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One of the hardest parts of writing a research paper can be just finding a good topic to write about. Fortunately we've done the hard work for you and have compiled a list of 113 interesting research paper topics. They've been organized into ten categories and cover a wide range of subjects so you can easily find the best topic for you.

In addition to the list of good research topics, we've included advice on what makes a good research paper topic and how you can use your topic to start writing a great paper.

What Makes a Good Research Paper Topic?

Not all research paper topics are created equal, and you want to make sure you choose a great topic before you start writing. Below are the three most important factors to consider to make sure you choose the best research paper topics.

#1: It's Something You're Interested In

A paper is always easier to write if you're interested in the topic, and you'll be more motivated to do in-depth research and write a paper that really covers the entire subject. Even if a certain research paper topic is getting a lot of buzz right now or other people seem interested in writing about it, don't feel tempted to make it your topic unless you genuinely have some sort of interest in it as well.

#2: There's Enough Information to Write a Paper

Even if you come up with the absolute best research paper topic and you're so excited to write about it, you won't be able to produce a good paper if there isn't enough research about the topic. This can happen for very specific or specialized topics, as well as topics that are too new to have enough research done on them at the moment. Easy research paper topics will always be topics with enough information to write a full-length paper.

Trying to write a research paper on a topic that doesn't have much research on it is incredibly hard, so before you decide on a topic, do a bit of preliminary searching and make sure you'll have all the information you need to write your paper.

#3: It Fits Your Teacher's Guidelines

Don't get so carried away looking at lists of research paper topics that you forget any requirements or restrictions your teacher may have put on research topic ideas. If you're writing a research paper on a health-related topic, deciding to write about the impact of rap on the music scene probably won't be allowed, but there may be some sort of leeway. For example, if you're really interested in current events but your teacher wants you to write a research paper on a history topic, you may be able to choose a topic that fits both categories, like exploring the relationship between the US and North Korea. No matter what, always get your research paper topic approved by your teacher first before you begin writing.

113 Good Research Paper Topics

Below are 113 good research topics to help you get you started on your paper. We've organized them into ten categories to make it easier to find the type of research paper topics you're looking for.

Arts/Culture

  • Discuss the main differences in art from the Italian Renaissance and the Northern Renaissance .
  • Analyze the impact a famous artist had on the world.
  • How is sexism portrayed in different types of media (music, film, video games, etc.)? Has the amount/type of sexism changed over the years?
  • How has the music of slaves brought over from Africa shaped modern American music?
  • How has rap music evolved in the past decade?
  • How has the portrayal of minorities in the media changed?

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Current Events

  • What have been the impacts of China's one child policy?
  • How have the goals of feminists changed over the decades?
  • How has the Trump presidency changed international relations?
  • Analyze the history of the relationship between the United States and North Korea.
  • What factors contributed to the current decline in the rate of unemployment?
  • What have been the impacts of states which have increased their minimum wage?
  • How do US immigration laws compare to immigration laws of other countries?
  • How have the US's immigration laws changed in the past few years/decades?
  • How has the Black Lives Matter movement affected discussions and view about racism in the US?
  • What impact has the Affordable Care Act had on healthcare in the US?
  • What factors contributed to the UK deciding to leave the EU (Brexit)?
  • What factors contributed to China becoming an economic power?
  • Discuss the history of Bitcoin or other cryptocurrencies  (some of which tokenize the S&P 500 Index on the blockchain) .
  • Do students in schools that eliminate grades do better in college and their careers?
  • Do students from wealthier backgrounds score higher on standardized tests?
  • Do students who receive free meals at school get higher grades compared to when they weren't receiving a free meal?
  • Do students who attend charter schools score higher on standardized tests than students in public schools?
  • Do students learn better in same-sex classrooms?
  • How does giving each student access to an iPad or laptop affect their studies?
  • What are the benefits and drawbacks of the Montessori Method ?
  • Do children who attend preschool do better in school later on?
  • What was the impact of the No Child Left Behind act?
  • How does the US education system compare to education systems in other countries?
  • What impact does mandatory physical education classes have on students' health?
  • Which methods are most effective at reducing bullying in schools?
  • Do homeschoolers who attend college do as well as students who attended traditional schools?
  • Does offering tenure increase or decrease quality of teaching?
  • How does college debt affect future life choices of students?
  • Should graduate students be able to form unions?

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  • What are different ways to lower gun-related deaths in the US?
  • How and why have divorce rates changed over time?
  • Is affirmative action still necessary in education and/or the workplace?
  • Should physician-assisted suicide be legal?
  • How has stem cell research impacted the medical field?
  • How can human trafficking be reduced in the United States/world?
  • Should people be able to donate organs in exchange for money?
  • Which types of juvenile punishment have proven most effective at preventing future crimes?
  • Has the increase in US airport security made passengers safer?
  • Analyze the immigration policies of certain countries and how they are similar and different from one another.
  • Several states have legalized recreational marijuana. What positive and negative impacts have they experienced as a result?
  • Do tariffs increase the number of domestic jobs?
  • Which prison reforms have proven most effective?
  • Should governments be able to censor certain information on the internet?
  • Which methods/programs have been most effective at reducing teen pregnancy?
  • What are the benefits and drawbacks of the Keto diet?
  • How effective are different exercise regimes for losing weight and maintaining weight loss?
  • How do the healthcare plans of various countries differ from each other?
  • What are the most effective ways to treat depression ?
  • What are the pros and cons of genetically modified foods?
  • Which methods are most effective for improving memory?
  • What can be done to lower healthcare costs in the US?
  • What factors contributed to the current opioid crisis?
  • Analyze the history and impact of the HIV/AIDS epidemic .
  • Are low-carbohydrate or low-fat diets more effective for weight loss?
  • How much exercise should the average adult be getting each week?
  • Which methods are most effective to get parents to vaccinate their children?
  • What are the pros and cons of clean needle programs?
  • How does stress affect the body?
  • Discuss the history of the conflict between Israel and the Palestinians.
  • What were the causes and effects of the Salem Witch Trials?
  • Who was responsible for the Iran-Contra situation?
  • How has New Orleans and the government's response to natural disasters changed since Hurricane Katrina?
  • What events led to the fall of the Roman Empire?
  • What were the impacts of British rule in India ?
  • Was the atomic bombing of Hiroshima and Nagasaki necessary?
  • What were the successes and failures of the women's suffrage movement in the United States?
  • What were the causes of the Civil War?
  • How did Abraham Lincoln's assassination impact the country and reconstruction after the Civil War?
  • Which factors contributed to the colonies winning the American Revolution?
  • What caused Hitler's rise to power?
  • Discuss how a specific invention impacted history.
  • What led to Cleopatra's fall as ruler of Egypt?
  • How has Japan changed and evolved over the centuries?
  • What were the causes of the Rwandan genocide ?

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  • Why did Martin Luther decide to split with the Catholic Church?
  • Analyze the history and impact of a well-known cult (Jonestown, Manson family, etc.)
  • How did the sexual abuse scandal impact how people view the Catholic Church?
  • How has the Catholic church's power changed over the past decades/centuries?
  • What are the causes behind the rise in atheism/ agnosticism in the United States?
  • What were the influences in Siddhartha's life resulted in him becoming the Buddha?
  • How has media portrayal of Islam/Muslims changed since September 11th?

Science/Environment

  • How has the earth's climate changed in the past few decades?
  • How has the use and elimination of DDT affected bird populations in the US?
  • Analyze how the number and severity of natural disasters have increased in the past few decades.
  • Analyze deforestation rates in a certain area or globally over a period of time.
  • How have past oil spills changed regulations and cleanup methods?
  • How has the Flint water crisis changed water regulation safety?
  • What are the pros and cons of fracking?
  • What impact has the Paris Climate Agreement had so far?
  • What have NASA's biggest successes and failures been?
  • How can we improve access to clean water around the world?
  • Does ecotourism actually have a positive impact on the environment?
  • Should the US rely on nuclear energy more?
  • What can be done to save amphibian species currently at risk of extinction?
  • What impact has climate change had on coral reefs?
  • How are black holes created?
  • Are teens who spend more time on social media more likely to suffer anxiety and/or depression?
  • How will the loss of net neutrality affect internet users?
  • Analyze the history and progress of self-driving vehicles.
  • How has the use of drones changed surveillance and warfare methods?
  • Has social media made people more or less connected?
  • What progress has currently been made with artificial intelligence ?
  • Do smartphones increase or decrease workplace productivity?
  • What are the most effective ways to use technology in the classroom?
  • How is Google search affecting our intelligence?
  • When is the best age for a child to begin owning a smartphone?
  • Has frequent texting reduced teen literacy rates?

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How to Write a Great Research Paper

Even great research paper topics won't give you a great research paper if you don't hone your topic before and during the writing process. Follow these three tips to turn good research paper topics into great papers.

#1: Figure Out Your Thesis Early

Before you start writing a single word of your paper, you first need to know what your thesis will be. Your thesis is a statement that explains what you intend to prove/show in your paper. Every sentence in your research paper will relate back to your thesis, so you don't want to start writing without it!

As some examples, if you're writing a research paper on if students learn better in same-sex classrooms, your thesis might be "Research has shown that elementary-age students in same-sex classrooms score higher on standardized tests and report feeling more comfortable in the classroom."

If you're writing a paper on the causes of the Civil War, your thesis might be "While the dispute between the North and South over slavery is the most well-known cause of the Civil War, other key causes include differences in the economies of the North and South, states' rights, and territorial expansion."

#2: Back Every Statement Up With Research

Remember, this is a research paper you're writing, so you'll need to use lots of research to make your points. Every statement you give must be backed up with research, properly cited the way your teacher requested. You're allowed to include opinions of your own, but they must also be supported by the research you give.

#3: Do Your Research Before You Begin Writing

You don't want to start writing your research paper and then learn that there isn't enough research to back up the points you're making, or, even worse, that the research contradicts the points you're trying to make!

Get most of your research on your good research topics done before you begin writing. Then use the research you've collected to create a rough outline of what your paper will cover and the key points you're going to make. This will help keep your paper clear and organized, and it'll ensure you have enough research to produce a strong paper.

What's Next?

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These recommendations are based solely on our knowledge and experience. If you purchase an item through one of our links, PrepScholar may receive a commission.

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Christine graduated from Michigan State University with degrees in Environmental Biology and Geography and received her Master's from Duke University. In high school she scored in the 99th percentile on the SAT and was named a National Merit Finalist. She has taught English and biology in several countries.

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94 Newspaper Essay Topic Ideas & Examples

🏆 best newspaper topic ideas & essay examples, 💡 simple & easy newspaper essay titles, 👍 good research topics about newspaper, 📌 most interesting newspaper topics to write about.

