diabetes type 1 evolve case study

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Case Report

Newly diagnosed type 1 diabetes complicated by ketoacidosis and peripheral thrombosis leading to transfemoral amputation, line bisgaard jørgensen.

1 Department of Medical Endocrinology, Odense University Hospital (OUH), Odense C, Denmark

2 Department of Orthopaedic Surgery, Odense University Hospital (OUH),, Odense C, Denmark

Knud Yderstræde

Peripheral vascular thromboembolism is a rarely described complication of diabetic ketoacidosis. We report a 41-year-old otherwise healthy man admitted with ketoacidosis and ischaemia of the left foot. The patient was unsuccessfully treated with thromboendarterectomy, and the extremity was ultimately amputated. The patient had no family history of cardiovascular disease, and all blood sample analyses for hypercoagulability were negative. We recommend an increased focus on peripheral thromboembolism, when treating patients with severe ketoacidosis.

Diabetes mellitus is associated with an increased incidence of thromboembolic complications. In type 2 diabetes mellitus there is clear evidence of thrombophilia partly explained by an increased level of plasminogen activator inhibitor . 1 It is not certain whether there is an increased risk of peripheral vascular thrombosis/embolism in patients with diabetic ketoacidosis. We present a case of diabetic ketoacidosis in a newly diagnosed individual with type 1 diabetes complicated by peripheral vascular insufficiency.

Case presentation

A 41-year-old man was admitted to hospital in a serious medical condition. Besides a history of herniated lumbar disc the patient was healthy. The patient had no history of hypertension, but blood pressure was 156/111 mmHg on admission. During the stay in hospital blood pressure stabilised at around 135/80 mmHg. There was no family history of cardiovascular disease. A few days before admission the patient had episodes of nausea, vomiting and abdominal pain. Additionally, he had polyuria and polydipsia. A few hours before admission, the patient reported acute pain in his left foot and was found to have a pulseless foot without vital signs. On admission an arterial blood gas showed metabolic acidosis (pH 7.02, base excess 24.6 , blood glucose 26 mmol/L) and blood ketones (acetone, acetoacetic acid and β-hydroxybutyric acid) were 6.6 mmol/L.

Investigations

The patient was diagnosed with type 1 diabetes mellitus supported by a low C peptide level of 43 (370–1470 pmol/L) and an antiglutamic acid decarboxylase (GAD) antibody titre of 4.7 (ref. 0–1.0). The complete blood count showed high white cell count of 20.9×10 9 /L but normal haemoglobin level of 8.4 mmol/L and platelet count of 199×10 9 /L. C reactive protein was below 1.0. Screening for a diversity of systemic inflammatory disorders including vasculitis and systemic lupus erythematosus (eg, antinuclear antibodies, antineutrophil cytoplasmic antibodies, lupus anticoagulant and cardiolipin antibodies) were all negative. Protein S and C levels were normal, antithrombin III level was reduced and the coagulation factors were increased (factor II, VII and X were 1.40 units (0.70–1.30) and factor VIII was 3.89 (0.60–1.30)). APTT (activated partial thromboplastin time) was prolonged to 46 s (27–40). Blood lipids were normal with total cholesterol 2.6 mmol/L, LDL-cholesterol 1.5 mmol/L, HDL-cholesterol 0.8 mmol/L and triglycerides 0.72 mmol/L. The ECG showed sinus rhythm without ischaemia, and an echocardiogram also was found normal. A duplex ultrasonography of the lower limbs showed no blood flow in the arteries of the left crus and foot.

Differential diagnosis

Buerger's disease, which is caused by inflammation of the arterial wall, is a relevant differential diagnosis. It mostly appears in smoking men between 20 and 40 years of age, corresponding to the individual in this case who reported smoking 10 cigarettes daily. However, symptoms are mostly less acute in Buerger's disease and the vascular surgeons found no evidence for this condition.

The patient was treated according to the guidelines for management of diabetic ketoacidosis and subsequently referred to a university hospital. Vascular surgery was performed including thromboendarterectomy in several large arteries in the left leg and medication to provide fibrinolysis was injected in the small arteries in the foot, which were too peripherally located to be accessible to surgery. But sufficient blood flow was not obtained due to peripheral thrombosis, and a below-knee amputation was performed. The amputation related wound did not heal after 1 week of observation, and eventually a transfemoral amputation was performed.

Only a few case reports on diabetic ketoacidosis complicated by thrombosis are present in the literature. The fibrinolytic system is disturbed in conditions of metabolic acidosis. Carl et al 2 described the haemolytic factors during diabetic ketoacidosis. They found decreased activity of proteins S and C, which are some of the most important inhibitors of the coagulation process. They also found increased activity of von Willebrand factor, which facilitates platelet adhesion. 3

Thus, it can be speculated that there is an increased risk of venous and arterial thrombosis and atheromatous plaques are prevailing, related to endothelial factors. In the case report presented here, the coagulation factors were affected in a way which indicated increased activity. Proteins S and C were normal, however, they were analysed 36 h after the initial treatment for ketoacidosis. The level of antithrombin III was reduced, probably related to the use of heparin.

Zipser et al 4 described a similar case report of a newly diagnosed individual with diabetes with ketoacidosis and acute aortoiliac and femoral artery occlusion. The patient was also amputated below the knee, but had a fatal outcome. Lin et al 5 describe a case report of ketoacidosis complicated by acute brachial artery thrombosis in a patient with a diabetes duration of 4 years. The brachial artery was rescued by surgical thrombectomy. Insufficiently regulated diabetes can also cause dyslipidemia with increased risk of atheroma formation and embolism arising from vascular endothelium with disintegrated morphology. Congenital hyperlipidaemia has been described to cause coronary artery disease and acute myocardial infarction in children. 6

In the case report presented here, the patient was newly diagnosed with diabetes with a short duration of symptoms of the disease. The patient had no history of thromboembolism and an echocardiogram could not identify any cardiac source of the embolism. The patient had sinus rhythm but it cannot conclusively exclude the likelihood of a transient arrhythmia precipitated by ketoacidosis, which could have caused the embolism. 7 The patient was not influenced by any intercurrent disease, but he was dehydrated because of vomiting during a couple of days. Dehydration in combination with diabetic ketoacidosis increases venous stasis and thereby the risk of deep venous thrombosis according to Virchow's triad. However, it has not been shown to be an independent variable as a cause of venous thrombosis. 5

The marked peripheral vascular changes resulted in significant oedema of the affected extremity, and even though compartment syndrome was excluded, it was not possible to achieve adequate healing. Abrupt onset of peripheral ischaemic symptoms without any history of claudication mitigated the possibility of Buerger's disease.

We present a case of diabetic ketoacidosis complicated by peripheral thromboembolism, which is a rare complication of diabetic ketoacidosis but can have devastating consequences with limb amputation or even death. We recommend an increased focus on peripheral thromboembolism, including assessment of pulse and general signs of peripheral vascular insufficiency (eg, pallor, pain and coldness), when treating patients with severe ketoacidosis. However, other causes of thromboembolism should be excluded before establishing diabetic ketoacidosis as the cause.

Learning points

• Diabetic ketoacidosis can promote a prothrombotic state.
• Peripheral thrombosis/embolism is a rarely described complication of diabetic ketoacidosis, and can have a devastating consequence with limb amputation or death.
• Other causes of thrombosis including cardiac source, thrombophilia, dyslipidemia should be excluded before determining diabetic ketoacidosis as a causative agent.

Contributors: LBJ was involved in the concept and design, literature search and drafting the article. KY was involved in the management of the patient, concept and design, drafting and critical review. OS participated in the management of the patient, reviewed and edited the article.

Competing interests: None.

Patient consent: Obtained.

Provenance and peer review: Not commissioned; externally peer reviewed.

Diabetes Case Studies : Real Problems, Practical Solutions

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Diabetes Case Studies : Real Problems, Practical Solutions Edited by: Boris Draznin, MD, PhD, Cecilia C. Low Wang, MD, FACP, Daniel J. Rubin, MD, MSc, FACE https://doi.org/10.2337/9781580405713 ISBN (print): 978-1-58040-571-3 Publisher: American Diabetes Association

