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Pathology Thesis Topics for MD/DNB

Below is the list of 100 free thesis topics for MD/DNB Pathology. You can select any good Pathology thesis topics for MD/DNB from here. For more thesis topics you can avail the service of premium thesis topics. The premium thesis topics include list of 2000+ Pathology thesis topics as well as recent topics which has been published in various national and international Pathology journals. 

• A Clinical, Endoscopic and Histomorphological evaluation of Esophageal Lesions
• A Clinical, Cytological, Histomorphological evaluation of Lymphnodes in Children
• Histopathological analysis of prostatic lesions and the assessment of prognosis with immunohistochemistry
• A Clinico pathological correlation and analysis of ovarian tumours with study of expression pattern of Pankeratin
• The value of AgNOR study in radiotherapy treated squamous cell carcinoma of the cervix – As a diagnostic and prognostic marker
• A Clinical histomorphological and Immunohistochemical analysis of breast neoplasms
• A Clinical, Endoscopic and Histomorphological Evaluation of Esophageal Lesions
• A Clinical and Histomorphological Analysis of Paediatric Malignant Neoplasms
• Histo Pathological Analysis of Central Nervous System Neoplasms
• Helicobacter pylori related gastritis in adults a clinical, endoscopic
• Fine needle aspiration cytology and histopathological correlation of nodular lesion of thyroid with immunohistochemical study
• Histopathological analysis of prostatic lesions and role of p63 versus high molecular weight cytokeratin in distinguishing prostatin
• Histopathological analysis and p53 expression in intestinal tumors
• Clinicopathological analysis of ovarian tumors and the role of p53 and Ki- 67 in surface epithelial tumors of ovary
• Histopathological analysis and Ki- 67 expression in various central nervous system tumors
• Role of Mucin histochemistry and immunohistochemistry in gastric adenocarcinoma
• Correlation of ER, PR AND HER-2/neu with histological variants of breast carcinoma
• Anaemia in Nonhaematological Malignancies – A Descriptive Study
• Mycotic Lesions in Surgical Pathology
• The role of pap smear in detection of cytological abnormalities of uterine cervix in hiv infected women
• Haematological profile in the differential diagnosis of microcytic hypochromic anaemia in children
• A study of distribution of p53, cyclin d1 and cd44 in oral squamous cell carcinoma
• Histopathological spectrum of ovarian tumors: a descriptive study
• A study of trucut biopsies of hepatic lesions with special reference to immunohistochemistry and special stain
• Study of silver staining of nucleolar organiser regions in malignancies of uterine cervix
• A correlative study on bone marrow angiogenesis with bone marrow fibrosis and spleenomegaly
• Expression of bcl-2 and ki-67 in endometrial lesions
• The expression and diagnostic utility of amacr and 3 in
• Cytological grading of ductal carcinoma of breast in fine needle aspirates and its correlation with histological grading
• Diagnostic utility of squash cytology and its correlation with histopathology in neuropathological specimen
• Placental pathology in low birth weight live births.
• Utility of RBC histograms in various types of anaemia in pediatric age group ( 1 – 18 years).
• Prevalence of anemia in Geriatric population.
• Comparison of digital vs manual assessment of  Ki67 in breast carcinoma patients : A hospital based study.
• Detection of human papilloma virus infection in cases of oral arcinoma using P16 immunohistochemistry.
• The distribution of mast cells in uterine leiomyoma – A hospital based observational study.
• Prevalence of congenital anomalies in fetuses subjected for autopsy – a hospital based cross sectional study.
• Prevalence of thrombocytopenia in pregnancy – A hospital based study.
• Correlation of blood parameters with outcome in covid 19 positive patients.
• Estimating prevalence of SOX – 2 expression in cervical squamous carcinomas – A hospital based cross sectional study.
• Correlation of FNAC and histopathology in the diagnosis of head and neck lesions.
• Assessment of coagulation Parameters in Covid 19 patients – A cross sectional study.
