COMMENTS

  1. Big Data Application in Biomedical Research and Health Care: A Literature Review

    Abstract. Big data technologies are increasingly used for biomedical and health-care informatics research. Large amounts of biological and clinical data have been generated and collected at an unprecedented speed and scale. For example, the new generation of sequencing technologies enables the processing of billions of DNA sequence data per day ...

  2. Big Data Application in Biomedical Research and Health Care: A

    The ecosystem of biomedical big data comprises many different levels of data sources to create a rich array of data for researchers. For example, ... Genta and Sonnenberg 77 provided an overview of big data in gastroenterology research, stating that the big data method is a new tool for finding significant association among large amounts of ...

  3. A review of big data and medical research

    In this descriptive review, we highlight the roles of big data, the changing research paradigm, and easy access to research participation via the Internet fueled by the need for quick answers. Universally, data volume has increased, with the collection rate doubling every 40 months, ever since the 1980s. 4 The big data age, starting in 2002 ...

  4. Biomedical Big Data Technologies, Applications, and Challenges for

    The explosive expansion of biomedical big data has ushered in a wealth of opportunities and challenges in the domains of knowledge discovery within biomedical big data and its translational applications in precision medicine. Within the realm of precision medicine, biomedical big data is considered one of the most crucial and challenging ...

  5. Big data: Historic advances and emerging trends in biomedical research

    Abstract. Big data is transforming biomedical research by integrating massive amounts of data from laboratory experiments, clinical investigations, healthcare records, and the internet of things. Specifically, the increasing rate at which information is obtained from omics technologies (genomics, epigenomics, transcriptomics, proteomics ...

  6. Big data in basic and translational cancer research

    Common data types. There are five basic data types in cancer research: molecular omics data, perturbation phenotypic data, molecular interaction data, imaging data, and textual data. Molecular ...

  7. Big Data Application in Biomedical Research and Health Care: A ...

    The application of big data in health care is a fast-growing field, with many new discoveries and methodologies published in the last five years. In this paper, we review and discuss big data application in four major biomedical subdisciplines: (1) bioinformatics, (2) clinical informatics, (3) imaging informatics, and (4) public health informatics.

  8. Big Data Application in Biomedical Research and Health Care: A

    The application of big data in health care is a fast-growing field, with many new discoveries and methodologies published in the last five years. In this paper, we review and discuss big data application in four major biomedical subdisciplines: (1) bioinformatics, (2) clinical informatics, (3) imaging informatics, and (4) public health informatics.

  9. PDF Big Data in Biomedical Research

    Biomedical research has for a long time involved large datasets. However, big data and novel analytics approaches have been increasingly emphasised as sig-nificant trends (see also Parry and Greenhough 2018, 107ff.). Big data-driven research projects draw on data retrieved from, for instance, social networking

  10. Bioinformatics, Big Data, and Cancer

    The volume of biological data collected during the course of biomedical research has exploded, thanks in large part to powerful new research technologies. ... Democratizing Big Data for Cancer Research. As a federal agency, NCI is uniquely positioned to democratize access to cancer research data.

  11. Big data in biomedicine

    Research organizations are assembling cloud-based 'information commons' to standardize, store and share the data ... Biomedical Big Data: New Models of Control Over Access, Use and Governance ...

  12. Big data in healthcare: management, analysis and future prospects

    Big data in biomedical research. A biological system, such as a human cell, exhibits molecular and physical events of complex interplay. In order to understand interdependencies of various components and events of such a complex system, a biomedical or biological experiment usually gathers data on a smaller and/or simpler component.

  13. Big Data, Biomedical Research, and Ethics Review: New Challenges for

    Big data research relies on large-scale databases, multiplication of data sources, advanced storage capacity, and novel computational tools that allow for high-velocity data analytics. 2 In the biomedical domain, big data trends are enabled by and allow for advances in areas such as whole genome sequencing, brain imaging, mobile health, and ...

  14. Big data in biomedicine: 4 big questions

    1. How can long-term access to biomedical data that are vital for research be improved? Why it matters Data storage may be getting cheaper, particularly in cloud computing, but the total costs of ...

  15. Biomedical Data Science

    Biomedical Data Science involves the analysis of large-scale biomedical datasets to understand how living systems function. Our academic and research programs in Biomedical Data Science center on developing new data analysis technologies in order to understand disease mechanisms and provide improved health care at lower costs.

  16. The Ethics of Big Data: Current and Foreseeable Issues in Biomedical

    'Big Data' covers a vast variety of phenomena focused on the analysis of large datasets. Data types and applications can be found in areas such as intelligence analytics (Mahajan et al. 2012), behaviour and preference modelling (Coll 2014, p. 1257; Lomborg and Bechmann 2014), sustainability studies (Mahajan et al. 2012), online and offline commerce, biomedical research and healthcare, and ...