  • Newspaper Industry and the Internet Most of the readers are now finding the news in newspapers somewhat stale considering that the news on the internet is instant, fresh and immediate.
  • Raw Materials for Newspaper Manufacturing Resins bind other components of the ink and form a film for binding the ink and the paper. Transportation of wood, paper fiber, and ink is also necessary to deliver the raw material to the […]
  • War and Violence Metaphors in Newspaper Headlines For both purposes, the use of metaphorical language in headlines is crucial to catch the people’s attention and to trigger a chain of association that will direct the readers’ focus to a particular side of […]
  • Newspaper Article Analysis The topic can make one to believe that there is a certain group trying to overthrow the government in place but, this is not the case.
  • Leadership at The New York Times Newspaper Wisdom comes in handy when the leader is balancing the interests of shareholders such that the leader’s actions lead to the common good.
  • Newspapers, Books, Magazines as Media Forms The aim of the current research is to analyze the role of the media and assess the importance of newspapers, books, and magazines as media forms.
  • Newspaper Readership Decline Factors Basing on the apparent trends of newspaper readership, the media systems predict that the future of newspapers seems untenable because of the increasing decline in newspaper readership.
  • Media Convergence and Newspaper Publication The convergence of media that resulted in the digitized form of The New York Times and Washington Post is the testament to the power of Information Technology and the changing needs of people. In this […]
  • The Decline of Newspapers in the US The decline of newspapers in the US is attributed to decrease in readership of newspaper across the country. The increasing economic challenges experienced by newspaper companies have made the prices of their stocks to decline, […]
  • Newspaper Collection and General Recycling GR has a higher responsibility for quality due to the specifics of the general disposal and specifies the quantity and class of the material before collection.
  • A Healthcare Study in the Vancouver Sun Newspaper The independent variable was the participants’ cannabis use, and the objective/subjective factors were the effectiveness of sleep, the rapidity of falling asleep, and the number of awakenings at night.
  • Newspaper Article and Scientific Research: Comparison The text of the research article is obviously not so easy to read compared to the text from the New York Post.
  • Newspaper Coverage of Adolf Hitler’s Death It marks the end of the era of the terrible events of the Holocaust, the seizure of Poland, the extermination of millions of people.
  • Research of Lifespan in Newspaper The major focus of the study was to identify the cities with the shortest rate of life duration. The researchers used the observational research method and qualitative research design as they gathered the data from […]
  • Addressing Several Law Cases and a Newspaper Article For instance, the teleological approach suggests that the decision of the Nevada Supreme Court was reasonable and rightful because it was the best option to bring the highest level of good and the least level […]
  • Newspaper Press Apogee in the Early 20th Century The development of more effective and quick printing methods resulted in the rise of the use of newspapers all over the world and the newspaper press was at all times prepared to capture any events […]
  • Muslim Women’s Representation in America in Newspapers This article is devoted to studying statistics that link various areas of the lives of Muslim women and their employment in America.
  • Biases and Sources in Newspaper Articles About the Coronavirus The coronavirus is unpredictable and hard to control, and people have to cooperate, communicate, and exchange available information to predict the growth of complications and health-related problems.
  • “Westside Today” and “Gazette Newspapers”: Comparative Characteristics The popularity of newspapers depends on the predominance of certain groups in the area, the values that have established themselves in that particular community and the ability of the newspaper to interest the reader by […]
  • Internet Impact on Journalism: Print vs. Online Newspapers The purpose of the investigation is to examine the impact of the Internet on journalism with the help of analyzing the role of print newspapers, online newspapers, and social networking in presenting the information and […]
  • Newspaper Interpretations of Dred Scott vs. Sanford In retrospect, it is obvious that Northern anti-slavery interpretations of the Dred Scott decision were much more accurate than Southern pro-slavery interpretations.
  • Fabricating Facts in a Daily Newspaper As the chief editor of a large metropolitan daily newspaper, one is entitled to explaining to the audience the various roles of the media in the society and its capacity of information coverage in all […]
  • Past Newspaper Articles Analysis: The New York Times In comparison to the previous stories published 100 years ago, New York Times has a habit of making the chaotic and the most important issues, headlines.
  • Newspapers: Commercialism and Information It is by virtue of this final that it comes evident the lack of government’s support in terms of subsidies to the press in the current regarded capitalist system full of democracy but only makes […]
  • The New York Times Newspaper’s Strategic Management Considering the analysis of the business performance, and the related aspects of the publishing business, there is a strong necessity to emphasize that the New York Times should focus on the issues of strategic management […]
  • Internet and Traditional Newspaper Industry First of all, in order to understand the major tendencies in changing media popularity, it is necessary to look at the differences in technological processes of news production on the Web and in traditional newspapers.
  • Newspaper Accounts of First Nations People As the article is overloaded with details, one can assume that the author intentionally directs the reader’s attention to the industriousness with which the entities of judicial and executive power have been trying to keep […]
  • Newspaper Articles on Financial Accounting Analysis Though they are the leading companies in the world they only cover around 1/3 of the Bangladesh market. So in the light of the above discussion it is crystal clear the local firm of Bangladesh […]
  • Newspaper Coverage of Japan-America Internment in WW2 and the Civil Rights Movement The media covered this because this movement persuaded whites to join them in their mass protests and they were killed in the event.
  • News Nowadays: Digitalization of Newspapers However, the digitalization of the newspapers has adversely impacted the quality of news, as it has led to the rise of fake news.
  • How to Identify and Locate a Newspaper in E- Databases? The results showed that a search statement consisting of three concepts, features of the search databases, and the use of basic and advanced searches consisting of ley words, concatenated words, and indexing were necessary to […]
  • Jonesboro Newspaper’s Budget and Cash Flow A budget enables an individual to forecast the amount of money to be realized upon the execution of a given undertaking. A part of the income from the company will be used to cater for […]
  • Macroeconomics in 2010 Newspaper Articles The article has its basis on the recent global financial crisis, which started in the United States and spread to other parts of the world.
  • Alzheimer’s Disease in Newspaper Articles The number of patients diagnosed with Alzheimer’s and diabetes in the United States, and indeed globally, has increased significantly in the last few years. This means that the main interest of such collaboration is to […]
  • Portrayal of Ernesto Che Guevara by American Newspapers In his article, Llosa remarks that people do not know the real character of Guevara’s actions and therefore “cling to a myth”.
  • Chernobyl Disaster in New York Newspapers Still, media statements from 1986, and especially the day of the initial report, can be considered the first reaction of the media to the accident.
  • Newspaper Industry and Its Challenges Nowadays, the majority of researchers who are concerned about the problem of the dissemination of information in the modern world acknowledge that news organizations are having significant financial troubles related to changes on a global […]
  • Local Newspaper and Its Social Media Advertising The exploration of the role of advertising on the Internet in the process of raising the profitability of the company contributes to a better understanding of the mechanism used by the World Wide Web for […]
  • Financial Times Newspaper Brand Marketing The Financial Times is a British newspaper that is published in London that primarily focuses on the financial market in the United Kingdom and the rest of the world.
  • Newspapers’ Discussion: School Desegregation In spite of the fact that many newspaper authors covered the school desegregation events rather subjectively, the approaches to discussing the process of school desegregation in the American states are different in relation to the […]
  • Newspaper Report and TV Report: Comparison and Contrast Conversely, the audience relates to the story through the tone of voice of the reporter as well as the appearance of the characters in the TV report.
  • Ideologies in Newspaper Writing On the contrary, ideology is linked to the ruling system since the distortion implicated on the ideology reflects the interest of the rulers.
  • Newspapers Are Under Attack From The Net. What Strategies Might Be Followed To Survive? The way to go for the newspapers is to provide the detailed facts that blogs and short articles on the internet do not provide.
  • Constitutional Rights for Campus Newspaper Editors The code of conduct should always be in line with the provisions in the constitution of the country especially in areas where the rights of the students are likely to be affected or are threatened.
  • Michigan Newspapers’ Biased Coverage of Jewish Persecution in Germany In the period of 1933-1939, which encompasses Hitler’s rise to power that saw a sustained persecution of Jews in Germany and the pogroms, which culminated in the Night of The Broken Glass, the reception of […]
  • Printed Newspapers in US This paper looks at the characteristics of the target market that could be the reason, highlights the author’s reasons to believe that this product is declining in appeal, makes recommendations, and discusses a turnaround strategy.
  • The Newspaper Publishing Industry in Australia The fate of newspaper publishing industry across the world and in Australia continues to be unknown. Demographic segmentation enables the industry to succeed in formulating products and services that cater for the needs of customers.
  • Product Repositioning in a Newspaper A research may be carried out to ascertain what percentage of the population still buys a newspaper and the reason for doing that. It is crucial to keep a database of the places to deliver […]
  • Nepean Barrhaven EMC: Newspaper Analysis Reading this issue of the newspaper, it is possible to guess that the editor and the authors of the articles pay special attention to the health of the community.
  • Unemployment, Labor, and Government Economic Forces The article, “The State of Economics”, is an article that discusses the turmoil between economists of the current age in trying to reconcile economic principles with both the classical and Keynesian economic theories of the […]
  • Newspaper Response on Buddhism Finally, the author estimates that harmony is the “essential ingredient” of all religions and it is a guarantee of the welfare of all nations.
  • The Newspaper Critic on Gender Inequalities in Canada Jasmeet Sidhu says in his article in the Star ‘Gender inequality distorts Politics,’ that since Canada elected Agnes MacPhail into the House of Commons in 1921, the country has made major steps in bridging the […]
  • Newspaper Reactions to Brown V. Board of Education It is therefore incorrect to note that the difference in Newspaper reaction to the Brown V. Board of education case was a representation of the difference in opinion between the Southern states and other states.
  • Solution for the Decline of Circulation of Newspaper
  • Goodwill Hunting and Profit Sharing: Decision-Making in a Newspaper Chain
  • Prices and Network Eects in Two-Sided Markets: the Belgian Newspaper Industry
  • The Main Issues Involving the Ownership of The Canadian Newspaper Industry
  • Early Colonial Era Newspaper Accounts of Conflicts, Disease, and Westward Expansion
  • What Effect Does Online News Edition Have on Printed Newspaper
  • Printted Newspaper vs. Online Newspapers
  • The Argument Between the Communitarians and Liberals in the Newspaper Article The American Prospect Online
  • How Internet Affects The Newspaper Business
  • Difference Between Internet Advertising and Newspaper Advertising
  • Predicting Bitcoin Returns: Comparing the Roles of Newspaper- and Internet Search-Based Measures of Uncertainty
  • External Environment Analysis For The Newspaper Industry
  • Newspaper Reading and Relating to the Human Bill of Rights
  • Sensationalism, Newspaper Profits and the Marginal Value of Watergate
  • How the Newspaper and Music Industry Has Changed Because of E-Commerce
  • Various Analysis Tools Applied to The Newspaper Industry
  • Circulations, Revenues, and Profits in a Newspaper Market with Fixed Advertising Costs
  • Uses and Gratification: Nigerian Students Use of Newspaper
  • Damaging Sexual Stereotypes about Women in TV and Newspaper Ads
  • Gender Stereotypes and the Credibility of Newspaper Articles Associated
  • Newspaper Differentiation and Investments in Journalism: The Role of Tax Policy
  • Meet the Press: How Voters and Politicians Respond to Newspaper Entry and Exit
  • Modernism: Newspaper and Miss Representation
  • Media Bias and Influence: Evidence from Newspaper Endorsements
  • Lexical Features Structure Features and Rhetorical Devices of English Newspaper
  • The Newspaper Industry’s Contribution to the Economy
  • Newspaper Reading Habbit Among School Teachers
  • Using Newspaper Magazine Articles Online Databases Strayer Learning Resources
  • Newspaper: How Did the American Newspapers Report on Events Taking Place in Europe During the Holocaust
  • Newspaper Journalism During The Revolutionary War
  • Why The Newspaper Companies Are Suffering From Decline
  • The Real Estate Section of the Local Newspaper
  • The Newspaper Industry and the Changes in the Last 20 Years
  • Legal and Economic Aspects in Theft of Newspapers: Using a Model of Newspaper Value
  • Daily Newspaper Advertising Rates, Local Media Cross-Ownership, Newspaper Chains, and Media Competition
  • The Scotsman and The Guardian: Which Newspaper Is Better
  • Scale Economics, Market Power, and Pricing Behavior Evidence from German Newspaper and Magazine Publishing
  • The Early Twentieth Century’s Immigration and the Newspaper Jobs
  • Utilizing Newspaper Advertise Women Advertisements Society
  • Fracking and Metaphor: Analysing Newspaper Discourse in the USA, Australia and the United Kingdom
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Research Paper Topics

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Choose your Topic Smart

What starts well, ends well, so you need to be really careful with research paper topics. The topic of a research paper defines the whole piece of writing. How often have you chosen the book by its title? First impression is often influential, so make sure your topic will attract the reader instantly. By choosing your topic smart, the half of your job is done. That is why we have singled out several secrets on how to pick the best topic for you. Also see the list of 1000 thesis topics .

