biomedical science thesis topics

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45 Biomedical Research Topics for You

Although choosing relevant biomedical research topics is often an arduous task for many, it shouldn’t be for you. You no longer have to worry as we have provided you with a list of topics in biomedical science in this write-up.

Biomedical research is a broad aspect of science, and it is still evolving. This aspect of science involves a variety of ways to prevent and treat diseases that lead to illness and death in people.

This article contains 45 biomedical topics. The topics were carefully selected to guide you in choosing the right topics. They can be used for presentations, seminars, or research purposes, as the case may be.

So, suppose you need topics in biomedical ethics for papers or biomedical thesis topics for various purposes. In that case, you absolutely have to keep reading! Are you ready to see our list of biomedical topics? Then, let’s roll.

Biomedical Engineering Research Topics

Biomedical engineering is the branch of engineering that deals with providing solutions to problems in medicine and biology. Biomedical engineering research is an advanced area of research. Are you considering taking up research in this direction?

Research topics in this area cannot just be coined while eating pizza. It takes a lot of hard work to think out something meaningful. However, we have made a list for you! Here is a list of biomedical engineering topics!

• How to apply deep learning in biomedical engineering
• Bionics: the latest discoveries and applications
• The techniques of genetic engineering
• The relevance of medical engineering today
• How environmental engineering has affected the world

Biomedical Ethics Topics

There are ethical issues surrounding healthcare delivery, research, biotechnology, and medicine. Biomedical Ethics is fundamental to successful practice experience and is addressed by various disciplines. If you want to research this area, then you do not have to look for topics. Here’s a list of biomedical ethics for paper that you can choose from:

• The fundamentals of a physician-patient relationship
• How to handle disability issues as a health care sector
• Resource allocation and distribution
• All you need to know about coercion, consent, and or vulnerability
• Ethical treatment of subjects or animals in clinical trials

Relevant Biomedical Topics

Topics in Biomedical science are numerous, but not all are relevant today. Since biomedical science is constantly evolving, newer topics are coming up. If you desire in your topic selection, read on. Here is a list of relevant biomedical topics just for you!

• The replacement of gene therapy by gene editing
• Revolution of vaccine development by synthetic biology
• Introduction of artificial blood – the impact on the health sector
• Ten things know about artificial womb
• Transplanted reproductive organs and transgender birth

Biomedical Science Topics

Biomedical science is the aspect of scientific studies that focuses on applying biology and chemistry to health care. This field of science has a broad range of disciplines. If you intend to do research in this field, look at this list of research topics in biomedical science.

• The role of biomechanics in health care delivery
• Importance of biomaterials and regeneration engineering
• The application of cell and molecular engineering to medicine
• The evolution of medical instrumentation and devices
• Neural engineering- the latest discoveries

Seminar Topics for Biomedical Instrumentation

Biomedical science is constantly making progress, especially in the aspect of biomedical instrumentation. This makes it worthy of a seminar presentation in schools where it is taught. However, choosing a biomedical research topic for a biomedical instrumentation seminar may not come easy. This is why we have collated five brilliant topics for biomedical instrumentation just for you. They include:

• Microelectrode in neuro-transplants
• Hyperbaric chamber for oxygen therapy
• How concentric ring electrodes can be used to manage epilepsy
• How electromagnetic interference makes cochlear implants work
• Neuroprosthetics Management using Brain-computer interfaces (BCI)

Biomedical Engineering Topics for Presentation

One of the interesting aspects of biomedical science in biomedical engineering. It is the backbone that gives the biomedical science structure. Are you interested in making presentations about biomedical engineering topics? Or do you need biomedical engineering topics for paper? Get started here! We have compiled a list of biomedical engineering topics for you. Here they are:

• In-the-ear device to control stuttering: the basis of its operation
• How to implement the magnetic navigated catheterization
• Semiconductor-cell interfaces: the rudiments of its application
• The benefits of tissue engineering of muscle
• The benefits of sensitive artificial skin for prosthetic arms

Hot Topics in Biomedical Research

Biomedical research is fun because it is often relatable. As interesting as it seems, choosing a topic for research doesn’t come easy at all. Yet, there are also a lot of trending events around biomedical topics. To simplify your selection process, we have written out a few of them here.

Here are some hot biomedical research topics below.

• What is immunology, and what is the relevance today?
• Regenerative medicine- definition, importance, and application
• Myths about antibiotic resistance
• Vaccine development for COVID-19
• Infectious diseases now and before

Biomedical Research Topics

Biomedical research is an extensive process. It requires a lot of time, dedication, and resources. Getting a topic shouldn’t be added to that list. There are biomedical thesis topics and research topics in biomedical science for you here:

• Air pollution- sources, impact, and prevention
• Covid-19 vaccination- the effect on life expectancy
• Hyper insomnia- what is responsible?
• Alzheimer’s disease- newer treatment approaches
• Introduction of MRI compatible infusion pump

Biomedical Nanotechnology Topics

Biomedical research topics and areas now include nanotechnology. Nanotechnology has extended its tentacles to medicine and has been used to treat cancer successfully. This makes it a good research area. It is good for seminar presentations. Here are some biomedical nanotechnology topics below.

• The uses of functional particles and nanomaterials
• Nanoparticles based drug delivery system
• The incorporation of nanoporous membranes into biomedical devices
• Nanostructured materials for biological sensing
• Nanocrystals- imaging, transportation, and toxicity features

Seeking professional assistance to write your biomedical research or thesis? Look no further! At our reputable writing service, our experienced writers specialize in providing tailored support for the complexities of biomedical research. When you say, “ do my thesis for me ” we’re here to guide you through formulating research questions, conducting literature reviews, and analyzing data sets. Entrust the writing process to our experts while you focus on exploring the frontiers of biomedical research. Contact us today for a meticulously crafted thesis that enhances your chances of success.

We believe you have been thoroughly equipped with a list of biomedical topics. This way, you wouldn’t have to go through the stress of choosing a topic for research, seminars, or other educational purposes. Now that you have the topics at your fingertips make your choice and enjoy!

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Biomedical Research Paper Topics

This page offers students an extensive list of biomedical research paper topics , expert advice on how to choose these topics, and guidance on how to write a compelling biomedical research paper. The guide also introduces the services of iResearchNet, an academic assistance company that caters to the unique needs of each student. Offering expert writers, custom-written works, and a host of other features, iResearchNet provides the tools and support necessary for students to excel in their biomedical research papers.

100 Biomedical Research Paper Topics

Biomedical research is a vibrant field, with an extensive range of topics drawn from various sub-disciplines. It encompasses the study of biological processes, clinical medicine, and even technology and engineering applied to the domain of healthcare. Given the sheer breadth of this field, choosing a specific topic can sometimes be overwhelming. To help you navigate this rich landscape, here is a list of biomedical research paper topics, divided into ten categories, each with ten specific topics.

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1. Genetics and Genomics

• Role of genetics in rare diseases
• Advances in gene editing: CRISPR technology
• Human genome project: findings and implications
• Genetic basis of cancer
• Personalized medicine through genomics
• Epigenetic modifications and disease progression
• Genomic data privacy and ethical implications
• Role of genetics in mental health disorders
• Prenatal genetic screening and ethical considerations
• Gene therapy in rare genetic disorders

2. Bioengineering and Biotechnology

• Tissue engineering in regenerative medicine
• Bioprinting of organs: possibilities and challenges
• Role of nanotechnology in targeted drug delivery
• Biosensors in disease diagnosis
• Bioinformatics in drug discovery
• Development and application of biomaterials
• Bioremediation and environmental cleanup
• Biotechnology in agriculture and food production
• Therapeutic applications of stem cells
• Role of biotechnology in pandemic preparedness

3. Neuroscience and Neurology

• Pathophysiology of Alzheimer’s disease
• Advances in Parkinson’s disease research
• Role of neuroimaging in mental health diagnosis
• Understanding the brain-gut axis
• Neurobiology of addiction
• Role of neuroplasticity in recovery from brain injury
• Sleep disorders and cognitive function
• Brain-computer interfaces: possibilities and ethical issues
• Neural correlates of consciousness
• Epigenetic influence on neurodevelopmental disorders

4. Immunology

• Immune response to COVID-19
• Role of immunotherapy in cancer treatment
• Autoimmune diseases: causes and treatments
• Vaccination and herd immunity
• The hygiene hypothesis and rising allergy prevalence
• Role of gut microbiota in immune function
• Immunosenescence and age-related diseases
• Role of inflammation in chronic diseases
• Advances in HIV/AIDS research
• Immunology of transplantation

5. Cardiovascular Research

• Advances in understanding and treating heart failure
• Role of lifestyle factors in cardiovascular disease
• Cardiovascular disease in women
• Hypertension: causes and treatments
• Pathophysiology of atherosclerosis
• Role of inflammation in heart disease
• Novel biomarkers for cardiovascular disease
• Personalized medicine in cardiology
• Advances in cardiac surgery
• Pediatric cardiovascular diseases

6. Infectious Diseases

• Emerging and re-emerging infectious diseases
• Role of antiviral drugs in managing viral diseases
• Antibiotic resistance: causes and solutions
• Zoonotic diseases and public health
• Role of vaccination in preventing infectious diseases
• Infectious diseases in immunocompromised individuals
• Role of genomic sequencing in tracking disease outbreaks
• HIV/AIDS: prevention and treatment
• Advances in malaria research
• Tuberculosis: challenges in prevention and treatment

7. Aging Research

• Biological mechanisms of aging
• Impact of lifestyle on healthy aging
• Age-related macular degeneration
• Role of genetics in longevity
• Aging and cognitive decline
• Social aspects of aging
• Advances in geriatric medicine
• Aging and the immune system
• Role of physical activity in aging
• Aging and mental health

8. Endocrinology

• Advances in diabetes research
• Obesity: causes and health implications
• Thyroid disorders: causes and treatments
• Role of hormones in mental health
• Endocrine disruptors and human health
• Role of insulin in metabolic syndrome
• Advances in treatment of endocrine disorders
• Hormones and cardiovascular health
• Reproductive endocrinology
• Role of endocrinology in aging

9. Mental Health Research

• Advances in understanding and treating depression
• Impact of stress on mental health
• Advances in understanding and treating schizophrenia
• Child and adolescent mental health
• Mental health in the elderly
• Impact of social media on mental health
• Suicide prevention and mental health services
• Role of psychotherapy in mental health
• Mental health disparities

10. Oncology

• Advances in cancer immunotherapy
• Role of genomics in cancer diagnosis and treatment
• Lifestyle factors and cancer risk
• Early detection and prevention of cancer
• Advances in targeted cancer therapies
• Role of radiation therapy in cancer treatment
• Cancer disparities and social determinants of health
• Pediatric oncology: challenges and advances
• Role of stem cells in cancer
• Cancer survivorship and quality of life

These biomedical research paper topics represent a wide array of studies within the field of biomedical research, providing a robust platform to delve into the intricacies of human health and disease. Each topic offers a unique opportunity to explore the remarkable advancements in biomedical research, contributing to the ongoing quest to enhance human health and wellbeing.

Choosing Biomedical Research Paper Topics

The selection of a suitable topic for your biomedical research paper is a critical initial step that will largely influence the course of your study. The right topic will not only engage your interest but will also be robust enough to contribute to the existing body of knowledge. Here are ten tips to guide you in choosing the best topic for your biomedical research paper.

• Relevance to Your Coursework and Interests: Your topic should align with the courses you have taken or are currently enrolled in. Moreover, a topic that piques your interest will motivate you to delve deeper into research, resulting in a richer, more nuanced paper.
• Feasibility: Consider the practicality of your proposed research. Do you have access to the necessary resources, including the literature, laboratories, or databases needed for your study? Ensure that your topic is one that you can manage given your resources and time constraints.
• Novelty and Originality: While it is essential to ensure your topic aligns with your coursework and is feasible, strive to select a topic that brings a new perspective or fresh insight to your field. Originality enhances the contribution of your research to the broader academic community.
• Scope: A well-defined topic helps maintain a clear focus during your research. Avoid choosing a topic too broad that it becomes unmanageable, or so narrow that it lacks depth. Balancing the scope of your research is key to a successful paper.
• Future Career Goals: Consider how your chosen topic could align with or benefit your future career goals. A topic related to your future interests can provide an early start to your career, showcasing your knowledge in that particular field.
• Available Supervision and Mentoring: If you’re in a setting where you have a mentor or supervisor, choose a topic that fits within their area of expertise. This choice will ensure you have the best possible guidance during your research process.
• Ethical Considerations: Some topics may involve ethical considerations, particularly those involving human subjects, animals, or sensitive data. Make sure your topic is ethically sound and you’re prepared to address any related ethical considerations.
• Potential Impact: Consider the potential impact of your research on the field of biomedical science. The best research often addresses a gap in the current knowledge or has the potential to bring about change in healthcare practices or policies.
• Literature Gap: Literature review can help identify gaps in the existing body of knowledge. Choosing a topic that fills in these gaps can make your research more valuable and unique.
• Flexibility: While it’s essential to start with a clear topic, remain open to slight shifts or changes as your research unfolds. Your research might reveal a different angle or a more exciting question within your chosen field, so stay flexible.

Remember, choosing a topic should be an iterative process, and your initial ideas will likely evolve as you conduct a preliminary literature review and discuss your thoughts with your mentors or peers. The ultimate goal is to choose a topic that you are passionate about, as this passion will drive your work and make the research process more enjoyable and fulfilling.

How to Write a Biomedical Research Paper

Writing a biomedical research paper can be a daunting task. However, with careful planning and strategic execution, the process can be more manageable and rewarding. Below are ten tips to help guide you through the process of writing a biomedical research paper.

• Understand Your Assignment: Before you begin your research or writing, make sure you understand the requirements of your assignment. Know the expected length, due date, formatting style, and any specific sections or components you need to include.
• Thorough Literature Review: A comprehensive literature review allows you to understand the current knowledge in your research area and identify gaps where your research can contribute. It will help you shape your research question and place your work in context.
• Clearly Define Your Research Question: A well-defined research question guides your research and keeps your writing focused. It should be clear, specific, and concise, serving as the backbone of your study.
• Prepare a Detailed Outline: An outline helps organize your thoughts and create a roadmap for your paper. It should include all the sections of your research paper, such as the introduction, methods, results, discussion, and conclusion.
• Follow the IMRaD Structure: Most biomedical research papers follow the IMRaD format—Introduction, Methods, Results, and Discussion. This structure facilitates the orderly and logical presentation of your research.
• Use Clear and Concise Language: Biomedical research papers should be written in a clear and concise manner to ensure the reader understands the research’s purpose, methods, and findings. Avoid unnecessary jargon and ensure that complex ideas are explained clearly.
• Proper Citation and Reference: Always properly cite the sources of information you use in your paper. This not only provides credit where it’s due but also allows your readers to follow your line of research. Be sure to follow the citation style specified in your assignment.
• Discuss the Implications: In your discussion, go beyond simply restating your findings. Discuss the implications of your results, how they relate to previous research, and how they contribute to the existing knowledge in the field.
• Proofread and Edit: Never underestimate the importance of proofreading and editing. Checking for grammatical errors, punctuation mistakes, and clarity of language can enhance the readability of your paper.
• Seek Feedback Before Final Submission: Before submitting your paper, seek feedback from peers, mentors, or supervisors. Fresh eyes can often spot unclear sections or errors that you may have missed.

Writing a biomedical research paper is a significant academic endeavor, but remember that every researcher started where you are right now. It’s a process that requires time, effort, and patience. Remember, the ultimate goal is not just to get a good grade but also to contribute to the vast body of biomedical knowledge.

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• In-Depth Research: Every paper that we produce is founded on the bedrock of extensive and in-depth research. Our writers are committed to exploring a wide range of credible and reputable sources to enrich your paper with diverse viewpoints and comprehensive information. This dedication to rigorous research ensures that your paper is not only thoroughly informed but also accurately referenced, adding to its academic integrity.
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• Top Quality: Quality is the cornerstone of our services at iResearchNet. We believe that each paper we craft should demonstrate a high standard of scholarship. Our writers dedicate their skills and effort to ensure every aspect of your paper, from clarity of language to depth of analysis and precision of information, reflects top-quality work.
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Navigating the complexities of biomedical research can be overwhelming, but with iResearchNet, you don’t have to do it alone. Our dedicated team of professionals is committed to taking the stress out of the writing process, allowing you to focus on your learning. Imagine the relief of knowing your assignment is in the hands of experienced, degree-holding experts who are passionate about your success. With our meticulous research and thorough understanding of biomedical topics, we guarantee a paper that not only meets but surpasses your expectations.

