research questions for medical students

Explore the Best Medical and Health Research Topics Ideas

Table of contents

• 1 How to Choose Medical Research Paper Topics
• 2 New Medical Research Paper Topics
• 3 Medical Research Topics for College Students
• 4 Controversial Medical Topics for Research Paper
• 5 Health Research Topics
• 6 Medicine Research Topics
• 7 Healthcare Research Topics
• 8 Public Health Research Topics
• 9 Mental Health Research Paper Topics
• 10 Anatomy Research Topics
• 11 Biomedical Research Topics
• 12 Bioethics Research Topics
• 13 Cancer Research Topics
• 14 Clinical Research Topics
• 15 Critical Care Research Topics
• 16 Pediatric Research Topics
• 17 Dental Research Topics Ideas
• 18 Dermatology Research Topics
• 19 Primary Care Research Topics
• 20 Pharmaceutical Research Topics
• 21 Medical Anthropology Research Topics
• 22 Paramedic Research Paper Topics
• 23 Surgery Research Topics
• 24 Radiology Research Paper Topics
• 25 Anatomy and Physiology Research Paper Topics
• 26 Healthcare Management Research Paper Topics
• 27 Medical Ethics Research Paper Topics
• 28 Conclusion

In such a complex and broad field as medicine, writing an original and compelling research paper is a daunting task. From investigating public care concerns to cancer treatment studies, each student decides where his interests lie. Our goal is to help students find new angles to study and focus on relevant topics. With our resources, you can write an engaging and rigorous paper.

How to Choose Medical Research Paper Topics

Choosing good research paper topics is often more challenging than the writing process itself. You need to select a captivating subject matter that will grab the reader’s attention, showcase your knowledge of a specific field, help you progress in your studies, and perhaps even inspire future research.

To accomplish that, you need to start with brainstorming, followed by thorough research. Here are some great tips to follow:

• Pick an interesting topic – The key is to pick something that you find interesting, and yet make sure it’s not too general or too narrow. It should allow you to delve deep into the subject matter and show that you’re a professional who is ready to take on a challenge when it comes to your chosen field of medicine.
• Narrow down your focus – Once you have a list of potential topics, sift through recent medical research papers to get up-to-date with the latest trends, developments, and issues in medicine and healthcare. Check out textbooks, news articles, and other relevant sources for more information related to your potential topics. If a particular condition or disease interests you (perhaps something that drew you to a career in medicine), there’s your cue for narrowing down your topic.
• Pinpoint the “why,” “how,” and “what” – Whether you are looking into nutrition research paper topics , controversial medical topics, nursing research topics, or anything in-between, ask yourself why each of them is important. How could they contribute to the available medical studies, if any? What new information could they bring to improve the future of medicine? Asking these questions will help you pick the right medical research paper topic that suits you and helps you move forward and reach your aspirations.

To help you on that quest, we’ve compiled a list of topics that you could use or that might inspire you to come up with something unique. Let’s dive in.

New Medical Research Paper Topics

Are you interested in the newest and most interesting developments in medicine? We put hours of effort into identifying the current trends in health research so we could provide you with these examples of topics. Whether you hire a research paper writing service for students or write a paper by yourself, you need an appealing topic to focus on.

• Epidemics versus pandemics
• Child health care
• Medical humanitarian missions in the developing world
• Homoeopathic medicines – the placebo effect
• Virus infections – causes and treatment
• Is medical research on animals ethical
• Vaccination – dangers versus benefits
• Artificial tissues and organs
• Rare genetic diseases
• Brain injuries

Medical Research Topics for College Students

You don’t know where to start with your medical research paper? There are so many things you could write about that the greatest challenge is to narrow them down. This is why we decided to help.

• Antibiotics treatments
• Chronic diseases
• Palliative treatment
• Battling Alzheimer’s disease
• How modern lifestyle affects public health
• Professional diseases
• Sleep disorders
• Changes in physical and mental health due to aging
• Eating disorders
• Terminal diseases

Controversial Medical Topics for Research Paper

In healthcare, new discoveries can change people’s lives in the blink of an eye. This is also the reason why there are so many controversial topics in medicine, which involve anything from religion to ethics or social responsibility. Read on to discover our top controversial research topics.

• Implementing food standards
• Gluten allergy
• Assisted suicide for terminal patients
• Testing vaccines on animals – ethical concerns
• Moral responsibilities regarding cloning
• Marijuana legalization for medical purposes
• Abortion – medical approaches
• Vegan diets – benefits and dangers
• Increased life expectancy: a burden on the healthcare system?
• Circumcision effects

Health Research Topics

Students conducting health research struggle with finding good ideas related to their medical interests. If you want to write interesting college papers, you can select a good topic for our list.

• How environmental changes affect human health
• Deafness: communication disorders
• Household air pollution
• Diabetes – a public danger
• Coronaviruses
• Oral health assessment
• Tobacco and alcohol control
• Diseases caused by lack of physical exercise
• How urban pollution affects respiratory diseases
• Healthy diets

Medicine Research Topics

Regardless of the requirements in your research assignment, you can write about something that is both engaging and useful in your future career. Choose a topic from below.

• Causes for the increasing cancer cases
• Insulin resistance
• How terrorism affects mental health
• AIDS/HIV – latest developments
• Treating pregnant women versus non-pregnant women
• Latest innovations in medical instruments
• Genetic engineering
• Successful treatment of mental diseases
• Is autism a disease
• Natural coma versus artificial coma

Healthcare Research Topics

Healthcare research includes political and social aspects, besides medical. For college students who want to explore how medicine is affected by society’s values or principles, we provide examples of topics for papers. Select yours from the list below.

• Government investment in healthcare services in the EU versus the USA
• Inequalities in healthcare assistance and services
• Electronic health records systems – pros and cons
• Can asylums treat mental issues
• Health care for prison inmates
• Equipment for improving treatment of AIDS
• Correlation between economic development and health care services across countries
• Impact of smoking on organs
• Heart attacks – causes and effects
• Breast cancer – recent developments

Public Health Research Topics

For current examples of public health topics, browse our list. We provide only original, researchable examples for which you can easily find supporting data and evidence.

• Public versus private hospitals
• Health care professionals – management principles
• Surgery failures – who is responsible
• What legal responsibilities has the hospital administration
• Patient service quality in public versus private hospitals
• What benefits national health care systems have
• Estimated costs of cancer treatments
• Public health in developing countries
• Banning tobacco ads – importance for public health
• Government solutions to the anti-vaccine’s movement

Mental Health Research Paper Topics

Mental health is one of the most complex areas of medicine, where things are never as clear as with other medical issues. This increases the research potential of the field with plenty of topics left for debate.

• Causes of anxiety disorders
• Bulimia versus anorexia
• Childhood trauma
• Mental health public policies
• Postpartum Depression
• Posttraumatic Stress Disorder
• Seasonal Affective Disorder
• Schizophrenia

Anatomy Research Topics

Anatomy covers everything about the human body and how it works. If you find that intriguing and want to pay for medical research paper, start by selecting a topic.

• Chemotherapy: how it affects the body
• Thyroid glands – functions in the body
• Human endocrine system
• Heart diseases
• How does the human muscular system develop
• Lymphatic system – importance
• Investigating genetic diseases
• Digestive system

Biomedical Research Topics

Biology and medicine often work together. For the newest changes in the biomedical field, check our topics.

• Alzheimer’s disease – paths for treatment
• Vaccines and drug development in the treatment of Ebola
• Antibiotic resistance
• Biological effects caused by aging
• Air pollution effects on health
• Infectious disease past versus present
• Regenerative medicine
• Biomedical diagnostics
• Biomedical technology

Bioethics Research Topics

A controversial area of medicine, bioethics is where you get the chance to add personal input to a research topic and come up with new insights. You could consider these subjects.

• Organ donation
• Alternative or complementary medicine
• Assisted suicide or the right to die
• Artificial insemination or surrogacy
• Chemical and biological warfare
• Contraception
• Environmental bioethics
• In Vitro fertilization

Cancer Research Topics

Are you writing a paper related to cancer causes, diagnosis, treatment or effects? Look below for a hot topic that it’s easy to research and important for medical advance.

• Ability of immune system cells to fight cancer
• Computational oncology
• Metastasis affected by drug resistance
• Stem cells – applications for cancer treatment
• Tumor microenvironment
• Obesity and age in cancer occurrence
• Early cancer detection – benefits
• Artificial intelligence predicting cancer
• Hematologic malignancies
• Pathogen-related cancers

Clinical Research Topics

Learn more about clinical medicine by conducting more in-depth research. We prepared for you a list of relevant issues to touch upon.

• Ethical concerns regarding research on human subjects
• Subject recruitment
• Budget preparation
• Human subject protection
• Clinical trials – financial support
• Clinical practices for health professionals
• Using vulnerable populations in clinical research
• Quality assurance in clinical research
• Academic clinical trials versus clinical trials units
• Data collection and management

Critical Care Research Topics

Critical care is a key area in medical studies. Explore these topics in your research paper to gain more valuable knowledge in this field. You can also get in contact with nursing research paper writers .

• Obesity and asthma – clinical manifestations
• Chronic obstructive pulmonary disease
• Rhythm analysis for cardiac arrest
• Traumatic brain injury – fluid resuscitation
• Hydrocortisone for multiple trauma patients
• Care and nutrition for critically ill adults
• Diagnosis of hypersensitivity pneumonitis
• Coma and sedation scales
• Artificial airways suctioning
• Arterial puncture and arterial line

Pediatric Research Topics

Any topic that refers to health care for children, pregnant women, mothers, and adolescents goes under pediatric care.

• Attention deficit hyperactivity disorder (ADHD)
• Congenital heart disease in newborns
• Adolescent medicine
• Neonatal medicine
• Rare diseases in children and teenagers
• Obesity and weight fluctuations
• Behavioral sleep problems in children
• Children with anemia

Dental Research Topics Ideas

Choose a topic on oral health or dental care from this list of the most interesting topics in the field.

• How smoking affects oral health
• Children’s risk for dental caries
• Dental anxiety
• Types of dental materials – new advances
• Bad breath bacteria
• How diabetes affects oral health
• Oral cancer
• Dental pain – types, causes
• Dental implants
• Oral health-related quality of life

Dermatology Research Topics

Find the best research topic for your dermatology paper among our examples.

• Atopic dermatitis
• Contact dermatitis
• Epidemiology behind uncommon skin disorders
• Cutaneous aging
• Risk factors of melanoma skin cancer
• Acne versus rosacea
• Genetic testing for skin conditions
• Effects of cosmetic agents on skin health
• Improving skin barrier with pharmaceutical agents
• Skin manifestations of autoimmune disorders

Primary Care Research Topics

Write a primary care paper that can demonstrate your research skills and interest in powerful scientific findings.

• Primary care for vulnerable/uninsured populations
• Interpersonal continuity in care treatment
• How primary care contributes to health systems
• Primary care delivery models
• Developments in family medicine
• Occupational/environmental health
• Pharmacotherapy approaches
• Formal allergy testing
• Oral contraception side effects
• Dietary or behavioral interventions for obesity management

Pharmaceutical Research Topics

Pharma students who need paper topics can use one from our list. We include all things related to pharmacy life.

• Drugs that can treat cancer
• Drug excretion
• Elimination rate constant
• Inflammatory stress drug treatment
• Aspirin poising
• Ibuprofen – dangers versus benefits
• Toxicodynamics
• Opioid use disorder
• Pharmacotherapy for schizophrenia
• Ketamine in depression treatment

Medical Anthropology Research Topics

Medical anthropology unites different areas of human knowledge. Find powerful ideas for a paper below.

• Cultural contexts regarding reproductive health
• Women sexuality
• Anthropological aspects of health care
• Contributions of social sciences to public health
• Euthanasia and medical ethics across cultures
• Health-related behavior in adults across cultures
• Transcultural nursing
• Forensic psychiatry
• Symptoms of Celiac Disease – a disease with no symptoms
• Nursing ethics

Paramedic Research Paper Topics

Topics for paramedic research must be based on evidence, data, statistics, or practical experience. Just like ours.

• Trends and statistics in EMS
• Disaster medicine
• Mass casualties
• Pandemics and epidemics
• Infection control
• Basic versus advanced life support
• Scene safety in EMS
• Shock management
• Motor vehicle accidents

Surgery Research Topics

Discover all the intricacies of surgeries that save lives by writing about our topics.

• Medical malpractice and legal issues
• Methicillin-resistant Staphylococcus aureus
• Pain management
• Perioperative nursing
• Wound management
• Colorectal cancer surgery
• Breast cancer surgery
• Minimally invasive surgeries
• Vascular disease

Radiology Research Paper Topics

Find a radiology topic related to your academic interests to write a successful paper.

• Using MRI to diagnose hepatic focal lesions
• Multidetector computer tomography
• Ultrasound elastography in breast cancer
• Assessing traumatic spinal cord injuries with MRI diffusion tensor imaging
• Sonographic imaging to detect male infertility
• Role of tomography in diagnosing cancer
• Brain tumor surgery with magnetic resonance imaging
• Bacterial meningitis imaging

Anatomy and Physiology Research Paper Topics

Any ideas for a medical research paper? We have included the most important topics for an anatomy and physiology paper.

• What role has the endocrine system
• Staphylococcus aureus
• Environmental factors that affect development of human muscular system
• What role has the lymphatic system
• An investigation of genetic diseases
• Explaining the aging process
• The digestive tract
• Effects of stress on cells and muscles
• Evolution of the human nervous system
• What role has the cardiovascular system

Healthcare Management Research Paper Topics

There are numerous topics you could write about when it comes to healthcare management. There’s a wide range of options to pick, from infrastructure, staff, and financial management to HR and patient management. Here are some of the top healthcare management research paper options.

• Medical talent acquisition and retention
• Best methods for enhancing preventative care measures
• The role of telemedicine in reinventing healthcare management
• Patient care and the ability to pay for healthcare
• Mid-level healthcare providers in the emergency department
• The opioid crisis: policies and programs
• Urgent care and walk-in clinics
• Hospital emergency management plan during an epidemic
• Hospital records management and patient privacy
• Financial crises: challenges and opportunities

Medical Ethics Research Paper Topics

Medical ethics is a field that opens the door to numerous compelling topics for research papers. Here are some of the most appealing ones you could tackle.

• Clinical research on humans
• Vaccines and immunization
• Religious beliefs in healthcare
• Euthanasia and physician-assisted suicide
• Ethical issues across cultures
• Amniocentesis or prenatal birth defect testing
• Medical malpractice and going back to work
• Racial and ethnic preferences and perceptions in organ donations
• Racial and ethnic disparities in healthcare
• Ethical concerns of AI in healthcare

If you need further assistance with your medical research paper, PapersOwl is here for you. Our expert writers can provide you with top-notch research and help you write an impressive paper. Contact us anytime, pick your writer, tell them more about your topic, and get a unique, plagiarism-free research paper with impeccable grammar and formatting.

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Research Topics & Ideas: Healthcare

100+ Healthcare Research Topic Ideas To Fast-Track Your Project

Finding and choosing a strong research topic is the critical first step when it comes to crafting a high-quality dissertation, thesis or research project. If you’ve landed on this post, chances are you’re looking for a healthcare-related research topic , but aren’t sure where to start. Here, we’ll explore a variety of healthcare-related research ideas and topic thought-starters across a range of healthcare fields, including allopathic and alternative medicine, dentistry, physical therapy, optometry, pharmacology and public health.

NB – This is just the start…

The topic ideation and evaluation process has multiple steps . In this post, we’ll kickstart the process by sharing some research topic ideas within the healthcare domain. This is the starting point, but to develop a well-defined research topic, you’ll need to identify a clear and convincing research gap , along with a well-justified plan of action to fill that gap.

If you’re new to the oftentimes perplexing world of research, or if this is your first time undertaking a formal academic research project, be sure to check out our free dissertation mini-course. In it, we cover the process of writing a dissertation or thesis from start to end. Be sure to also sign up for our free webinar that explores how to find a high-quality research topic.

Overview: Healthcare Research Topics

• Allopathic medicine
• Alternative /complementary medicine
• Veterinary medicine
• Physical therapy/ rehab
• Optometry and ophthalmology
• Pharmacy and pharmacology
• Public health
• Examples of healthcare-related dissertations

Allopathic (Conventional) Medicine

• The effectiveness of telemedicine in remote elderly patient care
• The impact of stress on the immune system of cancer patients
• The effects of a plant-based diet on chronic diseases such as diabetes
• The use of AI in early cancer diagnosis and treatment
• The role of the gut microbiome in mental health conditions such as depression and anxiety
• The efficacy of mindfulness meditation in reducing chronic pain: A systematic review
• The benefits and drawbacks of electronic health records in a developing country
• The effects of environmental pollution on breast milk quality
• The use of personalized medicine in treating genetic disorders
• The impact of social determinants of health on chronic diseases in Asia
• The role of high-intensity interval training in improving cardiovascular health
• The efficacy of using probiotics for gut health in pregnant women
• The impact of poor sleep on the treatment of chronic illnesses
• The role of inflammation in the development of chronic diseases such as lupus
• The effectiveness of physiotherapy in pain control post-surgery

Topics & Ideas: Alternative Medicine

• The benefits of herbal medicine in treating young asthma patients
• The use of acupuncture in treating infertility in women over 40 years of age
• The effectiveness of homoeopathy in treating mental health disorders: A systematic review
• The role of aromatherapy in reducing stress and anxiety post-surgery
• The impact of mindfulness meditation on reducing high blood pressure
• The use of chiropractic therapy in treating back pain of pregnant women
• The efficacy of traditional Chinese medicine such as Shun-Qi-Tong-Xie (SQTX) in treating digestive disorders in China
• The impact of yoga on physical and mental health in adolescents
• The benefits of hydrotherapy in treating musculoskeletal disorders such as tendinitis
• The role of Reiki in promoting healing and relaxation post birth
• The effectiveness of naturopathy in treating skin conditions such as eczema
• The use of deep tissue massage therapy in reducing chronic pain in amputees
• The impact of tai chi on the treatment of anxiety and depression
• The benefits of reflexology in treating stress, anxiety and chronic fatigue
• The role of acupuncture in the prophylactic management of headaches and migraines

Topics & Ideas: Dentistry

• The impact of sugar consumption on the oral health of infants
• The use of digital dentistry in improving patient care: A systematic review
• The efficacy of orthodontic treatments in correcting bite problems in adults
• The role of dental hygiene in preventing gum disease in patients with dental bridges
• The impact of smoking on oral health and tobacco cessation support from UK dentists
• The benefits of dental implants in restoring missing teeth in adolescents
• The use of lasers in dental procedures such as root canals
• The efficacy of root canal treatment using high-frequency electric pulses in saving infected teeth
• The role of fluoride in promoting remineralization and slowing down demineralization
• The impact of stress-induced reflux on oral health
• The benefits of dental crowns in restoring damaged teeth in elderly patients
• The use of sedation dentistry in managing dental anxiety in children
• The efficacy of teeth whitening treatments in improving dental aesthetics in patients with braces
• The role of orthodontic appliances in improving well-being
• The impact of periodontal disease on overall health and chronic illnesses

Tops & Ideas: Veterinary Medicine

• The impact of nutrition on broiler chicken production
• The role of vaccines in disease prevention in horses
• The importance of parasite control in animal health in piggeries
• The impact of animal behaviour on welfare in the dairy industry
• The effects of environmental pollution on the health of cattle
• The role of veterinary technology such as MRI in animal care
• The importance of pain management in post-surgery health outcomes
• The impact of genetics on animal health and disease in layer chickens
• The effectiveness of alternative therapies in veterinary medicine: A systematic review
• The role of veterinary medicine in public health: A case study of the COVID-19 pandemic
• The impact of climate change on animal health and infectious diseases in animals
• The importance of animal welfare in veterinary medicine and sustainable agriculture
• The effects of the human-animal bond on canine health
• The role of veterinary medicine in conservation efforts: A case study of Rhinoceros poaching in Africa
• The impact of veterinary research of new vaccines on animal health

Topics & Ideas: Physical Therapy/Rehab

• The efficacy of aquatic therapy in improving joint mobility and strength in polio patients
• The impact of telerehabilitation on patient outcomes in Germany
• The effect of kinesiotaping on reducing knee pain and improving function in individuals with chronic pain
• A comparison of manual therapy and yoga exercise therapy in the management of low back pain
• The use of wearable technology in physical rehabilitation and the impact on patient adherence to a rehabilitation plan
• The impact of mindfulness-based interventions in physical therapy in adolescents
• The effects of resistance training on individuals with Parkinson’s disease
• The role of hydrotherapy in the management of fibromyalgia
• The impact of cognitive-behavioural therapy in physical rehabilitation for individuals with chronic pain
• The use of virtual reality in physical rehabilitation of sports injuries
• The effects of electrical stimulation on muscle function and strength in athletes
• The role of physical therapy in the management of stroke recovery: A systematic review
• The impact of pilates on mental health in individuals with depression
• The use of thermal modalities in physical therapy and its effectiveness in reducing pain and inflammation
• The effect of strength training on balance and gait in elderly patients

Topics & Ideas: Optometry & Opthalmology

• The impact of screen time on the vision and ocular health of children under the age of 5
• The effects of blue light exposure from digital devices on ocular health
• The role of dietary interventions, such as the intake of whole grains, in the management of age-related macular degeneration
• The use of telemedicine in optometry and ophthalmology in the UK
• The impact of myopia control interventions on African American children’s vision
• The use of contact lenses in the management of dry eye syndrome: different treatment options
• The effects of visual rehabilitation in individuals with traumatic brain injury
• The role of low vision rehabilitation in individuals with age-related vision loss: challenges and solutions
• The impact of environmental air pollution on ocular health
• The effectiveness of orthokeratology in myopia control compared to contact lenses
• The role of dietary supplements, such as omega-3 fatty acids, in ocular health
• The effects of ultraviolet radiation exposure from tanning beds on ocular health
• The impact of computer vision syndrome on long-term visual function
• The use of novel diagnostic tools in optometry and ophthalmology in developing countries
• The effects of virtual reality on visual perception and ocular health: an examination of dry eye syndrome and neurologic symptoms

Topics & Ideas: Pharmacy & Pharmacology

• The impact of medication adherence on patient outcomes in cystic fibrosis
• The use of personalized medicine in the management of chronic diseases such as Alzheimer’s disease
• The effects of pharmacogenomics on drug response and toxicity in cancer patients
• The role of pharmacists in the management of chronic pain in primary care
• The impact of drug-drug interactions on patient mental health outcomes
• The use of telepharmacy in healthcare: Present status and future potential
• The effects of herbal and dietary supplements on drug efficacy and toxicity
• The role of pharmacists in the management of type 1 diabetes
• The impact of medication errors on patient outcomes and satisfaction
• The use of technology in medication management in the USA
• The effects of smoking on drug metabolism and pharmacokinetics: A case study of clozapine
• Leveraging the role of pharmacists in preventing and managing opioid use disorder
• The impact of the opioid epidemic on public health in a developing country
• The use of biosimilars in the management of the skin condition psoriasis
• The effects of the Affordable Care Act on medication utilization and patient outcomes in African Americans

Topics & Ideas: Public Health

• The impact of the built environment and urbanisation on physical activity and obesity
• The effects of food insecurity on health outcomes in Zimbabwe
• The role of community-based participatory research in addressing health disparities
• The impact of social determinants of health, such as racism, on population health
• The effects of heat waves on public health
• The role of telehealth in addressing healthcare access and equity in South America
• The impact of gun violence on public health in South Africa
• The effects of chlorofluorocarbons air pollution on respiratory health
• The role of public health interventions in reducing health disparities in the USA
• The impact of the United States Affordable Care Act on access to healthcare and health outcomes
• The effects of water insecurity on health outcomes in the Middle East
• The role of community health workers in addressing healthcare access and equity in low-income countries
• The impact of mass incarceration on public health and behavioural health of a community
• The effects of floods on public health and healthcare systems
• The role of social media in public health communication and behaviour change in adolescents

Examples: Healthcare Dissertation & Theses

While the ideas we’ve presented above are a decent starting point for finding a healthcare-related research topic, they are fairly generic and non-specific. So, it helps to look at actual dissertations and theses to see how this all comes together.

Below, we’ve included a selection of research projects from various healthcare-related degree programs to help refine your thinking. These are actual dissertations and theses, written as part of Master’s and PhD-level programs, so they can provide some useful insight as to what a research topic looks like in practice.

• Improving Follow-Up Care for Homeless Populations in North County San Diego (Sanchez, 2021)
• On the Incentives of Medicare’s Hospital Reimbursement and an Examination of Exchangeability (Elzinga, 2016)
• Managing the healthcare crisis: the career narratives of nurses (Krueger, 2021)
• Methods for preventing central line-associated bloodstream infection in pediatric haematology-oncology patients: A systematic literature review (Balkan, 2020)
• Farms in Healthcare: Enhancing Knowledge, Sharing, and Collaboration (Garramone, 2019)
• When machine learning meets healthcare: towards knowledge incorporation in multimodal healthcare analytics (Yuan, 2020)
• Integrated behavioural healthcare: The future of rural mental health (Fox, 2019)
• Healthcare service use patterns among autistic adults: A systematic review with narrative synthesis (Gilmore, 2021)
• Mindfulness-Based Interventions: Combatting Burnout and Compassionate Fatigue among Mental Health Caregivers (Lundquist, 2022)
• Transgender and gender-diverse people’s perceptions of gender-inclusive healthcare access and associated hope for the future (Wille, 2021)
• Efficient Neural Network Synthesis and Its Application in Smart Healthcare (Hassantabar, 2022)
• The Experience of Female Veterans and Health-Seeking Behaviors (Switzer, 2022)
• Machine learning applications towards risk prediction and cost forecasting in healthcare (Singh, 2022)
• Does Variation in the Nursing Home Inspection Process Explain Disparity in Regulatory Outcomes? (Fox, 2020)

Looking at these titles, you can probably pick up that the research topics here are quite specific and narrowly-focused , compared to the generic ones presented earlier. This is an important thing to keep in mind as you develop your own research topic. That is to say, to create a top-notch research topic, you must be precise and target a specific context with specific variables of interest . In other words, you need to identify a clear, well-justified research gap.

Need more help?

If you’re still feeling a bit unsure about how to find a research topic for your healthcare dissertation or thesis, check out Topic Kickstarter service below.

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15 Comments

I need topics that will match the Msc program am running in healthcare research please

Hello Mabel,

I can help you with a good topic, kindly provide your email let’s have a good discussion on this.

Can you provide some research topics and ideas on Immunology?

Thank you to create new knowledge on research problem verse research topic

Help on problem statement on teen pregnancy

This post might be useful: https://gradcoach.com/research-problem-statement/

can you provide me with a research topic on healthcare related topics to a qqi level 5 student

Please can someone help me with research topics in public health ?

Hello I have requirement of Health related latest research issue/topics for my social media speeches. If possible pls share health issues , diagnosis, treatment.

I would like a topic thought around first-line support for Gender-Based Violence for survivors or one related to prevention of Gender-Based Violence

Please can I be helped with a master’s research topic in either chemical pathology or hematology or immunology? thanks

Can u please provide me with a research topic on occupational health and safety at the health sector

Good day kindly help provide me with Ph.D. Public health topics on Reproductive and Maternal Health, interventional studies on Health Education

may you assist me with a good easy healthcare administration study topic

May you assist me in finding a research topic on nutrition,physical activity and obesity. On the impact on children

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300+ Health Related Research Topics For Medical Students(2023)

In the world of academia and healthcare, finding the right health-related research topics is essential. Whether you are a medical student, a college student, or a seasoned researcher, the choice of your research topic greatly impacts the quality and relevance of your work. This blog, health related research topics, is your guide to selecting the perfect subject for your research.

In this post, we will share 5 invaluable tips to help you pick suitable health-related research topics. Additionally, we will outline the crucial elements that every health-related research paper should incorporate.

Furthermore, we’ve compiled a comprehensive list of 300+ health-related research topics for medical students in 2023. These include categories like mental health, public health, nutrition, chronic diseases, healthcare policy, and more. We also offer guidance on selecting the right topic to ensure your research is engaging and meaningful.

So, whether you are delving into mental health, investigating environmental factors, or exploring global health concerns, health-related research topics will assist you in making informed and impactful choices for your research journey, even within the hardest medical specialties .

What Is Health Research?

Table of Contents

Health research is like detective work to understand how our bodies work and how to keep them healthy. It’s like asking questions and finding answers about things like sickness, medicine, and how to live better. Scientists and doctors do health research to learn new ways to treat illnesses, like finding better medicines or discovering new ways to prevent diseases.

Health research is a puzzle, where scientists collect information, do experiments, and study many people to find out what makes us healthy or sick. They want to find clues and put them together to help us stay well and live longer. So, health research is like a quest to learn more about our bodies and find ways to make them work their best, keeping us happy and strong.

5 Useful Tips For Choosing Health Related Research Topics

Here are some useful tips for choosing health related research topics: 

Tip 1: Follow Your Interests

When picking a health research topic, it’s a good idea to choose something you’re curious and excited about. If you’re interested in a subject, you’ll enjoy learning more about it, and you’ll be motivated to do your best. So, think about what aspects of health catch your attention and explore those areas for your research.

Tip 2: Consider Relevance

Your research topic should be meaningful and have real-world importance. Think about how your research can contribute to solving health problems or improving people’s well-being. Topics that are relevant and can make a positive impact on health and healthcare are usually more valuable.

Tip 3: Check Available Resources

Before deciding on a research topic, make sure you have access to the necessary resources, like books, articles, or equipment. It’s important that you can find the information and tools you need to conduct your research effectively.

Tip 4: Keep It Manageable

Select a research topic that you can handle within the available time and resources. It’s better to choose a more focused and manageable topic rather than something too broad or complex. This way, you can delve deep into the subject and produce meaningful results.

Tip 5: Seek Guidance

Don’t hesitate to ask for guidance from teachers, professors, or experts in the field. They can help you refine your research topic, provide valuable insights, and suggest improvements. Seeking advice can make your research journey smoother and more successful.

Important Elements That Must Be Present In A Health Related Research Paper

Here are some important elements that must be present in a health related research paper: 

1. Clear Title and Introduction

A good health research paper needs a clear title that tells people what it’s about. The introduction should explain why the research is important and what the paper will discuss. It’s like the map that shows the way.

2. Methods and Data

You should describe how you did your research and the data you collected. This helps others understand how you found your information. It’s like showing your work in math so that others can check it.

3. Results and Conclusions

After doing your research, you need to show what you discovered. Share the results and what they mean. Conclusions tell people what you found out and why it’s important. It’s like the “So what?” part of your paper.

4. Citations and References

When you use other people’s ideas or words, you need to give them credit. Citations and references show where you got your information. It’s like saying, “I learned this from here.”

5. Clear Language and Organization

Make sure your paper is easy to read and well-organized. Use clear and simple language so that everyone can understand. Organize your paper logically, with a beginning, middle, and end, like a good story. This makes your research paper more effective and useful.

In this section, we will discuss 300+ health related research topics for medical students(2023): 

Health Related Research Topics

• How living choices affect health and how long people live.
• Ways to make it easier for people in underserved areas to get medical care.
• The role of DNA in determining susceptibility to different diseases.
• There are differences in health between race and ethnic groups and between socioeconomic groups.
• Checking how well health education programs encourage people to behave in a healthy way.
• The effects that stress has on the body and mind.
• Looking at the pros and cons of different vaccine plans.
• The link between how well you sleep and your general health.
• The use of technology to make health care better.
• How cultural beliefs and habits affect how people seek health care.

Mental Health Related Research Topics

• Identifying the factors contributing to the rise in mental health disorders among adolescents.
• Examining the effectiveness of different therapeutic approaches for treating depression and anxiety.
• How social media can hurt your mental health and self-esteem.
• We are looking into the link between traumatic events in youth and mental health problems later in life.
•  Stigma and racism in mental health care, and how they make people less healthy.
•  Ways to lower the suicide rate among people who are at high risk.
•  Exercise and other forms of physical action can help your mental health.
•  The link between using drugs and having mental health problems.
•  Mental health support for frontline healthcare workers during and after the COVID-19 pandemic.
•  Exploring the potential of digital mental health interventions and apps.

Health Related Research Topics For College Students

• The impact of college stress on physical and mental health.
•  Assessing the effectiveness of college mental health services.
•  The role of peer influence on college students’ health behaviors.
•  Nutrition and dietary habits among college students.
•  Substance use and abuse on college campuses.
•  Investigating the prevalence of sleep disorders among college students.
•  Exploring sexual health awareness and behaviors among college students.
•  Evaluating the relationship between academic performance and overall health.
•  The influence of social media on college students’ health perceptions and behaviors.
•  Ideas for getting people on college grounds to be more active and eat better.

