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13 Hands-On Bacterial Transformation Activities

January 3, 2023 //  by  Rachel Cruz

Are you looking to teach your secondary students about genetic engineering? This can be a difficult concept to teach but interactive or virtual labs can get them engaged in no time! We have put together thirteen activities about bacterial transformation and DNA recombination to help your students master their microbiology lessons. 

1. Paper Transformation

case study bacterial transformation worksheet

Have students label and visualize the transformation process with this overview of bacterial transformation worksheet. Students will label the functions and structures of common bacteria such as plasmids, DNA, and chromosomes.

Learn More: Teach Engineering

2. Recombinant DNA Board Game

Test your student’s knowledge of cellular transformation and cell growth with this colorful board game. This is also a great activity for reviewing concepts of recombinant DNA and bacterial transformation.

Learn More: Teachers Pay Teachers

3. Create Glowing Bacteria

Want your students to visualize cellular transformation? Then you have to try using E. coli and creating glowing bacteria. 

Learn More: Science Buddies

4. Transforming Bacteria Online Simulation

case study bacterial transformation worksheet

Students get to play the role of scientists in this bacterial transformation simulation. They will be tasked with setting the appropriate temperatures and identifying various bacteria from a selection of test tubes. 

Learn More: Lab Xchange

5. Recombinant DNA

Take your students through a recombinant DNA activity with this fantastic lesson. The hands-on worksheets are accompanied by online visuals to help reinforce their learning. 

Learn More: Texas Instruments

6. DNA Recombinant Paper Plasmids

Looking for a hands-on activity? Then use paper plasmids to teach DNA recombination! This low-prep activity will show how DNA changes and transforms to create new genes.

Learn More: Curious Moranland

7. Make A Plasmid

case study bacterial transformation worksheet

Create plasmids with this easy activity requiring only tape! Students will be able to use these plasmids for further activities from the website which walks them through the intricate process of cellular transformation.

Learn More: Learning Undefeated

8. Bacterial Transformation Lab

This bacterial transformation lab is perfect for high school students learning about all the changes that these single-celled organisms undergo. The package comes complete with lessons, materials, and a guidebook for teachers!

Learn More: School Specialty

9. Bacterial Transformation Virtual Lab

case study bacterial transformation worksheet

Are you planning a lesson on insulin and bacterial transformation? Then extend your student’s learning with this engaging virtual lab. Students will compare the human insulin gene and an antibiotic resistance gene to learn about the various changes involved in their development. 

Learn More: Study.com

10. Lab Reports

Teach your students all about biotechnology with this pGLO bacterial transformation lab! Students will need to write a lab report as they complete the process, and will learn all about the role of plasmids in creating glowing bacteria.

11. Transforming Bacteria To Make Colored Pigments

If you have already completed the glowing bacteria lab, then why not take it a step further by transforming your microbes to create colored pigments? Students will label controls and variables, and work hands-on in this fun lab.

12. Cloning DNA Sequences

case study bacterial transformation worksheet

Clone DNA sequences and perform transformations in this awesome activity! Students will go through the process of cellular transformation and outline how reverse transcriptase can be used to replicate DNA.

Learn More: Nagwa

13. Gene Therapy

Teach your students about gene therapy in this inventive activity. Students will apply their knowledge of plasmids, bacteria, transformation, chromosomes, and biological replicates in this challenging, hands-on lab. 