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How to write a Doctoral Thesis

Prof. HR Ahmad, Department of Biological and Biomedical Sciences, The Aga Khan University, Karachi, Pakistan. E-mail: [email protected]

Note: * Ahmad HR. In: Medical Writing. Eds. SA Jawaid, MH Jafary & SJ Zuberi. PMJA, 1997 Ed II: 133-142.

PATIENT care and teaching are rather well established components of our medical career. However, with the passage of time a third component has started to influence our medical culture, namely research. 1 - 4 How to accept this challenge is a question. 5 Indeed, teaching and research form a dialectic unit, meaning that teaching without a research component is like a soup without salt. It is a well-established fact that the research activity of an institution is directly proportional to the number of qualified and committed PhD candidates. An inspiring infrastructure, laboratory facilities and libraries are pre-requisites for a research culture to grow. 6 - 8 This forms the basis of a generation cycle for an institution, so that research activity and its culture continues to grow from one generation to the next. The main objective of doctoral work in biomedical sciences is to develop a galaxy of scientist physicians and surgeons possessing high degree of humility, selflessness and ethical superiority. Such a programme will add a scholastic dimension to the clinical faculty.

Education in how to write a doctoral thesis or dissertation should be a part of the postgraduate curriculum, parallel to the laboratory work and Journal Club activities during the PhD studies and/or residency levels. 9 , 10 The overall structure of a doctoral thesis is internationally standardized. However, it varies in style and quality, depending upon how original the work is, and how much the author has understood the work. Therefore a thorough discussion with supervisor, colleagues and assistance from other authors through correspondence can be useful sources for consultation.

The choice of a topic for a doctoral thesis is a crucial step. It should be determined by scanning the literature whether the topic is original or similar work has already been done even a hundred years ago. It is the responsibility of both the supervisor and the PhD candidate to sort out this problem by continuous use of internet and a library. 11 The work leading to the PhD degree can originate from research in following spheres: 12

• b) Methodology
• c) Diagnostic
• d) Therapeutic and Management
• e) Epidemiology

The availability of internationally standardized methods, as well as research committed supervisors can enable physicians and surgeons to do PhD work in both basic and clinical health sciences. The importance of research in basic health sciences cannot be overemphasized. It is rather the base of the applied sciences. There are many instances where the elucidation of a mechanism involved in a process awaits the development of an adequate methodology. 13 In such a scenario; a new method is like a new eye. Research activity in the field of (a) and (b) illuminates the research directions for (c) (d) and (e). It is worth noting that sometimes important basic questions can come from (e) and stimulate research activity in the domain of basic health sciences. 14 , 15

Types of Doctoral Thesis

TYPE-I: Book Form: a classical style. The blueprint of this form is shown in Table-I .

Type-I: The Classical Book Form

TYPE-II: Cumulative Doctoral thesis: A modem but quite useful practice.

INTRODUCTION

A book containing the pearls of a PhD work has standardized divisions and formats, where the number of pages should be weighted in terms of content rather than container. The book includes summary, introduction, materials and methods, results, discussion, conclusions, references and acknowledgements.

Two exercises are mandatory before starting a PhD programme:

• Literature survey using a regular library hours and internet surfing
• Familiarization with the hands-on-experience of methodology involved in the work
• The importance of a continuous literature survey using library, internet and direct correspondence with authors across the globe in the same field cannot be over-emphasized. The main goal of this exercise is to pinpoint the unresolved problem in the literature. An attempt to solve this problem now becomes the topic of the PhD thesis. All the relevant references should be collected, and carefully preserved in the form of a card system arranged alphabetically according to themes and authors. The introduction of the thesis should be styled like a review article with a critical analysis of the work of authors in the literature. The aims of the present PhD work can then also be addressed in the form of questions. The objectives would then deal with how to achieve the aims of the proposed study.

MATERIALS / SUBJECTS AND METHODS

Now comes the most crucial and functional part of the doctoral work, the materials/subjects and methods section. This part can be considered as the motor of the PhD work. The reliability, sensitivity and specificity of the motor must be checked before embarking on a long journey. Controlling the controls is the best guide for a precise and authentic work. Usually materials and methods contain components such as a description of the species involved, their number, age, weight and anthropometric parameters, types of surgical procedures and anesthesia if applied, and a detailed description of methodology. Continuous or point measurements should be thoroughly described. However, a dynamic method should always be preferred to static one.

The experimental protocol should be designed after a small pilot study, which is especially advisable in research on human subjects. A detailed and well-thought experimental protocol forms the basis of conditions under which the results would be obtained. Any deviation from the experimental protocol will affect the outcome, and the interpretation of results. It may be noted that great discoveries are usually accidental and without a protocol, based merely on careful observation! However, for the sake of a publication, a protocol has to be designed after the discovery. After having described the different phases of the experimental protocol with the help of a schematic diagram e.g., showing variables, time period and interventions, the selection of a statistical method should be discussed. Negative results should not be disregarded because they represent the boundary conditions of positive results. Sometimes the negative results are the real results.

It is usual practice that most PhD candidates start writing the methodological components first. This is followed by writing the results. The pre-requisites for writing results are that all figures, tables, schematic diagrams of methods and a working model should be ready. They should be designed in such a way that the information content of each figure should, when projected as a frame be visually clear to audience viewing it from a distance of about fifty feet. It is often observed that the presenters themselves have difficulty in deciphering a frame of the Power-Point being projected in a conference.

The results of a doctoral thesis should be treated like a bride. The flow of writing results becomes easier if all figures and tables are well prepared. This promotes the train of thoughts required to analyze the data in a quantitative fashion. The golden rule of writing results of a thesis is to describe what the figure shows. No explanation is required. One should avoid writing anything which is not there in a figure. Before writing one should observe each diagram for some time and make a list of observations in the form of key words. The more one has understood the information content of a figure; the better will be the fluency of writing. The interruption of the flow in writing most often indicates that an author has not understood the results. Discussion with colleagues or reference to the literature is the only remedy, and it functions sometimes like a caesarean procedure.

Statistical methods are good devices to test the degree of authenticity and precision of results if appropriately applied. The application of statistical technique in human studies poses difficulties because of large standard deviations. Outliers must be discussed, if they are excluded for the sake of statistical significance. Large standard deviations can be minimized by increasing the number of observations. If a regression analysis is not weighted, it gives faulty information. The correlation coefficient value can change from 0.7 to 0.4 if the regression analysis is weighted using Fisher’s test. The dissection of effect from artifact should be analysed in such a way that the signal to noise ratio of a parameter should be considered. A competent statistician should always be consulted in order to avoid the danger of distortion of results.

The legend of a figure should be well written. It contains a title, a brief description of variables and interventions, the main effect and a concluding remark conveying the original message. The writing of PhD work is further eased by a well maintained collection of data in the form of log book, original recordings, analyzed references with summaries and compiling the virgin data of the study on master plan sheet to understand the original signals before submitting to the procedures of statistics. The original data belong to the laboratory of an institution where it came into being and should be preserved for 5-7 years in the archive for the sake of brevity.

This is the liveliest part of a thesis. Its main goal is to defend the work by staging a constructive debate with the literature. The golden rule of this written debate should be that a rigid explanation looks backward and a design looks forward. The object is to derive a model out of a jig-saw puzzle of information. It should be designed in such a way that the results of the present study and those of authors from the literature can be better discussed and interpreted. Agreement and disagreement can be better resolved if one considers under what experimental conditions the results were obtained by the various authors. It means that the boundary conditions for each result should be carefully analyzed and compared.

The discussion can be divided into the following parts:

• criticism of material/subjects and methods
• a list of important observations of the present study
• interpretation and comparison of results of other authors using a literature table
• design of a model
• claim of an original research work
• The criticism of the methodological procedure enables a candidate to demonstrate how precisely the research work has been carried out. The interpretation of results depends critically on the strict experimental protocol and methods. For example, an epidemiological work is a study of a population. However, if the population sampling is done regularly at a specific location; the question arises as to how a result derived from a localized place can be applied to the whole population.
• After having discussed at length the strong and weak points of material/subjects and methods, one should list in a telegraphic design the most important observations of the present study. This may form a good agenda to initiate interpretation, argument, reasoning and comparison with results of other authors. The outcome of this constructive debate should permit the design of a working model in the form of a block diagram. All statements should be very carefully referenced. The ratio of agreement and disagreement should indicate the ability of the author to reconcile conflicting data in an objective and quantitative way. Attempts should be made to design a solution out of the given quantum of information. It is also well known that most of the processes of human physiology can only be understood if their time course is known. The dynamic aspect of interpretation of results is therefore more powerful and superior to the static one. 16 Therefore a continuous record of variables should be preferred and sought to reveal the secrets hidden in the kinetics.
• Finally, the discussion should conclude how far the study was successful in answering the questions being posed at the end of the introduction part. Usually a doctoral thesis raises more questions than it answers. In this way research does not come to a standstill and does become a life time engagement for a committed scientist. Also it is important to note that all scientific theses should be quantifiable and falsifiable, otherwise they lose the spirit and fragrance of a scientific research.
• The author’s claim of original work is finally decided by the critical review of his research work by the literature and the number of times being cited. It can be easily read by a high rate of a citation index of a publication and invitation. When a methodological research clicks, one becomes a star overnight.

Type-II: CUMULATIVE DOCTORAL THESES

Another way of writing a doctoral work is a cumulative type of thesis. 11 It consists of a few original publications in refereed journals of repute. It is supplemented by a concise summary about the research work. This type of thesis is usually practiced in Sweden, Germany and other countries. It has the advantage of being doubly refereed by the journals and the faculty of health sciences. Additionally, papers are published during a doctoral work. A declaration has to be given to the faculty of science about the sharing of research work in publications, provided there are co-authors. The weightage should be in favour of the PhD candidate, so that the thesis can ethically be better defended before the team of august research faculty.

ACKNOWLEDGEMENTS

A critical review of this manuscript by Dr. Roger Sutton, Dr. Khalid Khan, Dr. Bukhtiar Shah and Dr. Satwat Hashmi is gratefully acknowledged.

Dedicated to the memory of Mr. Azim Kidwai for his exemplary academic commitment and devotion to the science journalism in Pakistan.

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Home > Sciences > Biomedical Sciences ETDs

Theses and Dissertations in Biomedical Sciences

Theses/dissertations from 2015 2015.

Dissertation: The Effects of Propofol, Sodium Pentobarbital, and Ketamine Hydrochloride on In Vitro Mouse Embryonic Development , Tyler C. Balak

Dissertation: Investigation Into Protein Folding and Misfolding , Jason Charles Collins

Dissertation: Exploring the Neuropeptides, Neuropeptide Receptors and Neurotransmitter Receptors in the Synganglia of Part-Fed Females of Ornithodoros turicata (Argasidae) and Ixodes scapularis (Ixodidae) with Insights Into Their Roles in Contrasting Biology , Noble I. Egekwu

Theses/Dissertations from 2014 2014

Dissertation: Mouse Oocyte Maturation and Embryo Development After Exposure to Vemurafenib (PLX4032), an Anti-Melanoma B-RAF V600E Inhibitor , Bo Liu

Dissertation: Experimental and Computational Analysis of the Synucleins , Agatha Munyanyi

Theses/Dissertations from 2013 2013

Dissertation: New Tools for Real-Time Study of Embryonic Development , Lauren M. Browning

Dissertation: Structural and Functional Study of Multidrug Membrane Transporters , Feng Ding

Dissertation: Attachment Ability and Melanoma Inhibitory Activity mRNA Expression Level Changes in Murine B16-F10 Melanoma Cells Post Nanosecond Electric Pulses , Hongxia Jia

Dissertation: New Types of Morpho-Physiological Changes in Cells Exposed to Nanosecond Pulsed Electric Field , Mikhail A. Rassokhin

Theses/Dissertations from 2012 2012

Dissertation: Nano- and Micro-Second Electrical Pulsing of B16-F10 Mouse Melanoma Cells: Plasma Membrane and Sub-Cellular Organelle Changes , Yiling Chen

Dissertation: Treatment of Aortic Heart Valve Conduit with Glutamine and Heat Shock as a Means to Deter the Constituent Cellular Population From Becoming Apoptotic , Alyce Marie Linthurst Jones

Dissertation: Design of In Vivo Assays for Study of Transport, Biocompatibility and Toxicity of Nanoparticles , Kerry Jean Lee

Dissertation: The Dietary Isoprenoid Perillyl Alcohol Inhibits Telomerase Activity in Prostate Cancer Cells , Tabetha Sundin

Theses/Dissertations from 2011 2011

Dissertation: Age-Related Hamster Mitochondrial Changes and Oocyte Changes Following Autologous Platelet Mitochondrial Microinjection , Fang Li

Dissertation: Nanosecond Pulsed Electric Field Induction of Programmed Cell Death Is Cell Type Dependent: An in vitro Study , Wei Ren

Dissertation: Altering Nitric Oxide Bioavailability and Lipid Profiles in Endothelial Cells By Polycyclic Aromatic Hydrocarbons in Particulate Matter , Liang Yu

Theses/Dissertations from 2010 2010

Dissertation: Group II Metabolic Glutamate Receptors in the Basal Amygdala Regulate Sleep and Fear-Induced Alterations in Sleep , Enheng Dong

Dissertation: Organization of Human Sperm Chromosomes During Pronuclei Formation , Estella Jones

Dissertation: Cellular Immunity in Mouse Models of Viral Encephalitis , Christina Dawn Steel

Dissertation: The Effects of Cocaine and Ecstasy on Cardiac Myocytes and the Intact Myocardium , David A. Tiangco

Dissertation: Characterization of Metastasis-Associated Cell Surface Glycoproteins in Prostate Cancer , Lifang Yang

Theses/Dissertations from 2009 2009

Dissertation: Mechanisms of Regulation of Proximal Tubule Sodium Transporters in Obesity-Induced Hypertension , Marta A. Ambrozewicz

Dissertation: Comparison of Immune Correlates, Age Related Changes and Proteomic Profiling of Healthy Individuals Receiving Influenza Vaccines , Gaurav Basu

Dissertation: Study of the DNA Damage Complexes Within the HTLV-1 Tax Oncoprotein Interactome , Sidi Mehdi Belgnaoui

Dissertation: Interdependent Regulation of Cytomegalovirus Proteins in Complex , Lisa L. Bolin

Dissertation: Role of the Human Cytomegalovirus IE2 Protein on Transcriptional Regulation of Viral Promoters , Siabhon Michelle Harris

Dissertation: Phosphorylation of the Estrogen Receptor Alpha (ERα) at Serine 118 by Phospho-p44/42 MAPK and Regulation by Estrogen and Progesterone in Human Uterine Leiomyoma Tissue and Cells , Tonia Lakisha Hermon

Dissertation: Effects of HZE Irradiation on Chemical Neurotransmission in Rodent Hippocampus , Mayumi Machida

Dissertation: Molecular Dynamics Study of Single Stranded Peptide Nucleic Acids , Anna K. Manukyan

Dissertation: Computational Studies on R67 Dihydrofolate Reductase: An Investigation Into Its Unique Binding Patterns , Chuanyin Shi

Dissertation: Analysis of N-Linked Oligosaccharides of Prostate-Specific Antigen and Prostatic Acid Phosphatase in Prostatic Fluids , Krista Yaudes White

Theses/Dissertations from 2008 2008

Dissertation: MALDI Mass Spectrometry Imaging for the Discovery of Prostate Carcinoma Biomarkers , Lisa Harris Cazares

Dissertation: In Vivo Murine Melanoma Tumor Responses to Nanosecond Pulsed Electric Field Treatment , Xinhua Chen

Dissertation: Nanosecond Pulsed Electric Fields Induce a Mitochondria-Independent Apoptosis in B16F10 Melanoma Cells In Vitro , Wentia Elissa Ford

Dissertation: Subcellular Localization of Human T-cell Leukemia Virus Type 1 Tax Oncoprotein , Kimberly Anne Fryrear

Dissertation: The Application of Innovative High-Throughput Techniques to Serum Biomarker Discovery , Izabela Debkiewicz Karbassi

Dissertation: PGE2 Receptor Subsets Mediate HCG Regulation of the Plasminogen Activator/Plasmin System in Primate Periovulatory Follicles , Nune Markosyan

Dissertation: Cannabinoids: A Novel Treatment Strategy for Retinal Neurodegenerative Disorders , Sandeep Samudre

