descriptive Statistics

This method involves summarizing the data collected during a study using measures such as mean, median, mode, range, and standard deviation. Descriptive statistics can help researchers identify trends or patterns in the data, and can also be useful for identifying outliers or anomalies.

Inferential Statistics

This method involves using statistical tests to determine whether the results of a study are statistically significant. Inferential statistics can help researchers make generalizations about a population based on the sample data collected during the study. Common statistical tests used in quasi-experimental designs include t-tests, ANOVA, and regression analysis.

Propensity Score Matching

This method is used to reduce bias in quasi-experimental designs by matching participants in the intervention group with participants in the control group who have similar characteristics. This can help to reduce the impact of confounding variables that may affect the study’s results.

Difference-in-differences Analysis

This method is used to compare the difference in outcomes between two groups over time. Researchers can use this method to determine whether a particular intervention has had an impact on the target population over time.

Interrupted Time Series Analysis

This method is used to examine the impact of an intervention or treatment over time by comparing data collected before and after the intervention or treatment. This method can help researchers determine whether an intervention had a significant impact on the target population.

Regression Discontinuity Analysis

This method is used to compare the outcomes of participants who fall on either side of a predetermined cutoff point. This method can help researchers determine whether an intervention had a significant impact on the target population.

Steps in Quasi-Experimental Design

Here are the general steps involved in conducting a quasi-experimental design:

  • Identify the research question: Determine the research question and the variables that will be investigated.
  • Choose the design: Choose the appropriate quasi-experimental design to address the research question. Examples include the pretest-posttest design, non-equivalent control group design, regression discontinuity design, and interrupted time series design.
  • Select the participants: Select the participants who will be included in the study. Participants should be selected based on specific criteria relevant to the research question.
  • Measure the variables: Measure the variables that are relevant to the research question. This may involve using surveys, questionnaires, tests, or other measures.
  • Implement the intervention or treatment: Implement the intervention or treatment to the participants in the intervention group. This may involve training, education, counseling, or other interventions.
  • Collect data: Collect data on the dependent variable(s) before and after the intervention. Data collection may also include collecting data on other variables that may impact the dependent variable(s).
  • Analyze the data: Analyze the data collected to determine whether the intervention had a significant impact on the dependent variable(s).
  • Draw conclusions: Draw conclusions about the relationship between the independent and dependent variables. If the results suggest a causal relationship, then appropriate recommendations may be made based on the findings.

Quasi-Experimental Design Examples

Here are some examples of real-time quasi-experimental designs:

  • Evaluating the impact of a new teaching method: In this study, a group of students are taught using a new teaching method, while another group is taught using the traditional method. The test scores of both groups are compared before and after the intervention to determine whether the new teaching method had a significant impact on student performance.
  • Assessing the effectiveness of a public health campaign: In this study, a public health campaign is launched to promote healthy eating habits among a targeted population. The behavior of the population is compared before and after the campaign to determine whether the intervention had a significant impact on the target behavior.
  • Examining the impact of a new medication: In this study, a group of patients is given a new medication, while another group is given a placebo. The outcomes of both groups are compared to determine whether the new medication had a significant impact on the targeted health condition.
  • Evaluating the effectiveness of a job training program : In this study, a group of unemployed individuals is enrolled in a job training program, while another group is not enrolled in any program. The employment rates of both groups are compared before and after the intervention to determine whether the training program had a significant impact on the employment rates of the participants.
  • Assessing the impact of a new policy : In this study, a new policy is implemented in a particular area, while another area does not have the new policy. The outcomes of both areas are compared before and after the intervention to determine whether the new policy had a significant impact on the targeted behavior or outcome.

Applications of Quasi-Experimental Design

Here are some applications of quasi-experimental design:

  • Educational research: Quasi-experimental designs are used to evaluate the effectiveness of educational interventions, such as new teaching methods, technology-based learning, or educational policies.
  • Health research: Quasi-experimental designs are used to evaluate the effectiveness of health interventions, such as new medications, public health campaigns, or health policies.
  • Social science research: Quasi-experimental designs are used to investigate the impact of social interventions, such as job training programs, welfare policies, or criminal justice programs.
  • Business research: Quasi-experimental designs are used to evaluate the impact of business interventions, such as marketing campaigns, new products, or pricing strategies.
  • Environmental research: Quasi-experimental designs are used to evaluate the impact of environmental interventions, such as conservation programs, pollution control policies, or renewable energy initiatives.

When to use Quasi-Experimental Design

Here are some situations where quasi-experimental designs may be appropriate:

  • When the research question involves investigating the effectiveness of an intervention, policy, or program : In situations where it is not feasible or ethical to randomly assign participants to intervention and control groups, quasi-experimental designs can be used to evaluate the impact of the intervention on the targeted outcome.
  • When the sample size is small: In situations where the sample size is small, it may be difficult to randomly assign participants to intervention and control groups. Quasi-experimental designs can be used to investigate the impact of an intervention without requiring a large sample size.
  • When the research question involves investigating a naturally occurring event : In some situations, researchers may be interested in investigating the impact of a naturally occurring event, such as a natural disaster or a major policy change. Quasi-experimental designs can be used to evaluate the impact of the event on the targeted outcome.
  • When the research question involves investigating a long-term intervention: In situations where the intervention or program is long-term, it may be difficult to randomly assign participants to intervention and control groups for the entire duration of the intervention. Quasi-experimental designs can be used to evaluate the impact of the intervention over time.
  • When the research question involves investigating the impact of a variable that cannot be manipulated : In some situations, it may not be possible or ethical to manipulate a variable of interest. Quasi-experimental designs can be used to investigate the relationship between the variable and the targeted outcome.

Purpose of Quasi-Experimental Design

The purpose of quasi-experimental design is to investigate the causal relationship between two or more variables when it is not feasible or ethical to conduct a randomized controlled trial (RCT). Quasi-experimental designs attempt to emulate the randomized control trial by mimicking the control group and the intervention group as much as possible.

The key purpose of quasi-experimental design is to evaluate the impact of an intervention, policy, or program on a targeted outcome while controlling for potential confounding factors that may affect the outcome. Quasi-experimental designs aim to answer questions such as: Did the intervention cause the change in the outcome? Would the outcome have changed without the intervention? And was the intervention effective in achieving its intended goals?

Quasi-experimental designs are useful in situations where randomized controlled trials are not feasible or ethical. They provide researchers with an alternative method to evaluate the effectiveness of interventions, policies, and programs in real-life settings. Quasi-experimental designs can also help inform policy and practice by providing valuable insights into the causal relationships between variables.

Overall, the purpose of quasi-experimental design is to provide a rigorous method for evaluating the impact of interventions, policies, and programs while controlling for potential confounding factors that may affect the outcome.

Advantages of Quasi-Experimental Design

Quasi-experimental designs have several advantages over other research designs, such as:

  • Greater external validity : Quasi-experimental designs are more likely to have greater external validity than laboratory experiments because they are conducted in naturalistic settings. This means that the results are more likely to generalize to real-world situations.
  • Ethical considerations: Quasi-experimental designs often involve naturally occurring events, such as natural disasters or policy changes. This means that researchers do not need to manipulate variables, which can raise ethical concerns.
  • More practical: Quasi-experimental designs are often more practical than experimental designs because they are less expensive and easier to conduct. They can also be used to evaluate programs or policies that have already been implemented, which can save time and resources.
  • No random assignment: Quasi-experimental designs do not require random assignment, which can be difficult or impossible in some cases, such as when studying the effects of a natural disaster. This means that researchers can still make causal inferences, although they must use statistical techniques to control for potential confounding variables.
  • Greater generalizability : Quasi-experimental designs are often more generalizable than experimental designs because they include a wider range of participants and conditions. This can make the results more applicable to different populations and settings.

Limitations of Quasi-Experimental Design

There are several limitations associated with quasi-experimental designs, which include:

  • Lack of Randomization: Quasi-experimental designs do not involve randomization of participants into groups, which means that the groups being studied may differ in important ways that could affect the outcome of the study. This can lead to problems with internal validity and limit the ability to make causal inferences.
  • Selection Bias: Quasi-experimental designs may suffer from selection bias because participants are not randomly assigned to groups. Participants may self-select into groups or be assigned based on pre-existing characteristics, which may introduce bias into the study.
  • History and Maturation: Quasi-experimental designs are susceptible to history and maturation effects, where the passage of time or other events may influence the outcome of the study.
  • Lack of Control: Quasi-experimental designs may lack control over extraneous variables that could influence the outcome of the study. This can limit the ability to draw causal inferences from the study.
  • Limited Generalizability: Quasi-experimental designs may have limited generalizability because the results may only apply to the specific population and context being studied.

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Quasi-Experimental Design

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Quasi-Experimental Design is a unique research methodology because it is characterized by what is lacks. For example, Abraham & MacDonald (2011) state:

" Quasi-experimental research is similar to experimental research in that there is manipulation of an independent variable. It differs from experimental research because either there is no control group, no random selection, no random assignment, and/or no active manipulation. "

This type of research is often performed in cases where a control group cannot be created or random selection cannot be performed. This is often the case in certain medical and psychological studies. 

For more information on quasi-experimental design, review the resources below: 

Where to Start

Below are listed a few tools and online guides that can help you start your Quasi-experimental research. These include free online resources and resources available only through ISU Library.

  • Quasi-Experimental Research Designs by Bruce A. Thyer This pocket guide describes the logic, design, and conduct of the range of quasi-experimental designs, encompassing pre-experiments, quasi-experiments making use of a control or comparison group, and time-series designs. An introductory chapter describes the valuable role these types of studies have played in social work, from the 1930s to the present. Subsequent chapters delve into each design type's major features, the kinds of questions it is capable of answering, and its strengths and limitations.
  • Experimental and Quasi-Experimental Designs for Research by Donald T. Campbell; Julian C. Stanley. Call Number: Q175 C152e Written 1967 but still used heavily today, this book examines research designs for experimental and quasi-experimental research, with examples and judgments about each design's validity.

Online Resources

  • Quasi-Experimental Design From the Web Center for Social Research Methods, this is a very good overview of quasi-experimental design.
  • Experimental and Quasi-Experimental Research From Colorado State University.
  • Quasi-experimental design--Wikipedia, the free encyclopedia Wikipedia can be a useful place to start your research- check the citations at the bottom of the article for more information.
  • << Previous: Qualitative Research (General)
  • Next: Sampling >>
  • Last Updated: Dec 19, 2023 2:12 PM
  • URL: https://instr.iastate.libguides.com/researchmethods

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Chapter 7: Nonexperimental Research

Quasi-Experimental Research

Learning Objectives

  • Explain what quasi-experimental research is and distinguish it clearly from both experimental and correlational research.
  • Describe three different types of quasi-experimental research designs (nonequivalent groups, pretest-posttest, and interrupted time series) and identify examples of each one.

The prefix  quasi  means “resembling.” Thus quasi-experimental research is research that resembles experimental research but is not true experimental research. Although the independent variable is manipulated, participants are not randomly assigned to conditions or orders of conditions (Cook & Campbell, 1979). [1] Because the independent variable is manipulated before the dependent variable is measured, quasi-experimental research eliminates the directionality problem. But because participants are not randomly assigned—making it likely that there are other differences between conditions—quasi-experimental research does not eliminate the problem of confounding variables. In terms of internal validity, therefore, quasi-experiments are generally somewhere between correlational studies and true experiments.