Public Health Related Research Topics

• Evaluating the impact of public health campaigns on smoking cessation.
•  The effectiveness of vaccination mandates in preventing disease outbreaks.
•  Looking into the link between the health of the people in cities and the quality of the air.
•  Strategies for addressing the opioid epidemic through public health initiatives.
•  The role of public health surveillance in early disease detection and response.
•  Assessing the impact of food labeling on consumer choices and nutrition.
•  Looking at how well public health measures work to lower the number of overweight and obese kids.
•  The importance of water quality in maintaining public health.
•  This paper examines various strategies aimed at enhancing mother and child health outcomes in emerging nations.
•  Addressing the mental health crisis through public health interventions.

Mental Disorder Research Topics

• The mental health effects of social isolation, with a particular focus on the COVID-19 pandemic.
•  Exploring the relationship between mental health and creative expression.
•  Cultural differences influence the way in which mental health disorders are perceived and treated.
•  The use of mindfulness and meditation techniques in managing mental health.
•  Investigating the mental health challenges faced by LGBTQ+ individuals.
•  Examining the role of nutrition and dietary habits in mood disorders.
•  The influence of childhood experiences on adult mental health.
•  Innovative approaches to reducing the stigma surrounding mental health.
•  Mental health support for veterans and active-duty military personnel.
•  The relation between sleep disorders and mental health.

Nutrition and Diet-Related Research Topics

• The impact of dietary patterns (e.g., Mediterranean, ketogenic) on health outcomes.
•  Investigating the role of gut microbiota in digestion and overall health.
•  The effects of food labeling and nutritional education on dietary choices.
•  The correlation between chronic disease prevention and nutrition.
•  Assessing the nutritional needs of different age groups (children, adults, elderly).
•  Exploring the benefits and drawbacks of various diet fads (e.g., intermittent fasting, veganism).
•  The role of nutrition in managing obesity and weight-related health issues.
•  Studying nutrition and mental wellness.
•   Impact of food insecure areas on population health and diet.
•  Strategies for promoting healthy eating in schools and workplaces.

Chronic Disease Research Topics

• The contribution of inflammation to the progression and development of chronic diseases.
•  Evaluating the effectiveness of lifestyle modifications in managing chronic conditions.
•  The impact of chronic stress on various health conditions.
•  Investigating disparities in the management and treatment of chronic diseases among different populations.
•  Exploring the genetics of chronic diseases and potential gene therapies.
•  The impact that environmental factors, including pollution, have on the prevalence of chronic diseases.
•  Assessing the long-term health consequences of childhood obesity.
•  Strategies for improving the quality of life for individuals living with chronic diseases.
•  The importance of maintaining a healthy level of physical activity and exercise for both the prevention and treatment of chronic illnesses.
•  Investigating innovative treatments and therapies for chronic diseases, such as gene editing and personalized medicine.

Healthcare Policy and Access Research Topics

• Assessing how the Affordable Care Act affects healthcare access and outcomes.
•  Telehealth’s impact on rural healthcare access.
•  Investigating the cost-effectiveness of various healthcare payment models (e.g., single-payer, private insurance).
•  Assessing healthcare disparities among different racial and socioeconomic groups.
•  The influence of political ideologies on healthcare policy and access.
•  Healthcare professional shortage solutions, including nurses and doctors.
•  The impact of malpractice reform on healthcare quality and access.
•  Examining the role of pharmaceutical pricing and regulation in healthcare access.
•  The use of technology in streamlining healthcare administration and improving access.
•  Exploring the intersection of healthcare policy, ethics, and patient rights.

Environmental Health Research Topics

• The impact of climate change on public health, including increased heat-related illnesses and vector-borne diseases.
•  Studying air pollution’s effects on the cardiovascular and respiratory systems.
•  Assessing the health consequences of exposure to environmental toxins and pollutants.
•  Exploring the role of green spaces and urban planning in promoting public health.
•  The impact of water quality and sanitation on community health.
•  Strategies for minimizing the health risks linked with natural catastrophes and extreme weather events.
•  Investigating the health implications of food and water security in vulnerable populations.
•  The influence of environmental justice on health disparities.
•  Evaluating the benefits of renewable energy sources in reducing air pollution and promoting health.
•  The role of public policy in addressing environmental health concerns.

Infectious Disease Research Topics

• Tracking the evolution and spread of infectious diseases, including COVID-19.
•  Investigating the effectiveness of vaccination campaigns in preventing outbreaks.
•  Antimicrobial resistance and strategies to combat it.
•  Assessing the role of vector-borne diseases in global health, such as malaria and Zika virus.
•  The impact of travel and globalization on the spread of infectious diseases.
•  Strategies for early detection and containment of emerging infectious diseases.
•  The role of hygiene and sanitation in reducing infectious disease transmission.
•  Investigating the cultural factors that influence infectious disease prevention and treatment.
•  The use of technology in disease surveillance and response.
• Examining the ethical and legal considerations in managing infectious disease outbreaks.

Women’s Health Research Topics

• Exploring the gender-specific health issues faced by women, such as reproductive health and menopause.
• Investigating the impact of hormonal contraception on women’s health.
• Assessing the barriers to accessing quality maternal healthcare in low-income countries.
• The role of gender-based violence in women’s mental and physical health.
• Strategies for promoting women’s sexual health and reproductive rights.
• Exploring the relationship between breast cancer and genetics.
• The influence of body image and societal pressures on women’s mental health.
• Investigating healthcare disparities among different groups of women, including racial and ethnic disparities.
• Strategies for improving access to women’s healthcare services, including family planning and prenatal care.
• The use of telemedicine and technology to address women’s health needs, especially in remote areas.

Children’s Health Research Topics

• The impact of early childhood nutrition on long-term health and development.
• Environmental toxin exposure and child health.
• Assessing the role of parenting styles in children’s mental and emotional well-being.
• Strategies for preventing and managing childhood obesity.
• The influence of media and technology on children’s physical and mental health.
• Exploring the challenges faced by children with chronic illnesses and disabilities.
• The relevance of early child mental wellness and developmental condition intervention.
• Investigating the role of schools in promoting children’s health and well-being.
• Strategies for addressing child healthcare disparities, including access to vaccines and preventive care.
• Adverse childhood experiences and adult health.

Aging and Gerontology Research Topics

• Investigating the factors contributing to healthy aging and longevity.
• Assessing the impact of dementia and Alzheimer’s disease on elderly individuals and their families.
• Strategies for improving elder care services and addressing the aging population’s healthcare needs.
• Exploring the social isolation and mental health challenges faced by the elderly.
• The importance of nutrition and exercise in old age.
• Investigating the impact of age-related chronic diseases, such as arthritis and osteoporosis.
• Assessing the financial and ethical aspects of end-of-life care for the elderly.
• Strategies for promoting intergenerational relationships and support networks.
• The influence of cultural differences on aging and health outcomes.
• Exploring technology and innovation in elder care, including assistive devices and telemedicine.

Health Technology and Innovation Research Topics

• The impact of telemedicine and virtual health platforms on patient care and outcomes.
• Investigating the use of wearable health technology in monitoring and managing chronic conditions.
• Assessing the ethical and privacy considerations of health data collection through technology.
• Investigating medical diagnoses and treatment with AI and ML.
• The role of robotics in healthcare, including surgical procedures and elder care.
• Investigating the use of 3D printing in healthcare, such as prosthetics and medical devices.
• The influence of mobile health apps on patient engagement and self-care.
• Strategies for implementing electronic health records (EHRs) and interoperability.
• The impact of precision medicine and genomics on personalized healthcare.
• Exploring the future of healthcare delivery through telehealth, remote monitoring, and AI-driven diagnostics.

Global Health Research Topics

• Investigating the challenges of global health equity and healthcare access in low- and middle-income countries.
• Assessing the effectiveness of international health organizations in addressing global health crises.
• Resource-limited mother and child health strategies.
• Exploring the impact of infectious diseases in global health, including tuberculosis and HIV/AIDS.
• The role of clean water and sanitation in improving global health outcomes.
• Investigating the social determinants of health in different global regions.
• Assessing the impact of humanitarian aid and disaster relief efforts on public health.
• Strategies for combating malnutrition and food insecurity in developing countries.
• The influence of climate change on global health, including the spread of vector-borne diseases.
• Exploring innovative approaches to global health, such as community health workers and telemedicine initiatives.
• Exploring the artificial intelligence and machine learning in medical treatment.

Health Disparities and Equity Research Topics

• The impact of socioeconomic status on healthcare access and health outcomes.
• Strategies to decrease racial and ethnic disparities in maternal and child health.
• LGBTQ+ healthcare disparities and interventions for equitable care.
• Health disparities among rural and urban populations in developed and developing countries.
• Cultural competence in healthcare and its role in reducing disparities.
• The intersection of gender, race, and socioeconomic status in health disparities.
• Addressing health disparities in the elderly population.
• The role of discrimination in perpetuating health inequities.
• Strategies to improve healthcare access for individuals with disabilities.
• The impact of COVID-19 on health disparities and lessons learned for future pandemics.

Cancer Research Topics

• Advancements in precision medicine for personalized cancer treatment.
• Immunotherapy breakthroughs in cancer treatment.
• Environmental factors and cancer risk: A comprehensive review.
• The role of genomics in understanding cancer susceptibility.
• Cancer treatment and survivorship, as well as quality of life following cancer therapy.
• The economics of cancer treatment and its impact on patients.
• Cancer prevention and early detection strategies in underserved communities.
• Palliative care and end-of-life decisions in cancer patients.
• Emerging trends in cancer epidemiology and global burden.
• Ethical considerations in cancer clinical trials and research.

Pharmaceutical Research Topics

• Repurposing existing medications in order to address uncommon illnesses.
• The impact of nanotechnology in drug delivery and targeting.
• Pharmacogenomics and personalized medicine: Current status and future prospects.
• Challenges and opportunities in developing vaccines for emerging infectious diseases.
• Quality control and safety in the pharmaceutical manufacturing process.
• Drug pricing and access: A global perspective.
• Green chemistry approaches in sustainable pharmaceutical development.
• The part that artificial intelligence plays in the search for new drugs and their development.
• Biopharmaceuticals and the future of protein-based therapies.
• Regulatory challenges in ensuring drug safety and efficacy.

Epidemiology Research Topics

• Emerging infectious diseases and global preparedness.
• The COVID-19 pandemic will have long-term effect on the health of the general population.
• Social determinants of health and their impact on disease prevalence.
• Environmental epidemiology and the study of health effects of pollution.
• Big data and its role in modern epidemiological research.
• Spatial epidemiology and the study of disease clusters.
• Epidemiological aspects of non-communicable diseases (NCDs) like diabetes and obesity.
• Genetic epidemiology and the study of hereditary diseases.
• Epidemiological methods for studying mental health disorders.
• Epidemiology of zoonotic diseases and their prevention.

Alternative and Complementary Medicine Research Topics

• Efficacy and safety of herbal remedies in complementary medicine.
• Mind-body interventions and their role in managing chronic pain.
• Acupuncture and its potential in the treatment of various conditions.
• Integrating traditional and complementary medicine into mainstream healthcare.
• Yoga and meditation for stress reduction and mental health.
• Biofield therapies and their impact on well-being.
• Ayurvedic medicine and its modern applications in health and wellness.
• Chiropractic care and its use in musculoskeletal health.
• Ethical considerations in the practice and regulation of alternative medicine.
• Integrating traditional Chinese medicine into Western healthcare systems.

Occupational Health and Safety Research Topics

• Occupational hazards in healthcare settings and strategies for prevention.
• The impact of remote work on occupational health and well-being.
• Ergonomics and its role in preventing workplace injuries.
• Occupational exposure to hazardous chemicals and long-term health effects.
• Mental health in the office: Stress, burnout, and interventions.
• Occupational safety in the construction industry: Recent developments.
• Role of technology in enhancing workplace safety.
• Occupational health disparities among different industries and occupations.
• The economics of workplace safety and the cost-benefit analysis.
• Business impacts of OSHA regulations.

Addiction and Substance Abuse Research Topics

• The opioid epidemic: Current status and future strategies.
• Dual diagnosis: Co-occurring mental health disorders and substance abuse.
• Harm reduction approaches in addiction treatment.
• The role of family and social support in addiction recovery.
• Behavioral addictions: Understanding and treating non-substance-related addictions.
• Novel pharmacotherapies for addiction treatment.
• The impact of COVID-19 on substance abuse and addiction.
• Substance abuse prevention programs in schools and communities.
• Stigmatization of addiction and its impact on treatment-seeking behavior.
• Substance abuse in the elderly population: Unique challenges and solutions.

Biomedical Research Topics

• Recent advancements in gene editing technologies (e.g., CRISPR-Cas9).
• Regenerative medicine and tissue engineering for organ replacement.
• Bioinformatics and its role in analyzing large-scale biological data.
• Stem cell research and its important applications in regenerative medicine.
• Biomarker discovery for early disease detection and monitoring.
• Precision medicine and its potential to transform healthcare.
• The microbiome and its impacts on human health and disease.
• Aging-related research and interventions for healthy aging.
• Neurodegenerative diseases and potential therapeutic approaches.
• Biomedical ethics in the age of cutting-edge research.

Maternal and Child Health Research Topics

• The influence of the mother’s nutrition on the development and health of the fetus.
• Maternal mental health and its positive effects on child development.
• Preterm birth prevention and interventions for at-risk pregnancies.
• Neonatal screening and early diagnosis of congenital diseases.
• Breastfeeding promotion and support for new mothers.
• Pediatric immunization programs and vaccine hesitancy.
• Child obesity prevention and intervention strategies.
• Maternal and child health in low-resource and conflict-affected areas.
• Maternal mortality reduction and improving access to obstetric care.
• Adverse childhood experiences (ACEs) and their long-term health consequences.

Mental Health Stigma Research Topics

• Understanding the origins and perpetuation of mental health stigma.
• Media and pop culture’s impact on mental disease views.
• Reducing stigma in the workplace and promoting mental health support.
• Stigma associated with specific mental health conditions (e.g., schizophrenia, bipolar disorder).
• Intersectionality and how it influences mental health stigma.
• Anti-stigma campaigns and their effectiveness in changing public attitudes.
• Stigma in online communities and the role of social media in shaping opinions.
• Cultural and cross-cultural perspectives on mental health stigma.
• The impact of self-stigma on individuals seeking mental health treatment.
• Legislative and policy efforts to combat mental health stigma.

Health Education and Promotion Research Topics

• Health literacy and its impact on informed decision-making.
• Promoting healthy behaviors in schools and educational settings.
• Social marketing campaigns for health behavior change.
• Community-based health promotion programs in underserved areas.
• The role of technology and social media in health education.
• Tailoring health messages to diverse populations and cultural sensitivity.
• The use of behavioral economics in health promotion strategies.
• Investigating the effectiveness of school-based sex education programs.
• Health education for the elderly population: Challenges and solutions.
• Promoting mental health awareness and resilience through education.

Healthcare Quality and Patient Safety Research Topics

• Patient-centered care and its impact on healthcare quality.
• Reducing medical errors and negative events in healthcare settings.
• Continuous quality improvement in healthcare organizations.
• The role of healthcare accreditation in ensuring quality and safety.
• Patient engagement and shared decision-making in healthcare.
• Electronic health records and patient safety.
• The ethics of telling patients and families about medical blunders.
• Medication safety and preventing adverse drug events.
• Cultural competence in healthcare and its effect on patient safety.
• Disaster preparedness and response in healthcare settings.

Health Informatics and Data Analytics Research Topics

• Big data analytics in healthcare for predictive modeling.
• Artificial intelligence in medical image analysis and diagnostics.
• Health information exchange and interoperability challenges.
• Electronic health record (EHR) usability and user satisfaction.
• Patient data privacy and security in health informatics.
• Telemedicine and its impact on healthcare delivery and data management.
• Real-time monitoring and data analytics for disease outbreaks.
• Health informatics applications in personalized medicine.
• Natural language processing for clinical notes and text analysis.
• The role of data analyticsin enhancing healthcare quality and outcomes.

Neurological Disorders Research Topics

• Neuroinflammation in neurodegenerative diseases (e.g., Alzheimer’s and Parkinson’s).
• Stroke prevention and rehabilitation strategies.
• Advances in brain imaging techniques for diagnosing neurological disorders.
• Pediatric neurological disorders: Diagnosis and intervention.
• Neurogenetics and the role of genetics in neurological conditions.
• Traumatic brain injury: Long-term effects and rehabilitation.
• Neurorehabilitation and quality of life improvement in patients with neurological disorders.
• Neurological consequences of long COVID and post-viral syndromes.
• The gut-brain connection and its implications for neurological health.
• Ethical considerations in neurological research and treatment.

Bioethics in Health Research Topics

• Informed consent and its challenges in clinical trials and research.
• Ethical considerations in human genome editing and gene therapy.
• Allocation of healthcare resources and the principles of distributive justice.
• The ethics of organ transplantation and organ trafficking.
• End-of-life decision-making, including physician-assisted suicide.
• Ethical issues in the use of Artficial intelligence in healthcare decision-making.
• Research involving vulnerable populations: Balancing benefits and risks.
• Ethical considerations in global health research and disparities.
• Ethical implications of emerging biotechnologies, such as CRISPR-Cas9.
• Autonomy and decision-making capacity in healthcare ethics.

Read More 

• Biology Research Topics
• Neuroscience Research Topics

Points To Be Remembered While Selecting Health Related Research Topics

When selecting a health-related research topic, there are several important considerations to keep in mind to ensure your research is meaningful and effective. Here are 7 key points to remember:

• Interest and Passion: Choose a topic that is according to your interests you, as your enthusiasm will fuel your research.
• Relevance: Ensure your topic addresses a real health issue or concern that can make a positive impact.
• Resources Availability: Confirm that you have access to the necessary materials and information for your research.
• Manageability: Pick a topic that is not too broad, ensuring it’s something you can investigate thoroughly.
• Guidance: Seek advice from experts or mentors to refine your topic and receive valuable insights.
• Ethical Considerations : Always consider the ethical implications of your research and ensure it complies with ethical guidelines.
• Feasibility: Ensure that the research can be completed within the available time and resources.

In the ever-evolving landscape of health research, selecting the right topic is the foundation for meaningful contributions. This blog has provided a roadmap for choosing health-related research topics, emphasizing the importance of personal interest, relevance, available resources, manageability, and expert guidance. Additionally, it has offered 300+ research topics across various domains, including mental health, public health, nutrition, chronic diseases, healthcare policy, and more. 

In addition, with these insights, researchers, students, and healthcare professionals can embark on journeys that not only align with their passions but also address critical healthcare challenges. By making informed choices, we can collectively advance the frontiers of health and well-being.

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300+ Medical Research Topics & Ideas for Students to Choose

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Every healthcare research begins with a single step. But in the world of academia, that step often involves hours of pondering over the perfect medical research topic idea. When it comes to medical research paper topics, there's a seemingly limitless array of options that stretches as far as the mind can wander. The potential of this field is exciting but can also be challenging to explore.

To help you narrow down your choices and research effectively, our research paper writer team compiled a list of interesting medical research topics. Whether you want to write about the latest developments in public health or explore the implications of emerging technologies, this blog won't disappoint you.

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Medical research topics are the ideas or concepts related to health and medicine. They often explore new treatments, developments in diagnosis, prevention of illnesses, or even the effects of lifestyle choices. The scope of topics in medicine is vast and can include such aspects:

• Clinical medicine
• Biomedical research
• Public health
• Mental health research topics
• Medical technology
• Health services research.

Your choice should stem from your interests and existing gaps that need to be filled.

Choosing the right medical topic for a research paper is like finding a golden ticket to a successful study. Here's what makes a medicine research idea a real showstopper:

• Engagement Research should be engaging and relevant to the audience.
• Precision Good ideas are always specific, so that you can focus your research on a particular area without being too vague.
• Authenticity A good topic needs to address an issue that hasn't been studied before.
• Feasibility Ensure your topic is realistic. Good research topics in healthcare should fit within your budget, timeframe, and available resources.
• Relevance Winning medical research project topics should address current and pressing issues in healthcare.

Selecting the best idea out of multiple medicine research topics can be a daunting task, especially when you have so many fields to explore. Here are a few steps that will help you settle on a theme:

• Brainstorm and come up with as many ideas as possible.
• Narrow down your list by considering factors such as your interest and resources.
• Look for current tendencies in healthcare research.
• Consult your supervisor or a librarian to verify the pertinence of the topic that you have chosen.
• Make sure your topic is specific enough to be addressed within the scope of your project.

Once you come up with a fitting medical research topic, consider half the battle won. But in case you have difficulties creating an original title, our online paper writers prepared a list of research ideas for medical students you might like.

Below we collected various medical topics to research in your study. From groundbreaking technologies to emerging diseases, there are countless avenues to investigate. If you're on the hunt for a compelling topic, here are some of the top medical researches topics capturing attention in 2023:

• Effective strategies for medical talent acquisition and retention.
• The best methods for enhancing preventative care measures in contemporary medicine.
• The role and impact of telemedicine in reinventing healthcare management.
• Implications of artificial intelligence on diagnostics and treatment plans.
• The rising threat of antimicrobial resistance and its effects on global health.
• The link between environmental changes and public health outcomes.
• Complexities of vaccine development and human immune responses.
• Health inequities: Causes, consequences, and potential solutions.
• New treatment approaches for neurodegenerative disorders.
• A multidisciplinary approach to tackling obesity and metabolic disorders.

Navigating countless medical topics for research papers can often feel like a journey through a labyrinth. Here are some intriguing ideas that could ignite your curiosity and fuel your research:

• How does climate change impact human health?
• Communication disorders: A closer look at deafness.
• The hidden dangers of household air pollution.
• The escalating threat of diabetes in the public sphere.
• Coronavirus and how it changed the landscape of public health.
• Assessing oral health: Beyond the basics.
• Tobacco and alcohol control: A public health perspective.
• Health implications of a sedentary lifestyle.
• Urban pollution and its impact on respiratory diseases
• The role of healthy diets in disease prevention.
• Exploring the mental health impact of social media.
• How do cultural factors influence public health initiatives?
• The role of nutrition in managing chronic diseases.
• Investigating the genetics of neurodegenerative disorders.
• What are some ethical considerations in gene editing?

Exploring the depths of medicine can be an exciting experience. You'll discover that every issue has a plethora of complexities and avenues to investigate. Here are some interesting medical topics for research paper that could pique your curiosity:

• The influence of lifestyle changes on cardiovascular health.
• What are some psychological impacts of chronic illness?
• Connection between gut health and mental well-being.
• Evaluating the effectiveness of telehealth during the pandemic.
• How do genetic factors influence addiction susceptibility?
• Autoimmune diseases and their peculiarities.
• How does stress affect immune function?
• What are some health impacts of sleep disorders?
• The link between socioeconomic status and health outcomes.
• Exploring innovations in pain management.
• Analyzing implications of artificial intelligence in healthcare.
• Effect of climate change on infectious disease patterns.
• A look into advancements in cancer immunotherapy.
• Exploring the potential of stem cells in treating degenerative diseases.
• How does diet influence the progression of Alzheimer's disease?

You may be looking for simple research topics in medicine that won't take too much time and effort to complete. Explore these straightforward ideas that could make your paper stand out:

• Importance of proper sanitation in healthcare settings.
• Exploring the role of patient support groups in disease management.
• Analyzing the efficacy of physical therapy interventions.
• What are the cost-effective interventions for healthcare delivery?
• What are some effects of new pharmaceuticals?
• What are some health consequences of air pollution?
• How does meditation improve outcomes in mental health care?
• Evaluating the role of nutritionists in weight loss management.
• An analysis of trends and patterns in emerging diseases.
• Exploring alternative medicines in contemporary healthcare.
• Examining the impact of healthcare policies on public health outcomes.
• Can the use of herbs provide an effective remedy for certain illnesses?
• How does mental health stigma affect access to treatment?
• Drug abuse: Causes, consequences and prevention strategies.
• What are some psychological issues associated with chronic illnesses?

When it comes to choosing medical research topics, you need something that's striking and meaningful. Hover over these ideas to spot the fitting idea for your medical research:

• Exploring new strategies for treating neurological disorders.
• What is the role of medical ethics in modern healthcare?
• What are some implications of genetics in personalized healthcare?
• Exploring innovations in non-invasive diagnosis techniques.
• Effect of temperature on patient outcomes in critical care.
• How does air pollution influence healthcare costs?
• How do changes in lifestyle lead to better health outcomes?
• Implications of electronic health records for patient privacy.
• Role of nutritionists in disease prevention.
• How technology is being used to revolutionize healthcare?
• What are the most effective treatments for rare diseases?
• How have medical imaging techniques advanced over the years?
• Investigating potential treatments for autism spectrum disorder.
• Exploring innovative approaches to mental healthcare delivery.
• What are some implications of artificial intelligence in medical diagnosis?

Navigate through the most contentious research topics in health and explore the debate that surrounds them. Consider these thought-provoking ideas and medical controversial topics:

• Ethical implications of genetic engineering.
• Euthanasia and physician-assisted suicide - where do we draw the line?
• Are mandatory vaccinations an infringement on personal freedom or a public health necessity?
• Evaluating medical and legal perspectives on the use of medical marijuana.
• Ethical concerns around animal testing in medical research.
• How do we navigate the morality and legality of abortion?
• Should the criminal justice system focus more on mental health treatment than punishment?
• Is stem cell research a moral dilemma or a medical breakthrough?
• Ethical considerations in organ trading and transplantation.
• Who should shoulder the burden of healthcare costs?
• Is access to healthcare a privilege or a human right?
• Ethics of using placebo in clinical trials – is it justified?
• Assessing the role of Big Pharma in healthcare - is it a necessary evil?
• Can genetic screening lead to discrimination, despite its benefits?
• Should modern medicine take precedence over traditional medicine, or is there room for both?

Discover the latest studies in healthcare and explore the newest topics for a medical research paper. Below we prepared some cutting-edge topics for you to consider:

• Can gene-editing technologies such as CRISPR transform the treatment of genetic disorders?
• How does microbiome therapy potentially influence the treatment of autoimmune diseases?
• Exploring the advent of personalized medicine through genomics and precision diagnostics.
• How is virtual reality altering the landscape of surgical training and rehabilitation therapies?
• How can telehealth improve healthcare access, particularly in remote and underserved areas?
• The role of nanotechnology in developing more efficient drug delivery systems.
• What are some implications of the rising antimicrobial resistance, and where does the future of antibiotics lie?
• How are advances in non-invasive treatments changing the face of chronic disease management?
• Is precision oncology the future of cancer treatment?
• What are some implications and potential of regenerative medicine and tissue engineering?
• Can advancements in wearable technology revolutionize personal health monitoring?
• How are gut microbiota affecting our understanding and treatment of metabolic disorders?
• What role do nanobots play in medical treatments?
• Can big data analytics be used to improve the accuracy of medical diagnosis?

There are multiple medical topics to write about. But as a student, you're probably looking for something more specific. For your convenience, we divided the titles by academic levels. So, roll up your sleeves and get ready to explore these health topics for research that your professor will surely appreciate.

For students who want to investigate different aspect of healthcare, we provided these examples of ideas. Browse through these medical research topics for high school students to spot the most relevant theme:

• How does the human immune system work?
• Vaccinations as an essential tool in preventing diseases.
• A basic overview of genetic disorders.
• What makes viruses unique?
• How does the body fight off bacterial infections?
• The impact of lifestyle factors on heart health.
• Diabetes: Types, causes, and prevention strategies.
• The importance of mental health in the medical field.
• Skin health: Understanding common skin conditions like acne and eczema.
• Structure and function of the human heart.
• Role of antibiotics and how do they fight bacteria?
• Journey of a pill: From ingestion to action.
• What happens in an allergic reaction?
• How does physical exercise impact the body and mind?
• Racial disparities in healthcare and access to treatment.

At the college level, you may be asked to write a research paper on a complex issue. We prepared these health research topics for college students to help you get started on your assignment:

• Exploring the implications of health insurance reform.
• Genomic sequencing in the early detection of genetic disorders.
• Machine learning in diagnostic imaging: A new era in radiology?
• The role of diet in the prevention and management of type 2 diabetes.
• Exploring the link between circadian rhythms and health disorders.
• The role of personalized medicine in cancer treatment.
• Development and use of prosthetics in physical rehabilitation.
• Understanding autoimmune diseases: The body fighting itself.
• Addressing health disparities through community-based interventions.
• Inflammation in the development of chronic diseases.
• The rise of antibiotic-resistant bacteria: Causes and implications.
• Innovations in drug delivery systems: From nanoparticles to smart pills.
• How can we address the opioid crisis in America?
• Investigating the use of mobile technology for delivering healthcare services.
• Exploring medical implications of 3D printing technology.

We've also provided some research topics for medical students grouped by specific subjects. Check them out and pick the one you find most captivating.

Pediatrics involves the care and health of children. As such, it is a broad field ripe with interesting medical topics. Given the unique physiology needs of these younger populations, pediatric research is crucial for understanding illnesses. Below you can find captivating research topics in pediatrics:

• Exploring the impact of nutrition on childhood development.
• Assessing the effects of screen time on adolescent mental health.
• Investigating genetic factors in pediatric cancers.
• The role of vaccinations in preventing common childhood illnesses.
• Strategies for managing childhood obesity.
• The impact of prenatal exposure to drugs and alcohol on infant health.
• Development and evaluation of therapies for Autism Spectrum Disorders.
• Understanding the rise of food allergies in children.
• Advances in the treatment of congenital heart defects.
• Exploring the causes and treatment strategies for pediatric asthma.
• The impact of environmental toxins on child health.
• Evaluation of therapeutic approaches for Attention Deficit Hyperactivity Disorder (ADHD).
• Implications of early life stress on mental health in adolescence.
• The role of gut microbiota in pediatric diseases.
• Understanding the genetic basis of rare childhood disorders.

Anatomy is the study of the organization and structure of the body. It encompasses many topics for medical research papers, from bones and organs to cell structures. Consider these ideas when writing your next anatomy paper:

• The role of genetics in bone fragility disorders.
• A comparative study of the skeletal systems across different species.
• The role and function of the lymphatic system in human health.
• Investigating complexities of the human brain's structure.
• Development and growth of human muscles.
• Impact of aging on bone health and structure.
• Exploring the intricate workings of the human cardiovascular system.
• Understanding structural changes in lungs in chronic respiratory diseases.
• The anatomical basis of speech and language development.
• Neuroanatomy of pain: Understanding pain pathways and mechanisms.
• Structural adaptations of the human body for athletic performance.
• Anatomy of the human eye and its role in vision.
• How does connective tissue support body structures?
• How does endocrine system impact hormone production?
• How does female anatomy change during pregnancy?

Medical anthropology looks at health and illness from a cultural perspective. It draws on expertise from across disciplines such as biology, psychology, and sociology to better understand how medical systems can work within different communities. If you’re interested in this field, use these ideas for med research topics:

• Investigating cultural beliefs and practices surrounding childbirth.
• Impact of socioeconomic status on health outcomes in different cultures.
• Understanding the role of traditional medicine in modern healthcare systems.
• An exploration of how cultural beliefs influence mental health perceptions.
• Effect of migration on health outcomes.
• The role of diet and nutrition in health from a cultural perspective.
• Cultural competence in healthcare delivery: Challenges and opportunities.
• Intersection of gender, culture, and health.
• Impact of societal norms and values on disease prevalence.
• Health disparities among indigenous populations.
• Role of social support networks in health and wellness across cultures.
• The impact of stigma on health outcomes in HIV/AIDS patients.
• The role of cultural anthropology in global health interventions.
• Ethnobotany and its implications for drug discovery.
• Understanding health practices in post-conflict societies.

Physiology studies how living organisms function. This branch covers a range of medicine topics and ideas you might like. Here are some suggestions for your next med paper in physiology:

• How does nervous system contribute to the perception of pain?
• What physiological changes are triggered by acute and chronic stress?
• How does regular exercise influence cardiovascular health and overall well-being?
• How do hormones influence our metabolic rate and energy utilization?
• A detailed study on physiological transformations during pregnancy and lactation.
• How does the process of aging affect the function and resilience of various organs?
• Exploring the role of homeostasis in maintaining the body's internal balance.
• What are the key physiological processes involved in the sleep cycle?
• Unraveling complexities of the human digestive system from ingestion to excretion.
• How does the renal system contribute to maintaining blood pressure?
• Physiological adaptations humans undergo when living at high altitudes.
• How does dehydration disrupt normal bodily functions?
• Implications of obesity on respiratory function and efficiency.
• How does the endocrine system orchestrate growth and development?
• Investigating the neurophysiological underpinnings of memory formation and retrieval.