Dissertation: Gene Therapy Using Tet-Repressor System to Modulate Prostate Tumor Microenvironment , Nazita Yousefieh

Theses/Dissertations from 2007 2007

Dissertation: Down-Regulation of Natural Killer Cell Activation in Response to Influenza Virus in Older Adults , Yu Jing

Dissertation: Serotype Association and Regulation of the Hyaluronate Lyase Gene of Streptococcus pyogenes , Martha Stokes

Theses/Dissertations from 2006 2006

Dissertation: Extracellular Superoxide Dismutase Protects Cardiomyocytes During Hyperoxia , Mervat Elsayed Ali

Dissertation: Isolation and Functional Mapping of Human T-Cell Leukemia Virus Type 1 Tax Oncoprotein DNA-Damage Complexes , Sarah Saionz Durkin

Dissertation: Nanosecond Pulsed Electric Field Effects on Cell Cycle and Apoptosis , Emily H. Hall

Dissertation: Structure-Function Studies of the cAMP-Dependent Protein Kinase In Vitro and in Intact Cells , Gary Z. Morris

Dissertation: Modulation of TGFβ-Induced PAI -1 Expression by Changes in Actin Polymerization in Human Mesangial Cells , Keyur Patel

Dissertation: Cellular Mechanism of Arglabin-Dimethylaminohydrochloride Cytotoxicity , Xiaofei Qin

Dissertation: The Study of Nitric Oxide Synthase Expression, Function, and Regulation in the Renal Vasculature During Postnatal Renal Development , Brian Blake Ratliff

Dissertation: The Use of Proteomic Technologies to Identify Serum Glycoproteins for the Early Detection of Liver and Prostate Cancers , Elizabeth Ellen Schwegler

Dissertation: Diverse Effects of Nanosecond Pulsed Electric Fields on Mammalian Cells , Jody Anne White

Theses/Dissertations from 2005 2005

Dissertation: Mechanisms of Cell Death Initiated in Herpes Simplex Virus Thymidine Kinase Expressing Colon Tumor Cells Treated with Ganciclovir and UCN-01 , Christina Elizabeth Ahn

Dissertation: Regulation of SPARC Gene Expression by the Activator Protein 1 Transcription Factor , Joseph William Briggs

Dissertation: Defensin in the Ticks Dermacentor variabilis and Ixodes scapularis , Shane Michael Ceraul

Dissertation: Developing and Optimizing Conditions for Single Cell Genetic Analysis , Susan Adele Gitlin

Dissertation: Tumor Response TCF-4/β-Catenin Regulatory Elements for Enhancing Cancer Gene Therapies , Saurabh Kumar Gupta

Dissertation: The Antitumor Agent, Arglabin-DMA, Preferentially Induces Apoptosis in Human Colon Tumor Cells , Sung Wook Kwon

Theses/Dissertations from 2004 2004

Dissertation: The Ultrastructure of the Olfactory System in Two Species of Short-Tailed Shrews, Blarina brevicauda and Blarina carolinensis , Lisa Johnson Byrum

Theses/Dissertations from 2003 2003

Dissertation: Characterization of Mouse Prostate Tumor-Infiltrating Leukocytes , Daniel Alan Holterman

Dissertation: The Quantitative Assessment of Osteoinductivity of Human Demineralized Bone Matrix and cDNA Array Analysis of Osteogenic Differentiation in Human Periosteal Cells , Sittisak Honsawek

Dissertation: Embryo and Gamete Development Upon Exposure to CCA Components: CrO3, CuO, and AS2O5 , Nerbana Talaat-Elsebaei Mahmoud

Dissertation: K+-Induced Smooth Muscle Calcium Sensitization Requires RhoA Kinase (ROK) Translocation to Caveolae Which Is Inhibited in Non-Neuronal Cell Memory , Nicole Hairrell Urban

Dissertation: Hyaluronate Lyase Gene of Streptococcus pyogenes : Molecular Characterization and Regulation , Sheryl Lynne Walton

Theses/Dissertations from 2002 2002

Dissertation: Involvement of Platelet-Derived Growth Factor, PDGF Receptor Signaling, Focal Adhesion Kinase and SRC in Pressure-Induced Vascular Smooth Muscle Hypertrophy , Darian Clark Rice

Dissertation: Apoptosis Pathways: Presence and significance in Ejaculated Human Spermatozoa , Steven Lewis Taylor

Dissertation: Prostate Specific Membrane Antigen (PSMA): Immunoassay Development and Characterization of Transcriptional Regulation , Zhen Xiao

Theses/Dissertations from 2001 2001

Dissertation: Detection of Aneuploidy for Chromosomes 7 and 8 Using Fluorescence In Situ Hybridization in Patients with Aplastic Anemia and Sequencing of the Mitotic Checkpoint Gene hBUB1 , Laura Jane Aridgides

Dissertation: Characterization of Murine Cytomegalovirus m142 and m143 Essential Gene Products , Bridget Linette Dalton

Dissertation: Estrogen Regulation of the Pregnant Baboon Placental 11β-Hydroxysteroid Dehydrogenase (11β-HSD)-Catalyzed Metabolism of Cortisol and Cortisone and Its Effect on the Development of the Fetal Hypothalamic-Pituitary-Adrenal Axis , William Adair Davies

Dissertation: Regulation of the HCMV UL98 Promoter by Cooperation of the Cyclic AMP Response Element and Gamma Interferon Response Element , Tabmitha Patricia Young Jervey

Dissertation: Interactions Among Murine Cytomegalovirus US22 Family Gene Products That Influence Viral Pathogenesis , Zaruhi Karabekian

Dissertation: Characterization of the Biological Activities of Recombinant Fusion Protein Green Fluorescent Protein/Human Zona Pellucida Protein 3 (GFP/HZP3) , Zhiyong Lin

Dissertation: Characterization of the Human Cytomegalovirus UL75 Late Gene Promoter , Bernard J. P. McWatters

Theses/Dissertations from 2000 2000

Dissertation: Characterization of Human T-Cell Leukemia Virus 1 Reverse Transcriptase , Pinky Gundayao Agbuya

Dissertation: Mechanistic Characterization of the Mitochondrial Type I DNA Topoisomerase and a Study of Genes Containing Type I DNA Topoisomerase-Related Domains , Jaydee Dones Cabral

Dissertation: Role of Lipolysis and Lipogenesis in the Development of Diet-Induced Obesity , Michael John Davies

Dissertation: Transcriptional Regulation of Chicken Apolipoprotein A-I Gene Expression , Wen Lin Kumfert

Dissertation: Investigations on the Use of Ion Mobility Spectrometry for Clinical Chemistry Applications , Henri Parson Patten

Dissertation: Telomerase Activity in Human Preimplantation Embryos , Diane Lynne Wright

Dissertation: Human Gonadotropin-Releasing Hormone (hGnRH) Gene Expression and Hormone Regulation in Human Placental JEG-3 Cells , Heming Zheng

Theses/Dissertations from 1999 1999

Dissertation: Production of Copper-Complexing Ligands in Response to Elevated Concentrations of Copper in Marine Synechococcus spp. , Arunsri Chatkaeomorakot Brown

Dissertation: Construction of an Escherichia coli lac Repressor-Based System to Study Human Cytomegalovirus Gene Expression , Laura Fernanda Cageao-Luchetti

Dissertation: Tissue-Specific Expression and Steroid Hormone Regulation of Human Gonadotropin -Releasing Hormone (hGnRH) Gene in Placental Cells (JEG -3 cells) , Zhengguang Chen

Dissertation: Identification and Characterization of Determinants of Head and Neck Tumor Cell Invasion , Yangguan Wu

Theses/Dissertations from 1998 1998

Dissertation: Expression, Isolation and Purification of Human Zona Pellucida Protein 3 , Ting-Fung Chi

Dissertation: Characterization of the Biological Functions of Human Recombinant Zona Pellucida Protein 3 , Yu Wen Juan

Dissertation: Pressure-Induced Intracellular Signaling in Isolated Arteries , Victor A. Miriel

Dissertation: Leukemia Inhibitory Factor (LIF): Murine Preimplantation Embryo Development, Implantation Rates, and Skeletal Development , Michael Hayes Mitchell

Dissertation: The Role of Glycoconjugates in Mediating Human Fertilization and Induction of Fetomaternal Tolerance , Manish S. Patankar

Dissertation: Mouse Embryo Development in the Presence of Capsaicin , Carlos Santiago Villar-Gosalvez

Theses/Dissertations from 1997 1997

Dissertation: Differential Endometrial Responses of Primates vs Rodents: Screening for Antiproliferative Effects of Antiprogestins , David Williams Burleigh

Dissertation: Fluorescence in Situ Hybridization Analysis of Human Embryos Derived From in Vitro and in Vivo Matured Oocytes , Constance DeScisciolo

Dissertation: Choline Acetyltransferase and Carnitine Acetyltransferase Activity in Human Spermatozoa During Capacitation , Lisa A. Eccles

Dissertation: Abnormalities in Post-Translational Processing of Platelet Rap 1B in NIDDM: A Possible Cause of Platelet Hyperactivity and Cardiovascular Disease in Diabetes , Elizabeth Ann Hall

Dissertation: Interaction of ACTH and Estradiol in the Regulation of Growth, Differentiation, and Steroidogenic Maturation of the Baboon Fetal Adrenal Gland , Maria Gomez Leavitt

Dissertation: The Cellular and Molecular Dynamics of the Queuosine Modification in Transfer RNA: Definition, Modulation, Deficiencies and Effect of the Queuosine Modification System , Rana C. Morris

Dissertation: Characterization of the Fast Axonally Transported Proteins in the Rat Optic Pathway , Surafel Mulugeta

Dissertation: Arterial Wall Hypertrophy and PDGF-A Expression in One-Kidney, One-Clip Hypertension and Angiotensin II Infusion Are Mediated By Elevated Arterial Pressure , Sheri Blair Parker

Dissertation: Type II Estrogen Binding-Site Agonist: The Synthesis and Biological Evaluation of the Enantiomers of Methyl-Para-Hydroxyphenyllactate (MeHPLA) , Lester G. Pretlow

Dissertation: The Effects of Estrogen on Dorsal Root Ganglion Neurons , Sheila A. Scoville

Dissertation: Axotomy and Regeneration of the Rat Facial Nerve: A Histomorphometric Study of the Facial Nucleus, Nerve and Orbicularis Oculi Muscle in an Experimental Model of Facial Paralysis , Peter Konstantinos Thanos

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Biomedical Sciences: Theses and Dissertations

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Introduction

Theses and dissertations are documents that present an author's research findings, which are submitted to the University in support of their academic degree. They are very useful to consult when carrying out your own research because they:

• provide a springboard to scope existing literature
• provide inspiration for the finished product
• show you the evolution of an author's ideas over time
• provide relevant and up-to-date research (for recent theses and dissertations)

On this page you will find guidance on how to search for and access theses and dissertations in the Bodleian Libraries and beyond.

Definitions

Terms you may encounter in your research.

Thesis: In the UK, a thesis is normally a document that presents an author's research findings as part of a doctoral or research programme.

Dissertation: In the UK, a dissertation is normally a document that presents an author's research findings as part of an undergraduate or master's programme.

DPhil: An abbreviation for Doctor of Philosophy, which is an advanced research qualification. You may also see it referred to as PhD.

ORA: The Oxford University Research Archive , an institutional repository for the University of Oxford's research output including digital theses.

Theses and dissertations

• Reading theses and dissertations in the Bodleian Libraries

The Bodleian Libraries collection holds DPhil, MLitt and MPhil theses deposited at the University of Oxford, which you can consult. You may also be interested to read theses and dissertations beyond the University of Oxford, some of which can be read online, or you can request an inter-library loan.

Help with theses and dissertations

To find out more about how to find and access theses and dissertations in the Bodleian Libraries and beyond, we recommend the following:

• Bodleian Libraries theses and dissertations Links to information on accessing the Bodleian Libraries collections of Oxford, UK, US and other international theses.
• Oxford University Research Archive guide
• Help & guidance for digital theses Information on copyright, how to deposit your thesis in ORA and other important matters
• Guide to copyright The Bodleian Libraries' Quick guide to copyright and digital sources.

Plagiarism checking tools

Read the University academic good practice page.

Seek your Supervisor or Tutor's guidance. In addition, your Supervisor or Tutor may decide to submit your work to Turnitin, accessible to teaching staff only. Visit the Turnitin website for product information.

Consult books - suggested reading:

• Neville, C. (2016). The complete guide to referencing and avoiding plagiarism (3rd ed.).  Maidenhead: Open University Press. Title available in e-book and print format - shelfmark PN171.F56 NEV 2016 in the Radcliffe Science Library 
• Pears, R. & Shields, G.J. (2019). Cite them right: the essential referencing guide (11th ed.) Basingstoke: Palgrave Macmillan. Title available in e-book format

Depositing your thesis

It is mandatory for students completing a research degree at the University of Oxford (registered to a programme of study on or after 1st October 2007) to deposit an electronic copy of their theses with the Oxford University Research Archive (ORA) in order to meet the requirements of their award. To find out more, visit the Oxford University Research Archive guide.

Quick access to research & writing guides

• Research integrity and ethics The University of Oxford regards research integrity as a core value and has a longstanding commitment to ensuring that it is embedded in its research culture and activity
• Academic good practice Advice on academic good practice including avoiding plagiarism, managing your time, reading, note taking, referencing and revision.
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School of Biomedical Sciences

Biomedical research themes & projects.

The School’s diverse research themes bring together researchers from the social sciences, epidemiology and public health, preventive, clinical and primary care medicine and from basic and applied sciences.

Cancer in Biomedicine

Characterising the molecular mechanisms responsible for cancer progression, predisposition and resistance to treatment.

Cardio-Respiratory

Focusing on the impact of diseases and adverse impact on cardio-respiratory function.

Cell Signalling

Researching cell signaling pathways and their importance in conveying information among cells to assist in understanding the development of a variety of human diseases.

Cellular Imaging & Structural Biology

Applying cellular imaging and structural biology expertise across a wide range of biomedical research programs. Platforms include fluorescence, live imaging, 2-photon imaging, transmission and scanning electron microscopy as well as whole body imaging and imaging mass spectroscopy.

Infection & Immunity

Focusing on the mechanisms of infection and immunity and development of new ways to control and treat infectious diseases - from molecular analysis of bacterial and viral infections to the development and function of the immune system.

Molecular Mechanisms of Disease

Modelling human diseases in experimental systems and analysing cells and tissues to gain insights into the underlying fundamental mechanisms of a range of diseases affecting the nervous system, respiratory system, muscle diseases and infectious disease.

Biomedical Neuroscience

Seeking to understand fundamental biological mechanisms in order to develop new treatments for injury and disease states, across neuroscience, cell and developmental biology, and anatomical sciences.

Characterising cellular and molecular mechanisms that underlie stem cell behaviour in development and disease, leading to the identification and characterisation of innovative biomarkers and therapeutic targets.

Systems Biology

Making quantitative measurements and computational analysis of the interacting components in systems biology using genomics, proteomics, bioinformatics, metabolomics and mass spectrometry.

Therapeutics & Translation

The translation of discoveries in Biomedical Sciences across clinical and commercial settings.

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Bringing together teaching specialists and academics across the School focused on improving student learning, outcomes, experiences and engagement across the biomedical sciences.

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Example Dissertation Titles

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Major subjects

Biochemistry.

Do histone modifications control gene expression?

Does endotoxin cause or contribute to neurodegenerative diseases?

Molecular interactions of drugs with the allosteric sites of vertebrate Cys-loop receptors

Why do bacteria carry toxin-antitoxin systems?

Aneuploidy in cancer: lessons so far

Big data in genomics and healthcare and how it has defined cancer diagnosis and treatment

Modelling in Biology: accurate descriptions of our pathetic thinking or pathetic descriptions of the real world?

Trace the economic and biological causes of the current antibiotic resistance crisis. Is there a solution and, if so, does it lie in the hands of patients, clinicians, regulators or researchers?

Transposable elements – a powerful force driving evolution

Can the gut microbiota influence host appetite? Implications for the aetiology of obesity

Can vaccine innovation solve the last mile problem for vaccines in low-resource settings

Eradication of Polio: Past Challenges and Future Prospects

Is the age of antibiotics over?

Microbiome regulation of the gut-brain axis: implications for anxiety and depression

On the origin of the bacterial flagellum: an example of irreducible complexity?