Quasi-experiments are most likely to be conducted in field settings in which random assignment is difficult or impossible. They are often conducted to evaluate the effectiveness of a treatment—perhaps a type of psychotherapy or an educational intervention. There are many different kinds of quasi-experiments, but we will discuss just a few of the most common ones here.

Nonequivalent Groups Design

Recall that when participants in a between-subjects experiment are randomly assigned to conditions, the resulting groups are likely to be quite similar. In fact, researchers consider them to be equivalent. When participants are not randomly assigned to conditions, however, the resulting groups are likely to be dissimilar in some ways. For this reason, researchers consider them to be nonequivalent. A  nonequivalent groups design , then, is a between-subjects design in which participants have not been randomly assigned to conditions.

Imagine, for example, a researcher who wants to evaluate a new method of teaching fractions to third graders. One way would be to conduct a study with a treatment group consisting of one class of third-grade students and a control group consisting of another class of third-grade students. This design would be a nonequivalent groups design because the students are not randomly assigned to classes by the researcher, which means there could be important differences between them. For example, the parents of higher achieving or more motivated students might have been more likely to request that their children be assigned to Ms. Williams’s class. Or the principal might have assigned the “troublemakers” to Mr. Jones’s class because he is a stronger disciplinarian. Of course, the teachers’ styles, and even the classroom environments, might be very different and might cause different levels of achievement or motivation among the students. If at the end of the study there was a difference in the two classes’ knowledge of fractions, it might have been caused by the difference between the teaching methods—but it might have been caused by any of these confounding variables.

Of course, researchers using a nonequivalent groups design can take steps to ensure that their groups are as similar as possible. In the present example, the researcher could try to select two classes at the same school, where the students in the two classes have similar scores on a standardized math test and the teachers are the same sex, are close in age, and have similar teaching styles. Taking such steps would increase the internal validity of the study because it would eliminate some of the most important confounding variables. But without true random assignment of the students to conditions, there remains the possibility of other important confounding variables that the researcher was not able to control.

Pretest-Posttest Design

In a  pretest-posttest design , the dependent variable is measured once before the treatment is implemented and once after it is implemented. Imagine, for example, a researcher who is interested in the effectiveness of an antidrug education program on elementary school students’ attitudes toward illegal drugs. The researcher could measure the attitudes of students at a particular elementary school during one week, implement the antidrug program during the next week, and finally, measure their attitudes again the following week. The pretest-posttest design is much like a within-subjects experiment in which each participant is tested first under the control condition and then under the treatment condition. It is unlike a within-subjects experiment, however, in that the order of conditions is not counterbalanced because it typically is not possible for a participant to be tested in the treatment condition first and then in an “untreated” control condition.

If the average posttest score is better than the average pretest score, then it makes sense to conclude that the treatment might be responsible for the improvement. Unfortunately, one often cannot conclude this with a high degree of certainty because there may be other explanations for why the posttest scores are better. One category of alternative explanations goes under the name of  history . Other things might have happened between the pretest and the posttest. Perhaps an antidrug program aired on television and many of the students watched it, or perhaps a celebrity died of a drug overdose and many of the students heard about it. Another category of alternative explanations goes under the name of  maturation . Participants might have changed between the pretest and the posttest in ways that they were going to anyway because they are growing and learning. If it were a yearlong program, participants might become less impulsive or better reasoners and this might be responsible for the change.

Another alternative explanation for a change in the dependent variable in a pretest-posttest design is  regression to the mean . This refers to the statistical fact that an individual who scores extremely on a variable on one occasion will tend to score less extremely on the next occasion. For example, a bowler with a long-term average of 150 who suddenly bowls a 220 will almost certainly score lower in the next game. Her score will “regress” toward her mean score of 150. Regression to the mean can be a problem when participants are selected for further study  because  of their extreme scores. Imagine, for example, that only students who scored especially low on a test of fractions are given a special training program and then retested. Regression to the mean all but guarantees that their scores will be higher even if the training program has no effect. A closely related concept—and an extremely important one in psychological research—is  spontaneous remission . This is the tendency for many medical and psychological problems to improve over time without any form of treatment. The common cold is a good example. If one were to measure symptom severity in 100 common cold sufferers today, give them a bowl of chicken soup every day, and then measure their symptom severity again in a week, they would probably be much improved. This does not mean that the chicken soup was responsible for the improvement, however, because they would have been much improved without any treatment at all. The same is true of many psychological problems. A group of severely depressed people today is likely to be less depressed on average in 6 months. In reviewing the results of several studies of treatments for depression, researchers Michael Posternak and Ivan Miller found that participants in waitlist control conditions improved an average of 10 to 15% before they received any treatment at all (Posternak & Miller, 2001) [2] . Thus one must generally be very cautious about inferring causality from pretest-posttest designs.

Does Psychotherapy Work?

Early studies on the effectiveness of psychotherapy tended to use pretest-posttest designs. In a classic 1952 article, researcher Hans Eysenck summarized the results of 24 such studies showing that about two thirds of patients improved between the pretest and the posttest (Eysenck, 1952) [3] . But Eysenck also compared these results with archival data from state hospital and insurance company records showing that similar patients recovered at about the same rate  without  receiving psychotherapy. This parallel suggested to Eysenck that the improvement that patients showed in the pretest-posttest studies might be no more than spontaneous remission. Note that Eysenck did not conclude that psychotherapy was ineffective. He merely concluded that there was no evidence that it was, and he wrote of “the necessity of properly planned and executed experimental studies into this important field” (p. 323). You can read the entire article here: Classics in the History of Psychology .

Fortunately, many other researchers took up Eysenck’s challenge, and by 1980 hundreds of experiments had been conducted in which participants were randomly assigned to treatment and control conditions, and the results were summarized in a classic book by Mary Lee Smith, Gene Glass, and Thomas Miller (Smith, Glass, & Miller, 1980) [4] . They found that overall psychotherapy was quite effective, with about 80% of treatment participants improving more than the average control participant. Subsequent research has focused more on the conditions under which different types of psychotherapy are more or less effective.

Interrupted Time Series Design

A variant of the pretest-posttest design is the  interrupted time-series design . A time series is a set of measurements taken at intervals over a period of time. For example, a manufacturing company might measure its workers’ productivity each week for a year. In an interrupted time series-design, a time series like this one is “interrupted” by a treatment. In one classic example, the treatment was the reduction of the work shifts in a factory from 10 hours to 8 hours (Cook & Campbell, 1979) [5] . Because productivity increased rather quickly after the shortening of the work shifts, and because it remained elevated for many months afterward, the researcher concluded that the shortening of the shifts caused the increase in productivity. Notice that the interrupted time-series design is like a pretest-posttest design in that it includes measurements of the dependent variable both before and after the treatment. It is unlike the pretest-posttest design, however, in that it includes multiple pretest and posttest measurements.

Figure 7.3 shows data from a hypothetical interrupted time-series study. The dependent variable is the number of student absences per week in a research methods course. The treatment is that the instructor begins publicly taking attendance each day so that students know that the instructor is aware of who is present and who is absent. The top panel of  Figure 7.3 shows how the data might look if this treatment worked. There is a consistently high number of absences before the treatment, and there is an immediate and sustained drop in absences after the treatment. The bottom panel of  Figure 7.3 shows how the data might look if this treatment did not work. On average, the number of absences after the treatment is about the same as the number before. This figure also illustrates an advantage of the interrupted time-series design over a simpler pretest-posttest design. If there had been only one measurement of absences before the treatment at Week 7 and one afterward at Week 8, then it would have looked as though the treatment were responsible for the reduction. The multiple measurements both before and after the treatment suggest that the reduction between Weeks 7 and 8 is nothing more than normal week-to-week variation.

Image description available

Combination Designs

A type of quasi-experimental design that is generally better than either the nonequivalent groups design or the pretest-posttest design is one that combines elements of both. There is a treatment group that is given a pretest, receives a treatment, and then is given a posttest. But at the same time there is a control group that is given a pretest, does  not  receive the treatment, and then is given a posttest. The question, then, is not simply whether participants who receive the treatment improve but whether they improve  more  than participants who do not receive the treatment.

Imagine, for example, that students in one school are given a pretest on their attitudes toward drugs, then are exposed to an antidrug program, and finally are given a posttest. Students in a similar school are given the pretest, not exposed to an antidrug program, and finally are given a posttest. Again, if students in the treatment condition become more negative toward drugs, this change in attitude could be an effect of the treatment, but it could also be a matter of history or maturation. If it really is an effect of the treatment, then students in the treatment condition should become more negative than students in the control condition. But if it is a matter of history (e.g., news of a celebrity drug overdose) or maturation (e.g., improved reasoning), then students in the two conditions would be likely to show similar amounts of change. This type of design does not completely eliminate the possibility of confounding variables, however. Something could occur at one of the schools but not the other (e.g., a student drug overdose), so students at the first school would be affected by it while students at the other school would not.

Finally, if participants in this kind of design are randomly assigned to conditions, it becomes a true experiment rather than a quasi experiment. In fact, it is the kind of experiment that Eysenck called for—and that has now been conducted many times—to demonstrate the effectiveness of psychotherapy.

Key Takeaways

  • Quasi-experimental research involves the manipulation of an independent variable without the random assignment of participants to conditions or orders of conditions. Among the important types are nonequivalent groups designs, pretest-posttest, and interrupted time-series designs.
  • Quasi-experimental research eliminates the directionality problem because it involves the manipulation of the independent variable. It does not eliminate the problem of confounding variables, however, because it does not involve random assignment to conditions. For these reasons, quasi-experimental research is generally higher in internal validity than correlational studies but lower than true experiments.
  • Practice: Imagine that two professors decide to test the effect of giving daily quizzes on student performance in a statistics course. They decide that Professor A will give quizzes but Professor B will not. They will then compare the performance of students in their two sections on a common final exam. List five other variables that might differ between the two sections that could affect the results.
  • regression to the mean
  • spontaneous remission

Image Descriptions

Figure 7.3 image description: Two line graphs charting the number of absences per week over 14 weeks. The first 7 weeks are without treatment and the last 7 weeks are with treatment. In the first line graph, there are between 4 to 8 absences each week. After the treatment, the absences drop to 0 to 3 each week, which suggests the treatment worked. In the second line graph, there is no noticeable change in the number of absences per week after the treatment, which suggests the treatment did not work. [Return to Figure 7.3]

  • Cook, T. D., & Campbell, D. T. (1979). Quasi-experimentation: Design & analysis issues in field settings . Boston, MA: Houghton Mifflin. ↵
  • Posternak, M. A., & Miller, I. (2001). Untreated short-term course of major depression: A meta-analysis of studies using outcomes from studies using wait-list control groups. Journal of Affective Disorders, 66 , 139–146. ↵
  • Eysenck, H. J. (1952). The effects of psychotherapy: An evaluation. Journal of Consulting Psychology, 16 , 319–324. ↵
  • Smith, M. L., Glass, G. V., & Miller, T. I. (1980). The benefits of psychotherapy . Baltimore, MD: Johns Hopkins University Press. ↵

A between-subjects design in which participants have not been randomly assigned to conditions.

The dependent variable is measured once before the treatment is implemented and once after it is implemented.

A category of alternative explanations for differences between scores such as events that happened between the pretest and posttest, unrelated to the study.

An alternative explanation that refers to how the participants might have changed between the pretest and posttest in ways that they were going to anyway because they are growing and learning.

The statistical fact that an individual who scores extremely on a variable on one occasion will tend to score less extremely on the next occasion.

The tendency for many medical and psychological problems to improve over time without any form of treatment.

A set of measurements taken at intervals over a period of time that are interrupted by a treatment.