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Table of Contents

• Notes Open the PDF Link PDF for Notes in another window
• Preface Open the PDF Link PDF for Preface in another window
• Introduction Open the PDF Link PDF for Introduction in another window
• Case 1: Maturity-Onset Diabetes of the Young (MODY) as a Diagnostic Possibility By Suzi Kochar, MD ; Suzi Kochar, MD 1 Endocrinology Division, Department of Medicine, Rosalind Franklin University of Medicine and Science/Chicago Medical School, North Chicago, IL. 2 Endocrinology Section, Department of Medicine, Captain James A. Lovell Health Care Center, North Chicago, IL. Search for other works by this author on: This Site PubMed Google Scholar Janice L. Gilden, MS, MD, FCP, FACE Janice L. Gilden, MS, MD, FCP, FACE 1 Endocrinology Division, Department of Medicine, Rosalind Franklin University of Medicine and Science/Chicago Medical School, North Chicago, IL. 2 Endocrinology Section, Department of Medicine, Captain James A. Lovell Health Care Center, North Chicago, IL. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.01 Open the PDF Link PDF for Case 1: Maturity-Onset Diabetes of the Young (MODY) as a Diagnostic Possibility in another window
• Case 2: Diagnosis of Coexistent Maturity-Onset Diabetes of the Young in a Patient with Type 1 Diabetes By Shazli Azmi, MBChB ; Shazli Azmi, MBChB 1 Institute of Human Development, Center for Endocrinology and Diabetes, University of Manchester. 2 Department of Medicine and Manchester Diabetes Center, University of Manchester and Central Manchester NHS Foundation Trust. Search for other works by this author on: This Site PubMed Google Scholar Rayaz A. Malik, MBChB, PhD Rayaz A. Malik, MBChB, PhD 1 Institute of Human Development, Center for Endocrinology and Diabetes, University of Manchester. 2 Department of Medicine and Manchester Diabetes Center, University of Manchester and Central Manchester NHS Foundation Trust. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.02 Open the PDF Link PDF for Case 2: Diagnosis of Coexistent Maturity-Onset Diabetes of the Young in a Patient with Type 1 Diabetes in another window
• Case 3: An Unusual Clinical Presentation of Diabetes Eventually Diagnosed as a Monogenic Form By Vince N. Montes, MD ; Vince N. Montes, MD 1 University of Washington, Division of Metabolism, Endocrinology, and Nutrition, Seattle, WA. Search for other works by this author on: This Site PubMed Google Scholar Alan Chait, MD ; Alan Chait, MD 1 University of Washington, Division of Metabolism, Endocrinology, and Nutrition, Seattle, WA. Search for other works by this author on: This Site PubMed Google Scholar Craig E. Taplin, MD Craig E. Taplin, MD 2 Department of Pediatrics, University of Washington, Seattle Children’s Hospital, Division of Endocrinology and Diabetes, Seattle, WA. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.03 Open the PDF Link PDF for Case 3: An Unusual Clinical Presentation of Diabetes Eventually Diagnosed as a Monogenic Form in another window
• Case 4: A Case of Monogenic Diabetes By Robert H. Slover, MD Robert H. Slover, MD 1 Professor of Pediatrics, University of Colorado School of Medicine, Denver, CO; Director of Pediatrics, Barbara Davis Center for Childhood Diabetes; Wagner Family Chair in Childhood Diabetes. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.04 Open the PDF Link PDF for Case 4: A Case of Monogenic Diabetes in another window
• Case 5: Recurrent Ketoacidosis: Lessons from Multiple Clinical Presentations By Eli Ipp, MD ; Eli Ipp, MD 1 Division of Endocrinology, Los Angeles Biomedical Research Institute at Harbor–UCLA Medical Center, Los Angeles, CA. Search for other works by this author on: This Site PubMed Google Scholar Kristina Djekic, MS Kristina Djekic, MS 1 Division of Endocrinology, Los Angeles Biomedical Research Institute at Harbor–UCLA Medical Center, Los Angeles, CA. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.05 Open the PDF Link PDF for Case 5: Recurrent Ketoacidosis: Lessons from Multiple Clinical Presentations in another window
• Case 6: Ketoacidosis in a Patient with Type 1 Diabetes on a Low-Calorie Meal Replacement Diet By Katy Brown, DO ; Katy Brown, DO 1 Fellow in Endocrinology, University of Colorado, School of Medicine, Denver, CO. Search for other works by this author on: This Site PubMed Google Scholar Daniel Bessesen, MD Daniel Bessesen, MD 2 University of Colorado, School of Medicine, Chief of Endocrinology, Denver Health Medical Center, Denver, CO. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.06 Open the PDF Link PDF for Case 6: Ketoacidosis in a Patient with Type 1 Diabetes on a Low-Calorie Meal Replacement Diet in another window
• Case 7: Reevaluation after Ketoacidosis Presentation By Paulina Cruz-Bravo, MD ; Paulina Cruz-Bravo, MD 1 Fellowship in Endocrinology, Diabetes and Metabolism, Division of Endocrinology, Metabolism and Lipid Research, Washington University School of Medicine, St. Louis, MO. Search for other works by this author on: This Site PubMed Google Scholar Janet B. McGill, MD Janet B. McGill, MD 1 Fellowship in Endocrinology, Diabetes and Metabolism, Division of Endocrinology, Metabolism and Lipid Research, Washington University School of Medicine, St. Louis, MO. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.07 Open the PDF Link PDF for Case 7: Reevaluation after Ketoacidosis Presentation in another window
• Case 8: Metabolic Syndrome-Related Comorbidities Typical of Older Adulthood Complicate Diabetic Ketoacidosis in a Youth with Type 2 Diabetes By Kristen Nadeau, MD, MS Kristen Nadeau, MD, MS 1 University of Colorado Denver/Children’s Hospital Colorado, Aurora, CO. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.08 Open the PDF Link PDF for Case 8: Metabolic Syndrome-Related Comorbidities Typical of Older Adulthood Complicate Diabetic Ketoacidosis in a Youth with Type 2 Diabetes in another window
• Case 9: Not Your Usual Diabetic Ketoacidosis By Ruchi Gaba, MD ; Ruchi Gaba, MD 1 Division of Endocrinology Diabetes and Metabolism, Baylor College of Medicine, Houston, TX. Search for other works by this author on: This Site PubMed Google Scholar Susan L. Samson, MD, PhD ; Susan L. Samson, MD, PhD 2 Department of Medicine, Baylor College of Medicine, Houston, TX. Search for other works by this author on: This Site PubMed Google Scholar Alan J. Garber, MD, PhD, FACE Alan J. Garber, MD, PhD, FACE 3 Departments of Medicine, Molecular and Cellular Biology, Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.09 Open the PDF Link PDF for Case 9: Not Your Usual Diabetic Ketoacidosis in another window
• Case 10: Ketosis-Prone Diabetes By David Saxon, MD ; David Saxon, MD 1 Division of Endocrinology, Diabetes and Metabolism, University of Colorado, Aurora CO. Search for other works by this author on: This Site PubMed Google Scholar Neda Rasouli, MD Neda Rasouli, MD 1 Division of Endocrinology, Diabetes and Metabolism, University of Colorado, Aurora CO. 2 Denver Veterans Affairs Medical Center, Denver CO. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.10 Open the PDF Link PDF for Case 10: Ketosis-Prone Diabetes in another window
• Case 11: From a Total Daily Dose of Insulin of 415 Units to No Insulin: A Case of Ketosis-Prone Diabetes By Caroline T. Nguyen, MD ; Caroline T. Nguyen, MD 1 Keck School of Medicine, Division of Endocrinology, Diabetes, and Metabolism, University of Southern California, Los Angeles, CA. Search for other works by this author on: This Site PubMed Google Scholar Jorge H. Mestman, MD Jorge H. Mestman, MD 1 Keck School of Medicine, Division of Endocrinology, Diabetes, and Metabolism, University of Southern California, Los Angeles, CA. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.11 Open the PDF Link PDF for Case 11: From a Total Daily Dose of Insulin of 415 Units to No Insulin: A Case of Ketosis-Prone Diabetes in another window
• Case 12: The Worst Case Scenario: Severe HHS in a Relatively Young Man By Elizabeth Herman, MD ; Elizabeth Herman, MD 1 Boston University School of Medicine, Section of Endocrinology, Diabetes, Nutrition and Weight Management, Boston MA. Search for other works by this author on: This Site PubMed Google Scholar Marie E. McDonnell, MD Marie E. McDonnell, MD 1 Boston University School of Medicine, Section of Endocrinology, Diabetes, Nutrition and Weight Management, Boston MA. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.12 Open the PDF Link PDF for Case 12: The Worst Case Scenario: Severe HHS in a Relatively Young Man in another window
• Case 13: Unusual Cause of New-Onset Diabetes By Kelsey M. Shikuma, MD ; Kelsey M. Shikuma, MD 1 Keck School of Medicine, Division of Endocrinology, Diabetes and Metabolism, University of Southern California, Los Angeles, CA. Search for other works by this author on: This Site PubMed Google Scholar Jorge H. Mestman, MD Jorge H. Mestman, MD 1 Keck School of Medicine, Division of Endocrinology, Diabetes and Metabolism, University of Southern California, Los Angeles, CA. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.13 Open the PDF Link PDF for Case 13: Unusual Cause of New-Onset Diabetes in another window
• Case 14: What Type of Diabetes? By Anthony L. McCall, PhD, FACP Anthony L. McCall, PhD, FACP 1 University of Virginia School of Medicine and Health System, Charlottesville, VA. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.14 Open the PDF Link PDF for Case 14: What Type of Diabetes? in another window
• Case 15: Type 1 Diabetes versus LADA in a Patient Misdiagnosed with Type 2 Diabetes By Cecilia C. Low Wang, MD Cecilia C. Low Wang, MD 1 Department of Medicine Division of Endocrinology, Metabolism and Diabetes; University of Colorado Anschutz Medical Campus School of Medicine, Aurora, CO. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.15 Open the PDF Link PDF for Case 15: Type 1 Diabetes versus LADA in a Patient Misdiagnosed with Type 2 Diabetes in another window