Learn More: DNA Learning Center

  • Biotechnology

Modeling Bacteria Transformation Worksheet

case study bacterial transformation worksheet

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IMAGES

  1. Modeling Bacteria Transformation Worksheet

    case study bacterial transformation worksheet

  2. Copy of Bacteria Transformation Worksheet.docx

    case study bacterial transformation worksheet

  3. Cells Alive Bacterial Cell Worksheet

    case study bacterial transformation worksheet

  4. Lab9 Bacterial Transformation Handout.pdf

    case study bacterial transformation worksheet

  5. Quiz & Worksheet

    case study bacterial transformation worksheet

  6. Modeling Bacteria Transformation Worksheet

    case study bacterial transformation worksheet

VIDEO

  1. 4- Bacterial structure Outside the cell wall

  2. Genetic Recombination in Bacteria: Transformation, Transduction, and Conjugation

  3. AP Biology-Investigation 8-Bacterial Transformation Lab Walkthrough

  4. Lecture 12

  5. Lecture 13

  6. Inside a Bacterial Defense System

COMMENTS

  1. Case study on Bacterial Transformation

    BACTERIAL TRANSFORMATION (H, BIOLOGY) © Learning and Teaching Scotland 2011. CASE STUDY: BACTERIAL TRANSFORMATION (pGLO) In this activity students will learn about the process of moving genes from. one organism to another with the aid of a plasmid and get to practise. techniques used in microbiology.

  2. Bacteria Transformation

    Bacteria are the most common organisms modified by genetic engineers due to the simple structures of bacteria cells compared to those of eukaryotic cells. Engineers are able to add genes to bacteria using recombinant plasmids, which enable the bacteria to produce the desired beneficial proteins. Students use a paper model to simulate this real ...

  3. Classroom Resources

    Use these short, instructional videos to enrich lessons about bacteria, bacterial transformation, and the green fluorescent protein (GFP). pGLO Plasmid Map and Resources Page ... Case Study: A Role for Bacterial Transformation in Controlling Malaria Transmission (PDF 3.3 MB) Case Study: Hacking the Gut Microbiome (PDF 1.5 MB) ...

  4. PDF Modeling Bacteria Transformation Worksheet Answer Key

    Instructions: Using the word choices provided in the boxes, fill in the numbered boxes with the steps of bacteria transformation and the lettered lines with the name of the structure next to it. Word Choices for Letters foreign DNA with desired gene plasmid recombinant DNA plasmid foreign DNA with desired gene recombinant DNA plasmid cut with ...

  5. PDF Big Genetics and Information Transfer 3

    bacterial plasmid-based genetic transformation, enables students to manipulate genetic information in a laboratory setting to understand more fully how DNA operates. In this investigation, students will first acquire the tools to transform E. coli bacteria to express new genetic information using a plasmid system and apply mathematical

  6. PDF Bacterial Transformation Worksheets

    1. What is the name of the scientist who published a study in 1928 on 2 different strains of Pneumococcus bacteria? 2. In the animation there are images of smooth (S) bacteria and rough (R) bacteria. These different types of bacteria are named after their different physical traits. Explain how differences in DNA can result in different traits. 3.

  7. Bacterial Transformation Flashcards

    3- Transformation. Bacterial conjugation. DNA is transferred from one bacterial donor ell to recipient cell via "sex pilli". Viral Transduction. DNA is introduced into bacteria by injection from a virus. Transformation. bacterial process by which the bacterial cell takes up naked DNA molecules.

  8. Bacterial Transformation

    A. The bacterial cell is able to transform its chromosomal DNA into RNA. B. The bacterial cell is able to transform DNA from their environment. C. The bacterial cell is able to degrade viral DNA from attacking viruses. D. The bacterial cell is able to take in naked DNA and incorporate that DNA into its genome. E.

  9. Bacterial Transformation Practice Problems

    Worksheet. Mendel's Experiments and Laws (0) Inheritance in Diploids and Haploids (0) ... Bacterial Transformation (0) Bacteriophage Genetics (0) Transduction (0) 6. ... The results of the study showed that 80% of the animals raised on antibiotic-using farms had bacterial infections that were resistant to at least one antibiotic. In contrast ...

  10. Bacterial Transformation

    Problem. The DNA from a bacterium with the genotype a+ b+ c+ is used to transform a bacteria with the genotype a b c. Gene pairs were checked for cotransformation with the following results. Using these results determine which genes are linked. A.

  11. 13 Hands-On Bacterial Transformation Activities

    We have put together thirteen activities about bacterial transformation and DNA recombination to help your students master their microbiology lessons. 1. Paper Transformation. Have students label and visualize the transformation process with this overview of bacterial transformation worksheet. Students will label the functions and structures of ...