Research Methods in Psychology - 2nd Canadian Edition Copyright © 2015 by Paul C. Price, Rajiv Jhangiani, & I-Chant A. Chiang is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License , except where otherwise noted.

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8.2 Quasi-experimental and pre-experimental designs

Learning objectives.

  • Identify and describe the various types of quasi-experimental designs
  • Distinguish true experimental designs from quasi-experimental and pre-experimental designs
  • Identify and describe the various types of quasi-experimental and pre-experimental designs

As we discussed in the previous section, time, funding, and ethics may limit a researcher’s ability to conduct a true experiment. For researchers in the medical sciences and social work, conducting a true experiment could require denying needed treatment to clients, which is a clear ethical violation. Even those whose research may not involve the administration of needed medications or treatments may be limited in their ability to conduct a classic experiment. When true experiments are not possible, researchers often use quasi-experimental designs.

Quasi-experimental designs

Quasi-experimental designs are similar to true experiments, but they lack random assignment to experimental and control groups. Quasi-experimental designs have a comparison group that is similar to a control group except assignment to the comparison group is not determined by random assignment. The most basic of these quasi-experimental designs is the nonequivalent comparison groups design (Rubin & Babbie, 2017).  The nonequivalent comparison group design looks a lot like the classic experimental design, except it does not use random assignment. In many cases, these groups may already exist. For example, a researcher might conduct research at two different agency sites, one of which receives the intervention and the other does not. No one was assigned to treatment or comparison groups. Those groupings existed prior to the study. While this method is more convenient for real-world research, it is less likely that that the groups are comparable than if they had been determined by random assignment. Perhaps the treatment group has a characteristic that is unique–for example, higher income or different diagnoses–that make the treatment more effective.

Quasi-experiments are particularly useful in social welfare policy research. Social welfare policy researchers often look for what are termed natural experiments , or situations in which comparable groups are created by differences that already occur in the real world. Natural experiments are a feature of the social world that allows researchers to use the logic of experimental design to investigate the connection between variables. For example, Stratmann and Wille (2016) were interested in the effects of a state healthcare policy called Certificate of Need on the quality of hospitals. They clearly could not randomly assign states to adopt one set of policies or another. Instead, researchers used hospital referral regions, or the areas from which hospitals draw their patients, that spanned across state lines. Because the hospitals were in the same referral region, researchers could be pretty sure that the client characteristics were pretty similar. In this way, they could classify patients in experimental and comparison groups without dictating state policy or telling people where to live.

random assignment in quasi experimental

Matching is another approach in quasi-experimental design for assigning people to experimental and comparison groups. It begins with researchers thinking about what variables are important in their study, particularly demographic variables or attributes that might impact their dependent variable. Individual matching involves pairing participants with similar attributes. Then, the matched pair is split—with one participant going to the experimental group and the other to the comparison group. An ex post facto control group , in contrast, is when a researcher matches individuals after the intervention is administered to some participants. Finally, researchers may engage in aggregate matching , in which the comparison group is determined to be similar on important variables.

Time series design

There are many different quasi-experimental designs in addition to the nonequivalent comparison group design described earlier. Describing all of them is beyond the scope of this textbook, but one more design is worth mentioning. The time series design uses multiple observations before and after an intervention. In some cases, experimental and comparison groups are used. In other cases where that is not feasible, a single experimental group is used. By using multiple observations before and after the intervention, the researcher can better understand the true value of the dependent variable in each participant before the intervention starts. Additionally, multiple observations afterwards allow the researcher to see whether the intervention had lasting effects on participants. Time series designs are similar to single-subjects designs, which we will discuss in Chapter 15.

Pre-experimental design

When true experiments and quasi-experiments are not possible, researchers may turn to a pre-experimental design (Campbell & Stanley, 1963).  Pre-experimental designs are called such because they often happen as a pre-cursor to conducting a true experiment.  Researchers want to see if their interventions will have some effect on a small group of people before they seek funding and dedicate time to conduct a true experiment. Pre-experimental designs, thus, are usually conducted as a first step towards establishing the evidence for or against an intervention. However, this type of design comes with some unique disadvantages, which we’ll describe below.

A commonly used type of pre-experiment is the one-group pretest post-test design . In this design, pre- and posttests are both administered, but there is no comparison group to which to compare the experimental group. Researchers may be able to make the claim that participants receiving the treatment experienced a change in the dependent variable, but they cannot begin to claim that the change was the result of the treatment without a comparison group.   Imagine if the students in your research class completed a questionnaire about their level of stress at the beginning of the semester.  Then your professor taught you mindfulness techniques throughout the semester.  At the end of the semester, she administers the stress survey again.  What if levels of stress went up?  Could she conclude that the mindfulness techniques caused stress?  Not without a comparison group!  If there was a comparison group, she would be able to recognize that all students experienced higher stress at the end of the semester than the beginning of the semester, not just the students in her research class.

In cases where the administration of a pretest is cost prohibitive or otherwise not possible, a one- shot case study design might be used. In this instance, no pretest is administered, nor is a comparison group present. If we wished to measure the impact of a natural disaster, such as Hurricane Katrina for example, we might conduct a pre-experiment by identifying  a community that was hit by the hurricane and then measuring the levels of stress in the community.  Researchers using this design must be extremely cautious about making claims regarding the effect of the treatment or stimulus. They have no idea what the levels of stress in the community were before the hurricane hit nor can they compare the stress levels to a community that was not affected by the hurricane.  Nonetheless, this design can be useful for exploratory studies aimed at testing a measures or the feasibility of further study.

In our example of the study of the impact of Hurricane Katrina, a researcher might choose to examine the effects of the hurricane by identifying a group from a community that experienced the hurricane and a comparison group from a similar community that had not been hit by the hurricane. This study design, called a static group comparison , has the advantage of including a comparison group that did not experience the stimulus (in this case, the hurricane). Unfortunately, the design only uses for post-tests, so it is not possible to know if the groups were comparable before the stimulus or intervention.  As you might have guessed from our example, static group comparisons are useful in cases where a researcher cannot control or predict whether, when, or how the stimulus is administered, as in the case of natural disasters.

As implied by the preceding examples where we considered studying the impact of Hurricane Katrina, experiments, quasi-experiments, and pre-experiments do not necessarily need to take place in the controlled setting of a lab. In fact, many applied researchers rely on experiments to assess the impact and effectiveness of various programs and policies. You might recall our discussion of arresting perpetrators of domestic violence in Chapter 2, which is an excellent example of an applied experiment. Researchers did not subject participants to conditions in a lab setting; instead, they applied their stimulus (in this case, arrest) to some subjects in the field and they also had a control group in the field that did not receive the stimulus (and therefore were not arrested).

Key Takeaways

  • Quasi-experimental designs do not use random assignment.
  • Comparison groups are used in quasi-experiments.
  • Matching is a way of improving the comparability of experimental and comparison groups.
  • Quasi-experimental designs and pre-experimental designs are often used when experimental designs are impractical.
  • Quasi-experimental and pre-experimental designs may be easier to carry out, but they lack the rigor of true experiments.
  • Aggregate matching – when the comparison group is determined to be similar to the experimental group along important variables
  • Comparison group – a group in quasi-experimental design that does not receive the experimental treatment; it is similar to a control group except assignment to the comparison group is not determined by random assignment
  • Ex post facto control group – a control group created when a researcher matches individuals after the intervention is administered
  • Individual matching – pairing participants with similar attributes for the purpose of assignment to groups
  • Natural experiments – situations in which comparable groups are created by differences that already occur in the real world
  • Nonequivalent comparison group design – a quasi-experimental design similar to a classic experimental design but without random assignment
  • One-group pretest post-test design – a pre-experimental design that applies an intervention to one group but also includes a pretest
  • One-shot case study – a pre-experimental design that applies an intervention to only one group without a pretest
  • Pre-experimental designs – a variation of experimental design that lacks the rigor of experiments and is often used before a true experiment is conducted
  • Quasi-experimental design – designs lack random assignment to experimental and control groups
  • Static group design – uses an experimental group and a comparison group, without random assignment and pretesting
  • Time series design – a quasi-experimental design that uses multiple observations before and after an intervention

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Experiments and quasi-experiments.

This page includes an explanation of the types, key components, validity, ethics, and advantages and disadvantages of experimental design.

An experiment is a study in which the researcher manipulates the level of some independent variable and then measures the outcome. Experiments are powerful techniques for evaluating cause-and-effect relationships. Many researchers consider experiments the "gold standard" against which all other research designs should be judged. Experiments are conducted both in the laboratory and in real life situations.

Types of Experimental Design

There are two basic types of research design:

  • True experiments
  • Quasi-experiments

The purpose of both is to examine the cause of certain phenomena.

True experiments, in which all the important factors that might affect the phenomena of interest are completely controlled, are the preferred design. Often, however, it is not possible or practical to control all the key factors, so it becomes necessary to implement a quasi-experimental research design.

Similarities between true and quasi-experiments:

  • Study participants are subjected to some type of treatment or condition
  • Some outcome of interest is measured
  • The researchers test whether differences in this outcome are related to the treatment

Differences between true experiments and quasi-experiments:

  • In a true experiment, participants are randomly assigned to either the treatment or the control group, whereas they are not assigned randomly in a quasi-experiment
  • In a quasi-experiment, the control and treatment groups differ not only in terms of the experimental treatment they receive, but also in other, often unknown or unknowable, ways. Thus, the researcher must try to statistically control for as many of these differences as possible
  • Because control is lacking in quasi-experiments, there may be several "rival hypotheses" competing with the experimental manipulation as explanations for observed results

Key Components of Experimental Research Design

The manipulation of predictor variables.

In an experiment, the researcher manipulates the factor that is hypothesized to affect the outcome of interest. The factor that is being manipulated is typically referred to as the treatment or intervention. The researcher may manipulate whether research subjects receive a treatment (e.g., antidepressant medicine: yes or no) and the level of treatment (e.g., 50 mg, 75 mg, 100 mg, and 125 mg).

Suppose, for example, a group of researchers was interested in the causes of maternal employment. They might hypothesize that the provision of government-subsidized child care would promote such employment. They could then design an experiment in which some subjects would be provided the option of government-funded child care subsidies and others would not. The researchers might also manipulate the value of the child care subsidies in order to determine if higher subsidy values might result in different levels of maternal employment.

Random Assignment

  • Study participants are randomly assigned to different treatment groups
  • All participants have the same chance of being in a given condition
  • Participants are assigned to either the group that receives the treatment, known as the "experimental group" or "treatment group," or to the group which does not receive the treatment, referred to as the "control group"
  • Random assignment neutralizes factors other than the independent and dependent variables, making it possible to directly infer cause and effect

Random Sampling

Traditionally, experimental researchers have used convenience sampling to select study participants. However, as research methods have become more rigorous, and the problems with generalizing from a convenience sample to the larger population have become more apparent, experimental researchers are increasingly turning to random sampling. In experimental policy research studies, participants are often randomly selected from program administrative databases and randomly assigned to the control or treatment groups.

Validity of Results

The two types of validity of experiments are internal and external. It is often difficult to achieve both in social science research experiments.