From understanding skin conditions to exploring new procedures, dermatological research is a crucial part of improving skin health. Look through these medical research ideas centered around dermatology:

• Investigating the causes and treatments of acne in adolescents.
• Diet and the development of psoriasis.
• Understanding genetic factors involved in atopic dermatitis.
• Skin cancer: Risk factors, prevention, and treatment strategies.
• How do environmental factors cause skin aging?
• Exploring new treatments for hair loss.
• Understanding the correlation between stress and skin conditions.
• The role of the microbiome in skin health and disease.
• New approaches in the treatment of vitiligo.
• The impact of UV radiation on skin health.
• Exploring the pathophysiology of rosacea.
• The role of telemedicine in dermatology.
• Clinical advancements in the treatment of fungal skin infections.
• The correlation between skin health and mental health.
• Advances in cosmetic dermatology: Safety and effectiveness of new procedures.

Nursing is a versatile profession that covers many areas of health care. It’s also an ever-changing field, with new research and advancements being released all the time. Here are some topics for medical research paper focusing on nursing:

• The impact of nurse-patient communication on patient outcomes.
• Exploring the effects of nurse fatigue on job performance.
• How does nurse practitioner autonomy influence patient care?
• Importance of bedside manner in nursing.
• The role of technology in nursing practice.
• Understanding challenges associated with ethical decision-making in nursing.
• How does nurse burnout affect patient safety?
• Analyzing factors contributing to nurse retention and turnover rates.
• The effects of staffing ratios on nurse and patient satisfaction.
• Exploring the role of leadership in nursing practice.
• What are implications of nurse workload on healthcare outcomes?
• The impact of health policy on nursing education and practice.
• Ethical dilemmas faced by nurses in end-of-life care.
• How does culture affect perceptions of healthcare and nursing.
• What are some effects of managed care on nurse autonomy?

>> Read more: Nursing Research Paper Topics

Primary care is the first point of contact between patients and medical professionals. This branch is often overlooked, but it’s an important area of research that can improve health outcomes in communities around the world. Check out these interesting health topics to discuss in primary care:

• Exploring the impact of primary care physician shortages on health outcomes.
• How do socio-economic factors influence health outcomes in primary care?
• Strategies to improve patient adherence to treatment.
• What are some challenges and opportunities of providing mental health services?
• The role of primary care in managing chronic diseases.
• Evaluating the effectiveness of preventive measures in primary care.
• How does patient education influence health outcomes in primary care?
• The role of health technology in improving primary care delivery.
• What are some best practices for managing multimorbidity in primary care?
• Developing effective communication strategies for diverse patient populations in primary care.
• The impact of health policy changes on care delivery.
• How can primary care practices be adapted to meet the needs of an aging population?
• Assessing the effectiveness of integrated care models.
• The role of primary care in addressing health disparities.
• Strategies for improving patient satisfaction in primary care.

Public health is an important area of research - understanding how to improve health in communities and prevent illness and injury are crucial skills for medical professionals. Here are some medical related research topics that could kick-start your next project:

• What are the causes, implications and solutions to food insecurity?
• The role of public health in the management of infectious diseases.
• Assessing the effectiveness of smoking cessation programs.
• The role of public health initiatives in combating the obesity epidemic.
• What are some policy interventions that can improve public health?
• The impact of racism and discrimination on public health outcomes.
• Exploring new models for delivering mental health services in underserved communities.
• The impact of urbanization on public health outcomes.
• Evaluating the effectiveness of school-based health education programs.
• Strategies for managing public health crises during natural disasters.
• The implications of antibiotic resistance for public health.
• How can community engagement improve public health initiatives?
• The role of public health in the prevention and control of zoonotic diseases.
• What are the effects of environmental toxins on human health?
• How can mutual efforts reduce maternal and infant mortality rates?

>> View more: Public Health Research Topics

Mental health is an important area of research, as it affects so many people around the world. Here are some medical research paper ideas to get you started on your next mental health project:

• The effectiveness of cognitive-behavioral therapy in treating anxiety disorders.
• How does social media influence adolescents' mental health?
• Exploring the link between gut health and wellbeing.
• The role of mindfulness in managing stress and enhancing mental well-being.
• Understanding the genetic factors in schizophrenia.
• How can stigma associated with mental illness be reduced in society?
• How do traumatic events influence mental health?
• Potential art therapy application in emotional health treatment.
• The role of mental health in managing chronic diseases.
• The impact of the COVID-19 pandemic on global mental health.
• Understanding the correlation between sleep deprivation and emotional wellbeing.
• Strategies for improving mental health services in rural areas.
• How can nutrition benefit mental health?
• Exploring the effectiveness of peer support in mental health recovery.
• The benefits and challenges of telepsychiatry.

>> View more: Mental Health Research Paper Topics

Medical ethics is an important direction in healthcare research. Check these fascinating health topics to research for your next paper:

• Exploring moral implications of assisted suicide.
• How do ethical considerations come into play during organ transplantation?
• The ethical conundrum of maintaining patient confidentiality in the digital age.
• The integral role of informed consent in the physician-patient relationship.
• What ethical dilemmas arise from genetic testing and gene editing technologies?
• Ethical considerations of implementing artificial intelligence in healthcare.
• Is it ethical to use placebos in clinical trials?
• Balancing individual rights and public health in the context of a pandemic.
• Navigating ethical issues surrounding end-of-life care.
• Ethical challenges involved in the rationing of limited healthcare resources.
• What ethical considerations are necessary when conducting clinical research in low-resource settings?
• Ethical debate surrounding the use of animals for medical research.
• Ethical questions raised by advancements in reproductive technologies and rights.
• What are ethical implications of mandatory vaccination policies?
• Understanding ethical dilemmas associated with using health data for research.

Medical research is an important topic for many people. Below you can find more medical research topic ideas that didn't fall in any of categories offered above.

Health research paper topics are crucial to understanding the effects of trends and developments in the medical field. Here are some ideas to get you inspired:

• How does virtual reality change physical rehabilitation?
• Investigating the effects of pollution on respiratory health.
• The effectiveness of mindfulness-based interventions in mental health.
• The role of nutrition in managing cardiovascular diseases.
• Assessing health impacts of climate change.
• Evaluating the effectiveness of health education programs in schools.
• Strategies for promoting mental health in the workplace.
• Investigating the links between diet and cognitive function.
• How does health literacy influence individual health outcomes?
• Implications of stress on immune function.
• Effectiveness of public health campaigns on smoking cessation.
• Exploring the effectiveness of herbal remedies in treating diseases.
• The role of sports in promoting a healthy lifestyle.
• Strategies to reduce the prevalence of substance abuse.
• Pros and cons of electronic record systems in healthcare.

Clinical ideas are essential for approaching healthcare from a scientific point of view. Find some medical research paper topics to cover in your project:

• Exploring the effectiveness of novel treatments in rare diseases.
• The role of biomarkers in disease diagnosis and treatment.
• How do medical interventions influence patient satisfaction?
• Exploring links between nutrition and cancer prevention.
• How do lifestyle modifications influence diabetes management?
• Understanding the implications of drug interactions.
• How does genetic testing influence medical decision-making?
• What are some challenges associated with disseminating medical evidence?
• Predicting disease progression through machine learning.
• Assessing the accuracy of various diagnostic tools.
• Implications of medical robotics and automation in healthcare.
• Evaluating the impact of patient-centered care on quality outcomes.
• Clinical trials: Challenges and opportunities.
• How can vulnerable populations access medical care?
• How can public-private partnerships benefit healthcare delivery?

Choosing healthcare research paper topics can be quite overwhelming. We hope our suggestions will help you in developing an engaging medical research topic for your upcoming project or assignment. Remember to always check with your instructor before starting any project, so that you are aware of all specific requirements.

What Are Medical Research Paper Topics?

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500+ Medical Research Topic Ideas

Table of Contents

Medical research plays a crucial role in advancing healthcare and improving human health. It involves the scientific study of various aspects of medicine and health, including the causes, prevention, diagnosis, and treatment of diseases. Medical research is a dynamic and ever-evolving field, with new discoveries and breakthroughs happening all the time. It encompasses a wide range of disciplines, from basic science to clinical research, and involves collaboration between scientists, doctors, and other healthcare professionals. In this article, we will explore some exciting new and latest medical research topic ideas that are currently trending in the field. These Research Topics cover a variety of areas, including genetics, infectious diseases, mental health, and more.

Medical Research Topic Ideas

Medical Research Topic Ideas are as follows:

• The efficacy of mindfulness meditation in reducing symptoms of depression and anxiety
• The effects of vitamin D supplementation on bone health in postmenopausal women
• The impact of social media on body image and eating disorders in adolescents
• The effectiveness of telemedicine in improving access to healthcare in rural communities
• The benefits and risks of long-term use of statins for cholesterol management
• The role of gut microbiota in the development of autoimmune diseases
• The potential of gene therapy for the treatment of genetic disorders
• The relationship between sleep disorders and cardiovascular disease
• The use of artificial intelligence in diagnosing and treating cancer
• The effect of exercise on cognitive function in older adults
• The impact of environmental factors on the development of asthma in children
• The effectiveness of cognitive-behavioral therapy for the treatment of PTSD in veterans
• The potential benefits of psychedelic-assisted therapy for the treatment of mental illness
• The relationship between diet and risk of developing type 2 diabetes
• The role of epigenetics in the development of psychiatric disorders
• The impact of COVID-19 on mental health and well-being
• The effectiveness of mindfulness-based stress reduction in improving quality of life in cancer patients
• The impact of childhood trauma on the development of mental illness in adulthood
• The benefits and risks of hormone replacement therapy for menopausal women
• The effect of music therapy on reducing symptoms of dementia in older adults
• The relationship between gut microbiota and obesity
• The impact of socioeconomic status on health outcomes
• The effectiveness of acupuncture in treating chronic pain
• The use of stem cells in regenerative medicine
• The impact of air pollution on respiratory health
• The potential of nanotechnology in drug delivery
• The relationship between social support and mental health
• The effectiveness of mindfulness-based interventions for addiction treatment
• The role of inflammation in the development of Alzheimer’s disease
• The use of virtual reality in pain management
• The impact of exercise on mental health in adolescents
• The effectiveness of group therapy for the treatment of substance abuse
• The relationship between sleep and weight management
• The benefits and risks of using medical marijuana for chronic pain management
• The role of the immune system in the development of autoimmune diseases
• The effectiveness of cognitive rehabilitation therapy for traumatic brain injury patients
• The impact of maternal stress on fetal development
• The relationship between physical activity and cardiovascular health
• The potential of gene editing for the treatment of genetic disorders
• The effectiveness of mindfulness-based interventions for reducing symptoms of postpartum depression.
• The impact of social media on mental health
• Investigating the use of virtual reality in pain management
• The effectiveness of mindfulness-based interventions for depression
• Exploring the relationship between sleep and anxiety
• Examining the efficacy of telemedicine in delivering mental health care
• Investigating the impact of environmental factors on the development of cancer
• The effect of exercise on cognitive function in elderly individuals
• Examining the potential benefits of psychedelic-assisted therapy for PTSD
• The relationship between diet and cardiovascular disease
• Investigating the impact of air pollution on respiratory health
• Examining the effects of social isolation on mental and physical health
• The use of machine learning in diagnosing medical conditions
• Investigating the effectiveness of acupuncture in pain management
• The impact of childhood trauma on mental and physical health outcomes in adulthood
• Examining the relationship between stress and autoimmune diseases
• The effect of music therapy on mental health outcomes
• Investigating the impact of gender on healthcare outcomes
• Examining the relationship between sleep apnea and cardiovascular disease
• The effectiveness of mindfulness-based interventions for chronic pain
• Investigating the potential benefits of medical marijuana for chronic pain management
• Examining the impact of climate change on infectious disease transmission
• The use of robotics in surgery
• Investigating the relationship between alcohol consumption and cancer risk
• The effect of meditation on blood pressure control
• Examining the impact of social determinants of health on healthcare outcomes
• The role of genetics in the development of mental health conditions
• Investigating the efficacy of cognitive-behavioral therapy for anxiety disorders
• Examining the relationship between inflammation and depression
• The impact of shift work on sleep and circadian rhythms
• Investigating the potential benefits of probiotics in gut health
• Examining the relationship between diet and mental health outcomes
• The effectiveness of art therapy for individuals with dementia
• Investigating the relationship between chronic pain and mental health outcomes
• The impact of artificial intelligence on medical diagnosis and treatment
• Examining the effectiveness of exercise in treating depression
• Investigating the relationship between inflammation and cardiovascular disease
• The effect of aromatherapy on anxiety and stress
• Examining the impact of social support on mental health outcomes
• The effectiveness of hypnotherapy in pain management.
• The role of gut microbiota in immune system modulation
• Effects of intermittent fasting on insulin sensitivity in obese individuals
• Impact of smartphone usage on sleep quality and quantity
• The potential therapeutic effects of CBD on anxiety disorders
• Association between shift work and cardiovascular disease
• Efficacy and safety of psychedelic-assisted psychotherapy in treating depression
• The relationship between stress and autoimmune diseases
• Novel therapies for Alzheimer’s disease
• The effects of high-intensity interval training on metabolic syndrome
• The role of epigenetics in the development of cancer
• The effectiveness of virtual reality in pain management
• The effects of social media on body image and eating disorders
• The association between air pollution and respiratory diseases
• Effects of mindfulness meditation on stress and anxiety in healthcare workers
• The potential benefits of ketogenic diet in treating epilepsy
• The relationship between sleep apnea and cardiovascular disease
• The impact of climate change on infectious disease outbreaks
• The effectiveness of exercise in preventing falls in the elderly
• The effects of blue light exposure on circadian rhythm and sleep quality
• The association between alcohol consumption and liver disease
• The effectiveness of cognitive-behavioral therapy in treating obsessive-compulsive disorder
• The role of gut-brain axis in mental health disorders
• The association between chronic inflammation and cancer
• The efficacy and safety of probiotics in treating irritable bowel syndrome
• The effects of social isolation on mental health in the elderly
• The impact of exercise on cognitive function in Parkinson’s disease patients
• The association between vitamin D deficiency and autoimmune diseases
• The potential therapeutic effects of music therapy in dementia patients
• The effects of second-hand smoke on cardiovascular health
• The association between maternal smoking and infant health outcomes
• The role of microbiome in the development of allergies
• The association between sleep duration and obesity
• The effects of blue light-blocking glasses on sleep quality and quantity
• The potential therapeutic effects of ketamine in treating depression
• The association between gut dysbiosis and inflammatory bowel disease
• The effectiveness of cognitive rehabilitation therapy in traumatic brain injury patients
• The impact of early childhood stress on adult mental health
• The role of inflammation in the development of type 2 diabetes
• The potential benefits of plant-based diets in preventing chronic diseases.
• The effects of exercise on cognitive function in aging adults
• The association between sleep disorders and cardiovascular disease
• The potential therapeutic effects of psilocybin in treating addiction
• The role of gut microbiota in the development of autism spectrum disorder
• The effectiveness of mindfulness-based interventions in treating depression
• The effects of air pollution on cognitive function
• The association between maternal mental health and child development
• The potential therapeutic effects of cannabis in treating chronic pain
• The role of diet in the prevention and management of diabetes
• The effects of social support on mental health in cancer patients
• The association between shift work and mental health disorders
• The efficacy of antiviral therapies in treating COVID-19
• The effects of exercise on bone health in postmenopausal women
• The association between sleep disorders and obesity
• The potential therapeutic effects of mindfulness meditation in treating anxiety disorders
• The role of gut microbiota in the development of metabolic disorders
• The effectiveness of virtual reality therapy in treating phobias
• The association between social support and immune system function
• The impact of early life stress on adult cardiovascular health
• The potential benefits of intermittent fasting in cancer prevention
• The effects of air pollution on pregnancy outcomes
• The association between maternal obesity and child health outcomes
• The efficacy of cognitive-behavioral therapy in treating post-traumatic stress disorder
• The effects of sedentary behavior on metabolic health
• The potential therapeutic effects of omega-3 fatty acids in treating depression
• The role of microbiome in the development of obesity
• The association between social isolation and cognitive decline in older adults
• The impact of environmental toxins on child development
• The potential benefits of plant-based diets in treating metabolic disorders
• The effects of sleep deprivation on cognitive function
• The association between maternal stress and fetal development
• The efficacy of pharmacological interventions in treating anxiety disorders
• The effects of air pollution on respiratory health in children
• The association between social support and cardiovascular health
• The potential therapeutic effects of mindfulness meditation in treating chronic pain
• The role of diet in the prevention and management of cardiovascular disease
• The effects of exercise on mental health in children and adolescents
• The association between social support and cancer survival rates
• The impact of environmental factors on epigenetic modifications and disease susceptibility.
• The effects of exercise on immune function
• The association between maternal obesity and infant health outcomes
• The impact of air pollution on cognitive function in children
• The association between sleep deprivation and mental health disorders
• The effectiveness of virtual reality in rehabilitation after stroke
• The role of the microbiome in the development of obesity
• The impact of noise pollution on cardiovascular health
• The association between depression and cardiovascular disease
• The association between periodontal disease and cardiovascular health
• The impact of social support on mental health outcomes in cancer patients
• The potential therapeutic effects of melatonin in treating sleep disorders
• The association between air pollution and cognitive decline in older adults
• The effectiveness of group therapy in treating social anxiety disorder
• The impact of exercise on bone health in postmenopausal women
• The association between alcohol consumption and breast cancer risk
• The effects of blue light exposure on melatonin secretion and sleep quality
• The potential therapeutic effects of stem cells in treating Parkinson’s disease
• The role of inflammation in the development of depression
• The association between gut dysbiosis and depression
• The effectiveness of music therapy in reducing anxiety in cancer patients
• The impact of social media on mental health in adolescents
• The potential therapeutic effects of ketamine in treating post-traumatic stress disorder
• The association between vitamin D deficiency and cardiovascular disease
• The effects of chronic stress on immune function
• The potential benefits of Mediterranean diet in preventing cardiovascular disease
• The impact of noise pollution on sleep quality and quantity
• The association between sedentary behavior and depression
• The effects of air pollution on fetal development and pregnancy outcomes
• The potential therapeutic effects of acupuncture in treating anxiety disorders
• The role of microbiome in the development of multiple sclerosis
• The effectiveness of mindfulness-based stress reduction in treating chronic pain
• The impact of artificial sweeteners on metabolic health
• The association between sleep duration and cardiovascular disease
• The effects of social isolation on immune function in older adults
• The potential therapeutic effects of omega-3 fatty acids in treating depression.
• The effects of exercise on cognitive function in older adults
• The association between maternal mental health and infant development
• The potential therapeutic effects of probiotics in treating depression
• The impact of air pollution on lung health in children
• The association between sleep quality and academic performance in adolescents
• The effectiveness of cognitive-behavioral therapy in treating insomnia
• The role of gut microbiota in the development of metabolic syndrome
• The potential therapeutic effects of ayahuasca in treating addiction
• The impact of green space on mental health in urban areas
• The association between sedentary behavior and cardiometabolic risk factors
• The effects of blue light on mood and cognitive performance in shift workers
• The potential benefits of vegan diets in preventing chronic diseases
• The impact of social support on mental health in older adults
• The association between air pollution and lung cancer risk
• The effects of exercise on mental health in cancer survivors
• The potential therapeutic effects of ketamine in treating bipolar disorder
• The role of the microbiome in the development of rheumatoid arthritis
• The association between maternal nutrition and fetal development
• The effects of sleep deprivation on immune function
• The potential benefits of mindfulness meditation in managing chronic pain
• The impact of noise pollution on sleep-disordered breathing
• The association between sedentary behavior and breast cancer risk
• The effects of blue light exposure on retinal health
• The potential therapeutic effects of deep brain stimulation in treating depression
• The role of gut microbiota in the development of non-alcoholic fatty liver disease
• The association between air pollution and neurodegenerative diseases
• The effects of social support on immune function in cancer patients
• The potential therapeutic effects of acupuncture in treating migraines
• The impact of light pollution on sleep quality and quantity
• The association between sedentary behavior and type 2 diabetes risk
• The effects of mindfulness meditation on cognitive function in older adults
• The potential benefits of the DASH diet in preventing hypertension
• The impact of social media on body dissatisfaction and eating disorders in adolescents
• The association between air pollution and kidney disease
• The effects of chronic stress on cardiovascular health
• The potential therapeutic effects of gene therapy in treating inherited diseases
• The role of microbiome in the development of atopic dermatitis
• The association between maternal smoking and childhood obesity
• The effects of blue light exposure on visual function and eye health
• The potential therapeutic effects of electroconvulsive therapy in treating depression.

Healthcare Research Topics for College Students

• The impact of healthcare policies on patient outcomes
• The effectiveness of telemedicine in improving access to healthcare
• The role of cultural competency in healthcare delivery
• The impact of social determinants of health on healthcare outcomes
• The effectiveness of different types of healthcare interventions
• The role of genetics in predicting and preventing chronic diseases
• The impact of the opioid epidemic on healthcare delivery
• The effectiveness of alternative medicine in managing chronic conditions
• The role of technology in improving patient safety
• The impact of healthcare provider burnout on patient care
• The effectiveness of different healthcare models in managing chronic diseases
• The role of patient education in improving healthcare outcomes
• The impact of healthcare disparities on access to care and health outcomes
• The effectiveness of healthcare systems in responding to public health emergencies
• The role of nutrition in disease prevention and management
• The impact of healthcare policy on healthcare costs and spending
• The effectiveness of mental health interventions in improving overall health outcomes
• The role of healthcare systems in addressing health disparities
• The impact of healthcare data analytics on clinical decision making
• The effectiveness of healthcare interventions in reducing healthcare-associated infections
• The role of patient-centered care in improving healthcare outcomes
• The impact of healthcare regulations on patient safety
• The effectiveness of vaccination programs in preventing infectious diseases
• The role of healthcare systems in promoting healthy lifestyle behaviors
• The impact of chronic diseases on healthcare costs and quality of life
• The effectiveness of preventative healthcare in improving health outcomes
• The role of healthcare technology in improving healthcare delivery
• The impact of healthcare funding on healthcare outcomes
• The effectiveness of healthcare interventions in managing chronic pain
• The role of healthcare providers in promoting health equity.

Community Medicine Research Topics for Medical Students

• The impact of community-based interventions on reducing the burden of non-communicable diseases in low-income communities.
• The effectiveness of vaccination campaigns in preventing infectious diseases in marginalized communities.
• The relationship between air pollution and respiratory health in urban communities.
• The prevalence and risk factors of substance abuse among homeless populations.
• The impact of social determinants of health on health outcomes in rural communities.
• The role of community health workers in improving maternal and child health outcomes in low-resource settings.
• The association between food insecurity and obesity in low-income populations.
• The prevalence and risk factors of mental health disorders among adolescents in urban communities.
• The effectiveness of school-based health promotion programs in improving health behaviors among children and adolescents.
• The role of community-based participatory research in addressing health disparities in underserved populations.
• The impact of social support networks on mental health outcomes among elderly populations.
• The relationship between access to healthcare services and health outcomes in rural communities.
• The effectiveness of smoking cessation interventions in reducing the burden of tobacco-related diseases.
• The prevalence and risk factors of sexually transmitted infections among young adults in urban communities.
• The role of community-based organizations in promoting healthy behaviors and preventing chronic diseases.
• The impact of climate change on the incidence and distribution of infectious diseases.
• The prevalence and risk factors of intimate partner violence among women in low-income communities.
• The effectiveness of health education programs in improving health literacy and health outcomes in underserved populations.
• The relationship between social support and adherence to treatment among patients with chronic diseases.
• The prevalence and risk factors of hypertension and diabetes in urban communities.
• The impact of community-based interventions on reducing healthcare costs and improving health outcomes.
• The role of mobile health technologies in improving access to healthcare services in rural communities.
• The prevalence and risk factors of obesity among children and adolescents in low-income communities.
• The effectiveness of community-based interventions in promoting healthy behaviors among pregnant women.
• The impact of housing conditions on health outcomes in marginalized communities.
• The relationship between access to healthy food and health outcomes in urban communities.
• The prevalence and risk factors of depression among elderly populations in rural communities.
• The role of social media in promoting healthy behaviors and preventing diseases among young adults.
• The effectiveness of telemedicine in improving access to healthcare services in underserved populations.
• The prevalence and risk factors of infectious diseases among migrant populations in urban areas.

Surgery Research Topics for Medical Students

• The efficacy and safety of minimally invasive surgery for various conditions
• Comparison of laparoscopic and open surgery for common procedures
• The impact of surgeon experience on surgical outcomes
• Analysis of postoperative complications and their management
• The role of robotics in surgery
• Investigating the use of artificial intelligence in surgery
• The effectiveness of non-pharmacological pain management techniques after surgery
• The effect of preoperative anxiety on postoperative recovery
• Evaluation of different surgical approaches for breast cancer treatment
• The benefits and risks of surgical treatment for obesity
• Investigating the use of stem cells in tissue repair following surgery
• The influence of nutrition on postoperative recovery and wound healing
• Analysis of the psychological impact of surgery on patients
• The effect of different anesthesia methods on postoperative outcomes
• Comparison of outcomes between day surgery and inpatient surgery
• Evaluation of the use of surgical checklists in improving patient safety
• The impact of age on surgical outcomes and recovery
• Investigating the use of 3D printing in surgical planning and implant design
• The benefits and risks of bariatric surgery in patients with diabetes
• The role of surgery in the treatment of chronic pain
• The efficacy of arthroscopic surgery for joint conditions
• The use of lasers in surgery
• Investigating the use of virtual reality in surgical training and education
• The effect of preoperative counseling on patient satisfaction and outcomes
• The impact of comorbidities on surgical outcomes
• Analysis of the economic impact of different surgical approaches
• Investigating the use of telemedicine in surgical consultations and follow-up care
• The effectiveness of surgical treatment for endometriosis
• Comparison of outcomes between single-incision and multiport laparoscopic surgery
• The use of robotics in urologic surgery.

Research Projects for Undergraduate Medical Students

• Investigating the role of genetics in the development of cancer
• Analyzing the effectiveness of different types of pain management strategies in postoperative patients
• Evaluating the impact of diet and exercise on obesity-related health outcomes
• Examining the relationship between sleep quality and mental health in medical students
• Investigating the efficacy of different types of antibiotics in treating common bacterial infections
• Analyzing the impact of electronic medical record systems on patient care
• Evaluating the effectiveness of different types of vaccines in preventing infectious diseases
• Examining the relationship between maternal nutrition and fetal development
• Investigating the use of telemedicine in delivering healthcare services to rural populations
• Analyzing the impact of smoking on lung function and respiratory health
• Evaluating the effectiveness of different types of rehabilitation programs for stroke patients
• Examining the relationship between physical activity and cardiovascular health
• Investigating the use of stem cells in treating various medical conditions
• Analyzing the impact of stress on mental and physical health outcomes
• Evaluating the effectiveness of different types of medical interventions in managing chronic pain
• Examining the relationship between social support and mental health outcomes in patients with chronic illnesses
• Investigating the use of mindfulness-based interventions in reducing anxiety and depression
• Analyzing the impact of environmental factors on health outcomes in urban populations
• Evaluating the effectiveness of different types of cancer treatments, such as chemotherapy, radiation therapy, and surgery
• Examining the relationship between nutrition and mental health in older adults
• Investigating the use of mobile health technologies in promoting healthy behaviors
• Analyzing the impact of air pollution on respiratory health in children
• Evaluating the effectiveness of different types of treatments for substance use disorders
• Examining the relationship between socioeconomic status and health outcomes
• Investigating the use of music therapy in managing pain and anxiety in hospitalized patients
• Analyzing the impact of social media on mental health outcomes in adolescents
• Evaluating the effectiveness of different types of interventions in managing symptoms of depression and anxiety in cancer patients
• Examining the relationship between sleep and cognitive function in older adults
• Investigating the use of animal-assisted therapy in promoting physical and mental health
• Analyzing the impact of climate change on health outcomes in vulnerable populations

About the author

Muhammad Hassan

Researcher, Academic Writer, Web developer

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A Realistic Guide to Medical School

Written by UCL students for students

Top 10 Tips: Getting into Research as a Medical Student

Introducing our new series: Top 10 Tips – a simple guide to help you achieve your goals!

In this blog post, Jessica Xie (final year UCL medical student) shares advice on getting into research as a medical student.

Disclaimers: 

• Research is not a mandatory for career progression, nor is it required to demonstrate your interest in medicine. 
• You can dip into and out of research throughout your medical career. Do not feel that you must continue to take on new projects once you have started; saying “no, thank you” to project opportunities will allow you to focus your energy and time on things in life that you are more passionate about for a more rewarding experience.
• Do not take on more work than you are capable of managing. Studying medicine is already a full-time job! It’s physically and mentally draining. Any research that you get involved with is an extracurricular interest.

I decided to write this post because, as a pre-clinical medical student, I thought that research only involved wet lab work (i.e pipetting substances into test tubes). However, upon undertaking an intercalated Bachelor of Science (iBSc) in Primary Health Care, I discovered that there are so many different types of research! And academic medicine became a whole lot more exciting…

Here are my Top 10 Tips on what to do if you’re a little unsure about what research is and how to get into it:

TIP 1: DO YOUR RESEARCH (before getting into research)

There are three questions that I think you should ask yourself:

• What are my research interests?

Examples include a clinical specialty, medical education, public health, global health, technology… the list is endless. Not sure? That’s okay too! The great thing about research is that it allows deeper exploration of an area of Medicine (or an entirely different field) to allow you to see if it interests you.

2.  What type of research project do I want to do?

Research evaluates practice or compares alternative practices to contribute to, lend further support to or fill in a gap in the existing literature.

There are many different types of research – something that I didn’t fully grasp until my iBSc year. There is primary research, which involves data collection, and secondary research, which involves using existing data to conduct further research or draw comparisons between the data (e.g. a meta-analysis of randomised control trials). Studies are either observational (non-interventional) (e.g. case-control, cross-sectional) or interventional (e.g. randomised control trial).

An audit is a way of finding out if current practice is best practice and follows guidelines. It identifies areas of clinical practice could be improved.

Another important thing to consider is: how much time do I have? Developing the skills required to lead a project from writing the study protocol to submitting a manuscript for publication can take months or even years. Whereas, contributing to a pre-planned or existing project by collecting or analysing data is less time-consuming. I’ll explain how you can find such projects below.

3.  What do I want to gain from this experience?

Do you want to gain a specific skill? Mentorship? An overview of academic publishing? Or perhaps to build a research network?

After conducting a qualitative interview study for my iBSc project, I applied for an internship because I wanted to gain quantitative research skills. I ended up leading a cross-sectional questionnaire study that combined my two research interests: medical education and nutrition. I sought mentorship from an experienced statistician, who taught me how to use SPSS statistics to analyse and present the data.

Aside from specific research skills, don’t forget that you will develop valuable transferable skills along the way, including time-management, organisation, communication and academic writing! 

TIP 2: BE PROACTIVE

Clinicians and lecturers are often very happy for medical students to contribute to their research projects. After a particularly interesting lecture/ tutorial, ward round or clinic, ask the tutor or doctors if they have any projects that you could help them with! 

TIP 3: NETWORKING = MAKING YOUR OWN LUCK

Sometimes the key to getting to places is not what you know, but who you know. We can learn a lot from talking to peers and senior colleagues. Attending hospital grand rounds and conferences are a great way to meet people who share common interests with you but different experiences. I once attended a conference in Manchester where I didn’t know anybody. I befriended a GP, who then gave me tips on how to improve my poster presentation. He shared with me his experience of the National institute of Health Research (NIHR) Integrated Academic Training Pathway and motivated me to continue contributing to medical education alongside my studies.

TIP 4: UTILISE SOCIAL MEDIA

Research opportunities, talks and workshops are advertised on social media in abundance. Here are some examples:

Search “medical student research” or “medsoc research” into Facebook and lots of groups and pages will pop up, including UCL MedSoc Research and Academic Medicine (there is a  Research Mentoring Scheme Mentee Scheme), NSAMR – National Student Association of Medical Research and International Opportunities for Medical Students .

Search #MedTwitter and #AcademicTwitter to keep up to date with ground-breaking research. The memes are pretty good too.