• Hematological and Biochemical Profile of Children below 5 years of age, suspected with hemolytic anemia – A hospital based observational study.
• A Comparative study of hematological and inflammatory markers in preterm labour and term labour.
• A Study of morphological abnormalities in placenta associated with fetal death and still birth – A hospital based observational study.
• Conventional Papanicolou (PAP) stain vs Rehydrated air dried pap stain (RADPS) vs Rapi9d Economical Acetic acid pap stain (REAP) on vaginal smears: An observational study.
• Study of ki67 expression in oral and oropharyngeal Squamous cell carcinoma.
• Comparative study of peripheral smear with RBC indices and RBC histograms incases of anemia in adults.
• Evaluation of CD10 Biomarker Expression in Diagnosis of Colorectal Carcinoma – A One year Cross Sectional Study .
• Evaluation of Derived Indices of Peripheral Whole Blood Cell Counts in Non-Dialysis CKD patients – One year cross sectional study in a tertiary care hospital.
• Histopathological spectrum of upper gastrointestinal tract lesions in patients undergoing upper gastrointestinal endoscoic biopsies.
• Expression of Vimentin as a merker of epithelial – mesenchymal transition in invasive breast carcinoma : A Hospital Based Study.
• Ki67 as a diagnostic indicator in differentiating psoriasis from psoriasiform dermatitits – A hospital based study.
• Study of Dermal Vascular Changes in Psoriasis – An Observational Study.
• Evaluation of Haematological and Biochemical parameters in Chronic Liver Disease patients
• Comparison of the Neutrophil – Lymphocyte, Platelet-Lymphocyte and Monocyte-Lymphocyte ratios in schizophrenic patients with healthy individuals: A cross sectional study.
• Clinical and diagnostic markers in patients with pregnancy induced hypertension- hospital based observational study.
• Diagnostic utility of cell block method versus conventional smear study in pleural & peritoneal fluid cytology
• Evaluation of Role of GATA3 expression in differentiating urothelial carcinomas from adenocarcinomas of prostate.
• The role of p-STAT3 in cervical intra epithelial neoplasia and squamous cell carcinoma.
• Diagnostic utility of TROP – 2 expression in Benign and malignant lesions of thyroid.
• Evaluation of expression of immunohitsochemical (IHC) markers High Molecular weight cytokeratin (HMWCK) and Alpha – methylacyl coA racemose (AMACR) in prostatic needle biopsies and transurethral re-section of prostate (TURP) specimen – a one year observational study.
• Histopathological evaluation to compare the diagnostic accuracy of pipelle’s  endometrial sampling with conventional D & C in patient with AUB.
• Histopathological study and Immunohistochemical expression of EGFR in lung tumours.
• Study of Immunohistochemical expression of AKT (Protein kinase B) in prostatic adenocarcinoma – A descriptive study.
• To study CD64 expression on neutrophil by Flow cytometry as novel biomarker in early diagnosis of  sepsis (as compare to ESR, CRP & Blood culture).
• Ki-67 Expression in endometrial hyperplasia and endometrial carcinoma – an observational study.
• Identification of Lymphatic Invasion in Breast Carcinoma patients using immunomarker D2-40 – A one year cross sectional study in a tertiary care centre of Belagavi.
• Evaluation of Immunohistochemical expression of COX – 2 in breast carcinoma patients – A hospital based study .
• Immunohistochemical expression of   P 16INK4a in patients with squamous cell carcinoma of the cervix – A one year retrospective and prospective study intertiary care hospital.
• To correlate immunohistochemistry of BRCA1 and BRCA2 in breast carcinoma – cross sectional study .
• Expression of Prostate specific membrane antigen in breast cancer patients attending tertiary care hospital – A one year cross sectional study.
• Role of clinicohaematological profile in diagnosis of dengue – One year hospital based observational study .
• Comparision of fluorescent staining and conventional staining of skin biopsy in diagnosis of leprosy – A hospital based study .
• A comparative study to know the haematological profile and Biochemical profile among children with severe acute malnutrition and healthy children .