• Case 16: Type 1 Diabetes Can Present at Any Age By David S.H. Bell, MB David S.H. Bell, MB 1 Clinical Professor, University of Alabama. Birmingham, AL. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.16 Open the PDF Link PDF for Case 16: Type 1 Diabetes Can Present at Any Age in another window
• Case 17: Is This Type 2 Diabetes, Type 1 Diabetes, or Late Autoimmune Diabetes in Adults? By Devjit Tripathy, MD, PhD ; Devjit Tripathy, MD, PhD 1 Audie L. Murphy VA Hospital, South Texas Veterans Health Care System, San Antonio, TX. Search for other works by this author on: This Site PubMed Google Scholar Sheila Pinkson, MPAS, PA-C ; Sheila Pinkson, MPAS, PA-C 1 Audie L. Murphy VA Hospital, South Texas Veterans Health Care System, San Antonio, TX. Search for other works by this author on: This Site PubMed Google Scholar Maureen Koops, MD ; Maureen Koops, MD 1 Audie L. Murphy VA Hospital, South Texas Veterans Health Care System, San Antonio, TX. Search for other works by this author on: This Site PubMed Google Scholar Ralph A. DeFronzo, MD Ralph A. DeFronzo, MD 1 Audie L. Murphy VA Hospital, South Texas Veterans Health Care System, San Antonio, TX. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.17 Open the PDF Link PDF for Case 17: Is This Type 2 Diabetes, Type 1 Diabetes, or Late Autoimmune Diabetes in Adults? in another window
• Case 18: A Common Misdiagnosis By Irene E. Schauer, MD, PhD Irene E. Schauer, MD, PhD 1 Department of Medicine, University of Colorado Anschutz Medical Campus School of Medicine, Aurora, CO. 2 Research/Endocrine Sections, Denver Veterans Affairs Medical Center, Denver, CO. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.18 Open the PDF Link PDF for Case 18: A Common Misdiagnosis in another window
• Case 19: Almost All Nonobese Young People with an Acute Onset of Diabetes Have Type 1 Diabetes By David S.H. Bell, MB David S.H. Bell, MB 1 Clinical Professor, University of Alabama, Birmingham, AL. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.19 Open the PDF Link PDF for Case 19: Almost All Nonobese Young People with an Acute Onset of Diabetes Have Type 1 Diabetes in another window
• Case 20: Symptomatic Postprandial Hyperglycemia By Amita Maturu, MD ; Amita Maturu, MD 1 Division of Endocrinology, Diabetes and Metabolism, University of Colorado, Aurora, CO. Search for other works by this author on: This Site PubMed Google Scholar Michael McDermott, MD Michael McDermott, MD 1 Division of Endocrinology, Diabetes and Metabolism, University of Colorado, Aurora, CO. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.20 Open the PDF Link PDF for Case 20: Symptomatic Postprandial Hyperglycemia in another window
• Case 21: A Patient with Newly Diagnosed, Asymptomatic Hyperglycemia By Aidan McElduff, MD Aidan McElduff, MD 1 Discipline of Medicine, Sydney University, Sydney, NSW, Australia. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.21 Open the PDF Link PDF for Case 21: A Patient with Newly Diagnosed, Asymptomatic Hyperglycemia in another window
• Case 22: Glucokinase Maturity-Onset Diabetes of the Young and Pregnancy By Jill Apel, MD ; Jill Apel, MD 1 Division of Endocrinology, Rush University Medical Center, Chicago, IL. Search for other works by this author on: This Site PubMed Google Scholar Chung-Kay Koh, MD Chung-Kay Koh, MD 1 Division of Endocrinology, Rush University Medical Center, Chicago, IL. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.22 Open the PDF Link PDF for Case 22: Glucokinase Maturity-Onset Diabetes of the Young and Pregnancy in another window
• Case 23: Latent Autoimmune Diabetes of the Adult (LADA) in an Elderly Patient By Monica Shah, MD ; Monica Shah, MD 1 Division of Endocrinology, Rush University, Chicago, IL. Search for other works by this author on: This Site PubMed Google Scholar Mahtab Sohrevardi, MD ; Mahtab Sohrevardi, MD 1 Division of Endocrinology, Rush University, Chicago, IL. Search for other works by this author on: This Site PubMed Google Scholar David Baldwin, MD David Baldwin, MD 1 Division of Endocrinology, Rush University, Chicago, IL. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.23 Open the PDF Link PDF for Case 23: Latent Autoimmune Diabetes of the Adult (LADA) in an Elderly Patient in another window
• Case 24: A Diagnostic Dilemma in a Patient with Elevated Glycosylated Hemoglobin By Shalini Paturi, MD ; Shalini Paturi, MD 1 Endocrinology Division, Department of Medicine, Rosalind Franklin University of Medicine and Science/Chicago Medical School, North Chicago, IL. 2 Endocrinology Section, Department of Medicine, Captain James A. Lovell Federal Health Care Center, North Chicago, IL. Search for other works by this author on: This Site PubMed Google Scholar Janice L. Gilden, MS, MD, FCP, FACE Janice L. Gilden, MS, MD, FCP, FACE 1 Endocrinology Division, Department of Medicine, Rosalind Franklin University of Medicine and Science/Chicago Medical School, North Chicago, IL. 2 Endocrinology Section, Department of Medicine, Captain James A. Lovell Federal Health Care Center, North Chicago, IL. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.24 Open the PDF Link PDF for Case 24: A Diagnostic Dilemma in a Patient with Elevated Glycosylated Hemoglobin in another window
• Case 25: An Unexplained Decline in HbA1c in Spite of Persistent Hyperglycemia By David S.H. Bell, MB David S.H. Bell, MB 1 Clinical Professor, University of Alabama, Birmingham, AL. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.25 Open the PDF Link PDF for Case 25: An Unexplained Decline in HbA1c in Spite of Persistent Hyperglycemia in another window
• Case 26: What to Do with Discrepant HbA1c and SMBG Results? The Utility of Fructosamine and Glycated Albumin By Tatiana Gandrabura, MD ; Tatiana Gandrabura, MD 1 Temple University School of Medicine, Philadelphia, PA. Search for other works by this author on: This Site PubMed Google Scholar Daniel J. Rubin, MD, MSc Daniel J. Rubin, MD, MSc 1 Temple University School of Medicine, Philadelphia, PA. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.26 Open the PDF Link PDF for Case 26: What to Do with Discrepant HbA1c and SMBG Results? The Utility of Fructosamine and Glycated Albumin in another window
• Case 27: A “Tricky” Low HbA 1c By Chiara Mazzucchelli, MD ; Chiara Mazzucchelli, MD 1 Department of Internal Medicine, University of Genova, Genova, Italy. Search for other works by this author on: This Site PubMed Google Scholar Caterina Bordone, MD ; Caterina Bordone, MD 1 Department of Internal Medicine, University of Genova, Genova, Italy. Search for other works by this author on: This Site PubMed Google Scholar Davide Maggi, MD, PhD ; Davide Maggi, MD, PhD 1 Department of Internal Medicine, University of Genova, Genova, Italy. Search for other works by this author on: This Site PubMed Google Scholar Renzo Cordera, MD Renzo Cordera, MD 1 Department of Internal Medicine, University of Genova, Genova, Italy. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.27 Open the PDF Link PDF for Case 27: A “Tricky” Low HbA_1c in another window
• Case 28: Use of Insulin U-500 in a Patient with Severe Insulin Resistance By Hussain Mahmud, MBBS ; Hussain Mahmud, MBBS 1 Clinical Assistant Professor of Medicine, Division of Endocrinology, University of Pittsburgh Medical Center, Pittsburgh, PA. Search for other works by this author on: This Site PubMed Google Scholar Mary T. Korytkowski, MD Mary T. Korytkowski, MD 2 Professor of Medicine, Division of Endocrinology, University of Pittsburgh Medical Center, Pittsburgh, PA. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.28 Open the PDF Link PDF for Case 28: Use of Insulin U-500 in a Patient with Severe Insulin Resistance in another window
• Case 29: Effective Use of U-500 Insulin via Insulin Pump in a Type 2 Diabetes Patient with Severe Insulin Resistance By Vijay babu Balakrishnan, MD ; Vijay babu Balakrishnan, MD 1 Section of Endocrinology, Diabetes and Metabolism, Temple University School of Medicine, Philadelphia, PA. Search for other works by this author on: This Site PubMed Google Scholar Elias S. Siraj, MD Elias S. Siraj, MD 1 Section of Endocrinology, Diabetes and Metabolism, Temple University School of Medicine, Philadelphia, PA. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.29 Open the PDF Link PDF for Case 29: Effective Use of U-500 Insulin via Insulin Pump in a Type 2 Diabetes Patient with Severe Insulin Resistance in another window
• Case 30: U-500 Insulin Pump Case By Anthony L. McCall, MD, PhD, FACP Anthony L. McCall, MD, PhD, FACP 1 James M. Moss Professor of Medicine, University of Virginia, School of Medicine and Health System, Charlottesville, VA. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.30 Open the PDF Link PDF for Case 30: U-500 Insulin Pump Case in another window
• Case 31: Difficulties in Managing Patients with Insulin Resistance: Alternatives to U-500 Insulin By Narmada Movva, MD ; Narmada Movva, MD 1 Endocrinology Division, Department of Medicine, Rosalind Franklin University of Medicine and Science/Chicago Medical School, North Chicago, IL. 2 Endocrinology Section, Department of Medicine, Captain James A. Lovell Federal Health Care Center, North Chicago, IL. Search for other works by this author on: This Site PubMed Google Scholar Boby G. Theckedath, MD, FACE ; Boby G. Theckedath, MD, FACE 1 Endocrinology Division, Department of Medicine, Rosalind Franklin University of Medicine and Science/Chicago Medical School, North Chicago, IL. 2 Endocrinology Section, Department of Medicine, Captain James A. Lovell Federal Health Care Center, North Chicago, IL. Search for other works by this author on: This Site PubMed Google Scholar Janice L. Gilden, MS, MD, FCP, FACE Janice L. Gilden, MS, MD, FCP, FACE 1 Endocrinology Division, Department of Medicine, Rosalind Franklin University of Medicine and Science/Chicago Medical School, North Chicago, IL. 2 Endocrinology Section, Department of Medicine, Captain James A. Lovell Federal Health Care Center, North Chicago, IL. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.31 Open the PDF Link PDF for Case 31: Difficulties in Managing Patients with Insulin Resistance: Alternatives to U-500 Insulin in another window