Opportunities are harder to come by on LinkedIn, since fewer medical professionals use this platform. However, you can look at peoples’ resumes as a source of inspiration. This is useful to understand the experiences that they have had in order to get to where they are today. You could always reach out to people and companies/ organisations for more information and advice.

TIP 5: JOIN A PRE-PLANNED RESEARCH PROJECT

Researchers advertise research opportunities on websites and via societies and organisations such as https://www.remarxs.com and http://acamedics.org/Default.aspx . 

TIP 6: JOIN A RESEARCH COLLABORATIVE

Research collaboratives are multiprofessional groups that work towards a common research goal. These projects can result in publications and conference presentations. However, more importantly, this is a chance to establish excellent working relationships with like-minded individuals.

Watch out for opportunities posted on Student Training and Research Collaborative .

Interested in academic surgery? Consider joining StarSurg , BURST Urology , Project Cutting Edge or Academic Surgical Collaborative .

Got a thing for global health? Consider joining Polygeia . 

TIP 7: THE iBSc YEAR: A STEPPING STONE INTO RESEARCH

At UCL you will complete an iBSc in third year. This is often students’ first taste of being involved in research and practicing academic writing – it was for me. The first-ever project that I was involved in was coding data for a systematic review. One of the Clinical Teaching Fellows ended the tutorial by asking if any students would be interested in helping with a research project. I didn’t really know much about research at that point and was curious to learn, so I offered to help. Although no outputs were generated from that project, I gained an understanding of how to conduct a systematic review, why the work that I was contributing to was important, and I learnt a thing or two about neonatal conditions. 

TIP 8: VENTURE INTO ACADEMIC PUBLISHING

One of the best ways to get a flavour of research is to become involved in academic publishing. There are several ways in which you could do this:

Become a peer reviewer. This role involves reading manuscripts (papers) that have been submitted to journals and providing feedback and constructive criticism. Most journals will provide you with training or a guide to follow when you write your review. This will help you develop skills in critical appraisal and how to write an academic paper or poster. Here are a few journals which you can apply to:

• https://thebsdj.cardiffuniversitypress.org
• Journal of the National Student Association of Medical Researchjournal.nsamr.ac.uk
• https://cambridgemedicine.org/about  
• https://www.bmj.com/about-bmj/resources-reviewers  

Join a journal editorial board/ committee. This is a great opportunity to gain insight into how a medical journal is run and learn how to get published. The roles available depend on the journal, from Editor-in-Chief to finance and operations and marketing. I am currently undertaking a Social Media Fellowship at BJGP Open, and I came across the opportunity on Twitter! Here are a few examples of positions to apply for:

• Journal of the National Student Association of Medical Researchjournal.nsamr.ac.uk – various positions in journalism, education and website management
• https://nsamr.ac.uk – apply for a position on the executive committee or as a local ambassador
• Student BMJ Clegg Scholarship
• BJGP Open Fellowships

TIP 9: GAIN EXPERIENCE IN QUALITY IMPROVEMENT

UCL Be the Change is a student-led initiative that allows students to lead and contribute to bespoke QIPs. You will develop these skills further when you conduct QIPs as part of your year 6 GP placement and as a foundation year doctor.

TIP 10: CONSIDER BECOMING A STUDENT REPRESENTATIVE

You’ll gain insight into undergraduate medical education as your role will involve gathering students’ feedback on teaching, identifying areas of curriculum that could be improved and working with the faculty and other student representatives to come up with solutions. 

It may not seem like there are any research opportunities up for grabs, but that’s where lateral thinking comes into play: the discussions that you have with your peers and staff could be a source of inspiration for a potential medical education research project. For example, I identified that, although we have lectures in nutrition science and public health nutrition, there was limited clinically-relevant nutrition teaching on the curriculum. I then conducted a learning needs assessment and contributed to developing the novel Nutrition in General Practice Day course in year 5.

Thanks for reaching the end of this post! I hope my Top 10 Tips are useful. Remember, research experience isn’t essential to become a great doctor, but rather an opportunity to explore a topic of interest further.

One thought on “Top 10 Tips: Getting into Research as a Medical Student”

This article was extremely helpful! Alothough, I’m only a junior in high school I have a few questions. First, is there anyway to prepare myself mentally for this challenging road to becoming a doctor? check our PACIFIC best medical college in Rajasthan

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How to get involved in research as a medical student

• Related content
• Peer review
• Anna Kathryn Taylor , final year medical student 1 ,
• Sarah Purdy , professor of primary care and associate dean 1
• 1 Faculty of Health Sciences, University of Bristol, UK

Participating in research gives students great skills and opportunities. Anna Taylor and Sarah Purdy explain how to get started

This article contains:

-How to get involved with research projects

-Questions to ask yourself before starting research

-What can you get published? Research output

-Advice for contacting researchers

-Different types of research explained

-Stages of research projects

Students often go into medicine because of a desire to help others and improve patients’ physical and mental wellbeing. In the early years of medical school, however, it can seem as if you are not making much difference to patient care. Involvement in research can provide exciting opportunities to work as part of a team, improve career prospects, and most importantly add to the evidence base, leading to better outcomes for patients.

Research is usually multidisciplinary, including clinical academics (medical doctors who spend part of their working life doing research), nurses, patients, scientists, and researchers without a medical background. Involvement in such a team can improve your communication skills and expand your understanding of how a multidisciplinary team works.

Participating in research can also help you to develop skills in writing and critical appraisal through the process of publishing your work. You may be able to present your work at conferences—either as a poster or an oral presentation—and this can provide valuable points for job applications at both foundation programme and core training level. This is particularly important if you are considering a career in academia. You will also develop skills in time management, problem solving, and record keeping. You might discover an area of medicine in which you are keen to carry out further work. For some people, getting involved in research as a medical student can be the first step in an academic career.

Kyla Thomas, National Institute for Health Research clinical lecturer in public health at the University of Bristol, says, “my first baby steps into a clinical academic career started with a research project I completed as a medical student. That early involvement in research opened my eyes to a whole new world of opportunities that I never would have considered.

“Importantly, participating in undergraduate research sets students apart from their colleagues. Applying for foundation posts is a competitive process and it is a definite advantage if you have managed to obtain a peer reviewed publication.”

Getting involved with research projects

Although it is possible to do research at medical school, it is important to be realistic about how much free time you have. It might be possible to set up your own research project, but this will require substantial planning in terms of writing research protocols, gaining ethical approval, and learning about new research methodologies. Other opportunities for research that make less demands on your time include:

Intercalated degrees—these often have time set aside for research in a specific area, so it is important to choose your degree according to what you might like to do for your dissertation (for example, laboratory-based work in biochemistry, or qualitative research in global health. Some subjects may have options in both qualitative and quantitative research).

Student selected components or modules can provide a good opportunity to be involved in an ongoing study or research project. If you have a long project period, you might be able to develop your own small project.

Electives and summer holidays can also provide dedicated time for research, either within the United Kingdom or in another country. They can allow you to become established in a research group if you’re there for a few weeks, and can lead to a longstanding relationship with the research group if you continue to work with them over your medical school career.

If you don’t know what to do, contacting the Student Audit and Research in Surgery (STARSurg), 1 the National Student Association of Medical Research (NSAMR), 2 or your medical school’s research society may be a good place to start.

The INSPIRE initative, 3 coordinated by the Academy of Medical Sciences, gives support and grants to help students take part in research. Some UK medical schools have small grants for elective and summer projects, and organise taster days for students to get an idea of different research areas.

You may also be able to access other grants or awards to support your research. Some of the royal colleges, such as the Royal College of General Practitioners and the Royal College of Psychiatrists, offer bursaries to students doing research in their holidays or presenting at conferences. Other national organisations, such as the Medical Women’s Federation, offer bursaries for elective projects.

Box 1: Questions to ask yourself before starting research

What are you interested in? There is no point getting involved in a project area that you find boring.

How much time do you have available? It is crucial to think about this before committing to a project, so that your supervisor can give you an appropriate role.

What do you want to get out of your research experience? Do you want a brief insight into research? Or are you hoping for a publication or presentation?

Do you know any peers or senior medical students who are involved in research? Ask them about their experiences and whether they know of anyone who might be willing to include you in a project.

Box 2: Research output

Publication —This is the “gold standard” of output and usually consists of an article published in a PubMed ID journal. This can lead to your work being cited by another researcher for their paper, and you can get up to two extra points on foundation programme applications if you have published papers with a PubMed ID.

Not all research will get published, but there are other ways to show your work, such as presenting at conferences:

Oral presentation —This involves giving a short talk about your research, describing the background, methods, and results, then talking about the implications of your findings.

Poster presentation —This involves creating a poster, usually A1 or A2 in size, summarising the background, methods, and results of your research. At a conference, presenters stand by their poster and answer questions from other delegates.

Contacting researchers

Most universities have information about their research groups on their websites, so spend some time exploring what studies are being carried out and whether you are interested in one of the research topics.

When contacting a member of the research group, ask if they or someone else within their team would be willing to offer you some research experience. Be honest if you don’t have any prior experience and about the level of involvement you are looking for, but emphasise what it is about their research that interests you and why you want to work with them. It’s important to have a flexible approach to what they offer you—it may not initially sound very exciting, but it will be a necessary part of the research process, and may lead to more interesting research activity later.

Another way to make contact with researchers is at university talks or lectures. It might be intimidating to approach senior academics, but if you talk to them about your interest they will be more likely to remember you if you contact them later on.

Box 3: What can students offer research teams?—Views from researchers

“Medical students come to research with a ‘fresh eyes’ perspective and a questioning mindset regarding the realities of clinical practice which, as a non-medic myself, serves to remind me of the contextual challenges of implementing recommendations from our work.”

Alison Gregory, senior research associate, Centre for Academic Primary Care, University of Bristol, UK.

“Enthusiasm, intelligence, and a willingness to learn new skills to solve challenges—bring those attributes and you’ll be valuable to most research teams.”

Tony Pickering, consultant anaesthetist and Wellcome Trust senior research fellow, University of Bristol, UK.

Box 4: Different types of research

Research aims to achieve new insights into disease, investigations, and treatment, using methodologies such as the ones listed below:

Qualitative research —This can be used to develop a theory and to explain how and why people behave as they do. 4 It usually involves exploring the experience of illness, therapeutic interventions, or relationships, and can be compiled using focus groups, structured interviews, consultation analysis, 5 or ethnography. 6

Quantitative research —This aims to quantify a problem by generating numerical data, and may test a hypothesis. 7 Research projects can use chemicals, drugs, biological matter, or even computer generated models. Quantitative research might also involve using statistics to evaluate or compare interventions, such as in a randomised controlled trial.

Epidemiological research —This is the study of the occurrence and distribution of disease, the determinants influencing health and disease states, and the opportunities for prevention. It often involves the analysis of large datasets. 4

Mixed methods research —This form of research incorporates both quantitative and qualitative methodologies.

Systematic reviews —These provide a summary of the known evidence base around a particular research question. They often create new data by combining other quantitative (meta-analysis) or qualitative (meta-ethnography) studies. They are often used to inform clinical guidelines.

Box 5: Stages of research projects

Project conception—Come up with a hypothesis or an objective for the project and form the main research team.

Write the research protocol—Produce a detailed description of the methodology and gain ethical approval, if needed.

Carry out the methodology by collecting the data.

Analyse the data.

Decide on the best way to disseminate your findings—for example, a conference presentation or a publication—and where you will do this.

Write up your work, including an abstract, in the format required by your chosen journal or conference.

Submit . For conference abstracts, you may hear back swiftly whether you have been offered the chance to present. Publication submissions, however, must be peer reviewed before being accepted and it can take over a year for a paper to appear in print.

Originally published as: Student BMJ 2017;25:i6593

Competing interests: AKT received grant money from INSPIRE in 2013.

Provenance and peer review: Not commissioned; externally peer reviewed.

• ↵ STARSurg. Student Audit and Research in Surgery. 2016. www.starsurg.org .
• ↵ NSAMR. National Student Association of Medical Research. 2016. www.nsamr.org .
• ↵ The Academy of Medical Sciences. About the INSPIRE initiative. 2016. www.acmedsci.ac.uk/careers/mentoring-and-careers/INSPIRE/about-INSPIRE/ .
• ↵ Ben-Shlomo Y, Brookes ST, Hickman M. Lecture Notes: Epidemiology, Evidence-based Medicine and Public Health. 6th ed . Wiley-Blackwell, 2013 .
• ↵ gp-training.net. Consultation Theory. 2016. www.gp-training.net/training/communication_skills/consultation/consultation_theory.htm .
• ↵ Reeves S, Kuper A, Hodges BD. Qualitative research methodologies: ethnography. BMJ 2008 ; 337 : a1020 . doi:10.1136/bmj.a1020   pmid:18687725 . OpenUrl FREE Full Text
• ↵ Porta M. A Dictionary of Epidemiology. 5th ed . Oxford University Press, 2008 .

Comprehensive Guide to Research from the Perspective of a Medical Student

• By Dmitry Zavlin, M.D.
• February 9, 2017
• Medical Student , Pre-med

G uest post from Dmitry Zavlin, MD, a research fellow in Houston, Texas. He has been highly productive in his research endeavors and below describes a comprehensive guide to getting involved in research.

Without any doubt whatsoever, high USMLE scores, strong recommendation letters from faculty members, a multitude of away rotations, and an updated and accurate résumé make up the foundation of a strong application for a residency position. Nevertheless, from my personal experience, one topic remains crucial that many medical students either love or hate (or try not to think about it): research . It is an extracurricular activity that enables someone to stand out from the crowd and present oneself as a diverse and multitasking character. These traits are especially favorable when it comes to applying to competitive residency programs with high applicant to position ratios. I encourage every future graduate to look into this topic since – and as astonishing as this may seem – medical school is the ideal opportunity to get your name out there. You don’t need to take a year off from classes or be on an M.D., Ph.D. track. Even those students that do not seek academic careers have a benefit from engaging in scientific duties . It helps you understand the mechanisms of research, the bureaucratic obstacles, the medical challenges, and teaches you communication with peers and faculty. Furthermore, you learn how to read, analyze, and interpret scientific publications of others. And trust me, it’s not all gold that gets printed in journals . On first glance, getting involved in unpaid ventures while you are in class, on rotation, at home studying or just taking some time off for yourself might seem like a bad deal. Yet with a sincere approach towards this subject, you can strengthen your résumé, top off your application, and learn skills that will serve you well into your career as a doctor.

The following lines are intended to display my personal experience that I have made at my medical school and in my interactions with students, residents, fellows, and attendings at my current position.

Choosing your Project

First things first. Naturally, you would want to participate and conduct research in a field of medicine you might see yourself in after graduation. However, as mentioned before, this is not a K.O. criterion. Plenty of personal experiences tell me stories of students who were involved in one area and then switched and matched in a completely different specialty of medicine or completely left the patient-care sector. Therefore, consider your engagement in scientific tasks more of as a symbolization for your work ethic and your ability to perform in a team.

My first tip is to contact the department at your home medical school, introduce yourself, write 1-2 sentences describing your motivations and goals, and ask to sit down with some faculty members or scientific staff to discuss your involvement in any research activities.

Larger departments usually have secretaries or an academic office where your email is less likely to get lost compared to the inbox of a busy professor who receives hundreds of emails per day. Personally, I would aim for junior faculty and potentially senior residents who are experienced enough to conduct research on a high level but are not too far away from the life of a young medical student. Certain departments further have specific full-time research staff that is definitely a great resource for any scientific venture. While it may be helpful to work with the director and senior faculty directly, the sad reality is often that they typically have many academic and administrative duties and activities at their institutions that might not go along well with the schedule of an ambitious student and cause frustration in the long run.

When you meet, make sure to gain and write down as many details as possible:

• What is the topic, what is the goal of this project?
• What type of format is it? (See below)
• What is the current status?
• Who is involved in this research project, what is the team, what are the people to contact?
• What will be my duties?
• Any bureaucratic issues to be aware of (IRB approval, grants, finances)?
• What is the prognosis? Are there any deadlines?

Lastly, ask about the current literature on that topic so you know what your team’s role is going to be in this scientific field. Although one core concept of any research result is reproducibility, it often remains a challenge to publish a project that has already been performed and presented or printed before. Getting involved in an area that is in quick development with high turnaround is subsequently a strong recommendation.

Types of Evidence-Based Research

Now, I would like to talk about the most common options you will encounter when presented with an array of project offers. That way you know their perks and pitfalls before you commit to anything serious and long-lasting and potentially even waste any valuable and limited time of yours.

• Case Reports: These are the most basic and least powerful of scientific contributions to medicine. Give or take, a case report is the summarized hospital or clinic chart of a treated patient who presented with a problem A and was managed with therapy B. A case report that is typically 2-3 pages long with a short intro, a compact case discussion, and perhaps some photos is the closest thing you will get to a patient note you learned to write in early medical school. Their lack of medical value makes them hard to get published in journals and students should not solely rely on these projects as they may not ultimately be accepted by journals. Recommendation: 3/5
• Case Series, Retrospective Study: These layouts are my personal recommendation as they allow quality results within a short period and are not time-consuming or require large long-term commitment as others. Typical examples are an analysis of patients who presented with the same diagnosis or underwent an identical procedure. The difference between a case series and a retrospective study is that for the latter, the patients can be stratified into different subgroups (similar to “case control study”) and statistical calculations can be performed to achieve significant conclusions. Recommendation: 5/5
• Prospective Studies: In these studies, patients are gathered in one or multiple cohorts and are followed-up over long periods of time by lab results, imaging, physical exams etc. These require great time commitment and, from a student perspective, typically only allow a certain amount of participation. These are usually studies for physicians with long relationships with their patients. Recommendation: 3/5
• (Randomized) Clinical Trials : The peak of evidence-based medical research. Similar as prospective studies yet require more planning, IRB approval, and lots of work with industry, grants, protocols, etc. Student involvement is usually marginal. Recommendation: 2/5
• Basic Science, Animal Work: Although these projects require training, approval, and a large amount of preparation, student participation is common in many areas of basic science. The advantage of these laboratory activities is a certain amount of flexibility on when certain tasks and duties can be performed. Within certain limitations, a medical student can get involved in animal or basic science research and assist in specific jobs suitable to his or her personal schedule. Even partial involvement can be enough to get one’s name on a publication. However, lab work can be monotonous and frustrating at times when experiments do not deliver the anticipated results. Sitting in non-stimulation laboratories requires a certain type of character. Recommendation: 4/5
• Descriptions of Innovations: Purely descriptive publications of new surgical techniques, innovative technology, new pharmaceutical drugs, or simply personal statements on evolving subjects, etc. This type of work often demands a given level of expertise and is not typically suitable for graduate research. Recommendation: 2/5
• Reviews, Meta-Analyses: These types of written compositions are based on a literature review. The author’s job is to read through countless, often hundreds of previous publications and create a summary regarding a specific medical topic. Reviews and meta-analysis are particularly useful for issues that are prevalent and have delivered many reports in the past. Whereas a review merely lists the findings of previous research groups, a meta-analysis is able to pool data and conduct statistical analyses. These projects allow great flexibility and can be finished from any location but do not underestimate the time needed to achieve proper results. Recommendation: 4/5

Formats of Publication

What follows is a list of mediums that allow you to get your work to the public. Albeit the concept of most research activities is similar and progresses on akin paths, it is important to agree on a goal early in the research process. Journal articles, for example need to be of highest quality and impeccable when submitted. Presentations must be tailored accordingly depending on what audience you are planning to address. Book chapters need clear guidelines to ensure that your handiwork fits well to the other parts of the volume. Make sure to discuss this topic with your seniors to understand their expectations from you.

• Journal Articles: These are the highest quality format that you can use to submit your research work for the world to see. Upon arrival at the journal’s office, the editorial office first reviews your manuscript and determines its eligibility. Next, it is sent off to a number of anonymous reviewers who judge your documents and suggest if it is worth publication, if it needs changes, or if it should be rejected. Being an author on articles in peer-reviewed journal is the strongest support to improve your application. Recommendation: 5/5
• Podium Presentations: These are typically 5-15min PowerPoint conferences or similar in front of regional, national, and international audiences of students, residents, nurses, scientists, and board-certified physicians. While your work might be less accessible to the world than published articles, it is still recommended to submit your accomplishments to such conventions. Aim for national conferences rather than regional ones. Recommendation: 4/5 for (inter)national, 3/5 for regional conferences
• Poster Presentations: A classic poster session is where you travel to a conference, hang your poster with a summary of your research findings (similar to a short abstract) and are available for others to review your work and ask questions. In some cases, poster sessions are requested by conferences when you apply for podium presentations but your projects are not considered beneficial enough. Recommendation: 3/5
• Book Chapters: Senior physicians, faculty members, or experts on a certain field are sometimes asked to write segments of medical or scientific books that are soon to be brought on sale to the market. In certain cases, students or residents write segments of such book chapters for the senior author. From personal experience, these projects are a long-term process as they go into extreme medical detail. On the upside, publication with your name on it is almost guaranteed. Unfortunately, these types of publications are not of high evidence-based research and should only be considered as a secondary side project Recommendation: 3/5

Basic and Necessary Know-How

After choosing your project you need to learn and understand how the scientific process works once you have your results ready for publication. Conducting the studies, experiments, and the literature reviews is one part of the research job. Presenting your findings is the other side of the coin. Read many publications on the same subject and study what a paper is supposed to look like. Analyze the language the authors use. It has to be straight to the point, factual, objective, leave out unnecessary information yet avoid long soporific segments of repeating details. Your audience will want to hear a hypothesis, the methodology of your venture on how said hypothesis should be tested, your results, and an antiseptic interpretation thereof. Having a senior writer review your work is therefore crucial in the beginnings of a research career.

Next, and this may seem like a no-brainer, learn how to properly and efficiently use today’s available technology to your advantage. Learn the most important features of your word processing software. Get access to a tool that allows to sort and list literature references and full versions of articles, preferably in PDF format. If you share files with others or work simultaneously at different sites, use a cloud service to keep your files in synchronization across all your devices. Any photo, video, or graph-editing software with some artistic skills might come in handy as well. Lastly, learn some basic mathematical and statistical skills and obtain a statistical software. Research is nothing if you cannot back up your story by some hard numbers. Study what a t-test, a type I error, and a type II error are and how they work. Understand when you have to use chi-square and when the Fisher’s exact test . This list goes on and on. You do not need a Ph.D. degree in biometrics or stochastic calculus to be involved in medical research but even basic skills can set you far ahead of others and you will stand out from the crowd. Additionally, all these things I just mentioned facilitate your projects by incredible amounts and allow you to publish your results faster. Capitalize on the technology that is available today!

Finally, learn how to revise current literature and how to look for references to back up your ideas or contrast your data to those of other groups. In the end, research is a competition almost like any other business sector; except that money is not necessarily the number one objective but rather prestige and impact.  Pubmed is a valuable search engine, for instance, that allows you to go through the MEDLINE database and find similar publications to your project. UpToDate is a practical tool that is constantly refreshed by countless experts and gives access to the latest guidelines on specific topics. One of my former attendings always said that publishing a paper is like selling a car: you have to know the market and emphasize the upsides of your work to gain interest of others. Have all these files clean and tide on your computer from day 1, so you can keep a good overview of things and track your progress.

Further Aspects to Consider

When you start a new research project, figure out who your team is that you will be working with as this will determine the authors and their order on a potential publication. Make sure your name appears on the final manuscript if you have brought significant effort and input towards the project. As the New England Journal of Medicine, one of the largest and most prestigious journals in the field, states:

“Credit for authorship requires (a) substantial contributions to the conception and design; or the acquisition, analysis, or interpretation of the data, (b) the drafting of the article or critical revision for important intellectual content, (c) final approval of the version to be published, and (d) agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the article are appropriately investigated and resolved.”

The more work you put in, the further your name should appear up front. The final position of a scientific publication is usually reserved for the senior author (principal investigator) and the head of the team.

The last issue that needs to be mentioned here are finances. Even if you are working on a retrospective study and are just simply scrolling through patient charts to gather data, special software, travel to conferences, fees for journals (author processing charge for open access) can rapidly add up. Basic science ventures may require additional funding. Knowing your resources is crucial for any research. The discussion of money may seem like a sensitive subject and “above your pay grade” yet I recommend approaching this topic with open cards when the right moment comes.

Final Words

Despite the downsides of scientific work, I still believe the majority of students should experience the art of research that has made medicine what it is now. Yes, research is frequently frustrating and consumes many of your physical and mental resources. Yes, a majority of jobs after residency do not include research. Still, I will never forget the great feeling of my first accepted publication and when I immediately continued to strive towards the next challenge. Henceforward, research had something rewarding and appealing about it. In the long run, this highly dynamic profession is probably not suited for all future physicians, yet I can only repeat myself and encourage everyone to give it a try.

Dmitry Zavlin graduated with an M.D. from the Technical University of Munich in 2015.

He currently works as a research fellow in Houston.

To contact the author, please visit www.zavlin.com

Dmitry Zavlin, M.D.

First Day of Medical School – 4 Things to Know

Medical school is a completely different beast from your pre-med years in college. Here are four things you should know and prepare for in order to have the most productive, effective, and happy experience of medical school!

Premed and Medical Student Summer Research Guide

We break down the value of summer research, how to find research positions, and tips to make the most of summer research opportunities.

How to Find an Undergraduate Research Position

Research is a crucial component of any medical school application. Utilize the following tips to streamline the process of finding an ideal research position.

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• Open access
• Published: 26 November 2018

The 150 most important questions in cancer research and clinical oncology series: questions 94–101

Edited by Cancer Communications

Cancer Communications

Cancer Communications volume  38 , Article number:  69 ( 2018 ) Cite this article

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Since the beginning of 2017, Cancer Communications (former title: Chinese Journal of Cancer ) has published a series of important questions regarding cancer research and clinical oncology, to provide an enhanced stimulus for cancer research, and to accelerate collaborations between institutions and investigators. In this edition, the following 8 valuable questions are presented. Question 94. The origin of tumors: time for a new paradigm? Question 95. How can we accelerate the identification of biomarkers for the early detection of pancreatic ductal adenocarcinoma? Question 96. Can we improve the treatment outcomes of metastatic pancreatic ductal adenocarcinoma through precision medicine guided by a combination of the genetic and proteomic information of the tumor? Question 97. What are the parameters that determine a competent immune system that gives a complete response to cancers after immune induction? Question 98. Is high local concentration of metformin essential for its anti-cancer activity? Question 99. How can we monitor the emergence of cancer cells anywhere in the body through plasma testing? Question 100. Can phytochemicals be more specific and efficient at targeting P-glycoproteins to overcome multi-drug resistance in cancer cells? Question 101. Is cell migration a selectable trait in the natural evolution of carcinoma?

Until now, the battle against cancer is still ongoing, but there are also ongoing discoveries being made. Milestones in cancer research and treatments are being achieved every year; at a quicker pace, as compared to decades ago. Likewise, some cancers that were considered incurable are now partly curable, lives that could not be saved are now being saved, and for those with yet little options, they are now having best-supporting care. With an objective to promote worldwide cancer research and even accelerate inter-countries collaborations, since the beginning of 2017, Cancer Communications (former title: Chinese Journal of Cancer ) has launched a program of publishing 150 most important questions in cancer research and clinical oncology [ 1 ]. We are providing a platform for researchers to freely voice-out their novel ideas, and propositions to enhance the communications on how and where our focus should be placed [ 2 , 3 , 4 , 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 ]. In this edition, 8 valuable and inspiring questions, Question 94–101, from highly distinguished professionals from different parts of the world are presented. If you have any novel proposition(s) and Question(s), please feel free to contact Ms. Ji Ruan via email: [email protected].

Question 94: The origin of tumors: time for a new paradigm?

Background and implications.

“There is no worse blind man than the one who doesn’t want to see. There is no worse deaf man than the one who doesn’t want to hear. And there is no worse madman than the one who doesn’t want to understand.” —Ancient Proverb

In the past half-century, cancer biologists have focused on a dogma in which cancer was viewed as a proliferative disease due to mechanisms that activate genes (oncogenes) to promote cell proliferation or inactivate genes (tumor suppressor genes) to suppress tumor growth. In retrospect, these concepts were established based on functional selections, by using tissue culture (largely mouse NIH 3T3 cells) for the selection of transformed foci at the time when we knew virtually nothing about the human genome [ 14 ]. However, it is very difficult to use these genes individually or in combinations to transform primary human cells. Further, the simplified view of uncontrolled proliferation cannot explain the tumor as being a malignant organ or a teratoma, as observed by pathologists over centuries. Recently, the cancer genomic atlas project has revealed a wide variety of genetic alterations ranging from no mutation to multiple chromosomal deletions or fragmentations, which make the identification of cancer driver mutations very challenging in a background of such a massive genomic rearrangement. Paradoxically, this increase the evidences demonstrating that the oncogenic mutations are commonly found in many normal tissues, further challenging the dogma that genetic alteration is the primary driver of this disease.

Logically, the birth of a tumor should undergo an embryonic-like development at the beginning, similar to that of a human. However, the nature of such somatic-derived early embryo has been elusive. Recently, we provided evidence to show that polyploid giant cancer cells (PGCCs), which have been previously considered non-dividing, are actually capable of self-renewal, generating viable daughter cells via amitotic budding, splitting and burst, and capable of acquisition of embryonic-like stemness [ 15 , 16 , 17 ]. The mode of PGCC division is remarkably similar to that of blastomere, a first step in human embryogenesis following fertilization. The blastomere nucleus continuously divides 4–5 times without cytoplasmic division to generate 16–32 cells and then to form compaction/morulae before developing into a blastocyst [ 18 ]. Based on these data and similarity to the earliest stage of human embryogenesis, I propose a new theory that tumor initiation can be achieved via a dualistic origin, similar to the first step of human embryogenesis via the formation of blastomere-like cells, i.e. the activation of blastomere or blastomere-like cells which leads to the dedifferentiation of germ cells or somatic cells, respectively, which is then followed by the differentiation to generate their respective stem cells, and the differentiation arrest at a specific developmental hierarchy leading to tumor initiation [ 19 ]. The somatic-derived blastomere-like cancer stem cell follows its own mode of cell growth and division and is named as the giant cell cycle. This cycle includes four distinct but overlapping phases: the initiation, self-renewal, termination, and stability phases. The giant cell cycle can be tracked in vitro and in vivo due to their salient giant cell morphology (Fig.  1 ).

One mononucleated polyploid giant cancer cell (PGCC) in the background of regular size diploid cancer cells. The PGCC can be seen to be at least 100 times larger than that of regular cancer cells

This new theory challenges the traditional paradigm that cancer is a proliferative disease, and proposes that the initiation of cancer requires blastomere-like division that is similar to that of humans before achieving stable proliferation at specific developmental hierarchy in at least half of all human cancers. This question calls for all investigators in the cancer research community to investigate the role of PGCCs in the initiation, progression, resistance, and metastasis of cancer and to look for novel agents to block the different stages of the giant cell cycle.

The histopathology (phenotype) of cancers has been there all the time. It is just the theory of cancer origin proposed by scientists that changes from time to time. After all, trillions of dollars have been invested in fighting this disease by basing on its genetic origin in the past half-century, yet, little insight has been gained [ 14 ]. Here are two quotes from Einstein: “Insanity: doing the same thing over and over again expecting different results”, and “We cannot solve our problems with the same thinking we used when created them”.

In short, it is time to change our mindset and to start pursuing PGCCs, which we can observe under the microscope. But with very little understanding about these cells, it is time for a shift in paradigm.

Jinsong Liu.

Affiliation

Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030-4095, USA.

Email address

[email protected]

Question 95: How can we accelerate the identification of biomarkers for the early detection of pancreatic ductal adenocarcinoma?

Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal cancers in the world with a dismal 5-year overall survival rate of less than 5%; which has not been significantly improved since the past decades. Although surgical resection is the only option for curative treatment of PDAC, only 15%–20% of patients with PDAC have the chance to undergo curative resection, leaving the rest with only palliative options in hope for increasing their quality of life; since they were already at unresectable and non-curative stages at their first diagnosis.

The lack of specific symptoms in the early-stage of PDAC is responsible for rendering an early diagnosis difficult. Therefore, more sensitive and specific screening methodologies for its early detection is urgently needed to improve its diagnosis, starting early treatments, and ameliorating prognoses. The diagnosis so far relies on imaging modalities such as abdominal ultrasound, computed tomography (CT), magnetic resonance imaging (MRI), endoscopic ultrasound (EUS), endoscopic retrograde cholangiopancreatography (ERCP), and positron emission tomography (PET). One may propose to screen for pancreatic cancer in high-risk populations, which is highly recommended, however screening intervention for all the people is not a wise choice; when considering the relatively low prevalence of PDAC, and the difficulty for diagnosing it in its early stage [ 20 ].