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2024 Q&A with the Neuroscience PhD Program graduates

2024 commencement. Back (L to R): Julian Bieber-Dishart, Marisa Denkinger, Katie Cording, Jacob Ziontz. Front: Xue Lily Gong, Hayley Bounds, Erin Aisenberg, Madeline Klinger, Professor Frédéric Theunissen. Photo by  GradImages

Congratulations to our recent and upcoming Neuroscience PhD Program graduates: Matthew Davis, Erin Aisenberg, Katie Cording, Marisa Denkinger, Julian Bieber-Dishart, Xue Lily Gong, Madeline Klinger, Sylvia Madhow, Hayley Bounds, and Jacob Ziontz!

Read our Q&A below with some of the graduates to learn about their most interesting discoveries, future plans, and words of advice.

Erin Aisenberg, Bateup lab

Thesis: Elucidating a Novel Peptidergic Circuit in the Nucleus Accumbens Medial Shell

What is the most interesting thing you discovered in your research here.

When I set out on my project I was interested in looking at the role of GRP-GRPR (gastrin-releasing peptide-GRP receptor) signaling in the nucleus accumbens medial shell. However, as I was doing so, I discovered that the receptor-expressing cells represented a novel subpopulation of striatal projection neurons that had previously never been classified with unique electrophysiological properties.

What are you doing next?

I will be staying on as a postdoc in the Bateup lab to finish my paper.

Do you have any advice for incoming or current students?

There is always going to be more to do, so make sure to set boundaries and take time away from the lab. Also, you will fail a lot during your PhD, so try not to be too hard on yourself.

Julian Bieber-Dishart, Dillin lab

Thesis: olfaction regulates peripheral mitophagy and mitochondrial function .

We were fascinated to learn that the olfactory nervous system instructs peripheral tissues to perform mitophagy, limiting mitochondrial iron stores from invading pathogens, and conferring a pathogen resistance phenotype. Altogether, our research shows that the olfactory nervous system evolved to anticipate pathogenic infection, and prime the organism to withstand pathogenic insult.

I'll be venturing into the intellectual property law field.

Take advantage of the wide world of UC Berkeley! Explore classes outside of neuroscience and in other schools, and attend career panels. You never know what might interest you.

Hayley Bounds, Adesnik lab  

Thesis: causally connecting cortical codes to visual perception.

I used new 2-photon optogenetics to target and activate individual neurons in the brain while mice performed a visual task. I learned that the neurons that we thought would be the most involved in allowing mice to detect hard to see stimuli, that is, the neurons that respond strongly to that stimulus, were no more involved than any other neuron was.

I'll be starting my postdoc in the Losonczy Lab at Columbia, studying place coding in the hippocampus.

Make sure you really care about answering the questions your project(s) are asking — you're going to be working on them for a long time, even if it's only a subproject, and without that drive it's hard to stay motivated.

Katie Cording, Bateup lab

Thesis: the impact of autism spectrum disorder risk gene mutations on striatal circuit function.

In my research I studied two different genetic mouse models of autism spectrum disorder. Despite having different genetic mutations and physiological changes, both models exhibited the same overall circuit change in a subregion of the striatum, a subcortical region involved in action selection and motor learning. Both models also exhibited increased performance in a motor learning task. It was very cool to find that convergence of circuit and behavior change arising from different genetic manipulations.

I'll be finishing up my project as a postdoc in the Bateup lab, and then I'll likely pursue research in industry.

Try to remember and find the joy and excitement of research when things are tough. We're pursuing knowledge for knowledge's sake, and that's really cool! I think sometimes this means not taking things too seriously, learning how to walk away and take a breather when something isn't working, and having hobbies, passions and friends outside of lab that keep you refreshed and ready to get back into work the next day. 

Marisa Denkinger, Jagust lab

Thesis: Relationships between blood-brain barrier disruption and Alzheimer's disease biomarkers in aging

My research used multimodal neuroimaging methods to investigate whether there is a relationship between neurovascular dysfunction, in particular blood-brain barrier disruption, Alzheimer's disease (AD) biomarkers, and cognition during normal aging. The most interesting discovery from my dissertation was that blood-brain barrier disruption selectively affects memory performance, and this impact depends on the extent of atrophy observed. Importantly, this relationship does not depend on global amyloid beta and regional tau levels. These results suggest  that in normal aging, where there may not be substantial AD pathology, having greater blood-brain barrier disruption and atrophy may have an impact on memory performance.

