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Clinical Research Associate

Clinical Research Associate in the Department of Psychosis Studies Job id: 079105 Salary: £35,254 - £53,132, plus £2,162 London Weighting Allowance per annum Business unit: IoPPN Department: Psychosis Studies Location: Denmark Hill Campus Category: Research

This is an exciting opportunity to gain and develop research skills. The successful candidate will play a key role in innovative studies taking an exciting new immunologically-focussed approach to understanding and treating neuropsychiatric disorders. They will join Dr Tom Pollak’s research group. 

Our team believes the immune system may hold clues to how psychosis and other psychiatric disorders are caused and how people respond to treatments. We will investigate blood and cerebrospinal fluid from patients, and use machine-learning to identify the treatment-relevant immune processes, with an emphasis on immune cells, autoantibodies and inflammatory markers. If we can show causal links, our work could guide future targeted immune-based interventions.

The studies involve subject recruitment and collection of clinical data and other data, and biosamples (blood and cerebrospinal fluid) from patients. The main focus is on an exciting new prospective, longitudinal study aiming to assess the immunological effects of antipsychotic treatment. It is being led by a team from KCL and the Francis Crick Institute and is unique for its interdisciplinary nature, combining expertise from clinical psychiatry, immunology and neuroscience, with significant ongoing input from people with lived experience of psychosis. The post-holder will have a central role in the team and will contribute to its dynamic, friendly and supportive culture, and to its strong spirit of multidisciplinary scientific enquiry.

The lead site will be the Institute of Psychiatry, Psychology and Neuroscience (IoPPN) at King’s College London, one of the most prestigious research institutions dedicated to discovering what causes mental illness and diseases of the brain. The main study will involve 2 academic sites (King’s College London and the Francis Crick Institute) and will recruit from clinical sites around England and Wales. Recruitment will be the most challenging part of the trial, therefore the post-holder will have a key role in assisting with recruitment-related issues. 

The post-holder will have opportunities to get involved in data analysis and develop their research interests within the projects. Training in research methods will be provided, and the post-holder will develop skills in using gold-standard diagnostic and clinical ratings, which will be useful for future research and clinical practice.  

Working closely with the Lead Investigators, the successful candidate will ensure the successful conduct and completion of the research programme. He/she will contribute to the collection and analysis of data and play a key role in the assessment and monitoring of patients. He/she will also work closely with other research staff in the project and foster effective collaborative working relationships with the local and regional services for psychosis, as well as neurology, rheumatology and neuropsychiatry services. The successful candidate will also be encouraged to develop their own research interests, deliver teaching on immunopsychiatric topics and will have the opportunity to join a unique and growing clinical immunopsychiatry service.

This post will be offered on a full-time, fixed term contract for 12 months. There is some flexibility in start date.

GMC registration is a requirement.

Contact details: Esme Young. [email protected]  

Closing date: 5th January 2024.

To apply, please click “Apply Now”.

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Clinical Research MRes/PG Cert

The Florence Nightingale Faculty of Nursing, Midwifery and Palliative Care at King's is a world-leading centre for applied and allied healthcare, clinical research and education. Our focus is on training the healthcare leaders of the future, with a strong commitment to providing post-qualification programmes of the highest quality. The Clinical Research MRes and PGCert is a multi-disciplinary course aimed at practitioners who wish to develop their clinical or academic research careers. The course seeks to enhance the skills and knowledge needed for supporting, delivering and integrating research into clinical practice, as well as fostering evidence-based practice. Practitioners with the appropriate innovation and critical-thinking skills may be supported to undertake further study at MPhil/PhD level with the aim of developing a future clinical academic career.

Key benefits

• You will be studying at the no.1 Nursing Faculty in the UK and 2nd in the world (2023 QS World University Rankings by subject).
• Located in the heart of London, across four of King’s Thames-side campuses (Waterloo, Strand, St Thomas’ and Guy’s) and the Denmark Hill Campus in South London.
• Lectures delivered by experienced multi- disciplinary researchers on contemporary issues in the conduct and utilisation of health, clinical and social care research.
• Support will be given to circulate work relating to your studies, predominantly through publication in high-quality peer-reviewed journals, with the opportunity to develop your research into a PhD Fellowship application.
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Clinical Research Associate - phase 1 experience required

• Location: London
• Categories Clinical Monitoring
• __vacancyopjusttionswidget.opt-Business Area__ ICON Strategic Solutions
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About the role, this vacancy has now expired. please see similar roles below....

Role: Clinical Research Associate 

Location: South of the UK (ideally London based & phase 1 experience required)

Fully sponsor dedicated

ICON plc is a world-leading healthcare intelligence and clinical research organisation. From molecule to medicine, we advance clinical research providing outsourced services to pharmaceutical, biotechnology, medical device and government and public health organisations. With our patients at the centre of all that we do, we help to accelerate the development of drugs and devices that save lives and improve quality of life. Our people are our greatest strength, are at the core of our culture, and the driving force behind our success. ICON people have a mission to succeed and a passion that ensures what we do, we do well.

As a Clinical Research Associate, you will be dedicated to one of our global Healthcare clients who have a strong legacy of innovation and leading the way within a specialist therapeutic area. They display an ongoing commitment to changing the lives of patients and the accessibility of products in order to change the lives of those that need them

The Clinical Research Associate is ultimately responsible for the successful management of investigator sites and monitoring activities for assigned clinical studies throughout the trial lifecycle.

Key responsibilities include:

• Full ownership of investigator sites for assigned studies, with responsibility for the successful management of the site right through to close-out, in accordance with the clinical monitoring plan.
• Developing effective relationships with investigator site staff to ensure that key clinical metrics are met.
• Ensuring integrity of clinical data through an ability to sufficiently maintain site tracking records and working diligently to relevant guidelines.

An experienced, ambitious self-starter looking for the opportunity to prove yourself in an embedded role at one of the largest pharmaceutical companies.

Here at ICON we want our employees to succeed and ensure that they are set up for this success through constant training, development and support.

To enable success in this position you will have:

• Prior experience of working in investigator site management, including conducting monitoring visits, from either a pharmaceutical company or a CRO environment.
• A working knowledge of ICH-GCP guidelines and local and international regulatory requirements is essential
• You will be educated to degree level in a life science discipline or be a licensed healthcare professional.

Benefits of Working in ICON: Our success depends on the knowledge, capabilities and quality of our people. That’s why we are committed to developing our employees in a continuous learning culture – one where we challenge you with engaging work and where every experience adds to your professional development. At ICON, our focus is to provide you with a comprehensive and competitive total reward package that comprises, not only an excellent level of base pay, but also a wide range of variable pay and recognition programs. In addition, our best in class employee benefits, supportive policies and wellbeing initiatives are tailored to support you and your family at all stages of your career - both now, and into the future. ICON, including subsidiaries, is an equal opportunity and inclusive employer and is committed to providing a workplace free of discrimination and harassment. All qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or in order to perform the essential functions of a position, please let us know.

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