• Case 32: Management Issues in the Syndrome of Autoantibodies to the Insulin Receptor (Type B Insulin Resistance) By Elaine Cochran, MSN, CRNP ; Elaine Cochran, MSN, CRNP 1 National Institutes of Health, National Institute of Diabetes, Digestive, and Kidney Diseases, Diabetes, Endocrine, and Obesity Branch, Bethesda, MD. Search for other works by this author on: This Site PubMed Google Scholar Rebecca Brown, MD, MhSc ; Rebecca Brown, MD, MhSc 1 National Institutes of Health, National Institute of Diabetes, Digestive, and Kidney Diseases, Diabetes, Endocrine, and Obesity Branch, Bethesda, MD. Search for other works by this author on: This Site PubMed Google Scholar Phillip Gorden, MD Phillip Gorden, MD 1 National Institutes of Health, National Institute of Diabetes, Digestive, and Kidney Diseases, Diabetes, Endocrine, and Obesity Branch, Bethesda, MD. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.32 Open the PDF Link PDF for Case 32: Management Issues in the Syndrome of Autoantibodies to the Insulin Receptor (Type B Insulin Resistance) in another window
• Case 33: Type B Insulin Resistance By Nisha Bincent Jacob, APN, FNP-C, CDE, MBA ; Nisha Bincent Jacob, APN, FNP-C, CDE, MBA 1 University of Texas Southwestern Medical Center, Department of Internal Medicine, Division of Endocrinology and Metabolism, Dallas, TX. Search for other works by this author on: This Site PubMed Google Scholar Hilary Trevino, APN, FNP-C ; Hilary Trevino, APN, FNP-C 1 University of Texas Southwestern Medical Center, Department of Internal Medicine, Division of Endocrinology and Metabolism, Dallas, TX. Search for other works by this author on: This Site PubMed Google Scholar Chanhaeng Rhee, MD, MBA Chanhaeng Rhee, MD, MBA 1 University of Texas Southwestern Medical Center, Department of Internal Medicine, Division of Endocrinology and Metabolism, Dallas, TX. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.33 Open the PDF Link PDF for Case 33: Type B Insulin Resistance in another window
• Case 34: Adhering or Not? That Is the Question: A Case of Glucolipotoxicity and Concentrated Insulin By Sanaa Deshmukh, MD ; Sanaa Deshmukh, MD 1 Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Missouri, Columbia, MO. Search for other works by this author on: This Site PubMed Google Scholar Rino Buzzola, MD ; Rino Buzzola, MD 1 Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Missouri, Columbia, MO. Search for other works by this author on: This Site PubMed Google Scholar Mariana Touza, MD ; Mariana Touza, MD 1 Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Missouri, Columbia, MO. Search for other works by this author on: This Site PubMed Google Scholar Michael Gardner, MD ; Michael Gardner, MD 1 Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Missouri, Columbia, MO. Search for other works by this author on: This Site PubMed Google Scholar James R. Sowers, MD James R. Sowers, MD 1 Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Missouri, Columbia, MO. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.34 Open the PDF Link PDF for Case 34: Adhering or Not? That Is the Question: A Case of Glucolipotoxicity and Concentrated Insulin in another window
• Case 35: Cosecreting Adrenal Tumor Causing Severe Insulin Resistance By Kathya Rivera, MD ; Kathya Rivera, MD 1 Division of Endocrinology, Diabetes and Metabolism, University of Florida, Gainesville, FL. Search for other works by this author on: This Site PubMed Google Scholar Kenneth Cusi, MD ; Kenneth Cusi, MD 1 Division of Endocrinology, Diabetes and Metabolism, University of Florida, Gainesville, FL. 2 Division of Endocrinology, Diabetes and Metabolism, Malcom Randall VAMC, Gainesville, FL. Search for other works by this author on: This Site PubMed Google Scholar Catherine Edwards, MD Catherine Edwards, MD 1 Division of Endocrinology, Diabetes and Metabolism, University of Florida, Gainesville, FL. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.35 Open the PDF Link PDF for Case 35: Cosecreting Adrenal Tumor Causing Severe Insulin Resistance in another window
• Case 36: Management of Severe Insulin Resistance in a Pregnant Patient with Type 2 Diabetes: The Use of U-500 Regular Insulin via Continuous Subcutaneous Infusion By Tiffany Hor, MD ; Tiffany Hor, MD 1 Division of Endocrinology, Rush University, Chicago, IL. Search for other works by this author on: This Site PubMed Google Scholar David Baldwin, MD David Baldwin, MD 1 Division of Endocrinology, Rush University, Chicago, IL. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.36 Open the PDF Link PDF for Case 36: Management of Severe Insulin Resistance in a Pregnant Patient with Type 2 Diabetes: The Use of U-500 Regular Insulin via Continuous Subcutaneous Infusion in another window
• Case 37: Diabetes in Hereditary Hemochromatosis By Donald A. McClain, MD, PhD Donald A. McClain, MD, PhD 1 Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, UT. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.37 Open the PDF Link PDF for Case 37: Diabetes in Hereditary Hemochromatosis in another window
• Case 38: Challenging Insights from Albuminuria Early in the Course of Disease By Cem Demirci, MD ; Cem Demirci, MD 1 Department of Endocrinology, Connecticut Children’s Medical Center, Hartford, CT. Search for other works by this author on: This Site PubMed Google Scholar Vered Lewy-Weiss, MD ; Vered Lewy-Weiss, MD 2 Children’s Hospital of Pittsburgh of UPMC, Pittsburgh, PA. Search for other works by this author on: This Site PubMed Google Scholar Mark A. Sperling, MBBS, FRACP Mark A. Sperling, MBBS, FRACP 2 Children’s Hospital of Pittsburgh of UPMC, Pittsburgh, PA. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.38 Open the PDF Link PDF for Case 38: Challenging Insights from Albuminuria Early in the Course of Disease in another window
• Case 39: Copresentation of Addison’s Disease and Type 1 Diabetes in a 9-Year-Old Boy By Shideh Majidi, MD ; Shideh Majidi, MD 1 Pediatric Endocrinology Fellow, University of Colorado Denver, Aurora, CO. Search for other works by this author on: This Site PubMed Google Scholar Jennifer Raymond, MD, MCR Jennifer Raymond, MD, MCR 2 Assistant Professor, Pediatric Endocrinology, Barbara Davis Center for Diabetes, University of Colorado Denver, Aurora, CO. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.39 Open the PDF Link PDF for Case 39: Copresentation of Addison’s Disease and Type 1 Diabetes in a 9-Year-Old Boy in another window
• Case 40: Diagnosis of Addison’s Disease and Type 1 Diabetes in Twin Boys By Andrea Dann Urban, MSN, PNP-BC, CDE ; Andrea Dann Urban, MSN, PNP-BC, CDE 1 Yale Children’s Diabetes Program, Associate Clinical Faculty, Yale University School of Nursing, New Haven, CT. Search for other works by this author on: This Site PubMed Google Scholar William V. Tamborlane, MD William V. Tamborlane, MD 2 Professor of Pediatrics, Department of Pediatrics, Chief, Pediatric Endocrinology, Deputy Director, Yale Center for Clinical Investigation, Director, Children’s Diabetes Program, Yale School of Medicine, New Haven, CT. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.40 Open the PDF Link PDF for Case 40: Diagnosis of Addison’s Disease and Type 1 Diabetes in Twin Boys in another window
• Case 41: New-Onset Type 1 Diabetes, Addison’s Disease, and Hypothyroidism: A Case of Autoimmune Polyendocrine Syndrome Type 2 By Lauren Golden, MD ; Lauren Golden, MD 1 Assistant Professor Clinical Medicine, Naomi Berrie Diabetes Center, Columbia University Medical Center, New York, NY. Search for other works by this author on: This Site PubMed Google Scholar Robin Goland, MD Robin Goland, MD 2 J. Merrill Eastman Professor of Clinical Diabetes, Columbia University Medical Center, New York, NY. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.41 Open the PDF Link PDF for Case 41: New-Onset Type 1 Diabetes, Addison’s Disease, and Hypothyroidism: A Case of Autoimmune Polyendocrine Syndrome Type 2 in another window
• Case 42: The Slow Progression of Type 1 Diabetes as Part of Autoimmune Polyendocrine Syndrome Type 2 By Natalia Pertzeva, MD ; Natalia Pertzeva, MD 1 Dnepropetrovsk Medical Academy, Dnepropetrovsk, Ukraine. Search for other works by this author on: This Site PubMed Google Scholar Boris Mankovsky, MD, PhD Boris Mankovsky, MD, PhD 2 National Medical Academy for Postgraduate Education, Kiev, Ukraine. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.42 Open the PDF Link PDF for Case 42: The Slow Progression of Type 1 Diabetes as Part of Autoimmune Polyendocrine Syndrome Type 2 in another window
• Case 43: Atypical Type 2 Diabetes with Profound Dyslipidemia By Jeremy H. Pettus, MD ; Jeremy H. Pettus, MD 1 Endocrinology Fellow, Division of Endocrinology and Metabolism, University of California, San Diego, CA. Search for other works by this author on: This Site PubMed Google Scholar Robert R. Henry, MD Robert R. Henry, MD 2 Professor of Medicine, Division of Endocrinology and Metabolism, University of California, San Diego, CA; Chief, Section of Diabetes, Endocrinology and Metabolism; Director, Center for Metabolic Research, VA San Diego Healthcare System, San Diego, CA. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.43 Open the PDF Link PDF for Case 43: Atypical Type 2 Diabetes with Profound Dyslipidemia in another window