Recent advances in the blockade of immune checkpoints in cancer immunotherapy

What are the major causes of delay in response to emerging disease outbreaks: the case of the 2014-2016 Ebola outbreak in West Africa

Pharmacology

Cystic-fibrosis related diabetes

How do SNAREs mediate membrane fusion?

Is CRISPR ready for the clinic?

Phantom pain: a ghost in the machine or a biological basis?

Plant-derived polysaccharides - sweet medicine of tomorrow?

Why are opioids problematic analgesics?

Plant Sciences

"Scrambled Genomes": examining the methodology and goals of the Sc2.0 synthetic genome project

Engineering C4 Rice: Molecular Targets and Progress so far

Is Trehalose-6-phosphate a central regulator of plant carbon partitioning?

Sucrose signalling and its role in plant development

Who needs cells anyway?

Is visual adaptation diminished in autism spectrum disorders?

Memory reconsolidation blockade: a novel treatment for Post-Traumatic Stress Disorder

Parental influence on child language development: does gender matter?

Sleep disorders as model for Consciousness Research: a cognitive framework for parasomnias

The role of genetics in the transgenerational transmission of memories

The role of insulin in cognitive decline in the elderly

Physiology, Development and Neuroscience

Adaptations of cancer cells for metastasis to the brain

How and why is the infant gut microbiota affected by caesarean section? The crying need for well-designed research

How do astrocytes support and modulate neuronal function? Exploring neurovascular coupling, neurometabolic coupling, and gliotransmission

The missing nuances of science and society: How popular science is shaping policy and understanding

The role of operant conditioning in spinal cord plasticity and its potential therapeutic implications for spinal cord injury

The significance of proinflammatory mediators in disrupting HRV: a link to cardiovascular morbidity in schizophrenia?

Psychology, Neuroscience and Behaviour

Prenatal stress: relevance to major depressive disorder

Promises and limitations of a combinatorial approach to spinal cord injury

Social neurons? A critical examination of how individual neurons might implement primate social cognition

The bidirectional relationship between the hippocampus and metabolic syndrome

The Cognitive and Neurobiological Benefits of an Imperfect Memory

Why are drug seeking habits maladaptive?

How have homosexual mating preferences evolved in males and females?

How relevant is the Drosophila segmentation paradigm to the study of segmentation in other arthropods and other animals?

Mechanisms of mass extinction

Migration of Homo erectus out of Africa

The meaning of alarm calls: honesty and deception

Wolves verses Eurasian Lynx as candidates for large predator reintroduction in mainland Britain - which may be the most suitable and why?

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Conservation science.

Causes and remedies for the decline in red squirrel numbers in Britain

How do deer impact forest organisms in UK lowland woodland?

Reintroduction and translocation as conservation tools for rhinos

Translocation as a tool for tiger ( Panthera tigris ) conservation: problems and potential solutions

With respect to myxomatosis and RHD virus how have rabbit populations co-evolved with the viruses and how may rabbit populations be affected in the future?

Development and Psychopathology

To what extent have biasing in screening and diagnosis contributed to the sex ratios observed in autism?

Health, Medicine and Society

Medicalisation and violence against women: implications for the medical encounter

Human Ecology and Behaviour

The use of wood in prehistory

Neural Degeneration and Regeneration

Progress towards establishing lead times of biomarkers for early diagnosis of idiopathic Parkinson's disease

The Pharmacological Targeting of the Amyloid-beta pathway in Alzheimer's: issues and prospects

Philosophy and Ethics of Medicine

Dementia: how changing perspectives affect clinical decision making

Should the MMR vaccine be mandatory? The problem of herd immunity threshold

Psychology and Social Issues

Reducing Extremist Violence by increasing Integrative Complexity - why understanding the role of emotion is central to success

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UKnowledge > College of Engineering > Biomedical Engineering > Theses & Dissertations

Theses and Dissertations--Biomedical Engineering

Theses/dissertations from 2024 2024.

DEVELOPING AN IMMUNOMODULATORY STRATEGY USING BIOPHYSICAL CUES TO MODULATE MACROPHAGE PHENOTYPE FOR FRACTURE HEALING AND BONE REGENERATION , Harshini Suresh Kumar

Theses/Dissertations from 2023 2023

A Wearable Fiber-Free Optical Sensor for Continuous Measurements of Cerebral Blood Flow and Oxygenation , Xuhui Liu

3-DIMENSIONAL MUSCLE CONSTRUCTS: USING HYDROGELS IN ORDER TO MODEL THE EFFECTS OF EXERCISE IN DISEASE CONDITIONS , Mark McHargue

MULTISCALE AND MULTIMODALITY OPTICAL IMAGING OF BRAIN HEMODYNAMICS AND FUNCTION , Mehrana Mohtasebi

DEFINING SAGITTAL PLANE GAIT MECHANICS AND JOINT LOADING IN PEOPLE WITH MARFAN SYNDROME , Justin Melan Pol

Theses/Dissertations from 2022 2022

USE OF IMAGE PROCESSING TECHNIQUES AND MACHINE LEARNING FOR BETTER UNDERSTANDING OF T GONDII BIOLOGY , Amer Asiri

An Electrochemical, Fluidic, Chip-Based Biosensor for Biomarker Detection , Lauren Bell

VOLUNTARY CONTROL OF BREATHING ACCORDING TO THE BREATHING PATTERN DURING LISTENING TO MUSIC AND NON-CONTACT MEASUREMENT OF HEART RATE AND RESPIRATION , Dibyajyoti Biswal

Characterizing the Internal Porous Structure of Equine Proximal Sesamoid Bones Subjected to Race Training Using Fast Fourier Transforms , Joseph Erik Davis

Theses/Dissertations from 2021 2021

CHARACTERIZATION OF MODULATION AND COHERENCE IN SENSORIMOTOR RHYTHMS USING DIFFERENT ELECTROENCEPHALOGRAPHIC SIGNAL DERIVATIONS , Stephen Dundon

Analysis of Graded Sensorimotor Rhythms for Brain-Computer Interface Applications , Chase Allen Haddix

NOVEL TOOLS FOR ANALYSIS OF DISORDERED SLEEP AND MOTOR BEHAVIOR IN PRECLINICAL MODELS OF DISEASE , Dillon M. Huffman

CHANGES IN CARDIOVASCULAR, RESPIRATORY, AND NEURAL ACTIVITY BY MUSIC: EFFECTS OF BREATHING PATHWAY ON FEELING EMOTIONS , Mohammad Javad Mollakazemi

Facilitating Analysis of Toxoplasma gondii Bradyzoite Metabolic Activity via Image Processing and Multivariate Logistic Regression for High Throughput Classification of Mitochondrial Morphologies , Brooke Place

WORK-RELATED CHANGES IN THE TRUNK STIFFNESS OF NURSING PERSONNEL , Clare Tyler

Theses/Dissertations from 2020 2020

HIGH FREQUENCY OSCILLATIONS IN THE EPILEPTIC BRAIN: ACCURATE DETECTION, EFFECT OF VIGILANCE STATE, AND SAMPLE SIZE CONSIDERATIONS , Amir Fared Partu Al-Bakri

ATV Dynamics and Pediatric Rider Safety , James T. Auxier II

Assessment of White Matter Hyperintensity, Cerebral Blood Flow, and Cerebral Oxygenation in Older Subjects Stratified by Cerebrovascular Risk , Ahmed A. Bahrani

EFFECTS OF A HIP ORTHOSIS ON LUMBOPELVIC COORDINATION IN INDIVIDUALS WITH AND WITHOUT LOW BACK PAIN , Colin Drury

Noncontact Multiscale Diffuse Optical Imaging of Deep Tissue Hemodynamics in Animals and Humans , Siavash Mazdeyasna

Work Related Diurnal Changes in Trunk Mechanical Behavior , Maeve McDonald

Theses/Dissertations from 2019 2019

A POSSIBLE LINK BETWEEN R-WAVE AMPLITUDE ALTERNANS AND T-WAVE ALTERNANS IN ECGs , Sahar Alaei

BIOMECHANICAL EFFECTS OF A HIP ORTHOSIS ON LUMBO-PELVIC COORDINATION , Matthew Ballard

CALIBRATED SHORT TR RECOVERY MRI FOR RAPID MEASUREMENT OF BRAIN-BLOOD PARTITION COEFFICIENT AND CORRECTION OF QUANTITATIVE CEREBRAL BLOOD FLOW , Scott William Thalman

A BRAIN-COMPUTER INTERFACE FOR CLOSED-LOOP SENSORY STIMULATION DURING MOTOR TRAINING IN PATIENTS WITH TETRAPLEGIA , Sarah Helen Thomas

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Home > USC Columbia > Engineering and Computing, College of > Biomedical Engineering > Biomedical Engineering Theses and Dissertations

Biomedical Engineering Theses and Dissertations

Theses/dissertations from 2023 2023.

Laboratory Management Models in Core Facilities , Karmen Michael Owen

Detecting Physiological Concentrations of Alzheimer’s Associated Amyloid-β Protein Utilizing a Cell-Based Response , Brittany Elizabeth Watson

Volume Change Measurements of Cancer Cells in a Microfluidics Platform , Yukuan Yu

Theses/Dissertations from 2022 2022

Investigating the Impact of Endothelial Dysfunction and Aging On Vascular Remodeling Using Mouse Models , Liya Du

Histomechanical Compatibility of Coronary Artery Bypass Grafts , Colton J. Kostelnik

The Effect of Pulsed Field DC Electrophoresis and Field Amplified Sample Stacking on the Microchip Electrophoretic Separation of Organic Dyes , Travis Geoffrey Stewart

Long Non-coding RNA PVT1 – An Exploratory Study in Ovarian and Endometrial Cancer , Kevin Tabury

Interrogating the Role of ING4 in Hematopoietic Stem Cells and Cancer , Zanshé Thompson

Theses/Dissertations from 2021 2021

An in Vitro Approach To Vascular Therapeutic Testing , Shahd Ali Hasanain

Age and Sex Dependency of Thoracic Aortic Aneurysm Progression in a Mouse Model of Marfan Syndrome , Nazli Gharraee

Impaired Metabolic Flexibility in a Mouse Model Of Leigh Syndrome , Richard Sterling McCain Jr

Vascular Endothelial Dysfunction and Effects on Arterial Wall Microstructure , Jeffrey Thomas Rodgers

The Immune Modulatory Role of Endocannabinoid Anandamide to Suppress Inflammation Through Regulation of Microrna and Microbiome , Muthanna Ali Sultan

Theses/Dissertations from 2020 2020

Advanced Geometric Analyses in Vascular Disease and Interventions , Dara Ahmadi Azar

Nitric Oxide Expression With Age and Diet in the Arterial Wall of Apoe Knockout Mice , Kara Cooper

cis -Resveratrol Upregulates Tyrosyl-tRNA Synthetase and Inhibits the Proliferation of Select Breast Cancer Cell Lines , Marion Cone Hope III

Using Human Granulosa Cells to Select the Most Competent Embryos for Uterine Transfer in in Vitro Fertilization Cycles , Richard John Kordus

Effect of Cannabinoid Treatment on Immune Cell Functions During Acute Lung Injury , Amira Kamil Mohammed

Theses/Dissertations from 2019 2019

Beneficial Effects of Resveratrol Against Colitis and Colorectal Cancer Mediated by the Host Microbiome, Epigenome, and Immune Response , Haider Rasheed Daham Alrafas

Three-Dimensional Plasma Cell Survival Microniche in Multiple Myeloma , Katrina A. Harmon

Adipose Tissue Engineering: A Therapeutic Strategy for the Treatment of Obesity and Glucose Intolerance , Michael A. Hendley

Role of P-Glycoprotein in Alzheimer’s Disease for Enhanced Brain Elimination of Amyloid-β , Hope Holt

Three-Dimensional Collagen Tubes for In Vitro Modeling , Rebecca Jones

Experimental Methods and Techniques for Improved Biomechanical Characterization of Diverse Murine Aortopathies , Brooks Alexander Lane

Experimental Study of Free-Solution Separation Under Pulsed Electrophoresis in Microchip , Xin Liu

Biophysical Analyses of Left Ventricular Remodeling Secondary to Myocardial Infarction and Left Ventricular Pressure Overload , William Manuel Torres

RAGE Expression and Inflammation in Alzheimer’s Disease: in Vitro Model Development and Investigation of a Potential Peptoid Inhibitor , Lauren Michell Wolf

Theses/Dissertations from 2018 2018

Identification of the Mechanisms Through Which Botanicals Attenuate Pathogenesis of Human Diseases , Esraah Alharris

A Comprehensive Reengineering Of The Hospital Emergency Triage System , Nicholas D. Boltin

Matrix Stiffness Modulates Mesenchymal Stem Cell Sensitivity to Geometric Asymmetry Signals , Maria Eugenia Piroli

Association Between Mechanics And Biology In Vascular Graft Remodeling , David Andrew Prim

Modulation Of Amyloid-β Aggregation Via Small Molecules And Glycine Zipper Alterations , Steven Zebulon Vance

Theses/Dissertations from 2017 2017

Atherosclerotic Plaque Adhesion Strength and its role in Plaque Rupture , Bilal Merei

Far-Field Optical Microscopy Based on Stimulated Emission Depletion , Yunxia Wang

Theses/Dissertations from 2016 2016

A Theoretical Study of Polymer based Drug Delivery Systems , Ebtisam Abdullatif Aldaais

Automated Image Analysis And Spatial Computational Modeling Of NF-kB In Cerebrovascular Endothelial Cells , Kasey Catalfomo

Therapeutic Potential Of Catechins And Derivatives For The Prevention Of Alzheimer’s Disease , Shelby Elaine Chastain

A Mechanical Approach to the Characterization of Material Failure of Atherosclerotic Lesions , Lindsey A. Davis

Enabling Studies to Optimize Biomaterials for the Treatment of Myocardial Infarction , Eva Adriana Romito

Theses/Dissertations from 2015 2015

Effects of Cell Adhesion Peptides, pH, and Matrix Shape on Maintenance of Breast Cancer Stem Cells in an Engineered Hydrogel Matrix , Leily Daneshian

Design and Development of a Ventilation Chamber for Testing Efficacy of Tracheal Stents , Caroline N. Horton

Material Considerations for Development of 3D Printed Bronchial and Tracheal Stents , Nidah M. Hussain

Theses/Dissertations from 2014 2014

Isolation of Natural Nrf2 Activators from American Ginseng , Akrm Abdalrahman

Genes Mediating Cardiac Remodeling During Pregnancy and the Early Post-Partum-Period in Mice , Esam Aljrbi

A Three-Dimensional in Vitromodel of Atherogenesis , Pin Hsuan Chang

Identifying Performance Criteria of Fully Bioresorbable Scaffolds for Endovascular Applications , Jahid Ferdous

Novel Conditioning Protocols Focusing on Oxygen Manipulation to Enhance Stem Cell Transplantation , Brandon William Hanna

Developing a Bioreactor for Biaxial Mechanical Testing and Conditioning of Vascular Tissue , Steve Marcous

Experimental and Theoretical Studies of Native and Engineered Vascular Tissue Mechanics , Boran Zhou

Theses/Dissertations from 2013 2013

Toward Directing Cell Fate: Carbon Nanotubes As Modulators of Extracellular and Transporters of Intracellular Cues , Qingsu Cheng

Biomechanics of Porcine Renal Artery and the Development of A Replacment Vessel , Mohamed Gabr

Osteon-Mimetic Nanocomposite Materials For Bone Regeneration , Ozan Karaman

Microencapsulation of a Connexin-43 Mimetic Peptide as a Novel Wound Healing Agent in an Ocular Injury Model , Keith Brian Moore

Gold Nanoparticles and Peptoids as Novel Inhibitors of Amyloid Beta Aggregation in Alzheimer's Disease , Kelly Ann Moore

Effect of Physiological Oxygen Levels On Osteogenic Differentiation of Adipose-Derived Stem Cells , Suchit Sahai

Investigation of START Domain Proteins in Human Luteinized Cells and COS-1 Cells , Bo Shi

Characterizing Hypoxia and Its Behavioral Effects In 3-Dimensional Cell Aggregates , Matthew Lorincz Skiles

The Effect of αCT-1 Peptide on Bone Marrow Stromal Cells Following Injury , Adam Clay Vandergriff

Theses/Dissertations from 2012 2012

Flow-Induced Forces Regulate the Development of Cardiac Valves , Stefanie Vawn Biechler

Stimulated Emission Depletion (STED) Microscopy and Pacific Orange Dye Optimization For H9C2 Cox-1 Imaging Via Indirect Immunocytochemistry , John Wesley Merriman

Vasculogenic Scaffolds: How Cell-Cell and Cell-Matrix Interactions Regulate Vascular Differentiation and Morphogenesis , Samantha Jo Stinson

A Novel Quantitative Mechanical Test of Atherosclerotic Plaque Stability , Ying Wang

Theses/Dissertations from 2011 2011

Synthesis and Characterization of Thermally Responsive Nanocapsules Surface Decorated With Folic Acid For Targeted Drug Delivery and Cancer Destruction , Kyle Bradley Gilstrap

Study of Polyphenols and Naphthalimide Analogs As Inhibitors of Amyloid- β Protein Aggregation In Alzheimer'S Disease , Chen Suo

Development and Characterization of Micro/Nano Scale Biomaterials For Biomedical Applications , WUJIE ZHANG

Theses/Dissertations from 2010 2010

Study of Structural and Physical Properties of Small Molecule and Nanoparticle Inhibitors of Amyloid-B Protein Fibril Formation In Alzheimer'S Disease , Deborah Soto-Ortega

Theses/Dissertations from 2009 2009

A Novel Technique for Fabricating Aligned Nanofibers by Using Solution Electrospinning , Ozan Karaman

Synthesis and Characterization of Injectable Star-shaped Poly(Lactide-co-Glycolide-co-Acrylate) Macromers , Jianping Wu

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Biomedical Science

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Please note :

• TU Dublin use the word "dissertation" for work done as part of an undergraduate or taught master's course, and the word  "thesis" for work done for PhD or research masters degrees
• Dissertations and theses completed before 2019 were submitted to DIT, which preceded TU Dublin, and these are listed as Dublin Institute of Technology works .