Therefore, alternative diagnostic tools for early detection of PDAC are highly expected. Among the biomarkers currently used in clinical practice, carbohydrate antigen 19–9 (CA19–9) is among the most useful one for supporting the diagnosis of PDAC, but it is neither sufficiently sensitive nor specific for its early detection. Yachida et al. reported in 2010 that the initiating mutation in the pancreas occurs approximately two decades before the PDAC to start growing in distant organs [ 21 ], which indicates a broad time of the window of opportunity for the early detection of PDAC. With the advancement in next-generation sequencing technology, the number of reported studies regarding novel potential molecular biomarkers in bodily fluids including the blood, feces, urine, saliva, and pancreatic juice for early detection of PDAC has been increasing. Such biomarkers may be susceptible to detect mutations at the genetic or epigenetic level, identifying important non-coding RNA (especially microRNA and long non-coding RNA), providing insights regarding the metabolic profiles, estimating the tumor level in liquid biopsies (circulating free DNA, circulating tumor cells and exosomes), and so on.

Another approach to identifying biomarkers for the early detection of pancreatic cancer is using animal models. In spontaneous animal models of pancreatic cancer, such as Kras-mutated mouse models, it is expected that by high throughput analyses of the genetic/epigenetic/proteomic alterations, some novel biomarkers might be able to be identified. For instance, Sharma et al. reported in 2017 that the detection of phosphatidylserine-positive exosomes enabled the diagnosis of early-stage malignancies in LSL-Kras G12D , Cdkn2a lox/lox : p48 Cre and LSL-Kras G12d/+ , LSL-Trp R172H/+ , and P48 Cre mice [ 22 ].

These analyses in clinical samples or animal models hold the clues for the early detection of PDAC, however, further studies are required to validate their diagnostic performance. What’s most important, will be the lining-up of these identified prospective biomarkers, to validate their sensitivities and specificities. This will determine their potential for widespread clinical applicability, and hopefully, accelerate the early diagnosis of PDAC.

Mikiya Takao 1,2 , Hirotaka Matsuo 2 , Junji Yamamoto 1 , and Nariyoshi Shinomiya 2 .

1 Department of Surgery, National Defense Medical College, 3-2 Namiki, Tokorozawa, Saitama 359-8513, Japan; 2 Department of Integrative Physiology and Bio-Nano Medicine, National Defense Medical College, 3-2 Namiki, Tokorozawa, Saitama 359-8513, Japan.

E-mail address

[email protected]; [email protected]; [email protected]; [email protected]

Question 96: Can we improve the treatment outcomes of metastatic pancreatic ductal adenocarcinoma through precision medicine guided by a combination of the genetic and proteomic information of the tumor?

Pancreatic ductal adenocarcinoma (PDAC) is one of the most malignant cancers, and nearly half of the patients had metastatic PDAC when they are initially diagnosed. When they are accompanied by metastatic tumors, unlike most solid cancer, PDAC cannot be cured with primary surgical resection alone [ 23 , 24 ]. Also, since PDAC has poor responses to conventional therapies, improvements in adjunctive treatment approach including chemo- and immuno-therapy are earnestly required. From this standpoint, recent results regarding the differences in the molecular evolution of pancreatic cancer subtypes provide a new insight into its therapeutic development [ 25 ], which may lead to the improvement of the prognosis of not only metastatic PDAC but also of locally advanced or recurrent PDAC.

In fact, new chemotherapeutic regimens such as the combination of gemcitabine with nab-paclitaxel and FOLFIRINOX have been reported to show improved prognosis despite a lack of examples of past successes in the treatment of patients with metastatic PDAC who had undergone R0 resection [ 26 ]. While many mutations including KRAS , CDKN2A , TP53, and SMAD4 are associated with pancreatic carcinogenesis, no effective molecular targeted drug has been introduced in the clinical setting so far. A recent report of a phase I/II study on refametinib, a MEK inhibitor, indicated that KRAS mutation status might affect the overall response rate, disease control rate, progression-free survival, and overall survival of PDAC in combination with gemcitabine [ 27 ].

While immunotherapy is expected to bring a great improvement in cancer treatment, until now, immune checkpoint inhibitors have achieved limited clinical benefit for patients with PDAC. This might be because PDAC creates a uniquely immunosuppressive tumor microenvironment, where tumor-associated immunosuppressive cells and accompanying desmoplastic stroma prevent the tumor cells from T cell infiltration. Recently reported studies have indicated that immunotherapy might be effective when combined with focal adhesion kinase (FAK) inhibitor [ 28 ] or IL-6 inhibitor [ 29 ], but more studies are required to validate their use in clinical practice.

As such, we believe that if the dynamic monitoring of drug sensitivity/resistance in the individual patients is coupled with precision treatment based on individualized genetics/epigenetics/proteomics alterations in the patients’ tumor, this could improve the treatment outcomes of PDAC.

Mikiya Takao 1,2 , Hirotaka Matsuo 2 , Junji Yamamoto 1 , and Nariyoshi Shinomiya 2.

Question 97: What are the parameters that determine a competent immune system that gives a complete response to cancers after immune induction?

Recently, cancer immunotherapy has shown great clinical benefit in multiple types of cancers [ 30 , 31 , 32 ]. It has provided new approaches for cancer treatment. However, it has been observed that only a fraction of patients respond to immunotherapy.

Much effort has been made to identify markers for immunotherapeutic response. Tumor mutation burden (TMB), mismatch repair (MMR) deficiency, PD-L1 expression, and tumor infiltration lymphocyte (TIL) have been found to be associated with an increased response rate in checkpoint blockade therapies. Unfortunately, a precise prediction is still challenging in this field. Moreover, when to stop the treatment of immunotherapy is an urgent question that remains to be elucidated.

In other words, there is no available approach to determine if a patient has generated a good immune response against the cancer after immunotherapy treatments. All of these indicate the complexity and challenges that reside for implementing novel man-induced cancer-effective immune response therapeutics. A variety of immune cells play collaborative roles at different stages to recognize antigens and eventually to generate an effective anti-cancer immune response. Given the high complexity of the immune system, a rational evaluation approach is needed to cover the whole process. Moreover, we need to perfect vaccine immunization and/or in vitro activation of T cells to augment the function of the immune system; particularly the formation of immune memory.

Edison Liu 1 , Penghui Zhou 2 , Jiang Li 2 .

1 The Jackson Laboratory, Bar Harbor, ME 04609, USA; 2 Sun Yat-sen University Cancer Center, Guangzhou, Guangdong 510060, P. R. China.

[email protected]; [email protected]; [email protected]

Question 98: Is high local concentration of metformin essential for its anti-cancer activity?

Metformin was approved as a first line of anti-diabetic drug since decades. Interestingly, the fact that clinical epidemiological studies have shown that metformin can reduce the risk of a variety of cancers stimulates considerable recognition to explore its anticancer activity.

Although the in vitro and in vivo experimental results have demonstrated that metformin can have some potential anti-tumor effects, more than 100 clinical trials did not achieve such desirable results [ 33 ]. We and others believe that the main problem resides in the prescribing doses used. For cancer treatment, a much higher dose may be needed for observing any anti-tumor activities, as compared to the doses prescribed for diabetics [ 34 , 35 , 36 ].

Further, if the traditional local/oral administration approach is favored, the prescribed metformin may not be at the required dose-concentration once it reaches the blood to have the effective anti-cancer activities. We, therefore, propose that intravesical instillation of metformin into the bladder lumen could be a promising way to treat for bladder cancer, at least. We have already obtained encouraging results both in vitro and in vivo experiments, including in an orthotopical bladder cancer model [ 36 , 37 ]. Now, we are waiting to observe its prospective clinical outcome.

Mei Peng 1 , Xiaoping Yang 2 .

1 Department of Pharmacy, Xiangya Hospital, Central South University. Changsha, Hunan 410083, P. R. China; 2 Key Laboratory of Study and Discovery of Small Targeted Molecules of Hunan Province, Department of Pharmacy, School of Medicine, Hunan Normal University, Changsha, Hunan 410013, P. R. China.

[email protected]; [email protected]

Question 99: How can we monitor the emergence of cancer cells anywhere in the body through plasma testing?

The early detection of cancer is still a relentless worldwide challenge. The sensitivity and specificity of traditional blood tumor markers and imaging technologies are still to be greatly improved. Hence, novel approaches for the early detection of cancer are urgently needed.

The emergence of liquid biopsy technologies opens a new driveway for solving such issues. According to the definition of the National Cancer Institute of the United States, a liquid biopsy is a test done on a sample of blood to look for tumorigenic cancer cells or pieces of tumor cells’ DNA that are circulating in the blood [ 38 ]. This definition implies two main types of the current liquid biopsy: one that detects circulating tumor cells and the other that detects non-cellular material in the blood, including tumor DNA, RNA, and exosomes.

Circulating tumor cells (CTCs) are referred to as tumor cells that have been shed from the primary tumor location and have found their way to the peripheral blood. CTCs were first described in 1869 by an Australian pathologist, Thomas Ashworth, in a patient with metastatic cancer [ 39 ]. The importance of CTCs in modern cancer research began in the mid-1990s with the demonstration that CTCs exist early in the course of the disease.

It is estimated that there are about 1–10 CTCs per mL in whole blood of patients with metastatic cancer, even fewer in patients with early-stage cancer [ 40 ]. For comparison, 1 mL of blood contains a few million white blood cells and a billion erythrocytes. The identification of CTCs, being in such low frequency, requires some special tumoral markers (e.g., EpCAM and cytokeratins) to capture and isolate them. Unfortunately, the common markers for recognizing the majority of CTCs are not effective enough for clinical application [ 41 ]. Although accumulated evidences have shown that the presence of CTCs is a strong negative prognostic factor in the patients with metastatic breast, lung and colorectal cancers, detecting CTCs might not be an ideal branch to hold on for the hope of early cancer detection [ 42 , 43 , 44 , 45 ].

Circulating tumor DNA (ctDNA) is tumor-derived fragmented DNA in the circulatory system, which is mainly derived from the tumor cell death through necrosis and/or apoptosis [ 46 ]. Given its origin, ctDNA inherently carries cancer-specific genetic and epigenetic aberrations, which can be used as a surrogate source of tumor DNA for cancer diagnosis and prognostic prediction. Ideally, as a noninvasive tumor early screening tool, a liquid biopsy test should be able to detect many types of cancers and provide the information of tumor origin for further specific clinical management. In fact, the somatic mutations of ctDNA in different types of tumor are highly variable, even in the different individuals with the same type of tumor [ 47 ]. Additionally, most tumors do not possess driver mutations, with some notable exceptions, which make the somatic mutations of ctDNA not suitable for early detection of the tumor.

Increased methylation of the promoter regions of tumor suppressor genes is an early event in many types of tumor, suggesting that altered ctDNA methylation patterns could be one of the first detectable neoplastic changes associated with tumorigenesis [ 48 ]. ctDNA methylation profiling provides several advantages over somatic mutation analysis for cancer detection including higher clinical sensitivity and dynamic range, multiple detectable methylation target regions, and multiple altered CpG sites within each targeted genomic region. Further, each methylation marker is present in both cancer tissue and ctDNA, whereas only a fraction of mutations present in cancer tissue could be detected in ctDNA.

In 2017, there were two inspiring studies that revealed the values of using ctDNA methylation analysis for cancer early diagnosis [ 49 , 50 ]. After partitioning the human genome into blocks of tightly coupled CpG methylation sites, namely methylation haplotype blocks (MHBs), Guo and colleagues performed tissue-specific methylation analyses at the MHBs level to accurately determine the tissue origin of the cancer using ctDNA from their enrolled patients [ 49 ]. In another study, Xu and colleagues identified a hepatocellular carcinoma (HCC) enriched methylation marker panel by comparing the HCC tissue and blood leukocytes from normal individuals and showed that methylation profiles of HCC tumor DNA and matched plasma ctDNA were highly correlated. In this study, after quantitative measurement of the methylation level of candidate markers in ctDNA from a large cohort of 1098 HCC patients and 835 normal controls, ten methylation markers were selected to construct a diagnostic prediction model. The proposed model demonstrated a high diagnostic specificity and sensitivity, and was highly correlated with tumor burden, treatment response, and tumor stage [ 50 ].

With the rapid development of highly sensitive detection methods, especially the technologies of massively parallel sequencing or next-generation sequencing (NGS)-based assays and digital PCR (dPCR), we strongly believe that the identification of a broader “pan-cancer” methylation panel applied for ctDNA analyses, probably in combination with detections of somatic mutation and tumor-derived exosomes, would allow more effective screening for common cancers in the near future.

Edison Liu 1 , Hui-Yan Luo 2 .

[email protected]; [email protected]

Question 100: Can phytochemicals be more specific and efficient at targeting P-glycoproteins to overcome multi-drug resistance in cancer cells?

Though several anticancer agents are approved to treat different types of cancers, their full potentials have been limited due to the occurrence of drug resistance. Resistance to anticancer drugs develops by a variety of mechanisms, one of which is increased drug efflux by transporters. The ATP-binding cassette (ABC) family drug efflux transporter P-glycoprotein (P-gp or multi-drug resistance protein 1 [MDRP1]) has been extensively studied and is known to play a major role in the development of multi-drug resistance (MDR) to chemotherapy [ 51 ]. In brief, overexpressed P-gp efflux out a wide variety of anticancer agents (e.g.: vinca alkaloids, doxorubicin, paclitaxel, etc.), leading to a lower concentration of these drugs inside cancer cells, thereby resulting in MDR. Over the past three decades, researchers have developed several synthetic P-gp inhibitors to block the efflux of anticancer drugs and have tested them in clinical trials, in combination with chemotherapeutic drugs. But none were found to be suitable enough in overcoming MDR and to be released for marketing, mainly due to the side effects associated with cross-reactivity towards other ABC transporters (BCRP and MRP-1) and the inhibition of CYP450 drug metabolizing enzymes [ 52 , 53 ].

On the other hand, a number of phytochemicals have been reported to have P-gp inhibitory activity. Moreover, detailed structure–activity studies on these phytochemicals have delineated the functional groups essential for P-gp inhibition [ 53 , 54 ]. Currently, one of the phytochemicals, tetrandrine (CBT-1 ® ; NSC-77037), is being used in a Phase I clinical trial ( http://www.ClinicalTrials.gov ; NCT03002805) in combination with doxorubicin for the treatment of metastatic sarcoma. Before developing phytochemicals or their derivatives as P-gp inhibitors, they need to be investigated thoroughly for their cross-reactivity towards other ABC transporters and CYP450 inhibition, in order to avoid toxicities similar to the older generation P-gp inhibitors that have failed in clinical trials.

Therefore, the selectivity for P-gp over other drug transporters and drug metabolizing enzymes should be considered as important criterias for the development of phytochemicals and their derivatives for overcoming MDR.

Mohane Selvaraj Coumar and Safiulla Basha Syed.

Centre for Bioinformatics, School of Life Sciences, Pondicherry University, Kalapet, Puducherry 605014, India.

[email protected]; [email protected]

Question 101: Is cell migration a selectable trait in the natural evolution of carcinoma?

The propensity of solid tumor malignancy to metastasize remains the main cause of cancer-related death, an extraordinary unmet clinical need, and an unanswered question in basic cancer research. While dissemination has been traditionally viewed as a late process in the progression of malignant tumors, amount of evidence indicates that it can occur early in the natural history of cancer, frequently when the primary lesion is still barely detectable.

A prerequisite for cancer dissemination is the acquisition of migratory/invasive properties. However, whether, and if so, how the migratory phenotype is selected for during the natural evolution of cancer and what advantage, if any, it may provide to the growing malignant cells remains an open issue. The answers to these questions are relevant not only for our understating of cancer biology but also for the strategies we adopt in an attempt of curbing this disease. Frequently, indeed, particularly in pharmaceutical settings, targeting migration has been considered much like trying “to shut the stable door after the horse has bolted” and no serious efforts in pursuing this aim has been done.

We argue, instead, that migration might be an intrinsic cancer trait that much like proliferation or increased survival confers to the growing tumor masses with striking selective advantages. The most compelling evidence in support for this contention stems from studies using mathematical modeling of cancer evolution. Surprisingly, these works highlighted the notion that cell migration is an intrinsic, selectable property of malignant cells, so intimately intertwined with more obvious evolutionarily-driven cancer traits to directly impact not only on the potential of malignant cells to disseminate but also on their growth dynamics, and ultimately provide a selective evolutionary advantage. Whether in real life this holds true remains to be assessed, nevertheless, work of this kind defines a framework where the acquisition of migration can be understood in a term of not just as a way to spread, but also to trigger the emergence of malignant clones with favorable genetic or epigenetic traits.

Alternatively, migratory phenotypes might emerge as a response to unfavorable conditions, including the mechanically challenging environment which tumors, and particularly epithelial-derived carcinoma, invariably experience. Becoming motile, however, may not per se being fixed as phenotypic advantageous traits unless it is accompanied or is causing the emergence of specific traits, including drug resistance, self-renewal, and survival. This might be the case, for example, during the process of epithelial-to-mesenchymal transition (EMT), which is emerging as an overarching mechanism for dissemination. EMT, indeed, may transiently equip individual cancer cells not only with migratory/invasive capacity but also with increased resistance to drug treatment, stemness potential at the expanse of fast proliferation.

Thus, within this framework targeting pro-migratory genes, proteins and processes may become a therapeutically valid alternative or a complementary strategy not only to control carcinoma dissemination but also its progression and development.

Giorgio Scita.

IFOM, The FIRC Institute of Molecular Oncology, Via Adamello 16, 20139 Milan, Italy; Department of Oncology and Hemato-Oncology (DIPO), School of Medicine, University of Milan, Via Festa del Perdono 7, 20122, Italy.

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Teaching Medical Research to Medical Students: a Systematic Review

Gabriel sheng jie lee.

1 Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore

Yip Han Chin

Aimei amy jiang, cheng han mg, kameswara rishi yeshayahu nistala, shridhar ganpathi iyer.

2 Division of Hepatobiliary & Pancreatic Surgery, Department of Surgery, National University Hospital, Singapore, Singapore

3 Liver Transplantation, National University Centre for Organ Transplantation, National University Hospital, Singapore, Singapore

Shuh Shing Lee

4 Centre for Medical Education, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore

Choon Seng Chong

5 Division of Colorectal Surgery, Department of Surgery, National University Hospital, 1E Kent Ridge Road, Singapore, 119228 Singapore

Dujeepa D. Samarasekera

Associated data.

Research literacy remains important for equipping clinicians with the analytical skills to tackle an ever-evolving medical landscape and maintain an evidence-based approach when treating patients. While the role of research in medical education has been justified and established, the nuances involving modes of instruction and relevant outcomes for students have yet to be analyzed. Institutions acknowledge an increasing need to dedicate time and resources towards educating medical undergraduates on research but have individually implemented different pedagogies over differing lengths of time.

While individual studies have evaluated the efficacy of these curricula, the evaluations of educational methods and curriculum design have not been reviewed systematically. This study thereby aims to perform a systematic review of studies incorporating research into the undergraduate medical curriculum, to provide insights on various pedagogies utilized to educate medical students on research.

Studies predominantly described two major components of research curricula—(1) imparting basic research skills and the (2) longitudinal application of research skills. Studies were assessed according to the 4-level Kirkpatrick model for evaluation. Programs that spanned minimally an academic year had the greatest proportion of level 3 outcomes (50%). One study observed a level 4 outcome by assessing the post-intervention effects on participants. Studies primarily highlighted a shortage of time (53%), resulting in inadequate coverage of content.

This study highlighted the value in long-term programs that support students in acquiring research skills, by providing appropriate mentors, resources, and guidance to facilitate their learning. The Dreyfus model of skill acquisition underscored the importance of tailoring educational interventions to allow students with varying experience to develop their skills. There is still room for further investigation of multiple factors such as duration of intervention, student voluntariness, and participants’ prior research experience. Nevertheless, it stands that mentoring is a crucial aspect of curricula that has allowed studies to achieve level 3 Kirkpatrick outcomes and engender enduring changes in students.

Supplementary Information

The online version contains supplementary material available at 10.1007/s40670-020-01183-w.

Introduction

Medical research is of high value to clinicians and society. In modern-day practice, the continued growth of knowledge has added richness to the medical world and challenges medical professionals to stay afloat. As such, to navigate the ever-evolving advances in medical practice and technology, literacy in research remains crucial for the effective application of evidence-based medicine. In particular, medical research equips clinicians with skills to critically analyze the clinical relevance of papers to provide invaluable insights into novel treatments.

The integration of research into medical education has been documented to have translated into skills valuable to future clinical practice. Exposure to research experiences may improve analytical reasoning, communication skills, and application of emerging knowledge to patient care [ 1 ]. This may serve to benefit students as future medical practitioners. Early exposure to research experience as medical students may also enhance the relevance of research in routine practice as doctors and has shown to be associated with future postgraduate research involvement [ 2 ]. Lastly, integration of research into medical curricula may provide students with a suitable foundation on which they can further develop their skills as required in their careers [ 3 ].

Yet, despite the growing appreciation of research, the participation of medical students in research remains limited. Most students entering medical school are neither aware of how scientific research functions nor cognizant of its importance [ 4 ]. Research by Stone et al. showed that the motivations fueling students’ research interests include competing for residency and enhancing resumes, amongst others related to career advancement [ 5 ]. With the goal of research being the improvement of evidence-based practice and bench to bedside translational research, such motivations may seem almost perverse [ 5 ]. Furthermore, there are barriers within medical education systems that further hinder students’ exposure and participation in research. Medical students are deterred by the practical difficulties such as the lack of learning opportunities [ 6 ], and challenges in securing research-associated opportunities, particularly if they lack relevant skills [ 1 ]. Burgoyne et al. also found that over half of all medical students are interested in a career incorporating medical research [ 3 ]. Nevertheless, they remain largely unaware of such activities in their host institution due to gaps in the curricula [ 3 ], with even residents finding difficulties in completing research projects [ 7 ]. With the myriad of benefits that medical research can bring, it is therefore important to embrace research as an integral part of the undergraduate medical curriculum, and effectively integrate it into the curriculum.

Currently, studies discussing the effectiveness of imparting research skills to medical students in professional degree programs are available. However, a synthesis of these results has yet to be undertaken. The role of human medical research in medical education has been justified and established, but the nuances involving modes of instruction and relevant outcomes for undergraduate medical students have yet to be analyzed. This study thereby aims to perform a systematic review of studies incorporating research into the undergraduate medical curriculum, to provide insights on various pedagogies utilized to educate medical students on research.

Materials and Methods

Database sources.

In consultation with a medical librarian, three major electronic databases, MEDLINE, CINAHL, and Web of Science, were searched for articles related to educating students about research from inception until January 2020. With advice from a medical librarian, key search terms such as “medical students” and “research methodology” were applied in the search. The search strategy used can be found in the supplementary materials.

Article Selection and Eligibility Criteria

English articles that evaluated an intervention or existing programs educating medical students about research were included in this review. Medical students were defined in this study as students in a professional medical degree program (postgraduate or undergraduate studies), limited to the human medical field (veterinary field, dentistry, or nursing were excluded). Only primary research articles with the above criteria were considered—all opinions, reviews, commentary, or editorial papers were excluded. A two-stage process of selection was employed, where two authors independently screened through titles and abstracts to select articles according to the eligibility criteria. Thereafter, a full-text sieve was conducted, and articles were excluded based on the eligibility criteria.

Data Extraction and Synthesis

Two independent authors extracted the following data from the included articles: publication details, study sample demographics (year of study, sample size, research experience), and intervention details (curriculum design, frequency of sessions, mode of teaching). The data coded was then grouped into subcategories described by the included studies and captured the unique observations and perspectives of the pooled data.

While several methods are available for the synthesis of such knowledge [ 8 ], this study focused on emphasizing the relationship between time and resources invested in holistically increasing medical students’ research capabilities, and thus used directed content analysis and deductive theming [ 9 , 10 ]. For outcome measures, the Kirkpatrick model was used [ 11 ]. The Kirkpatrick model consists of four levels: reactions, learning, behaviors, and results of training participants. Specific to research education, level 1 measures participants’ self-reported changes in attitude and interest in research, while level 2 measures objective knowledge retention. Level 3 records changes in participant’s behaviors through increased research productivity and level 4 observes quantifiable outcomes and results beyond the education program such as an enduring active engagement in research [ 11 ]. Thereafter, the data was synthesized and grouped into major categories, according to pedagogy, assessment methods, and outcomes achieved. Any discrepancies were discussed and resolved in consensus or in consultation with a third author.

Quality Appraisal of Included Studies

Quality appraisal was conducted with the Medical Education Research Study Quality Instrument (MERSQI) designed to evaluate systematic reviews of education research. MERSQI is a 10-item instrument that grades studies on 6 domains: study design, sampling, type of data, validity of evidence, data analysis, and type of outcomes [ 12 ]. Two authors independently appraised the articles and resolved discrepancies via consensus or in consultation with a third author.

Through database searches, 3573 articles were identified. Thereafter, 157 full-text articles were assessed, and a total 35 articles were included in this paper (Fig. 1 ). Sample size ranged from 11 to 916 (mean = 148) and a total of 5182 students participated in the included studies. Twenty-one studies (60%) were conducted in North America while the remaining studies were conducted in Africa, Asia, Australia, and Europe. One study recruited participants from multiple European countries [ 13 ]. Participants were most often students in their pre-clinical years ( n  = 16, 46%), with six studies reporting prior research experience, and three studies reporting no prior research experience [ 14 – 16 ]. The remaining 26 studies did not report students’ prior research experience. Additionally, 19 studies involved voluntary elective educational interventions, while the other 16 studies observed enforced curricular interventions. Twenty-two articles were quantitative studies, 2 were qualitative, and 11 were mixed method studies. Table ​ Table1 1 summarizes the data of the included articles. Quality assessment was done, and most articles scored 10 and above according to MERSQI, details of the scoring can be seen in Table ​ Table1 1 .

PRISMA flowchart

Summary of included articles

The studies predominantly described two major components of research curricula—(1) imparting basic research skills to students and (2) longitudinal application of research skills. These components were used exclusively by 17 studies and combined into a multimodal approach by 18 studies. Most curricula incorporated a mentorship program ( n  = 28, 80%) to expose students to medical research. Didactic teachings were the next most common method ( n  = 22, 62%). Other methods include small group discussions, e-learning methods, and seminars. Interventions generally occurred over the academic year ( n  = 12, 34%), over the summer break ( n  = 12, 34%), over multiple years ( n  = 6, 17%), or as workshops lasting one to seven days ( n  = 5, 14%). A detailed breakdown of the education curriculum is provided in Table ​ Table2 2 .

Important characteristics of articles evaluating research education to medical students

a Individual studies employed multiple modalities of interventions, leading to percentages adding to greater than 100

b Study employed a mentored research program but did not specify occupation of mentor (peer, faculty member, or otherwise)

c Symposium style

d Self-conducted research

e The extent to which students reacted positively to the curricula, such as enjoyable content, comfortable learning experience, and effective teaching style

f The extent to which students have developed the expertise, knowledge, and skills needed to conduct research. These skills and knowledge were evaluated through increased tests used to measure the students content knowledge

g The extent to which students behavior has changed after completing the education curricula provided by the various schools/organizations. This is evaluated through increased research output through the curricula program

h The extent of success of the curricula in quantifiable factors such as increased rate of research articles published by the school due to students own initiative and not during the term of the curricula

Educational modalities were focused on two main goals. Firstly, studies described curricula designed to teach basic research skills such as formulating research questions and developing study designs [ 17 – 19 ]. The duration of curricula was generally one to seven days [ 20 ], after which participants could also express their interest in research projects [ 15 ]. Secondly, studies aimed to provide students an opportunity to apply their acquired research skills through the completion of a research project, primarily under the supervision of a mentor [ 13 , 15 , 17 – 19 , 21 – 42 ]. Broadly, studies utilized both methods in tandem, while some studies exclusively employed either method.

Basic Research Skills Curricula

Curricula utilized didactic teaching strategies to impart basic skills to students as an introductory course to research. These courses encompassed topics such as experimental design, research methodology, interpretation of experimental data [ 43 ], and statistical analysis [ 16 , 18 , 19 , 25 , 35 ]. Apart from formal didactic sessions, studies also included seminars ( n  = 4, 11%) [ 25 , 30 , 32 , 40 ], e-learning modules ( n  = 4, 11%) [ 37 , 40 , 44 , 45 ], and small group discussion sessions ( n  = 3, 9%) to equip students with research skills [ 23 , 32 , 36 ].

Longitudinal Application of Research Skills

Curricula also incorporated longitudinal mentored research experiences to expose students to research (Table ​ (Table2). 2 ). Students were assigned to mentors from a range of faculties and clinical settings, and were guided through basic biomedical, epidemiological, and community-health-related research projects [ 13 , 19 , 22 , 23 , 33 , 34 , 38 , 41 , 42 , 46 ]. These studies recruited faculty or community research mentors [ 13 , 19 , 22 , 23 , 30 , 31 , 33 , 34 , 38 , 39 , 42 ], with one study recruiting additional peer mentors ( n  = 1, 10%) with prior research experience to guide students [ 22 ].

A Multimodal Approach

Studies in this review predominantly adopted a multimodal approach ( n  = 18, 51.4%), involving both elements of didactic teaching as well as mentorship. Studies included initial classroom instruction on the theoretical aspects of research, followed by a period of practical application under the guidance of mentors [ 13 , 15 , 17 , 18 , 21 , 24 – 29 , 32 , 35 – 37 ]. Apart from incorporating the components mentioned above, such programs conventionally lasted the duration of a summer break [ 17 – 19 , 22 , 23 , 25 , 26 , 29 , 34 , 41 – 43 ], an academic year [ 14 , 21 , 24 , 27 , 28 , 31 , 32 , 36 – 38 , 40 , 45 ], or extended to multiple academic years [ 13 , 16 , 21 , 30 , 33 , 39 ].

Assessment Methods

To analyze the impact of didactic curricula and longitudinal research experiences on participants, a majority of the studies utilized pre- and post-surveys ( n  = 27, 77%) to gather both qualitative and quantitative participant feedback [ 14 – 18 , 20 , 22 – 24 , 26 – 32 , 35 – 37 , 39 – 41 , 43 – 45 , 47 , 48 ]. Students’ feedback was collated via qualitative questionnaires [ 39 ], feedback sessions [ 30 ], and Likert scale-type questions to measure their satisfaction with the curricula and interest levels in research [ 47 ].

Studies primarily used knowledge tests to determine the benefits of didactic curricula of students. Evaluation conducted by studies included pre- and post-quizzes (Table ​ (Table2), 2 ), in the form of multiple-choice questions to measure students’ retention of knowledge [ 28 , 47 ]. Quizzes comprised internally developed components and externally sourced questions adapted for institutions’ local contexts [ 44 ]. Studies also established student’s understanding of learning objectives through self-reported scores on closed-ended questionnaires [ 20 ].

Studies also evaluated the research output of students who undertook mentored research projects to assess the effectiveness of the curricula. The number of publications ( n  = 4, 40%) was used as a quantitative marker for effectiveness (Table ​ (Table2). 2 ). Additionally, studies also noted the number of student submissions for conference presentations. Participants were also assessed on their application of research skills via written and oral presentations of their research proposals to the faculty [ 24 ].

Studies that delivered research education through both modalities attempted to evaluate students on both theoretical and practical fronts. Studies developed questionnaires on research methodology and other practices surrounding information literacy to quantitatively assess students’ gain in knowledge [ 28 ]. Studies also monitored the number of students engaged in research beyond the program as well as the frequency of successful presentations and publications [ 25 ].

Level 1 outcomes centered around participants’ self-reported changes in behavior, knowledge, interest in research, and feedback towards the course. Students’ responses to the curricula were overwhelmingly positive [ 36 ]. Students found that research curricula were relevant, interesting, and improved their knowledge and research skills [ 48 ]. Next, studies evaluated level 2 outcomes by assessing the degree to which participants have gained knowledge and skills from curricula [ 16 , 28 , 37 , 44 , 47 , 48 ]. Studies reported significant increases in pre- and post-test results which encompassed both research skills and medical knowledge [ 16 , 42 ].

Curricula exclusively comprised of didactic teaching methods were often not able to produce level 3 outcomes. Two studies were able to observe completed research projects [ 48 ], out of which only one study gave rise to a 0.47% rate of publications produced per student [ 16 ].