Internal Validity

  • When an experiment is internally valid, we are certain that the independent variable (e.g., child care subsidies) caused the outcome of the study (e.g., maternal employment)
  • When subjects are randomly assigned to treatment or control groups, we can assume that the independent variable caused the observed outcomes because the two groups should not have differed from one another at the start of the experiment
  • For example, take the child care subsidy example above. Since research subjects were randomly assigned to the treatment (child care subsidies available) and control (no child care subsidies available) groups, the two groups should not have differed at the outset of the study. If, after the intervention, mothers in the treatment group were more likely to be working, we can assume that the availability of child care subsidies promoted maternal employment

One potential threat to internal validity in experiments occurs when participants either drop out of the study or refuse to participate in the study. If particular types of individuals drop out or refuse to participate more often than individuals with other characteristics, this is called differential attrition. For example, suppose an experiment was conducted to assess the effects of a new reading curriculum. If the new curriculum was so tough that many of the slowest readers dropped out of school, the school with the new curriculum would experience an increase in the average reading scores. The reason they experienced an increase in reading scores, however, is because the worst readers left the school, not because the new curriculum improved students' reading skills.

External Validity

  • External validity is also of particular concern in social science experiments
  • It can be very difficult to generalize experimental results to groups that were not included in the study
  • Studies that randomly select participants from the most diverse and representative populations are more likely to have external validity
  • The use of random sampling techniques makes it easier to generalize the results of studies to other groups

For example, a research study shows that a new curriculum improved reading comprehension of third-grade children in Iowa. To assess the study's external validity, you would ask whether this new curriculum would also be effective with third graders in New York or with children in other elementary grades.

Glossary terms related to validity:

  • internal validity
  • external validity
  • differential attrition

It is particularly important in experimental research to follow ethical guidelines. Protecting the health and safety of research subjects is imperative. In order to assure subject safety, all researchers should have their project reviewed by the Institutional Review Boards (IRBS). The  National Institutes of Health  supplies strict guidelines for project approval. Many of these guidelines are based on the  Belmont Report  (pdf).

The basic ethical principles:

  • Respect for persons  -- requires that research subjects are not coerced into participating in a study and requires the protection of research subjects who have diminished autonomy
  • Beneficence  -- requires that experiments do not harm research subjects, and that researchers minimize the risks for subjects while maximizing the benefits for them
  • Justice  -- requires that all forms of differential treatment among research subjects be justified

Advantages and Disadvantages of Experimental Design

The environment in which the research takes place can often be carefully controlled. Consequently, it is easier to estimate the true effect of the variable of interest on the outcome of interest.

Disadvantages

It is often difficult to assure the external validity of the experiment, due to the frequently nonrandom selection processes and the artificial nature of the experimental context.

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An Introduction to Quasi-Experimental Design

An Introduction to Quasi-Experimental Design

3-minute read

  • 9th January 2022

If you’re a researcher or student in the sciences, you’ll probably come across the term “quasi-experimental design” at some point. But what exactly does it mean?

In this post, we’ll guide you through the different forms of quasi-experimental design and how it compares to true experiments.

What is Quasi-Experimental Design?

Quasi-experimental design (QED) is a research design method that’s useful when regular experimental conditions are impractical or unethical.

Both quasi-experimental designs and true experiments show a cause-and-effect relationship between a dependent and independent variable . Participants in a true experiment are randomly assigned to different treatment groups. The quasi-experimental design, on the other hand, assigns groups based on criteria instead of randomly.

Quasi-Experimental Design Vs. True Experimental Design

The main difference between a quasi-experimental and true experimental design is that in the former, groups aren’t randomly assigned. There are also some other key differences between these research methods.

True experimental design involves:

●     Having control as a researcher over the design of the treatment or program that participants receive (i.e., the independent variable)

●     Control variables as a necessary component

In contrast, a quasi-experimental design involves:

●     The researcher studying groups after they’ve received a treatment or program

●     Control variables as a common element but they aren’t necessary for the experiment to work

Examples of Experimental Design

Perhaps the easiest way to understand quasi-experimental design is to look at how it might be used in practice.

Let’s say you hypothesize that having access to free art lessons will improve the mental health of children from low-income families.

In a true experiment, you’d randomly assign participants to two groups: one that receives free art lessons and another that doesn’t.

However, it’s ethically questionable to deny one group of children access to something that might benefit them.

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Instead, you might decide to compare the data from a community that’s already offered free art classes to these children with that of a community that’s not yet done so.

This second example would be a quasi-experimental design.

Advantages and Disadvantages of Quasi-Experimental Design

Quasi-experimental design has some advantages and disadvantages you’ll need to consider when designing your research.

On the plus side, quasi-experimental design:

●     Has a higher external validity than true experimental design, as it usually involves real-world scenarios

●     Allows you to control for unexpected, confounding variables, resulting in a higher internal validity than other non-experimental methods of research

●     Enables the study of cause-and-effect relationships without the ethical issue of denying a treatment to those who may benefit from it

●     Does not require access to large-scale funding and other practical concerns, as the treatment has already been issued by others

The disadvantages of quasi-experimental design, however, include:

●     Lower internal validity than found in true experiments, as it’s more difficult to account for all confounding variables without using random assignment

●     The necessary data required for research potentially being inaccurate, outdated, or difficult to access

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12.2: Pre-experimental and quasi-experimental design

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  • Matthew DeCarlo
  • Radford University via Open Social Work Education

Learning Objectives

  • Identify and describe the various types of quasi-experimental designs
  • Distinguish true experimental designs from quasi-experimental and pre-experimental designs
  • Identify and describe the various types of quasi-experimental and pre-experimental designs

As we discussed in the previous section, time, funding, and ethics may limit a researcher’s ability to conduct a true experiment. For researchers in the medical sciences and social work, conducting a true experiment could require denying needed treatment to clients, which is a clear ethical violation. Even those whose research may not involve the administration of needed medications or treatments may be limited in their ability to conduct a classic experiment. When true experiments are not possible, researchers often use quasi-experimental designs.

Quasi-experimental designs are similar to true experiments, but they lack random assignment to experimental and control groups. The most basic of these quasi-experimental designs is the nonequivalent comparison groups design (Rubin & Babbie, 2017). [1] The nonequivalent comparison group design looks a lot like the classic experimental design, except it does not use random assignment. In many cases, these groups may already exist. For example, a researcher might conduct research at two different agency sites, one of which receives the intervention and the other does not. No one was assigned to treatment or comparison groups. Those groupings existed prior to the study. While this method is more convenient for real-world research, researchers cannot be sure that the groups are comparable. Perhaps the treatment group has a characteristic that is unique–for example, higher income or different diagnoses–that make the treatment more effective.

Quasi-experiments are particularly useful in social welfare policy research. Social welfare policy researchers like me often look for what are termed natural experiments , or situations in which comparable groups are created by differences that already occur in the real world. For example, Stratmann and Wille (2016) [2] were interested in the effects of a state healthcare policy called Certificate of Need on the quality of hospitals. They clearly cannot assign states to adopt one set of policies or another. Instead, researchers used hospital referral regions, or the areas from which hospitals draw their patients, that spanned across state lines. Because the hospitals were in the same referral region, researchers could be pretty sure that the client characteristics were pretty similar. In this way, they could classify patients in experimental and comparison groups without affecting policy or telling people where to live.

There are important examples of policy experiments that use random assignment, including the Oregon Medicaid experiment. In the Oregon Medicaid experiment, the wait list for Oregon was so long, state officials conducted a lottery to see who from the wait list would receive Medicaid (Baicker et al., 2013). [3] Researchers used the lottery as a natural experiment that included random assignment. People selected to be a part of Medicaid were the experimental group and those on the wait list were in the control group. There are some practical complications with using people on a wait list as a control group—most obviously, what happens when people on the wait list are accepted into the program while you’re still collecting data? Natural experiments aren’t a specific kind of experiment like quasi- or pre-experimental designs. Instead, they are more like a feature of the social world that allows researchers to use the logic of experimental design to investigate the connection between variables.

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Matching is another approach in quasi-experimental design to assigning experimental and comparison groups. Researchers should think about what variables are important in their study, particularly demographic variables or attributes that might impact their dependent variable. Individual matching involves pairing participants with similar attributes. When this is done at the beginning of an experiment, the matched pair is split—with one participant going to the experimental group and the other to the control group. An ex post facto control group , in contrast, is when a researcher matches individuals after the intervention is administered to some participants. Finally, researchers may engage in aggregate matching , in which the comparison group is determined to be similar on important variables.

There are many different quasi-experimental designs in addition to the nonequivalent comparison group design described earlier. Describing all of them is beyond the scope of this textbook, but one more design is worth mentioning. The time series design uses multiple observations before and after an intervention. In some cases, experimental and comparison groups are used. In other cases where that is not feasible, a single experimental group is used. By using multiple observations before and after the intervention, the researcher can better understand the true value of the dependent variable in each participant before the intervention starts. Additionally, multiple observations afterwards allow the researcher to see whether the intervention had lasting effects on participants. Time series designs are similar to single-subjects designs, which we will discuss in Chapter 15.

When true experiments and quasi-experiments are not possible, researchers may turn to a pre-experimental design (Campbell & Stanley, 1963). [4] Pre-experimental designs are called such because they often happen before a true experiment is conducted. Researchers want to see if their interventions will have some effect on a small group of people before they seek funding and dedicate time to conduct a true experiment. Pre-experimental designs, thus, are usually conducted as a first step towards establishing the evidence for or against an intervention. However, this type of design comes with some unique disadvantages, which we’ll describe as we review the pre-experimental designs available.

If we wished to measure the impact of a natural disaster, such as Hurricane Katrina for example, we might conduct a pre-experiment by identifying an experimental group from a community that experienced the hurricane and a control group from a similar community that had not been hit by the hurricane. This study design, called a static group comparison , has the advantage of including a comparison group that did not experience the stimulus (in this case, the hurricane). Unfortunately, it is difficult to know those groups are truly comparable because the experimental and control groups were determined by factors other than random assignment. Additionally, the design would only allow for posttests, unless one were lucky enough to be gathering the data already before Katrina. As you might have guessed from our example, static group comparisons are useful in cases where a researcher cannot control or predict whether, when, or how the stimulus is administered, as in the case of natural disasters.

In cases where the administration of the stimulus is quite costly or otherwise not possible, a one- shot case study design might be used. In this instance, no pretest is administered, nor is a control group present. In our example of the study of the impact of Hurricane Katrina, a researcher using this design would test the impact of Katrina only among a community that was hit by the hurricane and would not seek a comparison group from a community that did not experience the hurricane. Researchers using this design must be extremely cautious about making claims regarding the effect of the stimulus, though the design could be useful for exploratory studies aimed at testing one’s measures or the feasibility of further study.

Finally, if a researcher is unlikely to be able to identify a sample large enough to split into control and experimental groups, or if she simply doesn’t have access to a control group, the researcher might use a one-group pre-/posttest design. In this instance, pre- and posttests are both taken, but there is no control group to which to compare the experimental group. We might be able to study of the impact of Hurricane Katrina using this design if we’d been collecting data on the impacted communities prior to the hurricane. We could then collect similar data after the hurricane. Applying this design involves a bit of serendipity and chance. Without having collected data from impacted communities prior to the hurricane, we would be unable to employ a one- group pre-/posttest design to study Hurricane Katrina’s impact.

As implied by the preceding examples where we considered studying the impact of Hurricane Katrina, experiments do not necessarily need to take place in the controlled setting of a lab. In fact, many applied researchers rely on experiments to assess the impact and effectiveness of various programs and policies. You might recall our discussion of arresting perpetrators of domestic violence in Chapter 6, which is an excellent example of an applied experiment. Researchers did not subject participants to conditions in a lab setting; instead, they applied their stimulus (in this case, arrest) to some subjects in the field and they also had a control group in the field that did not receive the stimulus (and therefore were not arrested).