• Case 44: Patient with Diabetes Who Has Hemiballismus By Miriam Padilla, MD, CDE ; Miriam Padilla, MD, CDE 1 Fellow, Department of Endocrinology and Diabetes at University of Southern California. Search for other works by this author on: This Site PubMed Google Scholar Jorge Mestman, MD Jorge Mestman, MD 2 Professor of Clinical Medicine in the Department of Endocrinology and Diabetes at University of Southern California, Professor of Clinical Medicine in the Department of Obstetrics and Gynecology at University of Southern California. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.44 Open the PDF Link PDF for Case 44: Patient with Diabetes Who Has Hemiballismus in another window
• Case 45: A Case of Diabetic Myonecrosis By Umal Azmat, MD ; Umal Azmat, MD 1 Division of Endocrinology, Diabetes and Metabolism, Ohio State University Wexner Medical Center, Columbus, OH. Search for other works by this author on: This Site PubMed Google Scholar Jason E. Payne, MD ; Jason E. Payne, MD 2 Division of Radiology, Ohio State University Wexner Medical Center, Columbus, OH. Search for other works by this author on: This Site PubMed Google Scholar Kathleen Dungan, MD ; Kathleen Dungan, MD 1 Division of Endocrinology, Diabetes and Metabolism, Ohio State University Wexner Medical Center, Columbus, OH. Search for other works by this author on: This Site PubMed Google Scholar Steven W. Ing, MD Steven W. Ing, MD 1 Division of Endocrinology, Diabetes and Metabolism, Ohio State University Wexner Medical Center, Columbus, OH. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.45 Open the PDF Link PDF for Case 45: A Case of Diabetic Myonecrosis in another window
• Case 46: A Case of Stiff Person Syndrome in a Patient with Type 1 Diabetes By Matthew P. Gilbert, DO, MPH ; Matthew P. Gilbert, DO, MPH 1 Department of Medicine, Division of Endocrinology and Diabetes, University of Vermont College of Medicine, Burlington, VT. Search for other works by this author on: This Site PubMed Google Scholar Muriel H. Nathan, MD, PhD Muriel H. Nathan, MD, PhD 1 Department of Medicine, Division of Endocrinology and Diabetes, University of Vermont College of Medicine, Burlington, VT. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.46 Open the PDF Link PDF for Case 46: A Case of Stiff Person Syndrome in a Patient with Type 1 Diabetes in another window
• Case 47: Stiff Person Syndrome in a Patient with Multiple Autoimmune Diseases By Jing Hughes, MD, PhD ; Jing Hughes, MD, PhD 1 Professor of Medicine, Director, Fellowship in Endocrinology, Diabetes and Metabolism, Division of Endocrinology, Metabolism and Lipid Research, Washington University School of Medicine, St. Louis, MO. Search for other works by this author on: This Site PubMed Google Scholar Janet B. McGill, MD Janet B. McGill, MD 1 Professor of Medicine, Director, Fellowship in Endocrinology, Diabetes and Metabolism, Division of Endocrinology, Metabolism and Lipid Research, Washington University School of Medicine, St. Louis, MO. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.47 Open the PDF Link PDF for Case 47: Stiff Person Syndrome in a Patient with Multiple Autoimmune Diseases in another window
• Case 48: Glycogenic Hepatopathy in an Adolescent with Type 1 Diabetes By Nehama Zuckerman-Levin, MD ; Nehama Zuckerman-Levin, MD 1 Department of Pediatrics, Pediatric Diabetes and Obesity Clinic, Rambam Health Care Campus, Bruce Rappaport Faculty of Medicine, Technion, Haifa, Israel. Search for other works by this author on: This Site PubMed Google Scholar Oz Mordechai, MD ; Oz Mordechai, MD 1 Department of Pediatrics, Pediatric Diabetes and Obesity Clinic, Rambam Health Care Campus, Bruce Rappaport Faculty of Medicine, Technion, Haifa, Israel. Search for other works by this author on: This Site PubMed Google Scholar Naim Shehadeh, MD Naim Shehadeh, MD 1 Department of Pediatrics, Pediatric Diabetes and Obesity Clinic, Rambam Health Care Campus, Bruce Rappaport Faculty of Medicine, Technion, Haifa, Israel. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.48 Open the PDF Link PDF for Case 48: Glycogenic Hepatopathy in an Adolescent with Type 1 Diabetes in another window
• Case 49: Glycemic Control in a Child with Type 1 Diabetes and Autoimmune Hepatitis By Sandro Muntoni, MD, PhD ; Sandro Muntoni, MD, PhD 1 Department of Biomedical Sciences, University School of Cagliari and Centre for Metabolic Diseases and Atherosclerosis, The ME.DI.CO Association, Cagliari, Italy. Search for other works by this author on: This Site PubMed Google Scholar Mauro Congia, MD Mauro Congia, MD 2 Pediatric Gastroenterologic Unity, Microcitemic Hospital, ASL 8, Cagliari, Italy. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.49 Open the PDF Link PDF for Case 49: Glycemic Control in a Child with Type 1 Diabetes and Autoimmune Hepatitis in another window
• Case 50: Dizziness, Lightheadedness, and Syncope in a Patient with Type 2 Diabetes By Shalini Paturi, MD ; Shalini Paturi, MD 1 Endocrinology Division, Department of Medicine, Rosalind Franklin University of Medicine and Science/Chicago Medical School, North Chicago, IL. 2 Endocrinology Section, Department of Medicine, Captain James A. Lovell Federal Health Care Center, North Chicago, IL. Search for other works by this author on: This Site PubMed Google Scholar Janice L. Gilden, MS, MD, FCP, FACE Janice L. Gilden, MS, MD, FCP, FACE 1 Endocrinology Division, Department of Medicine, Rosalind Franklin University of Medicine and Science/Chicago Medical School, North Chicago, IL. 2 Endocrinology Section, Department of Medicine, Captain James A. Lovell Federal Health Care Center, North Chicago, IL. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.50 Open the PDF Link PDF for Case 50: Dizziness, Lightheadedness, and Syncope in a Patient with Type 2 Diabetes in another window
• Case 51: Growth Hormone Excess-Induced Diabetic Ketoacidosis By Andrew P. Demidowich, MD ; Andrew P. Demidowich, MD 1 Section on Pediatric Diabetes and Metabolism, Diabetes, Endocrinology, and Obesity Branch, NIDDK, National Institutes of Health, Bethesda, MD. Search for other works by this author on: This Site PubMed Google Scholar Maya Lodish, MD ; Maya Lodish, MD 2 Heritable Disorders Branch, NICHD, National Institutes of Health, Bethesda, MD. Search for other works by this author on: This Site PubMed Google Scholar Kristina I. Rother, MD, MHSc Kristina I. Rother, MD, MHSc 1 Section on Pediatric Diabetes and Metabolism, Diabetes, Endocrinology, and Obesity Branch, NIDDK, National Institutes of Health, Bethesda, MD. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.51 Open the PDF Link PDF for Case 51: Growth Hormone Excess-Induced Diabetic Ketoacidosis in another window
• Case 52: Refractory Angina in a Patient with Type 2 Diabetes By Mikhail Kosiborod, MD Mikhail Kosiborod, MD 1 Professor of Medicine, Saint Luke’s Mid America Heart Institute, University of Missouri-Kansas City, Kansas City, MO. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.52 Open the PDF Link PDF for Case 52: Refractory Angina in a Patient with Type 2 Diabetes in another window
• Case 53: Glycemic Control in a Patient with Type 2 Diabetes Undergoing Cardiac Surgery By M. Kathleen Figaro, MD, MS M. Kathleen Figaro, MD, MS 1 Medical Director, Diabetes Care Center, Endocrinology, Genesis Health Care, Bettendorf, IA. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.53 Open the PDF Link PDF for Case 53: Glycemic Control in a Patient with Type 2 Diabetes Undergoing Cardiac Surgery in another window
• Case 54: Inpatient Insulin Management for Complex Enteral Feedings By Anna Beth Barton, MD ; Anna Beth Barton, MD 1 Endocrinology Fellow, Department of Medicine Division of Endocrinology, Metabolism, and Nutrition, Duke University Medical Center, Durham, NC. Search for other works by this author on: This Site PubMed Google Scholar Kathryn J. Evans, DNP, FNP-BC ; Kathryn J. Evans, DNP, FNP-BC 2 Division of Endocrinology, Metabolism and Nutrition, Duke University Medical Center, Durham, NC. Search for other works by this author on: This Site PubMed Google Scholar Lillian F. Lien, MD Lillian F. Lien, MD 3 Medical Director, Duke Inpatient Diabetes Management Associate Professor, Department of Medicine Division of Endocrinology, Metabolism, and Nutrition, Duke University Medical Center, Durham, NC. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.54 Open the PDF Link PDF for Case 54: Inpatient Insulin Management for Complex Enteral Feedings in another window
• Case 55: Glycemic Control in a Patient with Type 1 Diabetes and Severe Burns By R. Matthew Hawkins, PA-C ; R. Matthew Hawkins, PA-C 1 Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Colorado Anschutz Medical Center, Aurora CO. Search for other works by this author on: This Site PubMed Google Scholar Boris Draznin, MD, PhD Boris Draznin, MD, PhD 1 Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Colorado Anschutz Medical Center, Aurora CO. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.55 Open the PDF Link PDF for Case 55: Glycemic Control in a Patient with Type 1 Diabetes and Severe Burns in another window
• Case 56: Combined Effect of Intravenous Insulin Infusion and Subcutaneous Rapid-Acting Insulin for Glycemic Control in Severe Insulin Resistance By Magdalena Szkudlinska, MD ; Magdalena Szkudlinska, MD 1 University of Washington School of Medicine, Division of Metabolism, Endocrinology, & Nutrition, Seattle, WA. Search for other works by this author on: This Site PubMed Google Scholar Irl B. Hirsch, MD Irl B. Hirsch, MD 1 University of Washington School of Medicine, Division of Metabolism, Endocrinology, & Nutrition, Seattle, WA. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.56 Open the PDF Link PDF for Case 56: Combined Effect of Intravenous Insulin Infusion and Subcutaneous Rapid-Acting Insulin for Glycemic Control in Severe Insulin Resistance in another window
• Case 57: Therapeutic Hypothermia and Severe Insulin Resistance in Patients with Diabetes and Cardiac Arrest By Stacey Seggelke, RD, MS, CDE ; Stacey Seggelke, RD, MS, CDE 1 Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO. Search for other works by this author on: This Site PubMed Google Scholar Boris Draznin, MD, PhD Boris Draznin, MD, PhD 1 Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.57 Open the PDF Link PDF for Case 57: Therapeutic Hypothermia and Severe Insulin Resistance in Patients with Diabetes and Cardiac Arrest in another window