Browse Research Paper Topics by Category:

  • Anthropology
  • Argumentative
  • Communication
  • Criminal Justice
  • Environmental
  • Political Science

What is the Key to a Perfect Topic for a Research Paper?

The key to a perfect topic includes three main secrets: interest, precision, and innovation.

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It is impossible to do something great if you have no interest in what you are doing. For this reason, make sure you choose the topic that drives you. If you are bored by what you investigate, do not expect that your paper will be exciting. Right now, spend some minutes or even hours thinking about what interests you. Jot down all your preferences in life, science, politics, social issues etc. It will help you get the idea what you can write about.

After realizing what drives you, narrow this general idea to a more specific one. A research paper is not about beating around the bush. You will need clear facts and data. You will have to provide evidence to your ideas. You will need to be precise, specific and convincing.

Finally, the idea of any research is that it should be surprising and distinctive. Think what makes your perspective and approach special. What is the novelty of your research?

Use Technology

If you are still stuck, use technology. Today we have an opportunity to make our lives easier with a bit of technology used. You can find paper topic generators online. This software will examine the category you want to investigate and the keywords from your research. Within several seconds, this program generates paper topics, so you can try it yourself. It can help you get started with your assignment.

100% Effective Advice

We will now give you advice that is 100% effective when picking the topic. Firstly, forget about what others may think about your topic. This is your topic and this is your perception of the world. Stay personal and let your personal style get you the top grades. Secondly, never decide on the topic before analyzing the background for your research. By this we mean, investigate the topic before you start the research proper. It happens quite often that students choose the topic and later they realize there is no data or information to use. That is why conduct some research beforehand. Thirdly, read other researchers’ papers on the topic you want to write about. It will help you get the idea of the investigation. Moreover, it will help you understand whether you truly want to write a paper on this topic. Finally, when you have picked the topic, started your research, make sure you dedicate your time and energy. If you want to get high results, you need to study every little details of your research.

Examine Different Ideas

People often come up with genius ideas after analyzing thousands of other people’s ideas. This is how our brain works. That is why you can analyze other people’s ideas for research paper topics and think up your own. If you have never written any paper of that kind, it will help you understand the gist of this assignment, the style and the requirements. By comparing different topics, you can motivate yourself and get inspired with these ideas. Luckily, you have come to the right place. Here is our list of top 100 research paper topics.

Top 10 Argumentative Research Paper Topics:

Argumentative research papers examine some controversial issues. Your task is to provide your point of view, your argument, and support your idea with the evidence. This academic assignment requires appropriate structuring and formatting.

  • Does a College Education Pay?
  • Dual Career Families and Working Mothers
  • Electronic Copyright and Piracy
  • Drinking on Campus
  • Education for Homeless Children
  • Glass ceiling
  • Honor System at Colleges
  • Sex and Violence on TV
  • Word Population and Hunger
  • World Trade and Globalization

Top 10 Economics Research Paper Topics:

If you are studying economics, you can find various topics at our site. Check out topics of micro- and macroeconomics. See ideas for urgent economic problems, economic models and strategies. Get inspired and come up with your perfect topic.

  • Beyond Make-or-Buy: Advances in Transaction Cost Economics
  • Economic Aspects of Cultural Heritage
  • Economics of Energy Markets
  • Globalization and Inequality
  • International Trade and Trade Restrictions
  • Aggregate Expenditures Model and Equilibrium Output
  • Taxes Versus Standards
  • Predatory Pricing and Strategic Entry Barriers
  • Marxian and Institutional Industrial Relations in the United States
  • Twentieth-Century Economic Methodology

Top 10 Education Research Paper Topics:

Education has so many questions, and yet few answers. The list of education topic is endless. We have chosen the top 10 topics on the urgent issues in education. You can find ideas related to different approaches, methodology, classroom management, etc.

  • Teachers Thinking About Their Practice
  • Cognitive Approaches to Motivation in Education
  • Responsive Classroom Management
  • Ten Steps to Complex Learning
  • Economics and School-to-Work
  • Reading and Literacy in Adolescence
  • Diversifying the Teaching Force
  • Teacher-Student Relationships
  • Preparing for College and Graduate School
  • Role of Professional Learning

Top 10 History Research Paper Topics:

Choose your topic regarding cultural, economic, environmental, military, political or social history. See what other researchers investigated, compare their ideas and pick the topic that interests you.

  • European Expansion
  • Orientalism
  • Current trends in Historiography
  • Green Revolution
  • Religion and War
  • Women’s Emancipation Movements
  • History of Civilization

Top 10 Psychology Research Paper Topics:

The list of psychology categories and topics is enormous. We have singled out the most popular topics on psychology in 2019. It is mostly topics on modern psychology. Choose the topic the appeals to you the most or ask our professionals to help you come up with some original idea.

  • Imaging Techniques for the Localization of Brain Function
  • Memory and Eyewitness Testimony
  • Traditional Neuroscience Research Methods
  • Meditation and the Relaxation Response
  • Assessment of Mental Health in Older Adults
  • Cross-Cultural Psychology and Research
  • Industrial and Organizational Psychology
  • Diagnostic and Statistical Manual of Mental Disorders
  • Prejudice and Stereotyping
  • Nature Versus Nurture

Top 10 Biology Research Paper Topics:

Here you can find topics related to the science of all forms of life. Examine the topics from different fields in biology and choose the best one for you.

  • Biological Warfare
  • Clone and Cloning
  • Genetic Disorders
  • Genetic Engineering
  • Kangaroos and Wallabies
  • Mendelian Laws of Inheritance
  • Molecular Biology
  • Sexually Transmitted Diseases

Top 10 Chemistry Research Paper Topics:

The best way to understand chemistry is to write a paper on chemistry topic. Below you can see the topics from different fields of chemistry: organic, inorganic, physical, analytical and others.

  • Acids and Bases
  • Alkaline Earth Metals
  • Dyes and Pigments
  • Chemical Warfare
  • Industrial Minerals
  • Photochemistry
  • Soaps and Detergents
  • Transition Elements

Top 10 Physics Research Paper Topics:

Check out the topics on classical and modern physics. Find ideas for writing about interrelationships of physics to other sciences.

  • Aerodynamics
  • Atomic Theory
  • Celestial Mechanics
  • Fluid Dynamics
  • Magnetic recording
  • Microwave Communication
  • Quantum mechanics
  • Subatomic particles

Top 10 Sociology Research Paper Topics:

Find ideas related to different sociological theories, research and methodologies.

  • Feminist Methodologies and Epistemology
  • Quality-of-Life Research
  • Sociology of Men and Masculinity
  • Sociology of Leisure and Recreation
  • Environmental Sociology
  • Teaching and Learning in Sociology
  • The History of Sociology: The North American Perspective
  • The Sociology of Voluntary Associations
  • Marriage and Divorce in the United States
  • Urban Sociology in the 21 st Century

Top 10 Technology Research Paper Topics:

See topics related to the cutting-edge technology or dive into history of electronics, or even early advances in agriculture.

  • Food Preservation: Freeze Drying, Irradiation, and Vacuum Packing
  • Tissue Culturing
  • Digital Telephony
  • Computer-Aided Control Technology
  • Minerals Prospecting
  • Prefabricated Buildings
  • Timber Engineering
  • Quantum Electronic Devices
  • Thermal Water Moderated Nuclear Reactors
  • Long Range Radars and Early Warning Systems

What Makes a Good Topic for a Research Paper?

A good research paper topic is the one that is successful and manageable in your particular case. A successful research paper poses an interesting question you can actually answer. Just as important, it poses a question you can answer within the time available. The question should be one that interests you and deserves exploration. It might be an empirical question or a theoretical puzzle. In some fields, it might be a practical problem or policy issue. Whatever the question is, you need to mark off its boundaries clearly and intelligently so you can complete the research paper and not get lost in the woods. That means your topic should be manageable as well as interesting and important.

A topic is  manageable  if you can:

  • Master the relevant literature
  • Collect and analyze the necessary data
  • Answer the key questions you have posed
  • Do it all within the time available, with the skills you have

A topic is  important  if it:

  • Touches directly on major theoretical issues and debates, or
  • Addresses substantive topics of great interest in your field

Ideally, your topic can do both, engaging theoretical and substantive issues. In elementary education, for example, parents, teachers, scholars, and public officials all debate the effectiveness of charter schools, the impact of vouchers, and the value of different reading programs. A research paper on any of these would resonate within the university and well beyond it. Still, as you approach such topics, you need to limit the scope of your investigation so you can finish your research and writing on time. After all, to be a good research paper, it first has to be a completed one. A successful research paper poses an interesting question you can actually answer within the time available for the project. Some problems are simply too grand, too sweeping to master within the time limits. Some are too minor to interest you or anybody else.

The solution, however, is not to find a lukewarm bowl of porridge, a bland compromise. Nor is it to abandon your interest in larger, more profound issues such as the relationship between school organization and educational achievement or between immigration and poverty. Rather, the solution is to select a well-defined topic that is closely linked to some larger issue and then explore that link. Your research paper will succeed if you nail a well-defined topic. It will rise to excellence if you probe that topic deeply and show how it illuminates wider issues.The best theses deal with important issues, framed in manageable ways. The goal is to select a well-defined topic that is closely linked to some larger issue and can illuminate it.

You can begin your project with either a large issue or a narrowly defined topic, depending on your interests and the ideas you have generated. Whichever way you start, the goals are the same: to connect the two in meaningful ways and to explore your specific topic in depth.

Of course, the choice of a particular research paper topic depends on the course you’re taking. Our site can offer you the following research paper topics and example research papers:

Moving from a Research Paper Idea to a Research Paper Topic

Let’s begin as most students actually do, by going from a “big issue” to a more manageable research paper topic. Suppose you start with a big question such as, “Why has the United States fought so many wars since 1945?” That’s certainly a big, important question. Unfortunately, it’s too complex and sprawling to cover well in a research paper. Working with your professor or instructor, you could zero in on a related but feasible research topic, such as “Why did the Johnson administration choose to escalate the U.S. war in Vietnam?” By choosing this topic, your research paper can focus on a specific war and, within that, on a few crucial years in the mid-1960s.

You can draw on major works covering all aspects of the Vietnam War and the Johnson administration’s decision making. You have access to policy memos that were once stamped top secret. These primary documents have now been declassified, published by the State Department, and made available to research libraries. Many are readily available on the Web. You can also take advantage of top-quality secondary sources (that is, books and articles based on primary documents, interviews, and other research data).

Drawing on these primary and secondary sources, you can uncover and critique the reasons behind U.S. military escalation. As you answer this well-defined question about Vietnam, you can (and you should) return to the larger themes that interest you, namely, “What does the escalation in Southeast Asia tell us about the global projection of U.S. military power since 1945?” As one of America’s largest military engagements since World War II, the war in Vietnam should tell us a great deal about the more general question.

The goal here is to pick a good case to study, one that is compelling in its own right and speaks to the larger issue. It need not be a typical example, but it does need to illuminate the larger question. Some cases are better than others precisely because they illuminate larger issues. That’s why choosing the best cases makes such a difference in your research paper.