Studies describing longitudinal research curricula also recorded level 1 outcomes, primarily in the form of students’ feedback. Participant feedback was uniformly enthusiastic [ 18 ], and participants reported significant increases in knowledge from their baseline to post-intervention [ 29 ]. Studies observed that students better understood the integral place of research in a physician’s role and were more motivated towards careers in specialties they were exposed to [ 13 , 23 ]. In terms of level 2 outcomes, studies revealed that the research curriculum facilitated the acquisition of research-related knowledge amongst students [ 28 , 48 ]. Students showed significant improvements between pre- and post-intervention knowledge quizzes and also reported significantly higher median scores for research items on tests [ 37 ].

Students were able to achieve level 3 outcomes when curricula required students to undertake a research project. Both interventions employing peer mentors ( n  = 2/2, 100%) and researcher mentors ( n  = 16//26, 62%) were shown to produce level 3 outcomes [ 15 , 17 , 21 , 22 , 25 , 27 – 29 , 32 – 37 , 40 , 42 ]. The duration of the educational interventions also had a substantial effect on the ability to achieve level 3 outcomes. Programs that spanned at least a single academic year had the greatest proportion of level 3 outcomes ( n  = 9, 50%) [ 16 , 21 , 27 , 28 , 32 , 33 , 36 , 37 , 40 ], where students reported research skill development and motivation to conduct research in the future [ 38 ]. They were also more likely to publish their completed research papers or present their abstracts at conferences ( n  = 7/12, 58%) [ 21 , 27 , 28 , 32 , 36 , 37 , 40 ].

Multimodal Approach

Studies undertaking a multimodal approach observed outcomes relevant to both didactic teaching and research mentorship. Integrating supervised research projects into curriculum significantly improved medical students’ self-perceived research experiences (level 1) [ 37 , 39 ], and was similarly associated with a large proportion of research publications and presentations ( n  = 12/18, 66%) (level 3). Four studies that incorporated both didactic teaching and a mentored research experience resulted in publication rates of over 50% [ 13 , 32 , 34 , 35 ]. In addition, one study highlighted a level 4 outcome by assessing the post-intervention effects on participants. The study revealed that the longitudinal application of research skills paved the way for future participation in research and attainment of research accolades [ 25 ].

Curricular Incorporation

Nineteen studies (54.3%) offered research programs to students on an elective basis, of which 10 produced level 3 outcomes, where students were successful in presenting their research and listed as co-authors [ 15 , 17 , 22 , 25 , 26 , 29 , 33 , 34 , 40 , 42 ]. Such elective programs were provided on a sign-up basis and took the form of summer programs or additional courses conducted outside of curriculum time. Notably, students have been noted to be engaged in research even after the course of the program [ 25 ].

Sixteen studies (45.7%) conducted research education as a compulsory portion of the medical undergraduate program. Studies devote a portion of the undergraduate curriculum to research education in the form of longitudinal or short-term modules. Similarly, more than half of these studies showcased students publishing articles during medical school. Unique to this group of studies was the reporting of level 2 outcomes, where students exhibited a gain in research knowledge [ 16 , 21 , 28 , 47 , 48 ]. Studies conducting mandatory courses have also been observed to offer research electives to students involving topics of interest. These students likewise proceeded to publish papers under international peer review [ 36 ].

Only 43% ( n  = 15) of all the studies discussed challenges in implementing their respective interventions [ 14 , 16 , 19 , 20 , 26 – 30 , 32 – 34 , 42 , 45 , 48 ]. The most frequently highlighted challenge amongst studies providing basic research theory was a shortage of time ( n  = 2/7, 29%) [ 20 , 48 ], which resulted in insufficient coverage of content.

Participant feedback highlighted a lack of time to complete research projects [ 48 ]. One study noted that multi-year curricula achieved learning objectives by providing sufficient time to facilitate participants’ longitudinal coverage of the community-oriented primary care cycle [ 16 ]. Other challenges surfaced include maintaining the commitment of mentors and finding an appropriate timeslot for the education program to avoid conflicts with other modules of the undergraduate medical program [ 16 , 19 , 20 , 34 ].

Naturally, the multimodal approach shares similar challenges to both pedagogies above. Studies noted a shortage of time to fulfil classroom learning outcomes, as well as to provide a significant window of time for students to undertake research projects under the wing of a mentor [ 26 – 28 , 30 ]. This was exhibited by student requests for more preparation in using statistical analysis software [ 26 ], and community partners’ low ranking of the program timeframe [ 27 ].

This systematic review summarizes the variety of methods that the institutions have utilized to impart research skills to medical students. The analysis highlights two main approaches of teaching these skills: through classroom-based teaching of basic theoretical research skills, and providing students a mentored research experience. Students first developed these skills through didactic teaching methods such as through workshops or seminars, which were then reinforced through the application of these skills under the supervision of a mentor. Our review found that curricula, which utilized both didactic and mentored research components, reliably achieved level 3 outcomes. Programs giving priority to mentoring students in the research process greatly reaped the benefits of mentors. The literature shows that such mentoring resulted in a greater proportion of published papers, compared to exclusively didactic teaching methods. Beyond supervising students, mentors also played an essential role in career counselling and motivating students, and prove to be of significant value in an academic setting [ 2 , 39 , 49 ].

Students’ levels of motivation to learn also bear weight on the outcomes of educational interventions and is of great interest to most educators [ 50 ]. This review found that there were no major differences in the research output of either elective or mandatory research programs. Mandatory research programs were often accompanied by standardized assessments, possibly arising from the institutions’ desires to evaluate the quality of their research education and students’ gain in knowledge [ 28 , 48 ]. It is thus unwise to attribute a recorded gain in knowledge solely to the motivation of students. However, it remains that motivation has a positive impact on the learning of students. Notably, Cluver et al. recorded a continued engagement in research following a research elective program, thereby underscoring the importance of an individual’s interest and motivation towards research [ 25 ].

This study also identified challenges to effectively develop and implement such curricula. Firstly, meaningfully incorporating a comprehensive and systematic research component into the content-heavy medical curricula, especially during the clinical phase of student learning, was difficult. This led institutions to limit the student exposure in research as well as the scope of content covered. Some institutions were able to circumvent this challenge by either integrating research as a longitudinal component of the undergraduate curriculum or dedicating time for students to work on research [ 16 , 21 ]. Studies that spanned at least one academic year achieved a higher number of students with level 3 outcomes. Secondly, mentored programs faced the additional challenge of sourcing for mentors, maintaining their commitment, and equipping them with sufficient knowledge and skills to both educate and provide a holistic learning experience in research. This second challenge was overcome with the inclusion of peer teaching, which eased the need to contend for trained medical professionals [ 22 , 40 ]. It is essential that institutions recognize and strive to overcome these challenges in designing an effective curriculum to equip medical students with research skills.

As part of continuous quality improvement and program reforms, most institutions have developed program evaluation processes. However, these processes heavily relied on participants’ self-reporting Kirkpatrick level 1 outcomes. Few studies focused on higher levels which required independent evaluators or standardized tests to obtain quantitative data. The focus was primarily on capturing short-term outcomes, which failed to highlight the long-term behavioral changes and did not necessarily equate to future application of learnt skills by students [ 11 ]. Program evaluations should strive towards attaining the fourth and final level of the Kirkpatrick model, where students are able to replicate, impart, and apply these competencies in future settings [ 11 ]. Endeavoring to achieve level 4 outcomes would push educational institutions to implement curricula that have an enduring impact on students beyond medical school, allowing them to develop both a capacity and an interest to continue research activities. However, studies face difficulty evaluating such outcomes because it necessitates tedious tracking of graduates’ research performance in their future careers.

An interesting observation was that most studies did not achieve level 2 outcomes as compared to levels 1 and 3. This can be attributed to two possible causes. Firstly, the model does not strictly limit a linear progression from levels 1 to 4. In the case of undergraduate medical research education, there is a prevalent usage of self-assessment tools which resulted in larger proportion of level 1 outcomes. Furthermore, undergoing a mentored research experience often results in a tangible, independently reviewed research product, which qualifies as a level 3 outcome. The second possible reason could be due to the additional required effort of preparing a quiz and conducting a pre- and post-tests, resulting in a lower number of published literatures on level 2 outcomes. This is as opposed to level 3 outcomes which are easily objectively measured by the number of journal publications or conference presentations, and level 1 outcomes through feedback surveys. Nevertheless, there are increasing doubts regarding the individual’s capacity to conduct self-assessments, which gives rise to self-inflated scores and inadequate learning of non-motivated students [ 51 ]. This calls for designing evaluations with more objective data points and long-term structured mentoring, which could bridge these gaps.

In order to achieve long-term and higher levels of outcomes, institutions need to design and cater curricula to students at different stages of research skill acquisition as they face different issues and disparate educational experiences depending on the level of competency they possess [ 52 ]. The Dreyfus model of skill acquisition presents five developmental stages— novice , advanced beginner , competent , proficient , and expert —that describes a shift from tedious analysis in line with abstract and rigid principles to a concrete foundation of experience that enables expeditious intuitive decision-making [ 53 ]. Adopting this model for research education introduces the need to teach these skills in a systematic and longitudinal fashion that is meaningfully integrated to the core medical curriculum. The curriculum can be structured in a way to teach the basic fundamentals of research to newer participants ( novices and advanced beginners ) and then move on to practical skills and real-life practice of paper-writing and statistical analysis for experienced students ( advanced beginners , competent , and proficient students) in later years of learning as well as to inculcate values and behaviors in students who have attained more proficient research abilities ( proficient and expert students) (Fig. ​ (Fig.2 2 ).

Dreyfus model of skill acquisition

The allocation of curriculum time to developing the research skills of students hinges upon the focus and goals of the individual institution. The formation of an intercalated program to nurture clinician-scientists will therefore preferentially expose students to a wide range of research opportunities and research seminars [ 54 ]. However, medical research is but one of the components of the undergraduate medical curriculum. The limitations and challenges discussed earlier hinder undergraduate medical students from potentially advancing to the higher tiers of the Dreyfus model [ 16 , 28 , 30 , 40 ]. It is thus impractical to expect institutions and students to achieve competency within the span of the course. Instead, institutions should opt to develop a curriculum streamlined according to students’ skill levels that will maximize the limited time students have under the institution’s care and jurisdiction and facilitate a more appropriate assignment of students to mentors who possess different resources and research projects at hand.

Most students enter the research fraternity with no prior research experience and start as novices, unfamiliar with research protocol and relevant analytical tools [ 55 ]. Such students require straightforward, rigid rules and guidelines to familiarize themselves with the various steps in conducting research. Offering novice students an opportunity to learn research in a safe environment is essential in lowering the barriers to entry and to demystify the processes for acquiring research skills and critical analytical skills [ 56 , 57 ]. As such, novices benefit greatly from didactic teaching modalities that elucidate theories and methodologies underlying research, focusing on the foundation knowledge needed for research [ 58 ]. After attaining a theoretical understanding of research, novices can progress to an advanced beginner through continuous testing of concepts and developing some functional skills. Advanced beginners better appreciate each step of the research process but require active recollection and effort to complete each task, and face difficulty with practical applications. For these students, curricula should provide students opportunities to join simple research projects under mentors, to allow them to accumulate experience, develop practical skills, and allow them to consolidate their knowledge to progress to the next stage, competency [ 59 ]. Institutions should expose students at this stage to a broader range of research projects in different fields, allowing them to accumulate experience from various medical fields. Competent individuals are able to complete most tasks involved in writing a paper but remain reliant on guidelines, especially in unfamiliar contexts, and thus require the scrutiny and supervision of mentors [ 60 ]. The accumulation of experience from various fields will allow them to develop pattern-recognition, thereby reducing their dependence on rigid rules, augmenting their quality of research. Most undergraduate medical students fall in the above categories, with the achieving of higher tiers of expertise restricted to an exceptional few, or to the domain of postgraduate courses and professional researchers.

The proficient individual undertakes sustained active participation in research to accumulate experience. Students proficient in research have sharpened research skills, a significant understanding of the relevant analytical methods and resources in place. Moreover, they have an awareness of their interests, strengths, and weaknesses—critical for self-regulation—and are thereby able to consistently produce better quality research compared to their peers [ 59 ]. Institutions best serve by connecting students to organizations or experts with additional resources and research opportunities, which students may not be able to procure as individuals. It is also at this stage where students are sufficiently skilled to become peer mentors themselves. This process of peer mentoring further polishes research skills and makes individuals cognizant of knowledge gaps. In addition, students undergoing mentorship programs were more likely to take responsibility of both their own and their peers’ learning, ultimately facilitating tangible results [ 61 , 62 ]. Without mentoring, students in included studies often hit a glass ceiling at level 1 outcomes. This suggests that neither interest nor knowledge alone can propel a student towards desired behavioral changes. Rather, mentoring is the key to inducing a greater form of change amongst research students by allowing to them be engaged and inspire confidence in them [ 13 ]. This will also overcome the challenge highlighted earlier of recruiting faculty mentors and maintaining their commitment. Peer mentors have the relevant advantages of a lower cost, add to a larger pool of potential mentors, lend credibility and effectiveness in role modelling, and help develop a common perspective [ 63 ]. It is therefore of great value to institutions to involve proficient students as peer mentors in longitudinal mentorship programs, with additional guidance from faculty mentors or supervisors to develop intuitive research practices [ 60 ].

With cumulative experience as both mentee and mentor, proficient individuals eventually progress to become experts . Experts are distinguished by behavioral and attitude changes. This is key in a student’s journey towards becoming a clinician-scientist as this is marked by an endeavor to conduct research and contribute to existing literature. Experts possess experience in conducting research and writing research papers and are able to function more intuitively when tackling challenges and solving problems compared to their peers [ 58 ]. Curricula should focus on involving such students as mentors which will facilitate their own continuous education and prevent regression of skills [ 60 ]. This course of ramping up curricula in alignment with the Dreyfus model has been detailed in other studies and similarly underscore the progression from basic knowledge to functional skills and personal growth [ 60 , 64 ]. This ultimately equips students of different stages to meet challenges along their research journey in the limited time undergraduates have under an institution [ 58 ].

Theoretically, the Dreyfus model describes a progressive acquisition of research skills for a novice to become an expert. A student who achieves the level of an expert would undoubtedly possess a remarkable level of intuition and refined skillsets. However, most curricula from the included studies only facilitated students’ growth up to a certain point along the Dreyfus model. While the Dreyfus model serves as a guide to suggest how institutions may best nurture students from a broad spectrum of abilities, the role of undergraduate medical research education is not to simply achieve mastery. Rather, it is to develop the abilities of individuals. Presented with the challenges and limitations discussed earlier, institutions should endeavor to serve as a stepping stone in a student’s journey as a medical practitioner or researcher and to develop an enduring interest and improved capacity for research.

Recommendations

We present the following recommendations for consideration for institutions aiming to design curricula including research exposure.

• Adopt a longitudinal approach—Research modules spanning a longer period allow sufficient time to build a strong research foundation, multiple research opportunities, and greater rates of completion
• Mandate and incorporate research education into the core curriculum—Recognizing research as a core component of education and dedicating time minimizes future scheduling and resource conflicts with other modules of the program.
• Engage and consider student mentors—Mentors are indispensable in research training and should be engaged to ensure sustained, long-term commitment. Utilizing student mentors would further increase both the mentors’ and mentees’ commitment to learn, improve, and polish their acquired skills.

Limitations

This systematic review acknowledges a few limitations. Firstly, our review only considered studies observing undergraduate medical education incorporating research skills and did not consider postgraduate research degree studies such as Masters, MD, or PhD programs, which has greater rigor and a higher level of understanding for research. Next, we were also limited by the inherent quality and scope of the included studies, which lacked data on evaluative models. Currently, the available studies assess effectiveness of medical research educational programs using a myriad of internally designed questionnaires and tests and lack a consistent objective framework to evaluate the effectiveness of their intervention. Furthermore, many studies failed to determine the extent of participants’ prior experience in research and made minimal adjustments to curricula accordingly. As such, it was challenging to observe any enduring impact of the curricula on students.

Research literacy remains important for equipping clinicians with the analytical skills to tackle an ever-evolving medical landscape and maintain an evidence-based approach when treating patients. This systematic review has reiterated the value of incorporating a longitudinal mentorship program in the medical undergraduate curricula and has highlighted the importance of tailoring educational interventions, to allow students with varying experience to develop their skills and initiate the learning process for students without prior experience. There is still room for further investigation of multiple factors such as duration of intervention, student voluntariness, and participants’ prior research experience. Nevertheless, it stands that mentoring is a crucial aspect of curricula that has allowed studies to achieve level 3 Kirkpatrick outcomes and engender enduring changes in students.

(PDF 9 kb)

Acknowledgments

The authors would like to thank Ms. Annelissa Chin from Yong Loo Lin School of Medicine, medical library for assisting us with the search strategy.

Compliance with Ethical Standards

The authors declare that they have no competing interests.

Publisher’s Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

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• Radiology Thesis – More than 400 Research Topics (2022)!

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Introduction

A thesis or dissertation, as some people would like to call it, is an integral part of the Radiology curriculum, be it MD, DNB, or DMRD. We have tried to aggregate radiology thesis topics from various sources for reference.

Not everyone is interested in research, and writing a Radiology thesis can be daunting. But there is no escape from preparing, so it is better that you accept this bitter truth and start working on it instead of cribbing about it (like other things in life. #PhilosophyGyan!)

Start working on your thesis as early as possible and finish your thesis well before your exams, so you do not have that stress at the back of your mind. Also, your thesis may need multiple revisions, so be prepared and allocate time accordingly.

Tips for Choosing Radiology Thesis and Research Topics

Keep it simple silly (kiss).

Retrospective > Prospective

Retrospective studies are better than prospective ones, as you already have the data you need when choosing to do a retrospective study. Prospective studies are better quality, but as a resident, you may not have time (, energy and enthusiasm) to complete these.

Choose a simple topic that answers a single/few questions

Original research is challenging, especially if you do not have prior experience. I would suggest you choose a topic that answers a single or few questions. Most topics that I have listed are along those lines. Alternatively, you can choose a broad topic such as “Role of MRI in evaluation of perianal fistulas.”

You can choose a novel topic if you are genuinely interested in research AND have a good mentor who will guide you. Once you have done that, make sure that you publish your study once you are done with it.

Get it done ASAP.

In most cases, it makes sense to stick to a thesis topic that will not take much time. That does not mean you should ignore your thesis and ‘Ctrl C + Ctrl V’ from a friend from another university. Thesis writing is your first step toward research methodology so do it as sincerely as possible. Do not procrastinate in preparing the thesis. As soon as you have been allotted a guide, start researching topics and writing a review of the literature.

At the same time, do not invest a lot of time in writing/collecting data for your thesis. You should not be busy finishing your thesis a few months before the exam. Some people could not appear for the exam because they could not submit their thesis in time. So DO NOT TAKE thesis lightly.

Do NOT Copy-Paste

Reiterating once again, do not simply choose someone else’s thesis topic. Find out what are kind of cases that your Hospital caters to. It is better to do a good thesis on a common topic than a crappy one on a rare one.

Books to help you write a Radiology Thesis

Event country/university has a different format for thesis; hence these book recommendations may not work for everyone.

• Amazon Kindle Edition
• Gupta, Piyush (Author)
• English (Publication Language)
• 206 Pages - 10/12/2020 (Publication Date) - Jaypee Brothers Medical Publishers (P) Ltd. (Publisher)

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List of Radiology Research /Thesis / Dissertation Topics