• Case 58: Extreme Insulin Resistance Following Heart Transplant By Suruchi Gupta, MBBS, MPH ; Suruchi Gupta, MBBS, MPH 1 Division of Endocrinology, Metabolism and Molecular Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL. Search for other works by this author on: This Site PubMed Google Scholar Diana Johnson Oakes, APRN-BC ; Diana Johnson Oakes, APRN-BC 1 Division of Endocrinology, Metabolism and Molecular Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL. Search for other works by this author on: This Site PubMed Google Scholar Ashley Therasse, MD ; Ashley Therasse, MD 1 Division of Endocrinology, Metabolism and Molecular Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL. Search for other works by this author on: This Site PubMed Google Scholar Amisha Wallia, MD, MS ; Amisha Wallia, MD, MS 1 Division of Endocrinology, Metabolism and Molecular Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL. Search for other works by this author on: This Site PubMed Google Scholar Mark E. Molitch, MD Mark E. Molitch, MD 1 Division of Endocrinology, Metabolism and Molecular Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.58 Open the PDF Link PDF for Case 58: Extreme Insulin Resistance Following Heart Transplant in another window
• Case 59: Glycemic Control after Left Ventricular Assist Device Placement in a Patient with Type 2 Diabetes By Gitana Staskus, MD Gitana Staskus, MD 1 Assistant Professor of Medicine, Division of Endocrinology, Metabolism and Diabetes, University of Utah, School of Medicine. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.59 Open the PDF Link PDF for Case 59: Glycemic Control after Left Ventricular Assist Device Placement in a Patient with Type 2 Diabetes in another window
• Case 60: Management of Diabetic Ketoacidosis in a Patient on Hemodialysis By Roopashree Prabhushankar, MD ; Roopashree Prabhushankar, MD 1 Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Missouri, Harry S. Truman Memorial Veterans’ Hospital, Columbia, MO. Search for other works by this author on: This Site PubMed Google Scholar Sofia Syed, MD ; Sofia Syed, MD 1 Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Missouri, Harry S. Truman Memorial Veterans’ Hospital, Columbia, MO. Search for other works by this author on: This Site PubMed Google Scholar James R. Sowers, MD, FACE, FACP, FAHA James R. Sowers, MD, FACE, FACP, FAHA 1 Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Missouri, Harry S. Truman Memorial Veterans’ Hospital, Columbia, MO. 2 Department of Medical Pharmacology and Physiology, University of Missouri, Harry S. Truman Memorial Veterans’ Hospital, Columbia, MO. 3 Diabetes and Cardiovascular Center, University of Missouri, Harry S. Truman Memorial Veterans’ Hospital, Columbia, MO. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.60 Open the PDF Link PDF for Case 60: Management of Diabetic Ketoacidosis in a Patient on Hemodialysis in another window
• Case 61: New Diabetes Emergency: Acute Rhabdomyolysis Complicating Hyperglycemic Hyperosmolar Coma By Cherie Vaz, MD ; Cherie Vaz, MD 1 Section of Endocrinology, Department of Medicine, Temple University School of Medicine, Philadelphia, PA. Search for other works by this author on: This Site PubMed Google Scholar Ajay Chaudhuri, MD, MRCP Ajay Chaudhuri, MD, MRCP 2 Department of Endocrinology, State University of New York, University at Buffalo and Kaleida Health, Buffalo, NY. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.61 Open the PDF Link PDF for Case 61: New Diabetes Emergency: Acute Rhabdomyolysis Complicating Hyperglycemic Hyperosmolar Coma in another window
• Case 62: Transitioning from Intravenous to Subcutaneous Insulin in a Complicated Patient By Kathryn J. Evans, DNP, FNP-BC ; Kathryn J. Evans, DNP, FNP-BC 1 Division of Endocrinology, Metabolism and Nutrition, Duke University Medical Center, Durham, NC. Search for other works by this author on: This Site PubMed Google Scholar Lillian F. Lien, MD Lillian F. Lien, MD 2 Duke Inpatient Diabetes Management, Department of Medicine, Division of Endocrinology, Metabolism, and Nutrition, Duke University Medical Center, Durham, NC. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.62 Open the PDF Link PDF for Case 62: Transitioning from Intravenous to Subcutaneous Insulin in a Complicated Patient in another window
• Case 63: Failure to Coordinate Diabetes Care between Hospital and Ambulatory Settings: A Threat to Safe and Quality Patient Care By Shawn Peavie, DO ; Shawn Peavie, DO 1 University of Cincinnati College of Medicine; Division of Endocrinology, Diabetes, and Metabolism, Cincinnati, OH. Search for other works by this author on: This Site PubMed Google Scholar Mercedes Falciglia, MD Mercedes Falciglia, MD 1 University of Cincinnati College of Medicine; Division of Endocrinology, Diabetes, and Metabolism, Cincinnati, OH. 2 Cincinnati Veterans Affairs Medical Center, Cincinnati, OH. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.63 Open the PDF Link PDF for Case 63: Failure to Coordinate Diabetes Care between Hospital and Ambulatory Settings: A Threat to Safe and Quality Patient Care in another window
• Case 64: Preventing Readmission: Translating the Hospital Diabetes Regimen into a Home Regimen that Is Safe, Effective, and Easy to Follow By Jane Jeffrie Seley, DNP, MPH, MSN, BC-ADM, CDE, CDTC Jane Jeffrie Seley, DNP, MPH, MSN, BC-ADM, CDE, CDTC 1 New York Presbyterian/Weill Cornell Medical Center, New York, NY. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.64 Open the PDF Link PDF for Case 64: Preventing Readmission: Translating the Hospital Diabetes Regimen into a Home Regimen that Is Safe, Effective, and Easy to Follow in another window
• Case 65: Novel Combination Therapy for Type 2 Diabetes By Donna White, RPh, CDE, BCACP ; Donna White, RPh, CDE, BCACP 1 University of Virginia Health System, Department of Pharmacy, Charlottesville, VA. Search for other works by this author on: This Site PubMed Google Scholar Svetlana Goldman, PharmD Svetlana Goldman, PharmD 1 University of Virginia Health System, Department of Pharmacy, Charlottesville, VA. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.65 Open the PDF Link PDF for Case 65: Novel Combination Therapy for Type 2 Diabetes in another window
• Case 66: Do Many People with Type 2 Diabetes Really Need Insulin? By Stanley S. Schwartz, MD Stanley S. Schwartz, MD 1 Main Line Health System, Wynnewood, PA. 2 University of Pennsylvania, Philadelphia, PA. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.66 Open the PDF Link PDF for Case 66: Do Many People with Type 2 Diabetes <em>Really</em> Need Insulin? in another window
• Case 67: Glycemic Control in a Patient with Type 1 Diabetes and Peritoneal Dialysis By Nadir Khir, MD ; Nadir Khir, MD 1 Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Missouri, Columbia, MO. Search for other works by this author on: This Site PubMed Google Scholar Stephen Brietzke, MD ; Stephen Brietzke, MD 1 Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Missouri, Columbia, MO. Search for other works by this author on: This Site PubMed Google Scholar James R. Sowers, MD James R. Sowers, MD 1 Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Missouri, Columbia, MO. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.67 Open the PDF Link PDF for Case 67: Glycemic Control in a Patient with Type 1 Diabetes and Peritoneal Dialysis in another window
• Case 68: Insulin Allergy in an Insulin-Requiring Patient By Nestoras Mathioudakis, MD Nestoras Mathioudakis, MD 1 Assistant Professor of Medicine, Division of Endocrinology, Diabetes, & Metabolism, Johns Hopkins University School of Medicine, Baltimore, MD. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.68 Open the PDF Link PDF for Case 68: Insulin Allergy in an Insulin-Requiring Patient in another window
• Case 69: Use of 3-Day Continuous Glucose Monitoring to Investigate Persistent Fasting Hyperglycemia in Type 2 Diabetes By Michelle Griffith, MD ; Michelle Griffith, MD 1 Division of Endocrinology and Metabolism, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA. Search for other works by this author on: This Site PubMed Google Scholar Mary Korytkowski, MD Mary Korytkowski, MD 1 Division of Endocrinology and Metabolism, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.69 Open the PDF Link PDF for Case 69: Use of 3-Day Continuous Glucose Monitoring to Investigate Persistent Fasting Hyperglycemia in Type 2 Diabetes in another window
• Case 70: Insulin Injections: What You “See” May Not Be What You Get By Robert J. Rushakoff, MD ; Robert J. Rushakoff, MD 1 Division of Endocrinology and Metabolism, University of California, San Francisco, CA. Search for other works by this author on: This Site PubMed Google Scholar Mary M. Sullivan, DNP, RN, ANP-BC, CDE, FAAN ; Mary M. Sullivan, DNP, RN, ANP-BC, CDE, FAAN 2 Department of Nursing, University of California, San Francisco, CA. Search for other works by this author on: This Site PubMed Google Scholar Arti Shah, MD ; Arti Shah, MD 3 Division of Endocrinology and Metabolism, University of California, San Francisco, CA. Search for other works by this author on: This Site PubMed Google Scholar Heidemarie Windham MacMaster, PharmD, CDE Heidemarie Windham MacMaster, PharmD, CDE 4 Department of Pharmaceutical Services, University of California, San Francisco, CA. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.70 Open the PDF Link PDF for Case 70: Insulin Injections: What You “See” May Not Be What You Get in another window