Key Takeaways

  • Quasi-experimental designs do not use random assignment.
  • Comparison groups are often used in quasi-experiments.
  • Matching is a way of improving the comparability of experimental and comparison groups.
  • Quasi-experimental designs and pre-experimental designs are often used when experimental designs are impractical.
  • Quasi-experimental and pre-experimental designs may be easier to carry out, but they lack the rigor of true experiments.
  • Aggregate matching- when the comparison group is determined to be similar to the experimental group along important variables
  • Ex post facto control group- a control group created when a researcher matches individuals after the intervention is administered
  • Individual matching- pairing participants with similar attributes for the purpose of assignment to groups
  • Natural experiments- situations in which comparable groups are created by differences that already occur in the real world
  • Nonequivalent comparison group design- a quasi-experimental design similar to a classic experimental design but without random assignment
  • One-group pre-/posttest design- a pre-experimental design that applies an intervention to one group but also includes a pretest
  • One-shot case study- a pre-experimental design that applies an intervention to only one group without a pretest
  • Pre-experimental designs- a variation of experimental design that lacks the rigor of experiments and is often used before a true experiment is conducted
  • Quasi-experimental design- designs lack random assignment to experimental and control groups
  • Static group design- uses an experimental group and a comparison group, without random assignment and pretesting
  • Time series design- a quasi-experimental design that uses multiple observations before and after an intervention

Image attributions

cat and kitten matching avocado costumes on the couch looking at the camera by Your Best Digs CC-BY-2.0

  • Rubin, C. & Babbie, S. (2017). Research methods for social work (9th edition) . Boston, MA: Cengage. ↵
  • Stratmann, T. & Wille, D. (2016). Certificate-of-need laws and hospital quality . Mercatus Center at George Mason University, Arlington, VA. Retrieved from: https://www.mercatus.org/system/files/mercatus-stratmann-wille-con-hospital-quality-v1.pdf ↵
  • Baicker, K., Taubman, S. L., Allen, H. L., Bernstein, M., Gruber, J. H., Newhouse, J. P., ... & Finkelstein, A. N. (2013). The Oregon experiment—effects of Medicaid on clinical outcomes. New England Journal of Medicine , 368 (18), 1713-1722. ↵
  • Campbell, D., & Stanley, J. (1963). Experimental and quasi-experimental designs for research . Chicago, IL: Rand McNally. ↵

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  • v.13(1); Jan-Feb 2006

The Use and Interpretation of Quasi-Experimental Studies in Medical Informatics

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Quasi-experimental study designs, often described as nonrandomized, pre-post intervention studies, are common in the medical informatics literature. Yet little has been written about the benefits and limitations of the quasi-experimental approach as applied to informatics studies. This paper outlines a relative hierarchy and nomenclature of quasi-experimental study designs that is applicable to medical informatics intervention studies. In addition, the authors performed a systematic review of two medical informatics journals, the Journal of the American Medical Informatics Association (JAMIA) and the International Journal of Medical Informatics (IJMI), to determine the number of quasi-experimental studies published and how the studies are classified on the above-mentioned relative hierarchy. They hope that future medical informatics studies will implement higher level quasi-experimental study designs that yield more convincing evidence for causal links between medical informatics interventions and outcomes.

Quasi-experimental studies encompass a broad range of nonrandomized intervention studies. These designs are frequently used when it is not logistically feasible or ethical to conduct a randomized controlled trial. Examples of quasi-experimental studies follow. As one example of a quasi-experimental study, a hospital introduces a new order-entry system and wishes to study the impact of this intervention on the number of medication-related adverse events before and after the intervention. As another example, an informatics technology group is introducing a pharmacy order-entry system aimed at decreasing pharmacy costs. The intervention is implemented and pharmacy costs before and after the intervention are measured.

In medical informatics, the quasi-experimental, sometimes called the pre-post intervention, design often is used to evaluate the benefits of specific interventions. The increasing capacity of health care institutions to collect routine clinical data has led to the growing use of quasi-experimental study designs in the field of medical informatics as well as in other medical disciplines. However, little is written about these study designs in the medical literature or in traditional epidemiology textbooks. 1 , 2 , 3 In contrast, the social sciences literature is replete with examples of ways to implement and improve quasi-experimental studies. 4 , 5 , 6

In this paper, we review the different pretest-posttest quasi-experimental study designs, their nomenclature, and the relative hierarchy of these designs with respect to their ability to establish causal associations between an intervention and an outcome. The example of a pharmacy order-entry system aimed at decreasing pharmacy costs will be used throughout this article to illustrate the different quasi-experimental designs. We discuss limitations of quasi-experimental designs and offer methods to improve them. We also perform a systematic review of four years of publications from two informatics journals to determine the number of quasi-experimental studies, classify these studies into their application domains, determine whether the potential limitations of quasi-experimental studies were acknowledged by the authors, and place these studies into the above-mentioned relative hierarchy.

The authors reviewed articles and book chapters on the design of quasi-experimental studies. 4 , 5 , 6 , 7 , 8 , 9 , 10 Most of the reviewed articles referenced two textbooks that were then reviewed in depth. 4 , 6

Key advantages and disadvantages of quasi-experimental studies, as they pertain to the study of medical informatics, were identified. The potential methodological flaws of quasi-experimental medical informatics studies, which have the potential to introduce bias, were also identified. In addition, a summary table outlining a relative hierarchy and nomenclature of quasi-experimental study designs is described. In general, the higher the design is in the hierarchy, the greater the internal validity that the study traditionally possesses because the evidence of the potential causation between the intervention and the outcome is strengthened. 4

We then performed a systematic review of four years of publications from two informatics journals. First, we determined the number of quasi-experimental studies. We then classified these studies on the above-mentioned hierarchy. We also classified the quasi-experimental studies according to their application domain. The categories of application domains employed were based on categorization used by Yearbooks of Medical Informatics 1992–2005 and were similar to the categories of application domains employed by Annual Symposiums of the American Medical Informatics Association. 11 The categories were (1) health and clinical management; (2) patient records; (3) health information systems; (4) medical signal processing and biomedical imaging; (5) decision support, knowledge representation, and management; (6) education and consumer informatics; and (7) bioinformatics. Because the quasi-experimental study design has recognized limitations, we sought to determine whether authors acknowledged the potential limitations of this design. Examples of acknowledgment included mention of lack of randomization, the potential for regression to the mean, the presence of temporal confounders and the mention of another design that would have more internal validity.

All original scientific manuscripts published between January 2000 and December 2003 in the Journal of the American Medical Informatics Association (JAMIA) and the International Journal of Medical Informatics (IJMI) were reviewed. One author (ADH) reviewed all the papers to identify the number of quasi-experimental studies. Other authors (ADH, JCM, JF) then independently reviewed all the studies identified as quasi-experimental. The three authors then convened as a group to resolve any disagreements in study classification, application domain, and acknowledgment of limitations.

Results and Discussion

What is a quasi-experiment.

Quasi-experiments are studies that aim to evaluate interventions but that do not use randomization. Similar to randomized trials, quasi-experiments aim to demonstrate causality between an intervention and an outcome. Quasi-experimental studies can use both preintervention and postintervention measurements as well as nonrandomly selected control groups.

Using this basic definition, it is evident that many published studies in medical informatics utilize the quasi-experimental design. Although the randomized controlled trial is generally considered to have the highest level of credibility with regard to assessing causality, in medical informatics, researchers often choose not to randomize the intervention for one or more reasons: (1) ethical considerations, (2) difficulty of randomizing subjects, (3) difficulty to randomize by locations (e.g., by wards), (4) small available sample size. Each of these reasons is discussed below.

Ethical considerations typically will not allow random withholding of an intervention with known efficacy. Thus, if the efficacy of an intervention has not been established, a randomized controlled trial is the design of choice to determine efficacy. But if the intervention under study incorporates an accepted, well-established therapeutic intervention, or if the intervention has either questionable efficacy or safety based on previously conducted studies, then the ethical issues of randomizing patients are sometimes raised. In the area of medical informatics, it is often believed prior to an implementation that an informatics intervention will likely be beneficial and thus medical informaticians and hospital administrators are often reluctant to randomize medical informatics interventions. In addition, there is often pressure to implement the intervention quickly because of its believed efficacy, thus not allowing researchers sufficient time to plan a randomized trial.

For medical informatics interventions, it is often difficult to randomize the intervention to individual patients or to individual informatics users. So while this randomization is technically possible, it is underused and thus compromises the eventual strength of concluding that an informatics intervention resulted in an outcome. For example, randomly allowing only half of medical residents to use pharmacy order-entry software at a tertiary care hospital is a scenario that hospital administrators and informatics users may not agree to for numerous reasons.

Similarly, informatics interventions often cannot be randomized to individual locations. Using the pharmacy order-entry system example, it may be difficult to randomize use of the system to only certain locations in a hospital or portions of certain locations. For example, if the pharmacy order-entry system involves an educational component, then people may apply the knowledge learned to nonintervention wards, thereby potentially masking the true effect of the intervention. When a design using randomized locations is employed successfully, the locations may be different in other respects (confounding variables), and this further complicates the analysis and interpretation.

In situations where it is known that only a small sample size will be available to test the efficacy of an intervention, randomization may not be a viable option. Randomization is beneficial because on average it tends to evenly distribute both known and unknown confounding variables between the intervention and control group. However, when the sample size is small, randomization may not adequately accomplish this balance. Thus, alternative design and analytical methods are often used in place of randomization when only small sample sizes are available.

What Are the Threats to Establishing Causality When Using Quasi-experimental Designs in Medical Informatics?

The lack of random assignment is the major weakness of the quasi-experimental study design. Associations identified in quasi-experiments meet one important requirement of causality since the intervention precedes the measurement of the outcome. Another requirement is that the outcome can be demonstrated to vary statistically with the intervention. Unfortunately, statistical association does not imply causality, especially if the study is poorly designed. Thus, in many quasi-experiments, one is most often left with the question: “Are there alternative explanations for the apparent causal association?” If these alternative explanations are credible, then the evidence of causation is less convincing. These rival hypotheses, or alternative explanations, arise from principles of epidemiologic study design.

Shadish et al. 4 outline nine threats to internal validity that are outlined in ▶ . Internal validity is defined as the degree to which observed changes in outcomes can be correctly inferred to be caused by an exposure or an intervention. In quasi-experimental studies of medical informatics, we believe that the methodological principles that most often result in alternative explanations for the apparent causal effect include (a) difficulty in measuring or controlling for important confounding variables, particularly unmeasured confounding variables, which can be viewed as a subset of the selection threat in ▶ ; (b) results being explained by the statistical principle of regression to the mean . Each of these latter two principles is discussed in turn.

Threats to Internal Validity

Adapted from Shadish et al. 4

An inability to sufficiently control for important confounding variables arises from the lack of randomization. A variable is a confounding variable if it is associated with the exposure of interest and is also associated with the outcome of interest; the confounding variable leads to a situation where a causal association between a given exposure and an outcome is observed as a result of the influence of the confounding variable. For example, in a study aiming to demonstrate that the introduction of a pharmacy order-entry system led to lower pharmacy costs, there are a number of important potential confounding variables (e.g., severity of illness of the patients, knowledge and experience of the software users, other changes in hospital policy) that may have differed in the preintervention and postintervention time periods ( ▶ ). In a multivariable regression, the first confounding variable could be addressed with severity of illness measures, but the second confounding variable would be difficult if not nearly impossible to measure and control. In addition, potential confounding variables that are unmeasured or immeasurable cannot be controlled for in nonrandomized quasi-experimental study designs and can only be properly controlled by the randomization process in randomized controlled trials.

