stem cell therapy research paper

Current state of stem cell-based therapies: an overview. Recent research reporting successful translation of stem cell therapies to patients have enriched the hope that such regenerative strategies may one day become a treatment for a wide range of vexing diseases. In fact, the past few years witnessed, a rather exponential advancement in ...

Stem Cell Research & Therapy is the major forum for translational research into stem cell therapies. An international peer-reviewed journal, it publishes high-quality open access research articles with a special emphasis on basic, translational and clinical research into stem cell therapeutics and regenerative therapies, including animal models and clinical trials.

In recent years, stem cell therapy has become a very promising and advanced scientific research topic. The development of treatment methods has evoked great expectations. This paper is a review focused on the discovery of different stem cells and the potential therapies based on these cells. The genesis of stem cells is followed by laboratory steps of controlled stem cell culturing and derivation.

The discovery of hPSCs, including human embryonic stem cells (hESCs) and human induced pluripotent stem cells (hiPSCs), has revolutionized stem cell research and cell-based therapy. 98 hESCs were ...

From 1971 to 2021, 40,183 research papers were published regarding stem-cell-based therapies. All of these studies were conducted around discoveries and for the goal of "Stem Cell Therapy" based on the therapeutic efficacy of stem cells . As basic stem cell research has soared over the past few years, "translation research", a ...

In recent years, stem cell therapy has become a very promising and advanced scientific research topic. The development of treatment methods has evoked great expectations. This paper is a review focused on the discovery of different stem cells and the potential therapies based on these cells. The genesis of stem cells is followed by laboratory ...

In the study published by Sun et al., a systematic review and meta-analysis illustrated the advantageous of stem cell therapy in diabetic foot and can improve the quality of life of patients. Nevertheless, the... Yan Bai and Fan Zhang. Stem Cell Research & Therapy 2024 15 :85.

Stem Cell Research & Therapy (2023) Despite many reports of putative stem-cell-based treatments in genetic and degenerative disorders or severe injuries, the number of proven stem cell therapies ...

Abstract. Stem cells offer new therapeutic avenues for the repair and replacement of damaged tissues and organs owing to their self-renewal and multipotent differentiation capabilities. In this paper, we conduct a systematic review of the characteristics of various types of stem cells and offer insights into their potential applications in both ...

Articles on embryonic stem cells dominated newspaper reports on stem-cell therapy for over a decade (1998-2010) and often positioned induced pluripotent stem cells as an 'ethical ...

Stem cell therapy is a novel therapeutic approach that utilizes the unique properties of stem cells, including self-renewal and differentiation, to regenerate damaged cells and tissues in the human body or replace these cells with new, healthy and fully functional cells by delivering exogenous cells into a patient. 7 Stem cells for cell-based ...

2 Global Institute of Stem Cell Therapy and Research, 4660 La Jolla Village Drive, San Diego, CA 92122, United States. ... Results: Remarkable progress in stem cell research has established that the cell-based therapy could be an option for treating diseases which could not be cured by conventional medical means till recent. Stem cells play ...

Within these diseases a genetic defect or defects prevents the proper function of cells derived from the hematopoietic stem cell lineage. Treatment includes implantation of genetically normal cells from a healthy donor to serve as a lifelong self-renewing source of normally functioning blood cells. ... Stem Cell Research and Therapy. 2018;9(1 ...

In the last 50 years, more than 40,000 research papers have focused on stem-cell-based therapies. In this review study, we present a general overview of the translation of stem cell therapy from scientific ideas to clinical applications. ... Hang-Soo Park, Farzana Begum Liakath Ali, and Ayman Al-Hendy. 2022. "Stem Cell Therapy: From Idea to ...

Stem Cell Research and Therapy had the most articles, totaling 33. Stem Cell Reviews and Reports ranked second, with 23 papers. The third was Frontiers in Immunology, with 25 papers. The following journals were International Journal of Molecular Sciences and Cells, with 20 and 18 papers, respectively. These journals are mainly focused on cell ...

Abstract and Figures. Stem cells are defined as cells that have clonogenic and self-renewing capabilities and differentiate into multiple cell lineages. Stem cells are found in all of us, from the ...

Stem cell research holds tremendous promise for the development of novel therapies for many serious diseases and injuries. While, stem cell based treatments have been established as a clinical ...

Stem cells: past, present, and future Wojciech Zakrzewski1*, Maciej Dobrzyński2, Maria Szymonowicz1 and Zbigniew Rybak1 Abstract In recent years, stem cell therapy has become a very promising and advanced scientific research topic. The development of treatment methods has evoked great expectations. This paper is a review focused on the

From 1971 to 2021, 40,183 research papers were published regarding stem-cell-based therapies. All of these studies were conducted around discoveries and for the goal of "Stem Cell Therapy" based on the therapeutic efficacy of stem cells [27]. As basic stem cell research has soared over the past few years, "translation research", a ...

Research article Open access LCN2 Inhibits the BMP9-induced Osteogenic Differentiation through Reducing Wnt/β-catenin Signaling via Interacting with LRP6 in Mouse Embryonic Fibroblasts Jin-Hai Jiang, Shi-Yu Wang, Jie Zhang, Hang Liu, ...

Introduction to Stem Cell Therapy. Stem cells have the ability to differentiate into specific cell types. The two defining characteristics of a stem cell are perpetual self-renewal and the ability to differentiate into a specialized adult cell type. There are two major classes of stem cells: pluripotent that can become any cell in the adult ...

ROCHESTER, Minn. — A Mayo Clinic study shows stem cells derived from patients' own fat are safe and may improve sensation and movement after traumatic spinal cord injuries.The findings from the phase 1 clinical trial appear in Nature Communications.The results of this early research offer insights on the potential of cell therapy for people living with spinal cord injuries and paralysis for ...

Stem Cell Research & Therapy aims to be the major forum for translational research into stem cell therapies. The journal has a special emphasis on basic, translational, and clinical research into stem cell therapeutics, including animal models, and clinical trials. Stem cell research for therapeutic purposes has largely used adult stem cell ...

The findings from the Phase I clinical trial appear in Nature Communications in the paper, ... Stem cells are used mainly in research in the U.S., and fat-derived stem cell treatment for spinal ...

Stem cells are used mainly in research in the U.S., and fat-derived stem cell treatment for spinal cord injury is considered experimental by the Food and Drug Administration.

The current pressing need for a treatment for (AD) and advances in the field of cell therapy, has rendered stem cell therapeutics a promising field of research. Despite advancements in stem cell technology, confirmed by encouraging pre-clinical utilization of stem cells in AD animal models, the number of clinical trials evaluating the efficacy ...

However, research on stem cell therapy for human ED is still limited. This article summarizes the recent literature on basic stem cell research on ED, including cavernous nerve injury, aging, diabetes, and sclerosing penile disease, and describes mechanisms of action and therapeutic effects of various stem cell therapies in experimental animals.

Despite of rapid advancement in research of diagnostics and therapeutics, the death rate by cancer only declined ~1.5% annually in the period of 2006-2015 in United States . Comprehensive knowledge about cancer biology would allow scientists to design better therapeutic systems. ... Meanwhile, stem cell therapy, which involves all procedures ...

Reprogramming technology is considered one of the most important advances in the field of stem cell research and regenerative medicine [14, 19, 20].Fibroblasts were the first somatic cells to be applied for reprogramming into human and mouse iPSCs [21, 22].Subsequently, more and more cell types from patients were identified to induce iPSCs, like peripheral blood mononuclear cells (PBMCs ...