Final Year Dissertations

Dissertations for a number of science undergraduate and taught postgraduate programs are available to view in pdf  format from 2014 onwards. To view the outline,  layout, citation style and referencing quality of a science eDissertation follow the steps below:

Start at the TU Dublin Library Catalogue

• From the drop-down search menu choose Subject or  Title Search
• Input your program code e.g. TU852. You can use either a current TU Dublin program code or an older DIT code.
• Select the e Dissertations option.
• Click on the blue dissertations link and view or download the pdf as required. 

 Tip: Sort by Reverse Year to view the newer titles.  

Research Theses

Arrow@TUDublin is the institutional repository for the university and is where researchers and staff  make a version of their theses and published articles or book chapters freely available. All material on Arrow is full text. The theses collection for MPhils and PhDs is also available on Arrow.

• Open Access Theses and Dissertations (OATD)  provides online access to graduate theses and dissertations from over 1100 colleges, universities, and research institutions from around the world.
• The  DART-Europe E-Theses Portal provides access to over 1.6 million open access research theses from 572 Universities in 29 European countries.
• The British Library EThOS theses online service  offers a search option to over 500,000 doctoral theses. Download instantly for your research, or order a scanned copy quickly and easily.

A selection of research theses is also available for use in TU Dublin Library.  A listing of hardcopy PhD theses is available here.  Please note that print theses are for use in the library only.

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Biomedical Sciences Theses and Dissertations

If you are a graduate student submitting your thesis or dissertation, please click here to access the submission form.

Theses/Dissertations from 2023 2023

Intestinal Microbiome, Fecal Fermentation Profile, and Health Indices in HIV Infected Men versus Non-Infected Controls , Mary Andreae and Mary C. Andreae Mrs

Microsporidian Spores and the Integrin Binding Loop of the MADAM Protein Are Important for Integrin Signaling and Attachment to Host Cells , Cindy L. Barrett

Elucidation of the Role of Avocado WRI1 and WRI2 and Their Ability to Affect Oil Content and Composition When Co-expressed With PDAT1 and DGAT1 , Jyoti Ranjan Behera

Flavonol Glucosylation: A Structural Investigation of the Flavonol Specific 3-O Glucosyltransferase Cp3GT , Aaron S. Birchfield

Effect of Macrophage Expressed α7 Nicotinic Acetylcholine Receptor (α7nAChR) on Migration of Macrophages During Inflammation , Kasey Keever

MET Alterations in Glioblastoma: Characterization of Patient-Derived Xenografts and Therapeutic Strategies , Anna Musket

Investigating the Role of Maternal Adiposity on Human Breast Milk and Preterm Infant Stool Short Chain Fatty Acid and Microbiome Profiles , Kristy L. Thomas

Theses/Dissertations from 2022 2022

Importance of the Microhabitat and Microclimate Conditions in the Northern Gray-cheeked Salamander (Plethodon montanus) Across an Elevation Gradient , Trevor Chapman

A Functional Study of Topological DNA Problem in Human T cells During Chronic Viral Infection , Xindi Dang

Knockdown of C. elegans NAD Kinases NADK-1 or NADK-2 Induces an Antioxidant Response Without Affecting Lifespan , Henry Gong

Investigating the PI3K/AKT/ATM Pathway, Telomeric DNA Damage, T Cell Death, and CRISPR/Cas9-mediated Gene Editing During Acute and Chronic HIV Infection , Sushant Khanal

Validation of the 40 Hz Auditory Steady State Response as a Pharmacodynamic Biomarker of Evoked Neural Synchrony , Muhammad Ummear Raza

The Mechanisms of Mitochondrial Dysfunction in T Cell Aging during Chronic Viral Infection , Madison B. Schank

Theses/Dissertations from 2021 2021

GABAergic-Related Pathology in the Anterior Cingulate Cortex of Postmortem Human Brain Tissue in Autism Spectrum Disorder , Gethien Andrew

Endothelial Heat Shock Protein A12B and Yes-associated Protein Cooperatively Promote Angiogenesis Following Myocardial Infarction , Min Fan

Trained Immunity Enhances the Immune Response and Maintains Microbiome Diversity in Aging and Sepsis , P. Spencer Gill

Genital Chlamydia Infection is Influenced by the Female Sex Hormones Estrogen and Progesterone in Vivo , Amy Gail Gravitte

Role of Ataxia Telangiectasia Mutated Kinase in Western-type Diet-induced Cardiac Outcomes under Basal and Ischemic Conditions , Mary Wingard

Theses/Dissertations from 2020 2020

Development, Expansion and Role of Myeloid-Derived Suppressor Cells in Post-Sepsis Immune Suppression , Tuqa Alkhateeb

Axonal Regrowth of Olfactory Sensory Neurons After Chemical Ablation and Removal of Axonal Debris by Microglia , Rudy Chapman

Prevention of Chronic Inflammation by Targeting Macrophage Integrin aDb2 , Cady Forgey

Behavioral and Neurobiological Evidence of Epigenetic Transmission in the Neonatal Quinpirole Rodent Model of Schizophrenia , Wesley Gill

Understanding the Implications of Anandamide, an Endocannabinoid in an Early Land Plant, Physcomitrella patens , Md Imdadul Haq

Immune Activation Induces Telomeric DNA Damage, Reduces Memory Precursors, and Promotes Short-lived Effector T Cell Differentiation in Chronic HCV Infection , Lam Nguyen

A Novel Mode of Action of C-reactive Protein in Protecting Against Streptococcus pneumoniae Infection and Synergy with Antibiotics , Donald Ngwa

Chronic Effects of Methylphenidate on Neuronal Viability and Plasticity , Hannah Oakes

Protection Against Atherosclerosis by A Non-native Pentameric CRP that Shares its Ligand Recognition Functions with an Evolutionarily Distant CRP , Asmita Pathak

Roles of Endothelial Cell Heat Shock Protein A12B and β-glucan, a reagent for trained Immunity in the Regulation of Inflammation in Sepsis , Fei Tu

Theses/Dissertations from 2019 2019

Exploration of Ataxia Telangiectasia and Rad3-Related’s (ATR’s) Role in Cell Death Regulation: Implications in Development, Cancer, and Stroke , Brian Cartwright

The Distinct Expressions of Integrins αDβ2 and αMβ2 Differently Regulate Macrophage Migration in 3D Matrix in vitro and in Tissue during Inflammation , Kui Cui

Role of ATM in T Cell Dysfunction During Chronic Viral Infections , Juan Zhao

Theses/Dissertations from 2018 2018

The Combined Neuropharmacology and Toxicology of Major 'Bath Salts' Constituents MDPV, Mephedrone, and Methylone , Serena Allen

The Effect of Alcohol Consumption on Adipokine Secretion , Ashley DeGroat

Quantitative Studies of Amyloidogenic Protein Residue Interaction Networks and Abnormal Ammonia Metabolism in Neurotoxicity and Disease , Jeddidiah Griffin

Metabolic Plasticity in the Cellular Stress Response , Ying Li

HIV Integrase Inhibitor Pharmacogenetics and Clinical Outcomes: An Exploratory Association Study , Derek E. Murrell

Effects of Gender, Age, and Nutrition on Circadian Locomotor Activity Rhythms in the Flesh Fly Sarcophaga crassipalpis , Fritz Prohaska

Characterization of Acyltransferases and WRINKLED Orthologs Involved in TAG Biosynthesis in Avocado , Md Mahbubur Rahman

Virulence Regulation in Pseudomonas aeruginosa via the Alginate Regulators, AlgU and AlgR, the posttranscriptional regulator, RsmA, and the Two-component System, AlgZ/R , Sean Stacey

SIP-428, a SIR2 Deacetylase Enzyme and Its Role in Biotic Stress Signaling Pathway , Bal Krishna Chand Thakuri

Role of Ataxia-Telangiectasia Mutated Kinase in Cardiac Autophagy and Glucose Metabolism Under Ischemic Conditions , Patsy Thrasher

Investigating the Interaction of Monoamines and Diel Rhythmicity on Anti-Predator Behavior in an Orb-Weaving Spider, Larinioides cornutus (Araneae: Araneae) , Rebecca Wilson

Theses/Dissertations from 2017 2017

Role of Cannabinoid Receptor Type 2 (CB2) in Late Stage Atherosclerosis , Makenzie Fulmer

A-type Lamins in Cell Cycle Regulation , Jaime L. Parman-Ryans

Exogenous Ubiquitin: Role in Myocardial Inflammation and Remodeling Post- Ischemia/Reperfusion Injury , Stephanie Scofield

Role of TLRs, Hippo-YAP1 Signaling, and microRNAs in Cardiac Repair and Regeneration of Damaged myocardium During Ischemic Injury , Xiaohui Wang

Theses/Dissertations from 2016 2016

An Investigation into Formulation and Therapeutic Effectiveness of Nanoparticle Drug Delivery for Select Pharmaceutical Agents , Dustin Cooper

Strategies of Balancing: Regulation of Posture as a Complex Phenomenon , Allison Leich Hilbun

Investigation of Novel Functions for DNA Damage Response and Repair Proteins in Escherichia coli and Humans , Benjamin A. Hilton

Exploring the Relationship Between Behaviour and Neurochemistry in the Polyphenic Spider, Anelosimus studiosus (Araneae: Theridiidae) , Jennifer B. Price

In Vitro and In Vivo Characterization of Chlamydia and HSV Co-infection , Jessica A. Slade

A novel role of human DNA damage checkpoint protein ATR in suppressing Ca2+ overload-induced PARP1-mediated necrosis , Hui Wang-Heaton

Pharmacokinetics, Tissue Distribution, Synergistic Activity, and Antitumor Activity of Two Isomeric Flavones , Crystal L. Whitted

Regulation of Acute and Chronic Immune Responses by β-Arrestin2 , Hui Yan

Endothelial HSPA12B is a Novel Protein for the Preservation of Cardiovascular Function in Polymicrobial Sepsis via Exosome MiR-126 , Xia Zhang

Theses/Dissertations from 2015 2015

Role of Ataxia Telangiectasia Mutated Kinase in the Healing Process of the Heart Following Myocardial Infarction , Laura L. Daniel

Theses/Dissertations from 2014 2014

Cellular-based Brain Pathology in the Anterior Cingulate Cortex of Males with Autism Spectrum Disorder , Jessica D. Crawford

Extracellular Ubiquitin: Role in Cardiac Myocyte Apoptosis and Myocardial Remodeling , Christopher Ray Daniels

Novel Therapeutic Approaches for Ischemic Heart and Brain Injury: Modulation of Toll-Like Receptor-Mediated Signaling Pathways and PI3K/Akt Signaling , Chen Lu

Regulation of C-reactive Protein Gene Expression and Function , Avinash N. Thirumalai

A Comprehensive Study of the Effects of Neurotoxins on Noradrenergic Phenotypes, Neuronal Responses and Potential Intervention by Antidepressants in Noradrenergic Cells , Yan Wang

HIF-1α in the Heart: Provision of Ischemic Cardioprotection and Remodeling of Nucleotide Metabolism , Joe Wu

Theses/Dissertations from 2013 2013

An Examination of the Inhibitory Effects of Antibiotic Combinations on Ribosome Biosynthesis in Staphylococcus aureus , Justin Beach

Genetic Imbalances in Endometriosis Detected by Oligonucleotide-Array Based Comparative Genomic Hybridization , Natalie Burke

Arrested and Aberrant: Effects of Amoxicillin in a Murine Model of Chlamydial Infection , Regenia Beth Phillips Campbell

Identification and Characterization of Genetic Factors Involved in Candida-Bacterial Interactions , Sean J. Fox

Mechanisms of the Anti-Pneumococcal Function of C-Reactive Protein , Toh B. Gang

Microsporidia Spore Adherence and Host Cell Infection In Vitro , Cory A. Leonard

New Insights into the Roles of Human DNA Damage Checkpoint Protein ATR in the Regulation of Nucleotide Excision Repair and DNA Damage-Induced Cell Death , Zhengke Li

Novel Ester Substrates for the Detection and Treatment of Prostate Cancer , Christopher Allen McGoldrick

Novel Roles of Replication Protein A Phosphorylation in Cellular Response to DNA Damage , Moises A. Serrano

Bioengineering the Expression of Active Recombinant Human Cathepsin G, Enteropeptidase, Neutrophil Elastase, and C-Reactive Protein in Yeast , Eliot T. Smith

Theses/Dissertations from 2012 2012

Prelamin A Influences a Program of Gene Expression In Regulation of Cell Cycle Control , Christina N. Bridges

Detection and Purification of a Novel Natural Inhibitory Compound from an Isolated Strain of Rhodococcus Using an Agar Extraction Method , Megan Carr

An Investigation of Bacterial Ribonucleases as an Antibiotic Target , Ashley Denise Frazier

Stabilization of the Cardiac Nervous System During Cardiac Stress Induces Cardioprotection , David D. Gibbons

The Effects of Nicotine Administration on Behavior and Markers of Brain Plasticity in a Rodent Model of Psychosis , Marla K. Perna

Effects of Burn Injury on Biological Ethanol and Ethyl Glucuronide Concentrations , Trista Haupt Wright

Theses/Dissertations from 2011 2011

Role of Type 2 Cannabinoid Receptor (CB2) in Atherosclerosis. , Courtney Denise Netherland

Biopharmaceutic and Pharmacokinetic Studies of Sucrose Acetate Isobutyrate as an Excipient for Oral Drug Delivery. , Martin Ray Tant

Theses/Dissertations from 2010 2010

The Effect of Sternocleidomastoid Muscle Activation Pattern and Feedback Condition on the Vestibular Evoked Myogenic Potential. , Mary Jo Davenport

Mosaic Analysis with Double Markers (MADM) as a Method to Map Cell Fates in Adult Mouse Taste Buds. , Preston D. Moore

The Multifaceted Contribution of Natural Killer Cells During Herpes Simplex Type-1 Viral Infection. , Stacie N. Woolard

Theses/Dissertations from 2009 2009

Determining Putative Secondary Product Glucosyltransferase Expression During Citrus paradisi Growth and Development. , Jala Daniel

Dopamine D2 Receptor Priming Enhances Dopaminergic Response to Amphetamine in the Nucleus Accumbens: Role of the D1 and D2 Receptors. , Kimberly Norris Huggins

Localization of Calbindin-D 28k in Extra-Embryonic Membranes of Two Oviparous Scincid Lizards. , Shuo Li

Nectin-1 is Degraded in Chlamydia trachomatis -Infected Genital Epithelial Cells and is Required for Herpes Simplex Virus Co-Infection-Induced C. trachomatis Persistence. , Jingru Sun

Theses/Dissertations from 2008 2008

Elucidating the Role of the α7 Nicotinic Receptor in the Etiology of Schizophrenia. , Michelle Johnson Chandley

Identification of Chlamydial Iron-Responsive Proteins during Intracellular Growth. , Brian D. Dill