Since you are interested in why the United States has fought so often since 1945, you probably shouldn’t focus on U.S. invasions of Grenada, Haiti, or Panama in the past two decades. Why? Because the United States has launched numerous military actions against small, weak states in the Caribbean for more than a century. That is important in its own right, but it doesn’t say much about what has changed so dramatically since 1945. The real change since 1945 is the projection of U.S. power far beyond the Western Hemisphere, to Europe and Asia. You cannot explain this change—or any change, for that matter—by looking at something that remains constant.

In this case, to analyze the larger pattern of U.S. war fighting and the shift it represents, you need to pick examples of distant conflicts, such as Korea, Vietnam, Kosovo, Afghanistan, or Iraq. That’s the noteworthy change since 1945: U.S. military intervention outside the Western Hemisphere. The United States has fought frequently in such areas since World War II but rarely before then. Alternatively, you could use statistics covering many cases of U.S. intervention around the world, perhaps supplemented with some telling cases studies.

Students in the humanities want to explore their own big ideas, and they, too, need to focus their research. In English literature, their big issue might be “masculinity” or, to narrow the range a bit, “masculinity in Jewish American literature.” Important as these issues are, they are too vast for anyone to read all the major novels plus all the relevant criticism and then frame a comprehensive research paper.

If you don’t narrow these sprawling topics and focus your work, you can only skim the surface. Skimming the surface is not what you want to do in a research paper. You want to understand your subject in depth and convey that understanding to your readers.

That does not mean you have to abandon your interest in major themes. It means you have to restrict their scope in sensible ways. To do that, you need to think about which aspects of masculinity really interest you and then find works that deal with them.

You may realize your central concern is how masculinity is defined in response to strong women. That focus would still leave you considerable flexibility, depending on your academic background and what you love to read. That might be anything from a reconsideration of Macbeth to an analysis of early twentieth-century American novels, where men must cope with women in assertive new roles. Perhaps you are interested in another aspect of masculinity: the different ways it is defined within the same culture at the same moment. That would lead you to novelists who explore these differences in their characters, perhaps contrasting men who come from different backgrounds, work in different jobs, or simply differ emotionally. Again, you would have considerable flexibility in choosing specific writers.

Connecting a Specific Research Paper Topic to a Bigger Idea

Not all students begin their research paper concerned with big issues such as masculinity or American wars over the past half century. Some start with very specific topics in mind. One example might be the decision to create NAFTA, the North American Free Trade Agreement encompassing Canada, the United States, and Mexico. Perhaps you are interested in NAFTA because you discussed it in a course, heard about it in a political campaign, or saw its effects firsthand on local workers, companies, and consumers. It intrigues you, and you would like to study it in a research paper. The challenge is to go from this clear-cut subject to a larger theme that will frame your paper.

Why do you even need to figure out a larger theme? Because NAFTA bears on several major topics, and you cannot explore all of them. Your challenge—and your opportunity—is to figure out which one captures your imagination.

One way to think about that is to finish this sentence: “For me, NAFTA is a case of ___________.” If you are mainly interested in negotiations between big and small countries, then your answer is, “For me, NAFTA is a case of a large country like the United States bargaining with a smaller neighbor.” Your answer would be different if you are mainly interested in decision making within the United States, Mexico, or Canada. In that case, you might say, “NAFTA seems to be a case where a strong U.S. president pushed a trade policy through Congress.” Perhaps you are more concerned with the role played by business lobbies. “For me, NAFTA is a case of undue corporate influence over foreign economic policy.” Or you could be interested in the role of trade unions, environmental groups, or public opinion.

The NAFTA decision is related to all these big issues and more. You cannot cover them all. There is not enough time, and even if there were, the resulting paper would be too diffuse, too scattershot. To make an impact, throw a rock, not a handful of pebbles.

Choosing one of these large issues will shape your research paper on NAFTA. If you are interested in U.S. decision making, for example, you might study the lobbying process or perhaps the differences between Democrats and Republicans. If you are interested in diplomacy, you would focus on negotiations between the United States, Canada, and Mexico. Either would make an interesting research paper, but they are different topics.

Although the subject matter and analysis are decidedly different in the humanities, many of the same considerations still apply to topic selection. In English or comparative literature, for example, you may be attracted to a very specific topic such as several poems by William Wordsworth. You are not trying, as a social scientist would, to test some generalizations that apply across time or space. Rather, you want to analyze these specific poems, uncover their multiple meanings, trace their allusions, and understand their form and beauty.

As part of the research paper, however, you may wish to say something bigger, something that goes beyond these particular poems. That might be about Wordsworth’s larger body of work. Are these poems representative or unusual? Do they break with his previous work or anticipate work yet to come? You may wish to comment on Wordsworth’s close ties to his fellow “Lake Poets,” Coleridge and Southey, underscoring some similarities in their work. Do they use language in shared ways? Do they use similar metaphors or explore similar themes? You may even wish to show how these particular poems are properly understood as part of the wider Romantic movement in literature and the arts. Any of these would connect the specific poems to larger themes.

How to Refine Your Research Paper Topic

One of your professor’s or instructor’s most valuable contributions to the success of your research paper is to help you refine your topic. She can help you select the best cases for detailed study or the best data and statistical techniques. S/he can help you find cases that shed light on larger questions, have good data available, and are discussed in a rich secondary literature. She may know valuable troves of documents to explore. That’s why it is so important to bring these issues up in early meetings. These discussions with your instructor are crucial in moving from a big but ill-defined idea to a smart, feasible topic.Some colleges supplement this advising process by offering special workshops and tutorial support for students. These are great resources, and you should take full advantage of them. They can improve your project in at least two ways.

First, tutors and workshop leaders are usually quite adept at helping you focus and shape your topic. That’s what they do best. Even if they are relatively new teachers, they have been writing research papers themselves for many years. They know how to do it well and how to avoid common mistakes. To craft their own papers, they have learned how to narrow their topics, gather data, interpret sources, and evaluate conjectures. They know how to use appropriate methods and how to mine the academic literature. In all these ways, they can assist you with their own hard-won experience. To avoid any confusion, just make sure your instructor knows what advice you are getting from workshop leaders and tutors. You want everyone to be pulling in the same direction.

Second, you will benefit enormously from batting around your research paper in workshops. The more you speak about your subject, the better you will understand it yourself. The better you understand it, the clearer your research and writing will be. You will learn about your project as you present your ideas; you will learn more as you listen to others discuss your work; and you will learn still more as you respond to their suggestions. Although you should do that in sessions with your instructor, you will also profit from doing it in workshops and tutorial sessions.

Secrets to Keep in Mind when Writing a Research Paper

As a bonus, we have prepared several secrets for you to make your paper perfect. Firstly, always write your paper from scratch. Do not copy the already existing materials, as it can lead to unsatisfactory mark or even expulsion. Secondly, start your research early; do not put off investigating the topic. The earlier you start, the easier it will be to meet the deadline. Thirdly, plan your work and create an outline for your task. A planned work will help you be systematic. Plus, it will help you avoid writer’s block, as you always have an outline to follow. Another secret is following all the requirements. A research paper is an academic assignment, so all these structural and formatting standards are important. Finally, make sure you proofread and edit your task. Check your paper for grammar and spelling mistakes, examine your choice of vocabulary. If it seems too much, you can always ask our professional editors and they will check the paper for you. A mistakes-free paper is essential to get high results.

Custom Research Paper Writing Service

If you still have concerns regarding your research paper, we are here to answer your questions. It is no secret that studying is becoming more and more difficult at college. Every week you have an overload of tasks and assignments. You work hard, sleep little. As a result, you can be at the edge of a nervous breakdown trying to finish all the tasks on time. That is why we are here helping thousands of students to study smart.

24/7 you can contact us and order your paper. We never miss the deadline and always provide our clients with a top-notch quality. When you feel that you cannot handle it on your own, a bit of assistance will do no harm. All our writers are experts with years of experience. They are aware of all the subtleties of academic writing and they know all the recent college requirements. You can turn to us for help any time and we will get down to work immediately. From choosing the topic to writing the whole paper – this is what we have to offer. Getting top grades is much easier when the real professionals help you.

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Former U.S. President Donald Trump holds a press conference following the verdict in his hush-money trial at Trump Tower on May 31, 2024 in New York City.

Former President Donald Trump holds a press conference following the verdict in his hush-money trial at Trump Tower on May 31 in New York City. Spencer Platt/Getty Images hide caption

Trump repeats claims — without evidence — that his trial was rigged

May 31, 2024 • Former President Donald Trump reiterated many of claims — without evidence — that his criminal trial was rigged, a day after a New York jury found him guilty of 34 counts of falsifying business records.

Plastic junk? Researchers find tiny particles in men's testicles

Researchers have detected microplastics in human testicles. Volodymyr Zakharov/Getty Images hide caption

Shots - Health News

Plastic junk researchers find tiny particles in men's testicles.

May 22, 2024 • The new study has scientists concerned that microplastics may be contributing to reproductive health issues.

To escape hungry bats, these flying beetles create an ultrasound 'illusion'

Harlan Gough holds a recently collected tiger beetle on a tether. Lawrence Reeves hide caption

To escape hungry bats, these flying beetles create an ultrasound 'illusion'

May 22, 2024 • A study of tiger beetles has found a possible explanation for why they produce ultrasound noises right before an echolocating bat swoops in for the kill.

A sea otter in Monterey Bay with a rock anvil on its belly and a scallop in its forepaws.

A sea otter in Monterey Bay with a rock anvil on its belly and a scallop in its forepaws. Jessica Fujii hide caption

When sea otters lose their favorite foods, they can use tools to go after new ones

May 20, 2024 • Some otters rely on tools to bust open hard-shelled prey items like snails, and a new study suggests this tool use is helping them to survive as their favorite, easier-to-eat foods disappear.

On this unassuming trail near LA, bird watchers see something spectacular

Lauren Hill, a graduate student at Cal State LA, holds a bird at the bird banding site at Bear Divide in the San Gabriel Mountains. Grace Widyatmadja/NPR hide caption

On this unassuming trail near LA, bird watchers see something spectacular

May 13, 2024 • At Bear Divide, just outside Los Angeles, you can see a rare spectacle of nature. This is one of the only places in the western United States where you can see bird migration during daylight hours.

AI gets scientists one step closer to mapping the organized chaos in our cells

The inside of a cell is a complicated orchestration of interactions between molecules. Keith Chambers/Science Photo Library hide caption

AI gets scientists one step closer to mapping the organized chaos in our cells

May 13, 2024 • As artificial intelligence seeps into some realms of society, it rushes into others. One area it's making a big difference is protein science — as in the "building blocks of life," proteins! Producer Berly McCoy talks to host Emily Kwong about the newest advance in protein science: AlphaFold3, an AI program from Google DeepMind. Plus, they talk about the wider field of AI protein science and why researchers hope it will solve a range of problems, from disease to the climate.

NOAA Issues First Severe Geomagnetic Storm Watch Since 2005

NASA's Solar Dynamics Observatory captured this image of a strong solar flare on May 8, 2024. The Wednesday solar flares kicked off the geomagnetic storm happening this weekend. NASA/SDO hide caption

NOAA Issues First Severe Geomagnetic Storm Watch Since 2005

May 10, 2024 • Scientists at the National Oceanic and Atmospheric Administration observed a cluster of sunspots on the surface of the sun this week. With them came solar flares that kicked off a severe geomagnetic storm. That storm is expected to last throughout the weekend as at least five coronal mass ejections — chunks of the sun — are flung out into space, towards Earth! NOAA uses a five point scale to rate these storms, and this weekend's storm is a G4. It's expected to produce auroras as far south as Alabama. To contextualize this storm, we are looking back at the largest solar storm on record: the Carrington Event.