• Case 71: Prolonged Insulin-Free Management of Type 1 Diabetes By Danielle Castillo, MD ; Danielle Castillo, MD 1 Division of Endocrinology & Metabolism, Eastern Virginia Medical School, Norfolk, VA. Search for other works by this author on: This Site PubMed Google Scholar Joseph Aloi, MD, FACE Joseph Aloi, MD, FACE 1 Division of Endocrinology & Metabolism, Eastern Virginia Medical School, Norfolk, VA. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.71 Open the PDF Link PDF for Case 71: Prolonged Insulin-Free Management of Type 1 Diabetes in another window
• Case 72: Delayed Response to NPH Insulin By Mayer B. Davidson, MD Mayer B. Davidson, MD 1 Department of Internal Medicine, Charles R. Drew University, Los Angeles, CA. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.72 Open the PDF Link PDF for Case 72: Delayed Response to NPH Insulin in another window
• Case 73: Reversal of Type 2 Diabetes by Weight Loss Despite Presence of Macro- and Microvascular Complications By Carl Peters, MB, ChB ; Carl Peters, MB, ChB 1 Newcastle Magnetic Resonance Centre, Campus for Ageing and Vitality, Newcastle upon Tyne, England. Search for other works by this author on: This Site PubMed Google Scholar Sarah Steven, MB, ChB ; Sarah Steven, MB, ChB 1 Newcastle Magnetic Resonance Centre, Campus for Ageing and Vitality, Newcastle upon Tyne, England. Search for other works by this author on: This Site PubMed Google Scholar Roy Taylor, MD Roy Taylor, MD 1 Newcastle Magnetic Resonance Centre, Campus for Ageing and Vitality, Newcastle upon Tyne, England. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.73 Open the PDF Link PDF for Case 73: Reversal of Type 2 Diabetes by Weight Loss Despite Presence of Macro- and Microvascular Complications in another window
• Case 74: Glycemic Control in Older Adults with Diabetes and Use of New SGLT2 Inhibitors By Carolyn Horney, MD ; Carolyn Horney, MD 1 University of Colorado Health Sciences Center, Division of Geriatric Medicine, Aurora, CO. Search for other works by this author on: This Site PubMed Google Scholar Jeffrey Wallace, MD, MPH Jeffrey Wallace, MD, MPH 1 University of Colorado Health Sciences Center, Division of Geriatric Medicine, Aurora, CO. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.74 Open the PDF Link PDF for Case 74: Glycemic Control in Older Adults with Diabetes and Use of New SGLT2 Inhibitors in another window
• Case 75: Blood Glucose Control of Patients with Hypertriglyceridemia By Henning Beck-Nielsen, DMSc Henning Beck-Nielsen, DMSc 1 Department of Endocrinology, Odense University Hospital, Odense, Denmark. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.75 Open the PDF Link PDF for Case 75: Blood Glucose Control of Patients with Hypertriglyceridemia in another window
• Case 76: No Effect of Gluten-Free Diet in Prevention of Autoimmune Type 1 Diabetes and Other Autoimmune Disorders in a Child with Celiac Disease By Sandro Muntoni, MD, PhD ; Sandro Muntoni, MD, PhD 1 Department of Biomedical Sciences, University School of Cagliari and Centre for Metabolic Diseases and Atherosclerosis, The ME.DI.CO. Association, Cagliari, Italy. Search for other works by this author on: This Site PubMed Google Scholar Mauro Congia, MD Mauro Congia, MD 2 Pediatric Gastroenterologic Unity, Microcitemic Hospital, Cagliari, Italy. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.76 Open the PDF Link PDF for Case 76: No Effect of Gluten-Free Diet in Prevention of Autoimmune Type 1 Diabetes and Other Autoimmune Disorders in a Child with Celiac Disease in another window
• Case 77: What Does It Take to Keep Glucose Normal? By Lawrence S. Phillips, MD Lawrence S. Phillips, MD 1 Atlanta VA Medical Center, Decatur, GA. 2 Division of Endocrinology and Metabolism, Department of Medicine, Emory University, School of Medicine, Atlanta, GA. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.77 Open the PDF Link PDF for Case 77: What Does It Take to Keep Glucose Normal? in another window
• Case 78: Psychosocial Stressors and Management in an Adolescent with Type 2 Diabetes By Radha Nandagopal, MD ; Radha Nandagopal, MD 1 Pediatric Endocrinology, Providence Medical Group, Spokane, WA. Search for other works by this author on: This Site PubMed Google Scholar Kristina I. Rother, MD, MHSc Kristina I. Rother, MD, MHSc 2 Section on Pediatric Diabetes and Metabolism, Diabetes, Endocrinology, and Obesity Branch, NIDDK, National Institutes of Health, Bethesda, MD. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.78 Open the PDF Link PDF for Case 78: Psychosocial Stressors and Management in an Adolescent with Type 2 Diabetes in another window
• Case 79: Suicide, Homicide, or Diabetes-Related Incident? By John N. Carter, BSc (Med), MBBS, FRACP, MD John N. Carter, BSc (Med), MBBS, FRACP, MD 1 Clinical Professor of Endocrinology, Sydney Medical School, University of Sydney, Australia. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.79 Open the PDF Link PDF for Case 79: Suicide, Homicide, or Diabetes-Related Incident? in another window
• Case 80: The Case of an Older Woman with Diabetes on Insulin Pump Therapy, Struggling with Cognitive Decline, Hypoglycemia, and Loss of Autonomy By Jennifer M. Hackel, DNP, GNP-BC, CDE ; Jennifer M. Hackel, DNP, GNP-BC, CDE 1 University of Massachusetts Boston, Boston, MA. Search for other works by this author on: This Site PubMed Google Scholar Liselle Douyon, MD ; Liselle Douyon, MD 2 University of Michigan, Endocrinology and Metabolism, Ann Arbor, MI. Search for other works by this author on: This Site PubMed Google Scholar Jeffrey B. Halter, MD Jeffrey B. Halter, MD 3 University of Michigan Geriatrics Center, Ann Arbor, MI. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.80 Open the PDF Link PDF for Case 80: The Case of an Older Woman with Diabetes on Insulin Pump Therapy, Struggling with Cognitive Decline, Hypoglycemia, and Loss of Autonomy in another window
• Case 81: Somnambulism (Sleepwalking) Caused by Nocturnal Hypoglycemia By David S.H. Bell, MB David S.H. Bell, MB 1 Clinical Professor of Medicine, University of Alabama, Birmingham, AL. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.81 Open the PDF Link PDF for Case 81: Somnambulism (Sleepwalking) Caused by Nocturnal Hypoglycemia in another window
• Case 82: Hypoglycemic Unawareness By Amita Maturu, MD ; Amita Maturu, MD 1 Division of Endocrinology, Diabetes and Metabolism, University of Colorado, Aurora, CO. Search for other works by this author on: This Site PubMed Google Scholar Neda Rasouli, MD Neda Rasouli, MD 1 Division of Endocrinology, Diabetes and Metabolism, University of Colorado, Aurora, CO. 2 Denver Veterans Affairs Medical Center, Denver, CO. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.82 Open the PDF Link PDF for Case 82: Hypoglycemic Unawareness in another window
• Case 83: Successful Use of Plasmapheresis in the Treatment of Hypoglycemia Due to Insulin Antibody Syndrome By Pankaj Sharda, MD ; Pankaj Sharda, MD 1 Section of Endocrinology, Diabetes and Metabolism, Temple University School of Medicine, Philadelphia, PA. Search for other works by this author on: This Site PubMed Google Scholar Thottathil Gopan, MD ; Thottathil Gopan, MD 2 Department of Endocrinology, Diabetes and Metabolism, Cleveland Clinic, Cleveland, OH. Search for other works by this author on: This Site PubMed Google Scholar Robert Zimmerman, MD ; Robert Zimmerman, MD 2 Department of Endocrinology, Diabetes and Metabolism, Cleveland Clinic, Cleveland, OH. Search for other works by this author on: This Site PubMed Google Scholar Elias S. Siraj, MD Elias S. Siraj, MD 1 Section of Endocrinology, Diabetes and Metabolism, Temple University School of Medicine, Philadelphia, PA. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.83 Open the PDF Link PDF for Case 83: Successful Use of Plasmapheresis in the Treatment of Hypoglycemia Due to Insulin Antibody Syndrome in another window
• Case 84: Postprandial Hypoglycemia, an Uncommon Presentation of Type 2 Diabetes By Muhammad W. Salam, MD ; Muhammad W. Salam, MD 1 Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Missouri, Columbia, MO. Search for other works by this author on: This Site PubMed Google Scholar James R. Sowers, MD James R. Sowers, MD 1 Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Missouri, Columbia, MO. 2 Department of Medical Pharmacology and Physiology, University of Missouri, Columbia, MO. 3 Diabetes and Cardiovascular Center, University of Missouri, Columbia, MO. 4 University of Missouri, Harry S. Truman Memorial Veterans’ Hospital, Columbia, MO. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.84 Open the PDF Link PDF for Case 84: Postprandial Hypoglycemia, an Uncommon Presentation of Type 2 Diabetes in another window
• Case 85: Factitious Hypoglycemia in a Type 2 Diabetic Patient By Stacey A. Seggelke, MS, RN, CNS, CDE, BC-ADM Stacey A. Seggelke, MS, RN, CNS, CDE, BC-ADM 1 Adult Diabetes Program, University of Colorado Denver, School of Medicine, Denver, CO. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.85 Open the PDF Link PDF for Case 85: Factitious Hypoglycemia in a Type 2 Diabetic Patient in another window
• Case 86: Recurrent Hypoglycemia in a Patient with Type 2 Diabetes By Pavani Srimatkandada, MD ; Pavani Srimatkandada, MD 1 Boston University School of Medicine, Section of Endocrinology, Diabetes, Nutrition and Weight Management, Boston, MA. Search for other works by this author on: This Site PubMed Google Scholar Marie E. McDonnell, MD ; Marie E. McDonnell, MD 1 Boston University School of Medicine, Section of Endocrinology, Diabetes, Nutrition and Weight Management, Boston, MA. Search for other works by this author on: This Site PubMed Google Scholar Sonia Ananthakrishnan, MD Sonia Ananthakrishnan, MD 1 Boston University School of Medicine, Section of Endocrinology, Diabetes, Nutrition and Weight Management, Boston, MA. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.86 Open the PDF Link PDF for Case 86: Recurrent Hypoglycemia in a Patient with Type 2 Diabetes in another window