I am currently exploring options for postdoctoral fellowships, focused on aging and Alzheimer's disease in Phoenix, Arizona.

My advice for incoming students is to prioritize a healthy work-life balance. Getting a PhD is a long road and it is super important to take care of yourself, so that you can achieve your research goals!

Xue Lily Gong, Theunissen and Gallant labs

Thesis: language representation in human cerebral cortex, what is the most interesting thing you discovered in your research here .

Brain representation of language is far more "messy" than I initially anticipated. Rather than being neatly organized to specific cortical regions, it involves complex and simultaneous representing and integrating of multiple levels of information.

Postdoc in UCSF.

When selecting a lab to join during my first year, I followed advice that prioritized Professor > People > Project. I believe this is also applicable to my PhD journey. I chose professors whom I admire and see as my mentors, someone I want to become. I surrounded myself with colleagues, aiming to build lifelong friendships and collaborations. The project I ended up working with has grown into a topic that motivates my future research.

To me, the PhD journey is inherently nonlinear and highly personalized, presenting unique challenges to each one. My experience in the Neuroscience PhD Program taught me the importance of seeking help when needed. The community here is incredibly supportive, always ready to assist in any aspect of both academic and personal challenges.

My PhD did not start as I had envisioned; it was filled with unexpected twists that were truly mind-blowing. However, it concluded much better than I expected, which was a pleasant surprise, though I believe I would have been happy regardless. This experience has made me more resilient and mature in all aspects. I sincerely hope all of you will have a fulfilling journey in the Neuroscience PhD Program.

Madeline Klinger (she/her), Wilbrecht and Landry labs

Thesis: fluorescent adolescence: shedding light on neural encoding of task information in the adolescent vs. adult frontal cortex.

Adolescent mice are actually quite good at an inhibitory control task, despite pop science maligning adolescents as "impulsive". In the case of my task, being a little "impulsive" actually seemed to help adolescents better sample and understand their environment, and they learned faster than adults. Neurons in layer 2/3 of the adolescent dorsomedial prefrontal cortex (dmPFC) also contained more decodable information about task variables than the adult dmPFC.

Catching up on artistic endeavors I've put on hold, while also applying for positions as a program manager or program officer at funding institutions. My career goal is to help guide neuroscience toward a more equitable research practice.

Figure out your work style and what you need from a mentor to succeed. Come up with agreements and clear expectations between yourself, your mentor, and your lab. Be proactive about asking for help and meetings. Advocate for your needs, and prioritize your mental health!

Sylvia Madhow,  Bouchard lab

Thesis: parsimonious estimates of functional connectivity and biomarkers of cognitive development in early childhood.

My work was in predictive modeling of cognition and behavior from brain data. I found that modeling temporal dependence in brain activity produces sparse and graphically efficient connectomes, but that we still have a long way to go before our approach can accurately and consistently predict cognitive development. Above all, I gained new appreciation for the importance of interpretability in predictive modeling — all the accuracy in the world is of little consequence without a deep understanding of the underlying data. Also, always sing to your rats — they don't criticize even when you're flat.

If the past few weeks are any indication, I'll be sketching a lot, muttering to myself, and dipping my toes in the ocean.

It's so easy to get impatient with yourself and become preoccupied with perceived shortcomings. Give yourself the time and grace to learn. 

Jacob Ziontz,  Jagust lab

Thesis: functional networks in aging and alzheimer's disease: contributions and consequences.

In the aging brain, how strongly connected different regions are is closely associated with the spread of neuropathology between these regions. This represents not only a potential way to predict where and how quickly pathology will spread, but also how the connectivity profile of different brains may influence the specific cognitive deficits that individuals experience as they age.

I'm starting a postdoc at UCSF with Drs. Renaud La Joie and Gil Rabinovici studying clinical dementia phenotypes, distribution of Alzheimer's tau pathology, and brain connectivity.

One of the most critical parts of your PhD training is learning how to think like a scientist. While you build research skills and collect data, don't forget that thinking about science is important and hard work and you should reward yourself for doing it!

View all Neuroscience PhD Program graduate Q&As.

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Friday 25 September 2015

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