In a decade of drug overdoses, more than 320,000 American children lost a parent

Esther Nesbitt lost two of her children to drug overdoses, and her grandchildren are among more than 320,000 who lost parents in the overdose epidemic. Andrew Lichtenstein/Corbis via Getty Images hide caption

In a decade of drug overdoses, more than 320,000 American children lost a parent

May 8, 2024 • New research documents how many children lost a parent to an opioid or other overdose in the period from 2011 to 2021. Bereaved children face elevated risks to their physical and emotional health.

Largest-ever marine reptile found with help from an 11-year-old girl

This illustration depicts a washed-up Ichthyotitan severnensis carcass on the beach. Sergey Krasovskiy hide caption

Largest-ever marine reptile found with help from an 11-year-old girl

May 6, 2024 • A father and daughter discovered fossil remnants of a giant ichthyosaur that scientists say may have been the largest-known marine reptile to ever swim the seas.

When PTO stands for 'pretend time off': Doctors struggle to take real breaks

A survey shows that doctors have trouble taking full vacations from their high-stress jobs. Even when they do, they often still do work on their time off. Wolfgang Kaehler/LightRocket via Getty Images hide caption

Perspective

When pto stands for 'pretend time off': doctors struggle to take real breaks.

May 4, 2024 • What's a typical vacation activity for doctors? Work. A new study finds that most physicians do work on a typical day off. In this essay, a family doctor considers why that is and why it matters.

'Dance Your Ph.D.' winner on science, art, and embracing his identity

Weliton Menário Costa (center) holds a laptop while surrounded by dancers for his music video, "Kangaroo Time." From left: Faux Née Phish (Caitlin Winter), Holly Hazlewood, and Marina de Andrade. Nic Vevers/ANU hide caption

'Dance Your Ph.D.' winner on science, art, and embracing his identity

May 4, 2024 • Weliton Menário Costa's award-winning music video showcases his research on kangaroo personality and behavior — and offers a celebration of human diversity, too.

Orangutan in the wild applied medicinal plant to heal its own injury, biologists say

Researchers in a rainforest in Indonesia spotted an injury on the face of a male orangutan they named Rakus. They were stunned to watch him treat his wound with a medicinal plant. Armas/Suaq Project hide caption

Orangutan in the wild applied medicinal plant to heal its own injury, biologists say

May 3, 2024 • It is "the first known case of active wound treatment in a wild animal with a medical plant," biologist Isabelle Laumer told NPR. She says the orangutan, called Rakus, is now thriving.

Launching an effective bird flu vaccine quickly could be tough, scientists warn

The federal government says it has taken steps toward developing a vaccine to protect against bird flu should it become a threat to humans. skodonnell/Getty Images hide caption

Launching an effective bird flu vaccine quickly could be tough, scientists warn

May 3, 2024 • Federal health officials say the U.S. has the building blocks to make a vaccine to protect humans from bird flu, if needed. But experts warn we're nowhere near prepared for another pandemic.

For birds, siblinghood can be a matter of life or death

A Nazca booby in the Galápagos Islands incubates eggs with its webbed feet. Wolfgang Kaehler/LightRocket via Getty Images hide caption

The Science of Siblings

For birds, siblinghood can be a matter of life or death.

May 1, 2024 • Some birds kill their siblings soon after hatching. Other birds spend their whole lives with their siblings and will even risk their lives to help each other.

How do you counter misinformation? Critical thinking is step one

Planet Money

How do you counter misinformation critical thinking is step one.

April 30, 2024 • An economic perspective on misinformation

Scientists restore brain cells impaired by a rare genetic disorder

This image shows a brain "assembloid" consisting of two connected brain "organoids." Scientists studying these structures have restored impaired brain cells in Timothy syndrome patients. Pasca lab, Stanford University hide caption

Scientists restore brain cells impaired by a rare genetic disorder

April 30, 2024 • A therapy that restores brain cells impaired by a rare genetic disorder may offer a strategy for treating conditions like autism, epilepsy, and schizophrenia.

Helping women get better sleep by calming the relentless 'to-do lists' in their heads

Katie Krimitsos is among the majority of American women who have trouble getting healthy sleep, according to a new Gallup survey. Krimitsos launched a podcast called Sleep Meditation for Women to offer some help. Natalie Champa Jennings/Natalie Jennings, courtesy of Katie Krimitsos hide caption

Helping women get better sleep by calming the relentless 'to-do lists' in their heads

April 26, 2024 • A recent survey found that Americans' sleep patterns have been getting worse. Adult women under 50 are among the most sleep-deprived demographics.

As bird flu spreads in cows, here are 4 big questions scientists are trying to answer

Bird flu is spreading through U.S. dairy cattle. Scientists say the risk to people is minimal, but open questions remain, including how widespread the outbreak is and how the virus is spreading. DOUGLAS MAGNO/AFP via Getty Images hide caption

As bird flu spreads in cows, here are 4 big questions scientists are trying to answer

April 26, 2024 • Health officials say there's very little risk to humans from the bird flu outbreak among dairy cattle, but there's still much they don't know. Here are four questions scientists are trying to answer.

Animals get stressed during eclipses. But not for the reason you think

A coyote at the Fort Worth Zoo is photographed in the hours leading up to the April 8 total solar eclipse. The Hartstone-Rose Research Lab, NC State hide caption

Animals get stressed during eclipses. But not for the reason you think

April 25, 2024 • After studying various species earlier this month, some scientists now say they understand the origin of animal behavior during solar eclipses.

A woman with failing kidneys receives genetically modified pig organs

Dr. Jeffrey Stern, assistant professor in the Department of Surgery at NYU Grossman School of Medicine, and Dr. Robert Montgomery, director of the NYU Langone Transplant Institute, prepare the gene-edited pig kidney with thymus for transplantation. Joe Carrotta for NYU Langone Health hide caption

A woman with failing kidneys receives genetically modified pig organs

April 24, 2024 • Surgeons transplanted a kidney and thymus gland from a gene-edited pig into a 54-year-old woman in an attempt to extend her life. It's the latest experimental use of animal organs in humans.

Oncologists' meetings with drug reps don't help cancer patients live longer

Drug companies often do one-on-one outreach to doctors. A new study finds these meetings with drug reps lead to more prescriptions for cancer patients, but not longer survival. Chris Hondros/Getty Images hide caption

Oncologists' meetings with drug reps don't help cancer patients live longer

April 22, 2024 • Drug company reps commonly visit doctors to talk about new medications. A team of economists wanted to know if that helps patients live longer. They found that for cancer patients, the answer is no.

UC Logo

Why Use Newspapers?

Finding a specific newspaper, finding articles if you have a citation, finding articles on a topic, finding article full text.

  • Newspapers in the Library Collection
  • Newspaper Websites

Newspaper articles can provide a useful source of information, serving as a primary source of information about historical and current events. Some of the benefits of using newspaper articles as primary sources include:

  • seeing how people viewed an event when it happened;
  • providing multiple points of view about an issue, including a comparison of the United States and international views;
  • permitting researchers to trace the historical development of subjects over time;
  • examining issues in the context of their time (by seeing how stories about an issue relate to other stories, or by examining the type of coverage provided);
  • giving a snapshot of a time period detailing how people lived, and what they purchased, etc. which is helpful for writers, playwrights, historians, etc.

Because newspapers also contain commentaries or retrospective articles about events, they can also serve as a secondary source. (Modified from Why Use Newspapers? - OhioState University)

To find a specific newspaper, try the following:

1. On the library home page in the search box click the Journals tab. Type the newspaper title.

journals search box

The search will return results for titles starting with the words you typed. If you want to search for the exact tile or are not sure of the the complete title, use the E-Journals Search (link below the box). From the drop-down menu you can select "Title contains all words" if you are not sure in what order the words appear in the title or "Title equals" (the latter would be useful for short titles like "Time" or "Times").

newspaper research topics

2. For titles not available online, click "Print Journals" under the search box for journal searches. This will take you to the library catalog. Click on the "Title" tab. Do a catalog TITLE search for the newspaper title. It is useful to limit your search to Periodicals/Serials.

catalog title search filteres to periodicals

Results list may include several entries for different versions of the title and various formats (print, microfilm, and electronic). If you are confused, ask a librarian for help. For your convenience, information about popular newspapers in our collection is provided in this guide.

Library records may include information about current print holdings and microforms, as well as links to online content. Please note that the catalog does NOT have links to ALL newspapers available online, use the e-journals search for this.

recrod screen for a newspaper title

First, determine if the issue of the newspaper is available online.

Method 1 . Search for the article title in quotation marks (and author's name, if the title is common) in the red search box on the home page (under the "Articles" tab).

search box with the Articles tab selected

A successful search will include a link to the article full text.

Summon result screen for a newspaper article

Method 2. Use the E-Journals search to see if the issue you need is available online. This method is more comprehensive, because it will find ALL of library electronic subscriptions. It also helps when a link in Method 1 does not work.

e-journal serch box with a newspaper title entered

In the results list find a database that covers the period when the article of interest was published.

search results for a newspaper title with links to databases

You can click "Look up Article" or go to the database. Most databases will allow you to browse to the volume and issue or search for the article.

If the article is not available online or you need to see the article as it was published with original graphics, do a catalog search for the newspaper title in the library catalog as described above . Important note: search for the newspaper title, NOT the article title.

  • Start with searching Summon . After you enter your search terms and get results, you will be able to refine you search by Content - Newspapers . You may also select a date range for the articles.

Summon search results filtered to newspapers and limited by date

  • Search one of the general newspaper databases . You should also be able to filter your results to newspaper content and specify dates.
  • Many subject guides provide information on newspapers in the discipline.
  • Ask your subject librarian for assistance.

Please note that newspaper databases come in different formats.

Digital archive databases provide scanned reproductions of original newspaper pages (the full-text and any accompanying graphics).

Full-text databases provide the complete text of newspaper articles (but not accompanying graphics).

Index only databases provide citations (references) to newspaper articles. You can use these to identify the publication date and page number details for specific articles.

Therefore you may still need to use digital or traditional microfilms to view the articles you found using an online database.

If you working with newspapers not available online, you may need to use an index, which may be available in print or on a microfilm. Ask for help at the desk or via an online form .

Remember that if we don't have access to an article you can request it through interlibrary loan (ILLiad) .