• State of the art of MRI in the diagnosis of hepatic focal lesions
• Multimodality imaging evaluation of sacroiliitis in newly diagnosed patients of spondyloarthropathy
• Multidetector computed tomography in oesophageal varices
• Role of positron emission tomography with computed tomography in the diagnosis of cancer Thyroid
• Evaluation of focal breast lesions using ultrasound elastography
• Role of MRI diffusion tensor imaging in the assessment of traumatic spinal cord injuries
• Sonographic imaging in male infertility
• Comparison of color Doppler and digital subtraction angiography in occlusive arterial disease in patients with lower limb ischemia
• The role of CT urography in Haematuria
• Role of functional magnetic resonance imaging in making brain tumor surgery safer
• Prediction of pre-eclampsia and fetal growth restriction by uterine artery Doppler
• Role of grayscale and color Doppler ultrasonography in the evaluation of neonatal cholestasis
• Validity of MRI in the diagnosis of congenital anorectal anomalies
• Role of sonography in assessment of clubfoot
• Role of diffusion MRI in preoperative evaluation of brain neoplasms
• Imaging of upper airways for pre-anaesthetic evaluation purposes and for laryngeal afflictions.
• A study of multivessel (arterial and venous) Doppler velocimetry in intrauterine growth restriction
• Multiparametric 3tesla MRI of suspected prostatic malignancy.
• Role of Sonography in Characterization of Thyroid Nodules for differentiating benign from
• Role of advances magnetic resonance imaging sequences in multiple sclerosis
• Role of multidetector computed tomography in evaluation of jaw lesions
• Role of Ultrasound and MR Imaging in the Evaluation of Musculotendinous Pathologies of Shoulder Joint
• Role of perfusion computed tomography in the evaluation of cerebral blood flow, blood volume and vascular permeability of cerebral neoplasms
• MRI flow quantification in the assessment of the commonest csf flow abnormalities
• Role of diffusion-weighted MRI in evaluation of prostate lesions and its histopathological correlation
• CT enterography in evaluation of small bowel disorders
• Comparison of perfusion magnetic resonance imaging (PMRI), magnetic resonance spectroscopy (MRS) in and positron emission tomography-computed tomography (PET/CT) in post radiotherapy treated gliomas to detect recurrence
• Role of multidetector computed tomography in evaluation of paediatric retroperitoneal masses
• Role of Multidetector computed tomography in neck lesions
• Estimation of standard liver volume in Indian population
• Role of MRI in evaluation of spinal trauma
• Role of modified sonohysterography in female factor infertility: a pilot study.
• The role of pet-CT in the evaluation of hepatic tumors
• Role of 3D magnetic resonance imaging tractography in assessment of white matter tracts compromise in supratentorial tumors
• Role of dual phase multidetector computed tomography in gallbladder lesions
• Role of multidetector computed tomography in assessing anatomical variants of nasal cavity and paranasal sinuses in patients of chronic rhinosinusitis.
• magnetic resonance spectroscopy in multiple sclerosis
• Evaluation of thyroid nodules by ultrasound elastography using acoustic radiation force impulse (ARFI) imaging
• Role of Magnetic Resonance Imaging in Intractable Epilepsy
• Evaluation of suspected and known coronary artery disease by 128 slice multidetector CT.
• Role of regional diffusion tensor imaging in the evaluation of intracranial gliomas and its histopathological correlation
• Role of chest sonography in diagnosing pneumothorax
• Role of CT virtual cystoscopy in diagnosis of urinary bladder neoplasia
• Role of MRI in assessment of valvular heart diseases
• High resolution computed tomography of temporal bone in unsafe chronic suppurative otitis media
• Multidetector CT urography in the evaluation of hematuria
• Contrast-induced nephropathy in diagnostic imaging investigations with intravenous iodinated contrast media
• Comparison of dynamic susceptibility contrast-enhanced perfusion magnetic resonance imaging and single photon emission computed tomography in patients with little’s disease
• Role of Multidetector Computed Tomography in Bowel Lesions.
• Role of diagnostic imaging modalities in evaluation of post liver transplantation recipient complications.
• Role of multislice CT scan and barium swallow in the estimation of oesophageal tumour length
• Malignant Lesions-A Prospective Study.
• Value of ultrasonography in assessment of acute abdominal diseases in pediatric age group
• Role of three dimensional multidetector CT hysterosalpingography in female factor infertility
• Comparative evaluation of multi-detector computed tomography (MDCT) virtual tracheo-bronchoscopy and fiberoptic tracheo-bronchoscopy in airway diseases
• Role of Multidetector CT in the evaluation of small bowel obstruction
• Sonographic evaluation in adhesive capsulitis of shoulder
• Utility of MR Urography Versus Conventional Techniques in Obstructive Uropathy
• MRI of the postoperative knee
• Role of 64 slice-multi detector computed tomography in diagnosis of bowel and mesenteric injury in blunt abdominal trauma.
• Sonoelastography and triphasic computed tomography in the evaluation of focal liver lesions
• Evaluation of Role of Transperineal Ultrasound and Magnetic Resonance Imaging in Urinary Stress incontinence in Women
• Multidetector computed tomographic features of abdominal hernias
• Evaluation of lesions of major salivary glands using ultrasound elastography
• Transvaginal ultrasound and magnetic resonance imaging in female urinary incontinence
• MDCT colonography and double-contrast barium enema in evaluation of colonic lesions
• Role of MRI in diagnosis and staging of urinary bladder carcinoma
• Spectrum of imaging findings in children with febrile neutropenia.
• Spectrum of radiographic appearances in children with chest tuberculosis.
• Role of computerized tomography in evaluation of mediastinal masses in pediatric
• Diagnosing renal artery stenosis: Comparison of multimodality imaging in diabetic patients
• Role of multidetector CT virtual hysteroscopy in the detection of the uterine & tubal causes of female infertility
• Role of multislice computed tomography in evaluation of crohn’s disease
• CT quantification of parenchymal and airway parameters on 64 slice MDCT in patients of chronic obstructive pulmonary disease
• Comparative evaluation of MDCT  and 3t MRI in radiographically detected jaw lesions.
• Evaluation of diagnostic accuracy of ultrasonography, colour Doppler sonography and low dose computed tomography in acute appendicitis
• Ultrasonography , magnetic resonance cholangio-pancreatography (MRCP) in assessment of pediatric biliary lesions
• Multidetector computed tomography in hepatobiliary lesions.
• Evaluation of peripheral nerve lesions with high resolution ultrasonography and colour Doppler
• Multidetector computed tomography in pancreatic lesions
• Multidetector Computed Tomography in Paediatric abdominal masses.
• Evaluation of focal liver lesions by colour Doppler and MDCT perfusion imaging
• Sonographic evaluation of clubfoot correction during Ponseti treatment
• Role of multidetector CT in characterization of renal masses
• Study to assess the role of Doppler ultrasound in evaluation of arteriovenous (av) hemodialysis fistula and the complications of hemodialysis vasular access
• Comparative study of multiphasic contrast-enhanced CT and contrast-enhanced MRI in the evaluation of hepatic mass lesions
• Sonographic spectrum of rheumatoid arthritis
• Diagnosis & staging of liver fibrosis by ultrasound elastography in patients with chronic liver diseases
• Role of multidetector computed tomography in assessment of jaw lesions.
• Role of high-resolution ultrasonography in the differentiation of benign and malignant thyroid lesions
• Radiological evaluation of aortic aneurysms in patients selected for endovascular repair
• Role of conventional MRI, and diffusion tensor imaging tractography in evaluation of congenital brain malformations
• To evaluate the status of coronary arteries in patients with non-valvular atrial fibrillation using 256 multirow detector CT scan
• A comparative study of ultrasonography and CT – arthrography in diagnosis of chronic ligamentous and meniscal injuries of knee
• Multi detector computed tomography evaluation in chronic obstructive pulmonary disease and correlation with severity of disease
• Diffusion weighted and dynamic contrast enhanced magnetic resonance imaging in chemoradiotherapeutic response evaluation in cervical cancer.
• High resolution sonography in the evaluation of non-traumatic painful wrist
• The role of trans-vaginal ultrasound versus magnetic resonance imaging in diagnosis & evaluation of cancer cervix
• Role of multidetector row computed tomography in assessment of maxillofacial trauma
• Imaging of vascular complication after liver transplantation.
• Role of magnetic resonance perfusion weighted imaging & spectroscopy for grading of glioma by correlating perfusion parameter of the lesion with the final histopathological grade
• Magnetic resonance evaluation of abdominal tuberculosis.
• Diagnostic usefulness of low dose spiral HRCT in diffuse lung diseases
• Role of dynamic contrast enhanced and diffusion weighted magnetic resonance imaging in evaluation of endometrial lesions
• Contrast enhanced digital mammography anddigital breast tomosynthesis in early diagnosis of breast lesion
• Evaluation of Portal Hypertension with Colour Doppler flow imaging and magnetic resonance imaging
• Evaluation of musculoskeletal lesions by magnetic resonance imaging
• Role of diffusion magnetic resonance imaging in assessment of neoplastic and inflammatory brain lesions
• Radiological spectrum of chest diseases in HIV infected children High resolution ultrasonography in neck masses in children
• with surgical findings
• Sonographic evaluation of peripheral nerves in type 2 diabetes mellitus.
• Role of perfusion computed tomography in the evaluation of neck masses and correlation
• Role of ultrasonography in the diagnosis of knee joint lesions
• Role of ultrasonography in evaluation of various causes of pelvic pain in first trimester of pregnancy.
• Role of Magnetic Resonance Angiography in the Evaluation of Diseases of Aorta and its Branches
• MDCT fistulography in evaluation of fistula in Ano
• Role of multislice CT in diagnosis of small intestine tumors
• Role of high resolution CT in differentiation between benign and malignant pulmonary nodules in children
• A study of multidetector computed tomography urography in urinary tract abnormalities
• Role of high resolution sonography in assessment of ulnar nerve in patients with leprosy.
• Pre-operative radiological evaluation of locally aggressive and malignant musculoskeletal tumours by computed tomography and magnetic resonance imaging.
• The role of ultrasound & MRI in acute pelvic inflammatory disease
• Ultrasonography compared to computed tomographic arthrography in the evaluation of shoulder pain
• Role of Multidetector Computed Tomography in patients with blunt abdominal trauma.
• The Role of Extended field-of-view Sonography and compound imaging in Evaluation of Breast Lesions
• Evaluation of focal pancreatic lesions by Multidetector CT and perfusion CT
• Evaluation of breast masses on sono-mammography and colour Doppler imaging
• Role of CT virtual laryngoscopy in evaluation of laryngeal masses
• Triple phase multi detector computed tomography in hepatic masses
• Role of transvaginal ultrasound in diagnosis and treatment of female infertility
• Role of ultrasound and color Doppler imaging in assessment of acute abdomen due to female genetal causes
• High resolution ultrasonography and color Doppler ultrasonography in scrotal lesion
• Evaluation of diagnostic accuracy of ultrasonography with colour Doppler vs low dose computed tomography in salivary gland disease
• Role of multidetector CT in diagnosis of salivary gland lesions
• Comparison of diagnostic efficacy of ultrasonography and magnetic resonance cholangiopancreatography in obstructive jaundice: A prospective study
• Evaluation of varicose veins-comparative assessment of low dose CT venogram with sonography: pilot study
• Role of mammotome in breast lesions
• The role of interventional imaging procedures in the treatment of selected gynecological disorders
• Role of transcranial ultrasound in diagnosis of neonatal brain insults
• Role of multidetector CT virtual laryngoscopy in evaluation of laryngeal mass lesions
• Evaluation of adnexal masses on sonomorphology and color Doppler imaginig
• Role of radiological imaging in diagnosis of endometrial carcinoma
• Comprehensive imaging of renal masses by magnetic resonance imaging
• The role of 3D & 4D ultrasonography in abnormalities of fetal abdomen
• Diffusion weighted magnetic resonance imaging in diagnosis and characterization of brain tumors in correlation with conventional MRI
• Role of diffusion weighted MRI imaging in evaluation of cancer prostate
• Role of multidetector CT in diagnosis of urinary bladder cancer
• Role of multidetector computed tomography in the evaluation of paediatric retroperitoneal masses.
• Comparative evaluation of gastric lesions by double contrast barium upper G.I. and multi detector computed tomography
• Evaluation of hepatic fibrosis in chronic liver disease using ultrasound elastography
• Role of MRI in assessment of hydrocephalus in pediatric patients
• The role of sonoelastography in characterization of breast lesions
• The influence of volumetric tumor doubling time on survival of patients with intracranial tumours
• Role of perfusion computed tomography in characterization of colonic lesions
• Role of proton MRI spectroscopy in the evaluation of temporal lobe epilepsy
• Role of Doppler ultrasound and multidetector CT angiography in evaluation of peripheral arterial diseases.
• Role of multidetector computed tomography in paranasal sinus pathologies
• Role of virtual endoscopy using MDCT in detection & evaluation of gastric pathologies
• High resolution 3 Tesla MRI in the evaluation of ankle and hindfoot pain.
• Transperineal ultrasonography in infants with anorectal malformation
• CT portography using MDCT versus color Doppler in detection of varices in cirrhotic patients
• Role of CT urography in the evaluation of a dilated ureter
• Characterization of pulmonary nodules by dynamic contrast-enhanced multidetector CT
• Comprehensive imaging of acute ischemic stroke on multidetector CT
• The role of fetal MRI in the diagnosis of intrauterine neurological congenital anomalies
• Role of Multidetector computed tomography in pediatric chest masses
• Multimodality imaging in the evaluation of palpable & non-palpable breast lesion.
• Sonographic Assessment Of Fetal Nasal Bone Length At 11-28 Gestational Weeks And Its Correlation With Fetal Outcome.
• Role Of Sonoelastography And Contrast-Enhanced Computed Tomography In Evaluation Of Lymph Node Metastasis In Head And Neck Cancers
• Role Of Renal Doppler And Shear Wave Elastography In Diabetic Nephropathy
• Evaluation Of Relationship Between Various Grades Of Fatty Liver And Shear Wave Elastography Values
• Evaluation and characterization of pelvic masses of gynecological origin by USG, color Doppler and MRI in females of reproductive age group
• Radiological evaluation of small bowel diseases using computed tomographic enterography
• Role of coronary CT angiography in patients of coronary artery disease
• Role of multimodality imaging in the evaluation of pediatric neck masses
• Role of CT in the evaluation of craniocerebral trauma
• Role of magnetic resonance imaging (MRI) in the evaluation of spinal dysraphism
• Comparative evaluation of triple phase CT and dynamic contrast-enhanced MRI in patients with liver cirrhosis
• Evaluation of the relationship between carotid intima-media thickness and coronary artery disease in patients evaluated by coronary angiography for suspected CAD
• Assessment of hepatic fat content in fatty liver disease by unenhanced computed tomography
• Correlation of vertebral marrow fat on spectroscopy and diffusion-weighted MRI imaging with bone mineral density in postmenopausal women.
• Comparative evaluation of CT coronary angiography with conventional catheter coronary angiography
• Ultrasound evaluation of kidney length & descending colon diameter in normal and intrauterine growth-restricted fetuses
• A prospective study of hepatic vein waveform and splenoportal index in liver cirrhosis: correlation with child Pugh’s classification and presence of esophageal varices.
• CT angiography to evaluate coronary artery by-pass graft patency in symptomatic patient’s functional assessment of myocardium by cardiac MRI in patients with myocardial infarction
• MRI evaluation of HIV positive patients with central nervous system manifestations
• MDCT evaluation of mediastinal and hilar masses
• Evaluation of rotator cuff & labro-ligamentous complex lesions by MRI & MRI arthrography of shoulder joint
• Role of imaging in the evaluation of soft tissue vascular malformation
• Role of MRI and ultrasonography in the evaluation of multifidus muscle pathology in chronic low back pain patients
• Role of ultrasound elastography in the differential diagnosis of breast lesions
• Role of magnetic resonance cholangiopancreatography in evaluating dilated common bile duct in patients with symptomatic gallstone disease.
• Comparative study of CT urography & hybrid CT urography in patients with haematuria.
• Role of MRI in the evaluation of anorectal malformations
• Comparison of ultrasound-Doppler and magnetic resonance imaging findings in rheumatoid arthritis of hand and wrist
• Role of Doppler sonography in the evaluation of renal artery stenosis in hypertensive patients undergoing coronary angiography for coronary artery disease.
• Comparison of radiography, computed tomography and magnetic resonance imaging in the detection of sacroiliitis in ankylosing spondylitis.
• Mr evaluation of painful hip
• Role of MRI imaging in pretherapeutic assessment of oral and oropharyngeal malignancy
• Evaluation of diffuse lung diseases by high resolution computed tomography of the chest
• Mr evaluation of brain parenchyma in patients with craniosynostosis.
• Diagnostic and prognostic value of cardiovascular magnetic resonance imaging in dilated cardiomyopathy
• Role of multiparametric magnetic resonance imaging in the detection of early carcinoma prostate
• Role of magnetic resonance imaging in white matter diseases
• Role of sonoelastography in assessing the response to neoadjuvant chemotherapy in patients with locally advanced breast cancer.
• Role of ultrasonography in the evaluation of carotid and femoral intima-media thickness in predialysis patients with chronic kidney disease
• Role of H1 MRI spectroscopy in focal bone lesions of peripheral skeleton choline detection by MRI spectroscopy in breast cancer and its correlation with biomarkers and histological grade.
• Ultrasound and MRI evaluation of axillary lymph node status in breast cancer.
• Role of sonography and magnetic resonance imaging in evaluating chronic lateral epicondylitis.
• Comparative of sonography including Doppler and sonoelastography in cervical lymphadenopathy.
• Evaluation of Umbilical Coiling Index as Predictor of Pregnancy Outcome.
• Computerized Tomographic Evaluation of Azygoesophageal Recess in Adults.
• Lumbar Facet Arthropathy in Low Backache.
• “Urethral Injuries After Pelvic Trauma: Evaluation with Uretrography
• Role Of Ct In Diagnosis Of Inflammatory Renal Diseases
• Role Of Ct Virtual Laryngoscopy In Evaluation Of Laryngeal Masses
• “Ct Portography Using Mdct Versus Color Doppler In Detection Of Varices In
• Cirrhotic Patients”
• Role Of Multidetector Ct In Characterization Of Renal Masses
• Role Of Ct Virtual Cystoscopy In Diagnosis Of Urinary Bladder Neoplasia
• Role Of Multislice Ct In Diagnosis Of Small Intestine Tumors
• “Mri Flow Quantification In The Assessment Of The Commonest CSF Flow Abnormalities”
• “The Role Of Fetal Mri In Diagnosis Of Intrauterine Neurological CongenitalAnomalies”
• Role Of Transcranial Ultrasound In Diagnosis Of Neonatal Brain Insults
• “The Role Of Interventional Imaging Procedures In The Treatment Of Selected Gynecological Disorders”
• Role Of Radiological Imaging In Diagnosis Of Endometrial Carcinoma
• “Role Of High-Resolution Ct In Differentiation Between Benign And Malignant Pulmonary Nodules In Children”
• Role Of Ultrasonography In The Diagnosis Of Knee Joint Lesions
• “Role Of Diagnostic Imaging Modalities In Evaluation Of Post Liver Transplantation Recipient Complications”
• “Diffusion-Weighted Magnetic Resonance Imaging In Diagnosis And
• Characterization Of Brain Tumors In Correlation With Conventional Mri”
• The Role Of PET-CT In The Evaluation Of Hepatic Tumors
• “Role Of Computerized Tomography In Evaluation Of Mediastinal Masses In Pediatric patients”
• “Trans Vaginal Ultrasound And Magnetic Resonance Imaging In Female Urinary Incontinence”
• Role Of Multidetector Ct In Diagnosis Of Urinary Bladder Cancer
• “Role Of Transvaginal Ultrasound In Diagnosis And Treatment Of Female Infertility”
• Role Of Diffusion-Weighted Mri Imaging In Evaluation Of Cancer Prostate
• “Role Of Positron Emission Tomography With Computed Tomography In Diagnosis Of Cancer Thyroid”
• The Role Of CT Urography In Case Of Haematuria
• “Value Of Ultrasonography In Assessment Of Acute Abdominal Diseases In Pediatric Age Group”
• “Role Of Functional Magnetic Resonance Imaging In Making Brain Tumor Surgery Safer”
• The Role Of Sonoelastography In Characterization Of Breast Lesions
• “Ultrasonography, Magnetic Resonance Cholangiopancreatography (MRCP) In Assessment Of Pediatric Biliary Lesions”
• “Role Of Ultrasound And Color Doppler Imaging In Assessment Of Acute Abdomen Due To Female Genital Causes”
• “Role Of Multidetector Ct Virtual Laryngoscopy In Evaluation Of Laryngeal Mass Lesions”
• MRI Of The Postoperative Knee
• Role Of Mri In Assessment Of Valvular Heart Diseases
• The Role Of 3D & 4D Ultrasonography In Abnormalities Of Fetal Abdomen
• State Of The Art Of Mri In Diagnosis Of Hepatic Focal Lesions
• Role Of Multidetector Ct In Diagnosis Of Salivary Gland Lesions
• “Role Of Virtual Endoscopy Using Mdct In Detection & Evaluation Of Gastric Pathologies”
• The Role Of Ultrasound & Mri In Acute Pelvic Inflammatory Disease
• “Diagnosis & Staging Of Liver Fibrosis By Ultraso Und Elastography In
• Patients With Chronic Liver Diseases”
• Role Of Mri In Evaluation Of Spinal Trauma
• Validity Of Mri In Diagnosis Of Congenital Anorectal Anomalies
• Imaging Of Vascular Complication After Liver Transplantation
• “Contrast-Enhanced Digital Mammography And Digital Breast Tomosynthesis In Early Diagnosis Of Breast Lesion”
• Role Of Mammotome In Breast Lesions
• “Role Of MRI Diffusion Tensor Imaging (DTI) In Assessment Of Traumatic Spinal Cord Injuries”
• “Prediction Of Pre-eclampsia And Fetal Growth Restriction By Uterine Artery Doppler”
• “Role Of Multidetector Row Computed Tomography In Assessment Of Maxillofacial Trauma”
• “Role Of Diffusion Magnetic Resonance Imaging In Assessment Of Neoplastic And Inflammatory Brain Lesions”
• Role Of Diffusion Mri In Preoperative Evaluation Of Brain Neoplasms
• “Role Of Multidetector Ct Virtual Hysteroscopy In The Detection Of The
• Uterine & Tubal Causes Of Female Infertility”
• Role Of Advances Magnetic Resonance Imaging Sequences In Multiple Sclerosis Magnetic Resonance Spectroscopy In Multiple Sclerosis
• “Role Of Conventional Mri, And Diffusion Tensor Imaging Tractography In Evaluation Of Congenital Brain Malformations”
• Role Of MRI In Evaluation Of Spinal Trauma
• Diagnostic Role Of Diffusion-weighted MR Imaging In Neck Masses
• “The Role Of Transvaginal Ultrasound Versus Magnetic Resonance Imaging In Diagnosis & Evaluation Of Cancer Cervix”
• “Role Of 3d Magnetic Resonance Imaging Tractography In Assessment Of White Matter Tracts Compromise In Supra Tentorial Tumors”
• Role Of Proton MR Spectroscopy In The Evaluation Of Temporal Lobe Epilepsy
• Role Of Multislice Computed Tomography In Evaluation Of Crohn’s Disease
• Role Of MRI In Assessment Of Hydrocephalus In Pediatric Patients
• The Role Of MRI In Diagnosis And Staging Of Urinary Bladder Carcinoma
• USG and MRI correlation of congenital CNS anomalies
• HRCT in interstitial lung disease
• X-Ray, CT and MRI correlation of bone tumors
• “Study on the diagnostic and prognostic utility of X-Rays for cases of pulmonary tuberculosis under RNTCP”
• “Role of magnetic resonance imaging in the characterization of female adnexal  pathology”
• “CT angiography of carotid atherosclerosis and NECT brain in cerebral ischemia, a correlative analysis”
• Role of CT scan in the evaluation of paranasal sinus pathology
• USG and MRI correlation on shoulder joint pathology
• “Radiological evaluation of a patient presenting with extrapulmonary tuberculosis”
• CT and MRI correlation in focal liver lesions”
• Comparison of MDCT virtual cystoscopy with conventional cystoscopy in bladder tumors”
• “Bleeding vessels in life-threatening hemoptysis: Comparison of 64 detector row CT angiography with conventional angiography prior to endovascular management”
• “Role of transarterial chemoembolization in unresectable hepatocellular carcinoma”
• “Comparison of color flow duplex study with digital subtraction angiography in the evaluation of peripheral vascular disease”
• “A Study to assess the efficacy of magnetization transfer ratio in differentiating tuberculoma from neurocysticercosis”
• “MR evaluation of uterine mass lesions in correlation with transabdominal, transvaginal ultrasound using HPE as a gold standard”
• “The Role of power Doppler imaging with trans rectal ultrasonogram guided prostate biopsy in the detection of prostate cancer”
• “Lower limb arteries assessed with doppler angiography – A prospective comparative study with multidetector CT angiography”
• “Comparison of sildenafil with papaverine in penile doppler by assessing hemodynamic changes”
• “Evaluation of efficacy of sonosalphingogram for assessing tubal patency in infertile patients with hysterosalpingogram as the gold standard”
• Role of CT enteroclysis in the evaluation of small bowel diseases
• “MRI colonography versus conventional colonoscopy in the detection of colonic polyposis”
• “Magnetic Resonance Imaging of anteroposterior diameter of the midbrain – differentiation of progressive supranuclear palsy from Parkinson disease”
• “MRI Evaluation of anterior cruciate ligament tears with arthroscopic correlation”
• “The Clinicoradiological profile of cerebral venous sinus thrombosis with prognostic evaluation using MR sequences”
• “Role of MRI in the evaluation of pelvic floor integrity in stress incontinent patients” “Doppler ultrasound evaluation of hepatic venous waveform in portal hypertension before and after propranolol”
• “Role of transrectal sonography with colour doppler and MRI in evaluation of prostatic lesions with TRUS guided biopsy correlation”
• “Ultrasonographic evaluation of painful shoulders and correlation of rotator cuff pathologies and clinical examination”
• “Colour Doppler Evaluation of Common Adult Hepatic tumors More Than 2 Cm  with HPE and CECT Correlation”
• “Clinical Relevance of MR Urethrography in Obliterative Posterior Urethral Stricture”
• “Prediction of Adverse Perinatal Outcome in Growth Restricted Fetuses with Antenatal Doppler Study”
• Radiological evaluation of spinal dysraphism using CT and MRI
• “Evaluation of temporal bone in cholesteatoma patients by high resolution computed tomography”
• “Radiological evaluation of primary brain tumours using computed tomography and magnetic resonance imaging”
• “Three dimensional colour doppler sonographic assessment of changes in  volume and vascularity of fibroids – before and after uterine artery embolization”
• “In phase opposed phase imaging of bone marrow differentiating neoplastic lesions”
• “Role of dynamic MRI in replacing the isotope renogram in the functional evaluation of PUJ obstruction”
• Characterization of adrenal masses with contrast-enhanced CT – washout study
• A study on accuracy of magnetic resonance cholangiopancreatography
• “Evaluation of median nerve in carpal tunnel syndrome by high-frequency ultrasound & color doppler in comparison with nerve conduction studies”
• “Correlation of Agatston score in patients with obstructive and nonobstructive coronary artery disease following STEMI”
• “Doppler ultrasound assessment of tumor vascularity in locally advanced breast cancer at diagnosis and following primary systemic chemotherapy.”
• “Validation of two-dimensional perineal ultrasound and dynamic magnetic resonance imaging in pelvic floor dysfunction.”
• “Role of MR urethrography compared to conventional urethrography in the surgical management of obliterative urethral stricture.”

Search Diagnostic Imaging Research Topics

You can also search research-related resources on our custom search engine .

Free Resources for Preparing Radiology Thesis

• Radiology thesis topics- Benha University – Free to download thesis
• Radiology thesis topics – Faculty of Medical Science Delhi
• Radiology thesis topics – IPGMER
• Fetal Radiology thesis Protocols
• Radiology thesis and dissertation topics
• Radiographics

Proofreading Your Thesis:

Make sure you use Grammarly to correct your spelling ,  grammar , and plagiarism for your thesis. Grammarly has affordable paid subscriptions, windows/macOS apps, and FREE browser extensions. It is an excellent tool to avoid inadvertent spelling mistakes in your research projects. It has an extensive built-in vocabulary, but you should make an account and add your own medical glossary to it.

Guidelines for Writing a Radiology Thesis:

These are general guidelines and not about radiology specifically. You can share these with colleagues from other departments as well. Special thanks to Dr. Sanjay Yadav sir for these. This section is best seen on a desktop. Here are a couple of handy presentations to start writing a thesis:

Read the general guidelines for writing a thesis (the page will take some time to load- more than 70 pages!

A format for thesis protocol with a sample patient information sheet, sample patient consent form, sample application letter for thesis, and sample certificate.

Resources and References:

• Guidelines for thesis writing.
• Format for thesis protocol
• Thesis protocol writing guidelines DNB
• Informed consent form for Research studies from AIIMS 
• Radiology Informed consent forms in local Indian languages.
• Sample Informed Consent form for Research in Hindi
• Guide to write a thesis by Dr. P R Sharma
• Guidelines for thesis writing by Dr. Pulin Gupta.
• Preparing MD/DNB thesis by A Indrayan
• Another good thesis reference protocol

Hopefully, this post will make the tedious task of writing a Radiology thesis a little bit easier for you. Best of luck with writing your thesis and your residency too!

More guides for residents :

• Guide for the MD/DMRD/DNB radiology exam!
• Guide for First-Year Radiology Residents
• FRCR Exam: THE Most Comprehensive Guide (2022)!
• Radiology Practical Exams Questions compilation for MD/DNB/DMRD !

Radiology Exam Resources (Oral Recalls, Instruments, etc )!

• Tips and Tricks for DNB/MD Radiology Practical Exam
• FRCR 2B exam- Tips and Tricks !
• FRCR exam preparation – An alternative take!
• Why did I take up Radiology?
• Radiology Conferences – A comprehensive guide!
• ECR (European Congress Of Radiology)
• European Diploma in Radiology (EDiR) – The Complete Guide!
• Radiology NEET PG guide – How to select THE best college for post-graduation in Radiology (includes personal insights)!
• Interventional Radiology – All Your Questions Answered!

What It Means To Be A Radiologist: A Guide For Medical Students!

• Radiology Mentors for Medical Students (Post NEET-PG)
• MD vs DNB Radiology: Which Path is Right for Your Career?
• DNB Radiology OSCE – Tips and Tricks

More radiology resources here: Radiology resources This page will be updated regularly. Kindly leave your feedback in the comments or send us a message here . Also, you can comment below regarding your department’s thesis topics.

Note: All topics have been compiled from available online resources. If anyone has an issue with any radiology thesis topics displayed here, you can message us here , and we can delete them. These are only sample guidelines. Thesis guidelines differ from institution to institution.

Image source: Thesis complete! (2018). Flickr. Retrieved 12 August 2018, from https://www.flickr.com/photos/cowlet/354911838 by Victoria Catterson

About The Author

Dr. amar udare, md, related posts ↓.

7 thoughts on “Radiology Thesis – More than 400 Research Topics (2022)!”

Amazing & The most helpful site for Radiology residents…

Thank you for your kind comments 🙂

Dr. I saw your Tips is very amazing and referable. But Dr. Can you help me with the thesis of Evaluation of Diagnostic accuracy of X-ray radiograph in knee joint lesion.

Wow! These are excellent stuff. You are indeed a teacher. God bless

Glad you liked these!

happy to see this

Glad I could help :).

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55 research questions about mental health

Last updated

11 March 2024

Reviewed by

Brittany Ferri, PhD, OTR/L

Research in the mental health space helps fill knowledge gaps and create a fuller picture for patients, healthcare professionals, and policymakers. Over time, these efforts result in better quality care and more accessible treatment options for those who need them.

Use this list of mental health research questions to kickstart your next project or assignment and give yourself the best chance of producing successful and fulfilling research.

• Why does mental health research matter?

Mental health research is an essential area of study. It includes any research that focuses on topics related to people’s mental and emotional well-being.

As a complex health topic that, despite the prevalence of mental health conditions, still has an unending number of unanswered questions, the need for thorough research into causes, triggers, and treatment options is clear.

Research into this heavily stigmatized and often misunderstood topic is needed to find better ways to support people struggling with mental health conditions. Understanding what causes them is another crucial area of study, as it enables individuals, companies, and policymakers to make well-informed choices that can help prevent illnesses like anxiety and depression.

• How to choose a strong mental health research topic

As one of the most important parts of beginning a new research project, picking a topic that is intriguing, unique, and in demand is a great way to get the best results from your efforts.

Mental health is a blanket term with many niches and specific areas to explore. But, no matter which direction you choose, follow the tips below to ensure you pick the right topic.

Prioritize your interests and skills

While a big part of research is exploring a new and exciting topic, this exploration is best done within a topic or niche in which you are interested and experienced.

Research is tough, even at the best of times. To combat fatigue and increase your chances of pushing through to the finish line, we recommend choosing a topic that aligns with your personal interests, training, or skill set.

Consider emerging trends

Topical and current research questions are hot commodities because they offer solutions and insights into culturally and socially relevant problems.

Depending on the scope and level of freedom you have with your upcoming research project, choosing a topic that’s trending in your area of study is one way to get support and funding (if you need it).

Not every study can be based on a cutting-edge topic, but this can be a great way to explore a new space and create baseline research data for future studies.

Assess your resources and timeline

Before choosing a super ambitious and exciting research topic, consider your project restrictions.

You’ll need to think about things like your research timeline, access to resources and funding, and expected project scope when deciding how broad your research topic will be. In most cases, it’s better to start small and focus on a specific area of study.

Broad research projects are expensive and labor and resource-intensive. They can take years or even decades to complete. Before biting off more than you can chew, consider your scope and find a research question that fits within it.

Read up on the latest research

Finally, once you have narrowed in on a specific topic, you need to read up on the latest studies and published research. A thorough research assessment is a great way to gain some background context on your chosen topic and stops you from repeating a study design. Using the existing work as your guide, you can explore more specific and niche questions to provide highly beneficial answers and insights.

• Trending research questions for post-secondary students

As a post-secondary student, finding interesting research questions that fit within the scope of your classes or resources can be challenging. But, with a little bit of effort and pre-planning, you can find unique mental health research topics that will meet your class or project requirements.

Examples of research topics for post-secondary students include the following:

How does school-related stress impact a person’s mental health?

To what extent does burnout impact mental health in medical students?

How does chronic school stress impact a student’s physical health?

How does exam season affect the severity of mental health symptoms?

Is mental health counseling effective for students in an acute mental crisis?

• Research questions about anxiety and depression

Anxiety and depression are two of the most commonly spoken about mental health conditions. You might assume that research about these conditions has already been exhausted or that it’s no longer in demand. That’s not the case at all.

According to a 2022 survey by Centers for Disease Control and Prevention (CDC), 12.5% of American adults struggle with regular feelings of worry, nervousness, and anxiety, and 5% struggle with regular feelings of depression. These percentages amount to millions of lives affected, meaning new research into these conditions is essential.

If either of these topics interests you, here are a few trending research questions you could consider:

Does gender play a role in the early diagnosis of anxiety?

How does untreated anxiety impact quality of life?

What are the most common symptoms of anxiety in working professionals aged 20–29?

To what extent do treatment delays impact quality of life in patients with undiagnosed anxiety?

To what extent does stigma affect the quality of care received by people with anxiety?

Here are some examples of research questions about depression:

Does diet play a role in the severity of depression symptoms?

Can people have a genetic predisposition to developing depression?

How common is depression in work-from-home employees?

Does mood journaling help manage depression symptoms?

What role does exercise play in the management of depression symptoms?

• Research questions about personality disorders

Personality disorders are complex mental health conditions tied to a person’s behaviors, sense of self, and how they interact with the world around them. Without a diagnosis and treatment, people with personality disorders are more likely to develop negative coping strategies during periods of stress and adversity, which can impact their quality of life and relationships.

There’s no shortage of specific research questions in this category. Here are some examples of research questions about personality disorders that you could explore:

What environments are more likely to trigger the development of a personality disorder?

What barriers impact access to care for people with personality disorders?

To what extent does undiagnosed borderline personality disorder impact a person’s ability to build relationships?

How does group therapy impact symptom severity in people with schizotypal personality disorder?

What is the treatment compliance rate of people with paranoid personality disorder?

• Research questions about substance use disorders

“Substance use disorders” is a blanket term for treatable behaviors and patterns within a person’s brain that lead them to become dependent on illicit drugs, alcohol, or prescription medications. It’s one of the most stigmatized mental health categories.

The severity of a person’s symptoms and how they impact their ability to participate in their regular daily life can vary significantly from person to person. But, even in less severe cases, people with a substance use disorder display some level of loss of control due to their need to use the substance they are dependent on.

This is an ever-evolving topic where research is in hot demand. Here are some example research questions:

To what extent do meditation practices help with craving management?

How effective are detox centers in treating acute substance use disorder?

Are there genetic factors that increase a person’s chances of developing a substance use disorder?

How prevalent are substance use disorders in immigrant populations?

To what extent do prescription medications play a role in developing substance use disorders?

• Research questions about mental health treatments

Treatments for mental health, pharmaceutical therapies in particular, are a common topic for research and exploration in this space.

Besides the clinical trials required for a drug to receive FDA approval, studies into the efficacy, risks, and patient experiences are essential to better understand mental health therapies.

These types of studies can easily become large in scope, but it’s possible to conduct small cohort research on mental health therapies that can provide helpful insights into the actual experiences of the people receiving these treatments.

Here are some questions you might consider:

What are the long-term effects of electroconvulsive therapy (ECT) for patients with severe depression?

How common is insomnia as a side effect of oral mental health medications?

What are the most common causes of non-compliance for mental health treatments?

How long does it take for patients to report noticeable changes in symptom severity after starting injectable mental health medications?

What issues are most common when weaning a patient off of an anxiety medication?

• Controversial mental health research questions

If you’re interested in exploring more cutting-edge research topics, you might consider one that’s “controversial.”

Depending on your own personal values, you might not think many of these topics are controversial. In the context of the research environment, this depends on the perspectives of your project lead and the desires of your sponsors. These topics may not align with the preferred subject matter.

That being said, that doesn’t make them any less worth exploring. In many cases, it makes them more worthwhile, as they encourage people to ask questions and think critically.

Here are just a few examples of “controversial” mental health research questions:

To what extent do financial crises impact mental health in young adults?

How have climate concerns impacted anxiety levels in young adults?

To what extent do psychotropic drugs help patients struggling with anxiety and depression?

To what extent does political reform impact the mental health of LGBTQ+ people?

What mental health supports should be available for the families of people who opt for medically assisted dying?

• Research questions about socioeconomic factors & mental health

Socioeconomic factors—like where a person grew up, their annual income, the communities they are exposed to, and the amount, type, and quality of mental health resources they have access to—significantly impact overall health.

This is a complex and multifaceted issue. Choosing a research question that addresses these topics can help researchers, experts, and policymakers provide more equitable and accessible care over time.

Examples of questions that tackle socioeconomic factors and mental health include the following:

How does sliding scale pricing for therapy increase retention rates?

What is the average cost to access acute mental health crisis care in [a specific region]?

To what extent does a person’s environment impact their risk of developing a mental health condition?

How does mental health stigma impact early detection of mental health conditions?

To what extent does discrimination affect the mental health of LGBTQ+ people?

• Research questions about the benefits of therapy

Therapy, whether that’s in groups or one-to-one sessions, is one of the most commonly utilized resources for managing mental health conditions. It can help support long-term healing and the development of coping mechanisms.

Yet, despite its popularity, more research is needed to properly understand its benefits and limitations.

Here are some therapy-based questions you could consider to inspire your own research:

In what instances does group therapy benefit people more than solo sessions?

How effective is cognitive behavioral therapy for patients with severe anxiety?

After how many therapy sessions do people report feeling a better sense of self?

Does including meditation reminders during therapy improve patient outcomes?

To what extent has virtual therapy improved access to mental health resources in rural areas?

• Research questions about mental health trends in teens

Adolescents are a particularly interesting group for mental health research due to the prevalence of early-onset mental health symptoms in this age group.

As a time of self-discovery and change, puberty brings plenty of stress, anxiety, and hardships, all of which can contribute to worsening mental health symptoms.

If you’re looking to learn more about how to support this age group with mental health, here are some examples of questions you could explore:

Does parenting style impact anxiety rates in teens?

How early should teenagers receive mental health treatment?

To what extent does cyberbullying impact adolescent mental health?

What are the most common harmful coping mechanisms explored by teens?

How have smartphones affected teenagers’ self-worth and sense of self?

• Research questions about social media and mental health

Social media platforms like TikTok, Instagram, YouTube, Facebook, and X (formerly Twitter) have significantly impacted day-to-day communication. However, despite their numerous benefits and uses, they have also become a significant source of stress, anxiety, and self-worth issues for those who use them.

These platforms have been around for a while now, but research on their impact is still in its infancy. Are you interested in building knowledge about this ever-changing topic? Here are some examples of social media research questions you could consider:

To what extent does TikTok’s mental health content impact people’s perception of their health?

How much non-professional mental health content is created on social media platforms?

How has social media content increased the likelihood of a teen self-identifying themselves with ADHD or autism?

To what extent do social media photoshopped images impact body image and self-worth?

Has social media access increased feelings of anxiety and dread in young adults?

• Mental health research is incredibly important

As you have seen, there are so many unique mental health research questions worth exploring. Which options are piquing your interest?

Whether you are a university student considering your next paper topic or a professional looking to explore a new area of study, mental health is an exciting and ever-changing area of research to get involved with.

Your research will be valuable, no matter how big or small. As a niche area of healthcare still shrouded in stigma, any insights you gain into new ways to support, treat, or identify mental health triggers and trends are a net positive for millions of people worldwide.

Get started today

Go from raw data to valuable insights with a flexible research platform

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215 ideal medical research topics to write on.

September 15, 2021

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Medicine, surgery, nursing, and all health-related fields can seem tough. However, with the right kind of assistance, you will grow well in your career. Here are some of the best medical research topics. They are diverse, dynamic, and systematic.

Medical Research Papers Topics for You

When you go to medical school, you are never sure of what to expect. However, as you get used to the hospital environment and equipment, you learn how to go about it.

• The benefits and dangers of vaccination.
• What is the impact of vaccination on boosting the human immune system?
• The rarest genetic diseases found in children.
• The various humanitarian medical missions in the world.
• The causes of various virus infections.
• The major causes of sleep disorders.
• The difference between terminal and professional diseases.
• The best way to carry out the palliative treatment.
• Does aging cause any changes in mental health?
• The impact of the increased life expectancy on the healthcare system.
• The major moral responsibilities regarding cloning.
• The best ways to implement food standards.
• The debate on Marijuana legalization for medical purposes.
• The major causes of gluten allergy.
• The impact of the safe medical approaches to abortion.

Interesting Medical Anthropology Research Topics

Anthropology is mainly based on people, excavation, origin, history, and socialization of people. It is a broad field! Hence, medical anthropology topics can help you broadly understand people.

• The various nursing ethics issues.
• The common symptoms of celiac disease.
• Evaluate the forensic psychiatry field.
• The theoretical basis of transcultural nursing.
• Euthanasia and its medical ethics.
• The impact of euthanasia when reducing the pain of the patient’s family.
• Evaluate women’s sexuality and their body.
• The health and illnesses in the world’s culture.
• The anthropology of reproduction in humans.
• The anthropology of environmental health.
• The effects of adult-onset diabetes on death rates.
• Analyze the health and nutritional status of prehistoric people.
• The influence of homelessness on the growth of young children.
• The impact of third world poverty on the health of the respective society.
• The relation between environmental health and political ecology.

Controversial Medical Topics for a Research Paper

Some topics can be controversial when they are aligned to a certain phenomenon. Some things may seem ethical in the health care setting, but not in society.

• Do you think assisted suicide for terminal patients is ethical?
• The ethical concerns of testing vaccines on animals.
• The benefits and dangers of a vegan diet.
• The influence of environmental changes on human health.
• The diseases caused by lack of physical exercise
• How does urban pollution affect the getting of respiratory diseases?
• The methods to use to control tobacco and alcohol use.
• The effectiveness of the oral health assessment.
• Diabetes is a public danger to society.
• The various communication disorders.
• The effect of household air pollution on the growth of children.
• The impact of coronavirus spread globally.
• The latest developments in the medical instruments.
• The comparison between treating women versus non-pregnant women.
• The latest developments on AIDS and HIV.

Unique Medical Research Paper Topics

Are you looking for the most unique medical research paper topics? Why not start with any of these! They are easy, diverse, and dynamic.

• The major causes of an increase in cancer cases.
• The impact of terrorism on the mental health of individuals.
• Evaluate the various successful treatments for mental diseases.
• Elaborate on genetic engineering.
• Evaluate how autism is a disease.
• The impact of smoking on organs.
• The causes and effects of heart attacks in humans.
• The inequalities faced when getting health care services.
• The advantages and disadvantages of electronic health records systems.
• The impact of asylums on treating mental issues.
• The major concerns are based on health care for prison inmates.
• The major types of equipment used in improving AIDS treatment.
• The recent developments in the treatment of breast cancer.
• The importance of banning tobacco advertisements to reduce its use.
• The various government solutions to the anti-vaccine movement.