  12. PDF pGLO Transformation and Inquiry Kit A ThINQ! Investigation

    Pre-Lab: Prepare Students to Investigate pGLO Bacterial Transformation Having been introduced to the concepts of genes, gene expression, and the process of bacterial transformation, the students in Ms. Z's class are anticipating a laboratory exercise on the same topic. In preparation for the pGLO bacterial transformation lab,

  13. Bio-Rad Bacterial Transformation Worksheets

    The Task You are about to calculate the transformation efficiency, which gives you an indication of how effective you were in getting DNA molecules into bacterial cells. Transformation effi- ciency is a number. It represents the total number of bacterial cells that express the green protein, divided by the amount of DNA used in the experiment.

  14. Case Study: How Do Bacteria Become Resistant?

    Shortly after, S. aureus became resistant to penicillin. During the 1950s, derivatives of penicillin was discovered by pharmaceutical companies that could treat Staphylococcus aureus. The graph below depicts the Spread of Antibiotic-Resistant S. aureus Infections in the United States. Separate curves are shown for bacteria that caused ...

  15. AP Biology Lab- Bacterial Transformation Flashcards

    The pulse creates temporary holes in the cells' plasma membrane, through which DNA can enter. Transformation. occurs when a host organism takes in foreign DNA and expresses the foreign gene. ampR gene. confers resistance to the antibiotic ampicillin. +ampR cells can resist antibiotic. -ampR cells are sensitive and are killed by the antibiotic.

  16. Modeling Bacteria Transformation Worksheet

    Modeling Bacteria Transformation Worksheet Answer Key. DATA and OBSERVATIONS. [ Staple recombinant model here. OVERVIEW of BACTERIA TRANSFORMATION. Instructions: Using the word choices provided in the boxes, fill in the numbered boxes with the steps of bacteria. transformation and the lettered lines with the name of the structure next to it.

  17. Bacterial Transformation Virtual Lab

    A transformation will be successful if some of the bacteria in the experimental group contain plasmids. The bacteria in the control group should have no plasmids, as none were present in the tube. Reflection Answer the multiple choice questions (you have 2 attempts for each).

  18. Quiz & Worksheet

    This quiz/worksheet combo will allow students to test the following skills: Making connections - use understanding of the concept of bacterial transformation. Defining key concepts - ensure that ...

  19. How Do Bacteria Become Resistant Answer Key

    Place the chemical on disks and grow bacteria on agar plates, if the bacteria does not grow near the disks that would suggest the chemical is an antibiotic Consider the data gathered from the frog-skin experiment.

  20. Quiz & Worksheet

    Worksheet. Print Worksheet. 1. Biotech companies have exploited transformation in order to _____. insert and express genes in competent bacteria. increase the rate of cell division. force non ...

  21. Uoh genetic lesson 01 activity 1 worksheetas v3

    Name: Date: Class: Modeling Bacteria Transformation Worksheet Answer Key DATA and OBSERVATIONS [ Staple recombinant model here. ] OVERVIEW of BACTERIA TRANSFORMATION Instructions: Using the word choices provided in the boxes, fill in the numbered boxes with the steps of bacteria transformation and the lettered lines with the name of the structure next to it.

  22. 6784684 1 .docx

    View Assignment - Copy of Bacteria Transformation Worksheet.docx from BIOLOGY 11 at For... assignment. Case Study Recombinant DNA.pdf. The Hong Kong University of Science and Technology. LIFS LIFS-193. molecular biology. DNA. foreign DNA. Case Study Recombinant DNA.pdf.

  23. Bacterial Transformation Lab Report

    The null hypothesis is that the E. Coli bacteria will glow and grow the most under +pGLO with LB/Ara. While the alternative hypothesis is that the E. Coli bacteria will glow, and grow the most under +pGLO with LB/Ara/Amp. Bacterial transformation is crucial for in science because it allows genetically engineered bacteria to produce medicines.