(Modified from Newspapers & news services: Finding newspaper articles on a topic - University of Wollongong)

  • Next: Newspapers in the Library Collection >>
  • Last Updated: Mar 11, 2024 11:25 AM
  • URL: https://guides.libraries.uc.edu/newspapers

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A Guide to News Research: Where to Find News Articles: Recent News

  • Recent News
  • Post-1980 Coverage
  • Pre-1980 U.S. Coverage
  • Pre-1980 International News
  • Ethnic News
  • Where are the Newspapers?
  • Early U.S. Newspapers
  • Early English Newspapers
  • Caveats about News Sources

Today's News and Recent News

  • Access World News Database. Access funded by the Library . Coverage and format: Current, from roughly the mid-1980s on (start dates vary widely). Over 7,000 newspapers and newswires, including some web-only titles. Mainly plain text, but 100+ titles now available in color PDFs.
  • Factiva Database. Access funded by the Library . Scroll down to the Newsstand: US box on the Factiva home page to browse the last two weeks of the following news sources—every article, plain text (no graphics)— The New York Times , Wall Street Journal (U.S. edition), and Washington Post from the print editions . Articles in the online versions may not be available in Factiva! Use the Search/SearchBuilder menu to query the full database content. Access limited to 10 simultaneous users.
  • Financial Times/FT.com Online website of the Financial Times . Access funded by the Library and the S C Johnson College of Business . Go to the library catalog record and follow the link to set up your free account. All faculty, students, and staff have access.The default edition is the “International Edition.” You can switch to the UK Edition on the ft.com homepage.
  • Global Newsstream Aggregates all the ProQuest Newsstream databases in one searchable interface, including U.S. Newsstream with all regional Newsstreams, Canadian Newsstream, and International Newsstream (Asian, Australian & New Zealand, European, Latin American, and Middle Eastern & African). Current, searchable full-text access to five major U.S. daily newspapers ( Chicago Tribune , Los Angeles Times , New York Times , The Wall Street Journal , and The Washington Post ) is now available in the U.S. Major Dailies database , a subset of Global Newsstream. See more details in the U.S. Major Dailies entry below . Coverage and format: 1980s to date. Plain text.
  • Library PressDisplay aka PressReader.com Database. Access funded by the Library . Full-color, full-text online versions of a few major print newspaper titles, over 700 magazine and news titles from 55 countries. More frequently-used sources are usually displayed first. Use discretion in picking from these news sources; many popular magazines and non-news sources are included. NB: The last 90 days is available with some exceptions ( Chicago Tribune , last 4 days available, for example) .
  • New York Times Online/nytimes.com Cornell undergraduates can sign in here for unlimited, free access to nytimes.com, funded by the Student Assembly. Law School students, faculty, and staff have access funded by the Law Library. New York Times articles can also be accessed online by all Cornell students, faculty and staff via the U.S. Major Dailies database provided by the library.
  • Nexis Uni Database. Access funded by the Library . Over 15,000 sources including newspapers, journals, wire services, newsletters, company reports and SEC filings, case law, government documents, transcripts of broadcasts, and selected reference works. Formerly LexisNexis Academic.
  • ProQuest Digitized Newspapers [PQDN] / ProQuest Recent Newspapers Full coverage for 31 titles (plus five multi-title regional newspaper collections) starting from either 1/1/2008, 1/1/2009, 1/1/2010, or 1/1/2011, and ending "within days of the current issue." . Primarily publisher PDFs backed by full text searching of OCRed text with some searching of publisher's text feed for the newest issues.
  • U.S. Major Dailies A subset of ProQuest's Global Newsstream database. Current, plain-text access back to 1980 for The New York Times , Washington Post , The Wall Street Journal , Los Angeles Times , and Chicago Tribune . Replaces Factiva as the go-to database for access to current and recent articles in these titles
  • U.S. Northeast Newsstream ProQuest. Subscription. Coverage varies by title: 1980s to date. Plain text. About 100 current newspaper titles from Connecticut, Delaware, Massachusetts, Maine, New Hampshire, New Jersey, New York, Pennsylvania, Rhode Island, and Vermont plus additional non-newspaper titles.
  • Wall Street Journal Online/wsj.com Access funded by the Library and the Johnson School . Online website of the Wall Street Journal . Available free to all Cornell faculty, staff, and students . To set up free access, go to https://partner.wsj.com/partner/cornelluniversity and register. Select your account type from the drop-down menu, add a password, and agree to the Privacy Policy. Then click Create and you have access. All faculty, students, and staff at Cornell.
  • Washington Post Online/washingtonpost.com Paywall situation : Free access is limited to a few articles per month for nonsubscribers. Alternative access for current news: Articles from the last 2 weeks in plain text format are on Factiva’s Newsstand: U.S. box on the home page (see the Factiva entry above).
  • World Politics Review [WPR] Access funded by the Library . Continuously updated. Articles provide analysis of trends and events in international affairs. Published entirely online, WPR's original articles are written by a network of analysts, journalists, and scholars. Articles cover diplomacy, military affairs, energy, economics and related subjects.

International Regional News Services:

  • euro|topics A European press review with English, German, and French summaries for 28 European countries. Text is the translated lead paragraph of the article. Some entries link to the full text online in original language and some only to the source news site. The euro|topics Media page links to country-by-country and title-by-title reviews of the European press.
  • MideastWire.com A daily selection of articles from news sources (print, radio and television media) and newsletters appearing in 22 Arab countries, Iran and the Arab Diaspora. English translations from Arabic and Farsi. Added links to current source home page when available.

Permissions Information

If you wish to use or adapt any or all of the content of this Guide go to Cornell Library's Research Guides Use Conditions to review our use permissions and our Creative Commons license.

  • Next: Post-1980 Coverage >>
  • Last Updated: May 23, 2024 2:26 PM
  • URL: https://guides.library.cornell.edu/newsresearch

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X-59 in Flight Over Land

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Carbon Dioxide CO2 Cloud

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newspaper research topics

Medical School Admissions Doctor

Premeds and Emerging Medical Research

Aspiring physician-scientists should bone up on areas such as gene editing, nanotechnology and regenerative medicine.

Zach Grimmett May 14, 2024

1 in 5 U.S. Cancer Patients Join in Medical Research

HealthDay April 3, 2024

CDC: Tuberculosis Cases Increasing

While the U.S. has one of the lowest rates of tuberculosis in the world, researchers found that cases increased 16% from 2022 to 2023.

Cecelia Smith-Schoenwalder March 28, 2024

newspaper research topics

Researchers Find New Way to Curb Asthma Attacks

HealthDay March 26, 2024

Biden to Sign Order Expanding Health Research in Women

HealthDay March 18, 2024

Politics Hasn't Shaken Most Americans' Faith in Science: Study

HealthDay March 12, 2024

Jill Biden Announces $100 Million for Research on Women's Health

HealthDay Feb. 22, 2024

Study Links Living Alone to Depression

New research bound to influence conversations about America’s ‘loneliness epidemic’ suggests living alone could have implications for physical and mental health.

Steven Ross Johnson Feb. 15, 2024

newspaper research topics

Scientists Discover New Way to Fight Estrogen-Fueled Breast Cancer

HealthDay Feb. 14, 2024

Food Insecurity Tied to Early Death

An inability to get adequate food is shaving years off people’s lives in the U.S., a new study suggests.

Steven Ross Johnson Jan. 29, 2024

newspaper research topics

America 2024

newspaper research topics

U.S. News Live

newspaper research topics

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  • View all journals

Chemistry articles from across Nature Portfolio

Chemistry is a branch of science that involves the study of the composition, structure and properties of matter. Often known as the central science, it is a creative discipline chiefly concerned with atomic and molecular structure and its change, for instance through chemical reactions.

newspaper research topics

Chemo-enzymatic synthesis is spot on for ganglioside glycan libraries

By employing chemo-enzymatic techniques, a diverse 65-member ganglioside glycan library has been generated that provides a comprehensive insight into ganglioside-mediated cellular communication.

  • Sabine L. Flitsch
  • Josef Voglmeir

newspaper research topics

Colourful polymers

  • Alison Stoddart

newspaper research topics

Paired electrochemical process for the capture and conversion of CO 2 to ethylene carbonate

Carbon capture and utilization offers a solution to reducing CO 2 emissions, but economic feasibility presents a barrier to adoption. Now, an electrochemical reaction is introduced that integrates H 2 production with CO 2 capture and utilization to produce ethylene carbonate with a high yield in aqueous solution. A techno-economic analysis indicates the economic viability of this strategy.

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Latest Research and Reviews

Unlocking carbene reactivity by metallaphotoredox α-elimination.

  • Benjamin T. Boyle
  • Nathan W. Dow
  • David W. C. MacMillan

newspaper research topics

Development of Pd-immobilized porous polymer catalysts via Bayesian optimization

This study presented the workflow of machine learning-guided optimization of Pd-immobilized porous polymer catalysts. Two independent variables (DVB and 1-decanol content) were involved in polymerization to maximize TOF as target variable in Suzuki–Miyaura coupling reaction. Bayesian optimization was applied for predictive modeling, and the optimized conditions were experimentally validated in subsequent iterations. By applying this workflow, the catalytic activity of immobilized polymer porous catalysts was successfully optimized using machine learning.

  • Xincheng Zhou
  • Hikaru Matsumoto
  • Yoshiko Miura

newspaper research topics

Repurposing of halogenated organic pollutants via alkyl bromide-catalysed transfer chlorination

The presence of halogens in halogenated organic pollutants has negative impacts on the environment; however, they serve as valuable sources for halogenation reactions. Now it has been shown that transfer chlorination reactions enable the repurposing of halogenated organic pollutants for the synthesis of chlorides and bromides.

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LGBTQI+ People and Substance Use

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  • Research has found that sexual and gender minorities, including lesbian, gay, bisexual, transgender, queer, and intersex people (LGBTQI+), have higher rates of substance misuse and substance use disorders than people who identify as heterosexual. People from these groups are also more likely to enter treatment with more severe disorders.
  • People in LGBTQI+ communities can face stressful situations and environments like stigma and discrimination , harassment, and traumatic experiences . Coping with these issues may raise the likelihood of a person having substance use problems.
  • NIDA supports research to help identify the particular challenges that sexual and gender minority people face, to prevent or reduce substance use disorders among these groups, and to promote treatment access and better health outcomes.

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  • Hear the latest approaches in treatment and care from experts in the fields of HIV and SUD in this NIDA video series, “ At the Intersection .”
  • See the Stigma and Discrimination Research Toolkit from the National Institute of Mental Health.

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Dr. Yilai Shu sits at a desk and talks with a young girl sitting on her mother's lap.

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Credit: Eye & ENT Hospital of Fudan University

Clear as a bell

New successful, expanded trial of groundbreaking therapy for genetic deafness suggests it may be available relatively soon

Alvin Powell

Harvard Staff Writer

A toddler in a bright yellow shirt stands unsteadily, grasping the arm of a chair with one hand while playing with a toy on the seat with the other. His father calls from behind, but the child doesn’t react. 

Six weeks later, the same child stands holding onto a table. When his grandfather calls, he spins, nearly toppling over, saved by the older man who reaches over to steady him. The dramatic change, highlighted in two video clips, documents the effectiveness of a new gene therapy for a type of inherited deafness, researchers say. 

The advance was first reported in January after a trial of six children deaf since birth. The children received treatment in one ear, with five of the six gaining the ability to hear. Scientists reported Wednesday they’d expanded the trial to five more children, this time delivering treatment in both ears. All five, ranging in age from 1 to 11 years, were able to hear in both ears, researchers reported in the journal Nature Medicine.

The team reported only minor side effects such as fever and higher white blood cell counts and cholesterol. While those side effects were transitory, the children became responsive to family members’ voices and some spoke their first words in what researchers hope is a permanent fix. Two children danced to music — which requires complex sound processing — and all were able to localize sound and recognize speech in noisy environments.

“I think this gene therapy is a game-changer,” said  Zheng-Yi Chen , associate professor of otolaryngology, head and neck surgery at  Harvard Medical School  and associate scientist at the  Massachusetts Eye and Ear Infirmary’s  Eaton-Peabody Laboratories. “I have no doubt it will become the standard therapy down the road.”

That journey, said Chen, one of the study’s senior authors, may not take long. Further studies are needed to refine the therapy, he said, but it could be ready in as soon as three to five years. 

The work was led by researchers at Mass Eye and Ear and at the Eye and ENT Hospital of Fudan University in Shanghai, where a team led by Yilai Shu, a former postdoctoral fellow in Chen’s lab, conducted the trial beginning in July 2023. The report provides a snapshot of changes after 13 and 26 weeks, though researchers are continuing to follow the subjects. 

Dr. Yilai Shu showing his team work on a microscope.

Yilai Shu’s research team.

“Children’s lives will be profoundly impacted by the therapy,” Shu said. “It provides a paradigm shift in the treatment of hearing impairment.”

More than 5 percent of the global population — 430 million people — have some kind of deafness, a figure that includes 34 million children, according to statistics cited in the paper. About 26 million have been deaf since birth, with about 60 percent of those due to genetic factors. 

