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The Royal Society of Chemistry’s Journals

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Current journals

  • Analyst 1876 - Present
  • Analytical Methods 2009 - Present
  • Biomaterials Science 2013 - Present
  • Catalysis Science & Technology 2011 - Present
  • Chemical Communications 1996 - Present
  • Chemical Science 2010 - Present
  • Chemical Society Reviews 1972 - Present
  • Chemistry Education Research and Practice 2000 - Present
  • CrystEngComm 1999 - Present
  • Dalton Transactions 2003 - Present
  • Digital Discovery 2022 - Present
  • EES Catalysis 2023 - Present
  • Energy & Environmental Science 2008 - Present
  • Energy Advances 2022 - Present
  • Environmental Science: Advances 2022 - Present
  • Environmental Science: Atmospheres 2021 - Present
  • Environmental Science: Nano 2014 - Present
  • Environmental Science: Processes & Impacts 2013 - Present
  • Environmental Science: Water Research & Technology 2015 - Present
  • Faraday Discussions 1991 - Present
  • Food & Function 2010 - Present
  • Green Chemistry 1999 - Present
  • Industrial Chemistry & Materials 2023 - Present
  • Inorganic Chemistry Frontiers 2014 - Present
  • Journal of Analytical Atomic Spectrometry 1986 - Present
  • Journal of Materials Chemistry A 2013 - Present
  • Journal of Materials Chemistry B 2013 - Present
  • Journal of Materials Chemistry C 2013 - Present
  • Lab on a Chip 2001 - Present
  • Materials Advances 2020 - Present
  • Materials Chemistry Frontiers 2017 - Present
  • Materials Horizons 2014 - Present
  • Molecular Omics 2018 - Present
  • Molecular Systems Design & Engineering 2016 - Present
  • Nanoscale 2009 - Present
  • Nanoscale Advances 2018 - Present
  • Nanoscale Horizons 2016 - Present
  • Natural Product Reports 1984 - Present
  • New Journal of Chemistry 1998 - Present
  • Organic & Biomolecular Chemistry 2003 - Present
  • Organic Chemistry Frontiers 2014 - Present
  • Physical Chemistry Chemical Physics 1999 - Present
  • Polymer Chemistry 2010 - Present
  • Reaction Chemistry & Engineering 2016 - Present
  • RSC Advances 2011 - Present
  • RSC Applied Interfaces 2023 - Present
  • RSC Applied Polymers 2023 - Present
  • RSC Chemical Biology 2020 - Present
  • RSC Mechanochemistry 2024 - Present
  • RSC Medicinal Chemistry 2020 - Present
  • RSC Pharmaceutics 2024 - Present
  • RSC Sustainability 2023 - Present
  • Sensors & Diagnostics 2022 - Present
  • Soft Matter 2005 - Present
  • Sustainable Energy & Fuels 2017 - Present
  • Sustainable Food Technology 2023 - Present

About our journals

The Royal Society of Chemistry publishes 56 peer-reviewed journals that cover the core chemical sciences including related fields such as biology, biophysics, energy and environment, engineering, materials, medicine and physics.

Chemical Society Reviews journal

Open access

All of our journals offer authors the option to choose an open access licence. In addition to our subscription journals, where authors can also publish through the traditional route, we have a growing number of fully open access journals.

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  • ACS Publications

28 Must-Read Topics in Chemistry

  • Mar 4, 2021
  • 14 min read

ACS Publications regularly produces collections of the most important chemistry research topics. These Virtual Collections of the most important chemistry research topics bring together the most important ideas in the field in a variety of ways, including Special Issues and ACS Selects from across the portfolio journals. These collections reflect the most important chemistry research […]

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ACS Publications regularly produces collections of the most important chemistry research topics. These Virtual Collections of the most important chemistry research topics bring together the most important ideas in the field in a variety of ways, including Special Issues and ACS Selects from across the portfolio journals. These collections reflect the most important chemistry research topics of current scientific interest and are designed for experienced investigators and educators alike.

Browse 28 of the most important, engaging topics in chemists with Virtual Collections released by ACS Publications journals in Q4 2020:

Crystalline molecular materials: from structure to function.

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This Virtual Special Issue focuses on the design and study of materials wherein the target properties arise from, or are enhanced by, the three-dimensional assembly of molecules in a solid phase. The “structure−function” relationship transcends the nature of the individual molecule, and supramolecular organization is a key component in the material’s properties. The goal of this issue is to assemble contributions from a broad community of scientists with similar research interests, as defined by the need to understand and manipulate the bulk assembly of molecules. Placing emphasis on a common interest in supramolecular architecture, this issue showcases work in apparently disparate fields, including molecule-based magnetism, rare zero thermal expansion properties, and catalytic activity.

Read the Issue. ***

Materials for Thermoelectric Energy Conversion

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This virtual issue of ACS Applied Materials & Interfaces and ACS Applied Energy Materials presents cutting edge articles in the field of Thermoelectric Energy Conversion. Thermoelectric materials and devices are central for energy conversion and management as they convert waste heat into electricity. Given the ubiquitous nature of heat, thermoelectric materials provide total-package solutions to mitigate environmental crisis and energy needs. The realization of this has caused a surge in the development of high-performance, environmentally benign, robust, and earth-abundant inorganic materials, which can be used in heat to electrical energy generations in power plants, space, automobiles, households, battery technology, and data centers. Interestingly, flexible thermoelectric materials, mainly based on organic/polymer materials, have successfully been integrated into body-worn fabrics and watches, which simply utilize body heat to generate electricity. Furthermore, using the Peltier effect, thermoelectric coolers are developed and are one of the mainstays in the consumer market for refrigeration purposes, especially for portable applications. Hence, thermoelectricity is foreseen as a potential frontrunner in energy management for the near future.

Interfacialscience Developments at the Chinese Academy of Sciences

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This virtual issue is a sampling of some of the most recent work from the Chinese Academy of Sciences, with an emphasis on work from this year (2020) so far. The 46 articles in this virtual issue cover a broad range of research topics, examples of which include Janus particle engineering and interfacial assembly, surface modification of colloid particles, stability of water monolayer in mineral under high pressure, nano-bubbles adsorption on surface, switching of underwater superhydrophilicity and superoleophobicity, nanostructured de-icing surface, lithium ion battery anode binder, bio-inspired smart liquid directional transport control, corrosion resistance of alloys, behavior of polymers at solid/liquid interface, and effect of polymer conformation on protein resistance.

Celebrating 90% Completion of the Human Proteome

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Twenty years after the establishment of the international Human Proteome Organization (HUPO) and ten years after its launch of the Human Proteome Project (HPP), researchers have much to celebrate. Today, HUPO will release the draft human proteome at the 19th Human Proteome Organization World Congress, connecting virtually, with this Virtual Issue published in the Journal of Proteome Research.

Read the Issue . ***

Nanomaterials-based Membranes for Chemical Separations

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Membranes are a critical area of research in academia and have been used in industrial applications for decades. Membrane-based separations are desired in industry because they can be highly energy efficient and up to an order of magnitude less expensive than other techniques such as distillation. In addition, these separations are easily scaled to industrial levels so that advances in the laboratory can be translated to real applications. The key challenges in this field are how to separate chemicals with similar sizes by having a high flux for only one chemical through a membrane. This difference in flux should translate into a high selectivity for one chemical over one or more other chemicals present in a mixture. An unfortunate trade-off in membrane-based separations is that as the permeation of a chemical increases, the selectivity of the membrane will often decrease. To address these challenges, scientists often use cross-linked polymers with ill-defined pores, hard materials such as zeolites with well-defined pores, 2D materials, coated nanofibers, carbon nanotubes, metal nanoparticles, or other nanomaterials.

Organic Chemistry in China: Synthetic Methodology, Natural Products, and More

During the past 20 years, China has become a powerhouse in chemistry research, now leading globally in submissions of research articles to chemical journals. In recognizing these developments, Organic Letters presents a Virtual Issue that includes a collection of 25 research articles contributed by Chinese chemists during 2019-2020, selected from among the more than 1,000 articles published in the journal from China over this period.

Advances in Microfluidics Research

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This Virtual Issue highlights articles published in Analytical Chemistry that showcase advances in microfluidics research over the past several years. The articles below are separated by sub-field and span research on virus detection to cell manipulation to 3D-printing, and are all at the cutting edge of microfluidics technologies. The thirty articles included in this collection were selected by Associate Editor Yoshinobu Baba and include previous winners of the Chemical & Biological Microsystems Society (CBMS)/ Analytical Chemistry co-sponsored Young Innovator Award.

Chemistry in Korea: IBS and Beyond

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This virtual issue of “Chemistry in Korea: IBS and Beyond” highlights the latest contributions from eight IBS centers along with exciting advances from other emerging scientists in South Korea. Topics encompass a wide range of chemistry and its cross-boundary researches from theory and simulations, nanomaterials, molecular synthesis, catalysts, spectroscopy, supramolecular chemistry, soft materials to nanomedicine.

Highlighting Analytical Chemistry 2020 Advisory Board Members

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The members of Analytical Chemistry ‘s Editorial Advisory Board (EAB) and Early Career Board (ECB) panels devote substantial voluntary time and energy to support Analytical Chemistry and deserve special recognition for their contributions. In recognition of their service, this new virtual issue is dedicated to the members of both the journal’s EAB and ECB, with each selecting one of their recent Analytical Chemistry articles to highlight.

A Bright New World of Ferroelectrics: Magic of Spontaneous Polarization

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Ferroelectric materials featured with spontaneous polarization have experienced a century of vigorous development. The permanent electric dipole moment makes ferroelectric an outstanding multifunctional material for a wide range of applications. Ferroelectrics with unique coupling effects among electric, optical, mechanical, thermal, and magnetic orders, have been developed for a wide range of functional devices and triggered a new world-wide wave of ferroelectric research. This virtual issue highlights some of the key state-of-the-art findings in ferroelectrics published in ACS Applied Materials & Interfaces and ACS Applied Electronic Materials , and the editorial attempts to reflect the rapid development and provide a perspective in this field.

Peter J. Rossky Festschrift

This Virtual Special Issue honors Professor Peter J. Rossky and his contributions to the field of physical chemistry.

Computational and Experimental Advances in Biomembranes

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As an integral component of cellular architecture and signalling, cell membranes are central to cell physiology. Comprising a vastly heterogeneous mixture of proteins and lipids, cell membranes are constantly adapting their structural organization to regulate cellular processes. Malfunction at the level of lipid-protein interaction is implicated in numerous diseases, and hence, understanding cell membrane organization at the molecular level is of critical importance. The collection of articles in this Virtual Special Issue from The Journal of Physical Chemistry B provides a survey of the advances in both computational and experimental characterization of the complex processes underlying the behavior of cellular membranes.

Sensors and Industry

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In this virtual issue, ACS Sensors and Analytical Chemistry highlight 30 of these outstanding industrial co-authored papers recently published in the two journals. The breadth of the articles in this collection emphasizes the incredible research on diagnostic methods being performed in both universities and industries, and highlights the benefits of collaboration between the two. Read the Issue . ***

Machine Learning in Physical Chemistry

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Physical chemistry stands today at an exciting transition state where the integration of machine learning and data science tools into all corners of the field is poised to do nothing short of revolutionizing the discipline. These powerful techniques – when appropriately combined with domain knowledge, tools, and expertise – have led to new physical insights, better understanding, accelerated discovery, rational design, and inverse engineering that transcend traditional approaches to materials, molecular, and chemical science and engineering. This collection of nearly 150 manuscripts from The Journal of Physical Chemistry A / B / C and The Journal of Physical Chemistry Letters reflects the relevance and popularity of this topic in physical chemistry by both the depth and breadth of excellent articles in this exciting collection.