• Case 87: Munchausen Syndrome: Hypoglycemia in an Obese Woman with Type 2 Diabetes By R. Paul Robertson, MD R. Paul Robertson, MD 1 Professor of Medicine, University of Minnesota, Professor of Medicine and Pharmacology, University of Washington, President Emeritus and Principal Investigator, Pacific Northwest Diabetes Research Institute. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.87 Open the PDF Link PDF for Case 87: Munchausen Syndrome: Hypoglycemia in an Obese Woman with Type 2 Diabetes in another window
• Case 88: The Use of Medical Technologies for the Reduction of Hypoglycemia in Type 1 Diabetes: Technology for Hypoglycemia Reduction By Viral N. Shah, MD ; Viral N. Shah, MD 1 Barbara Davis Center for Diabetes, University of Colorado Denver, Aurora, CO. Search for other works by this author on: This Site PubMed Google Scholar Aaron W. Michels, MD ; Aaron W. Michels, MD 1 Barbara Davis Center for Diabetes, University of Colorado Denver, Aurora, CO. 2 Departments of Internal Medicine and Pediatrics, School of Medicine, University of Colorado, Denver, Aurora, CO. Search for other works by this author on: This Site PubMed Google Scholar Satish K. Garg, MD Satish K. Garg, MD 1 Barbara Davis Center for Diabetes, University of Colorado Denver, Aurora, CO. 2 Departments of Internal Medicine and Pediatrics, School of Medicine, University of Colorado, Denver, Aurora, CO. 3 Editor-in-Chief, Diabetes Technology and Therapeutics , Aurora, CO. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.88 Open the PDF Link PDF for Case 88: The Use of Medical Technologies for the Reduction of Hypoglycemia in Type 1 Diabetes: Technology for Hypoglycemia Reduction in another window
• Case 89: Reversal of Insulin-Requiring Type 2 Diabetes and Development of Hypoglycemia in a Morbidly Obese Patient By David S.H. Bell, MB David S.H. Bell, MB 1 University of Alabama, Birmingham, AL. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.89 Open the PDF Link PDF for Case 89: Reversal of Insulin-Requiring Type 2 Diabetes and Development of Hypoglycemia in a Morbidly Obese Patient in another window
• Case 90: Munchausen-by-Proxy: Hypoglycemia in an Islet Autotransplantation Recipient By R. Paul Robertson, MD R. Paul Robertson, MD 1 Professor of Medicine, University of Minnesota; Professor of Medicine and Pharmacology, University of Washington; President Emeritus and Principal Investigator, Pacific Northwest Diabetes Research Institute. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.90 Open the PDF Link PDF for Case 90: Munchausen-by-Proxy: Hypoglycemia in an Islet Autotransplantation Recipient in another window
• Case 91: Treatment of a Patient with Diabetes and Severe Hypoglycemia By Henning Beck-Nielsen, DMSc Henning Beck-Nielsen, DMSc 1 Department of Endocrinology, Department of Endocrinology, Odense University Hospital, Odense, Denmark. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.91 Open the PDF Link PDF for Case 91: Treatment of a Patient with Diabetes and Severe Hypoglycemia in another window
• Case 92: Hypoglycemia with Use of Glargine Insulin in the Management of Type 2 Diabetes, Occurring with Titration Aimed at Achieving Prebreakfast Glucose Levels <100 mg/dL (5.6 mmol/L) By Saira Adeel, MD ; Saira Adeel, MD 1 Atlanta VA Medical Center, Division of Endocrinology, Emory University School of Medicine, Atlanta, GA. Search for other works by this author on: This Site PubMed Google Scholar Lawrence S. Phillips, MD Lawrence S. Phillips, MD 2 Division of Endocrinology and Metabolism, Emory University, Atlanta, GA. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.92 Open the PDF Link PDF for Case 92: Hypoglycemia with Use of Glargine Insulin in the Management of Type 2 Diabetes, Occurring with Titration Aimed at Achieving Prebreakfast Glucose Levels &lt;100 mg/dL (5.6 mmol/L) in another window
• Case 93: Progressive Hypoglycemia Due to Insulinoma in a Patient with Type 2 Diabetes: Treatment with Image-Guided Minimally Invasive Pancreas-Sparing Surgery By Mary-Elizabeth Patti, MD ; Mary-Elizabeth Patti, MD 1 Joslin Diabetes Center, Boston, MA. 5 Harvard Medical School, Boston, MA. Search for other works by this author on: This Site PubMed Google Scholar Mark P. Callery, MD, FACS ; Mark P. Callery, MD, FACS 2 Institute for HepatoBiliary and Pancreatic Surgery, Beth Israel Deaconess Medical Center, Boston, MA. 5 Harvard Medical School, Boston, MA. Search for other works by this author on: This Site PubMed Google Scholar Robert M. Najarian, MD ; Robert M. Najarian, MD 3 Department of Pathology, Beth Israel Deaconess Medical Center, Boston, MA. 5 Harvard Medical School, Boston, MA. Search for other works by this author on: This Site PubMed Google Scholar Mandeep S. Sawhney, MD, MS ; Mandeep S. Sawhney, MD, MS 4 Department of Medicine, Beth Israel Deaconess Medical Center and Dana Farber Harvard Cancer Center, Boston, MA. 5 Harvard Medical School, Boston, MA. Search for other works by this author on: This Site PubMed Google Scholar Lyle Mitzner, MD ; Lyle Mitzner, MD 1 Joslin Diabetes Center, Boston, MA. 5 Harvard Medical School, Boston, MA. Search for other works by this author on: This Site PubMed Google Scholar Allison B. Goldfine, MD ; Allison B. Goldfine, MD 1 Joslin Diabetes Center, Boston, MA. 5 Harvard Medical School, Boston, MA. Search for other works by this author on: This Site PubMed Google Scholar A. James Moser, MD, FACS A. James Moser, MD, FACS 2 Institute for HepatoBiliary and Pancreatic Surgery, Beth Israel Deaconess Medical Center, Boston, MA. 5 Harvard Medical School, Boston, MA. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.93 Open the PDF Link PDF for Case 93: Progressive Hypoglycemia Due to Insulinoma in a Patient with Type 2 Diabetes: Treatment with Image-Guided Minimally Invasive Pancreas-Sparing Surgery in another window
• Case 94: Managing Pain and Paralysis in Chronic Inflammatory Demyelinating Polyneuropathy in Diabetes By Aaron I. Vinik, MD, PhD, FCP, MACP, FACE Aaron I. Vinik, MD, PhD, FCP, MACP, FACE 1 Eastern Virginia Medical School, Strelitz Diabetes Center, Norfolk, VA. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.94 Open the PDF Link PDF for Case 94: Managing Pain and Paralysis in Chronic Inflammatory Demyelinating Polyneuropathy in Diabetes in another window
• Case 95: Neuropathy in Metformin-Treated Type 2 Diabetes By Aaron I. Vinik, MD, PhD, FCP, MACP, FACE Aaron I. Vinik, MD, PhD, FCP, MACP, FACE 1 Eastern Virginia Medical School, Strelitz Diabetes Center, Norfolk, VA. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.95 Open the PDF Link PDF for Case 95: Neuropathy in Metformin-Treated Type 2 Diabetes in another window
• Case 96: A Case of Acute Sensory Neuropathy in Type 1 Diabetes By Andrew J.M. Boulton, MD, DSc, FACP, FRCP Andrew J.M. Boulton, MD, DSc, FACP, FRCP 1 University of Manchester, UK; University of Miami, Miami, FL; Manchester Royal Infirmary, Manchester, UK; President, European Association for the Study of Diabetes, Dusseldorf, Germany. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.96 Open the PDF Link PDF for Case 96: A Case of Acute Sensory Neuropathy in Type 1 Diabetes in another window
• Case 97: Nondiabetic Neuropathy in a Patient with Type 2 Diabetes By David S.H. Bell, MB David S.H. Bell, MB 1 University of Alabama, Birmingham, AL. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.97 Open the PDF Link PDF for Case 97: Nondiabetic Neuropathy in a Patient with Type 2 Diabetes in another window
• Case 98: Severe Distal Symmetrical and Autonomic Neuropathy in a Patient with a Short Duration of Type 1 Diabetes By David S.H. Bell, MB David S.H. Bell, MB 1 University of Alabama, Birmingham, AL. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.98 Open the PDF Link PDF for Case 98: Severe Distal Symmetrical and Autonomic Neuropathy in a Patient with a Short Duration of Type 1 Diabetes in another window
• Case 99: Diabetic Amyotrophy and Neuropathic Cachexia By David S.H. Bell, MB David S.H. Bell, MB 1 University of Alabama, Birmingham, AL. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.99 Open the PDF Link PDF for Case 99: Diabetic Amyotrophy and Neuropathic Cachexia in another window
• Case 100: High GAD Antibody Levels and Cerebellar Atrophy in a Patient with Type 1 Diabetes By David S.H. Bell, MB David S.H. Bell, MB 1 University of Alabama, Birmingham, AL. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.100 Open the PDF Link PDF for Case 100: High GAD Antibody Levels and Cerebellar Atrophy in a Patient with Type 1 Diabetes in another window
• Case 101: Resolution of Infertility with Diabetes Therapy By David S.H. Bell, MB David S.H. Bell, MB 1 University of Alabama, Birmingham, AL. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.101 Open the PDF Link PDF for Case 101: Resolution of Infertility with Diabetes Therapy in another window
• Case 102: The Initial Pregnancy Visit of a Woman with Type 1 Diabetes and Diabetes Complications By Aidan McElduff, MD Aidan McElduff, MD 1 Discipline of Medicine, Sydney University, Sydney, NSW, Australia. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.102 Open the PDF Link PDF for Case 102: The Initial Pregnancy Visit of a Woman with Type 1 Diabetes and Diabetes Complications in another window
• Case 103: Gastroparesis and Pregnancy By Carl Peters, MB, ChB ; Carl Peters, MB, ChB 1 Newcastle Magnetic Resonance Centre, Campus for Ageing and Vitality, Newcastle upon Tyne, England. Search for other works by this author on: This Site PubMed Google Scholar Roy Taylor, MD Roy Taylor, MD 1 Newcastle Magnetic Resonance Centre, Campus for Ageing and Vitality, Newcastle upon Tyne, England. Search for other works by this author on: This Site PubMed Google Scholar Doi: https://doi.org/10.2337/9781580405713.103 Open the PDF Link PDF for Case 103: Gastroparesis and Pregnancy in another window
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