The children in both trials suffered from DFNB9, a type of deafness caused by a mutation in the OTOF gene. The mutated gene causes the body to produce a dysfunctional otoferlin protein. Otoferlin is produced by cells in a snail-shaped part of the inner ear called the cochlea, where sound waves are translated into electric signals. 

Those signals are normally transmitted to the nerves and then travel to the brain for interpretation. Otoferlin is important in the handoff of the signal from the cochlea to the nerves. Without it, the signal generated in the ear never makes it to the brain.

Chen said in January that DFNB9 is an attractive target for the therapy because the structures of the ear are intact and the mutated protein can be traced to a single gene that, if repaired, would restore communication between the ear and brain. 

A complication remained, however. The gene that encodes otoferlin is large enough that it doesn’t fit inside the neutered virus that researchers used to transport the corrected gene into the cochlear cells. 

Researchers solved that problem by breaking the gene in two and sending it in two viral packages instead of one. Though the virus inserted the gene into the cochlear cells’ genome in two pieces, it still produced functional versions of the otoferlin protein.

In the current trial involving two ears, Chen said safety of the treatment was an important consideration. Because they used a virus to deliver the therapy, they had to be on guard for the body’s natural immune reaction. To keep that response from derailing the trial, they decided to treat both ears at once. That prevented a situation where, if the injections were given sequentially, an immune response primed by treatment in the first ear could affect the success of the second. Researchers recorded no toxicity and saw no serious adverse reactions.

“This would suggest that maybe there’s some plasticity in the brain in a patient that we could remodel somehow in the future. This opened up a new field for us to explore.” Zheng-Yi Chen

Shu said he was both relieved and happy when results showed children being able to respond to sound cues and speak their first words. As gratifying, however, was the reaction of the children’s parents, who sometimes cried or expressed disbelief at the changes they saw. 

This second trial also revealed an intriguing wrinkle. One participant was 11, an age considered outside the optimal range for language acquisition, thought to be from birth to around 6 or 7, Chen said. After hearing was restored, however, the 11-year-old did begin to use single words. 

“This would suggest that maybe there’s some plasticity in the brain in a patient that we could remodel somehow in the future,” Chen said. “This opened up a new field for us to explore.”

While hearing impairment stems from an array of causes, Chen said there are 150 genes known to play a role in genetic deafness. The vast majority of those could be treated using a similar regimen, he said. With the success of these trials, he added, it may begin to make sense for children who show difficulty hearing to undergo genetic testing at an early age.

“For us it’s a watershed event,” Chen said. “Personally, I have no doubt we’re going to have a new therapy down the road.”

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New group of University scholars join Bouchet Honor Society

Bouchet Honor Society

University of Miami faculty and students celebrate being inducted into the Bouchet Graduate Honor Society.

By Janette Neuwahl Tannen [email protected] 06-06-2024

Ten members of the University of Miami community were honored for their academic achievements and inducted into the distinguished Edward Alexander Bouchet Graduate Honor Society recently at Yale University.

Named after Edward Alexander Bouchet, a physicist who was also the first self-identified African American to earn a doctoral degree in the United States, the society aims to foster a growing number of scholars who exemplify academic and personal excellence in their field, but who also serve as models of scholarship and leadership for students of diverse backgrounds who are often underrepresented in the academy.

Three University faculty members, one postdoctoral fellow, and six University graduate students were inducted into the society, and many participated in the annual Bouchet Conference, where some presented their research.

“We are honored that so many of our own were selected to join this prestigious organization and had a chance to showcase their work this spring,” said Nicole Leeper Piquero , interim dean of the Graduate School. “It is a testament to the diversity and talent we have at the University of Miami, among our faculty, postdocs and graduate students.”

Since the Bouchet Honor Society was founded in 2005, several University faculty members have been recognized, including President Julio Frenk, who was honored with the Bouchet Leadership Medal in 2016. In addition, 44 graduate students have been inducted into the organization. Each year, the University nominates faculty members, students, and postdoctoral fellows who either identify with underrepresented communities, or whose research focuses on underserved communities.

This year’s faculty honorees include:

Ronald L. Jackson II , a professor of communication studies and journalism at the School of Communication , previously served as a faculty member at Penn State University as well as the University of Illinois, where he became head of African American Studies, and then as an associate dean at the College of Media, before heading to the University of Cincinnati to become dean of the McMicken College of Arts and Sciences. An author of 17 books, Jackson’s interdisciplinary research focuses on intercultural communication, racial trauma, cultural identity, social justice, and/or media.  

Yolanda M. Mart í nez-San Miguel is the Marta S. Weeks Chair in Latin American Studies and specializes in Latin American and Caribbean literature as a professor within the Michele Bowman Underwood Department of Modern Languages and Literatures at the College of Arts and Sciences . An author of four books, Martínez-San Miguel teaches classes in literature, Spanish, and gender studies and has been an advocate for diverse and first-generation students and faculty for 30 years.

Nikki Traylor-Knowles is an associate professor of marine biology and ecology at the Rosenstiel School of Marine, Atmospheric, and Earth Science , where she investigates the immune function of corals. Traylor-Knowles has expertise in cell and molecular biology and studies how the physiology of corals responds to heat stress. Traylor-Knowles is also the founder and director of Black Women in Ecology, Evolution, and Marine Science   , a nonprofit organization whose goal is to help support Black women pursuing science professions.

Graduate student honorees:

Khulud Almutairi is a Ph.D. candidate in the School of Nursing and Health Studies . She earned her nursing degree and went on to serve as a clinical nursing instructor in her native Saudi Arabia, before coming to Coral Gables to pursue her graduate degree. Almutairi’s doctoral research focuses on workplace discrimination of Muslim nurses in the United States. She also formed the Digital Nursing Team to create educational videos for nurses in Arabic. Almutairi aspires to become a nursing educator and researcher, and to develop a holistic form of health care tailored to the well-being of the Muslim community.

Shruti Choudhary is a doctoral candidate in the Department of Chemical, Environmental, and Materials Engineering at the College of Engineering . Her research focuses on the development of new aerosol sensors for health and safety in indoor, outdoor, and space environments. Through her research, Choudhary advocates for the safety of health care professionals, firefighters, and astronauts. She is an active member of the University’s interdisciplinary Center for Aerosol Science and Technology and the Firefighter Cancer Initiative , and is currently developing a sensor to detect citrus greening , which is diminishing America’s citrus crops.

Kapiamba Kashala Fabrice is a graduate student in chemical, environmental and materials engineering at the College of Engineering known for his research and commitment to community. His current work focuses on the toxicity of combustion aerosols, including e-cigarette emissions. He is also an intern at Phoenix Tailings, a company exploring environmentally friendly ways to harvest metals and rare earth elements. Fabrice is committed to mentoring the next generation of engineers in an inclusive academic environment.

Padideh Lovan is a postdoctoral associate at the Sylvester Comprehensive Cancer Center and in the School of Nursing and Health Studies. A registered dietitian, Lovan’s research focuses on multilevel influences on cancer risk behaviors, including poor nutrition, physical inactivity, tobacco use, and alcohol consumption in Hispanic youth.

Rachelle Reid is a doctoral student in clinical psychology at the College of Arts and Sciences , focused on elevating the health of marginalized and underserved communities. Her work has focused on Black women living with HIV and has studied the most effective holistic prevention and intervention methods. Her dissertation focuses on mental health outcomes and religious coping among Black women living with HIV as well as burnout among professionals working in the HIV field. Reid’s mission is to use clinical psychology to help the larger society understand communities that have long faced discrimination.

Guerdiana Thelomar is a graduate student pursuing her doctorate in community psychology at the School of Education and Human Development . Her current research focuses on the experiences and well-being of Black women as they navigate educational experiences. Thelomar hopes her work will contribute to creating healthier and more equitable environments for African American students as they navigate higher education.  

Elliot Weinstein is a graduate student in the clinical psychology track at the College of Arts and Sciences with a concentration on behavioral medicine and quantitative psychology. He is a health equity scholar whose research centers on HIV prevention and treatment in marginalized communities, the intersection of aging and HIV, and innovating community engaged research practices.

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Myelination in the brain may be key to ‘learning’ opioid addiction

New research in mice by Stanford Medicine scientists has found that the process of adaptive myelination, which helps the brain learn new skills, can also promote addiction to opioids.

June 5, 2024 - By Nina Bai

myelination addiction

Stanford Medicine research has found that adaptive myelination, the neuronal process by which we improve our skills, can lead to morphine addiction in mice.  Sherry Young and Alex Mit - stock.adobe.com

Our brains, even in adulthood, continually adapt to what we do, strengthening or weakening neural pathways as we practice new skills or abandon old habits. Now, research by Stanford Medicine scientists has found that a particular type of neuroplasticity, known as adaptive myelination, can also contribute to drug addiction.

In adaptive myelination, more active brain circuits gain more myelin — the fatty insulation that allows electrical signals to travel faster and more efficiently through nerve fibers. Learning to juggle or practicing the piano, for example, gradually increases myelination in the brain circuits involved, optimizing for these abilities.

But the same adaptive myelination that is essential to learning, attention and memory has a dark side. In the new study in mice, researchers found that a single dose of morphine was enough to trigger the steps leading to myelination of dopamine-producing neurons — part of the brain’s reward circuitry — spurring the mice to seek out more of the drug. When myelination was blocked, the mice made no effort to find more morphine.

The new findings , published June 5 in  Nature , show how using addictive drugs can drive maladaptive myelination of the brain’s reward circuitry, which in turn reinforces drug-seeking behavior.

Myelin matters

“Myelin development does not complete until we’re in our late 20s or early 30s, which is kind of fascinating,” said  Michelle Monje , MD, PhD, the Milan Gambhir Professor in Pediatric Neuro-Oncology and senior author of the study.

Even after such a protracted developmental period, special cells in the brain called oligodendrocytes continue to generate new myelin in some brain regions.

“What we’ve come to understand over the last decade or so is that myelin, in some parts of the nervous system, is actually plastic and adaptable to experience,” Monje said. “The activity of a neuron can regulate the extent to which its axon is myelinated.”

Michelle Monje

Michelle Monje

Research in neuroplasticity has mostly focused on changes that occur at synapses — where neurons meet and communicate with each other. Adaptive myelination adds a new layer to how our brains learn from experience.

Much of the foundational knowledge about adaptive myelination has come from Monje’s lab. In 2014, her team reported that stimulating the premotor cortex of mice increased the myelination of neurons there and improved limb movement. Subsequent studies by her lab and collaborators have found that mice need adaptive myelination for spatial learning — to navigate a maze, for example, or to remember a threatening situation.

Reward learning

In the new study, Monje’s team wondered whether adaptive myelination was involved in reward learning. The researchers generated a rewarding experience in mice by giving them cocaine or morphine, or by directly stimulating their dopamine-producing neurons using optogenetic techniques.

Within three hours of a single injection of cocaine or morphine or 30 minutes of stimulation, the researchers were surprised to see a proliferation of the specialized stem cells that are destined to become myelin-producing oligodendrocytes. The proliferation was isolated to a brain region known as the ventral tegmental area, which is involved in reward learning and addiction.

“We didn’t think one dose of morphine or cocaine would do anything,” said  Belgin Yalcin , PhD, lead author of the new study and an instructor in neurology and neurological sciences. “But within three hours there was a change. A very mild change, but still a change.”

Both the speed and specificity of the changes were unexpected, the researchers said.

When researchers repeated the drug injections or brain stimulation for several days, then examined the mice a month later, they indeed found more oligodendrocytes and more myelinated dopamine-producing cells, with thicker myelin around their axons, again only in the ventral tegmental area.

Even a slight thickening of myelin — in this case, by several hundred nanometers — can affect brain function and behavior.