Self-Healing Materials

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This is a spotlight on applications discusses developments made over the last six years that have enabled the fabrication of increasingly high-performance spray-coated perovskite solar cells. In particular, the various approaches adopted to spray-cast perovskite films (one-step vs two-step processes) ware charted and the development of sophisticated techniques used to control thin-film crystallinity is described. Finally, remaining research challenges are discussed that, once solved, may allow the mass deployment of low-cost solar energy.

Women in Mass Spectrometry

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This virtual issue was assembled to feature talented women mass spectrometrists who publish in JASMS as the corresponding author. The articles compiled are among the most highly cited that were published in the journal in the last 5 years, regardless of gender, and are representative of the best mass spectrometry science reported in JASMS .

In Memory of Mario Molina (1943-2020)

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Mario Molina was a Mexican chemist who shared the 1995 Nobel Prize in chemistry with the late F. Sherwood Rowland of UC Irvine and Paul Crutzen of the Max Planck Institute for Chemistry in Mainz “for their work in atmospheric chemistry particularly concerning the formation and decomposition of ozone.” Molina passed away in his birth city of Mexico City at age 77 on 7 October 2020. A physical chemist at heart, Molina published about 80 papers in The Journal of Physical Chemistry . His mentees remember him by celebrating 30 of them. His indelible legacy lives on through his publications, his collaborators, the scholars that he trained, the innovations in experimental design he made, the thousands who were inspired and informed by his science communication, and the millions whose quality of life improved thanks to his work on stratospheric ozone depletion and air quality in megacities.

Women Scientists at the Forefront of Energy Research: A Virtual Issue, Part 3

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This is the third part of a series that recognizes women energy researchers who have published new advances from their laboratories in ACS Energy Letters . The inspirational stories and advice to newcomers in the field contained in this issue should provide motivation to advance the scientific research in energy conversion and storage. Through their personal reflections, these researchers discuss the successful career paths they have taken to become leaders in the scientific community.

Scalable Organic Chemistry: A Virtual Issue to highlight Organic Process Research & Development

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From small-scale use in academic research to large-scale application in industrial processes, only select chemistries make the cut to be relevant throughout the scale-up process. This virtual issue showcases a collection of innovative and industrially-relevant papers on key topics from academic and industrial chemists in Organic Process Research & Development .

Virtual Issue in Memoriam of Dr. Alan Poland (1940-2020)

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Dr. Alan Poland was a major influence on the development of modern molecular toxicology and the understanding of how chemicals cause cancer. He is most widely known for his groundbreaking work to explain the adverse effects of dioxins, chemicals and related environmental pollutants.

Deep Eutectic Solvents

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This virtual issue focuses on scientific and engineering advances related to Deep Eutectic Solvents. It includes papers that have appeared in the last two years in ACS Sustainable Chemistry & Engineering , Industrial & Engineering Chemistry Research , Journal of Chemical & Engineering Data , and Journal of Physical Chemistry B and C .

Celebrating ACS Sensors ‘ Editorial Advisory Board

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Metal-Organic Frameworks: Fundamental Study and Applications

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Exciting developments in metal-organic frameworks (MOFs) are the focus of this Virtual Issue that is jointly produced by Langmuir and ACS Applied Materials & Interfaces ( ACS AMI ). These two journals publish complementary and ground-breaking work on interfacial science. ACS AMI has a strong focus on practical applications whereas Langmuir encourages reports of both fundamental and applied nature, when rational design is a highlighted feature of the work.

Inorganic Synthesis in Uncommon Reaction Media

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Water and organic solvents have long been the most common reaction media for chemical synthesis. Nevertheless, given limits in solubility and the need for extreme temperatures sometimes, especially for inorganic substances, chemists have had a growing interest in moving to “uncommon” reaction media to improve the access to certain compounds or to permit the fundamental study of the behavior of chemicals under unique conditions. In this Virtual Issue, “Inorganic Synthesis in Uncommon Reaction Media,” Guest Editor Julia Chan and Associate Editor Stefanie Dehnen highlight recent reports from Inorganic Chemistry and additionally from Chemistry of Materials and Crystal Growth & Design that feature reactions taking place in currently used uncommon systems: molten metals (metal flux), molten salts (nonmetal flux), ionic liquids (ionothermal if carried out under elevated temperatures), supercritical solvents (solvothermal), and liquefied gases.

The Challenge of Antibacterial Drug Permeation and Current Advances

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Recent advances in the area of drug permeation feed the pipeline of antibacterial agents with new and improved activities and keep the ever-changing landscape of antibiotic resistance effectively managed by small molecule therapeutics. The articles included in this Virtual Issue broadly represent three areas of research: 1) new experimental approaches to analyze intracellular accumulation of compounds in whole cells and compound permeation across model membranes; 2) new computational models of drug permeation across the outer membrane and integrated kinetic models of drug permeation across membranes with active efflux; and 3) new antibiotic screening campaigns and exploration of synergistic drug combinations bypassing bacterial permeation barriers.

Organic Chemistry in Japan: A Strong Foundation and Honorable Tradition

Organic chemistry has a strong foundation and honorable tradition in Japan, centering in recent decades predominantly on the development of synthetic methodologies, particularly in an interdisciplinary fashion focusing on cross-coupling and C-H activation and functionalization, the total synthesis of natural products, chemical biology research, supramolecular chemistry, and applications of (opto)electronic materials—all with an eye toward fostering international collaborations. This new Organic Letters Virtual Issue features 25 selected articles form 2019-2020 to highlight these achievements.

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This virtual issue in Environmental Science & Technology ( ES&T ) marks the 50-year anniversary of the United States Environmental Protection Agency (US EPA). Recognizing this significant milestone brings an opportunity to reflect on the enormous achievements and impact this federal agency has had on the remediation and protection of the environment, reaching both domestically within the USA and globally since its official beginnings on December 2nd, 1970.

Bioconjugate Chemistry 30th Anniversary Reviews

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The breadth and impact of these 30th anniversary reviews demonstrate how the Bioconjugate Chemistry of today continues the forward-looking embrace of new science and systems while maintaining the old-fashioned virtues of scientific rigor and reproducibility.

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ACS Applied Energy Materials

ACS Applied Energy Materials

100+ Great Chemistry Research Topics

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Table of contents

  • 1 5 Tips for Writing Chemistry Research Papers
  • 2 Chemical Engineering Research Topics
  • 3 Organic Сhemistry Research Topics
  • 4 Іnorganic Сhemistry Research Topics
  • 5 Biomolecular Сhemistry Research Topics
  • 6 Analytical Chemistry Research Topics
  • 7 Computational Chemistry Research Topics
  • 8 Physical Chemistry Research Topics
  • 9 Innovative Chemistry Research Topics
  • 10 Environmental Chemistry Research Topics
  • 11 Green Chemistry Research Topics
  • 12.1 Conclusion

Do you need a topic for your chemistry research paper? Are you unsure of where to start? Don’t worry – we’re here to help. In this post, we’ll go over a series of the best chemistry research paper topics as well as Tips for Writing Chemistry Research Papers on different topics. By the time you finish reading this post, you’ll have plenty of ideas to get started on your next research project!

There are many different subfields of chemistry, so it can be tough to find interesting chemistry topics to write about. If you’re struggling to narrow down your topic, we’ll go over lists of topics in multiple fields of study.

Doing research is important to help scientists learn more about the world around us. By researching different compounds and elements, we can learn more about how they interact with one another and how they can be used to create new products or improve existing ones.

There are many different topics that you can choose to research in chemistry. Here are just a few examples:

  • The history of chemistry and how it has evolved over time
  • How different chemicals react with one another
  • How to create new compounds or improve existing ones
  • The role of chemistry in the environment
  • The health effects of different chemicals

5 Tips for Writing Chemistry Research Papers

Once you have chosen a topic for your research paper , it is important to follow some tips to ensure that your paper is well-written and accurate. Here are a few tips to get you started:

  • Start by doing some background research on your topic. This will help you understand the basics of the topic and give you a good foundation to build your paper on.
  • Make sure to cite all of the sources that you use in your paper. This will help to show where you got your information and will also help to add credibility to your work.
  • Be sure to proofread your paper before you submit it. This will ensure that there are no errors and that your paper is clear and concise.
  • Get help from a tutor or friend if you are struggling with your paper. They may be able to offer helpful advice or feedback.
  • Take your time when writing your research paper . This is not a race, and it is important to make sure that you do a good job on your research.

By following these tips, you can be sure that your chemistry research paper will be a success! So what are you waiting for? Let’s go over some of the best research paper topics out there.

Chemical Engineering Research Topics

Chemical Engineering is a branch of engineering that deals with the design and application of chemical processes. If you’re wondering how to choose a paper topic, here are some ideas to inspire you:

  • How to create new alloy compounds or improve existing ones
  • The health effects of the food industry chemicals
  • Chemical engineering and sustainable development
  • The future of chemical engineering
  • Chemical engineering and the food industry
  • Chemical engineering and the pharmaceutical industry
  • Chemical engineering and the cosmetics industry
  • Chemical engineering and the petrochemical industry
  • Biocompatible materials for drug delivery systems
  • Membrane technology in water treatment
  • Development of synthetic fibers for industrial use

These are just a few examples – there are many more possibilities out there! So get started on your research today. Who knows what you might discover!

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Organic Сhemistry Research Topics

Organic chemistry is the study of carbon-containing molecules. There are many different organic chemistry research topics that a student could choose to focus on and here are just a few examples of possible research projects in organic chemistry:

  • Investigating new methods for synthesizing chiral molecules
  • Studying the structure and reactivity of carbon nanotubes
  • Investigating metal complexes with organometallic ligands
  • Designing benzene derivatives with improved thermal stability
  • Exploring new ways to control the stereochemistry of chemical reactions
  • Studying the role of enzymes in organic synthesis
  • Investigating new strategies for combating drug resistance
  • Developing new methods for detecting explosives residues
  • Studying the photochemistry of organic molecules
  • Studying the behavior of organometallic compounds in biological systems
  • Synthetic routes for biodegradable plastics
  • Catalysis in organic synthesis
  • Development of non-toxic solvents

Іnorganic Сhemistry Research Topics

Inorganic Chemistry is the study of the chemistry of materials that do not contain carbon. Unlike other chemistry research topics, these include elements such as metals, minerals, and inorganic compounds. If you are looking for inorganic chemistry research topics on inorganic chemistry, here are some ideas to get you started:

  • How different metals react with one another
  • How to create new alloys or improve existing ones
  • The role of inorganic chemistry in the environment
  • Rare earth elements and their applications in electronics
  • Inorganic polymers in construction materials
  • Photoluminescent materials for energy conversion
  • Inorganic chemistry and sustainable development
  • The future of inorganic chemistry
  • Inorganic chemistry and the food industry
  • Inorganic chemistry and the pharmaceutical industry
  • Atomic structure progressive scale grading
  • Inorganiс Сhemistry and the cosmetics industry

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Biomolecular Сhemistry Research Topics

Biomolecular chemistry is the study of molecules that are important for life. These molecules can be found in all living things, from tiny bacteria to the largest animals. Researchers who work in this field use a variety of techniques to learn more about how these molecules function and how they interact with each other.