An external file that holds a picture, illustration, etc.
Object name is 16f01.jpg

Example of confounding. To get the true effect of the intervention of interest, we need to control for the confounding variable.

Another important threat to establishing causality is regression to the mean. 12 , 13 , 14 This widespread statistical phenomenon can result in wrongly concluding that an effect is due to the intervention when in reality it is due to chance. The phenomenon was first described in 1886 by Francis Galton who measured the adult height of children and their parents. He noted that when the average height of the parents was greater than the mean of the population, the children tended to be shorter than their parents, and conversely, when the average height of the parents was shorter than the population mean, the children tended to be taller than their parents.

In medical informatics, what often triggers the development and implementation of an intervention is a rise in the rate above the mean or norm. For example, increasing pharmacy costs and adverse events may prompt hospital informatics personnel to design and implement pharmacy order-entry systems. If this rise in costs or adverse events is really just an extreme observation that is still within the normal range of the hospital's pharmaceutical costs (i.e., the mean pharmaceutical cost for the hospital has not shifted), then the statistical principle of regression to the mean predicts that these elevated rates will tend to decline even without intervention. However, often informatics personnel and hospital administrators cannot wait passively for this decline to occur. Therefore, hospital personnel often implement one or more interventions, and if a decline in the rate occurs, they may mistakenly conclude that the decline is causally related to the intervention. In fact, an alternative explanation for the finding could be regression to the mean.

What Are the Different Quasi-experimental Study Designs?

In the social sciences literature, quasi-experimental studies are divided into four study design groups 4 , 6 :

  • Quasi-experimental designs without control groups
  • Quasi-experimental designs that use control groups but no pretest
  • Quasi-experimental designs that use control groups and pretests
  • Interrupted time-series designs

There is a relative hierarchy within these categories of study designs, with category D studies being sounder than categories C, B, or A in terms of establishing causality. Thus, if feasible from a design and implementation point of view, investigators should aim to design studies that fall in to the higher rated categories. Shadish et al. 4 discuss 17 possible designs, with seven designs falling into category A, three designs in category B, and six designs in category C, and one major design in category D. In our review, we determined that most medical informatics quasi-experiments could be characterized by 11 of 17 designs, with six study designs in category A, one in category B, three designs in category C, and one design in category D because the other study designs were not used or feasible in the medical informatics literature. Thus, for simplicity, we have summarized the 11 study designs most relevant to medical informatics research in ▶ .

Relative Hierarchy of Quasi-experimental Designs

O = Observational Measurement; X = Intervention Under Study. Time moves from left to right.

The nomenclature and relative hierarchy were used in the systematic review of four years of JAMIA and the IJMI. Similar to the relative hierarchy that exists in the evidence-based literature that assigns a hierarchy to randomized controlled trials, cohort studies, case-control studies, and case series, the hierarchy in ▶ is not absolute in that in some cases, it may be infeasible to perform a higher level study. For example, there may be instances where an A6 design established stronger causality than a B1 design. 15 , 16 , 17

Quasi-experimental Designs without Control Groups

equation M1

Here, X is the intervention and O is the outcome variable (this notation is continued throughout the article). In this study design, an intervention (X) is implemented and a posttest observation (O1) is taken. For example, X could be the introduction of a pharmacy order-entry intervention and O1 could be the pharmacy costs following the intervention. This design is the weakest of the quasi-experimental designs that are discussed in this article. Without any pretest observations or a control group, there are multiple threats to internal validity. Unfortunately, this study design is often used in medical informatics when new software is introduced since it may be difficult to have pretest measurements due to time, technical, or cost constraints.

equation M2

This is a commonly used study design. A single pretest measurement is taken (O1), an intervention (X) is implemented, and a posttest measurement is taken (O2). In this instance, period O1 frequently serves as the “control” period. For example, O1 could be pharmacy costs prior to the intervention, X could be the introduction of a pharmacy order-entry system, and O2 could be the pharmacy costs following the intervention. Including a pretest provides some information about what the pharmacy costs would have been had the intervention not occurred.

equation M3

The advantage of this study design over A2 is that adding a second pretest prior to the intervention helps provide evidence that can be used to refute the phenomenon of regression to the mean and confounding as alternative explanations for any observed association between the intervention and the posttest outcome. For example, in a study where a pharmacy order-entry system led to lower pharmacy costs (O3 < O2 and O1), if one had two preintervention measurements of pharmacy costs (O1 and O2) and they were both elevated, this would suggest that there was a decreased likelihood that O3 is lower due to confounding and regression to the mean. Similarly, extending this study design by increasing the number of measurements postintervention could also help to provide evidence against confounding and regression to the mean as alternate explanations for observed associations.

equation M4

This design involves the inclusion of a nonequivalent dependent variable ( b ) in addition to the primary dependent variable ( a ). Variables a and b should assess similar constructs; that is, the two measures should be affected by similar factors and confounding variables except for the effect of the intervention. Variable a is expected to change because of the intervention X, whereas variable b is not. Taking our example, variable a could be pharmacy costs and variable b could be the length of stay of patients. If our informatics intervention is aimed at decreasing pharmacy costs, we would expect to observe a decrease in pharmacy costs but not in the average length of stay of patients. However, a number of important confounding variables, such as severity of illness and knowledge of software users, might affect both outcome measures. Thus, if the average length of stay did not change following the intervention but pharmacy costs did, then the data are more convincing than if just pharmacy costs were measured.

The Removed-Treatment Design

equation M5

This design adds a third posttest measurement (O3) to the one-group pretest-posttest design and then removes the intervention before a final measure (O4) is made. The advantage of this design is that it allows one to test hypotheses about the outcome in the presence of the intervention and in the absence of the intervention. Thus, if one predicts a decrease in the outcome between O1 and O2 (after implementation of the intervention), then one would predict an increase in the outcome between O3 and O4 (after removal of the intervention). One caveat is that if the intervention is thought to have persistent effects, then O4 needs to be measured after these effects are likely to have disappeared. For example, a study would be more convincing if it demonstrated that pharmacy costs decreased after pharmacy order-entry system introduction (O2 and O3 less than O1) and that when the order-entry system was removed or disabled, the costs increased (O4 greater than O2 and O3 and closer to O1). In addition, there are often ethical issues in this design in terms of removing an intervention that may be providing benefit.

The Repeated-Treatment Design

equation M6

The advantage of this design is that it demonstrates reproducibility of the association between the intervention and the outcome. For example, the association is more likely to be causal if one demonstrates that a pharmacy order-entry system results in decreased pharmacy costs when it is first introduced and again when it is reintroduced following an interruption of the intervention. As for design A5, the assumption must be made that the effect of the intervention is transient, which is most often applicable to medical informatics interventions. Because in this design, subjects may serve as their own controls, this may yield greater statistical efficiency with fewer numbers of subjects.

Quasi-experimental Designs That Use a Control Group but No Pretest

equation M7

An intervention X is implemented for one group and compared to a second group. The use of a comparison group helps prevent certain threats to validity including the ability to statistically adjust for confounding variables. Because in this study design, the two groups may not be equivalent (assignment to the groups is not by randomization), confounding may exist. For example, suppose that a pharmacy order-entry intervention was instituted in the medical intensive care unit (MICU) and not the surgical intensive care unit (SICU). O1 would be pharmacy costs in the MICU after the intervention and O2 would be pharmacy costs in the SICU after the intervention. The absence of a pretest makes it difficult to know whether a change has occurred in the MICU. Also, the absence of pretest measurements comparing the SICU to the MICU makes it difficult to know whether differences in O1 and O2 are due to the intervention or due to other differences in the two units (confounding variables).

Quasi-experimental Designs That Use Control Groups and Pretests

The reader should note that with all the studies in this category, the intervention is not randomized. The control groups chosen are comparison groups. Obtaining pretest measurements on both the intervention and control groups allows one to assess the initial comparability of the groups. The assumption is that if the intervention and the control groups are similar at the pretest, the smaller the likelihood there is of important confounding variables differing between the two groups.

equation M8

The use of both a pretest and a comparison group makes it easier to avoid certain threats to validity. However, because the two groups are nonequivalent (assignment to the groups is not by randomization), selection bias may exist. Selection bias exists when selection results in differences in unit characteristics between conditions that may be related to outcome differences. For example, suppose that a pharmacy order-entry intervention was instituted in the MICU and not the SICU. If preintervention pharmacy costs in the MICU (O1a) and SICU (O1b) are similar, it suggests that it is less likely that there are differences in the important confounding variables between the two units. If MICU postintervention costs (O2a) are less than preintervention MICU costs (O1a), but SICU costs (O1b) and (O2b) are similar, this suggests that the observed outcome may be causally related to the intervention.

equation M9

In this design, the pretests are administered at two different times. The main advantage of this design is that it controls for potentially different time-varying confounding effects in the intervention group and the comparison group. In our example, measuring points O1 and O2 would allow for the assessment of time-dependent changes in pharmacy costs, e.g., due to differences in experience of residents, preintervention between the intervention and control group, and whether these changes were similar or different.

equation M10

With this study design, the researcher administers an intervention at a later time to a group that initially served as a nonintervention control. The advantage of this design over design C2 is that it demonstrates reproducibility in two different settings. This study design is not limited to two groups; in fact, the study results have greater validity if the intervention effect is replicated in different groups at multiple times. In the example of a pharmacy order-entry system, one could implement or intervene in the MICU and then at a later time, intervene in the SICU. This latter design is often very applicable to medical informatics where new technology and new software is often introduced or made available gradually.

Interrupted Time-Series Designs

equation M11

An interrupted time-series design is one in which a string of consecutive observations equally spaced in time is interrupted by the imposition of a treatment or intervention. The advantage of this design is that with multiple measurements both pre- and postintervention, it is easier to address and control for confounding and regression to the mean. In addition, statistically, there is a more robust analytic capability, and there is the ability to detect changes in the slope or intercept as a result of the intervention in addition to a change in the mean values. 18 A change in intercept could represent an immediate effect while a change in slope could represent a gradual effect of the intervention on the outcome. In the example of a pharmacy order-entry system, O1 through O5 could represent monthly pharmacy costs preintervention and O6 through O10 monthly pharmacy costs post the introduction of the pharmacy order-entry system. Interrupted time-series designs also can be further strengthened by incorporating many of the design features previously mentioned in other categories (such as removal of the treatment, inclusion of a nondependent outcome variable, or the addition of a control group).

Systematic Review Results

The results of the systematic review are in ▶ . In the four-year period of JAMIA publications that the authors reviewed, 25 quasi-experimental studies among 22 articles were published. Of these 25, 15 studies were of category A, five studies were of category B, two studies were of category C, and no studies were of category D. Although there were no studies of category D (interrupted time-series analyses), three of the studies classified as category A had data collected that could have been analyzed as an interrupted time-series analysis. Nine of the 25 studies (36%) mentioned at least one of the potential limitations of the quasi-experimental study design. In the four-year period of IJMI publications reviewed by the authors, nine quasi-experimental studies among eight manuscripts were published. Of these nine, five studies were of category A, one of category B, one of category C, and two of category D. Two of the nine studies (22%) mentioned at least one of the potential limitations of the quasi-experimental study design.

Systematic Review of Four Years of Quasi-designs in JAMIA

JAMIA = Journal of the American Medical Informatics Association; IJMI = International Journal of Medical Informatics.