Antigen Trafficking within Chlamydia trachomatis -Infected Polarized Human Endometrial Epithelial Cells. , David Kelley Giles

Urinary Excretion of (1-3)-Beta-D-Glucans. , Debra K. Head

Expression, Purification, and Characterization of the Mast Cell Proteases Chymase and Cathepsin G. , Brent E. Lockhart

Characterization of Murine Cardiac Cholinergic Innervation and Its Remodeling in Type 1 Diabetes. , Abigail Marie Mabe

Structural and Biochemical Investigation of the Molecular Mechanisms of DNA Response and Repair in Humans and Escherichia coli . , Steven Michael Shell

Characterization of Heat Shock Protein A12B as a Novel Angiogenesis Regulator. , Rebecca J. Steagall

Herpes Simplex Virus Glycoprotein D/Host Cell Surface Interaction Stimulates Chlamydia trachomatis Persistence via a Novel Pathway. , Jennifer Vanover

Theses/Dissertations from 2007 2007

Characterization of a 30S Ribsomal Subunit Intermediate Found in Escherichia coli Cells Growing with Neomycin and Paromomycin. , Cerrone Renee Foster

Localization of a Microsporidia ADAM (A Disintegrin and Metalloprotease Domain) Protein and Identification of Potential Binding Partners. , Carrie E. Jolly

T-cell Dysfunction by HCV Core Protein Involves PD-1/PD-L1 Signaling. , Billy Ellis King

1, Structural and Functional Studies of Human Replication Protein A; 2 DNA Damage Responses and DNA Repair Defects in Laminopathy-Based Premature Aging. , Yiyong Liu

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Biomedical Engineering Theses and Dissertations

This collection contains theses and dissertations from the Department of Biomedical Engineering, collected from the Scholarship@Western Electronic Thesis and Dissertation Repository

Theses/Dissertations from 2024 2024

Co-delivery of Adipose-derived Stromal Cells and Endothelial Colony Forming Cells in Novel Cell-assembled Scaffolds as a Pro-angiogenic Cell Therapy Platform , Sarah A. From

Theses/Dissertations from 2023 2023

Multiparametric Classification of Tumor Treatment Using Ultrasound Microvascular Imaging , mahsa bataghva

Towards Patient Specific Mitral Valve Modelling via Dynamic 3D Transesophageal Echocardiography , Patrick Carnahan

Developing a Finite Element Model for Evaluating the Posterior Tibial Slope in a Medial Opening Wedge High Tibial Osteotomy , VIctor Alexander Carranza

Analysis and Characterization of Embroidered Textile Strain Sensors for Use in Wearable Mechatronic Devices , Jose Guillermo Colli Alfaro

Developing Bioactive Hydrogels Containing Cell-derived Extracellular Matrix for Bone and Cartilage Repair , Ali Coyle

Modelling of a TCA-driven Wearable Tremor Suppression Device for People with Parkinson’s Disease , Parisa Daemi

Using Machine Learning Models to Address Challenges in Lung Cancer Care , Salma Dammak

Longitudinal dynamics of cerebrospinal fluid Aꞵ, pTau and sTREM2 reveal predictive preclinical trajectories of Alzheimer’s pathology , Bahaaldin Helal

MAGNETIC RESONANCE IMAGING BIOMARKERS FOR PARKINSON’S DISEASE: A MACHINE LEARNING APPROACH , Dimuthu Henadeerage Don

Detecting Treatment Failure in Rheumatoid Arthritis with Time-Domain Diffuse Optical Methods , Seva Ioussoufovitch

Novel Magnetic Resonance Imaging-Compatible Mechatronic Needle Guidance System for Prostate Focal Laser Ablation Therapy , Eric R. Knull

The Development of Stimuli-responsive Hydrogels from Self-Immolative Polymers , Jared David Pardy

Free-hand Photoacoustic Imaging of Breast Cancer Tissue , Elina Rascevska

Development of a Cell-based Regenerative Strategy to Modulate Angiogenesis and Inflammation in Ischemic Muscle , Fiona E. Serack

Investigation of Dynamic Culture on Matrix-derived Microcarriers as a Strategy to Modulate the Pro-Regenerative Phenotype of Human Adipose-derived Stromal Cells , McKenna R. Tosh

Evaluating EEG–EMG Fusion-Based Classification as a Method for Improving Control of Wearable Robotic Devices for Upper-Limb Rehabilitation , Jacob G. Tryon

Theses/Dissertations from 2022 2022

A two-layer continuous-capillary oxygen transport model: Development and application to blood flow regulation in resting skeletal muscle. , Keith C. Afas

Development of a Hybrid Stereotactic Guidance System For Percutaneous Liver Tumour Ablation , Joeana N. Cambranis Romero

Large-scale Analysis and Automated Detection of Trunnion Corrosion on Hip Arthroplasty Devices , Anastasia M. Codirenzi

The Role of Transient Vibration of the Skull on Concussion , Rodrigo Dalvit Carvalho da Silva

Biomechanical Investigation of Complete and Partial Medial Collateral Ligament Injuries , Callahan Doughty

Towards A Comprehensive Software Suite for Stereotactic Neurosurgery , Greydon Gilmore

The Bio-Mechanical Development and Kinematic Evaluation of Zone I and Zone II Injuries and their Corresponding Surgical Repair Techniques using an In-Vitro Active Finger Motion Simulator: A Cadaveric Study , Mohammad Haddara

Image-based Cochlear Implant Frequency-to-Place Mapping , Luke William Helpard

Mechanical Evaluation of Gyroid Structures to Combat Orthopaedic Implant Infections , Sydney Hitchon

The Development of a Motion Sensing Device for Use in a Home Setting , Jaspreet K. Kalsi

A Novel Ultrasound Elastography Technique for Evaluating Tumor Response to Neoadjuvant Chemotherapy in Patients with Locally Advanced Breast Cancer , Niusha Kheirkhah

Thermo-responsive Antibiotic-Eluting Coatings for Treating Infection near Orthopedic Implants , Jan Chung Kwan

Effects of Modulating the Culture Microenvironment on the Growth and Secretome of Human Adipose-Derived Stromal Cells , Zhiyu Liang

Conducting Polypyrrole Hydrogel Biomaterials For Drug Delivery And Cartilage Tissue Regeneration , Iryna Liubchak

Motion and Crosslinked Polyethylene Wear in Reverse Total Shoulder Arthroplasty , Christopher Millward

Intracardiac Ultrasound Guided Systems for Transcatheter Cardiac Interventions , Hareem Nisar

Investigation of Cell Derived Nanoparticles for Drug Delivery and Osteogenic Differentiation of Human Stem/Stromal Cells , Shruthi Polla Ravi

Quantitative Image Analysis of White Matter Dysregulation Using Brain Normalization for Diagnostic Analysis of Pediatric Hydrocephalus , Renee-Marie Ragguett

Automation through Deep-Learning to Quantify Ventilation Defects in Lungs from High-Resolution Isotropic Hyperpolarized 129Xe Magnetic Resonance Imaging , Tuneesh Kaur Ranota

Early Biological Response of Articular Cartilage to Hemiarthroplasty Wear , Debora Rossetti

Sol-Gel Derived Bioceramic Poly(Diethyl Fumarate – Co – Triethoxyvinylsilane) Composite , Aref Sleiman

The Application of Digital Volume Correlation Bone Strain Measurements in the Osteoarthritic Glenohumeral Joint , Jakub R. Targosinski

Development of Brain-Derived Bioscaffolds for Neural Progenitor Cell Culture and Delivery , Julia Terek

Modelling and Evaluation of Piezoelectric Actuators for Wearable Neck Rehabilitation Devices , Shaemus D. Tracey

Development of a Combined Experimental-Computational Framework to Study Human Knee Biomechanics , Samira Vakili

Investigation on the Performance of Dry Powder Inhalation System for Enhanced Delivery of Levosalbutamol Sulfate , Yuqing Ye

Theses/Dissertations from 2021 2021

Development of a Wireless Telemetry Load and Displacement Sensor for Orthopaedic Applications , William Anderson

Organic-Inorganic Hybrid Biomaterials for Bone Tissue Engineering and Drug Delivery , Neda Aslankoohi

Fabrication Of Inkjet-Printed Enzyme-Based Biosensors Towards Point-Of-Care Applications , Yang Bai

The Use of CT to Assess Shoulder Kinematics and Measure Glenohumeral Arthrokinematics , Baraa Daher

The Development of Region-Specific Decellularized Meniscus Bioinks for 3D Bioprinting Applications , Sheradan Doherty

In Vitro Analyses of the Contributions of the Hip Capsule to Joint Biomechanics , Emma Donnelly

Long-Circulating, Degradable Lanthanide-Based Contrast Agents for Pre-Clinical Microcomputed Tomography of the Vasculature , Eric Grolman

Mixed-reality visualization environments to facilitate ultrasound-guided vascular access , Leah Groves

Diffusion Kurtosis Imaging in Temporal Lobe Epilepsy , Loxlan W. Kasa

Extracellular Matrix-Derived Microcarriers as 3-D Cell Culture Platforms , Anna Kornmuller

3D Printed Polypyrrole Scaffolds for pH Dependent Drug Delivery with Applications in Bone Regeneration , Matthew T. Lawrence

Development of Multifunctional Drug Delivery Systems for Locoregional Therapy , Xinyi Li

Motion Intention Estimation using sEMG-ACC Sensor Fusion , Jose Alejandro Lopez

Biomaterial for Cervical Intervertebral Disc Prosthesis , Helium Mak

Biomechanical Analysis of Ligament Modelling Techniques and Femoral Component Malrotation Following TKA , Liam A. Montgomery

Snapshot Three-Dimensional Surface Imaging With Multispectral Fringe Projection Profilometry , Parsa Omidi

4DCT to Examine Carpal Motion , Sydney M. Robinson

Seizure Detection Using Deep Learning, Information Theoretic Measures and Factor Graphs , Bahareh Salafian

Modeling Fetal Brain Development: A semi-automated platform for localization, reconstruction, and segmentation of the fetal brain on MRI , Jianan Wang

Immobilized Jagged1 for Notch3-specific Differentiation and Phenotype Control of Vascular Smooth Muscle Cells , Kathleen E. Zohorsky

Theses/Dissertations from 2020 2020

Simulation Approaches to X-ray C-Arm-based Interventions , Daniel R. Allen

Implementing a multi-segment foot model in a clinical setting to measure inter-segmental joint motions , Tahereh Amiri

Cardiac Modelling Techniques to Predict Future Heart Function and New Biomarkers in Acute Myocardial Infarction , Sergio C. H. Dempsey

Feasibility of Twisted Coiled Polymer Actuators for Use in Upper Limb Wearable Rehabilitation Devices , Brandon P.R. Edmonds

Metal Additive Manufacturing for Fixed Dental Prostheses , Mai EL Najjar

Using an Internal Auditory Stimulus to Activate the Developing Primary Auditory Cortex: A Fetal fMRI Study , Estee Goldberg

Development of Water-Soluble Polyesters for Tissue Engineering Applications , Trent Gordon

Development Of Hybrid Coating Materials To Improve The Success Of Titanium Implants , Zach Gouveia

A 3D Printed Axon-Mimetic Diffusion MRI Phantom , Tristan K. Kuehn

Development of an Active Infection Monitoring Knee Spacer for Two-Stage Revision , Michael K. Lavdas

Computational Modeling of the Human Brain for mTBI Prediction and Diagnosis , Yanir Levy

Pulmonary Imaging of Chronic Obstructive Pulmonary Disease using Multi-Parametric Response Maps , Jonathan MacNeil

Optimization of Indentation for the Material Characterization of Soft PVA-Cryogels , Md. Mansur ul Mulk

Development and Validation of Augmented Reality Training Simulator for Ultrasound Guided Percutaneous Renal Access , Yanyu Mu

A Biomechanical Investigation into the Effect of Experimental Design on Wrist Biomechanics and Contact Mechanics , Clare E. Padmore

Structure-Function Relationships in the Brain: Applications in Neurosurgery , Daiana-Roxana Pur

The Effect of Joint Alignment After a Wrist Injury on Joint Mechanics and Osteoarthritis Development , Puneet Kaur Ranota

Development and Validation of Tools for Improving Intraoperative Implant Assessment with Ultrasound during Gynaecological Brachytherapy , Jessica Robin Rodgers

Studies on Carbon Quantum Dots with Special Luminescent Properties and Their Capability of Overcoming the Biological Barriers , Ji Su Song

Machine Learning towards General Medical Image Segmentation , Clara Tam

The Migration and Wear of Reverse Total Shoulder Arthroplasty , Madeleine L. Van de Kleut

Video Processing for the Evaluation of Vascular Dynamics in Neurovascular Interventions , Reid Vassallo

Preparation of Intra-articular Drug Delivery Systems for the Treatment of Osteoarthritis , Ian Villamagna

Deep Reinforcement Learning in Medical Object Detection and Segmentation , Dong Zhang

Theses/Dissertations from 2019 2019

Fabrication and Characterization of Collagen-Polypyrrole Constructs Using Direct-Ink Write Additive Manufacturing , Rooshan Arshad

Development of a Force-Based Ream Vector Measurement System For Glenoid Reaming Simulation , David Axford

Investigation of Visual Perceptions in Parkinson's Disease and the Development of Disease Monitoring Software , Matthew Bernardinis

Tissue Equivalent Gellan Gum Gel Materials for Clinical MRI and Radiation Dosimetry , Pawel Brzozowski

Implementation of User-Independent Hand Gesture Recognition Classification Models Using IMU and EMG-based Sensor Fusion Techniques , José Guillermo Collí Alfaro

Scaffold Design Considerations for Soft Tissue Regeneration , Madeleine M. Di Gregorio

Remote Navigation and Contact-Force Control of Radiofrequency Ablation Catheters , Daniel Gelman

High-throughput Fabrication of Drug-loaded Core-shell Tablets with Adjustable Release Profiles from Surface-erodible and Photocrosslinkable Polyanhydrides , Armin Geraili Nejadfomeshi

Apply dry powder on drug loading and enteric coating of esomeprazole magnesium trihydrate beads and capsules , Xiaojing Ge

Bioluminescence resonance energy transfer (BRET) - based nanostructured biosensor for detection of glucose , Eugene Hwang

A Heterogeneous Patient-Specific Biomechanical Model of the Lung for Tumor Motion Compensation and Effective Lung Radiation Therapy Planning , Parya Jafari

The Co-Delivery of Syngeneic Adipose-Derived Stromal Cells and Macrophages on Decellularized Adipose Tissue Bioscaffolds for In Vivo Soft Tissue Regeneration , Hisham A. Kamoun

Improving Material Mapping in Glenohumeral Finite Element Models: A Multi-Level Evaluation , Nikolas K. Knowles

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Science Dissertation Topics

Published by Carmen Troy at January 9th, 2023 , Revised On October 5, 2023

Introduction

The exact pinnacle point of the academic life of a science student is to test their understanding of the science by identifying a real-life science problem and then figuring out the solution through res

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2022 Science Research Topics

Topic 1: how do our genes influence our lifestyle and behavior.

Research Aim: Inherited genetic predispositions largely determine individual differences in intellectual ability, personality, and mental health. Behavior also displays indicators of genetic influence; for example, how somebody reacts to stressful circumstances reflects some genetic influence. This research aims to find the impact of genes on a person’s lifestyle and behavior. The study will also examine the ratio of people likely to be affected by genetics.

Topic 2: What effect do schools have on childhood obesity? The case in the UK schools.

Research Aim: Over the last few years, the world has seen a dramatic rise in the frequency of childhood obesity. When the children finish elementary school, one-third of youngsters in the UK are overweight or obese. The research will aim to identify the problems that cause obesity in children in UK schools. It will also explain how obesity causes other health issues in children. The research will also give strategies and frameworks to reduce the obesity rate in children in schools.

Topic 3: The role of biotechnology in developing more effective vaccines.

Research Aim: The research will aim to identify the role of biotechnology in developing more effective vaccines. Vaccination is amongst the most effective methods of combating infectious diseases. It was solely accountable for eradicating chickenpox and controlling yellow fever, polio, and Rubella in humans and exotic Newcastle disease, FMD, and fowl paralysis in poultry. The research will also explain how biotechnology has helped scientists eradicate diseases worldwide.

Topic 4: How is public transportation better for the atmosphere than private transport?