If you are looking for essential biomolecular chemistry research topics, here are some ideas to get you started:

  • The structure and function of DNA
  • Lipidomics and its applications in disease diagnostics
  • The structure and function of proteins
  • The role of carbohydrates in the body
  • The role of lipids in the body
  • How enzymes work
  • Protein engineering for therapeutic applications
  • The role of biochemistry in heart disease
  • Cyanides and their effect on the body
  • The role of biochemistry in cancer treatment
  • The role of biochemistry in Parkison’s disease treatment
  • The role of biochemistry in the immune system
  • Carbohydrate-based vaccines

The possibilities are endless for someone willing to dedicate some time to research.

Analytical Chemistry Research Topics

Analytical Chemistry is a type of chemistry that helps scientists figure out what something is made of. This can be done through a variety of methods, such as spectroscopy or chromatography. If you are looking for research topics, here are some ideas to get you started:

  • How food chemicals react with one another
  • Mass spectrometry
  • Microplastics detection in marine environments
  • Development of sensors for heavy metal detection in water
  • Analytical aspects of gas and liquid chromatography
  • Analytical chemistry and sustainable development
  • Atomic absorption spectroscopy methods and best practices
  • Analytical chemistry and the pharmaceutical industry in Ibuprofen consumption
  • Analytical chemistry and the cosmetics industry in UV protectors
  • High-throughput screening methods in pharmaceutical analysis
  • Dispersive X-ray analysis of damaged tissues

Analytical chemistry is considered by many a complex science and there is a lot yet to be discovered in the field.

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Computational Chemistry Research Topics

Computational chemistry is a way to use computers to help chemists understand chemical reactions. This can be done by simulating reactions or by designing new molecules. If you are looking for essential chemistry research topics in computational chemistry, here are some ideas to get you started:

  • Molecular mechanics simulation
  • Machine learning applications in predicting molecular properties
  • Reaction rates of complex chemical reactions
  • Designing new molecules: how can simulation help
  • The role of computers in the study of quantum mechanics
  • How to use computers to predict chemical reactions
  • Using computers to understand organic chemistry
  • The future of computational Chemistry in organic reactions
  • The impacts of simulation on the development of new medications
  • Combustion reaction simulation impact on engine development
  • Quantum-chemistry simulation review
  • Simulation of protein folding and misfolding in diseases
  • Development of algorithms for chemical synthesis planning
  • Applications of Metal-Organic Frameworks in water sequestration and catalysis

Computers are cutting-edge technology in chemical research and this relatively new field of study has a ton yet to be explored.

Physical Chemistry Research Topics

Physical chemistry is the study of how matter behaves. It looks at the physical and chemical properties of atoms and molecules and how they interact with each other. If you are looking for physical chemistry research topics, here are some ideas to get you started:

  • Standardization of pH scales
  • Structure of atom on a quantum scale
  • Bonding across atoms and molecules
  • The effect of temperature on chemical reactions
  • The role of light in in-body chemical reactions
  • Chemical kinetics
  • Molecular dynamics in confined spaces
  • Quantum computing for solving chemical problems
  • Studies on non-Newtonian fluids in industrial processes
  • Surface tension and its effects on mixtures
  • The role of pressure in chemical reactions
  • Rates of diffusion in gases and liquids
  • The role of entropy in chemical reactions

Here are just a few samples, but there are plenty more options! Start your research right now!

Innovative Chemistry Research Topics

Innovative chemistry is all about coming up with new ideas and ways to do things. This can be anything from creating new materials to finding new ways to make existing products. If you are looking for ground-breaking chemistry research topics, here are some ideas to get you started:

  • Amino acids side chain effects in protein folding
  • Chemistry in the production of nanomaterials
  • The role of enzymes in chemical reactions
  • Photocatalysis in 3D printing
  • Avoiding pesticides in agriculture
  • Combining chemical and biological processes
  • Gene modification in medicinal chemistry
  • The role of quantum mechanics in chemical reactions
  • Astrochemical research on extraterrestrial molecules
  • Spectroscopy signatures of pressurized organic components
  • Development of smart materials with responsive properties
  • Chemistry in space: studying chemical reactions in microgravity
  • Utilization of CO2 in chemical synthesis
  • Use of black soldier fly carcasses for bioplastic production using extracted chitin
  • Bioorthogonal chemistry for molecule synthesis inside living systems

If you need a hand, there are several sites that also offer research papers for sale and can be a great asset as you work to create your own research papers.

Whatever route you decide to take, good luck! And remember – the sky’s the limit when it comes to research! So get started today and see where your studies may take you. Who knows, you might just make a breakthrough discovery!

Environmental Chemistry Research Topics

Environmental Chemistry is the study of how chemicals interact with the environment. This can include anything from the air we breathe to the water we drink. If you are looking for environmental chemistry research topics, here are some ideas to get you started:

  • Plastic effects on ocean life
  • Urban ecology
  • The role of carbon in climate change
  • Air pollution and its effects
  • Water pollution and its effects
  • Chemicals in food and their effect on the body
  • The effect of chemicals on plant life
  • Earth temperature prediction models
  • Effects of pharmaceuticals in aquatic environments
  • Atmospheric chemistry and urban air quality
  • Bioremediation techniques for oil spill cleanup
  • Regulatory and environmental impact of Per- and Polyfluoroalkyl (PFA) substances
  • Comparison of chemical regulation impacts like PFA with historical cases such as lead in fuel

A lot of research on the environment is being conducted at the moment because the environment is in danger. There are a lot of environmental problems that need to be solved, and research is the key to solving them.

Green Chemistry Research Topics

Green chemistry is the study of how to make products and processes that are environmentally friendly. This can include anything from finding new ways to recycle materials to developing new products that are biodegradable. If you are looking for green chemistry research topics, here are some ideas to get you started:

  • Recycling and reuse of materials
  • Developing biodegradable materials
  • Improving existing recycling processes
  • Green chemistry and sustainable development
  • The future of green chemistry
  • Green chemistry and the food industry
  • Lifecycle assessment of chemical processes
  • Green chemistry and the pharmaceutical industry
  • Development of catalysts for green chemistry
  • Green chemistry and the cosmetics industry
  • Alternative energy sources for chemical synthesis

A more environmentally friendly world is something we all aspire for and a lot of research has been conducted on how we can achieve this, making this one of the most promising areas of study. The results have been varied, but there are a few key things we can do to make a difference.

Controversial Chemistry Research Topics

Controversial chemistry is all about hot-button topics that people are passionate about. This can include anything from the use of chemicals in warfare to the health effects of different chemicals. If you are looking for controversial topics to write about , here are some ideas to get you started:

  • The use of chemicals in warfare
  • Gene modification in human babies
  • Bioengineering
  • How fast food chemicals affect the human brain
  • The role of the government in regulating chemicals
  • Evolution of cigarette chemicals over time
  • Chemical effects of CBD oils
  • Ethical issues in genetic modification of organisms
  • Nuclear energy: risks and benefits
  • Use of chemicals in electronic waste recycling
  • Antidepressant chemical reactions
  • Synthetic molecule replication methods
  • Gene analysis

Controversial research papers often appear in the media before it has been peer-reviewed and published in a scientific journal. The reason for this is that the media is interested in stories that are new, exciting, and generate a lot of debate.

Chemistry is an incredibly diverse and interesting field, with many controversial topics to write about. If you are looking for a research topic, consider the examples listed in this article. With a little bit of effort, you are sure to find a topic that is both interesting and within your skillset.

In order to be a good researcher, it is important to be able to think critically and solve problems. However, innovation in chemistry research can be challenging. When thinking about how to innovate, it is important to consider both the practical and theoretical aspects of your research. Additionally, try to build on the work of others in order to create something new and unique. With a little bit of effort, you are sure to be able to find a topic that is both interesting and within your skillset.

Happy writing!

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Chemical Papers

Chemical Papers is a peer-reviewed journal focusing on basic and applied chemistry and chemical engineering research.

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Latest issue

Volume 78, Issue 7

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Research Method

Home » 300+ Chemistry Research Topics

300+ Chemistry Research Topics

Table of Contents

Chemistry Research Topics

Chemistry is a fascinating and complex field that explores the composition, properties, and behavior of matter at the molecular and atomic level. As a result, there are numerous chemistry research topics that can be explored, ranging from the development of new materials and drugs to the study of natural compounds and the environment. In this rapidly evolving field, researchers are constantly uncovering new insights and pushing the boundaries of our understanding of chemistry. Whether you are a student, a professional researcher, or simply curious about the world around you, there is always something new to discover in the field of chemistry. In this post, we will explore some of the exciting and important research topics in chemistry today.

Chemistry Research Topics

Chemistry Research Topics are as follows:

Organic Chemistry Research Topics

Organic Chemistry Research Topics are as follows:

  • Development of novel synthetic routes for the production of biologically active natural products
  • Investigation of reaction mechanisms and kinetics for organic transformations
  • Design and synthesis of new catalysts for asymmetric organic reactions
  • Synthesis and characterization of chiral compounds for pharmaceutical applications
  • Development of sustainable methods for the synthesis of organic molecules using renewable resources
  • Discovery of new reaction pathways for the conversion of biomass into high-value chemicals
  • Study of molecular recognition and host-guest interactions for drug design
  • Design and synthesis of new materials for energy storage and conversion
  • Development of efficient and selective methods for C-H functionalization reactions
  • Exploration of the reactivity of reactive intermediates such as radicals and carbenes
  • Study of supramolecular chemistry and self-assembly of organic molecules
  • Development of new methods for the synthesis of heterocyclic compounds
  • Investigation of the biological activities and mechanisms of action of natural products
  • Synthesis of polymeric materials with controlled architecture and functionality
  • Development of new synthetic methodologies for the preparation of bioconjugates
  • Investigation of the mechanisms of enzyme catalysis and the design of enzyme inhibitors
  • Synthesis and characterization of novel fluorescent probes for biological imaging
  • Development of new synthetic strategies for the preparation of carbohydrates and glycoconjugates
  • Study of the properties and reactivity of carbon nanomaterials
  • Design and synthesis of novel drugs for the treatment of diseases such as cancer, diabetes, and Alzheimer’s disease.

Inorganic Chemistry Research Topics

Inorganic Chemistry Research Topics are as follows:

  • Synthesis and characterization of new metal-organic frameworks (MOFs) for gas storage and separation applications
  • Development of new catalysts for sustainable chemical synthesis reactions
  • Investigation of the electronic and magnetic properties of transition metal complexes for spintronics applications
  • Synthesis and characterization of novel nanomaterials for energy storage applications
  • Development of new ligands for metal coordination complexes with potential medical applications
  • Investigation of the mechanism of metal-catalyzed reactions using advanced spectroscopic techniques
  • Synthesis and characterization of new inorganic materials for photocatalytic water splitting
  • Development of new materials for electrochemical carbon dioxide reduction reactions
  • Investigation of the properties of transition metal oxides for energy storage and conversion applications
  • Synthesis and characterization of new metal chalcogenides for optoelectronic applications
  • Development of new methods for the preparation of inorganic nanoparticles with controlled size and shape
  • Investigation of the reactivity and catalytic properties of metal clusters
  • Synthesis and characterization of new metal-organic polyhedra (MOPs) for gas storage and separation applications
  • Development of new methods for the synthesis of metal nanoparticles using environmentally friendly reducing agents
  • Investigation of the properties of metal-organic frameworks for gas sensing applications
  • Synthesis and characterization of new coordination polymers with potential magnetic and electronic properties
  • Development of new materials for electrocatalytic water oxidation reactions
  • Investigation of the properties of metal-organic frameworks for carbon capture and storage applications
  • Synthesis and characterization of new metal-containing polymers with potential applications in electronics and energy storage
  • Development of new methods for the synthesis of metal-organic frameworks using green solvents and renewable resources.