In addition, three studies from JAMIA were based on a counterbalanced design. A counterbalanced design is a higher order study design than other studies in category A. The counterbalanced design is sometimes referred to as a Latin-square arrangement. In this design, all subjects receive all the different interventions but the order of intervention assignment is not random. 19 This design can only be used when the intervention is compared against some existing standard, for example, if a new PDA-based order entry system is to be compared to a computer terminal–based order entry system. In this design, all subjects receive the new PDA-based order entry system and the old computer terminal-based order entry system. The counterbalanced design is a within-participants design, where the order of the intervention is varied (e.g., one group is given software A followed by software B and another group is given software B followed by software A). The counterbalanced design is typically used when the available sample size is small, thus preventing the use of randomization. This design also allows investigators to study the potential effect of ordering of the informatics intervention.

Although quasi-experimental study designs are ubiquitous in the medical informatics literature, as evidenced by 34 studies in the past four years of the two informatics journals, little has been written about the benefits and limitations of the quasi-experimental approach. As we have outlined in this paper, a relative hierarchy and nomenclature of quasi-experimental study designs exist, with some designs being more likely than others to permit causal interpretations of observed associations. Strengths and limitations of a particular study design should be discussed when presenting data collected in the setting of a quasi-experimental study. Future medical informatics investigators should choose the strongest design that is feasible given the particular circumstances.

Supplementary Material

Dr. Harris was supported by NIH grants K23 AI01752-01A1 and R01 AI60859-01A1. Dr. Perencevich was supported by a VA Health Services Research and Development Service (HSR&D) Research Career Development Award (RCD-02026-1). Dr. Finkelstein was supported by NIH grant RO1 HL71690.

Experimental vs Quasi-Experimental Design: Which to Choose?

Here’s a table that summarizes the similarities and differences between an experimental and a quasi-experimental study design:

What is a quasi-experimental design?

A quasi-experimental design is a non-randomized study design used to evaluate the effect of an intervention. The intervention can be a training program, a policy change or a medical treatment.

Unlike a true experiment, in a quasi-experimental study the choice of who gets the intervention and who doesn’t is not randomized. Instead, the intervention can be assigned to participants according to their choosing or that of the researcher, or by using any method other than randomness.

Having a control group is not required, but if present, it provides a higher level of evidence for the relationship between the intervention and the outcome.

(for more information, I recommend my other article: Understand Quasi-Experimental Design Through an Example ) .

Examples of quasi-experimental designs include:

  • One-Group Posttest Only Design
  • Static-Group Comparison Design
  • One-Group Pretest-Posttest Design
  • Separate-Sample Pretest-Posttest Design

What is an experimental design?

An experimental design is a randomized study design used to evaluate the effect of an intervention. In its simplest form, the participants will be randomly divided into 2 groups:

  • A treatment group: where participants receive the new intervention which effect we want to study.
  • A control or comparison group: where participants do not receive any intervention at all (or receive some standard intervention).

Randomization ensures that each participant has the same chance of receiving the intervention. Its objective is to equalize the 2 groups, and therefore, any observed difference in the study outcome afterwards will only be attributed to the intervention – i.e. it removes confounding.

(for more information, I recommend my other article: Purpose and Limitations of Random Assignment ).

Examples of experimental designs include:

  • Posttest-Only Control Group Design
  • Pretest-Posttest Control Group Design
  • Solomon Four-Group Design
  • Matched Pairs Design
  • Randomized Block Design

When to choose an experimental design over a quasi-experimental design?

Although many statistical techniques can be used to deal with confounding in a quasi-experimental study, in practice, randomization is still the best tool we have to study causal relationships.

Another problem with quasi-experiments is the natural progression of the disease or the condition under study — When studying the effect of an intervention over time, one should consider natural changes because these can be mistaken with changes in outcome that are caused by the intervention. Having a well-chosen control group helps dealing with this issue.

So, if losing the element of randomness seems like an unwise step down in the hierarchy of evidence, why would we ever want to do it?

This is what we’re going to discuss next.

When to choose a quasi-experimental design over a true experiment?

The issue with randomness is that it cannot be always achievable.

So here are some cases where using a quasi-experimental design makes more sense than using an experimental one:

  • If being in one group is believed to be harmful for the participants , either because the intervention is harmful (ex. randomizing people to smoking), or the intervention has a questionable efficacy, or on the contrary it is believed to be so beneficial that it would be malevolent to put people in the control group (ex. randomizing people to receiving an operation).
  • In cases where interventions act on a group of people in a given location , it becomes difficult to adequately randomize subjects (ex. an intervention that reduces pollution in a given area).
  • When working with small sample sizes , as randomized controlled trials require a large sample size to account for heterogeneity among subjects (i.e. to evenly distribute confounding variables between the intervention and control groups).

Further reading

  • Statistical Software Popularity in 40,582 Research Papers
  • Checking the Popularity of 125 Statistical Tests and Models
  • Objectives of Epidemiology (With Examples)
  • 12 Famous Epidemiologists and Why

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Quasi-Experimental Research

Learning objectives.

  • Explain what quasi-experimental research is and distinguish it clearly from both experimental and correlational research.
  • Describe three different types of quasi-experimental research designs (nonequivalent groups, pretest-posttest, and interrupted time series) and identify examples of each one.

The prefix  quasi  means “resembling.” Thus quasi-experimental research is research that resembles experimental research but is not true experimental research. Although the independent variable is manipulated, participants are not randomly assigned to conditions or orders of conditions (Cook & Campbell, 1979) [1] . Because the independent variable is manipulated before the dependent variable is measured, quasi-experimental research eliminates the directionality problem. But because participants are not randomly assigned—making it likely that there are other differences between conditions—quasi-experimental research does not eliminate the problem of confounding variables. In terms of internal validity, therefore, quasi-experiments are generally somewhere between correlational studies and true experiments.

Quasi-experiments are most likely to be conducted in field settings in which random assignment is difficult or impossible. They are often conducted to evaluate the effectiveness of a treatment—perhaps a type of psychotherapy or an educational intervention. There are many different kinds of quasi-experiments, but we will discuss just a few of the most common ones here.

Nonequivalent Groups Design

Recall that when participants in a between-subjects experiment are randomly assigned to conditions, the resulting groups are likely to be quite similar. In fact, researchers consider them to be equivalent. When participants are not randomly assigned to conditions, however, the resulting groups are likely to be dissimilar in some ways. For this reason, researchers consider them to be nonequivalent. A  nonequivalent groups design , then, is a between-subjects design in which participants have not been randomly assigned to conditions.

Imagine, for example, a researcher who wants to evaluate a new method of teaching fractions to third graders. One way would be to conduct a study with a treatment group consisting of one class of third-grade students and a control group consisting of another class of third-grade students. This design would be a nonequivalent groups design because the students are not randomly assigned to classes by the researcher, which means there could be important differences between them. For example, the parents of higher achieving or more motivated students might have been more likely to request that their children be assigned to Ms. Williams’s class. Or the principal might have assigned the “troublemakers” to Mr. Jones’s class because he is a stronger disciplinarian. Of course, the teachers’ styles, and even the classroom environments, might be very different and might cause different levels of achievement or motivation among the students. If at the end of the study there was a difference in the two classes’ knowledge of fractions, it might have been caused by the difference between the teaching methods—but it might have been caused by any of these confounding variables.

Of course, researchers using a nonequivalent groups design can take steps to ensure that their groups are as similar as possible. In the present example, the researcher could try to select two classes at the same school, where the students in the two classes have similar scores on a standardized math test and the teachers are the same sex, are close in age, and have similar teaching styles. Taking such steps would increase the internal validity of the study because it would eliminate some of the most important confounding variables. But without true random assignment of the students to conditions, there remains the possibility of other important confounding variables that the researcher was not able to control.

Pretest-Posttest Design

In a  pretest-posttest design , the dependent variable is measured once before the treatment is implemented and once after it is implemented. Imagine, for example, a researcher who is interested in the effectiveness of an antidrug education program on elementary school students’ attitudes toward illegal drugs. The researcher could measure the attitudes of students at a particular elementary school during one week, implement the antidrug program during the next week, and finally, measure their attitudes again the following week. The pretest-posttest design is much like a within-subjects experiment in which each participant is tested first under the control condition and then under the treatment condition. It is unlike a within-subjects experiment, however, in that the order of conditions is not counterbalanced because it typically is not possible for a participant to be tested in the treatment condition first and then in an “untreated” control condition.

If the average posttest score is better than the average pretest score, then it makes sense to conclude that the treatment might be responsible for the improvement. Unfortunately, one often cannot conclude this with a high degree of certainty because there may be other explanations for why the posttest scores are better. One category of alternative explanations goes under the name of  history . Other things might have happened between the pretest and the posttest. Perhaps an antidrug program aired on television and many of the students watched it, or perhaps a celebrity died of a drug overdose and many of the students heard about it. Another category of alternative explanations goes under the name of  maturation . Participants might have changed between the pretest and the posttest in ways that they were going to anyway because they are growing and learning. If it were a yearlong program, participants might become less impulsive or better reasoners and this might be responsible for the change.

Another alternative explanation for a change in the dependent variable in a pretest-posttest design is  regression to the mean . This refers to the statistical fact that an individual who scores extremely on a variable on one occasion will tend to score less extremely on the next occasion. For example, a bowler with a long-term average of 150 who suddenly bowls a 220 will almost certainly score lower in the next game. Her score will “regress” toward her mean score of 150. Regression to the mean can be a problem when participants are selected for further study  because  of their extreme scores. Imagine, for example, that only students who scored especially low on a test of fractions are given a special training program and then retested. Regression to the mean all but guarantees that their scores will be higher even if the training program has no effect. A closely related concept—and an extremely important one in psychological research—is  spontaneous remission . This is the tendency for many medical and psychological problems to improve over time without any form of treatment. The common cold is a good example. If one were to measure symptom severity in 100 common cold sufferers today, give them a bowl of chicken soup every day, and then measure their symptom severity again in a week, they would probably be much improved. This does not mean that the chicken soup was responsible for the improvement, however, because they would have been much improved without any treatment at all. The same is true of many psychological problems. A group of severely depressed people today is likely to be less depressed on average in 6 months. In reviewing the results of several studies of treatments for depression, researchers Michael Posternak and Ivan Miller found that participants in waitlist control conditions improved an average of 10 to 15% before they received any treatment at all (Posternak & Miller, 2001) [2] . Thus one must generally be very cautious about inferring causality from pretest-posttest designs.

Does Psychotherapy Work?

Early studies on the effectiveness of psychotherapy tended to use pretest-posttest designs. In a classic 1952 article, researcher Hans Eysenck summarized the results of 24 such studies showing that about two thirds of patients improved between the pretest and the posttest (Eysenck, 1952) [3] . But Eysenck also compared these results with archival data from state hospital and insurance company records showing that similar patients recovered at about the same rate  without  receiving psychotherapy. This parallel suggested to Eysenck that the improvement that patients showed in the pretest-posttest studies might be no more than spontaneous remission. Note that Eysenck did not conclude that psychotherapy was ineffective. He merely concluded that there was no evidence that it was, and he wrote of “the necessity of properly planned and executed experimental studies into this important field” (p. 323). You can read the entire article here:

The Effects of Psychotherapy: An Evaluation

Fortunately, many other researchers took up Eysenck’s challenge, and by 1980 hundreds of experiments had been conducted in which participants were randomly assigned to treatment and control conditions, and the results were summarized in a classic book by Mary Lee Smith, Gene Glass, and Thomas Miller (Smith, Glass, & Miller, 1980) [4] . They found that overall psychotherapy was quite effective, with about 80% of treatment participants improving more than the average control participant. Subsequent research has focused more on the conditions under which different types of psychotherapy are more or less effective.