  17. PDF On Big-Data Analytics in Biomedical Research

    In recent years, big data analytics has received much attention in the area of healthcare related biomedical research and development. Big data analytics enables research organizations to analyze a mix of structured and unstructured data for identifying valuable medical information and insights in healthcare related biomedical research and ...

  18. Big Data Application in Biomedical Research and Health Care: A

    In the biomedical informatics domain, big data is a new para-digm and an ecosystem that transforms case-based studies to large-scale, data-driven research. It is widely accepted that the characteristics of big data are defined by three major features, commonly known as the 3Vs: volume, variety, and velocity.

  19. Big Data for Biomedical Research of Inflammatory Diseases

    The challenges of big data in biomedical research of pharmacology and medicine include big data capturing, analysis, information retrieval, transfer and visualisation, and information privacy protection (Elgendy and Elragal, 2014). The research domains have encompassed the amount, variety, and velocity of big data in addition to other pertinent ...

  20. Big Data Privacy in Biomedical Research

    This paper reviews relevant topics in the context of biomedical research. We discuss privacy preserving technologies related to (1) record linkage, (2) synthetic data generation, and (3) genomic data privacy. We also discuss the ethical implications of big data privacy in biomedicine and present challenges in future research directions for ...

  21. Combining biomedical data from breast cancer patients could lead to

    Studying combined data from the UK Biobank, a unique record of patient information from more than half a million Britons, could help make "groundbreaking discoveries" in the understanding and ...

  22. Yale Is Lead Institution in the 'All of Us' Research Consortium

    Participants can share a wide range of data from biosamples, survey responses, physical measurements, electronic health records (EHRs), and wearable devices. These data are made broadly available to registered researchers through the program's Researcher Workbench, fostering biomedical research discoveries and promoting health equity.

  23. NIAID Emerging Leaders in Data Sciences Fellowship

    This fellowship addresses a critical need at NIAID for expertise in data science and ability to apply those skills to the NIAID mission. It aims to establish a cadre of talented data scientists (i.e., expertise in biomedical informatics, computational biology, epidemiology, computer science, engineering, applied mathematics, statistics, or related fields) with a keen interest in applying their ...

  24. Biomedical Big Data: New Models of Control Over Access, Use and

    Biomedical big data range from data generated by health services, public health activities, and biomedical research, to data registering exposure to environmental factors like sunlight or pollution, or data revealing lifestyle, socioeconomic conditions, and behavioural patterns, such as data from wellness and fitness applications, social media ...

  25. First Ascent Biomedical Presents Findings from Clinical ...

    MIAMI--(BUSINESS WIRE)-- First Ascent Biomedical announced findings from ongoing clinical studies conducted in partnership with Florida International University, examining the company's Functional Precision Medicine (FPM) platform in adult and pediatric patients with difficult-to-treat cancers.The study findings were presented during poster sessions at the 2024 American Society of Clinical ...

  26. [2405.15122] Generalizable and Scalable Multistage Biomedical Concept

    Background: Biomedical entity normalization is critical to biomedical research because the richness of free-text clinical data, such as progress notes, can often be fully leveraged only after translating words and phrases into structured and coded representations suitable for analysis. Large Language Models (LLMs), in turn, have shown great potential and high performance in a variety of ...

  27. Evaluation of alginate‐coated β‐tricalcium phosphate fiber scaffold for

    Journal of Biomedical Materials Research Part B: Applied Biomaterials is an interdisciplinary journal on biomaterials in medical devices & other clinical applications. Abstract Ex vivo tissue engineering is an effective therapeutic approach for the treatment of severe cartilage diseases that require tissue replenishment or replacement.

  28. Big Data, Biomedical Research, and Ethics Review: New Challenges for

    The increased use of big data in the medical field has shifted the way in which biomedical research is designed and carried out. The novelty of techniques and methods brought by big data research brings new challenges to institutional review boards (IRBs). Yet it is unclear if IRBs should be the responsible oversight bodies for big data ...

  29. The state of AI in early 2024: Gen AI adoption spikes and starts to

    If 2023 was the year the world discovered generative AI (gen AI), 2024 is the year organizations truly began using—and deriving business value from—this new technology.In the latest McKinsey Global Survey on AI, 65 percent of respondents report that their organizations are regularly using gen AI, nearly double the percentage from our previous survey just ten months ago.

  30. Big Data Privacy in Biomedical Research

    This paper reviews relevant topics in the context of biomedical research. We discuss privacy preserving technologies related to (1) record linkage, (2) synthetic data generation, and (3) genomic data privacy. We also discuss the ethical implications of big data privacy in biomedicine and present challenges in future research directions for ...