Physical Chemistry Research Topics

Physical Chemistry Research Topics are as follows:

  • Investigation of the properties and interactions of ionic liquids in aqueous and non-aqueous solutions.
  • Development of advanced analytical techniques for the study of protein structure and dynamics.
  • Investigation of the thermodynamic properties of supercritical fluids for use in industrial applications.
  • Development of novel nanomaterials for energy storage applications.
  • Studies of the surface chemistry of catalysts for the optimization of their performance in chemical reactions.
  • Development of new methods for the synthesis of complex organic molecules with improved yields and selectivity.
  • Investigation of the molecular mechanisms involved in the catalysis of biochemical reactions.
  • Development of new strategies for the controlled release of drugs and other bioactive molecules.
  • Studies of the interaction of nanoparticles with biological systems for biomedical applications.
  • Investigation of the thermodynamic properties of materials under extreme conditions of temperature and pressure.
  • Development of new methods for the characterization of materials at the nanoscale.
  • Investigation of the electronic and magnetic properties of materials for use in spintronics.
  • Development of new materials for energy conversion and storage.
  • Studies of the kinetics and thermodynamics of adsorption processes on surfaces.
  • Investigation of the transport properties of ionic liquids for use in energy storage and conversion devices.
  • Development of new materials for the capture and sequestration of greenhouse gases.
  • Studies of the structure and properties of biomolecules for use in drug design and development.
  • Investigation of the dynamics of chemical reactions in solution using time-resolved spectroscopic techniques.
  • Development of new approaches for the synthesis of metallic and semiconductor nanoparticles with controlled size and shape.
  • Studies of the structure and properties of materials for use in electrochemical energy storage devices.

Analytical Chemistry Research Topics

Analytical Chemistry Research Topics are as follows:

  • Development and optimization of analytical techniques for the quantification of trace elements in food and environmental samples.
  • Design and synthesis of novel analytical probes for the detection of biomolecules in complex matrices.
  • Investigation of the fundamental mechanisms involved in the separation and detection of complex mixtures using chromatographic techniques.
  • Development of sensors and biosensors for the detection of chemical and biological species in real-time.
  • Investigation of the chemical and structural properties of nanomaterials and their applications in analytical chemistry.
  • Development and validation of analytical methods for the quantification of contaminants and pollutants in water, air, and soil.
  • Investigation of the molecular mechanisms underlying drug metabolism and toxicity using mass spectrometry.
  • Development of analytical tools for the identification and quantification of drugs of abuse in biological matrices.
  • Investigation of the chemical composition and properties of natural products and their applications in medicine and food science.
  • Development of advanced analytical techniques for the characterization of proteins and peptides.
  • Investigation of the chemistry and mechanism of action of antioxidants in foods and their impact on human health.
  • Development of analytical methods for the detection and quantification of microorganisms in food and environmental samples.
  • Investigation of the molecular mechanisms involved in the biosynthesis and degradation of important biomolecules such as proteins, carbohydrates, and lipids.
  • Development of analytical methods for the detection and quantification of environmental toxins and their impact on human health.
  • Investigation of the structure and properties of biological membranes and their role in drug delivery and disease.
  • Development of analytical techniques for the characterization of complex mixtures such as petroleum and crude oil.
  • Investigation of the chemistry and mechanism of action of natural and synthetic dyes.
  • Development of analytical techniques for the detection and quantification of pharmaceuticals and personal care products in water and wastewater.
  • Investigation of the chemical composition and properties of biopolymers and their applications in biomedicine and biomaterials.
  • Development of analytical methods for the identification and quantification of essential nutrients and vitamins in food and dietary supplements.

Biochemistry Research Topics

Biochemistry Research Topics are as follows:

  • The role of enzymes in metabolic pathways
  • The biochemistry of DNA replication and repair
  • Protein folding and misfolding diseases
  • Lipid metabolism and the pathogenesis of atherosclerosis
  • The role of vitamins and minerals in human metabolism
  • Biochemistry of cancer and the development of targeted therapies
  • The biochemistry of signal transduction pathways and their regulation
  • The mechanisms of antibiotic resistance in bacteria
  • The biochemistry of neurotransmitters and their roles in behavior and disease
  • The role of oxidative stress in aging and age-related diseases
  • The biochemistry of microbial fermentation and its applications in industry
  • The biochemistry of the immune system and its response to pathogens
  • The biochemistry of plant metabolism and its regulation
  • The molecular basis of genetic diseases and gene therapy
  • The biochemistry of membrane transport and its role in cell function
  • The biochemistry of muscle contraction and its regulation
  • The role of lipids in membrane structure and function
  • The biochemistry of photosynthesis and its regulation
  • The biochemistry of RNA splicing and alternative splicing events
  • The biochemistry of epigenetics and its regulation in gene expression.

Environmental Chemistry Research Topics

Environmental Chemistry Research Topics are as follows:

  • Investigating the effects of microplastics on aquatic ecosystems and their potential impact on human health.
  • Examining the impact of climate change on soil quality and nutrient availability in agricultural systems.
  • Developing methods to improve the removal of heavy metals from contaminated soils and waterways.
  • Assessing the effectiveness of natural and synthetic antioxidants in mitigating the effects of air pollution on human health.
  • Investigating the potential for using algae and other microorganisms to sequester carbon dioxide from the atmosphere.
  • Studying the role of biodegradable plastics in reducing plastic waste and their impact on the environment.
  • Examining the impact of pesticides and other agricultural chemicals on water quality and the health of aquatic organisms.
  • Investigating the effects of ocean acidification on marine organisms and ecosystems.
  • Developing new materials and technologies to reduce carbon emissions from industrial processes.
  • Evaluating the effectiveness of phytoremediation in cleaning up contaminated soils and waterways.
  • Studying the impact of microplastics on terrestrial ecosystems and their potential to enter the food chain.
  • Developing sustainable methods for managing and recycling electronic waste.
  • Investigating the role of natural processes, such as weathering and erosion, in regulating atmospheric carbon dioxide levels.
  • Assessing the impact of urbanization on air quality and developing strategies to mitigate pollution in cities.
  • Examining the effects of climate change on the distribution and abundance of species in different ecosystems.
  • Investigating the impact of ocean currents on the distribution of pollutants and other environmental contaminants.
  • Developing new materials and technologies for renewable energy generation and storage.
  • Studying the effects of deforestation on soil quality, water availability, and biodiversity.
  • Assessing the potential for using waste materials, such as agricultural residues and municipal solid waste, as sources of renewable energy.
  • Investigating the role of natural and synthetic chemicals in regulating ecosystem functions, such as nutrient cycling and carbon sequestration.

Polymer Chemistry Research Topics

Polymer Chemistry Research Topics are as follows:

  • Development of new monomers for high-performance polymers
  • Synthesis and characterization of biodegradable polymers for sustainable packaging
  • Design of stimuli-responsive polymers for drug delivery applications
  • Investigation of the properties and applications of conductive polymers
  • Development of new catalysts for controlled/living polymerization
  • Synthesis of polymers with tailored mechanical properties
  • Characterization of the structure-property relationship in polymer nanocomposites
  • Study of the impact of polymer architecture on material properties
  • Design and synthesis of new polymeric materials for energy storage
  • Development of high-throughput methods for polymer synthesis and characterization
  • Exploration of new strategies for polymer recycling and upcycling
  • Synthesis and characterization of responsive polymer networks for smart textiles
  • Design of advanced polymer coatings with self-healing properties
  • Investigation of the impact of processing conditions on the morphology and properties of polymer materials
  • Study of the interactions between polymers and biological systems
  • Development of biocompatible polymers for tissue engineering applications
  • Synthesis and characterization of block copolymers for advanced membrane applications
  • Exploration of the potential of polymer-based sensors and actuators
  • Design of novel polymer electrolytes for advanced batteries and fuel cells
  • Study of the behavior of polymers under extreme conditions, such as high pressure or temperature.

Materials Chemistry Research Topics

Materials Chemistry Research Topics are as follows:

  • Development of new advanced materials for energy storage and conversion
  • Synthesis and characterization of nanomaterials for environmental remediation
  • Design and fabrication of stimuli-responsive materials for drug delivery
  • Investigation of electrocatalytic materials for fuel cells and electrolysis
  • Fabrication of flexible and stretchable electronic materials for wearable devices
  • Development of novel materials for high-performance electronic devices
  • Exploration of organic-inorganic hybrid materials for optoelectronic applications
  • Study of corrosion-resistant coatings for metallic materials
  • Investigation of biomaterials for tissue engineering and regenerative medicine
  • Synthesis and characterization of metal-organic frameworks for gas storage and separation
  • Design and fabrication of new materials for water purification
  • Investigation of carbon-based materials for supercapacitors and batteries
  • Synthesis and characterization of self-healing materials for structural applications
  • Development of new materials for catalysis and chemical reactions
  • Exploration of magnetic materials for spintronic devices
  • Investigation of thermoelectric materials for energy conversion
  • Study of 2D materials for electronic and optoelectronic applications
  • Development of sustainable and eco-friendly materials for packaging
  • Fabrication of advanced materials for sensors and actuators
  • Investigation of materials for high-temperature applications such as aerospace and nuclear industries.

Nuclear Chemistry Research Topics

Nuclear Chemistry Research Topics are as follows:

  • Nuclear fission and fusion reactions
  • Nuclear power plant safety and radiation protection
  • Radioactive waste management and disposal
  • Nuclear fuel cycle and waste reprocessing
  • Nuclear energy and its impact on climate change
  • Radiation therapy for cancer treatment
  • Radiopharmaceuticals for medical imaging
  • Nuclear medicine and its role in diagnostics
  • Nuclear forensics and nuclear security
  • Isotopic analysis in environmental monitoring and pollution control
  • Nuclear magnetic resonance (NMR) spectroscopy
  • Nuclear magnetic resonance imaging (MRI)
  • Radiation damage in materials and radiation effects on electronic devices
  • Nuclear data evaluation and validation
  • Nuclear reactors design and optimization
  • Nuclear fuel performance and irradiation behavior
  • Nuclear energy systems integration and optimization
  • Neutron and gamma-ray detection and measurement techniques
  • Nuclear astrophysics and cosmology
  • Nuclear weapons proliferation and disarmament.

Medicinal Chemistry Research Topics

Medicinal Chemistry Research Topics are as follows:

  • Drug discovery and development
  • Design and synthesis of novel drugs
  • Medicinal chemistry of natural products
  • Structure-activity relationships (SAR) of drugs
  • Rational drug design using computational methods
  • Target identification and validation
  • Drug metabolism and pharmacokinetics (DMPK)
  • Drug delivery systems
  • Development of new antibiotics
  • Design of drugs for the treatment of cancer
  • Development of drugs for the treatment of neurological disorders
  • Medicinal chemistry of peptides and proteins
  • Development of drugs for the treatment of infectious diseases
  • Discovery of new antiviral agents
  • Design of drugs for the treatment of cardiovascular diseases
  • Medicinal chemistry of enzyme inhibitors
  • Development of drugs for the treatment of inflammatory diseases
  • Design of drugs for the treatment of metabolic disorders
  • Medicinal chemistry of anti-cancer agents
  • Development of drugs for the treatment of rare diseases.