Research Aim: The research will aim to find the benefits of public transportation and why it is better than private transportation for the environment. The current amount of automobile transport globally is becoming a social, environmental, and economic issue. The research will also examine the influence of private transportation on the environment and health of the public. It will also explain the strategies to reduce the use of personal vehicles and how public transport can be improved.

Topic 5: Will nanotechnology in genome research contribute to the development of health standards?

Research Aim: The research will aim to investigate the use of nanotechnology in genome research and how it will help develop health standards. Curiosity, amazement, and creativity are human attributes that have existed since the dawn of time. People worldwide have turned their intellectual curiosity into scientific investigation and technique. In recent years, there has been an incredible increase in research in the field of nanoscience. There is growing hope that nanotechnology applied to medicine and dentistry may lead to substantial disease detection, treatment, and prevention advancements.

Covid-19 Pharmacology Research Topics

Topic 1: pharmacologic treatments of covid-19.

Research Aim: This study will focus on investigating the Pharmacologic treatments of COVID-19

Topic 2: The role of science and scientists during Coronavirus pandemic

Research Aim: This study will address the contributions of science and scientists during the COVID-19

Topic 3: The biology of the Coronavirus pandemic

Research Aim: This study will analyse the biology of the Coronavirus pandemic; its symptoms, risks, and preventive measures will be discussed.

Topic 4: The long-term effects of the Coronavirus pandemic on the field of science

Research Aim: This study will focus on predicting the long-term effects of Coronavirus pandemic on the field of science

Science Dissertation Topics 2021

Topic 1: epidemiology and coronavirus.

Research Aim: This research aims to focus on COVID-19 Epidemiology to get in-depth information about the disease.

Topic 2: Impacts of climate changes on agriculture

Research Aim:  This research aims to study the impacts of climate changes on agriculture, address the issues of the farmers, especially in Asian countries and suggest possible solutions solve them

Topic 3: A study on endangered species

Research Aim: This research aims to identify and gather information about endangered species, study their anatomy, and determine the reasons for their extinction.

Topic 4: Types of diets- a comparative study

Research Aim: This research aims to identify and compare the types of diets- a comparative study. Measure their effectiveness and provide an evidence-based conclusion to achieve a healthy lifestyle.

Topic 5: Hormonal imbalance - a comparative study

Research Aim: This research aims to address hormonal imbalance issues among teenage girls and women and conduct a comparative study to cover all important aspects of this topic.

Pharmacology Dissertation Topics

Topic 1: harnessing ion-binding sites for g-protein coupled receptors pharmacology (gpcr)..

Research Aim: In this research, the vital role of endogenous ions in the function and pharmacology of G-Protein Coupled Receptors (GPCR) will be observed. The theoretical synthesis and highlight or recent advancements in the functional, biophysical, and structural characterization of GPCR bounded ions will also be discussed.

Topic 2: Bisphosphonate Pharmacology

Research Aim: In this research, the biological effects of bisphosphonates as inhibitors for the processes of calcification and bone resorption as well as their later use for the treatment of skeletal disorders is discussed. Other potential purposes of bisphosphonate, such as its applications to treat cardiovascular diseases and radiation protection, are also considered.

Topic 3: Neurobiology and Molecular Pharmacology of Rapid-Acting Antidepressants.

Research Aim: This research will explain why the reconceptualisation of depression treatment soon. The clinical data of each rapid-action antidepressant will be compared as well as their mechanism of action. Additionally, the drug’s neurobiological circuits can be applied to the formation of later on medication.

Topic 4: System Pharmacology and Pharmacometrics in regards to metabolic bone disease.

Research Aim: This research will focus on the mathematical modelling and various simulations of drug concentrations, effects, and the physiological system in which they interact. This is useful for the preclinical, translational, and clinical development of the drug in question. This research will focus on medications for various metabolic bone diseases.

Topic 5: The Pharmacology of inhaled anaesthetics.

Research Aim: In this research, the effects of inhaled anesthesia will be discussed compared to general anesthesia. Its impact with low, average, and high doses in humans and animals will also be explained.

Topic 6: Pharmacology of cancer.

Research Aim: In this research, the molecular structure of various tumors is discussed along with the therapeutic issues faced for these ailments and their treatments. Target spots for treatment and different chemical mixes for its treatments are also explained in this research.

Public Health Dissertation Topics

Topic 1: to protect health through the important role of climate action..

Research Aim: In this research, the effects of climate change are explained as well as its adverse impacts on human health. Ways to control climate change and reverse its harmful effects are also discussed in this paper.

Topic 2: The effect of electronic health records on health care quality and utilisation.

Research Aim: In this research, the universal electronic health recording system is discussed. This research will examine the various factors that influence electronic health recordings, such as clinical care benefits, financial implications, and cost and time efficiency.

Topic 3: The assessment of health impacts in low and middle-income countries.

Research Aim: This research will focus on studying the shortcomings of health care and its impact on societies and individuals living in low and middle-income countries. The effort to overcome these shortcomings and long-term solutions for these countries is also discussed here.

Topic 4: Dementia care through community-based activity: Museum object handling.

Research Aim: This research will highlight the importance of health-promoting by studying the effect of handling museum objects by people with dementia at stages. The study will consider the stage of dementia faced along with gender, time, domain, and age.

Topic 5: Health and green space.

Research Aim: This research will observe the effects of green space or natural environment on humans’ mental and physical health. The impact of living in a natural setting and living in an urban area will also be compared in this paper. The effect of living in a green space on essential biological processes such as pregnancy will be discussed in detail.

Topic 12: Public health in association with the quality of drinking water.

Research Aim: This research will study the effect of the world’s varying water qualities and their impact on human health. This research will also include studying different water-borne diseases and how to restrict and prevent them.

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Veterinary Medicine Dissertation Topics

Topic 1: the use of cannabis in veterinary medicines..

Research Aim: This research will study the effects of cannabis treatment on animals. The impact of cannabis on animals will be compared to the effects felt on the human body. The way an animal’s body reacts to cannabis and its effect on various body systems will also be observed.

Topic 2: Cardiomyopathies inheritance in veterinary medicines.

Research Aim: This research will aim to identify the effects of cardiomyopathy in animals in an attempt to seek a solution to this problem in humans. Veterinary medication is a mode in which it is easier to study this disease’s effects in animals of a single species. Using this method makes it easier to identify the areas of translational research and observe the future direction of this cardiovascular disease.

Topic 3: The potential use of amniotic stem cells in veterinary medications.

Research Aim: This research will observe the effect of using amniotic stem cells in veterinary medicines to curb some animal illnesses. The collection of these amniotic stem cells is done by collecting the discarded fetal membrane. The collection and separation of the stem cells from the fetal membrane are also explained.

Topic 4: The harm caused in veterinary hospitals due to medical errors.

Research Aim: This research will highlight the overall mortality rate of animals in three veterinary hospitals within a time span of three years. This figure is compared to the mortality rate of humans in the same time period. The reasons for the mortality of animals due to medical errors are also discussed, along with solutions.

Topic 5: Bulldog disorders in the UK in 2019 which are under primary veterinary care.

Research Aim: This research will take an in-depth study of the increased disorders observed in bulldogs in the UK in 2019 only. This research will cover all aspects of bulldog disorders, including age, weight, height and length, cause of mortality, diet, and veterinary plans. This research aims to highlight these factors to improve the health and wellbeing of this breed.

Topic 6: Controlling platyhelminth parasites in fish by using praziquantel.

Research Aim: This research will review the effect of praziquantel treatment on fish found to be infected with the platyhelminth parasite. The study will use captive fish since they are more susceptible to showing the parasite results than wild fish. This paper will also discuss the effect of this parasite if a human ingests an infected fish. The efficiency of the praziquantel and its toxicity information, assessments of administration routes, and pharmacokinetics are also reviewed.

Diseases and Pathogens Dissertation Topics

Topic 1: control of infectious diseases through precision epidemiology..

Research Aim: This research will explain the transmission mode of infectious diseases and how they spread. The process of precision epidemiology will also be explained. The use of precision epidemiology to treat infectious diseases by methods such as genome-based and individual level treatments is also discussed.

Topic 2: Reconstruction and prediction of viral epidemic diseases.

Research Aim: This research will provide a detailed study of the increase in viral epidemics globally. The re-occurrence of diseases once thought to be under control is also provided in this research. Methods to develop models for the prediction and the reconstruction of future epidemics are also discussed to help prevent such outbreaks.

Topic 3: Emerging pathogens and viral febrile illness.

Research Aim: This research will explain the exponential rise of newly emerging pathogens that the world is or will later face in a future epidemic. The study of new pathogens is carried out by the study of patients who contract a febrile illness. The complete research of the febrile virus from incubation to the human body is explored in this paper.

Topic 4: The Study of pathology and pathogenesis of Chagas heart disease.

Research Aim: This research will focus on the aspect of Chagas’s heart disease. The study will explain the mechanism — mode of transfer and the incubation period of the virus. The carrier of the virus in which it remains dormant is also studied along with its habitat and precautionary methods to avoid it.

IT in Biomedical Science Dissertation Topics

Topic 1: health care and medicine in the future..

Research Aim: This research will look at the development and effects of integrating information technology and biomedicine. All the advantages and disadvantages of introducing information technology into the biomedical sciences will be weighed together.

Topic 2: An introduction to Biomedical Informatics.

Research Aim: This research will focus on biomedical informatics’s complete detail. Since it does not have an adequately well-explained definition, the student will attempt to effectively explain the convergence of information technology and biomedicine.

Topic 3: Educating physicians through the use of Biomedical Informatics.

Research Aim: This research will look into the use of biomedical informatics for the education of young doctors and physicians. The study will examine the advantages of using biomedical informatics in physicians’ training and education compared to conventional methods.

Topic 4: The integration of Biomedical Informatics in clinical trials by new methods.

Research Aim: This research will discuss the advantages of implementing biomedical informatics in clinical trials. This includes the ease of data collection, interpretation, and analysis.

Topic 5: A review of the application of Biomedical Informatics in asthma care.

Research Aim: This research will highlight the unnecessary variation of patient care for asthma patients. A complete systematic view of the application of biomedical informatics in asthma patients’ care will also be discussed, along with its advantages and disadvantages in applying this system to asthma care.

Topic 6: The need for Biomedical Informatics for military research.

Research Aim: This research will explain the need for integrating biomedical informatics into military research. Biomedical informatics integration in military research will affect four focus areas: Health and Clinic Informatics, E-Health, Combat Health Informatics, and Bioinformatics and Biomedical Computation.

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Immunology and Biochemistry Dissertation Topics

Topic 1: the use of terrestrial habitat to heighten the immune system function of polar bears..

Research Aim: This research addresses climate change because a large number of polar bears are forced to spend the summertime on the shores. The immunity of bears on ice and those onshore will be compared to observe any changes in both bears’ immunity.

Topic 2: Inflammation and immune system regulation by Vitamin E.

Research Aim: This research aims to explain the role of vitamin E in regulating inflammation and the management of the immune system. Excess, moderate, and deficient amounts of vitamin E on the immune system and the region of inflammation are also described.

Topic 3: To Determine the responsiveness of antibodies towards vaccines by immune mechanisms.

Research Aim: This research will highlight the dangers of the lack of vaccine effectiveness and characterize the vaccines into groups of late and early response times. The antibodies’ response rates to their respective vaccines will be noted and compared to others’ response rates in the groups.

Topic 4: A relational study between immunology and food components.

Research Aim: This research will analyse the impact that different food components have on adults’ immune systems. The research looks to examine the characteristics of allergic reactions caused by food groups. The study will use patient data from emergency rooms in the UK.

Topic 5: The evolution to autoimmunity with reference to the Biochemistry of humans and viruses.

Research Aim: This research will compare and contrast the peptide binding of five disease-causing viruses in humans. The origin of the virulent materials and their individual effect on an adult body is discussed. The characteristic of autoimmunity is also explained by observing the immunity of humans over time.

Epidemiology Dissertation Topics

Topic 1: epidemiology of kidney diseases in the united states for the year 2018..

Research Aim: This research will analyze the data collected in the United States for 2018 in adults. The analysis will cover all the factors that cause renal diseases in adults of the US and categorize illnesses into different groups such as age, diet, obesity, hypertension, diabetes, and other conditions.

Topic 2: Epidemiology of Alzheimer’s disease in the UK.

Research Aim: This research will analyse the increasing and widespread age-associated dementia in the world’s elderly population. The analysis will cover the elderly populace of the UK over the past 3 years. The factors in the increase in the number of Alzheimer’s patients will also be discussed.

Topic 3: Epidemiology of invasive B Streptococcal infections among nonpregnant women in the UK.

Research Aim: This research will analyze the data collected from 2010 to 2018 concerning the incidents of B Streptococcus infections found in nonpregnant women of the United Kingdom. Factors that cause the rise in this infection are also discussed, and preventive measures for B Streptococcus infections.

Topic 4: Epidemiology of obesity and pathogenesis in the US.

Research Aim: This research will analyze the data collected via a survey of adults’ obesity rate in the United States from the past 5 years. The issue of obesity will be discussed along with the factors causing a rise in the obesity rate in the US. Prevention and cautionary measures to reduce the rate of obesity in adults are also discussed.

Important Notes:

As a science looking to get good grades, it is essential to develop new ideas and experiment on existing scientific theories – i.e., to add value and interest in the topic of your research.

The field of science is vast and interrelated to many other academic disciplines like  civil engineering ,  construction ,  law , and even  healthcare . That is why it is imperative to create a scientific dissertation topic that is articular, sound, and actually solves a practical problem that may be rampant in the field.

We can’t stress how important it is to develop a logical research topic; it is based on your entire research. There are several significant downfalls to getting your topic wrong; your supervisor may not be interested in working on it, the topic has no academic credit-ability, the research may not make logical sense, there is a possibility that the study is not viable.

This impacts your time and efforts in  writing your dissertation  as you may end up in the cycle of rejection at the initial stage of the dissertation. That is why we recommend reviewing existing research to develop a topic, taking advice from your supervisor, and even asking for help in this particular stage of your dissertation.

Keeping our advice in mind while developing a research topic will allow you to pick one of the best science dissertation topics that fulfill your requirement of writing a research paper and adds to the body of knowledge.

Therefore, it is recommended that when finalizing your dissertation topic, you read recently published literature to identify gaps in the research that you may help fill.

Remember- dissertation topics need to be unique, solve an identified problem, be logical, and be practically implemented. Please look at some of our sample scientific dissertation topics to get an idea for your dissertation.

How to Structure your Science Dissertation

A well-structured   dissertation can help students   to achieve a high overall academic grade.

• A Title Page
• Acknowledgments
• Declaration
• Abstract: A summary of the research completed
• Table of Contents
• Introduction : This chapter includes the project rationale, research background, key research aims and objectives, and the research problems. An outline of the structure of a dissertation can  also be added to this chapter.
• Literature Review :  This chapter presents relevant theories and frameworks by analyzing published and unpublished literature available on the chosen research topic to address  research questions . The purpose is to highlight and discuss the selected research area’s relative weaknesses and strengths while identifying any research gaps. Break down the topic and key terms that can positively impact your dissertation and your tutor.
• Methodology: The  data collection  and  analysis  methods and techniques employed by the researcher are presented in the Methodology chapter, which usually includes  research design, research philosophy, research limitations, code of conduct, ethical consideration, data collection methods, and  data analysis strategy .
• Findings and Analysis: Findings of the research are analyzed in detail under the Findings and Analysis chapter. All key findings/results are outlined in this chapter without interpreting the data or drawing any conclusions. It can be useful to include  graphs ,  charts, and  tables  in this chapter to identify meaningful trends and relationships.
• Discussion and  Conclusion:  The researcher presents his interpretation of the results in this chapter and states whether the research hypothesis has been verified or not. An essential aspect of this section is establishing the link between the results and evidence from the literature. Recommendations with regards to the implications of the findings and directions for the future may also be provided. Finally, a summary of the overall research, along with final judgments, opinions, and comments, must be included in the form of suggestions for improvement.
• References:  Make sure to complete this following your University’s requirements
• Bibliography
• Appendices: Any additional information, diagrams, and graphs used to  complete the dissertation  but not part of the dissertation should be included in the Appendices chapter. Essentially, the purpose is to expand the information/data.

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Our team of writers is highly qualified. They are experts in their respective fields. They have been working for us for a long time. Thus, they are well aware of the issues and the trends of the subject they specialize in. 

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Frequently Asked Questions

How to find dissertation topics about science.

For science dissertation topics:

• Follow latest scientific advancements.
• Investigate unresolved questions.
• Browse reputable journals.
• Explore interdisciplinary areas.
• Consult professors for guidance.
• Opt for topics aligning with your passion and career aspirations.