Interrupted Time Series Design

A variant of the pretest-posttest design is the  interrupted time-series design . A time series is a set of measurements taken at intervals over a period of time. For example, a manufacturing company might measure its workers’ productivity each week for a year. In an interrupted time series-design, a time series like this one is “interrupted” by a treatment. In one classic example, the treatment was the reduction of the work shifts in a factory from 10 hours to 8 hours (Cook & Campbell, 1979) [5] . Because productivity increased rather quickly after the shortening of the work shifts, and because it remained elevated for many months afterward, the researcher concluded that the shortening of the shifts caused the increase in productivity. Notice that the interrupted time-series design is like a pretest-posttest design in that it includes measurements of the dependent variable both before and after the treatment. It is unlike the pretest-posttest design, however, in that it includes multiple pretest and posttest measurements.

Figure 7.3 shows data from a hypothetical interrupted time-series study. The dependent variable is the number of student absences per week in a research methods course. The treatment is that the instructor begins publicly taking attendance each day so that students know that the instructor is aware of who is present and who is absent. The top panel of  Figure 7.3 shows how the data might look if this treatment worked. There is a consistently high number of absences before the treatment, and there is an immediate and sustained drop in absences after the treatment. The bottom panel of  Figure 7.3 shows how the data might look if this treatment did not work. On average, the number of absences after the treatment is about the same as the number before. This figure also illustrates an advantage of the interrupted time-series design over a simpler pretest-posttest design. If there had been only one measurement of absences before the treatment at Week 7 and one afterward at Week 8, then it would have looked as though the treatment were responsible for the reduction. The multiple measurements both before and after the treatment suggest that the reduction between Weeks 7 and 8 is nothing more than normal week-to-week variation.

Figure 7.3 A Hypothetical Interrupted Time-Series Design. The top panel shows data that suggest that the treatment caused a reduction in absences. The bottom panel shows data that suggest that it did not.

Combination Designs

A type of quasi-experimental design that is generally better than either the nonequivalent groups design or the pretest-posttest design is one that combines elements of both. There is a treatment group that is given a pretest, receives a treatment, and then is given a posttest. But at the same time there is a control group that is given a pretest, does  not  receive the treatment, and then is given a posttest. The question, then, is not simply whether participants who receive the treatment improve but whether they improve  more  than participants who do not receive the treatment.

Imagine, for example, that students in one school are given a pretest on their attitudes toward drugs, then are exposed to an antidrug program, and finally are given a posttest. Students in a similar school are given the pretest, not exposed to an antidrug program, and finally are given a posttest. Again, if students in the treatment condition become more negative toward drugs, this change in attitude could be an effect of the treatment, but it could also be a matter of history or maturation. If it really is an effect of the treatment, then students in the treatment condition should become more negative than students in the control condition. But if it is a matter of history (e.g., news of a celebrity drug overdose) or maturation (e.g., improved reasoning), then students in the two conditions would be likely to show similar amounts of change. This type of design does not completely eliminate the possibility of confounding variables, however. Something could occur at one of the schools but not the other (e.g., a student drug overdose), so students at the first school would be affected by it while students at the other school would not.

Finally, if participants in this kind of design are randomly assigned to conditions, it becomes a true experiment rather than a quasi experiment. In fact, it is the kind of experiment that Eysenck called for—and that has now been conducted many times—to demonstrate the effectiveness of psychotherapy.

Key Takeaways

  • Quasi-experimental research involves the manipulation of an independent variable without the random assignment of participants to conditions or orders of conditions. Among the important types are nonequivalent groups designs, pretest-posttest, and interrupted time-series designs.
  • Quasi-experimental research eliminates the directionality problem because it involves the manipulation of the independent variable. It does not eliminate the problem of confounding variables, however, because it does not involve random assignment to conditions. For these reasons, quasi-experimental research is generally higher in internal validity than correlational studies but lower than true experiments.
  • Practice: Imagine that two professors decide to test the effect of giving daily quizzes on student performance in a statistics course. They decide that Professor A will give quizzes but Professor B will not. They will then compare the performance of students in their two sections on a common final exam. List five other variables that might differ between the two sections that could affect the results.
  • regression to the mean
  • spontaneous remission
  • Cook, T. D., & Campbell, D. T. (1979). Quasi-experimentation: Design & analysis issues in field settings . Boston, MA: Houghton Mifflin. ↵
  • Posternak, M. A., & Miller, I. (2001). Untreated short-term course of major depression: A meta-analysis of studies using outcomes from studies using wait-list control groups. Journal of Affective Disorders, 66 , 139–146. ↵
  • Eysenck, H. J. (1952). The effects of psychotherapy: An evaluation. Journal of Consulting Psychology, 16 , 319–324. ↵
  • Smith, M. L., Glass, G. V., & Miller, T. I. (1980). The benefits of psychotherapy . Baltimore, MD: Johns Hopkins University Press. ↵

Research Methods in Psychology Copyright © 2015 by Paul C. Price, Rajiv Jhangiani, & I-Chant A. Chiang is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License , except where otherwise noted.

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COMMENTS

  1. Quasi-Experimental Design

    Revised on January 22, 2024. Like a true experiment, a quasi-experimental design aims to establish a cause-and-effect relationship between an independent and dependent variable. However, unlike a true experiment, a quasi-experiment does not rely on random assignment. Instead, subjects are assigned to groups based on non-random criteria.

  2. Quasi Experimental Design Overview & Examples

    In contrast, true experiments use random assignment to the treatment and control groups to control confounding variables, making them the gold standard for identifying cause-and-effect relationships.. Quasi-experimental research is a design that closely resembles experimental research but is different. The term "quasi" means "resembling," so you can think of it as a cousin to actual ...

  3. Quasi-experiment

    A quasi-experiment is an empirical interventional study used to estimate the causal impact of an intervention on target population without random assignment.Quasi-experimental research shares similarities with the traditional experimental design or randomized controlled trial, but it specifically lacks the element of random assignment to treatment or control.

  4. 7.3 Quasi-Experimental Research

    Key Takeaways. Quasi-experimental research involves the manipulation of an independent variable without the random assignment of participants to conditions or orders of conditions. Among the important types are nonequivalent groups designs, pretest-posttest, and interrupted time-series designs.

  5. Selecting and Improving Quasi-Experimental Designs in Effectiveness and

    RCTs can also involve random assignment of groups (e.g., clinics, worksites or communities) to intervention and control arms, but a large number of groups are required in order to realize the full benefits of randomization. ... Quasi-experimental designs (QEDs), which first gained prominence in social science research , are increasingly being ...

  6. Quasi-Experimental Designs for Causal Inference

    But under certain conditions quasi-experimental designs that lack random assignment can also be as credible as RCTs (Shadish, Cook, & Campbell, 2002). This article discusses four of the strongest quasi-experimental designs for identifying causal effects: regression discontinuity design, instrumental variable design, matching and propensity ...

  7. Experimental and Quasi-Experimental Methods

    The two key designs that help researchers address whether a program or treatment causes an outcome are the experimental design, which uses random assignment to groups or programs, and quasi-experimental designs, which do not use random assignment (see Shadish et al. 2002; Bell 2010; Trochim 2006). These two methods are important to consider in ...

  8. Quasi-experimental study designs series—paper 5: a checklist for

    Credible quasi-experimental approaches are based on assignment to treatment and control that is not controlled by the investigators, and the term can be applied to different assignment rules; allocation to treatment and control is by definition not randomized, although some are based on identifying a source of variation in an exposure of ...

  9. Quasi-Experiment: Understand What It Is, Types & Examples

    Quasi-experimental research designs have gained significant recognition in the scientific community due to their unique ability to study cause-and-effect relationships in real-world settings. Unlike true experiments, quasi-experiment lack random assignment of participants to groups, making them more practical and ethical in certain situations.

  10. Quasi-Experimental Research Design

    No random assignment: Quasi-experimental designs do not require random assignment, which can be difficult or impossible in some cases, such as when studying the effects of a natural disaster. This means that researchers can still make causal inferences, although they must use statistical techniques to control for potential confounding variables

  11. Quasi-Experimental Design

    Quasi-Experimental Design. Quasi-Experimental Design is a unique research methodology because it is characterized by what is lacks. For example, Abraham & MacDonald (2011) state: ... It differs from experimental research because either there is no control group, no random selection, no random assignment, and/or no active manipulation. ...

  12. Quasi-Experimental Research

    Key Takeaways. Quasi-experimental research involves the manipulation of an independent variable without the random assignment of participants to conditions or orders of conditions. Among the important types are nonequivalent groups designs, pretest-posttest, and interrupted time-series designs.

  13. 8.2 Quasi-experimental and pre-experimental designs

    Pre-experimental designs - a variation of experimental design that lacks the rigor of experiments and is often used before a true experiment is conducted. Quasi-experimental design - designs lack random assignment to experimental and control groups. Static group design - uses an experimental group and a comparison group, without random ...

  14. (PDF) Experimental and quasi-experimental designs

    Random Assignment: Participants in experimental research are typically randomly assigned to different groups to ensure that each group is similar at the outset of the study.

  15. Experiments and Quasi-Experiments

    Often, however, it is not possible or practical to control all the key factors, so it becomes necessary to implement a quasi-experimental research design. Similarities between true and quasi-experiments: ... Random assignment neutralizes factors other than the independent and dependent variables, making it possible to directly infer cause and ...

  16. Experimental and Quasi-Experimental Designs in Implementation Research

    Other implementation science questions are more suited to quasi-experimental designs, which are intended to estimate the effect of an intervention in the absence of randomization. ... and second, random assignment of subjects. This corresponds to the definition of randomized experiments originally championed by Fisher (1925). From this ...

  17. An Introduction to Quasi-Experimental Design

    Quasi-experimental design (QED) is a research design method that's useful when regular experimental conditions are impractical or unethical. ... as it's more difficult to account for all confounding variables without using random assignment The necessary data required for research potentially being inaccurate, outdated, or difficult to ...

  18. 12.2: Pre-experimental and quasi-experimental design

    Quasi-experimental designs are similar to true experiments, but they lack random assignment to experimental and control groups. The most basic of these quasi-experimental designs is the nonequivalent comparison groups design (Rubin & Babbie, 2017). [1] The nonequivalent comparison group design looks a lot like the classic experimental design ...

  19. Quasi-Experimental Design: Types, Examples, Pros, and Cons

    See why leading organizations rely on MasterClass for learning & development. A quasi-experimental design can be a great option when ethical or practical concerns make true experiments impossible, but the research methodology does have its drawbacks. Learn all the ins and outs of a quasi-experimental design.

  20. The Use and Interpretation of Quasi-Experimental Studies in Medical

    Quasi-experimental study designs, often described as nonrandomized, pre-post intervention studies, are common in the medical informatics literature. Yet little has been written about the benefits and limitations of the quasi-experimental approach as applied to informatics studies. ... The lack of random assignment is the major weakness of the ...

  21. Experimental vs Quasi-Experimental Design: Which to Choose?

    A quasi-experimental design is a non-randomized study design used to evaluate the effect of an intervention. The intervention can be a training program, a policy change or a medical treatment. Unlike a true experiment, in a quasi-experimental study the choice of who gets the intervention and who doesn't is not randomized.

  22. Quasi-Experimental Research

    Key Takeaways. Quasi-experimental research involves the manipulation of an independent variable without the random assignment of participants to conditions or orders of conditions. Among the important types are nonequivalent groups designs, pretest-posttest, and interrupted time-series designs.