Food Chemistry Research Topics

Food Chemistry Research Topics are as follows:

  • Investigating the effect of cooking methods on the nutritional value of food.
  • Analyzing the role of antioxidants in preventing food spoilage and degradation.
  • Examining the effect of food processing techniques on the nutritional value of fruits and vegetables.
  • Studying the chemistry of food additives and their impact on human health.
  • Evaluating the role of enzymes in food digestion and processing.
  • Investigating the chemical properties and functional uses of food proteins.
  • Analyzing the effect of food packaging materials on the quality and safety of food products.
  • Examining the chemistry of food flavorings and the impact of flavor on consumer acceptance.
  • Studying the role of carbohydrates in food texture and structure.
  • Investigating the chemistry of food lipids and their impact on human health.
  • Analyzing the chemical properties and functional uses of food gums and emulsifiers.
  • Examining the effect of processing on the flavor and aroma of food products.
  • Studying the chemistry of food preservatives and their impact on food safety.
  • Investigating the chemical properties and functional uses of food fibers.
  • Analyzing the effect of food processing on the bioavailability of nutrients.
  • Examining the chemistry of food colorants and their impact on consumer acceptance.
  • Studying the role of vitamins and minerals in food and their impact on human health.
  • Investigating the chemical properties and functional uses of food hydrocolloids.
  • Analyzing the effect of food processing on the allergenicity of food products.
  • Examining the chemistry of food sweeteners and their impact on human health.

Industrial Chemistry Research Topics

Industrial Chemistry Research Topics are as follows:

  • Development of catalysts for selective hydrogenation reactions in the petrochemical industry.
  • Green chemistry approaches for the synthesis of biodegradable polymers from renewable sources.
  • Optimization of solvent extraction processes for the separation of rare earth elements from ores.
  • Development of novel materials for energy storage applications, such as lithium-ion batteries.
  • Production of biofuels from non-food sources, such as algae or waste biomass.
  • Application of computational chemistry to optimize the design of new catalysts and materials.
  • Design and optimization of continuous flow processes for large-scale chemical production.
  • Development of new synthetic routes for the production of pharmaceutical intermediates.
  • Investigation of the environmental impact of industrial processes and development of sustainable alternatives.
  • Development of innovative water treatment technologies for industrial wastewater.
  • Synthesis of functionalized nanoparticles for use in drug delivery and other biomedical applications.
  • Optimization of processes for the production of high-performance polymers, such as polyamides or polyesters.
  • Design and optimization of process control strategies for efficient and safe chemical production.
  • Development of new methods for the detection and removal of heavy metal ions from industrial effluents.
  • Investigation of the behavior of surfactants in complex mixtures, such as crude oil or food products.
  • Development of new materials for catalytic oxidation reactions, such as the removal of volatile organic compounds from air.
  • Investigation of the properties and behavior of materials under extreme conditions, such as high pressure or high temperature.
  • Development of new processes for the production of chemicals from renewable resources, such as bio-based building blocks.
  • Study of the kinetics and mechanism of chemical reactions in complex systems, such as multi-phase reactors.
  • Optimization of the production of fine chemicals, such as flavors and fragrances, using biocatalytic processes.

Computational Chemistry Research Topics

Computational Chemistry Research Topics are as follows:

  • Development and application of machine learning algorithms for predicting chemical reactions and properties.
  • Investigation of the role of solvents in chemical reactions using molecular dynamics simulations.
  • Modeling and simulation of protein-ligand interactions to aid drug design.
  • Study of the electronic structure and reactivity of catalysts for sustainable energy production.
  • Analysis of the thermodynamics and kinetics of complex chemical reactions using quantum chemistry methods.
  • Exploration of the mechanism and kinetics of enzyme-catalyzed reactions using molecular dynamics simulations.
  • Investigation of the properties and behavior of nanoparticles using computational modeling.
  • Development of computational tools for the prediction of chemical toxicity and environmental impact.
  • Study of the electronic properties of graphene and other 2D materials for applications in electronics and energy storage.
  • Investigation of the mechanisms of protein folding and aggregation using molecular dynamics simulations.
  • Development and optimization of computational methods for calculating thermodynamic properties of liquids and solids.
  • Study of the properties of supercritical fluids for applications in separation and extraction processes.
  • Development of new methods for the calculation of electron transfer rates in complex systems.
  • Investigation of the electronic and mechanical properties of carbon nanotubes for applications in nanoelectronics and nanocomposites.
  • Development of new approaches for modeling the interaction of biomolecules with biological membranes.
  • Study of the mechanisms of charge transfer in molecular and hybrid solar cells.
  • Analysis of the structural and mechanical properties of materials under extreme conditions using molecular dynamics simulations.
  • Development of new approaches for the calculation of free energy differences in complex systems.
  • Investigation of the reaction mechanisms of metalloenzymes using quantum mechanics/molecular mechanics (QM/MM) methods.
  • Study of the properties of ionic liquids for applications in catalysis and energy storage.

Theoretical Chemistry Research Topics

Theoretical Chemistry Research Topics are as follows:

  • Quantum Chemical Studies of Excited State Processes in Organic Molecules
  • Theoretical Investigation of Structure and Reactivity of Metal-Organic Frameworks
  • Computational Modeling of Reaction Mechanisms and Kinetics in Enzyme Catalysis
  • Theoretical Investigation of Non-Covalent Interactions in Supramolecular Chemistry
  • Quantum Chemical Studies of Photochemical Processes in Organic Molecules
  • Theoretical Analysis of Charge Transport in Organic and Inorganic Materials
  • Computational Modeling of Protein Folding and Dynamics
  • Quantum Chemical Investigations of Electron Transfer Processes in Complex Systems
  • Theoretical Studies of Surface Chemistry and Catalysis
  • Computational Design of Novel Materials for Energy Storage Applications
  • Theoretical Analysis of Chemical Bonding and Molecular Orbital Theory
  • Quantum Chemical Investigations of Magnetic Properties of Complex Systems
  • Computational Modeling of Biological Membranes and Transport Processes
  • Theoretical Studies of Nonlinear Optical Properties of Molecules and Materials
  • Quantum Chemical Studies of Spectroscopic Properties of Molecules
  • Theoretical Investigations of Reaction Mechanisms in Organometallic Chemistry
  • Computational Modeling of Heterogeneous Catalysis
  • Quantum Chemical Studies of Excited State Dynamics in Photosynthesis
  • Theoretical Analysis of Chemical Reaction Networks
  • Computational Design of Nanomaterials for Biomedical Applications

Astrochemistry Research Topics

Astrochemistry Research Topics are as follows:

  • Investigating the chemical composition of protoplanetary disks and its implications for planet formation
  • Examining the role of magnetic fields in the formation of complex organic molecules in space
  • Studying the effects of interstellar radiation on the chemical evolution of molecular clouds
  • Exploring the chemistry of comets and asteroids to better understand the early solar system
  • Investigating the origin and evolution of interstellar dust and its relationship to organic molecules
  • Examining the formation and destruction of interstellar molecules in shocked gas
  • Studying the chemical processes that occur in the atmospheres of planets and moons in our solar system
  • Exploring the possibility of life on other planets through astrobiology and astrochemistry
  • Investigating the chemistry of planetary nebulae and their role in the evolution of stars
  • Studying the chemical properties of exoplanets and their potential habitability
  • Examining the chemical reactions that occur in the interstellar medium
  • Investigating the chemical composition of supernova remnants and their impact on the evolution of galaxies
  • Studying the chemical composition of interstellar grains and their role in the formation of stars and planets
  • Exploring the chemistry of astrocytes and their role in the evolution of galaxies
  • Investigating the formation of interstellar ice and its implications for the origin of life
  • Examining the chemistry of molecular clouds and its relationship to star formation
  • Studying the chemical composition of the interstellar medium in different galaxies and how it varies
  • Investigating the role of cosmic rays in the formation of complex organic molecules in space
  • Exploring the chemical properties of interstellar filaments and their relationship to star formation
  • Studying the chemistry of protostars and the role of turbulence in the formation of stars.

Geochemistry Research Topics

Geochemistry Research Topics are as follows:

  • Understanding the role of mineralogical and geochemical factors on metal mobility in contaminated soils
  • Investigating the sources and fate of dissolved organic matter in aquatic systems
  • Exploring the geochemical signatures of ancient sedimentary rocks to reconstruct Earth’s past atmospheric conditions
  • Studying the impacts of land-use change on soil organic matter content and quality
  • Investigating the impact of acid mine drainage on water quality and ecosystem health
  • Examining the processes controlling the behavior and fate of emerging contaminants in the environment
  • Characterizing the organic matter composition of shale gas formations to better understand hydrocarbon storage and migration
  • Evaluating the potential for carbon capture and storage in geologic formations
  • Investigating the geochemical processes controlling the formation and evolution of ore deposits
  • Studying the geochemistry of geothermal systems to better understand energy production potential and environmental impacts
  • Exploring the impacts of climate change on the biogeochemistry of terrestrial ecosystems
  • Investigating the geochemical cycling of nutrients in coastal marine environments
  • Characterizing the isotopic composition of minerals and fluids to understand Earth’s evolution
  • Developing new analytical techniques to better understand the chemistry of natural waters
  • Studying the impact of anthropogenic activities on the geochemistry of urban soils
  • Investigating the role of microbial processes in geochemical cycling of elements in soils and sediments
  • Examining the impact of wildfires on soil and water chemistry
  • Characterizing the geochemistry of mineral dust and its impact on climate and biogeochemical cycles
  • Investigating the geochemical factors controlling the release and transport of contaminants from mine tailings
  • Exploring the biogeochemistry of wetlands and their role in carbon sequestration and nutrient cycling.

Electrochemistry Research Topics

Electrochemistry Research Topics are as follows:

  • Development of high-performance electrocatalysts for efficient electrochemical conversion of CO2 to fuels and chemicals
  • Investigation of electrode-electrolyte interfaces in lithium-ion batteries for enhanced battery performance and durability
  • Design and synthesis of novel electrolytes for high-energy-density and stable lithium-sulfur batteries
  • Development of advanced electrochemical sensors for the detection of trace-levels of analytes in biological and environmental samples
  • Analysis of the electrochemical behavior of new materials and their electrocatalytic properties in fuel cells
  • Study of the kinetics of electrochemical reactions and their effect on the efficiency and selectivity of electrochemical processes
  • Development of novel strategies for the electrochemical synthesis of value-added chemicals from biomass and waste materials
  • Analysis of the electrochemical properties of metal-organic frameworks (MOFs) for energy storage and conversion applications
  • Investigation of the electrochemical degradation mechanisms of polymer electrolyte membranes in fuel cells
  • Study of the electrochemical properties of 2D materials and their applications in energy storage and conversion devices
  • Development of efficient electrochemical systems for desalination and water treatment applications
  • Investigation of the electrochemical properties of metal-oxide nanoparticles for energy storage and conversion applications
  • Analysis of the electrochemical behavior of redox-active organic molecules and their application in energy storage and conversion devices
  • Study of the electrochemical behavior of metal-organic frameworks (MOFs) for the catalytic conversion of CO2 to value-added chemicals
  • Development of novel electrode materials for electrochemical capacitors with high energy density and fast charge/discharge rates
  • Investigation of the electrochemical properties of perovskite materials for energy storage and conversion applications
  • Study of the electrochemical behavior of enzymes and their application in bioelectrochemical systems
  • Development of advanced electrochemical techniques for the characterization of interfacial processes in electrochemical systems
  • Analysis of the electrochemical behavior of nanocarbons and their application in electrochemical energy storage devices
  • Investigation of the electrochemical properties of ionic liquids for energy storage and conversion applications.