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74 Biomedicine Essay Topic Ideas & Examples

🏆 best biomedicine topic ideas & essay examples, 📝 interesting topics to write about biomedicine, 📌 simple & easy biomedicine essay titles.

• Advanced Biomedical Devices Case Analysis The success of the company in the United States suggests that the speedheals could hit the European market. According to the case, none of the competitors has achieved the level of innovation associated with the […]
• Choosing the Right Career Path: Biomedical and Civil Engineering Biomedical engineers join sound skills of engineering and biological science, and so tend to have a bachelor of science and superior degrees from major universities, who are now recovering their biomedical engineering program as interest […] We will write a custom essay specifically for you by our professional experts 808 writers online Learn More
• Female Bodies in Science and Biomedicine The assigned readings focus on the ways the female body is regarded in the context of biomedicine. In conclusion, it is necessary to note that gender is one of the constructs shaping the way people […]
• Cell Culture and Biomedical Applications This situation of cell line cross contamination could be attributed to constant necessity in the protocol for cell culture viability and identification.
• The Worth of Biomedical Ethics in Nursing Practice However, sometimes, the necessity of focusing on treatment and recovery makes healthcare providers unintentionally neglect or forget about the principles of autonomy, beneficence, nonmaleficence, and justice. In addition, following the rules of beneficence and nonmaleficence […]
• Behavioral and Biomedical Theories in Nursing Role categories like role ambiguity, role overload, and role conflict contribute to role stress. The change from nurse-to-nurse practitioner is an illustration of role ambiguity.
• Biomedical Technologies and Natural Family Planning Cervical mucus is a cervical secretion; tracking changes in CM is the easiest and most reliable way to predict the most fertile days.
• Biomedical Sciences in Nursing The concept of the web of causation has been formulated in the 1970s to solidify the idea of multidimensional causes of diseases and establish the model for explaining chronic conditions that are not fully attributable […]
• Biomedical Research Ethics and Human Rights This paper aims to discuss the impact of the history of research ethics on modern approaches and the protection of the rights of human subjects.
• Imaging Speed in Biomedical Engineering A substitute for this in achieve the high speed requirement involves the use of a video rate laser scanner which would have an added advantage of being able to control the size of the aperture […]
• Importance and Role of Biomedicine By studying a model of the natural history of the disease, the primary function is to identify the stages of prepathogenesis, pathogenesis, and prevention methods.
• Biomedical Theories and Models in Healthcare Delivery The genetic basis of cancer theory is one of these paradigms, and it focuses on the genesis of the disease. A combination of factors leads to the occurrence and proliferation of cancer cells.
• Principles of Ethics Among Biomedical Practitioners It shows a situation whereby medical professionals have to take care of people, who are not fully aware of the moral principles that govern them.
• The Analysis of the Results of the Biomedical Research The article is devoted to the analysis of the results of the biomedical research carried out in Lebanon and the United Arab Emirates.
• Health Care Disparity and Principles of Biomedical Ethics Healthcare disparities can be explained as the differences or the inequalities that exist in the provision of medical care to various groups of people. The most significant theories in the US have been the theory […]
• Nanotechnology and Bio-Electrospray: In the Context of Biomedical Applications In recent years one of the most promising applications is the use of electrospraying to manipulate cells and transport them without compromising the integrity of the cell. One can just imagine the extreme minuteness of […]
• Bioethical Position on Medical Futility Nursing Advocates for the withdrawal of treatment for severely deformed infants base their arguments on the fact that treatment for severely deformed infants is futile.
• Ethical Issues on Protection of Human Subjects in Biomedical Research First, ethical issues surrounding the protection of human subjects can be solved through assessing the risks and benefits of the medical experiment beforehand.
• Biomedical Informatics and Pharmacovigilance The analysis of the study makes it possible to assess the measures taken to enhance the role of biomedical informatics in healthcare.
• The Relation Between Patients and Biomedicine I think nothing could be done with the growth of a number of online health communities and patients’ deep concern in biomedicine; the challenge is to deal with these phenomena to minimize their negative effects.
• Electric Field Array Micro-System Lab-On-Chip and Biomedical Analysis The differential voltage Vdiff is equal to the product of the applied E and the distance between the split gates Viff=Vin-Vin2=Ed. When E is produced, then the applied E is a function of d.
• Biomedical Researches: Ethics vs. Morals Especially in the researches, dealing with other, poorer nations and people of countries where the respect for human rights is not that high.
• Biomedical Mechanical Engineering and Mechanical Prosthetics One of the first references to the use of prosthetics is observed in the works of the French surgeon, Ambroise Pare, in 1579 where he described the methods of producing prosthetics used by him in […]
• Psychology of Biomedical Fiction The chances of giving a more correct description of hospital incidents and the weaving of crimes into medical life cater to the fancies of the public.
• The Moral Case Against Cloning-for-Biomedical-Research In my view then it is a vain hope that researchers will be able to determine when a human person comes into existence simply by inspecting the biological and genetic evidence about the development of […]
• Biomedical Discovery of DNA Structure The first parts of the book comprised of the opening of Sir Lawrence Bragg, who gave an overview of the entire book and talked about the significance of Francis Crick and James Watson’s discovery with […]
• Biomedical Researcher Career at Immunobiology Ltd. John collaborates with different stakeholders to identify the best opportunities for ImmBio. The respondent was ready to answer my questions.
• Ethics in Biomedical and Nursing Internet Research There is a need to ensure that the Code of Professional Ethics being implemented best suits the protection of human subjects in the context of biomedical research. It is vital to ensure that the Code […]
• Autophagy Mechanisms: Biology and Medicine Breakthrough Prior to Ohsumi’s research, the 1960s saw the discovery of the cell’s capacity to transfer its contents in the enclosed membranes to the lysosome, where the contents are recycled.
• Biomedical Ethical Theories and Principles In general, ethics1 encompasses the theories and principles of particular values as well as the justifications and perceptions of these values.
• Bioanthropology: Culture and Medicine The importance of social and ethnic diversity in the United States today is very high, the awareness of this diversity is widely promoted, yet some culture-specific researches in the American medicine led to racial division […]
• Career in Biomedical Sciences: Opportunities & Prospects For one to qualify as a biomedical scientist, one is usually required to have a degree in Biomedical Science with the prospects of upgrading through graduate school.
• Approaches to Human Illness From a Biomedical Anthropology Perspective In a sense, the biocultural view fronted by Stanford and company can be used to explain the article’s main theme of inequality and human illness as it recognize the fact that both our evolutionary and […]
• The Biomedical Model of Health in Medicine How human beings respond to illness is essential and understanding the concepts of every healing system is vital in combating diseases.
• Biomedicine: Scientific Medicine Prominent in Western Societies
• The Limits of Biomedicine Among the Dagomba of Northern Ghana
• AIDS Stigma and Its Effects Upon the Gay Community and Biomedicine
• Bioethical Governance and Basic Stem Cell Science: Global Biomedicine Economy
• Biomedicine Globalized and Localized: Western Medical Practices in a Mexican Hospital
• Cardiac Biomedicine: Cardiac Hypertrophy and Failure Draft
• Why Biomedical Research on Animals Is Needed
• Chinese Traditional Medicine System and Western Biomedicine Comparative Analysis
• Credibility, Replicability, and Reproducibility in Simulation for Biomedicine and Neuroscience
• Does Alternative Medicine Present a Challenge to Biomedicine
• How Sociological and Lay Ideas About Illness Differ From Those of Biomedicine
• Exploring the Boundaries Between Alternative Medicine and Biomedicine
• Functional Craniology and Brain Evolution: From Paleontology to Biomedicine
• Global Pharmaceutical and Biomedicine Companies
• Sleep, Health, and the Dynamics of Biomedicine
• Toward New Models for Innovative Governance of Biomedicine and Health Technologies
• Statement of Purpose for Biomedical Sciences
• The Era of Biomedicine: Science, Medicine, and Public Health
• The Relevance of Evolutionary Theory in Biomedical Science
• Studying Pain in the Realm of Biomedicine
• Biomedicine and Prevention: A Public Health Perspective
• Examining Western Biomedicine and Shamanism
• Credibility, Replicability, and Reproducibility in Simulation for Biomedicine and Clinical Applications
• Ancient Greek Medical System as the Basis of Biomedicine
• Concerns of a Health Professional in Biomedical Science
• China and the Globalization of Biomedicine
• Combining Hard Sciences With Biomedicine
• The Influence of IT in the Field of Biomedicine
• Career Critique: Comparing Urban Planners and Biomedical Engineers
• Computer Methods and Programs in Biomedicine
• Overview of the Current Trends in Biomedicine
• Animating Biomedicine’s Moral Order: Comprehensive Analysis
• Deep Learning in Bioinformatics and Biomedicine
• Critical Perspectives of Biomedicine, Religious Studies, Art History, Philosophy
• CNS Regeneration, Possible Only Through Bioengineering Advancements
• The New Medical Model: A Renewed Challenge for Biomedicine
• Linking Biomedicine and the Human Condition
• Nanoparticles in Life Sciences and Biomedicine
• Overview of Sex and Gender in Biomedicine
• What Are the Arguments Against Biomedical Research
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IvyPanda. (2024, March 2). 74 Biomedicine Essay Topic Ideas & Examples. https://ivypanda.com/essays/topic/biomedicine-essay-topics/

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• Master of Science in Biomedical Engineering

Projects and Master Thesis in Biomedical Engineering

What are typical master thesis topics.

Students report intermediate results during our yearly Biomedical Industry Day. An overview of this years displayed posters is found here .

Some examples of finalized master theses in biomedical engineering

• Experimental characterisation and finite element modeling of biodegradable magnesium stents
• Development of a planning tool for robot-assisted partial nephrectomy surgery based on 3D reconstructions of kidneys
• Does the lower limb kinematic CGM2.i model form a suitable alternative to the PiG model in a clinical setting
• Targeted drug delivery for liver cancer: modelling the impact of cancer burden on the particle distribution in a patient-specific cirrhotic live
• Development of antibacterial TiO2 coatings on titanium implants by plasma electrolytic oxidation
• 2-oxazoline-based plasma coatings for anti-fouling application
• Improving the adhesion properties of a shoulder implant using plasma technology
• The effect of vagus nerve stimulation on the brain of epilepsy patients
• Diagnosis of depression based on resting state functional MRI
• Towards Individualized Hearing Profiles Using Deep Neural Nets
• Computational models of optogenetic neurostimulation Comparative study of plasma-treated PCL fibers having different diameters and orientations for enhanced peripheral nerve regeneration
• Heterogeneity of the STV in the CAVB dog model for Torsade de Pointes
• Brain-Computer Interfaces using Machine Learning Reducing calibration time in Motor Imagery
• Automatic detection of abnormal behaviour of equines
• Deep Learning in Skin Lesion Classification Tasks
• Zero-Echo Time MR imaging of the pelvis as prior for PET reconstruction
• Radiation dose optimization of CT acquisitions in PET/CT examinations

Rochester News

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Exploring the ethical dilemmas of emergency care on the front lines

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Rachel Whitmoyer brings her work as an emergency medical technician to bear on her philosophy studies at Rochester.

As an emergency medical technician (EMT) since 2020, Rachel Whitmoyer ’24 has helped countless patients facing dire situations. But she also has dealt with less-extreme scenarios, including one man who demanded transport to the hospital via ambulance because of . . . hiccups.

That incident proved annoying and enlightening for Whitmoyer, a double major in physics and philosophy at the University of Rochester who hails from Lebanon, Pennsylvania.

“It’s easy to become frustrated when the area you service is short on first responders and policy requires you to transport non-emergent patients to the hospital,” she says. “But even if a patient isn’t in need of immediate medical care, they may not have the background necessary to recognize that. They can be scared, confused, and stressed.”

Situations like this prompted Whitmoyer to dedicate her senior thesis to exploring the biomedical ethical issues faced by EMTs. “So much of health care emphasizes curing patients as a solitary goal,” she says. “But high-quality patient care cannot exist without realizing that a patient is a person, and not a problem to be solved.”

Ambulances and academia

Whitmoyer’s thesis focuses on a few points: justice considerations in triage and resource allocation in prehospital and hospital settings, the benefits that Emergency Medical Services–initiated refusal of transport protocols have on individuals and communities, and why Do Not Resuscitate (DNR) orders outside of hospitals often don’t honor patients’ autonomy in end-of-life health care decisions.

“My goal is to address how unyielding legal requirements have taken precedence over patient-specific care over the past few decades, and the potential solutions that would allow providers to maintain a balance of both,” Whitmoyer says.

Her research involves synthesizing the results from previous studies and analyzing them from an ethical perspective. “For instance, I’ve been utilizing studies quantifying unnecessary ambulance use and studies discussing unwanted resuscitation attempts in patients with DNR orders,” she says. “Being able to connect with subject-specific University librarians was extremely helpful in beginning the research process, as well as what I learned in my introductory writing and philosophy courses.”

Cases lacking genuine medical need can stretch limited resources and compromise the ability of EMTs to attend to genuine emergencies.

Pennsylvania is one of 13 states that deem EMS an essential service eligible for state funding. No one can be denied a ride to the hospital in an ambulance—although not everyone needs it, hiccups or otherwise.

“People assume that they will get to the front of the line in the emergency department if they arrive in an ambulance,” Whitmoyer says. “That’s not true, unless they’re in a cardiac or high-acuity situation. Anyone not facing a life-threatening situation usually has to wait.”

From EMT to physics and philosophy—by way of the Rochester curriculum

William FitzPatrick , the Gideon Webster Burbank Professor of Intellectual and Moral Philosophy at Rochester and Whitmoyer’s thesis adviser, says she’s “a particularly impressive and ambitious student” with an exceptional work ethic.

“Combining hard science, philosophy, and medicine is extraordinary, especially with the addition of a senior thesis project,” he adds.

FitzPatrick says Whitmoyer’s thesis explores interesting and timely questions about how to balance deference to patient demands for emergency hospital transportation with professional judgment concerning genuine medical need.

“Current policy is weighted in favor of deferring to patient demands,” he says. “But in cases lacking genuine medical need this can stretch resources and compromise the ability of EMTs to attend to genuine emergencies; on the other hand, refusal of transport in such cases raises its own problems unless the underlying social challenges and vulnerabilities are also addressed.”

Whitmoyer took classes with FitzPatrick in her sophomore and junior years and wrote a paper about the limitations of obtaining informed consent in medical emergencies. She so enjoyed doing the research and connecting it to her experiences as an EMT that she decided to take on an additional project this year to explore more of the ethical issues in pre-hospital emergency medicine.

Whitmoyer entered the University as a physics major in 2020 but added philosophy as a second major her sophomore year. She says Rochester’s flexible undergraduate curriculum made it possible to major in two non-related fields. “Going into my first semester and being able to choose classes and explore my interests gave me lots of flexibility,” she says. “I took some philosophy courses and just fell in love with it.”

One of the early impactful classes was Philosophy 105: Reason and Argument, with associate professor Zeynep Soysal.

“That class taught me that learning how to construct a good argument makes it much easier not only to effectively communicate your ideas but also to analyze information coming from other sources,” Whitmoyer says.

Answering the call

Whitmoyer took an EMT class in high school and became certified in June 2020, when the COVID-19 pandemic was surging. She’s affiliated with two companies back in Pennsylvania—one paid and one volunteer—and during summers she can work up to 60 hours per week. She usually works 12-hour shifts and always has at least one partner.

The first step when responding to a call is determining the patient’s level of consciousness and the reason EMTs were summoned. Whitmoyer may have to administer oxygen or medication or perform life-saving interventions to control high-acuity issues relating to airway, breathing, or circulation. The EMTs contact the hospital’s emergency department via radio to alert them of their impending arrival and provide a patient care report that details pertinent findings or interventions performed.

“My favorite part is getting to advocate for my patients and help mitigate stress in some of the most emotional moments of their lives,” she says. “I am often a stranger to many of the people I meet on scene and view it as an immense honor and privilege to be given their trust. Driving with lights and sirens on is pretty cool, too.”

Whitmoyer plans to pursue a career as an emergency medicine physician, which she will train for as she completes a military medical residency under the US Army’s Health Professions Scholarship Program after graduating medical school.

“My grandfather is an Army veteran, and many other family members have served,” she says.

Whitmoyer doesn’t rule out continuing as an EMT long term, either.

“I’d love to be able to pick up shifts if time allows,” she says. “The work is so rewarding.”

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