“Details matter in terms of myelin plasticity,” Yalcin said. “So little can make such a big difference in conduction velocity and the synchronicity of the circuit.”

Potent rewards

To see how the myelination translated into behavior, the researchers placed each mouse in a box where it could move freely between two chambers. In one chamber, the mice received a daily injection of morphine. (The researchers decided to focus on morphine because of its relevance to the opioid epidemic.) After five days, the mice strongly preferred the chamber where they had received the drug and would linger there, hoping for another hit.

Belgin Yalcin

Belgin Yalcin

The morphine stimulated the mice’s reward circuitry (specifically, the dopamine-producing neurons in the ventral tegmental area), increased the myelination of these neurons and tuned their brains for further reward-seeking behavior.

Curiously, when the researchers tested a food reward instead of morphine, the mice did not develop more food-seeking behavior, perhaps because the reward was less potent, the researchers said.

“You might not want your reward circuits to be modified by everyday kinds of rewards,” Monje said.

From mice to men

“In the healthy nervous system, adaptive myelination tunes circuit dynamics in a way that supports healthy cognitive functions like learning, memory and attention,” Monje said.

But as the new study demonstrates, the process can go awry, enhancing circuits that drive unhealthy behaviors or failing to enhance circuits required for healthy brain function.

In 2022, Monje’s lab reported that adaptive myelination could explain why some epileptic seizures  worsen  over time. The experience of seizures drives more myelination of the circuits involved, allowing faster and more synchronized signaling, which become more frequent and severe seizures. Her team also has found that reduced myelin plasticity  contributes  to “chemo-fog,” the cognitive impairments that often follow cancer treatment.

In the new study, the precise biochemical steps by which a drug reward leads to myelination are not completely clear. The researchers tried bathing oligodendrocyte precursor cells in dishes of morphine or dopamine and determined that neither chemical directly causes proliferation of these cells.

“A future direction would be to understand what exactly these myelin-forming cells are responding to that comes from the activity of dopaminergic neurons,” Yalcin said.

They found that a pathway known as BDNF-TrkB signaling is part of the story. When they blocked this pathway, the mice did not generate new oligodendrocytes and did not acquire a preference for the chamber where they received the drug. 

“The mice just couldn’t learn where they received their morphine reward,” Monje said.

Ultimately, a better understanding of adaptive myelination might reveal new strategies to help people recover from opioid addiction. Perhaps the process can be reversed and an addiction unlearned.

“We don’t know whether these changes are permanent, but there’s reason to believe that they would not be,” Monje said. “We think that myelin plasticity is bidirectional — you can both increase myelination of a circuit and decrease myelination of a circuit.”

The study was supported by funding from the Gatsby Charitable Foundation, the Wu Tsai Neurosciences Institute NeuroChoice Initiative, the National Institute of Neurological Disorders and Stroke (grant R01NS092597), the NIH Director’s Pioneer Award (DP1NS111132), the National Institute for Drug Abuse (P50DA042012, T32DA035165 and K99DA056573), the National Cancer Institute (P50CA165962, R01CA258384 and U19CA264504), the Robert J. Kleberg, Jr. and Helen C. Kleberg Foundation, Cancer Grand Challenges and Cancer Research UK, a Maternal and Child Health Research Institute at Stanford University Postdoctoral Award, and a Dean’s Postdoctoral Fellowship at Stanford University.

Nina Bai

About Stanford Medicine

Stanford Medicine is an integrated academic health system comprising the Stanford School of Medicine and adult and pediatric health care delivery systems. Together, they harness the full potential of biomedicine through collaborative research, education and clinical care for patients. For more information, please visit med.stanford.edu .

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USF picked as HQ for international virus, pandemic research network

  • Divya Kumar Times staff

The University of South Florida will be the new headquarters of the Global Virus Network, a coalition of more than 80 virology research centers in 40 countries, as well as home to its co-founder, Robert Gallo, who is credited as one of the co-discoverers of HIV.

At an event announcing the partnership Wednesday, Charles Lockwood, executive vice president for USF Health, said he saw the partnership as a way to “expand the role of the university in solving some of society’s most pressing health issues.”

The five-year agreement signed Wednesday states that USF will pay the network $2 million per year for operational and programming support, and provide building and office space.

Lockwood said the partnership would “dramatically increase our ability to collaborate with experts” as well as host seminars, conferences and translate research to practical applications. The Global Virus Network also focuses on public health education and solutions.

Joining Gallo — who is among the most cited scientists in the world with more than 1,300 publications — will be three research development companies and more virologists. Lockwood saw it as an opportunity to build out a medical district in Channelside — which already includes USF’s Heart Institute, College of Medicine, College of Pharmacy and a Tampa General Hospital clinic — and create a “research triangle” of sorts between Moffitt, the main USF campus and the medical campus downtown.

“We think it will become a really dominant force in the world to combat pandemics to foreign disease,” he said.

Brett Giroir, executive chair of the network’s board, said he volunteered to serve on the board after his time as assistant secretary of health and acting Food and Drug Administration commissioner under former President Donald Trump.

“I understand the critically important role that the GVN can play in national policy in global science and keeping the world bio-safe,” he said. “We are interested in health care and public health innovations and practical implementations that help people today, tomorrow, our children and of course those in the future.”

Giroir said he worked with Florida officials on a daily basis during his time with the Trump administration, and said it was a collaborative partnership.

Though Lockwood and USF’s health team were involved in the governor’s response, with the governor appearing near Lockwood to roll out vaccines, Florida’s surgeon general Joseph Ladapo has since called for an end to mRNA vaccines, and Gov. Ron DeSantis has banned vaccine or mask mandates in schools.

The network’s president, Yale-based pediatrician Sten Vermund, said they were aware USF is a state-funded school in Florida, but that the network, registered in Delaware, was independent.

“We will be independent voices for science,” he said.

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That said, Vermund said it’s important to acknowledge not everything about virology and vaccinology is known.

“We will welcome debate and discussion, other points of view being expressed,” he said. “We will take those into account, and we will give our point of view, but we are not afraid of open debate and discussion.”

He added that vaccines have been “a great gift” as a pediatrician.

“We’ve been able to knock down disease incidence and mortality for many vaccine-preventable diseases by 99.99% in our country, but one has to acknowledge that vaccines have side effects,” Vermund said. “One needs a thoughtful cost benefit analysis and needs to work with the FDA and vaccine manufacturers to make vaccines as safe and effective as they could possibly be.”

Gallo is expected to start in July.

He will develop and lead a center for virology at USF and serve as program leader for Infectious Agents and Oncogenesis at the Tampa General Hospital Cancer Institute, senior scientific advisor to the USF Microbiomes Institute and senior scientific advisor to the Office of the Director of the TGH Cancer Institute.

Gallo is celebrated for his early-’80s work that established HIV as a cause for AIDS, and in the decades since has helped develop new HIV testing and treatment procedures. He is also credited with the discovery of retroviruses and their association with cancer.

Editors note: A previous version of this story misspelled Sten Vermund’s name and gave an incorrect title to Charles Lockwood. The story has been corrected.

Divya Kumar is the higher education reporter. Reach her at [email protected].

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Physicists create five-lane superhighway for electrons

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MIT physicists and colleagues have created a five-lane superhighway for electrons that could allow ultra-efficient electronics and more. 

The work, reported in the May 10 issue of Science , is one of several important discoveries by the same team over the past year involving a material that is a unique form of graphene .

“This discovery has direct implications for low-power electronic devices because no energy is lost during the propagation of electrons, which is not the case in regular materials where the electrons are scattered,” says Long Ju, an assistant professor in the Department of Physics and corresponding author of the Science paper.

The phenomenon is akin to cars traveling down an open turnpike as opposed to those moving through neighborhoods. The neighborhood cars can be stopped or slowed by other drivers making abrupt stops or U-turns that disrupt an otherwise smooth commute.

A new material

The material behind this work, known as rhombohedral pentalayer graphene, was discovered two years ago by physicists led by Ju. “We found a goldmine, and every scoop is revealing something new,” says Ju, who is also affiliated with MIT’s Materials Research Laboratory.

In a Nature Nanotechnology paper last October, Ju and colleagues reported the discovery of three important properties arising from rhombohedral graphene. For example, they showed that it could be topological, or allow the unimpeded movement of electrons around the edge of the material but not through the middle. That resulted in a superhighway, but required the application of a large magnetic field some tens of thousands times stronger than the Earth’s magnetic field.

In the current work, the team reports creating the superhighway without any magnetic field.

Tonghang Han, an MIT graduate student in physics, is a co-first author of the paper. “We are not the first to discover this general phenomenon, but we did so in a very different system. And compared to previous systems, ours is simpler and also supports more electron channels.” Explains Ju, “other materials can only support one lane of traffic on the edge of the material. We suddenly bumped it up to five.”

Additional co-first authors of the paper who contributed equally to the work are Zhengguang Lu and Yuxuan Yao. Lu is a postdoc in the Materials Research Laboratory. Yao conducted the work as a visiting undergraduate student from Tsinghua University. Other authors are MIT professor of physics Liang Fu; Jixiang Yang and Junseok Seo, both MIT graduate students in physics; Chiho Yoon and Fan Zhang of the University of Texas at Dallas; and Kenji Watanabe and Takashi Taniguchi of the National Institute for Materials Science in Japan.

How it works

Graphite, the primary component of pencil lead, is composed of many layers of graphene, a single layer of carbon atoms arranged in hexagons resembling a honeycomb structure. Rhombohedral graphene is composed of five layers of graphene stacked in a specific overlapping order.

Ju and colleagues isolated rhombohedral graphene thanks to a novel microscope Ju built at MIT in 2021 that can quickly and relatively inexpensively determine a variety of important characteristics of a material at the nanoscale. Pentalayer rhombohedral stacked graphene is only a few billionths of a meter thick.

In the current work, the team tinkered with the original system, adding a layer of tungsten disulfide (WS 2 ). “The interaction between the WS 2  and the pentalayer rhombohedral graphene resulted in this five-lane superhighway that operates at zero magnetic field,” says Ju.

Comparison to superconductivity

The phenomenon that the Ju group discovered in rhombohedral graphene that allows electrons to travel with no resistance at zero magnetic field is known as the quantum anomalous Hall effect. Most people are more familiar with superconductivity, a completely different phenomenon that does the same thing but happens in very different materials.

Ju notes that although superconductors were discovered in the 1910s, it took some 100 years of research to coax the system to work at the higher temperatures necessary for applications. “And the world record is still well below room temperature,” he notes.

Similarly, the rhombohedral graphene superhighway currently operates at about 2 kelvins, or -456 degrees Fahrenheit. “It will take a lot of effort to elevate the temperature, but as physicists, our job is to provide the insight; a different way for realizing this [phenomenon],” Ju says.

Very exciting

The discoveries involving rhombohedral graphene came as a result of painstaking research that wasn’t guaranteed to work. “We tried many recipes over many months,” says Han, “so it was very exciting when we cooled the system to a very low temperature and [a five-lane superhighway operating at zero magnetic field] just popped out.”

Says Ju, “it’s very exciting to be the first to discover a phenomenon in a new system, especially in a material that we uncovered.”

This work was supported by a Sloan Fellowship; the U.S. National Science Foundation; the U.S. Office of the Under Secretary of Defense for Research and Engineering; the Japan Society for the Promotion of Science KAKENHI; and the World Premier International Research Initiative of Japan.

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For the first time ever, researchers at MIT have observed electrons form “fractional quasiparticles without enabling the influence of a magnetic field,” reports Daniel Garisto for Quanta Magazine.  This discovery “may carry the seeds of long-sought quasiparticles with stable memories that could underpin a new and powerful approach to quantum computing.” 

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