Surface Chemistry Research Topics

Surface Chemistry Research Topics are as follows:

  • Surface modification of nanoparticles for enhanced catalytic activity
  • Investigating the effect of surface roughness on the wetting behavior of materials
  • Development of new materials for solar cell applications through surface chemistry techniques
  • Surface chemistry of graphene and its applications in electronic devices
  • Surface functionalization of biomaterials for biomedical applications
  • Characterization of surface defects and their effect on material properties
  • Surface modification of carbon nanotubes for energy storage applications
  • Developing surface coatings for corrosion protection of metals
  • Synthesis of self-assembled monolayers on surfaces for sensor applications
  • Surface chemistry of metal-organic frameworks for gas storage and separation
  • Investigating the role of surface charge in protein adsorption
  • Developing surfaces with superhydrophobic or superoleophobic properties for self-cleaning applications
  • Surface functionalization of nanoparticles for drug delivery applications
  • Surface chemistry of semiconductors and its effect on photovoltaic properties
  • Development of surface-enhanced Raman scattering (SERS) substrates for trace analyte detection
  • Surface functionalization of graphene oxide for water purification applications
  • Investigating the role of surface tension in emulsion formation and stabilization
  • Surface modification of membranes for water desalination and purification
  • Synthesis and characterization of metal nanoparticles for catalytic applications
  • Development of surfaces with controlled wettability for microfluidic applications.

Atmospheric Chemistry Research Topics

Atmospheric Chemistry Research Topics are as follows:

  • The impact of wildfires on atmospheric chemistry
  • The role of aerosols in atmospheric chemistry
  • The chemistry and physics of ozone depletion in the stratosphere
  • The chemistry and dynamics of the upper atmosphere
  • The impact of anthropogenic emissions on atmospheric chemistry
  • The role of clouds in atmospheric chemistry
  • The chemistry of atmospheric particulate matter
  • The impact of nitrogen oxides on atmospheric chemistry and air quality
  • The effects of climate change on atmospheric chemistry
  • The impact of atmospheric chemistry on climate change
  • The chemistry and physics of atmospheric mercury cycling
  • The impact of volcanic eruptions on atmospheric chemistry
  • The chemistry and physics of acid rain formation and effects
  • The role of halogen chemistry in the atmosphere
  • The chemistry of atmospheric radicals and their impact on air quality and health
  • The impact of urbanization on atmospheric chemistry
  • The chemistry and physics of stratospheric polar vortex dynamics
  • The role of natural sources (e.g. ocean, plants) in atmospheric chemistry
  • The impact of atmospheric chemistry on the biosphere
  • The chemistry and dynamics of the ozone hole over Antarctica.

Photochemistry Research Topics

Photochemistry Research Topics are as follows:

  • Investigating the mechanisms of photoinduced electron transfer reactions in organic photovoltaic materials.
  • Developing novel photoredox catalysts for photochemical reactions.
  • Understanding the effects of light on DNA and RNA stability and replication.
  • Studying the photochemistry of atmospheric pollutants and their impact on air quality.
  • Designing new photoresponsive materials for advanced photonic and electronic devices.
  • Exploring the photochemistry of metalloporphyrins for potential applications in catalysis.
  • Investigating the photochemistry of transition metal complexes and their use as photodynamic therapy agents.
  • Developing new photocatalytic systems for sustainable energy production.
  • Studying the photochemistry of natural products and their potential pharmaceutical applications.
  • Investigating the role of light in the formation and degradation of environmental contaminants.
  • Designing new photochromic materials for smart windows and displays.
  • Exploring the photochemistry of carbon nanomaterials for energy storage and conversion.
  • Developing new light-driven molecular machines for nanotechnology applications.
  • Investigating the photochemistry of organic dyes for potential applications in dye-sensitized solar cells.
  • Studying the effects of light on the behavior of biological macromolecules.
  • Designing new photoresponsive hydrogels for drug delivery applications.
  • Exploring the photochemistry of semiconductor nanoparticles for potential applications in quantum computing.
  • Investigating the mechanisms of photochemical reactions in ionic liquids.
  • Developing new photonic sensors for chemical and biological detection.
  • Studying the photochemistry of transition metal complexes for potential applications in water splitting and hydrogen production.

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Do you find identifying suitable chemistry research topics difficult? You are not alone! Many students consider it challenging and time-consuming to choose an interesting chemistry topic for a research paper. In this blog post, we will discuss various research topics in chemistry to help simplify your research process. Continue reading to familiarize yourself with ideas from different fields and academic levels. Apart from defining research topics and discussing how to select one, we have provided examples to help kick-start your research project or assignments. Got a deadline approaching fast? Entrust your chemistry research paper to professional writers. Our academic service proceeds all ‘ write my paper for me ’ inquiries quickly and efficiently. Get your paper written now by an expert!

What Are Chemistry Research Topics?

Chemistry is a field of science that covers the structure, composition, and properties of elements and compounds. As a student taking this subject, you will encounter multiple experiments, chemical reactions, and analytical study methods. This branch of science can be subdivided into multiple areas, including organic, inorganic, biochemistry, physical, analytical, and nuclear science, among others. Chemistry research paper topics are talking points related to the branches of science outlined above. To ensure that all learning objectives are met, instructors may require students to work on various topics in chemistry. You would be expected to source your chemistry research topics ideas from all possible branches. In one instance, your topic could be associated with analytical science, in another - with practical discussions, which is an entirely different thing despite both areas being categorized as chemistry subfields.

Characteristics of Good Chemistry Research Topics

Selecting a good research topic for chemistry plays a vital role in determining the probability of success when writing your paper. It is, therefore, important to know the characteristics of good chemistry topics for a research paper. Although you can derive discussions from many sub-areas, these research topic ideas share many common characteristics. A great research topic should be:

  • Precise, meaningful, clear, and straightforward
  • Analytical and researchable using logical methodologies
  • Of theoretical or practical significance
  • Supported by numerous academic evidence and sources.

How to Choose a Chemistry Research Topic?

Chemistry is a broad subject with multiple research areas. If you are not keen enough, you may easily get lost in its variety and fail to select a congenial title. So, how do you deal with this issue? In a nutshell, the process comes down to two aspects – your passion and competence. Below are step-by-step guidelines that you can follow to determine interesting topics about chemistry:

  • Pick chemistry research topics with your knowledge capabilities in mind. Do not choose a topic that is beyond your academic level.
  • Choose something that is interesting to you. If you are fascinated with the selected topic, you will find responding to the research questions to be much simpler.
  • Select a research title that is convenient to work on due to the sufficient amount and availability of existing evidence and references.
  • Ensure that the chosen chemistry topics for research paper are within the subfield you are majoring in and that it meets your instructor’s requirements.

Once you select the most appropriate title, see how to write a research paper like an expert.

Chemistry Research Paper Topics List

There are many research topics for chemistry to choose from. In this section, we have compiled examples of the best topics from various sub-areas. Below is a list of chemistry research topics for papers:

  • Latest developments in DNA technology.
  • Negative effects of using pesticides in food production.
  • Importance and potential drawbacks of using fertilizer in commercial agriculture.
  • Acids and bases: composition, properties, and applications.
  • Industrial chemicals and environmental pollution.
  • Dangers and side effects of using ibuprofen.
  • Acid-base neutralization process.
  • Air pollution implication on global warming and climate change.
  • Ageing and the brain.
  • Catalytic reaction mechanisms.

The chemistry research topics list above is created by drawing ideas from different sub-areas, thus covering a significant part of scholars’ inquiries.

Interesting Topics in Chemistry

In some instances, one may select a research topic because it is just fascinating. There are interesting chemistry topics that can explain intriguing phenomena in your day-to-day life. Alternatively, you can also opt for something related to essential issues in the current society. Here are sample chemistry interesting topics you can research into:

  • Composition and effects of e-cigarettes.
  • Food dye composition.
  • Measuring electrical conductivity in a salt solution.
  • How to change a penny’s color to gold.
  • The scientific explanation of foam formation.
  • Silicon usage in cosmetic surgery.
  • Evidence and application of surface tension in day-to-day life.
  • Examining pesticide residue in farm products from different grocery stores.
  • How does molecule composition affect the physical appearance of things?
  • Sodium metal reaction on water surfaces.
  • How to separate dissolved sugar from water.
  • How to clean up oil spills at sea.
  • Rust formation on metal surfaces.
  • How to chemically remove rust from stainless steel.
  • The science behind turning boiling water into “snow” in a cold winter.

Easy Chemistry Research Topics

The science studied in high schools is way simpler compared to postgraduate one. You can find easy chemistry topics to research if you focus on certain academic levels and sub-areas. For example, physical chemistry has easy chemistry topics to do research paper on. On the other side, inorganic or analytical sub-areas tend to offer scientific research research topics that are more technical. The list below outlines easy topic examples you can pick from:

  • Determining the percentage composition of oxygen in the air.
  • Patterns in the periodic table.
  • Atomic theory: primary principles and applications.
  • Chemical and physical properties of starch.
  • Determining the pH level of various liquids.
  • Properties of acids and bases.
  • Why is glass the preferred material in laboratories?
  • Balancing chemical equations.
  • Analyzing different chemical bonds.
  • Alkali metals and their properties.
  • General characteristics of metals.
  • Noble gasses: properties and reaction characteristics.
  • Water purification methods.
  • The periodic table: its historical background.
  • Alkaline earth metals: properties and reactivity.

Innovative Research Topics in Chemistry

Innovative chemistry topics for research paper relate to new ideas and ways to go about things. Using these ground-breaking topics related to chemistry, you can discuss new materials or methodologies. If you are interested in innovative research topics, here are some examples you can borrow from:

  • Gene modification in medical chemistry .
  • Improved cancer treatment using bacteria-based biohybrid microrobots.
  • New methods used to detect explosive residues.
  • Studying the molecular makeup of particles in space.
  • Substitute for pesticides in farming.
  • Nanophotonics in aeronautics.
  • Nanomaterials production process and techniques.
  • Clean energy alternatives for fossil fuels.
  • Photocatalysis usage in 3D printing technology.
  • Biodegradable polymers as alternatives for plastics.
  • Silicon dioxide usage in solar cells.
  • Chemical reactions in lithium-ion batteries.
  • Self-healing concrete: basic principles.
  • New materials for lightweight planes and vehicles.
  • Polymer analysis in a restricted environment.

Cool Chemistry Research Topics

Sometimes, our title selection might be guided by how cool and fun the study results will be. If you are looking for cool chemistry topics to research on, you are in the right place. We have compiled some cool chemistry topics for you to choose from.

  • How World War II influenced computational chemistry.
  • How do chemicals in our brains create different moods?
  • Composition and properties of laughing gas.
  • European alchemy: historical background and its impact on modern science.
  • Developing a film at home: chemicals required and process.
  • Why lemon juice stops apples from browning.
  • Different flame colors and their scientific explanation.
  • Using a potato to light a bulb.
  • Principles of chromatography.
  • Utilizing cloud seeding in alleviating drought conditions.
  • Finding iron in a mixture of metals.
  • Gas chromatography: how it works and its applications.
  • Application of vibrational spectroscopy.
  • Surface tension and the dish soap experiment.
  • How to make a homemade water filter.

Have you spotted any ideas but can’t get the research process started? Contact our professional writing service where you can pay for research paper and be sure that you will get outstanding results within your deadline. 

Intriguing Chemistry Topics for Research

There are many chemistry topics to write about. However, not all topics are intriguing (and frankly, most are the other way around). Below are topic examples that can instantly draw readers’ attention:

  • Non-existing chemical compounds.
  • Molecular structure of artificial honey as compared to natural honey.
  • Stem cell studies: ethical implications.
  • Principles of polymerase chain reaction and DNA replication.
  • Organic chemistry applications in our daily living.
  • Chemicals as weapons of mass destruction.
  • How does adding sugar to a soft drink affect its density?
  • Synthetic molecules in the pharmaceutical industry .
  • Aerosol formation and its application in body spray manufacture.
  • Analyzing the gasoline production process.
  • Benzene molecular structure and its use in the cosmetic industry.
  • Why are 96,000,000 black balls dumped into the LA reservoir?
  • Water recycling methods.
  • The discovery of oxygen.
  • Importance of esters in our day-to-day living.