Medical Research Topics for College Students

When in college or university, you can easily get confused when searching for an ideal research project topic. Here are some of the most ideal medical research topics for college students.

• The causes of anxiety disorders on individuals.
• Comparison between bulimia and anorexia.
• How does childhood trauma affect one when one becomes an adult.
• The influence on the mental health public policies.
• The effect of postpartum depression and post-traumatic stress disorder.
• Comparison between dementia and schizophrenia.
• How does chemotherapy affect the body?
• How do the thyroid glands function in the body?
• The development of the human muscular system.
• Evaluate the human endocrine system.
• The effects of liver and heart diseases on the body.
• Elaborate on the various genetic diseases in humans.
• The importance of the lymphatic system.
• The biological effects caused by aging.
• The effect of air pollution on health.

Interesting Medical Topics for Research Papers

You can take a considerable amount of time while doing research papers. If you feel, you don’t have enough time on your plate, our experts can help ease the burden.

• The paths of treatment of Alzheimer’s disease.
• Ebola vaccine and drug development.
• Elaborate on regenerative medicine.
• Biomedical diagnostics and technology.
• The ethical issues concerning organ donation.
• Evaluate the complementary medicine used in health care centers.
• The ethical issues about artificial insemination and surrogacy.
• The effects of contraception on female bodies.
• The environmental bioethics in the society.
• The influence of in-vitro fertilization on increase in population.
• The medical research behind the cloning of animals.
• Elaborate on eugenics.
• The benefits of early cancer detection.
• The major pathogen-related cancers in the world.
• How is artificial intelligence being used to predict cancer?

Most Interesting Medical Research Topics

If you have a passion for treating people, choosing a medical-related field can suit you best. The medical fields require someone passionate about saving lives. These interesting medical research topics will help you start.

• How do the immune system cells fight cancer?
• Is metastasis affected by drug resistance?
• The ethical issues regarding human subject research.
• How do age and obesity influence cancer occurrence in humans?
• Elaborate on how tumors occur and viable treatment.
• The most common pathogen-related cancers.
• Data collection and management in the medical field.
• The impact of using vulnerable populations in clinical research.
• The major clinical practices for health professionals.
• The effectiveness of academic clinical trials versus the clinical trial units.
• The source of financial support for clinical trials.
• The best care and nutrition for critically ill adults.
• The rhythm analysis for cardiac arrest.
• The best way to perform artificial airways functioning.
• The effect of chronic obstructive pulmonary disease.

Medical Ethics Research Paper Topics

When interacting with individuals, it is important to be ethical. In the medical field, some issues may arise when a patient has two options of death or fight for their life. Some people argue that the patient should die rather than feel extreme pain. What’s your take?

• The care ethics for the mentally handicapped.
• The most ethical nursing theories.
• The ethical issues that come from practicing medicine overseas.
• The measurement of ethics in the medical field.
• The importance of medical ethics.
• When it is medically ethical to end a life of a patient.
• The ethics behind the preventive medicines used in health care centers.
• The relation between cultural bias and medical ethics.
• Is it ethical for robots to replace doctors and nurses in the hospital?
• Can a doctor who has been fired in the previous job open his or her clinic?
• The ethical issues behind assisted suicide in hospitals.
• The ethical challenges found in family-making.
• Biomedical ethics is saving the life of an expectant mother.
• The ethical issues to be considered when dealing with HIV/AIDS counseling and testing.
• The possibility of maintaining the confidentiality of medical records in this digitalized world.

Interesting Research Topics for Medical Students

When did you join medical school? How are you fairing on? As a medical student, you need to be ready to read smart to succeed in your studies. Here are some medical research topics that you can study using.

• Is it possible to have a disease-free world?
• How do doctors develop conflicts of interest with patients?
• Should suffering relief be considered in hospitals?
• The best way to deal with religious beliefs that are against science.
• Medical ethics need to be catered for when dealing with mentally challenged individuals.
• The best way to deal with doctors that don’t adhere to office ethics.
• The best way to deal with patients who refuse to undergo an HIV test.
• The duration a doctor should take before reporting an infectious disease.
• Should medical mistakes be considered as any mistakes at work?
• The consequences of a doctor letting a patient die because of ignorance.
• Does lack of trust in families affect the treatment process in hospitals?
• The consequences of a surgeon performing surgery at the wrong place.
• In your view, is human genome editing ethical?
• How to maintain the privacy of patient records using big data.
• How immunization raised ethical issues globally.

Medical Sociology Research Topics

Sociology mainly deals with the study of how people live. It is basically on the socialization of human beings and animals. Hence, medical sociology is an interlink of the two fields in the effort to understand people better.

• The major determinants of health in society.
• The inequalities in access to health care services in different social classes.
• Euthanasia issue from a sociological viewpoint.
• The impact of globalization on the health of the population.
• The impact of all the technological advancements in the medical field.
• How does therapy help in the advancement of the economy in any region?
• The impact of online learning on medical students.
• In your opinion, are medical internships too long for students?
• The effect of long shifts on the mental health of a doctor.
• The importance of dental check-ups.
• Evaluate how memory loss is connected to aging.
• The positive effects of nursing shifts during a pandemic.
• Why is the nursing field not preferred by most men?
• The ethical challenges associated with nursing.
• The effect of the medical field on social interaction.

Medical Microbiology Research Topics

Microbiology is bold and deals with living organisms and biological issues. When you are doing a medical field, you can choose what you want to fully specialize with.

• How does mold grow on things?
• The best preventive measures for sickle cell anemia.
• How do curry and cinnamon inhibit bacterial growth?
• The most harmful effects of mobile radiation.
• The impact of ebola on recent diseases.
• How does cannabis affect the human body?
• The effect of oil spills on water bodies.
• The major causes of eye disorders in children and adolescents.
• When human cloning is done, does it create another you?
• The methods used to erase and implant human memory.
• The major causes of ozone depletion.
• How is autopsy used to determine the death of a person?
• The sub-classification of cirrhosis.
• The effect of acute respiratory diseases on individuals.
• The structure and mechanisms of popular bacteria.

Unique Medical-Surgical Research Topics

The surgical research topics can be seen as a bit tougher than other medical fields. However, as long as you understand the concept, you will succeed in doing any of these research topics.

• The role of nurses in the surgical wards.
• Medical-surgical nursing as an integrated medical approach.
• The standardization of fast-track surgical nursing care.
• The continuity of care post-surgery in community health care.
• Assessment of family satisfaction with care among family members of patients in neurosurgery ICU.
• Patient satisfaction of nursing care in medical wards.
• The influence of self-care programs on self-care cognition.
• The effectiveness of relaxation technique on minimizing post-operative pain in the hospital.
• Nurse’s performance in controlling complications for patients undergoing hemodialysis.
• The risk of patients getting affected while treating COVID 19 patients.
• The critical analysis of community nursing and health care needs.
• The impact of monitoring labor using the partogram and its effect on labor outcome.
• The neurological indications for mechanical ventilation.
• The major causes of ventilatory insufficiency.
• The major causes for the impaired level of consciousness.

Current Medical Research Topics

The medical field keeps evolving as more diseases and infections are discovered. These are some of the most current medical research topics that you can ever come across.

• How does a brain tumor affect the proper functioning of the body?
• The effect of caffeine addiction.
• The best liver and pancreas disease research.
• The neurovascular and spine inventions in the medical field.
• The major causes of acute respiratory failure.
• The major causes of acute respiratory distress syndrome.
• The ethical aspects of medical research in animals.
• The possible medicine developments in the future.
• The impact genetic engineering and cloning will have on mankind.
• The paramedics in health care settings.
• The effect of anorexia and bulimia eating disorders.
• How is assisted suicide a way of treating terminal diseases?
• The role of a healthy diet in the overall health level.
• Comparison between artificial and coma.
• The influence of modern lifestyle on people’s health.

Controversial Medical Research Topics

These are some of the most controversial medical research topics that you can ever come across. They are based on the common phenomenon in the world. Even if you are looking for the best research topics in medical biochemistry, these can suit you.

• The consequences of modern lifestyle upon people’s health.
• The influence of aging on physical and mental health.
• The effect of substance abuse on the human body.
• Is it possible to battle Alzheimer’s disease?
• Is autism a disease or variant of the norm?
• The role of antibiotics in treating diseases.
• The correlation between genetics and nutrition.
• The genetics behind coronary artery disease.
• The genetic factors of Tourette’s disorder.
• The genetic aspects of cerebral palsy.
• The concepts are based on social anxiety disorder.
• Eye complications related to measles in children.
• The risk factors of meningitis in children.
• The prevention strategies for children with obesity.
• The major advantages and disadvantages of breastfeeding.
• The major causes of eating disorders in children.
• The best way to measure neuromuscular and musculoskeletal function.
• The part of the brain associated with communication difficulties
• The effects of stroke on the body.

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• Open access
• Published: 26 April 2024

Why are medical students so motivated to learn ultrasound skills? A qualitative study

• Anina Pless 1   na1 ,
• Roman Hari 1   na1 &
• Michael Harris 1 , 2  

BMC Medical Education volume  24 , Article number:  458 ( 2024 ) Cite this article

Metrics details

The introduction of ultrasound (US) courses into medical undergraduate courses is usually met with a particularly high level of student motivation. The reasons for this are unclear. The aim of this study was to investigate the factors that contribute to undergraduate medical students’ motivation to learn US skills. Understanding what motivates students to learn US will inform the efforts of faculty to foster students’ motivation to learn.

We carried out in-depth semi-structured one-to-one interviews with medical students participating in an optional US course at two Swiss universities. The interview guide consisted of 10 main questions. The content was informed by experts in the field of medical education and US, as well as by a literature review of motivation theories for learning, in particular by self-determination theory (SDT). SDT was used to guide the development of the interview guide and to reflect on the resulting themes in the discussion section. The interview guide was piloted with two medical students. The interviews lasted an average of 45 min and were audio recorded and transcribed. Thematic analysis was used to analyse the data.

Fourteen undergraduate medical students in their preclinical (year 3) and clinical studies (years 4 and 5) elaborated on a wide range of reasons for their high motivation to learn US. They were motivated for US training because of the positive nimbus of the US modality, emphasising the advantages of visualisation. Students acknowledged the potential professional benefits of learning US and described it as a fun, exciting group activity.

Conclusions

The four themes we found in our analysis can all be related to the three universal needs described in SDT. The strong focus on the visual aspect and the positive nimbus of the modality goes beyond that and reflects the visuo-centric Zeitgeist, which claims the superiority of visual information over other data. Educators should be aware that motivation to learn is affected by the Zeitgeist and ensuing preconceptions, such as the perception of the positive nimbus surrounding a topic. Other key elements that can be implemented to motivate students are just-in-time feedback, enabling group experiences and creating awareness of the clinical relevance of learning content.

Peer Review reports

The introduction of mandatory ultrasound (US) courses at our University was greeted with a standing ovation. This is not the usual reaction to the implementation of new courses and is worth exploring. We hope to understand factors that contribute to students’ motivation for learning to foster such factors when teaching.

High levels of motivation correlate with better grades throughout medical studies [ 1 , 2 ]. Kusurkar et al. examined “the effect of quality of motivation on performance” and found that motivation stemming from personal interest positively affects academic performance [ 3 ]. There is a positive correlation between motivation from personal interest and the intention to continue ones studies [ 1 ]. Motivation seems also to be correlated with learners’ well-being [ 4 ].

Several theories try to explain why students are motivated to learn. According to Self-determination theory (SDT), developed by Deci and Ryan, motivation varies not only in quantity but also in quality [ 5 ]. A central idea of the theory is that there is a distinction between autonomous motivation and controlled motivation. Autonomous motivation can be defined as engaging in an activity because one finds it interesting: doing something of one’s own free will. Controlled motivation is the norm, especially after early childhood, when social demands and roles require individuals to take responsibility for non-intrinsically interesting tasks. Students’ motivation to learn ultrasound, as perceived in our experience and as described in the literature, would mainly be classified as “autonomous” motivation in SDT, as they are engaging in an activity that they find interesting [ 6 , 7 , 8 ]. Three universal psychological needs add to the autonomous motivation: autonomy (being free to choose whatever one considers useful to do), competence (the desire to master a task and to feel effective) and relatedness (the feeling of wanting to connect with others and have a sense of belonging) [ 8 , 9 ]. Figure  1 depicts states of motivated behaviour and its relation to autonomy, competence and relatedness. At one end of the continuum is amotivation, the state of lacking an intention to act. When amotivated, people either do not act at all or they act without purpose. Amotivation results from not appreciating an activity, not feeling competent to do it, or not expecting it to achieve a desired outcome. Intrinsic motivation is placed at the other end of the continuum, emphasising that it is the essential form of self-determined activity, based solely on an internal desire to act. Extrinsically motivated behaviours cover the states between amotivation and intrinsic motivation, varying in the extent to which their regulation is autonomous [ 7 ].

The Self-Determination Continuum, adapted from Ryan and Deci, 2000, Cook and Artino, 2016 and ten Cate et al., 2011

Our observation of students’ reception of the implementation of US teaching is in line with recent evidence [ 10 ]. Evaluations of US training programmes report positive feedback from over 95% of students, approval rates rarely seen in other fields of medical education [ 11 , 12 ]. In a USA study, 97% of students agreed that it was important for them to learn basic US skills during medical school [ 13 ]. A German questionnaire study of medical students found a similar number (98.2%) reporting a high or very high interest in curricular US in medical education, with the large majority (94.4%) of respondents agreeing or strongly agreeing that US education should be a mandatory part of their curriculum [ 14 ]. In another study, a large majority of teachers (97%) felt that the students were interested in the course [ 15 ]. Another development that underlines the attractiveness of US education for students is the introduction of extracurricular, student-led peer-tutoring initiatives [ 16 ].

The scarce evidence on why students are motivated to learn US skills, suggests that they believe that US education helps them to be prepared for clinical practice before and after graduation [ 14 , 17 ]. They also describe educational benefits beyond the mastering of US skills, for example learning physical examination skills or improving their understanding of anatomy and physiology [ 11 , 13 , 14 , 18 ]. In a recent study, Wang et al. explored why pre-clinical medical students wanted to learn US by applying Existence, Relatedness and Growth Theory, a model with three categories often used for analysing employee work performance. Students gave reasons related to all three categories, foremost existence needs (e.g. future work requirement) and growth needs (e.g. improving diagnostic skills), with relatedness needs being mentioned less often [ 19 ]. Given SDT’s three basic psychological needs of autonomy, competence and relatedness, the spectrum of reasons is likely to be broader than this.

The aim of this study was to investigate the factors that contribute to undergraduate medical students’ motivation to learn US skills, using SDT as a conceptual framework.

Study design

This was a qualitative study following a constructivist paradigm. We used semi-structured one-to-one interviews to allow the exploration of sensitive topics and motivators. We used thematic analysis to analyse the data [ 20 , 21 ]. We adhered to the Consolidated Criteria for Reporting Qualitative Research Checklist (COREQ) in the reporting of this study (for full COREQ checklist see supplementary Appendix 1) [ 22 ].

Study setting and participants

We interviewed 14 medical students from two different Swiss medical schools (University of Bern, University of Zurich) between 2019 and 2022. Both Universities had developed identical, optional medical student courses in abdominal US education that used volunteer peer-tutors. The blended learning programme was available to all Swiss medical students. The ultrasound course curriculum for the students consisted of five modules, with five hours of e-learning and 16 hours of peer-led tutoring. After completing a summative practical assessment, participants could obtain an internationally recognised course certificate in abdominal ultrasound [ 23 ]. Approximately 20% of medical students participated in these courses.

Recruitment and sampling method

We used purposive sampling. We contacted all the students that were enrolled in a voluntary, extracurricular US course ( n  = 95). Potential participants were invited by an email forwarded to them by the course organisers and were also approached directly at US courses. While we had aimed to stratify participants with regards to gender, University site and age, recruitment was difficult during the COVID-19 pandemic, so we interviewed all the students willing to participate. All the students who agreed to take part had already participated in at least two tutored sessions and gave written, informed consent. After initial contact had been made, none of the participants declined to take part in the study or dropped out of it.

Ethical considerations

The study was submitted to the regional ethics committee which stated that the study does not fall under the Swiss Human Research Act (BASEC-Nr. Req-2018-00059).

All participants gave written informed consent. To ensure participant anonymity, each participant was identified only by a code after interview transcription.

Development of the interview guide

The semi-structured interview guide was informed by a literature review of motivation theories for learning, in particular by SDT, and discussions with faculty who are involved in US education, including medical educators, clinicians and US experts. Based on this information the research team discussed how to phrase questions that would be broad enough to encompass a variety of factors which can contribute to motivation according to SDT [ 7 , 9 ]. The interview guide consisted of 10 main questions which focussed on participants’ reasons to learn US and the perceived benefits (see Appendix 2). Each main question had probes to get more in-depth information. The interview guide was piloted with two students, and changes were made where necessary.

Data collection

All 14 interviews were carried out by the lead researcher AP, who had no prior relationship with the participants and was not affiliated with the US course. The interviewees were told that AP had an interest in their views of learning US skills. The risk of respondent bias, in this case the tendency to give socially desirable answers, was minimised by careful question design. The interviewer was not much older than the participants, preventing a feeling of hierarchy. Only the interviewee and AP were present during the interviews, which lasted an average of 45 min and were audio-recorded. Short field notes were made after each interview, commenting on the mood of the interview and reflecting the interviewer’s role and potential influence. The interviews were conducted at a location of the participants’ choice, most often at a public venue or at the University. Interviews were conducted in Swiss German and transcribed verbatim using High German diction. The transcriptions were done by AP as well as BB and KL, two medical students, all of whom are native Swiss German speakers. We wrote and used a transcription manual to ensure that transcripts were consistent. No repeat interviews were carried out and interview transcripts were not returned to the participants. Analysis was conducted using the High German transcripts.

Data analysis

AP, a medical doctor as well as a medical educator, did the primary analysis. She and MH, an experienced medical doctor, medical educator and qualitative researcher, independently coded three of the transcripts and compared their results to look for inconsistencies. Throughout the process, data was read and reread, using constant comparison with earlier data. Themes which derived from the data were labelled using a process of open coding to identify and later categorise phenomena in the data [ 24 ]. The interviews and analysis of the data were carried out in iterative cycles, going back and forth between the data gathering and analysis, allowing for new insights to inform changes to the interview guide [ 20 , 25 ]. Both coders regularly revised and refined the codes. No software was used.

After 14 interviews, the question of data saturation was discussed among the research team (AP, MH, RH, BB). As no new themes were arising, it was agreed that data saturation had been achieved [ 26 ].

The research team reviewed the findings individually then met to discuss the thematic structure. Each member of the team first presented their initial thoughts as to the themes. The team identified and continuously reviewed the themes until there was consensus [ 21 ]. For the sake of clarity and focus, the analysis focused on ultrasound-related factors and excluded themes related to course design in general.

We sent an overview of the key themes to four of the participants and asked for their comments. No changes needed to be made as a result of this.

14 students participated in the interviews. Table  1 shows participants’ characteristics.

We identified four US-specific themes that contribute to high levels of motivation to learn US skills. Table  2 shows the themes and subthemes.

The themes and subthemes are described in more detail below, with quotations identified by participant number.

Perception of professional benefits

All participants expressed that learning US would be an advantage professionally. This could be during their studies, or as practicing physicians. Learning US as early as possible was seen as adding to this benefit.

Benefits as a medical student

Some participants wanted to understand US images shown in lectures: Now, if we now have an US image in a lecture, I think “yes, ok, I can follow now”. (Participant(P)6)

For most participants, revising and deepening their knowledge of anatomy, as well as applying that knowledge to the patient’s body, were key benefits and motivators. Many participants felt learning US improved their spatial thinking: US gives you a different feeling of the relationships between the organs in the body. And uh, somehow you really know where the kidneys are or where the liver is. (P9)

One participant appreciated that US also put into perspective what was clinically relevant for their future career: And it was always reassuring for me that “yes, what is really relevant, I know” and if I no longer have the twenty-seventh branch of this artery in my head (…) so I was able to put in perspective the anatomical knowledge. For my future medical career. (P9)

Benefits as a physician

All participants stated that having US skills could be relevant to their future as physicians. They thought it was important to understand the indications and be able to interpret US images. Many participants were certain US would be part of their clinical life. One participant stated: Yes, it is also an examination method that is actually used in many disciplines. That means that sooner or later I will be asked to perform it on a patient. (P2) Several participants felt that they needed to be well prepared for their transition from student to resident: And that that’s my goal more or less, things that you can already acquire now, that I have them ready at hand. That at least that will work. (P2) There was also the notion that having US skills would help (…) avoid and reduce unnecessary imaging procedures and refer less patients to specialists. (P6)

The “exciting experience” component

For many participants, the motivation was connected to the feeling of experiencing something inherently fun and exciting: So, yes, it’s also a fascinating, so it’s still a “wow”. A “wow moment”. (laughs) (P3). Participants were intrinsically fascinated with the topic of US and the aspect of visualisation added to this: What I really find interesting is that my fascination still doesn’t let up (…) well, I just found it fascinating to somehow see my own organs for once (laughs). (P9)

The social aspects of learning US

Interpersonal factors played an important role, to learn and interact in small groups with other participants was described as similar to engaging in a new hobby, as well as a way of escaping everyday student life: Um, and what did I always enjoy the most? I think it was simply the interaction with the others. It’s just something that we don’t have much of in our studies. (P9)

While most participants said that the social aspect did not influence the decision to apply for the course, it was important for their positive perception of, and continuing engagement in, the course. They noted that the course gave them the opportunity to meet new people or do something with friends.

A practical skill

Many participants enjoyed doing something practical, as opposed to simply learning theory: Yes, and that’s actually kind of cool. Yeah, not exactly like a surgeon, but still a little bit hands-on. Yes. (P3)

They found learning US also enabled them to put their learning into a clinical perspective, giving them an insight into what they were working towards. One participant described how their US skills helped her become an active member of a clinical team during the practical year: I was allowed to scan a child because I said I had done this course. And afterwards I felt like one of them, not just like a trainee standing at the back, but that I had been fully interactive. (P12)

Learning US as a challenge

Participants found learning US to be a positive challenge: If you just get it or, also with the kidney, if you get it and then you recognize everything, that’s a pleasure. (P11)

Most participants performing US was not a natural gift but something they had to learn, requiring practice, diligence, and effort: Sure, there’s a mega process behind it until it’s intuitive, and it’s not the case with me at all yet, but I can imagine that, that it’s, um, doable with practice. Like the driving test, maybe. (P13)

The positive nimbus of US

Many participants said that they believed US to be an up-and-coming modality in medicine, with many advantages. We summarise these recurrent themes under the concept of the “positive nimbus” of US, referring to its positive image in public and medical discourse.

US as a modern tool

Many participants stated that US was the diagnostic tool of the future, which would become part of every physician’s basic equipment. This was often something that they had heard from others (peers, lecturers, physicians): (…) there was a doctor who said it was super important that you can do it and I should definitely take every opportunity. (P5)

Participants had a positive impression of US as a tool, ascribing many favourable attributes to it, principally that it was fast and easy. The participants found US to be versatile in terms of when and where it could be used (which body part, but also which geographical location), and for which indications to use it. They commented that they were fascinated by the breadth of what can be done with US: Yes, what I find interesting about US is that it can really be used in many different areas. (P7)

Advantages for patients

US as a tool was also described as having advantages for patients because it did not entail radiation, was non-invasive, and not painful. Another benefit for patients was that they could watch the examination “live”: You can show an image directly and that you can say to the patient “there it is and that’s how it is now. It’s good the way it is.” (P7) .

The power of visualisation

One key theme was the appeal of visualising things with US, and this contributed to the positive nimbus of US. For some participants, visualising organs was helpful because it matched their learning style: Well, personally, I’m just very much a visual person. (P8)

Most participants found it impressive to see inside the body and thereby gather a lot of information. It gave them a sense of security and the feeling that US was more objective and precise than other forms of examination: So yes, it seems to me that US is a bit more objective. (P5)

With the help of US, participants were easily able to confirm or exclude pathologies, which they found fascinating. Being able to capture an image was thought to be helpful too: some participants stated that it allowed them to show the image to others if they had any uncertainties, and to check that they had done it correctly: Something that you can see can perhaps be better discussed with other people afterwards. (P8)

Principal findings

In this qualitative interview study, medical students gave a range of reasons for their high motivation to learn US: the positive image surrounding the modality in general, with an emphasis on the advantages of visualisation; they perceived potential professional benefits; and they described it as a fun, exciting activity and a way to interact positively with other learners.

Interpretation of the results

The four themes we identified can be related to the three universal needs of autonomy, competence and relatedness described in SDT.

Mastering US skills contributed to a feeling of competence and autonomy. At the same time, feeling competent in performing US supported students in preparing for their transition from student to resident, giving them confidence in clinical situations and in interactions with patients, thus providing a professional advantage.

Learning US was described as an exciting and fun group activity. This perception aligns with the need for relatedness as described in SDT. The feeling that US was a practical alternation to their theoretical student life and a positive challenge map across to the need for competence.

The idea of learning to use a “modern”, technical tool, gave a feeling of autonomy and competence. Additionally, the fact that US is a mobile device compared to other imaging modalities was seen to offer a high degree of autonomy when deciding when and where to use it.

The visual aspect of US allows for just-in-time feedback and the immediate feeling of success when getting the right image, thus meeting the need for competence.

Whereas all four themes can be linked to the universal needs of SDT, the visual aspect of US and the positive nimbus surrounding US are more related to the “Zeitgeist”. In our study, participants’ comments suggested that they associated US with positive attributes and thought it would become increasingly important in the future. The sense that being able to visualise something was superior to other ways of examining– another subtheme we found– was central to this notion.

Comparison with existing literature

Other studies confirm that students believe learning US is an advantage in their medical studies [ 11 , 13 , 14 ]. A cross-sectional survey of graduates confirms that early US training yields physicians who are better prepared to integrate it into clinical practice [ 27 ]. While the transition from medical school to residency differs depending on the national context, it has been described as stressful and challenging in studies from different countries [ 28 , 29 ]. Early exposure to clinical environments in undergraduate years may help reduce the stress of this transition [ 29 ]. Integrating theoretical knowledge into practice in medical education has been an important issue in medical education for over a decade and remains so today. US teaching in undergraduate studies can aid professional identity formation [ 30 ]. Our results correspond with Wang et al.’s findings, that students are motivated to learn ultrasound because they believe it to be a necessity and/or advantage in their future work or current studies and because they want to learn out of interest. Wang et al. point out that relatedness played less of a role for students’ motivation, while in our study relatedness played an important role in the theme of “fun and exciting activity”. One possible explanation for this discrepancy could be that a distinction between motivation to initiate behaviour (e.g. sign up for a course) and to maintain motivation (e.g. stay motivated during the course) is seldom made. Participants in Wang et al’s study were questioned on motivation to initiate US learning, while in our study, participants had already begun or finished the US course and relatedness contributed to continuing motivation during the course but was seldom discussed as a reason for initial interest [ 19 ].

Our participants felt that visualisation enhanced the objectivity and reliability of an examination, providing a feeling of security, corresponding with Feilchenfeld et al.’s statement that “US’s visual evidence is viewed as truth, more accurate (truthful) than clinical information provided via other senses” [ 31 ]. This “Zeitgeist”, the “visuo-centric discourse” which claims the superiority of visual information over other data, may be common among medical students: a paper on body pedagogics states that “oculocentrism” (a perception of superiority of vision over other senses) is typical in Western society, especially in the medical profession [ 32 ]. The current discourse in our (medical) society that seeing is superior to, and more legitimate than, perceiving with other senses and is thus also beneficial for patient care seems to add to the “positive nimbus” of US and has an effect on students’ high motivation to learn the skill [ 26 , 28 ].

This is the first qualitative study designed to study medical students’ motivation for US education. The design of the interview guide and the interpretation of the results were guided by a consistent theoretical framework (SDT). We interviewed participants from two different medical schools. We piloted the interview guides carefully, achieved data saturation and member-checked the findings.

Limitations

Our participants were from a population taking part in a course with no curricular accreditation, making it likely that they had a high degree of motivation. The participants were students who volunteered to take part in the study, resulting in a risk of self-selection bias. We assumed that the students participating in a voluntary course and voluntarily taking part in the study would be especially highly motivated. Because our aim was to explore high levels of motivation for ultrasound, we hypothesise that the sample was in line with our research question. The factors motivating these students may not apply to other students, for example students with low motivation to learn ultrasound. Including a more varied sample might have given us other insights. Due to the COVID-19 pandemic, we could not stratify participants as intended, as US courses were put on hold for some time. Many students were busy with volunteer work at health facilities and may have been less willing to meet face-to-face. However, there was an equal number of participants from both Universities, and the gender distribution approximately reflects the gender distribution in Swiss medical studies. Also, the participants came from a homogenous group, which makes it more likely that the sample was adequate [ 33 ].

Implications for research and practice

Understanding the mechanisms of motivation in medical education helps to create a supportive learning environment and to nurture autonomous motivation. While some of our findings were specific to the modality of US, some can also be applied to other teaching areas:

Visualisation aids learning, providing immediate feedback, a sense of competence and of autonomy, adding to the motivation. For areas where visualisation is not an option, educators should consider using alternative ways to give immediate feedback, when planning educational programmes. This could mean verbally providing immediate and constructive feedback, or using a portfolio to visually track learners’ progress.

Participants found learning US fun and exciting. Not all areas of learning allow for the hands-on experience of US education, but reflecting on where practical aspects can be integrated into teaching and how to challenge students optimally– making tasks not too easy nor too difficult– could enhance students’ motivation. One example is the “gameification” of learning content, which may add to the fun factor. Educators should enable group experiences and interaction when possible. This could be supported by encouraging students to actively participate in group work, giving a structure to educational units, while also providing enough room to learn in a self-directed way as a group. Facilitators to this can be a setting of mutual trust and open dialogue, and adjusting the learning environment, for example by considering seating arrangements.

Students are motivated to learn things that will benefit them professionally, making awareness of the clinical relevance of learning content essential. Explicitly addressing concerns about transitioning from medical school to residency and providing information on how a specific skill will help for this transition could increase students’ motivation to learn. Pointing out the relevance of the subject to medical practice could help less enthusiastic students see the importance of it and result in a more autonomous– rather than controlled– choice to learn something [ 34 ].

Educators should be aware that learning happens in the context and discourse of society, and that this can affect both educators’ and learners’ perspectives and motivation. While educators cannot influence the discourse directly, it is important to understand its existence, to modify barriers and facilitate motivation. The mechanisms of such discourses and their possible impact on students’ views require more research.

Future quantitative studies could explore to which extent a more general medical student population relates to the identified themes in order to validate them. Including students with low motivation for ultrasound or students with high motivation in other areas as participants and comparing and contrasting these results with those of this study could also provide a more comprehensive view of motivational factors and be an interesting area for further research. Factors which initially sparked participants’ interest and motivation to sign up for the course may be different to those which maintained and increased their motivation during the course. Longitudinal studies would enable a deeper understanding of such nuances and other changes in motivation over time.

We found four themes that have not yet been described in the literature: US was perceived as helpful in contextualising and exemplifying other learning content and supporting the transition into professional identity and, ultimately, clinical practice; the group setting with just-in-time feedback provides a fun and positive learning experience; participants reported being motivated to learn US because it was the tool of the future, and being able to visualise something trumped other forms of examination, reflecting the visuo-centric Zeitgeist. Knowledge and understanding of these themes may be relevant to other areas of medical education.

Data availability

The datasets used and analysed during the current study are available from the corresponding author on reasonable request.

Abbreviations

participant

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Acknowledgements

We thank Benjamin Bulling for his literature review of motivation theories and for the transcription of interviews. We thank Katharina Lüscher for the interview transcription.

This research received no external funding.

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Anina Pless, Roman Hari contributed equally to this work.

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Institute of Primary Health Care (BIHAM), University of Bern, Mittelstrasse 43, 3012, Bern, Switzerland

Anina Pless, Roman Hari & Michael Harris

College of Medicine & Health, University of Exeter Medical School, Exeter, UK

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AP and RH contributed to the conception of the work. AP, RH and MH contributed to the design of the work. AP did the acquisition and primary analysis. AP, MH and RH interpreted the data. AP wrote the main manuscript and MH and RH substantively revised it. All authors have read and approved the final manuscript.

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Pless, A., Hari, R. & Harris, M. Why are medical students so motivated to learn ultrasound skills? A qualitative study. BMC Med Educ 24 , 458 (2024). https://doi.org/10.1186/s12909-024-05420-3

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