If you closely review the research topics for chemistry paper above, you will find them arousing your curiosity much more than the ones in other sections. These topics will challenge your initial line of thinking or introduce you to the concepts that just stand out.

Unique Chemistry Research Topics

There are some chemistry paper topics that are rarely worked on by students. People ignore these topics because they are either complex or lack adequate conclusive information from previous studies. If you are brave enough and wish to have a unique presentation, you can consider the research topics in chemistry below:

  • Organosilicon compounds and their use.
  • Nucleophiles and electrophiles.
  • Molecular structure of Teflon and its industrial application.
  • Sodium azide usage in automobile airbags.
  • Dangers of COVID-19 tests that use sodium azide as the reaction reagent.
  • Chemical composition of steroids and their effects on human beings.
  • Artificial diamond production process.
  • Insulin production biotechnology.
  • Evolution of lethal injection.
  • Effects of chiral class drugs on human health.
  • Chemical residues in livestock.
  • Artificial organs and their potential implication on transplantation.
  • Role of nanoreactors in nanotechnology and biotechnology.
  • Dangers of phosgene to human health.
  • Production of dry ice.

Popular Chemistry Research Paper Topics

Unlike the unique study subjects discussed in the previous section, popular topics relating to chemistry are widely researched. Students favor these topics due to reasons like their simplicity, availability of adequate evidence, and their relevance to current issues. You can pick a hot topic in chemistry from the list below:

  • Metal oxide usage in electronics.
  • Importance of nitrogen to human survival.
  • How do temperature changes affect chemical reactions?
  • Lewis structure for ionic compounds.
  • Analysis of the hydrophobic effect.
  • Hydrogen as an alternative to fossil fuel.
  • Application of thermodynamics law in our lives.
  • pH level calculations and analysis.
  • Gas laws and their application.
  • Why is Earth viewed as a closed thermodynamic system?
  • Redox reactions and their industrial applications.
  • Decomposition process of polymers.
  • The anomalous expansion of water.
  • Impact of fluoride ion on dental health .
  • The use of lithium, magnesium, and calcium compounds in clinical medicine.

>> View more: Medical Research Paper Topics

Controversial Chemistry Topics for Papers

Just like in any other subject, there exist chemistry project topics that are controversial in nature. People are understandably more passionate about some subject matters compared to others. Discussions related to, for instance, chemical usage in battlefields and the health effects of using certain chemicals tend to attract heated debates. Below are some controversial topics in chemistry that you can write about:

  • Biochemicals usage in warfare.
  • Impact of fast-food chemicals on the human brain.
  • Gene modification in human embryos.
  • Bioconjugation techniques and how they are used in drug delivery.
  • Synthetic molecules replication techniques.
  • Use of lethal injection in execution of criminals.
  • Ethical justification for euthanasia.
  • Manufacture of chemical poisons.
  • Fritz Haber’s controversial inventions.
  • Artificial organs and their role in healthcare.
  • Electromagnetic energy conversion to chemical energy.
  • Dangers of using fertilizer in farming.
  • Analyzing the water memory effect.
  • Synthesis of food from non-edible items.
  • Bio-inspired molecular machines and their applications.

Chemistry Research Ideas for Students

Students are often required to work on some chemistry project ideas to successfully complete their course. Depending on the sub-area one specializes in, and the academic level, research matters will vary significantly. For instance, chemistry undergraduate research project ideas are incomparable to highschool research titles. Some subject matters are only suitable for professional research. This section sorts the research ideas into their respective academic levels.

Chemistry Research Topics for High School

Chemistry research project ideas for highschool students are relatively easy compared to higher academic levels. The tasks are not very demanding in terms of the research methodologies used and the time required to complete them. At this level, students are introduced to the basic concepts of the subject. Common chemistry topics for high school are outlined in the list below.

  • Acids and bases in the reduction-oxidation reaction.
  • Importance of studying chemicals and chemical processes in high school.
  • Ionization techniques for the mass spectrometry process.
  • Avogadro’s Law: analysis, formulae, and application.
  • Thermochemistry lab experiments.
  • Laboratory safety rules.
  • The hydrolysis analysis.
  • Acids: structural composition, properties, and use.
  • Noble gasses configuration.
  • States of matter and their characteristics.
  • Optimizing indoor plants life through chemistry.
  • Role of enzymes in chemical and biological reactions.
  • Thermal effects of chemical reactions.
  • The law of multiple proportions in chemical reactions.
  • Constant and changing variables in Boyle’s law .

Chemistry Research Topics for College Students

Chemistry project ideas for college often require students to dive deep into a subject. Rather than explaining the basic concepts, you may be instructed to apply them in addressing problems. A college chemistry project will require you to dedicate more time and conduct more research. Below are some of the title ideas for college students and undergraduates:

  • How much energy is produced from burning nuts and chips?
  • Dangers of using radon in construction and potential solutions.
  • Chemical composition of aspirin and its effect on human physiology.
  • Green chemistry application in the food industry.
  • Phosphorescence versus fluorescence.
  • Dihydroxyacetone phosphate conversion.
  • Big data and biocomputing in chemical studies.
  • Thermoelectric properties of materials.
  • Artificial organic tissue development in laboratories.
  • Nuclear fusion: primary concepts and applications.
  • Power production process in lithium nickel batteries.
  • Medico-biological importance of group 3B and 4B elements.
  • Global cycle of biologically active elements.
  • Importance of chemical knowledge in cancer treatment.
  • Inorganic materials usage in the military.

Chemistry Research Topics in Different Fields

Chemistry can be divided into many sub-areas. Each subfield has interesting chemistry topics to research into. To choose a research topic in chemistry, you need to first determine a sub-area you would wish to specialize in. However, even within these fields, there are still many title options to choose from. To help reduce the confusion and simplify the selection process, we have categorized potential research discussions into their respective sub-areas.

Organic Chemistry Research Topics

Organic chemistry mainly involves studying the structure, composition, properties, and reaction of carbon-based compounds. It is among the most commercially applied subfields, which makes organic chemistry research paper topics very common. I am sure you must have encountered products manufactured using organic chemistry principles within your surroundings. If you wish to learn more about these products, you can explore these latest research topics in organic chemistry:

  • Pain relief medicine: chemical structure and composition.
  • Composition, use, and effects of polymers.
  • Retin-A usage in acne treatment.
  • Organic chemistry usage and application in daily life.
  • Types of organic compounds isomerism.
  • Aromatic hydrocarbons as industrial raw materials.
  • Alcohol hydrophilicity in aqueous solutions.
  • Physical and chemical properties of polyhydric alcohols.
  • Synthetic polymer applications: synthetic fiber, Teflon, and isoprene rubber.
  • Fetal alcohol syndrome: types and symptoms.
  • Structure and properties of phenols.
  • The application of organic chemistry in birth control.
  • Nucleic acid stability.
  • Parameters affecting proton chemical shifts.
  • Structure and properties of lipids.

Inorganic Chemistry Research Topics

This branch deals with the study of structure, composition, and properties of materials that do not contain carbon. Research paper topics for inorganic chemistry focus on metals, minerals, and inorganic compounds. The list below compiles chemistry projects topics and ideas related to inorganic chemistry.

  • How to create new and improve existing alloys.
  • Implication of inorganic chemistry on the environment.
  • Application of inorganic chemistry in the cosmetic industry.
  • Interaction between sulfuric acid and organic materials.
  • Lattice energy and enthalpy for different ionic bonds.
  • Characteristics of different types of nucleosyntheses.
  • Uniqueness of hydrogen bonds and polarity.
  • Hard and soft acids and bases ( HSAB ) theory.
  • Dalton’s Law: principles and applications.
  • Structure of a gemstone and how it impacts its appearance.
  • Relationship between inorganic and biochemistry.
  • Parameters affecting Bronsted-Lowry acidity.
  • Crystal field theory: analysis and disadvantages.
  • Application of angular overlap model.
  • Primary laws of photochemistry.

Analytical Chemistry Research Topics

The determination of the objects’ primary makeup of objects is the main interest of this branch. Various analytical methods, including spectroscopy, chromatography, and electroanalytical techniques, are often discussed in the subfield. As such, many analytical chemistry research paper topics focus on these or other analysis techniques. Below is a list of research topics on analytical chemistry:

  • Analytical techniques used in forensic science.
  • Examining the electroanalytical techniques.
  • Importance of analytical chemistry to the environment.
  • Miniaturization and its use in analyzing pharmaceutical substances.
  • Evaluating the working principles of activation analysis.
  • Gravimetric analysis principles.
  • GMOs usage and their potential hazards to human health.
  • Potentiometric measurement methods.
  • Liquid and gas chromatography.
  • Spectroscopy methods and their use in detecting and quantifying molecular and structural composition of samples.
  • Dispersive X-ray analysis of tissues.
  • Analytical methods for determining the side effects of ibuprofen usage.
  • Benefits of the isomerism framework.
  • Acid-base titration as a quantitative analysis technique.
  • Application of spectroscopy in medicine.

Environment Chemistry Topics for Research

The apparent global warming and climate change threats have led to the development of a new area of study. This sub-area has project topics in chemistry that explore the impact of human activity on the environment and the potential solutions for slowing down and reversing the climate change process. Common environmental chemistry related topics include:

  • Negative effects of deep-sea mining.
  • Ground water contamination: causes, dangers, and potential solutions.
  • Oil spillage and its effect on marine life.
  • Effect of heat engines on the environment.
  • Safe disposal of toxic waste.
  • Global warming: causes and potential remedies.
  • Potential alternatives to fossil fuels.
  • Innovative methods to minimize pesticide usage in agriculture.
  • Cultivated meat as an alternative to livestock farming.
  • How efficient is artificial photosynthesis.
  • The Chernobyl ecological disaster.
  • Analysis of life-cycle assessment (LCA).
  • Environmental benefits of using energy-saving lamps.
  • Environmental pollution by nano toxins.
  • Potential solutions for global warming.

Need more ideas on the environment? Check our list of the best environmental research topics for students. 

Physical Chemistry Research Topics

Physical chemistry is the study of the behavior of matter. Physical chemistry topics for research papers focus on analyzing the physical and chemical properties of atoms and molecules and how they interact with each other. You can use a project topic on chemistry from the list below:

  • Surface tension and its impact on mixtures.
  • Diffusion of liquid and gasses.
  • Reaction of bromine under UV rays.
  • Pressure effect in chemical reactions.
  • Bonding between atoms and molecules.
  • Analyzing Schrodinger’s equation.
  • Hess’s laws: principles and application.
  • Effects of intermolecular forces on the melting point of a material.
  • Entropy law of thermodynamics.
  • Relationship between quantum mechanics and atomic orbitals.
  • Chemical kinetics in pharmacy.
  • Analyzing the physical and chemical indicators of milk.
  • How to determine atoms’ electron configuration.
  • Why isotopes exist.
  • Determining the group based on its successive ionization energies.

Chemical Engineering Research Topics

In this section, we will discuss research topics of chemistry related to the design and application of chemical processes. Here are some of the chemical research project ideas that will impress your instructor:

  • Chemical engineering concepts in the food production industry.
  • Analyzing wastewater treatment techniques.
  • Conversion of rocket fuel to energy.
  • Analyzing different mixture separation techniques.
  • Industrial application of chemical engineering concepts.
  • Non-reactive mass balances and mass balance with reaction.
  • Binary distillation and its application.
  • Gas absorption usage in the chemical industry.
  • Reaction kinetics in a plug flow reactor.
  • Water splitting for hydrogen production.
  • The application of MIMO theory in the control of chemical process operation.
  • Chemical engineering applications in the healthcare sector.
  • Nanofiltration member usages in pharmaceutical wastewater treatment.
  • General overview of microfluidics.
  • Production of high-quality foam.

Nuclear Chemistry Research Topics

A nuclear chemistry research project deals with radioactivity-related processes. You may encounter this branch of science in nuclear energy production, military applications, and even in the hospital. Some of the researchable topics in chemistry of nuclei transformation include:

  • Computation of an element’s half-life.
  • Radioactive elements in real life and how they are being used.
  • Nuclear fusion: the process and its function.
  • Types of radioactive decay.
  • Effects of radiation on biological systems.
  • Safe radioactive waste disposal.
  • Application of nuclear science in the healthcare sector.
  • Analyzing the three types of radiation.
  • How to destroy toxic organic compounds using irradiation.
  • Is there a possibility of cold fusion ever happening?
  • Biological application of radiochemistry.
  • Dangerous consequences of ionizing versus non-ionizing radiation.
  • Optical chemo sensors: principles and applications.
  • Interaction between water and radioactive materials.
  • Radiation accident cases in human history.

There is a vast assortment of research ideas for your study on our platform. Be it biology research topics or nursing research paper topics , we have all of them here.

Bottom Line on Chemistry Research Topics

In sum, chemistry is a broad subject with multiple sub-areas. Depending on your preference, you can choose interesting chemistry research topics for papers from the many subfields. Apart from selecting a good research subject, also remember that is always mandatory to adhere to proper writing procedures! Besides, select chemistry essay topics that will keep you excited till the end of research, as you wouldn’t want to quit in the middle and switch to another topic. If you combine all provided tips together, you will definitely find it easy to select and work on research in chemistry topics.

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Collection  28 March 2018

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A new Hungarian method may aid protein research

by Eötvös Loránd University

A new Hungarian method may aid protein research

In a paper recently published in Nature Communications , the HUN-REN-ELTE Protein Modeling Research Group (Institute of Chemistry) has laid the foundations for a mathematical method, allowing the computer-assisted comparison of the three-dimensional structures of proteins. The method is unique in that while the alternatives available so far only took into account the position of the atoms, the new technique, called LoCoHD (Local Composition Hellinger Distance), also includes the chemical information of the atoms.

Proteins are molecular machines that carry out processes necessary for cells to function, acting as molecular switches, transcribing information from DNA, transporting small and large molecules and regulating metabolism related chemical reactions. However, for all this to succeed, the protein in question must have the right spatial conformation, i.e. its own, correct 3D arrangement.

Several experimental methods (X-ray crystallography, nuclear magnetic resonance spectroscopy , cryo-electron microscopy ) are available to determine the arrangement of atoms in a protein, and over the last few decades, protein researchers have discovered the shape of nearly 220,000 proteins. These results increasingly demand the development of computational methods capable of analyzing these arrangements.

One such method is the algorithm called LoCoHD, developed by Zsolt Fazekas, a Ph.D. candidate at the ELTE Hevesy György School of Chemistry and a researcher in Dr. András Perczel's research group. The algorithm compares local environments around amino acids in proteins based on their chemical nature (e.g., elemental composition, charge, hydrophobicity, etc.).

The method decides on a simple scale of 0 to 1 how different the structures in question are from each other. Values close to 0 suggest a high similarity between atomic arrangements and chemical properties, while values close to 1 indicate that the proteins being compared may have very different properties. The resulting numerical value (a so-called metric) can thus be used to obtain new information about the system under study.

The algorithm uses a multi-step protocol to generate the number representing the structural differences. In the first step, it converts real atoms in the protein into so-called primitive atoms. These can be represented as virtually labeled positions whose labels tell the chemical nature of the original atom.

A new Hungarian method may aid protein research

So, for example, a primitive atom can be a "positively charged nitrogen," a "negatively charged oxygen," a "neutrally charged oxygen," an "aromatic carbon," etc. The labels are generated according to a so-called primitive typing scheme, which tells us in a tabulated manner how to convert real atoms into primitive atoms. The user can freely specify this table, fixing the chemical resolution of the method.

The second step is to determine the reference points of the comparison by selecting a subset of primitive atoms. These selected special primitive atoms are called the anchor atoms. For each selected anchor atom pair, the algorithm performs a comparison step, the result of which gives the dissimilarity measure we want. These numbers can be used at a local level, or they can be averaged into a single descriptor characterizing the whole protein.

In the study, the researchers highlighted that the method can also be used in the biannual CASP (Critical Assessment of Protein Structure Prediction) competitions, which is a well known competition in the field of protein research. During this event, competitors use different algorithms to model the shape of proteins having yet unpublished structures. CASP judges use a number of structure comparison methods to evaluate the contenders, but none of these take into account the chemistry of the local amino acid environments.

Using data from the 2020 CASP14 competition, the researchers have now performed comparative analysis of several modeled proteins, including the structures predicted by the artificial-intelligence-based AlphaFold2 method. Among these, they highlighted the analysis of a protein from the SARS-CoV-2 virus called ORF8. In the modeled structures of this protein, amino acid environments were identified that differ significantly in their interaction patterns from the environments found in the experimental structure.

In addition to studying static structures, the researchers also tested whether the method is suitable for analyzing the internal motion of proteins. They used simulations capable of reproducing molecular motions and data extracted from structural ensembles. One of the systems under study was the podocin protein, which performs vital functions in the kidney and whose mutations can cause severe, often fatal conditions.

The LoCoHD method was used to identify amino acids in the protein that undergo major chemical-environmental changes during the movement of podocin, which can affect both its structure and function. Similarly, the LoCoHD method has been applied successfully in the study of the HIV-1 capsid protein, in which an amino acid critical for the formation of the viral envelope has been identified.

These results are not only research curiosities, but by studying protein structures more effectively, we can get closer to better understanding the pathogens causing severe diseases and to developing effective drugs and therapeutics.

Journal information: Nature Communications

Provided by Eötvös Loránd University

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Adhesive coatings can prevent scarring around medical implants

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An open notebook shows illustrations of the heart, liver, and intestines with translucent bandages.

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Images for download on the MIT News office website are made available to non-commercial entities, press and the general public under a Creative Commons Attribution Non-Commercial No Derivatives license . You may not alter the images provided, other than to crop them to size. A credit line must be used when reproducing images; if one is not provided below, credit the images to "MIT."

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When medical devices such as pacemakers are implanted in the body, they usually provoke an immune response that leads to buildup of scar tissue around the implant. This scarring, known as fibrosis, can interfere with the devices’ function and may require them to be removed.

In an advance that could prevent that kind of device failure, MIT engineers have found a simple and general way to eliminate fibrosis by coating devices with a hydrogel adhesive. This adhesive binds the devices to tissue and prevents the immune system from attacking it.

“The dream of many research groups and companies is to implant something into the body that over the long term the body will not see, and the device can provide therapeutic or diagnostic functionality. Now we have such an ‘invisibility cloak,’ and this is very general: There’s no need for a drug, no need for a special polymer,” says Xuanhe Zhao, an MIT professor of mechanical engineering and of civil and environmental engineering.

The adhesive that the researchers used in this study is made from cross-linked polymers called hydrogels, and is similar to a surgical tape they previously developed to help seal internal wounds. Other types of hydrogel adhesives can also protect against fibrosis, the researchers found, and they believe this approach could be used for not only pacemakers but also sensors or devices that deliver drugs or therapeutic cells.

Zhao and Hyunwoo Yuk SM ’16, PhD ’21, a former MIT research scientist who is now the chief technology officer at SanaHeal, are the senior authors of the study, which appears today in Nature . MIT postdoc Jingjing Wu is the lead author of the paper.

Preventing fibrosis

In recent years, Zhao’s lab has developed adhesives for a variety of medical applications, including double-sided and single-sided tapes that could be used to heal surgical incisions or internal injuries. These adhesives work by rapidly absorbing water from wet tissues, using polyacrylic acid, an absorbent material used in diapers. Once the water is cleared, chemical groups called NHS esters embedded in the polyacrylic acid form strong bonds with proteins at the tissue surface. This process takes about five seconds.

Several years ago, Zhao and Yuk began exploring whether this kind of adhesive could also help keep medical implants in place and prevent fibrosis from occurring.

To test this idea, Wu coated polyurethane devices with their adhesive and implanted them on the abdominal wall, colon, stomach, lung, or heart of rats. Weeks later, they removed the device and found that there was no visible scar tissue. Additional tests with other animal models showed the same thing: Wherever the adhesive-coated devices were implanted, fibrosis did not occur, for up to three months.

“This work really has identified a very general strategy, not only for one animal model, one organ, or one application,” Wu says. “Across all of these animal models, we have consistent, reproducible results without any observable fibrotic capsule.”

Using bulk RNA sequencing and fluorescent imaging, the researchers analyzed the animals’ immune response and found that when devices with adhesive coatings were first implanted, immune cells such as neutrophils began to infiltrate the area. However, the attacks quickly quenched out before any scar tissue could form.

“For the adhered devices, there is an acute inflammatory response because it is a foreign material,” Yuk says. “However, very quickly that inflammatory response decayed, and then from that point you do not have this fibrosis formation.”

One application for this adhesive could be coatings for epicardial pacemakers — devices that are placed on the heart to help control the heart rate. The wires that contact the heart often become fibrotic, but the MIT team found that when they implanted adhesive-coated wires in rats, they remained functional for at least three months, with no scar tissue formation.

“The formation of fibrotic tissue at the interface between implanted medical devices and the target tissue is a longstanding problem that routinely causes failure of the device. The demonstration that robust adhesion between the device and the tissue obviates fibrotic tissue formation is an important observation that has many potential applications in the medical device space,” says David Mooney, a professor of bioengineering at Harvard University, who was not involved in the study.

Mechanical cues

The researchers also tested a hydrogel adhesive that includes chitosan, a naturally occurring polysaccharide, and found that this adhesive also eliminated fibrosis in animal studies. However, two commercially available tissue adhesives that they tested did not show this antifibrotic effect because the commercially available adhesives eventually detached from the tissue and allowed the immune system to attack.

In another experiment, the researchers coated implants in hydrogel adhesives but then soaked them in a solution that removed the polymers’ adhesive properties, while keeping their overall chemical structure the same. After being implanted in the body, where they were held in place by sutures, fibrotic scarring occurred. This suggests that there is something about the mechanical interaction between the adhesive and the tissue that prevents the immune system from attacking, the researchers say.

“Previous research in immunology has been focused on chemistry and biochemistry, but mechanics and physics may play equivalent roles, and we should pay attention to those mechanical and physical cues in immunological responses,” says Zhao, who now plans to further investigate how those mechanical cues affect the immune system.

Yuk, Zhao, and others have started a company called SanaHeal, which is now working on further developing tissue adhesives for medical applications.

“As a team, we are interested in reporting this to the community and sparking speculation and imagination as to where this can go,” Yuk says. “There are so many scenarios in which people want to interface with foreign or manmade material in the body, like implantable devices, drug depots, or cell depots.”

The research was funded by the National Institutes of Health and the National Science Foundation.

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MIT engineers have developed a new adhesive, low-cost hydrogel that can stop fibrosis often experienced by people with pacemakers and other medical devices, reports for Maria Bolevich Interesting Engineering . “These findings may offer a promising strategy for long-term anti-fibrotic implant–tissue interfaces,” explains Prof. Xuanhe Zhao. 

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